DD216929A5 - Verfahren zur herstellung von thiazolidinderivaten - Google Patents

Verfahren zur herstellung von thiazolidinderivaten Download PDF

Info

Publication number
DD216929A5
DD216929A5 DD84260939A DD26093984A DD216929A5 DD 216929 A5 DD216929 A5 DD 216929A5 DD 84260939 A DD84260939 A DD 84260939A DD 26093984 A DD26093984 A DD 26093984A DD 216929 A5 DD216929 A5 DD 216929A5
Authority
DD
German Democratic Republic
Prior art keywords
general formula
thiazolidine
ppm
group
cyanimino
Prior art date
Application number
DD84260939A
Other languages
German (de)
English (en)
Inventor
Elemer Ezer
Kalman Harsanyi
Gyoergy Domany
Laszlo Szporny
Judit Matuz
Bela Hegedues
Katalin Pallagi
Istvan Szabadkai
Peter Tetenyi
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DD216929A5 publication Critical patent/DD216929A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
DD84260939A 1983-03-16 1984-03-15 Verfahren zur herstellung von thiazolidinderivaten DD216929A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU83888A HU188852B (en) 1983-03-16 1983-03-16 Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer

Publications (1)

Publication Number Publication Date
DD216929A5 true DD216929A5 (de) 1985-01-02

Family

ID=10951891

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84260939A DD216929A5 (de) 1983-03-16 1984-03-15 Verfahren zur herstellung von thiazolidinderivaten

Country Status (32)

Country Link
US (1) US4616025A (nl)
JP (1) JPS59196877A (nl)
KR (1) KR840008001A (nl)
AT (1) AT383596B (nl)
AU (1) AU559753B2 (nl)
BE (1) BE899132A (nl)
CA (1) CA1273933A (nl)
CH (1) CH660592A5 (nl)
CS (1) CS241074B2 (nl)
DD (1) DD216929A5 (nl)
DE (1) DE3409801A1 (nl)
DK (1) DK143284A (nl)
ES (2) ES530738A0 (nl)
FI (1) FI79843C (nl)
FR (1) FR2542740B1 (nl)
GB (1) GB2140412B (nl)
GR (1) GR81883B (nl)
HU (1) HU188852B (nl)
IE (1) IE57101B1 (nl)
IL (1) IL71249A (nl)
IN (1) IN157738B (nl)
IT (1) IT1196048B (nl)
LU (1) LU85248A1 (nl)
NL (1) NL8400817A (nl)
NO (1) NO162858C (nl)
NZ (1) NZ207516A (nl)
PL (2) PL142909B1 (nl)
PT (1) PT78260B (nl)
SE (1) SE455945B (nl)
SU (2) SU1240355A3 (nl)
YU (1) YU47384A (nl)
ZA (1) ZA841938B (nl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051184A (ja) * 1983-08-30 1985-03-22 Fujimoto Seiyaku Kk Ν−シアノイミノチアゾリジン誘導体およびその製造法
JPH0730070B2 (ja) * 1985-10-03 1995-04-05 日本バイエルアグロケム株式会社 新規複素環式化合物
JPH066585B2 (ja) * 1985-02-04 1994-01-26 日本バイエルアグロケム株式会社 ニトロメチレン誘導体、その製法及び殺虫剤
US5001138B1 (en) * 1985-02-04 1998-01-20 Bayer Agrochem Kk Heterocyclic compounds
US5204360A (en) * 1985-02-04 1993-04-20 Nihon Bayer Agrochem K.K. Heterocyclic compounds
JPH0649699B2 (ja) * 1985-02-04 1994-06-29 日本バイエルアグロケム株式会社 ニトロメチレン誘導体、その製法及び殺虫剤
ATE67493T1 (de) 1985-02-04 1991-10-15 Bayer Agrochem Kk Heterocyclische verbindungen.
JPH0717621B2 (ja) * 1986-03-07 1995-03-01 日本バイエルアグロケム株式会社 新規ヘテロ環式化合物
USRE39130E1 (en) 1986-03-07 2006-06-13 Bayer Cropscience K.K. Heterocyclic compounds
JP2607369B2 (ja) * 1987-02-20 1997-05-07 興和株式会社 新規な複素環化合物
US5122522A (en) * 1989-06-21 1992-06-16 The Trustees Of The University Of Pennsylvania Treatment and control of ocular development
DE69033246T2 (de) * 1989-06-21 1999-12-02 Univ Pennsylvania Behandlung und Regulierung der Augenentwicklung mit cholinergischen Agonisten
HU207047B (en) * 1989-11-07 1993-03-01 Richter Gedeon Vegyeszet Process for producing new pyridine derivatives and pharmaceutical copositions comprising same
CA2063865A1 (en) * 1992-03-24 1993-09-25 Karoly Lempert 2-(substituted imino)-thiazolidines and process for the preparation thereof
JP2721805B2 (ja) * 1994-07-22 1998-03-04 日本バイエルアグロケム株式会社 新規ヘテロ環式化合物
DE4427539A1 (de) * 1994-08-04 1996-02-08 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von 2-Cyaniminothiazolidin
DE4427569A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Verfahren zur Herstellung von Cyanimino-1,3-thiazolidin
DE19904310A1 (de) * 1999-01-28 2000-08-03 Bayer Ag Verfahren zur Herstellung heterocyclischer Verbindungen
CN1198803C (zh) * 1999-03-05 2005-04-27 第一三得利制药株式会社 具有激活烟碱性乙酰胆碱α4β2受体作用的杂环化合物
KR20040018380A (ko) * 2001-05-25 2004-03-03 밸리 포지 파마슈티컬즈, 인크. 피렌제핀 안약 겔제
SI1567112T1 (sl) * 2002-11-22 2009-02-28 Smithkline Beecham Corp Thiazolidin-4-oni za inhibiranje proteinov hyak3
JP4847314B2 (ja) * 2003-04-07 2011-12-28 コーティカル・ピーティーワイ・リミテッド 炎症性疾患を治療するための新規な方法
EP2305658B9 (en) * 2008-07-01 2015-04-29 Meiji Seika Pharma Co., Ltd. Novel imino derivative, process for production of the same, and pesticide comprising the same
ES2556470T3 (es) * 2011-09-02 2016-01-18 Bayer Intellectual Property Gmbh Procedimiento para preparar [3-[(6-cloro-3-piridinil)metil]-2-tiazolidiniliden]cianamida

