DD213919A5 - Verfahren zur herstellung von beta-lactam derivaten - Google Patents

Verfahren zur herstellung von beta-lactam derivaten Download PDF

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Publication number
DD213919A5
DD213919A5 DD83253715A DD25371583A DD213919A5 DD 213919 A5 DD213919 A5 DD 213919A5 DD 83253715 A DD83253715 A DD 83253715A DD 25371583 A DD25371583 A DD 25371583A DD 213919 A5 DD213919 A5 DD 213919A5
Authority
DD
German Democratic Republic
Prior art keywords
amino
group
methyl
phenyl
substituted
Prior art date
Application number
DD83253715A
Other languages
German (de)
English (en)
Inventor
Hermann Breuer
Henner Straub
Uwe D Treuner
Original Assignee
Heyden Gmbh Von
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heyden Gmbh Von filed Critical Heyden Gmbh Von
Publication of DD213919A5 publication Critical patent/DD213919A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD83253715A 1982-08-04 1983-08-04 Verfahren zur herstellung von beta-lactam derivaten DD213919A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40494582A 1982-08-04 1982-08-04

Publications (1)

Publication Number Publication Date
DD213919A5 true DD213919A5 (de) 1984-09-26

Family

ID=23601669

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83253715A DD213919A5 (de) 1982-08-04 1983-08-04 Verfahren zur herstellung von beta-lactam derivaten

Country Status (33)

Country Link
US (1) US4939253A (fr)
JP (1) JPS5993046A (fr)
KR (1) KR900001211B1 (fr)
AR (1) AR241158A1 (fr)
AT (1) AT382367B (fr)
AU (1) AU568086B2 (fr)
BE (1) BE897466A (fr)
CH (1) CH655309A5 (fr)
CS (4) CS243498B2 (fr)
DD (1) DD213919A5 (fr)
DE (1) DE3328047A1 (fr)
DK (1) DK354683A (fr)
ES (1) ES524698A0 (fr)
FI (1) FI832675A (fr)
FR (1) FR2531427A1 (fr)
GB (1) GB2125794B (fr)
GR (1) GR79368B (fr)
HU (1) HU191058B (fr)
IE (1) IE55839B1 (fr)
IL (1) IL69381A (fr)
IN (1) IN160955B (fr)
IT (1) IT1224129B (fr)
LU (1) LU84947A1 (fr)
NL (1) NL8302746A (fr)
NO (1) NO832801L (fr)
NZ (1) NZ205111A (fr)
PL (3) PL257440A1 (fr)
PT (1) PT77155B (fr)
RO (1) RO86511B (fr)
SE (1) SE8304256L (fr)
SU (1) SU1329617A3 (fr)
YU (1) YU43324B (fr)
ZA (1) ZA835470B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939253A (en) * 1982-08-04 1990-07-03 E. R. Squibb & Sons, Inc. 2-oxoazetidin-1-yloxy acetic acids and analogs
US4548747A (en) * 1983-05-02 1985-10-22 E. R. Squibb & Sons, Inc. 3-Acylamino-1-sulfonylaminocarbonylmethoxy-2-azetidinones
ATE39356T1 (de) * 1983-05-31 1989-01-15 Squibb & Sons Inc (((3-acylamino-2-oxo-1-azetidinyl)oxy>methyl>phosphins|ure.
US4534896A (en) * 1983-06-13 1985-08-13 E. R. Squibb & Sons, Inc. 3-Acylamino-2-oxoazetidine-1-(β-oxopropionic acid)
US4548751A (en) * 1983-08-03 1985-10-22 E. R. Squibb & Sons, Inc. (2-Oxo-1-azetidinyloxy)-2-propenoic acid
AU581180B2 (en) * 1983-08-26 1989-02-16 E.R. Squibb & Sons, Inc. 1-(1h-tetrazol-5-ylalkoxy)-2-azetidinones
CA1243679A (fr) * 1983-09-14 1988-10-25 Henner Straub 3-ACYLAMINO-2-OXO-1-AZETIDINYL-.beta.-OXYPROPIONATES
EP0135194A1 (fr) * 1983-09-16 1985-03-27 Takeda Chemical Industries, Ltd. Azétidinones et leur préparation
WO1985004876A1 (fr) * 1984-04-24 1985-11-07 Takeda Chemical Industries, Ltd. Derives de 2-azetidinone et leur procede de preparation
US4576749A (en) * 1983-10-03 1986-03-18 E. R. Squibb & Sons, Inc. 3-Acylamino-1-carboxymethylaminocarbonyl-2-azetidinones
US4559335A (en) * 1983-10-03 1985-12-17 E. R. Squibb & Sons, Inc. 3-Acylamino-1-carboxymethyloxy (or thio) carbonyl-2-azetidinones
US4551277A (en) * 1983-11-09 1985-11-05 E. R. Squibb & Sons, Inc. 4-(3-Acylamino-2-oxo-1-azetidinyl)-4-oxo-2-butenoic acid
US4581170A (en) * 1984-08-03 1986-04-08 E. R. Squibb & Sons, Inc. N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones
EG18314A (en) * 1985-09-26 1993-02-28 Squibb & Sons Inc Process for preparing of 2-oxo-1((substituted sulfonyl)amino)carbonyl)-azitidines
US5112968A (en) * 1989-07-28 1992-05-12 E. R. Squibb & Sons, Inc. Monobactam hydrazide derivatives
EP1827449A4 (fr) * 2004-11-17 2008-01-23 Smithkline Beecham Corp Utilisation de nouveaux composes antibacterieux
RS52068B (en) 2005-12-07 2012-06-30 Basilea Pharmaceutica Ag. USEFUL MANOBACTAM ANTIBIOTICS
WO2014164526A1 (fr) * 2013-03-13 2014-10-09 Rempex Pharmaceuticals, Inc. Antibiotiques à base d'oxamazine
US20140275007A1 (en) * 2013-03-14 2014-09-18 Rempex Pharmaceuticals, Inc. Oxamazin antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ196202A (en) * 1980-02-07 1984-07-31 Squibb & Sons Inc Beta-lactam antibiotics (of azetidine-sulphonic acid type)
EP0048953B1 (fr) * 1980-09-29 1988-03-09 E.R. Squibb & Sons, Inc. Antibiotiques de bêta-lactame
US4337197A (en) * 1980-10-31 1982-06-29 E. R. Squibb & Sons, Inc. O-sulfated β-lactam hydroxamic acids and intermediates
WO1982001873A1 (fr) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd Derives 1-sulfo-2-oxoazetidine et leur procede de preparation
US4939253A (en) * 1982-08-04 1990-07-03 E. R. Squibb & Sons, Inc. 2-oxoazetidin-1-yloxy acetic acids and analogs

