DE19608753C1 - Transduktionssystem und seine Verwendung - Google Patents

Transduktionssystem und seine Verwendung

Info

Publication number
DE19608753C1
DE19608753C1 DE19608753A DE19608753A DE19608753C1 DE 19608753 C1 DE19608753 C1 DE 19608753C1 DE 19608753 A DE19608753 A DE 19608753A DE 19608753 A DE19608753 A DE 19608753A DE 19608753 C1 DE19608753 C1 DE 19608753C1
Authority
DE
Germany
Prior art keywords
rep
transduction system
cells
dna
aav
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE19608753A
Other languages
German (de)
English (en)
Inventor
Gerd Dr Maass
Christoph Dr Bogedain
Michael Dr Hallek
Clemens Dr Wendtner
Doris Dr Michl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medigene AG
Original Assignee
Medigene AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medigene AG filed Critical Medigene AG
Priority to DE19608753A priority Critical patent/DE19608753C1/de
Priority to JP9531353A priority patent/JP2000506726A/ja
Priority to EP97918010A priority patent/EP0891429A2/de
Priority to PCT/DE1997/000447 priority patent/WO1997032989A2/de
Priority to US09/142,289 priority patent/US6207453B1/en
Application granted granted Critical
Publication of DE19608753C1 publication Critical patent/DE19608753C1/de
Priority to US09/773,302 priority patent/US6440742B1/en
Priority to US10/218,280 priority patent/US20020192826A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE19608753A 1996-03-06 1996-03-06 Transduktionssystem und seine Verwendung Expired - Fee Related DE19608753C1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE19608753A DE19608753C1 (de) 1996-03-06 1996-03-06 Transduktionssystem und seine Verwendung
JP9531353A JP2000506726A (ja) 1996-03-06 1997-03-06 組換えａａｖベクターに基づく形質導入系およびその使用
EP97918010A EP0891429A2 (de) 1996-03-06 1997-03-06 Transduktionssystem beruhend auf rekombinantem aav-vektor und seine verwendung
PCT/DE1997/000447 WO1997032989A2 (de) 1996-03-06 1997-03-06 Transduktionssystem beruhend auf rekombinantem aav-vektor und seine verwendung
US09/142,289 US6207453B1 (en) 1996-03-06 1997-03-06 Recombinant AAV vector-based transduction system and use of same
US09/773,302 US6440742B1 (en) 1996-03-06 2001-01-31 Recombinant AAV vector-based transduction system and use of same
US10/218,280 US20020192826A1 (en) 1996-03-06 2002-08-12 Recombinant AAV vector-based transduction system and use of same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19608753A DE19608753C1 (de) 1996-03-06 1996-03-06 Transduktionssystem und seine Verwendung

Publications (1)

Publication Number Publication Date
DE19608753C1 true DE19608753C1 (de) 1997-06-26

Family

ID=7787450

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19608753A Expired - Fee Related DE19608753C1 (de) 1996-03-06 1996-03-06 Transduktionssystem und seine Verwendung

Country Status (5)

Country Link
US (3) US6207453B1 (enExample)
EP (1) EP0891429A2 (enExample)
JP (1) JP2000506726A (enExample)
DE (1) DE19608753C1 (enExample)
WO (1) WO1997032989A2 (enExample)

Families Citing this family (196)

* Cited by examiner, † Cited by third party
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WO2005044932A1 (en) * 2003-11-11 2005-05-19 Canon Kabushiki Kaisha An ink comprising a block copolymer dispersing agent having a hydrophilic and a hydrophobic segment and an ink-applying process and apparatus using the same
EP1755400A2 (en) * 2004-06-18 2007-02-28 The University Of Montana Aav mediated gene delivery to cochlear cells
US20100080784A1 (en) * 2008-09-12 2010-04-01 Torrey Pines Institute For Molecular Studies Methods for treating cachexia and lymphopenia
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