ATE107280T1 - Carbamoyl-2-pyrrolidinonverbindungen. - Google Patents

Carbamoyl-2-pyrrolidinonverbindungen.

Info

Publication number
ATE107280T1
ATE107280T1 AT89904600T AT89904600T ATE107280T1 AT E107280 T1 ATE107280 T1 AT E107280T1 AT 89904600 T AT89904600 T AT 89904600T AT 89904600 T AT89904600 T AT 89904600T AT E107280 T1 ATE107280 T1 AT E107280T1
Authority
AT
Austria
Prior art keywords
substd
opt
phenyl
tetrahydronaphthyl
thiazolyl
Prior art date
Application number
AT89904600T
Other languages
English (en)
Inventor
Makoto Kajitani
Etsuo Hasegawa
Akihiro Kawaguchi
Junji Yamamoto
Katsuo Toide
Takaji Honna
Mitsugi Yasumoto
Nobuo Kasahara
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP63093967A external-priority patent/JP2611802B2/ja
Priority claimed from JP63093968A external-priority patent/JP2611803B2/ja
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE107280T1 publication Critical patent/ATE107280T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT89904600T 1988-04-15 1989-04-12 Carbamoyl-2-pyrrolidinonverbindungen. ATE107280T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63093967A JP2611802B2 (ja) 1988-04-15 1988-04-15 カルバモイル−２−ピロリジノン化合物
JP63093968A JP2611803B2 (ja) 1988-04-15 1988-04-15 脳機能改善剤及び脳代謝賦活・保護剤

Publications (1)

Publication Number Publication Date
ATE107280T1 true ATE107280T1 (de) 1994-07-15

Family

ID=26435227

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89904600T ATE107280T1 (de) 1988-04-15 1989-04-12 Carbamoyl-2-pyrrolidinonverbindungen.

Country Status (7)

Country Link
US (2) US5229402A (de)
EP (1) EP0373226B1 (de)
KR (1) KR910009934B1 (de)
AT (1) ATE107280T1 (de)
AU (1) AU615544B2 (de)
DE (1) DE68916198T2 (de)
WO (1) WO1989009767A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE107280T1 (de) * 1988-04-15 1994-07-15 Taiho Pharmaceutical Co Ltd Carbamoyl-2-pyrrolidinonverbindungen.
FR2647785B1 (fr) * 1989-05-31 1991-09-06 Adir Nouveaux derives de la pyrrolidone, leur procede de preparation et les compositions pharmaceutiques les renfermant
JP2803882B2 (ja) * 1990-02-20 1998-09-24 日清製粉株式会社 １―フエノキシカルボニル―２―ピロリジノン誘導体
IT1242043B (it) * 1990-12-21 1994-02-02 Sigma Tau Ind Farmaceuti Derivati della 1,2,3,4,-tetraidronaftilammina ad attivita' nootropica e composizioni farmaceutiche che li contengono.
JP3719612B2 (ja) * 1993-06-14 2005-11-24 塩野義製薬株式会社 ヘテロ環を含有する尿素誘導体
JP5037767B2 (ja) * 2001-09-19 2012-10-03 キヤノン株式会社 振動型アクチュエータの制御装置
TW200519106A (en) 2003-05-02 2005-06-16 Novartis Ag Organic compounds
US7021858B2 (en) * 2004-02-12 2006-04-04 Temenuzhka Bencheva Beloreshka Double joints pavement system
CA2710122A1 (en) 2007-12-20 2009-07-02 Novartis Ag Thiazole derivatives used as pi 3 kinase inhibitors
UA104147C2 (uk) 2008-09-10 2014-01-10 Новартис Аг Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
US8293753B2 (en) 2009-07-02 2012-10-23 Novartis Ag Substituted 2-carboxamide cycloamino ureas

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1593586A (de) * 1967-10-17 1970-06-01
FR2018820A1 (fr) * 1968-09-25 1970-06-26 Basf Ag Urees substituees
JPS5225026A (en) * 1975-08-15 1977-02-24 Rikagaku Kenkyusho Germicide for agriculture and gardening
JPS5822111B2 (ja) * 1977-10-29 1983-05-06 協和醗酵工業株式会社 柑橘類果実の改質剤
JPS55153763A (en) * 1979-05-21 1980-11-29 Kyowa Hakko Kogyo Co Ltd Modifier for citrus fruits
CA1305148C (en) * 1987-08-19 1992-07-14 Hiromu Matsumura Carbamoylpyrrolidone derivatives and drugs for senile dementia
ATE107280T1 (de) * 1988-04-15 1994-07-15 Taiho Pharmaceutical Co Ltd Carbamoyl-2-pyrrolidinonverbindungen.
JPH05225026A (ja) * 1992-02-10 1993-09-03 Chubu Nippon Denki Software Kk 障害復旧方式

Also Published As

Publication number Publication date
AU3421589A (en) 1989-11-03
AU615544B2 (en) 1991-10-03
EP0373226B1 (de) 1994-06-15
US5229402A (en) 1993-07-20
US5447944A (en) 1995-09-05
WO1989009767A1 (en) 1989-10-19
EP0373226A1 (de) 1990-06-20
KR910009934B1 (ko) 1991-12-06
DE68916198D1 (de) 1994-07-21
KR900700450A (ko) 1990-08-13
EP0373226A4 (en) 1990-09-26
DE68916198T2 (de) 1994-09-22

Similar Documents

Publication Publication Date Title
PL216409A1 (de)
DE68916198D1 (de) Carbamoyl-2-Pyrrolidinonverbindungen.
DE3873007D1 (de) Kathartica.
JPS5424882A (en) Novel heterocyclic compounds and their preparation
JPS5436235A (en) 4-n-alkyl-delta'-cyclohexene-1-carboxylic acids
ATE136307T1 (de) Trazodone alkyl derivate mit zns wirkung
DK0413278T3 (da) Anvendelse af xanthinderivater mod mavesår
JPS53141336A (en) Preparation of monoazo dyes
JPS5414956A (en) Novel 3-amino-4-homoisotwistan derivative
DE3773595D1 (en) Furan- und thiophencarbonsaeurepropargylester.
JPS5293770A (en) Benzotriazoles
JPS51123823A (en) A barbituric acid insecticide and tickicide
JPS52131589A (en) Trimethoxybenzylpiperazinoethanol derivatives
JPS5231071A (en) 5-benzyl-2-oxazolidone derivatives
JPS525730A (en) Process for preparation of 1,3,5-tri-substituted derivatives
JPS5414971A (en) Novel diaminotriazole derivative and its preparation
ZA871994B (en) Pyridine derivatives
JPS5283559A (en) 2-substituted-1,3-diazacycloalkanes
FR2251267A1 (en) Herbicidal compsns. - contg. 3-cyclo hexyl-5,6-trimethylene -uracil and 3-carbamoyloxy-acylanilines
JPS53149932A (en) 2-(3-alkylnitrosoureido)-hexapyranoside derivatives
JPS5283672A (en) Novel 2-amino-1,4-dihydropyridine derivatives
ES8403467A1 (es) Procedimiento para la obtencion de derivados de oximino-cian-acetamida sustituidos por azol.
JPS5283533A (en) 6-substituted naphtehalene-2-oxyalkylamines
JPS53147017A (en) Compound of acylketene-s.n-acetal and its preparation
JPS5242893A (en) Preparation of thiohydantoins

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee