DD215086A5 - Verfahren zur herstellung von 17,17-bis-(substituierten thio)-3-ketoandrostenen - Google Patents
Verfahren zur herstellung von 17,17-bis-(substituierten thio)-3-ketoandrostenen Download PDFInfo
- Publication number
- DD215086A5 DD215086A5 DD82257409A DD25740982A DD215086A5 DD 215086 A5 DD215086 A5 DD 215086A5 DD 82257409 A DD82257409 A DD 82257409A DD 25740982 A DD25740982 A DD 25740982A DD 215086 A5 DD215086 A5 DD 215086A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- chloroform
- mixture
- fluoro
- bis
- item
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/294,680 US4361559A (en) | 1981-08-20 | 1981-08-20 | Antiinflammatory 17,17-bis (substituted thio) androstenes |
Publications (1)
Publication Number | Publication Date |
---|---|
DD215086A5 true DD215086A5 (de) | 1984-10-31 |
Family
ID=23134474
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD82257409A DD215086A5 (de) | 1981-08-20 | 1982-08-20 | Verfahren zur herstellung von 17,17-bis-(substituierten thio)-3-ketoandrostenen |
DD82242677A DD211567A5 (de) | 1981-08-20 | 1982-08-20 | Verfahren zur herstellung von 17,17-bis-(substituierten thio)-3-ketoandrostenen |
DD82257403A DD215556A5 (de) | 1981-08-20 | 1982-08-20 | Verfahren zur herstellung von 17,17-bis-(substituierten thio)-3-ketoandrostenen |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD82242677A DD211567A5 (de) | 1981-08-20 | 1982-08-20 | Verfahren zur herstellung von 17,17-bis-(substituierten thio)-3-ketoandrostenen |
DD82257403A DD215556A5 (de) | 1981-08-20 | 1982-08-20 | Verfahren zur herstellung von 17,17-bis-(substituierten thio)-3-ketoandrostenen |
Country Status (24)
Country | Link |
---|---|
US (1) | US4361559A (da) |
EP (1) | EP0073026B1 (da) |
JP (1) | JPS5841900A (da) |
KR (1) | KR890000678B1 (da) |
AT (1) | ATE18671T1 (da) |
AU (1) | AU564228B2 (da) |
CA (1) | CA1213270A (da) |
CS (1) | CS235959B2 (da) |
DD (3) | DD215086A5 (da) |
DE (1) | DE3269987D1 (da) |
DK (1) | DK165838C (da) |
ES (3) | ES8308336A1 (da) |
FI (1) | FI78916C (da) |
GR (1) | GR76251B (da) |
HU (1) | HU187783B (da) |
IE (1) | IE53732B1 (da) |
IL (1) | IL66564A (da) |
NO (1) | NO159601C (da) |
NZ (1) | NZ201343A (da) |
PH (2) | PH18594A (da) |
PL (2) | PL141303B1 (da) |
PT (1) | PT75442B (da) |
SU (1) | SU1189353A3 (da) |
ZA (1) | ZA825260B (da) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4447363A (en) * | 1982-07-07 | 1984-05-08 | E. R. Squibb & Sons, Inc. | Androstene-17-dithioketals |
US4435326A (en) * | 1982-09-09 | 1984-03-06 | E. R. Squibb & Sons, Inc. | Intermediates useful in the preparation of 17,17-bis(substituted thio)androstenes |
US4420428A (en) * | 1982-12-27 | 1983-12-13 | E. R. Squibb & Sons, Inc. | 16-Ketoandrostene-17-dithioketals |
US4427592A (en) * | 1983-01-31 | 1984-01-24 | E. R. Squibb & Sons, Inc. | Androstene-17-dithioketals |
US4481144A (en) * | 1984-02-03 | 1984-11-06 | E. R. Squibb & Sons, Inc. | 17-Substituted thia-17-alkyl(or alkenyl or alkynyl)androstenes |
US4499021A (en) * | 1984-04-12 | 1985-02-12 | E. R. Squibb & Sons, Inc. | 17β(Substituted thio)-16-ketoandrostene-17α..-carboxylic acid derivatives |
US4529548A (en) * | 1984-05-07 | 1985-07-16 | E. R. Squibb & Sons, Inc. | 17β-(substituted thio)androstenes |
US4528138A (en) * | 1984-06-20 | 1985-07-09 | E. R. Squibb & Sons, Inc. | 16-Keto-17-substituted thia-17-alkyl(or alkenyl or alkynyl) androstenes |
US4529547A (en) * | 1984-06-20 | 1985-07-16 | E.R. Squibb & Sons, Inc. | 17-(substituted thio)-17-(substituted dithio)androstenes |
US4891367A (en) * | 1987-04-22 | 1990-01-02 | Merrell Dow Pharmaceuticals Inc. | 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
US4868168A (en) * | 1987-11-13 | 1989-09-19 | E. R. Squibb & Sons, Inc. | Steroid ointment formulation |
US4868169A (en) * | 1987-11-13 | 1989-09-19 | E. R. Squibb & Sons, Inc. | Steroid cream formulation |
US5016635A (en) * | 1988-11-29 | 1991-05-21 | Sigmedics, Inc. Of Delaware | Control of FNS via pattern variations of response EMG |
US4883792A (en) * | 1989-01-17 | 1989-11-28 | Peter Timmins | Steroid cream formulation |
GB9103824D0 (en) * | 1991-02-23 | 1991-04-10 | Fisons Ag | Formulation |
IE922301A1 (en) * | 1991-07-25 | 1993-01-27 | Squibb & Sons Inc | Selective thioketalization process, process for preparing¹thioenol ethers from thioketals, and process for the¹preparation of thioketals |
DK0675897T3 (da) * | 1992-12-24 | 1998-01-26 | Rhone Poulenc Rorer Ltd | Nye steroider |
US5439901A (en) * | 1993-07-23 | 1995-08-08 | The Procter & Gamble Company | Cyproterone thiopivalate |
US5344651A (en) * | 1993-07-23 | 1994-09-06 | The Procter & Gamble Company | Cyproterone acetate thioacetate |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2840577A (en) * | 1956-12-21 | 1958-06-24 | Searle & Co | 17-thio derivatives of estratrien-3-ol and of estratetraen-3-ol |
US2949477A (en) * | 1959-03-04 | 1960-08-16 | Searle & Co | 1, 3, 17-triacetoxyestra-1, 3, 5(10), 16-tetraene and congeners |
US4094840A (en) * | 1977-05-12 | 1978-06-13 | E. R. Squibb & Sons, Inc. | 17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones |
US4091036A (en) * | 1977-05-12 | 1978-05-23 | E. R. Squibb & Sons, Inc. | 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives |
US4133811A (en) * | 1978-02-17 | 1979-01-09 | E. R. Squibb & Sons, Inc. | 13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes |
US4146538A (en) * | 1978-02-27 | 1979-03-27 | E. R. Squibb & Sons, Inc. | 17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones |
-
1981
- 1981-08-20 US US06/294,680 patent/US4361559A/en not_active Expired - Lifetime
-
1982
- 1982-07-19 CA CA000407557A patent/CA1213270A/en not_active Expired
- 1982-07-21 NZ NZ201343A patent/NZ201343A/en unknown
- 1982-07-22 AU AU86318/82A patent/AU564228B2/en not_active Ceased
- 1982-07-22 ZA ZA825260A patent/ZA825260B/xx unknown
- 1982-08-10 PH PH27702A patent/PH18594A/en unknown
- 1982-08-12 GR GR69029A patent/GR76251B/el unknown
- 1982-08-12 IE IE1951/82A patent/IE53732B1/en not_active IP Right Cessation
- 1982-08-17 PL PL1982237936A patent/PL141303B1/pl unknown
- 1982-08-17 PL PL24411382A patent/PL244113A1/xx unknown
- 1982-08-18 IL IL66564A patent/IL66564A/xx not_active IP Right Cessation
- 1982-08-18 HU HU822683A patent/HU187783B/hu not_active IP Right Cessation
- 1982-08-19 ES ES515110A patent/ES8308336A1/es not_active Expired
- 1982-08-19 FI FI822890A patent/FI78916C/fi not_active IP Right Cessation
- 1982-08-19 DE DE8282107589T patent/DE3269987D1/de not_active Expired
- 1982-08-19 JP JP57144576A patent/JPS5841900A/ja active Granted
- 1982-08-19 EP EP82107589A patent/EP0073026B1/en not_active Expired
- 1982-08-19 CS CS826085A patent/CS235959B2/cs unknown
- 1982-08-19 DK DK372982A patent/DK165838C/da not_active IP Right Cessation
- 1982-08-19 NO NO822823A patent/NO159601C/no unknown
- 1982-08-19 PT PT75442A patent/PT75442B/pt not_active IP Right Cessation
- 1982-08-19 AT AT82107589T patent/ATE18671T1/de not_active IP Right Cessation
- 1982-08-19 KR KR8203735A patent/KR890000678B1/ko active
- 1982-08-19 SU SU823480340A patent/SU1189353A3/ru active
- 1982-08-20 DD DD82257409A patent/DD215086A5/de not_active IP Right Cessation
- 1982-08-20 DD DD82242677A patent/DD211567A5/de not_active IP Right Cessation
- 1982-08-20 DD DD82257403A patent/DD215556A5/de not_active IP Right Cessation
-
1983
- 1983-04-29 ES ES521952A patent/ES521952A0/es active Granted
- 1983-04-29 ES ES521951A patent/ES8406505A1/es not_active Expired
-
1984
- 1984-06-29 PH PH30900A patent/PH19857A/en unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ENJ | Ceased due to non-payment of renewal fee |