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264316A (en) * 1963-09-18 1966-08-02 Res Lab Dr C Janssen N V Certain 2-acylimino-3-substitutedthiazoline-4 compounds
DE2205745A1 (de) * 1972-02-08 1973-08-23 Thomae Gmbh Dr K Neue durch den n-cyaniminorest substituierten heterocyclen und verfahren zu ihrer herstellung
US4006156A (en) * 1975-06-27 1977-02-01 Shell Oil Company 3-Alkyl-2-(nitromethylene) thiazolidine
DK173777A (da) * 1976-05-03 1977-11-04 Merck & Co Inc Fremgangsmade til fremstilling af derivater af 2-iminothiazolidiner og thiazoliner
JPS57171986A (en) * 1981-04-14 1982-10-22 Taiho Yakuhin Kogyo Kk Heterocylic ring compound containing sulfur
JPS5823682A (ja) * 1981-08-03 1983-02-12 Santen Pharmaceut Co Ltd 複素五員環化合物
DE3133918A1 (de) * 1981-08-27 1983-03-17 Bayer Ag, 5090 Leverkusen 2-arylhydrazino-2-thiazoline, acylderivate derselben, 2-arylazo-2-thiazoline, herstellungsverfahren und ihre verwendung zur bekaempfung von ekto- und endoparasiten
JPS58222886A (ja) * 1982-06-19 1983-12-24 Ricoh Co Ltd 感熱記録シ−ト
JPS5933267A (ja) * 1982-08-19 1984-02-23 Fujimoto Seiyaku Kk グアニジン誘導体およびその製造法

