ES8601170A1 - Procedimiento para la preparacion de nuevos derivados tiazolidinicos - Google Patents

Procedimiento para la preparacion de nuevos derivados tiazolidinicos

Info

Publication number
ES8601170A1
ES8601170A1 ES530738A ES530738A ES8601170A1 ES 8601170 A1 ES8601170 A1 ES 8601170A1 ES 530738 A ES530738 A ES 530738A ES 530738 A ES530738 A ES 530738A ES 8601170 A1 ES8601170 A1 ES 8601170A1
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical compositions
thiazolidine derivatives
thiazolidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530738A
Other languages
English (en)
Other versions
ES530738A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES530738A0 publication Critical patent/ES530738A0/es
Publication of ES8601170A1 publication Critical patent/ES8601170A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS TIAZOLIDINICOS DE FORMULA (I) EN LA QUE Y ES NITROGENO O CH; Z ES CIANO CARBAMOILO O NITRO; Y AR PUEDE SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN DERIVADO 1-AMINO-2-TIOL N-SUSTITUIDO DE FORMULA HS-CH2-CH2-NH-CH2-AR CON UN COMPUESTO DE FORMULA L2CFY-Z EN LAS QUE L ES UN GRUPO SALIENTE Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE A UNA TEMPERATURA ENTRE 40JC Y 80JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ULCERAS GASTROINTESTINALES.
ES530738A 1983-03-16 1984-03-16 Procedimiento para la preparacion de nuevos derivados tiazolidinicos Expired ES8601170A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU83888A HU188852B (en) 1983-03-16 1983-03-16 Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer

Publications (2)

Publication Number Publication Date
ES530738A0 ES530738A0 (es) 1985-11-01
ES8601170A1 true ES8601170A1 (es) 1985-11-01

Family

ID=10951891

Family Applications (2)

Application Number Title Priority Date Filing Date
ES530738A Expired ES8601170A1 (es) 1983-03-16 1984-03-16 Procedimiento para la preparacion de nuevos derivados tiazolidinicos
ES544286A Expired ES8604179A1 (es) 1983-03-16 1985-06-17 Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES544286A Expired ES8604179A1 (es) 1983-03-16 1985-06-17 Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos

Country Status (32)

