ATE107280T1 - Carbamoyl-2-pyrrolidinonverbindungen. - Google Patents
Carbamoyl-2-pyrrolidinonverbindungen.Info
- Publication number
- ATE107280T1 ATE107280T1 AT89904600T AT89904600T ATE107280T1 AT E107280 T1 ATE107280 T1 AT E107280T1 AT 89904600 T AT89904600 T AT 89904600T AT 89904600 T AT89904600 T AT 89904600T AT E107280 T1 ATE107280 T1 AT E107280T1
- Authority
- AT
- Austria
- Prior art keywords
- substd
- opt
- phenyl
- tetrahydronaphthyl
- thiazolyl
- Prior art date
Links
- XYVMBSCIEDOIJQ-UHFFFAOYSA-N Squamolone Chemical class NC(=O)N1CCCC1=O XYVMBSCIEDOIJQ-UHFFFAOYSA-N 0.000 title abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 abstract 4
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 3
- 125000004076 pyridyl group Chemical group 0.000 abstract 3
- 125000000335 thiazolyl group Chemical group 0.000 abstract 3
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004970 halomethyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000002664 nootropic agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63093967A JP2611802B2 (ja) | 1988-04-15 | 1988-04-15 | カルバモイル−２−ピロリジノン化合物 |
| JP63093968A JP2611803B2 (ja) | 1988-04-15 | 1988-04-15 | 脳機能改善剤及び脳代謝賦活・保護剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE107280T1 true ATE107280T1 (de) | 1994-07-15 |
Family
ID=26435227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89904600T ATE107280T1 (de) | 1988-04-15 | 1989-04-12 | Carbamoyl-2-pyrrolidinonverbindungen. |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5229402A (de) |
| EP (1) | EP0373226B1 (de) |
| KR (1) | KR910009934B1 (de) |
| AT (1) | ATE107280T1 (de) |
| AU (1) | AU615544B2 (de) |
| DE (1) | DE68916198T2 (de) |
| WO (1) | WO1989009767A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5229402A (en) * | 1988-04-15 | 1993-07-20 | Taiho Pharmaceutical Company, Ltd. | Carbamoyl-2-pyrrolidinone compounds |
| FR2647785B1 (fr) * | 1989-05-31 | 1991-09-06 | Adir | Nouveaux derives de la pyrrolidone, leur procede de preparation et les compositions pharmaceutiques les renfermant |
| JP2803882B2 (ja) * | 1990-02-20 | 1998-09-24 | 日清製粉株式会社 | １―フエノキシカルボニル―２―ピロリジノン誘導体 |
| IT1242043B (it) * | 1990-12-21 | 1994-02-02 | Sigma Tau Ind Farmaceuti | Derivati della 1,2,3,4,-tetraidronaftilammina ad attivita' nootropica e composizioni farmaceutiche che li contengono. |
| JP3719612B2 (ja) * | 1993-06-14 | 2005-11-24 | 塩野義製薬株式会社 | ヘテロ環を含有する尿素誘導体 |
| JP5037767B2 (ja) * | 2001-09-19 | 2012-10-03 | キヤノン株式会社 | 振動型アクチュエータの制御装置 |
| TW200519106A (en) | 2003-05-02 | 2005-06-16 | Novartis Ag | Organic compounds |
| US7021858B2 (en) * | 2004-02-12 | 2006-04-04 | Temenuzhka Bencheva Beloreshka | Double joints pavement system |
| BRPI0820722A2 (pt) | 2007-12-20 | 2015-06-16 | Novartis Ag | Derivados de tiazol usados como inibidores de pi 3 cinases |
| UA104147C2 (uk) | 2008-09-10 | 2014-01-10 | Новартис Аг | Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань |
| US8293753B2 (en) | 2009-07-02 | 2012-10-23 | Novartis Ag | Substituted 2-carboxamide cycloamino ureas |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1593586A (de) * | 1967-10-17 | 1970-06-01 | ||
| FR2018820A1 (fr) * | 1968-09-25 | 1970-06-26 | Basf Ag | Urees substituees |
| JPS5225026A (en) * | 1975-08-15 | 1977-02-24 | Rikagaku Kenkyusho | Germicide for agriculture and gardening |
| JPS5822111B2 (ja) * | 1977-10-29 | 1983-05-06 | 協和醗酵工業株式会社 | 柑橘類果実の改質剤 |
| JPS55153763A (en) * | 1979-05-21 | 1980-11-29 | Kyowa Hakko Kogyo Co Ltd | Modifier for citrus fruits |
| CA1305148C (en) * | 1987-08-19 | 1992-07-14 | Hiromu Matsumura | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
| US5229402A (en) * | 1988-04-15 | 1993-07-20 | Taiho Pharmaceutical Company, Ltd. | Carbamoyl-2-pyrrolidinone compounds |
| JPH05225026A (ja) * | 1992-02-10 | 1993-09-03 | Chubu Nippon Denki Software Kk | 障害復旧方式 |
-
1989
- 1989-04-12 US US07/449,923 patent/US5229402A/en not_active Expired - Fee Related
- 1989-04-12 AU AU34215/89A patent/AU615544B2/en not_active Ceased
- 1989-04-12 WO PCT/JP1989/000401 patent/WO1989009767A1/ja not_active Ceased
- 1989-04-12 KR KR1019890702310A patent/KR910009934B1/ko not_active Expired
- 1989-04-12 AT AT89904600T patent/ATE107280T1/de not_active IP Right Cessation
- 1989-04-12 DE DE68916198T patent/DE68916198T2/de not_active Expired - Fee Related
- 1989-04-12 EP EP89904600A patent/EP0373226B1/de not_active Expired - Lifetime
-
1994
- 1994-03-22 US US08/216,244 patent/US5447944A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR910009934B1 (ko) | 1991-12-06 |
| EP0373226A4 (en) | 1990-09-26 |
| WO1989009767A1 (fr) | 1989-10-19 |
| US5229402A (en) | 1993-07-20 |
| AU3421589A (en) | 1989-11-03 |
| DE68916198T2 (de) | 1994-09-22 |
| KR900700450A (ko) | 1990-08-13 |
| EP0373226B1 (de) | 1994-06-15 |
| DE68916198D1 (de) | 1994-07-21 |
| AU615544B2 (en) | 1991-10-03 |
| EP0373226A1 (de) | 1990-06-20 |
| US5447944A (en) | 1995-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |