DK413783A - Fremgangsmaade til fremstilling af 20-amino-macrolidderivater eller syreadditionssalte deraf - Google Patents

Fremgangsmaade til fremstilling af 20-amino-macrolidderivater eller syreadditionssalte deraf Download PDF

Info

Publication number
DK413783A
DK413783A DK413783A DK413783A DK413783A DK 413783 A DK413783 A DK 413783A DK 413783 A DK413783 A DK 413783A DK 413783 A DK413783 A DK 413783A DK 413783 A DK413783 A DK 413783A
Authority
DK
Denmark
Prior art keywords
amino
preparing
acid addition
addition salts
macrolide derivatives
Prior art date
Application number
DK413783A
Other languages
English (en)
Other versions
DK153555C (da
DK413783D0 (da
DK153555B (da
Inventor
Manuel Debono
Herbert Andrew Kirst
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK413783D0 publication Critical patent/DK413783D0/da
Publication of DK413783A publication Critical patent/DK413783A/da
Publication of DK153555B publication Critical patent/DK153555B/da
Application granted granted Critical
Publication of DK153555C publication Critical patent/DK153555C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DK413783A 1982-09-13 1983-09-12 Analogifremgangsmaade til fremstilling af 20-amino-derivater af tylosin, desmycosin, macrosin eller lactenocin eller syreadditionssalte deraf DK153555C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41724782A 1982-09-13 1982-09-13
US41724782 1982-09-13

Publications (4)

Publication Number Publication Date
DK413783D0 DK413783D0 (da) 1983-09-12
DK413783A true DK413783A (da) 1984-03-14
DK153555B DK153555B (da) 1988-07-25
DK153555C DK153555C (da) 1988-12-05

Family

ID=23653182

Family Applications (1)

Application Number Title Priority Date Filing Date
DK413783A DK153555C (da) 1982-09-13 1983-09-12 Analogifremgangsmaade til fremstilling af 20-amino-derivater af tylosin, desmycosin, macrosin eller lactenocin eller syreadditionssalte deraf

Country Status (34)

Country Link
EP (1) EP0103465B1 (da)
JP (1) JPS5973598A (da)
KR (1) KR850000961B1 (da)
AR (1) AR241595A1 (da)
AT (1) AT381707B (da)
AU (1) AU561147B2 (da)
BG (1) BG42675A3 (da)
CA (1) CA1243310A (da)
CS (1) CS259862B2 (da)
CY (1) CY1417A (da)
DD (1) DD210284A5 (da)
DE (1) DE3366097D1 (da)
DK (1) DK153555C (da)
EG (1) EG16287A (da)
ES (2) ES8604596A1 (da)
FI (1) FI73222C (da)
GB (1) GB2127017B (da)
GR (1) GR79067B (da)
HK (1) HK21888A (da)
HU (1) HU194271B (da)
IE (1) IE55916B1 (da)
IL (1) IL69666A (da)
LU (1) LU90240I2 (da)
MY (1) MY8700756A (da)
NL (1) NL950001I2 (da)
NZ (1) NZ205501A (da)
PH (1) PH23242A (da)
PL (2) PL142251B1 (da)
PT (1) PT77335B (da)
RO (1) RO89235A (da)
SG (1) SG99287G (da)
SU (1) SU1375135A3 (da)
UA (1) UA6045A1 (da)
ZA (1) ZA836741B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59181294A (ja) * 1983-03-30 1984-10-15 Satoshi Omura 抗生物質ｐｔｌ−４４８とその誘導体およびそれらの製造方法
US4921947A (en) * 1986-03-31 1990-05-01 Eli Lilly And Company Process for preparing macrolide derivatives
EP0262903A3 (en) * 1986-09-29 1988-11-02 Eli Lilly And Company New acyl derivatives of 20-modified tylosin and desmycosin compounds
US4820694A (en) * 1986-09-29 1989-04-11 Eli Lilly And Company Modifications of 3-O-demethylmycinose in macrocin and lactenocin
US5354708A (en) * 1992-06-04 1994-10-11 Taskar Nikhil R Method of nitrogen doping of II-VI semiconductor compounds during epitaxial growth using an amine
TW226373B (da) * 1992-07-15 1994-07-11 Pfizer
ES2076107B1 (es) * 1993-09-20 1996-04-01 Pfizer Derivados de antibioticos macrolidos de anillos de 16 miembros.
WO1996009312A1 (en) * 1994-09-22 1996-03-28 Pfizer Inc. Antibiotic macrolides
EP0778283A3 (en) * 1995-12-05 1998-01-28 Pfizer Inc. Antibiotic macrolides
US6605599B1 (en) 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
TW565452B (en) * 1998-03-02 2003-12-11 Lilly Co Eli A pharmaceutical composition for use in inhibiting swine infertility and respiratory syndrome virus (SIRSV) proliferation in swine in need of treatment
KR101456308B1 (ko) 2006-07-28 2014-11-03 인터벳 인터내셔널 비.브이. 마크롤라이드 합성 방법
EP2019112A1 (en) 2007-07-26 2009-01-28 Intervet International BV Macrolide solid-state forms
RU2497803C2 (ru) * 2007-12-07 2013-11-10 ЭЙСАЙ Ар ЭНД Ди МЕНЕДЖМЕНТ КО., ЛТД Промежуточные продукты в синтезе аналогов зеараленоновых макролидов
MX361808B (es) * 2013-05-23 2018-12-14 Bayer Animal Health Gmbh Derivados de tilosina y metodo para su preparacion.
CN103880903B (zh) * 2014-03-21 2016-06-15 烟台万润药业有限公司 一种泰乐菌素类大环内酯及其衍生物的制备方法
CN117510561B (zh) * 2023-11-30 2024-04-02 中国农业科学院饲料研究所 一种泰乐菌素衍生物及其制备方法与应用
CN117304241B (zh) * 2023-11-30 2024-03-01 中国农业科学院饲料研究所 一种大环内酯类化合物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE32839B1 (en) * 1967-12-04 1973-12-28 Lilly Co Eli Urea-antibiotic adducts and process for preparing the same
US4279896A (en) * 1980-06-23 1981-07-21 Schering Corporation Novel 20-imino macrolide antibacterial agents
JPS58146595A (ja) * 1982-02-25 1983-09-01 Satoshi Omura マクロライド系抗生物質

