DD210284A5 - Verfahren zur herstellung von 20-aminomakrolidderivaten - Google Patents

Verfahren zur herstellung von 20-aminomakrolidderivaten Download PDF

Info

Publication number
DD210284A5
DD210284A5 DD83254748A DD25474883A DD210284A5 DD 210284 A5 DD210284 A5 DD 210284A5 DD 83254748 A DD83254748 A DD 83254748A DD 25474883 A DD25474883 A DD 25474883A DD 210284 A5 DD210284 A5 DD 210284A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
hydroxy
macrolide
optionally substituted
hydrogen
Prior art date
Application number
DD83254748A
Other languages
German (de)
English (en)
Inventor
Manuel Debono
Herbert A Kirst
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD210284A5 publication Critical patent/DD210284A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD83254748A 1982-09-13 1983-09-12 Verfahren zur herstellung von 20-aminomakrolidderivaten DD210284A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41724782A 1982-09-13 1982-09-13

Publications (1)

Publication Number Publication Date
DD210284A5 true DD210284A5 (de) 1984-06-06

Family

ID=23653182

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83254748A DD210284A5 (de) 1982-09-13 1983-09-12 Verfahren zur herstellung von 20-aminomakrolidderivaten

Country Status (34)

Country Link
EP (1) EP0103465B1 (fi)
JP (1) JPS5973598A (fi)
KR (1) KR850000961B1 (fi)
AR (1) AR241595A1 (fi)
AT (1) AT381707B (fi)
AU (1) AU561147B2 (fi)
BG (1) BG42675A3 (fi)
CA (1) CA1243310A (fi)
CS (1) CS259862B2 (fi)
CY (1) CY1417A (fi)
DD (1) DD210284A5 (fi)
DE (1) DE3366097D1 (fi)
DK (1) DK153555C (fi)
EG (1) EG16287A (fi)
ES (2) ES8604596A1 (fi)
FI (1) FI73222C (fi)
GB (1) GB2127017B (fi)
GR (1) GR79067B (fi)
HK (1) HK21888A (fi)
HU (1) HU194271B (fi)
IE (1) IE55916B1 (fi)
IL (1) IL69666A (fi)
LU (1) LU90240I2 (fi)
MY (1) MY8700756A (fi)
NL (1) NL950001I2 (fi)
NZ (1) NZ205501A (fi)
PH (1) PH23242A (fi)
PL (2) PL142304B1 (fi)
PT (1) PT77335B (fi)
RO (1) RO89235A (fi)
SG (1) SG99287G (fi)
SU (1) SU1375135A3 (fi)
UA (1) UA6045A1 (fi)
ZA (1) ZA836741B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59181294A (ja) * 1983-03-30 1984-10-15 Satoshi Omura 抗生物質ｐｔｌ−４４８とその誘導体およびそれらの製造方法
US4921947A (en) * 1986-03-31 1990-05-01 Eli Lilly And Company Process for preparing macrolide derivatives
US4820694A (en) * 1986-09-29 1989-04-11 Eli Lilly And Company Modifications of 3-O-demethylmycinose in macrocin and lactenocin
EP0262903A3 (en) * 1986-09-29 1988-11-02 Eli Lilly And Company New acyl derivatives of 20-modified tylosin and desmycosin compounds
US5354708A (en) * 1992-06-04 1994-10-11 Taskar Nikhil R Method of nitrogen doping of II-VI semiconductor compounds during epitaxial growth using an amine
TW226373B (fi) * 1992-07-15 1994-07-11 Pfizer
ES2076107B1 (es) * 1993-09-20 1996-04-01 Pfizer Derivados de antibioticos macrolidos de anillos de 16 miembros.
AU3121095A (en) * 1994-09-22 1996-04-09 Pfizer Inc. Antibiotic macrolides
EP0778283A3 (en) * 1995-12-05 1998-01-28 Pfizer Inc. Antibiotic macrolides
US6605599B1 (en) 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
TW565452B (en) * 1998-03-02 2003-12-11 Lilly Co Eli A pharmaceutical composition for use in inhibiting swine infertility and respiratory syndrome virus (SIRSV) proliferation in swine in need of treatment
AU2007278195B2 (en) 2006-07-28 2012-09-13 Intervet International B.V. Macrolide synthesis process
EP2019112A1 (en) 2007-07-26 2009-01-28 Intervet International BV Macrolide solid-state forms
BRPI0820958B1 (pt) * 2007-12-07 2022-04-05 Eisai R&D Management Co., Ltd Compostos macrolídeos
AU2014270353B2 (en) * 2013-05-23 2018-09-20 Elanco Animal Health Gmbh Tylosin derivatives and method for preparation thereof
CN103880903B (zh) * 2014-03-21 2016-06-15 烟台万润药业有限公司 一种泰乐菌素类大环内酯及其衍生物的制备方法
CN117304241B (zh) * 2023-11-30 2024-03-01 中国农业科学院饲料研究所 一种大环内酯类化合物及其制备方法与应用
CN117510561B (zh) * 2023-11-30 2024-04-02 中国农业科学院饲料研究所 一种泰乐菌素衍生物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE32839B1 (en) * 1967-12-04 1973-12-28 Lilly Co Eli Urea-antibiotic adducts and process for preparing the same
US4279896A (en) * 1980-06-23 1981-07-21 Schering Corporation Novel 20-imino macrolide antibacterial agents
JPS58146595A (ja) * 1982-02-25 1983-09-01 Satoshi Omura マクロライド系抗生物質

Also Published As

Publication number Publication date
RO89235A (ro) 1986-03-15
NZ205501A (en) 1985-09-13
GR79067B (fi) 1984-10-02
IE832131L (en) 1984-03-13
HUT35272A (en) 1985-06-28
PL142304B1 (en) 1987-10-31
IL69666A0 (en) 1983-12-30
AT381707B (de) 1986-11-25
EP0103465B1 (en) 1986-09-10
UA6045A1 (uk) 1994-12-29
FI73222B (fi) 1987-05-29
DK153555B (da) 1988-07-25
PT77335B (en) 1986-05-19
FI73222C (fi) 1987-09-10
JPH021840B2 (fi) 1990-01-12
FI833229A (fi) 1984-03-14
PL243718A1 (en) 1985-04-09
PT77335A (en) 1983-10-01
CS665383A2 (en) 1988-04-15
SU1375135A3 (ru) 1988-02-15
CS259862B2 (en) 1988-11-15
ES8607336A1 (es) 1986-06-01
FI833229A0 (fi) 1983-09-09
GB8324044D0 (en) 1983-10-12
CY1417A (en) 1988-04-22
CA1243310A (en) 1988-10-18
ATA320683A (de) 1986-04-15
PL142251B1 (en) 1987-10-31
ZA836741B (en) 1984-04-25
NL950001I2 (nl) 1997-05-01
NL950001I1 (nl) 1995-02-16
LU90240I2 (fr) 1998-07-06
EG16287A (en) 1987-04-30
HU194271B (en) 1988-01-28
DK153555C (da) 1988-12-05
AU561147B2 (en) 1987-04-30
KR840005734A (ko) 1984-11-15
JPS5973598A (ja) 1984-04-25
PL250619A1 (en) 1985-07-30
ES8604596A1 (es) 1986-02-01
DE3366097D1 (en) 1986-10-16
HK21888A (en) 1988-03-31
EP0103465A1 (en) 1984-03-21
DK413783D0 (da) 1983-09-12
ES525544A0 (es) 1986-02-01
IL69666A (en) 1987-10-20
PH23242A (en) 1989-06-06
DK413783A (da) 1984-03-14
GB2127017A (en) 1984-04-04
IE55916B1 (en) 1991-02-27
GB2127017B (en) 1986-01-15
SG99287G (en) 1988-09-23
MY8700756A (en) 1987-12-31
AR241595A1 (es) 1992-09-30
AU1871083A (en) 1984-03-22
KR850000961B1 (ko) 1985-07-02
ES548472A0 (es) 1986-06-01
BG42675A3 (en) 1988-01-15

Similar Documents

Publication Publication Date Title
US4820695A (en) C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antibiotics
DD210284A5 (de) Verfahren zur herstellung von 20-aminomakrolidderivaten
DE69733422T2 (de) 6-0-substituierte ketoliden mit antibakteriellen wirkung
DE69919769T2 (de) 3,6-Ketal-Makrolidantibiotika
DE60220180T2 (de) 14 bis 15 gliedrige makrolide mit antibakterieller aktivität
DE69315839T2 (de) Derivate von 16-gliedrigen antibiotischen macroliden
DE69821009T2 (de) 6,9-verbrückte erythromycin-derivate
DE69317877T2 (de) 4''-deoxyerythromycinderivate
EP0203621B1 (en) C-20-modified macrolide derivatives
US4440759A (en) 20-Amino tylosin derivatives and pharmaceutical compositions containing same
DE69402714T2 (de) Amid-derivate von 16-gliedrige heterocyclen als antibiotische macrolide
DE2804508C2 (de) Epimere 4"-substituierte Aminoderivate des Oleandomycins und deren Verwendung als antibakterielle Wirkstoffe
DD210060A5 (de) Verfahren zur herstellung von 5-0-mycaminosyltylonolidderivaten
US4820694A (en) Modifications of 3-O-demethylmycinose in macrocin and lactenocin
US4452784A (en) C-23-Modified derivatives of DMT
AT390733B (de) Verfahren zur behandlung oder unterdrueckung mikrobieller infektionen in einem warmbluetigen tier
DE60115851T2 (de) Anti-infektionsmittel, die gegen gegenüber mehreren arzneimitteln resistente bakterienstämme nützlich sind
US4604380A (en) C-23-substituted mycaminosyltylonolide compounds, pharmaceutical compositions and methods of use
DE69313871T2 (de) Antiparasitisches mittel
CH660366A5 (de) 23-0-acyl-23-demycinosyldesmycosin-derivate.
US4581346A (en) Macrolide derivatives
BG60758B2 (bg) С-20-дихидро-дезокси-(циклени амино)-производни на макролидни антибиотици
DE2631886A1 (de) Isoleucomycin a tief 5 , verfahren zu seiner herstellung und es enthaltende arzneimittel
DE2701625A1 (de) Macrolid-antibiotika, deren salze und ester, verfahren zu ihrer herstellung und arzneipraeparate