Country Link
US (1) US4616025A (es)
JP (1) JPS59196877A (es)
KR (1) KR840008001A (es)
AT (1) AT383596B (es)
AU (1) AU559753B2 (es)
BE (1) BE899132A (es)
CA (1) CA1273933A (es)
CH (1) CH660592A5 (es)
CS (1) CS241074B2 (es)
DD (1) DD216929A5 (es)
DE (1) DE3409801A1 (es)
DK (1) DK143284A (es)
ES (2) ES8601170A1 (es)
FI (1) FI79843C (es)
FR (1) FR2542740B1 (es)
GB (1) GB2140412B (es)
GR (1) GR81883B (es)
HU (1) HU188852B (es)
IE (1) IE57101B1 (es)
IL (1) IL71249A (es)
IN (1) IN157738B (es)
IT (1) IT1196048B (es)
LU (1) LU85248A1 (es)
NL (1) NL8400817A (es)
NO (1) NO162858C (es)
NZ (1) NZ207516A (es)
PL (2) PL142909B1 (es)
PT (1) PT78260B (es)
SE (1) SE455945B (es)
SU (2) SU1240355A3 (es)
YU (1) YU47384A (es)
ZA (1) ZA841938B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051184A (ja) * 1983-08-30 1985-03-22 Fujimoto Seiyaku Kk Ν−シアノイミノチアゾリジン誘導体およびその製造法
US5001138B1 (en) * 1985-02-04 1998-01-20 Bayer Agrochem Kk Heterocyclic compounds
EP0192060B1 (de) * 1985-02-04 1991-09-18 Nihon Bayer Agrochem K.K. Heterocyclische Verbindungen
JPH066585B2 (ja) * 1985-02-04 1994-01-26 日本バイエルアグロケム株式会社 ニトロメチレン誘導体、その製法及び殺虫剤
JPH0649699B2 (ja) * 1985-02-04 1994-06-29 日本バイエルアグロケム株式会社 ニトロメチレン誘導体、その製法及び殺虫剤
JPH0730070B2 (ja) * 1985-10-03 1995-04-05 日本バイエルアグロケム株式会社 新規複素環式化合物
US5204360A (en) * 1985-02-04 1993-04-20 Nihon Bayer Agrochem K.K. Heterocyclic compounds
USRE39130E1 (en) 1986-03-07 2006-06-13 Bayer Cropscience K.K. Heterocyclic compounds
JPH0717621B2 (ja) * 1986-03-07 1995-03-01 日本バイエルアグロケム株式会社 新規ヘテロ環式化合物
JP2607369B2 (ja) * 1987-02-20 1997-05-07 興和株式会社 新規な複素環化合物
US5122522A (en) * 1989-06-21 1992-06-16 The Trustees Of The University Of Pennsylvania Treatment and control of ocular development
ATE203666T1 (de) * 1989-06-21 2001-08-15 Univ Pennsylvania Verwendung eines muskarinantagonists zur herstellung eines medikaments für die behandlung und regulierung der augenentwicklung
HU207047B (en) * 1989-11-07 1993-03-01 Richter Gedeon Vegyeszet Process for producing new pyridine derivatives and pharmaceutical copositions comprising same
CA2063865A1 (en) * 1992-03-24 1993-09-25 Karoly Lempert 2-(substituted imino)-thiazolidines and process for the preparation thereof
JP2721805B2 (ja) * 1994-07-22 1998-03-04 日本バイエルアグロケム株式会社 新規ヘテロ環式化合物
DE4427569A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Verfahren zur Herstellung von Cyanimino-1,3-thiazolidin
DE4427539A1 (de) * 1994-08-04 1996-02-08 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von 2-Cyaniminothiazolidin
DE19904310A1 (de) * 1999-01-28 2000-08-03 Bayer Ag Verfahren zur Herstellung heterocyclischer Verbindungen
WO2000053582A1 (en) * 1999-03-05 2000-09-14 Suntory Limited HETEROCYCLIC COMPOUNDS HAVING EFFECT OF ACTIVATING NICOTINIC ACETYLCHOLINE α4β2 RECEPTOR
WO2002096418A1 (en) * 2001-05-25 2002-12-05 Valley Forge Pharmaceuticals Pirenzepine ophthalmic gel
AU2003298693B2 (en) * 2002-11-22 2010-09-30 Smithkline Beecham Corporation Novel chemical compounds
JP4847314B2 (ja) * 2003-04-07 2011-12-28 コーティカル・ピーティーワイ・リミテッド 炎症性疾患を治療するための新規な方法
NZ590757A (en) 2008-07-01 2014-05-30 Univ Gifu Novel imino derivative, process for production of the same, and pesticide comprising the same
BR112014004852A2 (pt) * 2011-09-02 2017-04-04 Bayer Ip Gmbh processo para a preparação de [3-[(6-cloro-3-piridinil)-metil]-2-tiazolidinilideno]-cianamida

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264316A (en) * 1963-09-18 1966-08-02 Res Lab Dr C Janssen N V Certain 2-acylimino-3-substitutedthiazoline-4 compounds
DE2205745A1 (de) * 1972-02-08 1973-08-23 Thomae Gmbh Dr K Neue durch den n-cyaniminorest substituierten heterocyclen und verfahren zu ihrer herstellung
US4006156A (en) * 1975-06-27 1977-02-01 Shell Oil Company 3-Alkyl-2-(nitromethylene) thiazolidine
NL7704322A (nl) * 1976-05-03 1977-11-07 Merck & Co Inc Werkwijze voor het bereiden van 2-iminothiazo- lidinen en -thiazolinen.
JPS57171986A (en) * 1981-04-14 1982-10-22 Taiho Yakuhin Kogyo Kk Heterocylic ring compound containing sulfur
JPS5823682A (ja) * 1981-08-03 1983-02-12 Santen Pharmaceut Co Ltd 複素五員環化合物
DE3133918A1 (de) * 1981-08-27 1983-03-17 Bayer Ag, 5090 Leverkusen 2-arylhydrazino-2-thiazoline, acylderivate derselben, 2-arylazo-2-thiazoline, herstellungsverfahren und ihre verwendung zur bekaempfung von ekto- und endoparasiten
JPS58222886A (ja) * 1982-06-19 1983-12-24 Ricoh Co Ltd 感熱記録シ−ト
JPS5933267A (ja) * 1982-08-19 1984-02-23 Fujimoto Seiyaku Kk グアニジン誘導体およびその製造法