Also Published As

Publication number Publication date
PT78260B (en) 1986-04-30
CA1273933A (en) 1990-09-11
GB2140412A (en) 1984-11-28
NZ207516A (en) 1986-06-11
PL252129A1 (en) 1985-11-19
CH660592A5 (de) 1987-05-15
CS188584A2 (en) 1985-06-13
FI841066A0 (fi) 1984-03-16
ES8604179A1 (es) 1986-01-16
NO162858C (no) 1990-02-28
SE455945B (sv) 1988-08-22
IN157738B (nl) 1986-05-31
NL8400817A (nl) 1984-10-16
GB8406790D0 (en) 1984-04-18
ZA841938B (en) 1985-05-29
NO841002L (no) 1984-09-17
IT8420057A0 (it) 1984-03-15
ES544286A0 (es) 1986-01-16
ATA88284A (de) 1986-12-15
DK143284A (da) 1984-09-17
AU559753B2 (en) 1987-03-19
PL142749B1 (en) 1987-11-30
SE8401463D0 (sv) 1984-03-15
HU188852B (en) 1986-05-28
FI79843B (fi) 1989-11-30
FI79843C (fi) 1990-03-12
PT78260A (en) 1984-04-01
ES8601170A1 (es) 1985-11-01
IE840655L (en) 1984-09-16
ES530738A0 (es) 1985-11-01
DK143284D0 (da) 1984-02-29
PL246683A1 (en) 1985-07-16
FI841066A (fi) 1984-09-17
BE899132A (fr) 1984-09-12
IE57101B1 (en) 1992-04-22
LU85248A1 (fr) 1985-10-14
SU1240355A3 (ru) 1986-06-23
GB2140412B (en) 1987-02-11
AT383596B (de) 1987-07-27
SU1240356A3 (ru) 1986-06-23
DE3409801A1 (de) 1984-09-20
US4616025A (en) 1986-10-07
SE8401463L (sv) 1984-09-17
IL71249A (en) 1987-02-27
FR2542740B1 (fr) 1987-02-20
GR81883B (nl) 1984-12-12
CS241074B2 (en) 1986-03-13
AU2583384A (en) 1984-09-20
IT1196048B (it) 1988-11-10
FR2542740A1 (fr) 1984-09-21
NO162858B (no) 1989-11-20
PL142909B1 (en) 1987-12-31
KR840008001A (ko) 1984-12-12
IL71249A0 (en) 1984-06-29
YU47384A (nl) 1986-10-31
JPS59196877A (ja) 1984-11-08

Similar Documents

Publication Publication Date Title
DD216929A5 (de) Verfahren zur herstellung von thiazolidinderivaten
DE2734070C2 (de) Aminoalkylfuranderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3218584C2 (nl)
DE3204596C2 (nl)
DE2322880C2 (de) 4-(Imidazolin-2-ylamino)-2,1,3-benzothiadiazole und Verfahren zu deren Herstellung
DE1695186A1 (de) Verfahren zur Herstellung von Imidazolderivaten
DE2805166A1 (de) Neue entzuendungshemmende imidazolverbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DD237658A5 (de) Verfahren zur herstellung verbesserter entzuendungshemmender salze von piroxicam
DE2238504B2 (de) l-Phenoxy-3-alkylaminopropan-2-ol -Derivate
DD207913A5 (de) Verfahren zur herstellung von 2-guanidino-4-heteroarylthiazolen
DE3216843C2 (de) 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3309655A1 (de) 1,2,5-thiadiazol-1-oxide und 1,1-dioxide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2755771A1 (de) Derivate des 4-oxo-imidazolins, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0027268A2 (de) Chinazolin-Derivate, Verfahren und Zwischenprodukte zu deren Herstellung, Arzneimittel enthaltend solche Chinazolin-Derivate und deren pharmazeutische Verwendung
DE2344611A1 (de) 5-(substituierte phenoxy)-4-aminound -substituierte aminopyrimidine
DE2457309A1 (de) 2-phenylhydrazinothiazolin- beziehungsweise 2-phenylhydrazinothiazininderivate sowie ihre verwendung und verfahren zur herstellung derselben
DE2824066A1 (de) Neue, zur ulcusbehandlung brauchbare verbindungen, verfahren zu deren herstellung, arzneimittel und zwischenprodukte
DE3426533A1 (de) 1,3,4-thiadiazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0030343B1 (de) Substituierte 2-Amino-3,4-dihydropyridinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE2419198A1 (de) Pyridincarboxamidsulfonylharnstoffe als hypoglykaemische mittel
DE3142559A1 (de) "pyrimidin-derivate"
CH579565A5 (en) Imidazolin-2-ylamino-2,1,3-benzothiadiazoles prodn. - by cyclising corresp. beta aminoethyl (thio) ureas, active against muscle tremors and rigor
DE2335507C2 (de) Sulfamylbenzoesäurederivate, Verfahren zu deren Herstellung und sie enthaltendes pharmazeutisches Mittel
DE3413876A1 (de) Arzneimittel
DE2845624A1 (de) Neue derivate des thiazolins, ihre herstellung und die sie enthaltenden zusammensetzungen

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee