DD213919A5 - Verfahren zur herstellung von beta-lactam derivaten - Google Patents

Verfahren zur herstellung von beta-lactam derivaten Download PDF

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Publication number
DD213919A5
DD213919A5 DD83253715A DD25371583A DD213919A5 DD 213919 A5 DD213919 A5 DD 213919A5 DD 83253715 A DD83253715 A DD 83253715A DD 25371583 A DD25371583 A DD 25371583A DD 213919 A5 DD213919 A5 DD 213919A5
Authority
DD
German Democratic Republic
Prior art keywords
amino
group
methyl
phenyl
substituted
Prior art date
Application number
DD83253715A
Other languages
German (de)
English (en)
Inventor
Hermann Breuer
Henner Straub
Uwe D Treuner
Original Assignee
Heyden Gmbh Von
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heyden Gmbh Von filed Critical Heyden Gmbh Von
Publication of DD213919A5 publication Critical patent/DD213919A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD83253715A 1982-08-04 1983-08-04 Verfahren zur herstellung von beta-lactam derivaten DD213919A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40494582A 1982-08-04 1982-08-04

Publications (1)

Publication Number Publication Date
DD213919A5 true DD213919A5 (de) 1984-09-26

Family

ID=23601669

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83253715A DD213919A5 (de) 1982-08-04 1983-08-04 Verfahren zur herstellung von beta-lactam derivaten

Country Status (33)

Country Link
US (1) US4939253A (bg)
JP (1) JPS5993046A (bg)
KR (1) KR900001211B1 (bg)
AR (1) AR241158A1 (bg)
AT (1) AT382367B (bg)
AU (1) AU568086B2 (bg)
BE (1) BE897466A (bg)
CH (1) CH655309A5 (bg)
CS (4) CS26783A2 (bg)
DD (1) DD213919A5 (bg)
DE (1) DE3328047A1 (bg)
DK (1) DK354683A (bg)
ES (1) ES8502114A1 (bg)
FI (1) FI832675A (bg)
FR (1) FR2531427A1 (bg)
GB (1) GB2125794B (bg)
GR (1) GR79368B (bg)
HU (1) HU191058B (bg)
IE (1) IE55839B1 (bg)
IL (1) IL69381A (bg)
IN (1) IN160955B (bg)
IT (1) IT1224129B (bg)
LU (1) LU84947A1 (bg)
NL (1) NL8302746A (bg)
NO (1) NO832801L (bg)
NZ (1) NZ205111A (bg)
PL (3) PL257440A1 (bg)
PT (1) PT77155B (bg)
RO (1) RO86511B (bg)
SE (1) SE8304256L (bg)
SU (1) SU1329617A3 (bg)
YU (1) YU43324B (bg)
ZA (1) ZA835470B (bg)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939253A (en) * 1982-08-04 1990-07-03 E. R. Squibb & Sons, Inc. 2-oxoazetidin-1-yloxy acetic acids and analogs
US4548747A (en) * 1983-05-02 1985-10-22 E. R. Squibb & Sons, Inc. 3-Acylamino-1-sulfonylaminocarbonylmethoxy-2-azetidinones
ATE39356T1 (de) * 1983-05-31 1989-01-15 Squibb & Sons Inc (((3-acylamino-2-oxo-1-azetidinyl)oxy>methyl>phosphins|ure.
US4534896A (en) * 1983-06-13 1985-08-13 E. R. Squibb & Sons, Inc. 3-Acylamino-2-oxoazetidine-1-(β-oxopropionic acid)
US4548751A (en) * 1983-08-03 1985-10-22 E. R. Squibb & Sons, Inc. (2-Oxo-1-azetidinyloxy)-2-propenoic acid
AU581180B2 (en) * 1983-08-26 1989-02-16 E.R. Squibb & Sons, Inc. 1-(1h-tetrazol-5-ylalkoxy)-2-azetidinones
CA1243679A (en) * 1983-09-14 1988-10-25 Henner Straub 3-ACYLAMINO-2-OXO-1-AZETIDINYL-.beta.-OXYPROPIONATES
EP0135194A1 (en) * 1983-09-16 1985-03-27 Takeda Chemical Industries, Ltd. Azetidinones and their production
WO1985004876A1 (en) * 1984-04-24 1985-11-07 Takeda Chemical Industries, Ltd. 2-azetidinone derivatives and process for their preparation
US4559335A (en) * 1983-10-03 1985-12-17 E. R. Squibb & Sons, Inc. 3-Acylamino-1-carboxymethyloxy (or thio) carbonyl-2-azetidinones
US4576749A (en) * 1983-10-03 1986-03-18 E. R. Squibb & Sons, Inc. 3-Acylamino-1-carboxymethylaminocarbonyl-2-azetidinones
US4551277A (en) * 1983-11-09 1985-11-05 E. R. Squibb & Sons, Inc. 4-(3-Acylamino-2-oxo-1-azetidinyl)-4-oxo-2-butenoic acid
US4581170A (en) * 1984-08-03 1986-04-08 E. R. Squibb & Sons, Inc. N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones
EG18314A (en) * 1985-09-26 1993-02-28 Squibb & Sons Inc Process for preparing of 2-oxo-1((substituted sulfonyl)amino)carbonyl)-azitidines
US5112968A (en) * 1989-07-28 1992-05-12 E. R. Squibb & Sons, Inc. Monobactam hydrazide derivatives
US20080161249A1 (en) * 2004-11-17 2008-07-03 Smithkline Beecham Corporation Use of Novel Antibacterial Compounds
CN103724330B (zh) * 2005-12-07 2015-08-19 巴斯利尔药物股份公司 单环-内酰胺类抗生素与β-内酰胺酶抑制剂的有效的联合应用
WO2014164526A1 (en) * 2013-03-13 2014-10-09 Rempex Pharmaceuticals, Inc. Oxamazin antibiotics
US20140275007A1 (en) * 2013-03-14 2014-09-18 Rempex Pharmaceuticals, Inc. Oxamazin antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ205240A (en) * 1980-02-07 1984-07-31 Squibb & Sons Inc Sulphonamide derivatives,being starting materials for producing beta-lactams
EP0048953B1 (en) * 1980-09-29 1988-03-09 E.R. Squibb & Sons, Inc. Beta-lactam antibiotics
US4337197A (en) * 1980-10-31 1982-06-29 E. R. Squibb & Sons, Inc. O-sulfated β-lactam hydroxamic acids and intermediates
WO1982001873A1 (en) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd 1-sulfo-2-oxoazetidine derivatives and process for their preparation
US4939253A (en) * 1982-08-04 1990-07-03 E. R. Squibb & Sons, Inc. 2-oxoazetidin-1-yloxy acetic acids and analogs

