DD216459A5 - Verfahren zur herstellung von nizatidin - Google Patents

Verfahren zur herstellung von nizatidin Download PDF

Info

Publication number
DD216459A5
DD216459A5 DD84259880A DD25988084A DD216459A5 DD 216459 A5 DD216459 A5 DD 216459A5 DD 84259880 A DD84259880 A DD 84259880A DD 25988084 A DD25988084 A DD 25988084A DD 216459 A5 DD216459 A5 DD 216459A5
Authority
DD
German Democratic Republic
Prior art keywords
acid
methyl
product
reaction
aqueous
Prior art date
Application number
DD84259880A
Other languages
German (de)
English (en)
Inventor
Charles W Ryan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23843341&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD216459(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD216459A5 publication Critical patent/DD216459A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Credit Cards Or The Like (AREA)
DD84259880A 1983-02-07 1984-02-06 Verfahren zur herstellung von nizatidin DD216459A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46429683A 1983-02-07 1983-02-07

Publications (1)

Publication Number Publication Date
DD216459A5 true DD216459A5 (de) 1984-12-12

Family

ID=23843341

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84259880A DD216459A5 (de) 1983-02-07 1984-02-06 Verfahren zur herstellung von nizatidin

Country Status (27)

Country Link
EP (1) EP0116452B1 (pt)
JP (1) JPS59152378A (pt)
KR (1) KR860000767B1 (pt)
AT (1) ATE84530T1 (pt)
AU (1) AU559639B2 (pt)
BG (1) BG45216A3 (pt)
CA (1) CA1221369A (pt)
CS (1) CS240994B2 (pt)
DD (1) DD216459A5 (pt)
DE (1) DE3486032T2 (pt)
DK (2) DK164501C (pt)
EG (1) EG17702A (pt)
ES (1) ES8601941A1 (pt)
FI (1) FI840474A (pt)
GB (1) GB2134521B (pt)
GR (1) GR81755B (pt)
HU (2) HU190527B (pt)
IE (1) IE56763B1 (pt)
IL (1) IL70880A (pt)
NZ (1) NZ207046A (pt)
PH (1) PH19941A (pt)
PL (1) PL138793B1 (pt)
PT (1) PT78063A (pt)
RO (1) RO87706A (pt)
SU (1) SU1303028A3 (pt)
UA (1) UA6020A1 (pt)
ZA (1) ZA84869B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1277325C (en) * 1985-12-18 1990-12-04 Bruce A. Slomski Synthesis of nizatidine
ES2038922B1 (es) * 1991-12-30 1994-04-16 Fermentaciones Y Sintesis Espa Procedimiento para la obtencion de nizatidina.
US5470865A (en) * 1994-08-30 1995-11-28 Eli Lilly And Company Pharmaceutical composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
DE3486032T2 (de) 1993-05-19
DK164501C (da) 1992-11-23
JPH0576473B2 (pt) 1993-10-22
DK164906B (da) 1992-09-07
EP0116452A2 (en) 1984-08-22
ATE84530T1 (de) 1993-01-15
FI840474A0 (fi) 1984-02-06
ES529492A0 (es) 1985-11-01
DK164501B (da) 1992-07-06
GB2134521B (en) 1986-10-01
KR840007591A (ko) 1984-12-08
CS240994B2 (en) 1986-03-13
GB2134521A (en) 1984-08-15
HU194198B (en) 1988-01-28
HU190527B (en) 1986-09-29
NZ207046A (en) 1986-06-11
GB8403109D0 (en) 1984-03-07
PL138793B1 (en) 1986-11-29
DK51984D0 (da) 1984-02-06
FI840474A (fi) 1984-08-08
AU2421584A (en) 1984-08-16
RO87706B (ro) 1985-10-01
GR81755B (pt) 1984-12-12
ZA84869B (en) 1985-09-25
EP0116452B1 (en) 1993-01-13
IE840274L (en) 1984-08-07
DK164906C (da) 1993-01-25
IE56763B1 (en) 1991-12-04
DK51984A (da) 1984-08-08
JPS59152378A (ja) 1984-08-31
DK21292A (da) 1992-02-19
CA1221369A (en) 1987-05-05
RO87706A (ro) 1985-10-31
EG17702A (en) 1991-03-30
UA6020A1 (uk) 1994-12-29
BG45216A3 (bg) 1989-04-14
PT78063A (en) 1984-03-01
PH19941A (en) 1986-08-14
KR860000767B1 (ko) 1986-06-23
IL70880A (en) 1987-01-30
EP0116452A3 (en) 1987-04-29
ES8601941A1 (es) 1985-11-01
DE3486032D1 (de) 1993-02-25
IL70880A0 (en) 1984-05-31
SU1303028A3 (ru) 1987-04-07
AU559639B2 (en) 1987-03-19
CS81284A2 (en) 1985-06-13
PL246097A1 (en) 1985-06-04
DK21292D0 (da) 1992-02-19

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Legal Events

Date Code Title Description
IF04 In force in the year 2004

Expiry date: 20040207