PT75442B - Antiinflammatory 17, 17-bis(substituted thio) androstenes - Google Patents

Antiinflammatory 17, 17-bis(substituted thio) androstenes

Info

Publication number
PT75442B
PT75442B PT75442A PT7544282A PT75442B PT 75442 B PT75442 B PT 75442B PT 75442 A PT75442 A PT 75442A PT 7544282 A PT7544282 A PT 7544282A PT 75442 B PT75442 B PT 75442B
Authority
PT
Portugal
Prior art keywords
antiinflammatory
androstenes
bis
substituted thio
thio
Prior art date
Application number
PT75442A
Other languages
English (en)
Other versions
PT75442A (en
Inventor
Ravi K Varma
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of PT75442A publication Critical patent/PT75442A/pt
Publication of PT75442B publication Critical patent/PT75442B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
PT75442A 1981-08-20 1982-08-19 Antiinflammatory 17, 17-bis(substituted thio) androstenes PT75442B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/294,680 US4361559A (en) 1981-08-20 1981-08-20 Antiinflammatory 17,17-bis (substituted thio) androstenes

Publications (2)

Publication Number Publication Date
PT75442A PT75442A (en) 1982-09-01
PT75442B true PT75442B (en) 1985-01-04

Family

ID=23134474

Family Applications (1)

Application Number Title Priority Date Filing Date
PT75442A PT75442B (en) 1981-08-20 1982-08-19 Antiinflammatory 17, 17-bis(substituted thio) androstenes

Country Status (24)

Country Link
US (1) US4361559A (pt)
EP (1) EP0073026B1 (pt)
JP (1) JPS5841900A (pt)
KR (1) KR890000678B1 (pt)
AT (1) ATE18671T1 (pt)
AU (1) AU564228B2 (pt)
CA (1) CA1213270A (pt)
CS (1) CS235959B2 (pt)
DD (3) DD215556A5 (pt)
DE (1) DE3269987D1 (pt)
DK (1) DK165838C (pt)
ES (3) ES515110A0 (pt)
FI (1) FI78916C (pt)
GR (1) GR76251B (pt)
HU (1) HU187783B (pt)
IE (1) IE53732B1 (pt)
IL (1) IL66564A (pt)
NO (1) NO159601C (pt)
NZ (1) NZ201343A (pt)
PH (2) PH18594A (pt)
PL (2) PL244113A1 (pt)
PT (1) PT75442B (pt)
SU (1) SU1189353A3 (pt)
ZA (1) ZA825260B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447363A (en) * 1982-07-07 1984-05-08 E. R. Squibb & Sons, Inc. Androstene-17-dithioketals
US4435326A (en) * 1982-09-09 1984-03-06 E. R. Squibb & Sons, Inc. Intermediates useful in the preparation of 17,17-bis(substituted thio)androstenes
US4420428A (en) * 1982-12-27 1983-12-13 E. R. Squibb & Sons, Inc. 16-Ketoandrostene-17-dithioketals
US4427592A (en) * 1983-01-31 1984-01-24 E. R. Squibb & Sons, Inc. Androstene-17-dithioketals
US4481144A (en) * 1984-02-03 1984-11-06 E. R. Squibb & Sons, Inc. 17-Substituted thia-17-alkyl(or alkenyl or alkynyl)androstenes
US4499021A (en) * 1984-04-12 1985-02-12 E. R. Squibb & Sons, Inc. 17β(Substituted thio)-16-ketoandrostene-17α..-carboxylic acid derivatives
US4529548A (en) * 1984-05-07 1985-07-16 E. R. Squibb & Sons, Inc. 17β-(substituted thio)androstenes
US4528138A (en) * 1984-06-20 1985-07-09 E. R. Squibb & Sons, Inc. 16-Keto-17-substituted thia-17-alkyl(or alkenyl or alkynyl) androstenes
US4529547A (en) * 1984-06-20 1985-07-16 E.R. Squibb & Sons, Inc. 17-(substituted thio)-17-(substituted dithio)androstenes
US4891367A (en) * 1987-04-22 1990-01-02 Merrell Dow Pharmaceuticals Inc. 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
US4868169A (en) * 1987-11-13 1989-09-19 E. R. Squibb & Sons, Inc. Steroid cream formulation
US4868168A (en) * 1987-11-13 1989-09-19 E. R. Squibb & Sons, Inc. Steroid ointment formulation
US5016635A (en) * 1988-11-29 1991-05-21 Sigmedics, Inc. Of Delaware Control of FNS via pattern variations of response EMG
US4883792A (en) * 1989-01-17 1989-11-28 Peter Timmins Steroid cream formulation
GB9103824D0 (en) * 1991-02-23 1991-04-10 Fisons Ag Formulation
IE922301A1 (en) * 1991-07-25 1993-01-27 Squibb & Sons Inc Selective thioketalization process, process for preparing¹thioenol ethers from thioketals, and process for the¹preparation of thioketals
AU672669B2 (en) * 1992-12-24 1996-10-10 Rhone-Poulenc Rorer Limited New steroids
US5344651A (en) * 1993-07-23 1994-09-06 The Procter & Gamble Company Cyproterone acetate thioacetate
US5439901A (en) * 1993-07-23 1995-08-08 The Procter & Gamble Company Cyproterone thiopivalate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2840577A (en) * 1956-12-21 1958-06-24 Searle & Co 17-thio derivatives of estratrien-3-ol and of estratetraen-3-ol
US2949477A (en) * 1959-03-04 1960-08-16 Searle & Co 1, 3, 17-triacetoxyestra-1, 3, 5(10), 16-tetraene and congeners
US4094840A (en) * 1977-05-12 1978-06-13 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones
US4091036A (en) * 1977-05-12 1978-05-23 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4133811A (en) * 1978-02-17 1979-01-09 E. R. Squibb & Sons, Inc. 13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4146538A (en) * 1978-02-27 1979-03-27 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones

Also Published As

Publication number Publication date
DK165838C (da) 1993-06-21
GR76251B (pt) 1984-08-04
ZA825260B (en) 1983-05-25
ES521952A0 (es) 1984-07-01
ES8308336A1 (es) 1983-08-16
KR840001183A (ko) 1984-03-28
AU8631882A (en) 1983-02-24
FI78916C (fi) 1989-10-10
PH18594A (en) 1985-08-12
ATE18671T1 (de) 1986-04-15
HU187783B (en) 1986-02-28
CA1213270A (en) 1986-10-28
ES515110A0 (es) 1983-08-16
JPH035400B2 (pt) 1991-01-25
DK372982A (da) 1983-02-21
DK165838B (da) 1993-01-25
US4361559A (en) 1982-11-30
JPS5841900A (ja) 1983-03-11
NO159601C (no) 1989-01-18
DD215086A5 (de) 1984-10-31
PL244113A1 (en) 1984-05-21
PH19857A (en) 1986-07-22
EP0073026A1 (en) 1983-03-02
NO822823L (no) 1983-02-21
SU1189353A3 (ru) 1985-10-30
ES8406505A1 (es) 1984-07-01
NZ201343A (en) 1985-08-16
AU564228B2 (en) 1987-08-06
PT75442A (en) 1982-09-01
IL66564A (en) 1986-03-31
EP0073026B1 (en) 1986-03-19
DD211567A5 (de) 1984-07-18
PL237936A1 (en) 1984-02-13
PL141303B1 (en) 1987-07-31
CS235959B2 (en) 1985-05-15
IE821951L (en) 1983-02-20
KR890000678B1 (ko) 1989-03-24
ES8406506A1 (es) 1984-07-01
FI822890L (fi) 1983-02-21
FI78916B (fi) 1989-06-30
DE3269987D1 (en) 1986-04-24
NO159601B (no) 1988-10-10
IL66564A0 (en) 1982-12-31
ES521951A0 (es) 1984-07-01
FI822890A0 (fi) 1982-08-19
DD215556A5 (de) 1984-11-14
IE53732B1 (en) 1989-02-01

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980731