DE69402714T2 - Amid-derivate von 16-gliedrige heterocyclen als antibiotische macrolide - Google Patents

Amid-derivate von 16-gliedrige heterocyclen als antibiotische macrolide

Info

Publication number
DE69402714T2
DE69402714T2 DE69402714T DE69402714T DE69402714T2 DE 69402714 T2 DE69402714 T2 DE 69402714T2 DE 69402714 T DE69402714 T DE 69402714T DE 69402714 T DE69402714 T DE 69402714T DE 69402714 T2 DE69402714 T2 DE 69402714T2
Authority
DE
Germany
Prior art keywords
pct
amide derivatives
macrolid
heterocycles
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69402714T
Other languages
English (en)
Other versions
DE69402714D1 (de
Inventor
Kristin LUNDY
Chi Vu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE69402714D1 publication Critical patent/DE69402714D1/de
Publication of DE69402714T2 publication Critical patent/DE69402714T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE69402714T 1993-07-15 1994-07-04 Amid-derivate von 16-gliedrige heterocyclen als antibiotische macrolide Expired - Fee Related DE69402714T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9218193A 1993-07-15 1993-07-15
US19331694A 1994-02-08 1994-02-08
PCT/IB1994/000199 WO1995002594A1 (en) 1993-07-15 1994-07-04 Amide derivatives of 16-membered ring antibiotic macrolides

Publications (2)

Publication Number Publication Date
DE69402714D1 DE69402714D1 (de) 1997-05-22
DE69402714T2 true DE69402714T2 (de) 1997-07-31

Family

ID=26785371

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69402714T Expired - Fee Related DE69402714T2 (de) 1993-07-15 1994-07-04 Amid-derivate von 16-gliedrige heterocyclen als antibiotische macrolide

Country Status (10)

Country Link
US (1) US5716939A (de)
EP (1) EP0708770B1 (de)
JP (1) JPH08508038A (de)
AT (1) ATE151767T1 (de)
AU (1) AU6980094A (de)
CA (1) CA2167201A1 (de)
DE (1) DE69402714T2 (de)
FI (1) FI943358A (de)
IL (1) IL110240A0 (de)
WO (1) WO1995002594A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3121095A (en) * 1994-09-22 1996-04-09 Pfizer Inc. Antibiotic macrolides
EP0778283A3 (de) * 1995-12-05 1998-01-28 Pfizer Inc. Antibiotische Makrolide
US6605599B1 (en) 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
FR2775187B1 (fr) * 1998-02-25 2003-02-21 Novartis Ag Utilisation de l'epothilone b pour la fabrication d'une preparation pharmaceutique antiproliferative et d'une composition comprenant l'epothilone b comme agent antiproliferatif in vivo
US6440942B1 (en) 2000-12-22 2002-08-27 Enanta Pharmaceuticals, Inc. 14-membered macrolides derived from leucomycins
US6462026B1 (en) 2001-02-16 2002-10-08 Enanta Pharmaceuticals, Inc. Bicyclic leucomycins
US6436906B1 (en) 2001-04-02 2002-08-20 Enanta Pharmaceuticals, Inc. 9-amino-14-membered macrolides derived from leucomycins
US6680299B2 (en) 2001-07-27 2004-01-20 Enanta Pharmaceuticals, Inc. 4'-substituted leucomycins
ES2337134T3 (es) 2002-03-12 2010-04-21 Bristol-Myers Squibb Company Derivados de c3-ciano-epotilona.
US6753415B2 (en) 2002-04-19 2004-06-22 Enanta Pharmaceuticals, Inc. 23-O-substituted 5-O-mycaminosyltylonide derivatives
US6710034B2 (en) 2002-04-19 2004-03-23 Enanta Pharmaceuticals, Inc. 5-O-mycaminosyltylonide derivatives
AU2006206952B2 (en) 2005-01-24 2011-08-18 Microbial Chemistry Research Foundation Anti-penicillin resistant pneumococci agent and novel 16-membered ring macrolide derivative
US8227429B2 (en) 2006-07-28 2012-07-24 Intervet International B.V. Macrolide synthesis process and solid-state forms
US8463852B2 (en) * 2006-10-06 2013-06-11 Oracle International Corporation Groupware portlets for integrating a portal with groupware systems
CN109557216B (zh) * 2019-01-22 2020-02-18 中国农业科学院农业质量标准与检测技术研究所 菜籽粕中掺加泰乐菌素滤渣的鉴别方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR394135A (fr) * 1908-07-23 1909-01-15 Paul Jean Baptiste Francois Tambour laveur continu
US3975372A (en) * 1975-02-28 1976-08-17 Schering Corporation Preparation of 12,13-desepoxy-12,13-dehydrorosamicin
US4056616A (en) * 1976-03-05 1977-11-01 Schering Corporation Rosamicin derivatives and method of using same
US4279896A (en) * 1980-06-23 1981-07-21 Schering Corporation Novel 20-imino macrolide antibacterial agents
US4304856A (en) * 1980-11-10 1981-12-08 Eli Lilly And Company Process for producing 20-dihydro-20-deoxy-23-demycinosyltylosin
CA1196915A (en) * 1982-01-22 1985-11-19 Hideo Sakakibara 23-0-acyl-23-demycinosyldesmycosin
US4515941A (en) * 1982-04-07 1985-05-07 Toyo Jozo Kabushiki Kaisha 23-Demycinosyldesmycosin derivatives
US4629786A (en) * 1983-02-28 1986-12-16 Eli Lilly And Company C-20- and C-23 modified macrolide derivatives
IL71032A0 (en) * 1983-02-28 1984-05-31 Lilly Co Eli C-20 and c-23-modified macrolide derivatives
CA1238044A (en) * 1983-11-30 1988-06-14 Tatsuro Fujiwara 14-de (hydroxymethyl)-mycaminosyltylonolide
US4604380A (en) * 1985-01-18 1986-08-05 Eli Lilly And Company C-23-substituted mycaminosyltylonolide compounds, pharmaceutical compositions and methods of use
JPS62103098A (ja) * 1985-05-13 1987-05-13 Microbial Chem Res Found タイロシン誘導体
US4921947A (en) * 1986-03-31 1990-05-01 Eli Lilly And Company Process for preparing macrolide derivatives
JPS62242694A (ja) * 1986-04-15 1987-10-23 Toyo Jozo Co Ltd ２０−０−アシル−１９，２０−エノ−ルマクロライド系抗生物質誘導体
US4920103A (en) * 1986-09-29 1990-04-24 Eli Lilly And Company Modifications of mycinose and 3-O-demethylmycinose in tylosin-type macrolides
US4962146A (en) * 1987-04-29 1990-10-09 Schering Corporation 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives
FR2638458A1 (fr) * 1988-10-27 1990-05-04 Adir Nouveaux derives de la tylosine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5026832A (en) * 1988-12-26 1991-06-25 Toyo Jozo Co., Ltd. 9-dihydro-9-O-alkyldesmycosin derivatives
FR2646081A1 (de) * 1989-04-20 1990-10-26 Adir
US5140014A (en) * 1989-11-13 1992-08-18 Abbott Laboratories Rosaramicin derivatives and method of treating bacterial infections
JPH05117292A (ja) * 1991-10-24 1993-05-14 Meiji Seika Kaisha Ltd 新規１６員環マクロリド誘導体及びその製造法
TW226373B (de) * 1992-07-15 1994-07-11 Pfizer