Also Published As

Publication number Publication date
ES544286A0 (es) 1986-01-16
ES530738A0 (es) 1985-11-01
US4616025A (en) 1986-10-07
CS241074B2 (en) 1986-03-13
IE840655L (en) 1984-09-16
LU85248A1 (fr) 1985-10-14
PT78260B (en) 1986-04-30
DD216929A5 (de) 1985-01-02
DE3409801A1 (de) 1984-09-20
NO162858C (no) 1990-02-28
IN157738B (es) 1986-05-31
GR81883B (es) 1984-12-12
AU2583384A (en) 1984-09-20
GB8406790D0 (en) 1984-04-18
NL8400817A (nl) 1984-10-16
PL142749B1 (en) 1987-11-30
NO162858B (no) 1989-11-20
ES8604179A1 (es) 1986-01-16
PL142909B1 (en) 1987-12-31
SE8401463L (sv) 1984-09-17
AU559753B2 (en) 1987-03-19
FI79843C (fi) 1990-03-12
FR2542740B1 (fr) 1987-02-20
CA1273933A (en) 1990-09-11
IT1196048B (it) 1988-11-10
FI841066A0 (fi) 1984-03-16
ZA841938B (en) 1985-05-29
PL252129A1 (en) 1985-11-19
DK143284D0 (da) 1984-02-29
JPS59196877A (ja) 1984-11-08
ATA88284A (de) 1986-12-15
IT8420057A0 (it) 1984-03-15
NO841002L (no) 1984-09-17
PL246683A1 (en) 1985-07-16
KR840008001A (ko) 1984-12-12
IE57101B1 (en) 1992-04-22
SU1240356A3 (ru) 1986-06-23
GB2140412A (en) 1984-11-28
FR2542740A1 (fr) 1984-09-21
SE455945B (sv) 1988-08-22
SE8401463D0 (sv) 1984-03-15
FI841066A (fi) 1984-09-17
CS188584A2 (en) 1985-06-13
AT383596B (de) 1987-07-27
PT78260A (en) 1984-04-01
SU1240355A3 (ru) 1986-06-23
BE899132A (fr) 1984-09-12
HU188852B (en) 1986-05-28
IL71249A (en) 1987-02-27
NZ207516A (en) 1986-06-11
GB2140412B (en) 1987-02-11
DK143284A (da) 1984-09-17
YU47384A (es) 1986-10-31
IL71249A0 (en) 1984-06-29
FI79843B (fi) 1989-11-30
CH660592A5 (de) 1987-05-15

Similar Documents

Publication Publication Date Title
ES8604179A1 (es) Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos
DE3865112D1 (de) Azolylmethyl-cyclopropyl-derivate.
ES2054826T3 (es) Peptidos con actividad inhibidora de colagenasa.
IE43731L (en) Triazolyl and imidazolyl derivatives
DE2960820D1 (en) Carbostyrile derivatives, processes for their preparation and pharmaceutical compositions containing them
PT91607A (pt) Process for the preparation of substituted beta-diketones and of pharmaceutical compositions containing them
JPS5681578A (en) Novel thioalkyl amide derivative
ES8602650A1 (es) Procedimiento para la preparacion de nuevos derivados de 3-fenil-4-cianopirrol
ATE107280T1 (de) Carbamoyl-2-pyrrolidinonverbindungen.
DE2965701D1 (en) 1-imidazol-2-ylidene-3-thienyl-urea derivatives, processes therefor, and pharmaceutical compositions
DK508484A (da) N-substituerede isoquinolinderivater og farmaceutisk praeparat indeholdende dem
NO911508D0 (no) Nytt s-timoloderivat og fremgangsmaate for dets fremstilling.
DK0426562T3 (da) 1-(4-aminophenyl)-2-piperidinopropanonderivater, fremgangsmåde til fremstilling heraf samt deres terapeutiske anvendelse
ES8604118A1 (es) Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo n-carbamiloxi sustituido
DE3470312D1 (de) Ether of n-propanolamine derivative
ES8604121A1 (es) Procedimiento para la preparacion de esteres de acido guani-dinobenzoico
ES8201531A1 (es) Procedimiento de preparar alcoxi propanolaminas
ES8301478A1 (es) Un procedimiento para preparar derivados de indol
NO922636L (no) Fremgangsmaate for fremstilling av 2,4-dihydro-2-alkyl-3-okso-2h-(1)benzotieno-(3,2-e)-1,2-tiazin-1,1-dioksyder
GB1244682A (en) Anti-viral agents
ES8604550A1 (es) Procedimiento de preparacion de acidos dihidro-5,6-4h-ciclo-penta(b)tiofencarboxilicos-6
IL95377A0 (en) Therapeutic agent for the treatment of peptic ulcer disease containing xanthine derivatives and some novel compounds of this type
GB1512179A (en) Thionobenzenephosphonic acid 0,0-diesters and their use as insecticides and acaricides
DE3866729D1 (de) 4-chloroxazol-derivate, verfahren zu ihrer herstellung und ihre verwendung.
DK218989A (da) Pyridinderivater