Also Published As

Publication number Publication date
NL8302746A (nl) 1984-03-01
PT77155A (en) 1983-09-01
DE3328047A1 (de) 1984-02-09
IL69381A (en) 1987-07-31
RO86511B (ro) 1985-03-31
DK354683D0 (da) 1983-08-03
KR840005814A (ko) 1984-11-19
HU191058B (en) 1986-12-28
RO86511A (fr) 1985-03-15
PL257441A1 (en) 1986-10-07
IE831830L (en) 1984-02-04
SU1329617A3 (ru) 1987-08-07
PL257440A1 (en) 1986-10-07
SE8304256L (sv) 1984-02-05
CS26885A2 (en) 1985-08-31
DK354683A (da) 1984-02-05
FI832675A0 (fi) 1983-07-22
FI832675A (fi) 1984-02-05
YU43324B (en) 1989-06-30
IT1224129B (it) 1990-09-26
PT77155B (en) 1986-01-28
FR2531427B1 (fr) 1985-04-19
CS243498B2 (en) 1986-06-12
CS575983A2 (en) 1985-08-15
GB2125794A (en) 1984-03-14
PL243308A1 (en) 1985-12-17
IT8322430A0 (it) 1983-08-04
ATA281283A (de) 1986-07-15
FR2531427A1 (fr) 1984-02-10
AU568086B2 (en) 1987-12-17
CS26785A2 (en) 1985-08-15
NZ205111A (en) 1986-06-11
CS26783A2 (en) 1985-08-31
SE8304256D0 (sv) 1983-08-03
GB8320497D0 (en) 1983-09-01
ES8502114A1 (es) 1984-12-16
JPS5993046A (ja) 1984-05-29
KR900001211B1 (ko) 1990-02-28
BE897466A (fr) 1984-02-06
AU1755683A (en) 1984-02-09
CS243499B2 (en) 1986-06-12
CS243474B2 (en) 1986-06-12
IE55839B1 (en) 1991-01-30
ES524698A0 (es) 1984-12-16
AT382367B (de) 1987-02-25
IN160955B (fr) 1987-08-22
LU84947A1 (fr) 1984-03-23
GB2125794B (en) 1985-12-18
NO832801L (no) 1984-02-06
AR241158A1 (es) 1991-12-30
IL69381A0 (en) 1983-11-30
US4939253A (en) 1990-07-03
AR241158A2 (es) 1991-12-30
CH655309A5 (fr) 1986-04-15
GR79368B (fr) 1984-10-22
YU162783A (en) 1986-02-28
ZA835470B (en) 1984-04-25

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Legal Events

Date Code Title Description
RPI Change in the person, name or address of the patentee (searches according to art. 11 and 12 extension act)
ENJ Ceased due to non-payment of renewal fee