Also Published As

Publication number Publication date
ATE151767T1 (de) 1997-05-15
CA2167201A1 (en) 1995-01-26
DE69402714D1 (de) 1997-05-22
EP0708770A1 (de) 1996-05-01
US5716939A (en) 1998-02-10
FI943358A0 (fi) 1994-07-14
JPH08508038A (ja) 1996-08-27
EP0708770B1 (de) 1997-04-16
AU6980094A (en) 1995-02-13
WO1995002594A1 (en) 1995-01-26
FI943358A (fi) 1995-01-16
IL110240A0 (en) 1994-10-21

Similar Documents

Publication Publication Date Title
DE69315839T2 (de) Derivate von 16-gliedrigen antibiotischen macroliden
DE69402714D1 (de) Amid-derivate von 16-gliedrige heterocyclen als antibiotische macrolide
PT759774E (pt) Metodo para o tratamento de infeccoes bacterianas gram-negativas por administracao de um produto de proteina bactericida indutora da permeabilidade (bip) e de um antibiotico
ATE266036T1 (de) 6-o-substitutierte makroliden mit antibakterieller wirkung
HUP0004579A2 (hu) Antibakteriális hatású, a 3'-N-pozícióban módosított szerkezetű 6-0-szubsztituált-eritromicin-ketolid-származékok és ezeket tartalmazó gyógyszerkészítmények
RU94042916A (ru) 9a-n - (n'-карбамоил) - и 9a-n - (n'-тиокарбамоил) производные 9-деоксо- 9a - аза - 9a - гомоэтирмицина а, способ их получения и фармкомпозиция на их основе
ATE205505T1 (de) Basische oxazolinamid-derivate von ge2270 und ge2270-änlichen antibiotika
DK0801655T3 (da) Basiske prolinamidderivater af GE 2270 og GE 2270-lignende antibiotika
CA2332686A1 (en) Novel 13 and 14-membered antibacterial and prokinetic macrolides and their intermediates
ATE302013T1 (de) Azithromycin enthaltende zusammensetzungen zur kontrolle von emesis bei hunden
BG106123A (en) Diphosphate salt of a 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin derivative and its pharmaceutical composition
PL324884A1 (en) Application of prostane derivatives and their compositions with antibiotics in treating bacterial infections
DE69626040D1 (de) 3-deoxy-3-descladinosederivate von erythromycin a und b
NO950143L (no) Derivater av antibiotiske makrolider med 16-leddet ring
ES2076107A1 (es) Derivados de antibioticos macrolidos de anillos de 16 miembros.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee