DE3486032D1 - Synthese von nizatidin. - Google Patents

Synthese von nizatidin.

Info

Publication number
DE3486032D1
DE3486032D1 DE8484300720T DE3486032T DE3486032D1 DE 3486032 D1 DE3486032 D1 DE 3486032D1 DE 8484300720 T DE8484300720 T DE 8484300720T DE 3486032 T DE3486032 T DE 3486032T DE 3486032 D1 DE3486032 D1 DE 3486032D1
Authority
DE
Germany
Prior art keywords
nizatidin
synthesis
methyl
ylmethylthio
isothiourea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484300720T
Other languages
English (en)
Other versions
DE3486032T2 (de
Inventor
Charles Wilbur Ryan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23843341&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3486032(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE3486032D1 publication Critical patent/DE3486032D1/de
Application granted granted Critical
Publication of DE3486032T2 publication Critical patent/DE3486032T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
DE8484300720T 1983-02-07 1984-02-06 Synthese von nizatidin. Expired - Lifetime DE3486032T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46429683A 1983-02-07 1983-02-07

Publications (2)

Publication Number Publication Date
DE3486032D1 true DE3486032D1 (de) 1993-02-25
DE3486032T2 DE3486032T2 (de) 1993-05-19

Family

ID=23843341

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484300720T Expired - Lifetime DE3486032T2 (de) 1983-02-07 1984-02-06 Synthese von nizatidin.

Country Status (27)

Country Link
EP (1) EP0116452B1 (de)
JP (1) JPS59152378A (de)
KR (1) KR860000767B1 (de)
AT (1) ATE84530T1 (de)
AU (1) AU559639B2 (de)
BG (1) BG45216A3 (de)
CA (1) CA1221369A (de)
CS (1) CS240994B2 (de)
DD (1) DD216459A5 (de)
DE (1) DE3486032T2 (de)
DK (2) DK164501C (de)
EG (1) EG17702A (de)
ES (1) ES8601941A1 (de)
FI (1) FI840474A (de)
GB (1) GB2134521B (de)
GR (1) GR81755B (de)
HU (2) HU190527B (de)
IE (1) IE56763B1 (de)
IL (1) IL70880A (de)
NZ (1) NZ207046A (de)
PH (1) PH19941A (de)
PL (1) PL138793B1 (de)
PT (1) PT78063A (de)
RO (1) RO87706A (de)
SU (1) SU1303028A3 (de)
UA (1) UA6020A1 (de)
ZA (1) ZA84869B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0230127A1 (de) * 1985-12-18 1987-07-29 Eli Lilly And Company Verfahren zur Herstellung von Nizatidin
ES2038922B1 (es) * 1991-12-30 1994-04-16 Fermentaciones Y Sintesis Espa Procedimiento para la obtencion de nizatidina.
US5470865A (en) * 1994-08-30 1995-11-28 Eli Lilly And Company Pharmaceutical composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
IE840274L (en) 1984-08-07
ES529492A0 (es) 1985-11-01
JPS59152378A (ja) 1984-08-31
DK164906C (da) 1993-01-25
DK51984D0 (da) 1984-02-06
JPH0576473B2 (de) 1993-10-22
AU559639B2 (en) 1987-03-19
GB2134521B (en) 1986-10-01
HU194198B (en) 1988-01-28
KR840007591A (ko) 1984-12-08
CS240994B2 (en) 1986-03-13
DK21292A (da) 1992-02-19
GB8403109D0 (en) 1984-03-07
DK164501C (da) 1992-11-23
DD216459A5 (de) 1984-12-12
ES8601941A1 (es) 1985-11-01
EP0116452A3 (en) 1987-04-29
DK164501B (da) 1992-07-06
IL70880A0 (en) 1984-05-31
SU1303028A3 (ru) 1987-04-07
DK51984A (da) 1984-08-08
ATE84530T1 (de) 1993-01-15
NZ207046A (en) 1986-06-11
PT78063A (en) 1984-03-01
EP0116452B1 (de) 1993-01-13
EP0116452A2 (de) 1984-08-22
FI840474A (fi) 1984-08-08
HU190527B (en) 1986-09-29
AU2421584A (en) 1984-08-16
IE56763B1 (en) 1991-12-04
ZA84869B (en) 1985-09-25
EG17702A (en) 1991-03-30
GB2134521A (en) 1984-08-15
CA1221369A (en) 1987-05-05
DK21292D0 (da) 1992-02-19
PL246097A1 (en) 1985-06-04
PH19941A (en) 1986-08-14
DK164906B (da) 1992-09-07
FI840474A0 (fi) 1984-02-06
BG45216A3 (de) 1989-04-14
IL70880A (en) 1987-01-30
KR860000767B1 (ko) 1986-06-23
UA6020A1 (uk) 1994-12-29
RO87706B (ro) 1985-10-01
CS81284A2 (en) 1985-06-13
PL138793B1 (en) 1986-11-29
GR81755B (de) 1984-12-12
RO87706A (ro) 1985-10-31
DE3486032T2 (de) 1993-05-19

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