ES8604179A1 - Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos - Google Patents
Procedimiento para la preparacion de nuevos derivados tiazo-lidinicosInfo
- Publication number
- ES8604179A1 ES8604179A1 ES544286A ES544286A ES8604179A1 ES 8604179 A1 ES8604179 A1 ES 8604179A1 ES 544286 A ES544286 A ES 544286A ES 544286 A ES544286 A ES 544286A ES 8604179 A1 ES8604179 A1 ES 8604179A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical compositions
- thiazolidine derivatives
- thiazolidine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS TIZAOLIDINICOS. CONSISTE EN N-ALQUILAR A UN DERIVADO TIZAOLIDINICO 2-SUSTITUIDO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN METANOL, ETANOL, ETER, EN PRESENCIA DE UN AGLUTINANTE DE ACIDOS COMO HIDROXIDOS METALICOS ALCALINOS, CARBONATOS, ALCOHOLATOS Y A LA TEMPERATURA DE EBULLICION DEL DISOLVENTE, PARA OBTENER DERIVADOS TIAZOLIDINICOS DE FORMULA (I). SIENDO: AR UN GRUPO 2-FURILO O UN GRUPO NAFTILO O PIRIDILO SUSTITUIDO POR UNO MAS ATOMOS DE HAL, Y OTROS; X, HAL O UN GRUPO ESTER REACTIVO; Y, N O CH Y Z CIANO O CARBAMOILO. SE UTILIZAN COMO AGENTES ANTI-ULCEROSOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU83888A HU188852B (en) | 1983-03-16 | 1983-03-16 | Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8604179A1 true ES8604179A1 (es) | 1986-01-16 |
ES544286A0 ES544286A0 (es) | 1986-01-16 |
Family
ID=10951891
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES530738A Granted ES530738A0 (es) | 1983-03-16 | 1984-03-16 | Procedimiento para la preparacion de nuevos derivados tiazolidinicos |
ES544286A Expired ES8604179A1 (es) | 1983-03-16 | 1985-06-17 | Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES530738A Granted ES530738A0 (es) | 1983-03-16 | 1984-03-16 | Procedimiento para la preparacion de nuevos derivados tiazolidinicos |
Country Status (32)
Country | Link |
---|---|
US (1) | US4616025A (es) |
JP (1) | JPS59196877A (es) |
KR (1) | KR840008001A (es) |
AT (1) | AT383596B (es) |
AU (1) | AU559753B2 (es) |
BE (1) | BE899132A (es) |
CA (1) | CA1273933A (es) |
CH (1) | CH660592A5 (es) |
CS (1) | CS241074B2 (es) |
DD (1) | DD216929A5 (es) |
DE (1) | DE3409801A1 (es) |
DK (1) | DK143284A (es) |
ES (2) | ES530738A0 (es) |
FI (1) | FI79843C (es) |
FR (1) | FR2542740B1 (es) |
GB (1) | GB2140412B (es) |
GR (1) | GR81883B (es) |
HU (1) | HU188852B (es) |
IE (1) | IE57101B1 (es) |
IL (1) | IL71249A (es) |
IN (1) | IN157738B (es) |
IT (1) | IT1196048B (es) |
LU (1) | LU85248A1 (es) |
NL (1) | NL8400817A (es) |
NO (1) | NO162858C (es) |
NZ (1) | NZ207516A (es) |
PL (2) | PL142909B1 (es) |
PT (1) | PT78260B (es) |
SE (1) | SE455945B (es) |
SU (2) | SU1240355A3 (es) |
YU (1) | YU47384A (es) |
ZA (1) | ZA841938B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6051184A (ja) * | 1983-08-30 | 1985-03-22 | Fujimoto Seiyaku Kk | Ν−シアノイミノチアゾリジン誘導体およびその製造法 |
DE3681465D1 (es) * | 1985-02-04 | 1991-10-24 | Nihon Bayer Agrochem K.K., Tokio/Tokyo, Jp | |
US5001138B1 (en) * | 1985-02-04 | 1998-01-20 | Bayer Agrochem Kk | Heterocyclic compounds |