Also Published As

Publication number Publication date
PT77155B (en) 1986-01-28
AR241158A1 (es) 1991-12-30
JPS5993046A (ja) 1984-05-29
IN160955B (bg) 1987-08-22
GB2125794A (en) 1984-03-14
RO86511A (ro) 1985-03-15
FR2531427A1 (fr) 1984-02-10
SE8304256L (sv) 1984-02-05
ES524698A0 (es) 1984-12-16
KR900001211B1 (ko) 1990-02-28
IE831830L (en) 1984-02-04
IL69381A0 (en) 1983-11-30
CS243499B2 (en) 1986-06-12
AU1755683A (en) 1984-02-09
ZA835470B (en) 1984-04-25
HU191058B (en) 1986-12-28
ES8502114A1 (es) 1984-12-16
FR2531427B1 (bg) 1985-04-19
BE897466A (fr) 1984-02-06
ATA281283A (de) 1986-07-15
CH655309A5 (fr) 1986-04-15
PL257441A1 (en) 1986-10-07
NL8302746A (nl) 1984-03-01
NZ205111A (en) 1986-06-11
SU1329617A3 (ru) 1987-08-07
CS575983A2 (en) 1985-08-15
FI832675A0 (fi) 1983-07-22
SE8304256D0 (sv) 1983-08-03
YU162783A (en) 1986-02-28
DK354683A (da) 1984-02-05
US4939253A (en) 1990-07-03
LU84947A1 (fr) 1984-03-23
PL257440A1 (en) 1986-10-07
CS243474B2 (en) 1986-06-12
RO86511B (ro) 1985-03-31
CS243498B2 (en) 1986-06-12
IT1224129B (it) 1990-09-26
FI832675A (fi) 1984-02-05
GB2125794B (en) 1985-12-18
GB8320497D0 (en) 1983-09-01
IL69381A (en) 1987-07-31
AR241158A2 (es) 1991-12-30
CS26885A2 (en) 1985-08-31
PL243308A1 (en) 1985-12-17
DE3328047A1 (de) 1984-02-09
DK354683D0 (da) 1983-08-03
PT77155A (en) 1983-09-01
NO832801L (no) 1984-02-06
CS26783A2 (en) 1985-08-31
AU568086B2 (en) 1987-12-17
GR79368B (bg) 1984-10-22
IE55839B1 (en) 1991-01-30
KR840005814A (ko) 1984-11-19
AT382367B (de) 1987-02-25
IT8322430A0 (it) 1983-08-04
CS26785A2 (en) 1985-08-15
YU43324B (en) 1989-06-30

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Legal Events

Date Code Title Description
RPI Change in the person, name or address of the patentee (searches according to art. 11 and 12 extension act)
ENJ Ceased due to non-payment of renewal fee