US5204360A (en) * | 1985-02-04 | 1993-04-20 | Nihon Bayer Agrochem K.K. | Heterocyclic compounds |
JPH066585B2 (ja) * | 1985-02-04 | 1994-01-26 | 日本バイエルアグロケム株式会社 | ニトロメチレン誘導体、その製法及び殺虫剤 |
JPH0730070B2 (ja) * | 1985-10-03 | 1995-04-05 | 日本バイエルアグロケム株式会社 | 新規複素環式化合物 |
JPH0649699B2 (ja) * | 1985-02-04 | 1994-06-29 | 日本バイエルアグロケム株式会社 | ニトロメチレン誘導体、その製法及び殺虫剤 |
USRE39130E1 (en) | 1986-03-07 | 2006-06-13 | Bayer Cropscience K.K. | Heterocyclic compounds |
JPH0717621B2 (ja) * | 1986-03-07 | 1995-03-01 | 日本バイエルアグロケム株式会社 | 新規ヘテロ環式化合物 |
JP2607369B2 (ja) * | 1987-02-20 | 1997-05-07 | 興和株式会社 | 新規な複素環化合物 |
US5122522A (en) * | 1989-06-21 | 1992-06-16 | The Trustees Of The University Of Pennsylvania | Treatment and control of ocular development |
ATE203666T1 (de) * | 1989-06-21 | 2001-08-15 | Univ Pennsylvania | Verwendung eines muskarinantagonists zur herstellung eines medikaments für die behandlung und regulierung der augenentwicklung |
HU207047B (en) * | 1989-11-07 | 1993-03-01 | Richter Gedeon Vegyeszet | Process for producing new pyridine derivatives and pharmaceutical copositions comprising same |
CA2063865A1 (en) * | 1992-03-24 | 1993-09-25 | Karoly Lempert | 2-(substituted imino)-thiazolidines and process for the preparation thereof |
JP2721805B2 (ja) * | 1994-07-22 | 1998-03-04 | 日本バイエルアグロケム株式会社 | 新規ヘテロ環式化合物 |
DE4427569A1 (de) * | 1994-08-04 | 1996-02-08 | Bayer Ag | Verfahren zur Herstellung von Cyanimino-1,3-thiazolidin |
DE4427539A1 (de) * | 1994-08-04 | 1996-02-08 | Sueddeutsche Kalkstickstoff | Verfahren zur Herstellung von 2-Cyaniminothiazolidin |
DE19904310A1 (de) * | 1999-01-28 | 2000-08-03 | Bayer Ag | Verfahren zur Herstellung heterocyclischer Verbindungen |
CN1198803C (zh) * | 1999-03-05 | 2005-04-27 | 第一三得利制药株式会社 | 具有激活烟碱性乙酰胆碱α4β2受体作用的杂环化合物 |
NZ529615A (en) * | 2001-05-25 | 2005-07-29 | Valley Forge Pharmaceuticals | Pirenzepine ophthalmic gel |
US7767701B2 (en) * | 2002-11-22 | 2010-08-03 | Glaxosmithkline Llc | Chemical compounds |
AU2004228069B2 (en) * | 2003-04-07 | 2011-09-08 | Cortical Pty Ltd | Novel methods for the treatment of inflammatory diseases |
CA2729191A1 (en) * | 2008-07-01 | 2010-01-07 | Gifu University | Novel imino derivatives, methods for producing the same and insecticides containing the same |
DK2751100T3 (en) * | 2011-09-02 | 2016-01-18 | Bayer Ip Gmbh | METHOD FOR PREPARING [3 - [(6-CHLOR-3-PYRIDINYL) METHYL] -2-THIAZOLIDINYLIDE] CYANAMIDE |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3264316A (en) * | 1963-09-18 | 1966-08-02 | Res Lab Dr C Janssen N V | Certain 2-acylimino-3-substitutedthiazoline-4 compounds |
DE2205745A1 (de) * | 1972-02-08 | 1973-08-23 | Thomae Gmbh Dr K | Neue durch den n-cyaniminorest substituierten heterocyclen und verfahren zu ihrer herstellung |
US4006156A (en) * | 1975-06-27 | 1977-02-01 | Shell Oil Company | 3-Alkyl-2-(nitromethylene) thiazolidine |
NL7704322A (nl) * | 1976-05-03 | 1977-11-07 | Merck & Co Inc | Werkwijze voor het bereiden van 2-iminothiazo- lidinen en -thiazolinen. |
JPS57171986A (en) * | 1981-04-14 | 1982-10-22 | Taiho Yakuhin Kogyo Kk | Heterocylic ring compound containing sulfur |
JPS5823682A (ja) * | 1981-08-03 | 1983-02-12 | Santen Pharmaceut Co Ltd | 複素五員環化合物 |
DE3133918A1 (de) * | 1981-08-27 | 1983-03-17 | Bayer Ag, 5090 Leverkusen | 2-arylhydrazino-2-thiazoline, acylderivate derselben, 2-arylazo-2-thiazoline, herstellungsverfahren und ihre verwendung zur bekaempfung von ekto- und endoparasiten |
JPS58222886A (ja) * | 1982-06-19 | 1983-12-24 | Ricoh Co Ltd | 感熱記録シ−ト |
JPS5933267A (ja) * | 1982-08-19 | 1984-02-23 | Fujimoto Seiyaku Kk | グアニジン誘導体およびその製造法 |
-
1983
- 1983-03-16 HU HU83888A patent/HU188852B/hu not_active IP Right Cessation
-
1984
- 1984-02-29 DK DK143284A patent/DK143284A/da not_active Application Discontinuation
- 1984-03-12 CH CH1211/84A patent/CH660592A5/de not_active IP Right Cessation
- 1984-03-12 BE BE1/10980A patent/BE899132A/fr not_active IP Right Cessation
- 1984-03-13 PL PL1984252129A patent/PL142909B1/pl unknown
- 1984-03-14 LU LU85248A patent/LU85248A1/fr unknown
- 1984-03-15 IN IN186/CAL/84A patent/IN157738B/en unknown
- 1984-03-15 ZA ZA841938A patent/ZA841938B/xx unknown
- 1984-03-15 CA CA000449688A patent/CA1273933A/en not_active Expired - Fee Related
- 1984-03-15 NL NL8400817A patent/NL8400817A/nl not_active Application Discontinuation
- 1984-03-15 IT IT20057/84A patent/IT1196048B/it active
- 1984-03-15 NZ NZ207516A patent/NZ207516A/en unknown
- 1984-03-15 PT PT78260A patent/PT78260B/pt not_active IP Right Cessation
- 1984-03-15 GR GR74119A patent/GR81883B/el unknown
- 1984-03-15 IE IE655/84A patent/IE57101B1/en unknown
- 1984-03-15 AT AT0088284A patent/AT383596B/de not_active IP Right Cessation
- 1984-03-15 CS CS841885A patent/CS241074B2/cs unknown
- 1984-03-15 IL IL71249A patent/IL71249A/xx unknown
- 1984-03-15 SE SE8401463A patent/SE455945B/sv not_active IP Right Cessation
- 1984-03-15 JP JP59048270A patent/JPS59196877A/ja active Pending
- 1984-03-15 NO NO841002A patent/NO162858C/no unknown
- 1984-03-15 PL PL1984246683A patent/PL142749B1/pl unknown
- 1984-03-15 FR FR8403985A patent/FR2542740B1/fr not_active Expired
- 1984-03-15 DD DD84260939A patent/DD216929A5/de not_active IP Right Cessation
- 1984-03-15 GB GB08406790A patent/GB2140412B/en not_active Expired
- 1984-03-16 DE DE3409801A patent/DE3409801A1/de not_active Withdrawn
- 1984-03-16 SU SU843713458A patent/SU1240355A3/ru active
- 1984-03-16 US US06/590,486 patent/US4616025A/en not_active Expired - Fee Related
- 1984-03-16 AU AU25833/84A patent/AU559753B2/en not_active Ceased
- 1984-03-16 FI FI841066A patent/FI79843C/fi not_active IP Right Cessation
- 1984-03-16 KR KR1019840001360A patent/KR840008001A/ko not_active Application Discontinuation
- 1984-03-16 ES ES530738A patent/ES530738A0/es active Granted
- 1984-03-16 YU YU00473/84A patent/YU47384A/xx unknown
- 1984-10-17 SU SU843799805A patent/SU1240356A3/ru active
-
1985
- 1985-06-17 ES ES544286A patent/ES8604179A1/es not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960401 |