Also Published As

Publication number Publication date
GB8324044D0 (en) 1983-10-12
NZ205501A (en) 1985-09-13
FI833229A0 (fi) 1983-09-09
EP0103465B1 (en) 1986-09-10
CY1417A (en) 1988-04-22
PL250619A1 (en) 1985-07-30
SG99287G (en) 1988-09-23
AU1871083A (en) 1984-03-22
NL950001I2 (nl) 1997-05-01
DE3366097D1 (en) 1986-10-16
IE55916B1 (en) 1991-02-27
DK153555C (da) 1988-12-05
GB2127017B (en) 1986-01-15
LU90240I2 (fr) 1998-07-06
HU194271B (en) 1988-01-28
RO89235A (ro) 1986-03-15
CS259862B2 (en) 1988-11-15
EP0103465A1 (en) 1984-03-21
MY8700756A (en) 1987-12-31
PH23242A (en) 1989-06-06
HUT35272A (en) 1985-06-28
IE832131L (en) 1984-03-13
ES8607336A1 (es) 1986-06-01
CA1243310A (en) 1988-10-18
PT77335B (en) 1986-05-19
KR850000961B1 (ko) 1985-07-02
GB2127017A (en) 1984-04-04
KR840005734A (ko) 1984-11-15
HK21888A (en) 1988-03-31
JPH021840B2 (da) 1990-01-12
FI73222B (fi) 1987-05-29
CS665383A2 (en) 1988-04-15
FI833229A (fi) 1984-03-14
JPS5973598A (ja) 1984-04-25
ES8604596A1 (es) 1986-02-01
NL950001I1 (nl) 1995-02-16
ATA320683A (de) 1986-04-15
PL243718A1 (en) 1985-04-09
AU561147B2 (en) 1987-04-30
BG42675A3 (en) 1988-01-15
ZA836741B (en) 1984-04-25
AR241595A1 (es) 1992-09-30
SU1375135A3 (ru) 1988-02-15
UA6045A1 (uk) 1994-12-29
GR79067B (da) 1984-10-02
IL69666A0 (en) 1983-12-30
ES548472A0 (es) 1986-06-01
DK413783D0 (da) 1983-09-12
FI73222C (fi) 1987-09-10
EG16287A (en) 1987-04-30
DD210284A5 (de) 1984-06-06
PT77335A (en) 1983-10-01
PL142304B1 (en) 1987-10-31
ES525544A0 (es) 1986-02-01
DK153555B (da) 1988-07-25
IL69666A (en) 1987-10-20
PL142251B1 (en) 1987-10-31
AT381707B (de) 1986-11-25

Similar Documents

Publication Publication Date Title
DK144783D0 (da) Fremgangsmade til fremstilling af cycloalka(c)pyrrol-carboxylsyrederivater
DK74282A (da) Fremgangsmaade til fremstilling af imidazodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf
DK405881A (da) Fremgangsmaade til fremstilling af 7beta-aminothiadiazolylacetylamino3-ammoniomethyl-3-cephem-4-carboxylsyreforbindelser eller salte deraf
DK413783A (da) Fremgangsmaade til fremstilling af 20-amino-macrolidderivater eller syreadditionssalte deraf
DK483681A (da) Fremgangsmaade til fremstilling af 1-carboxy-(azaalkanoyl eller azaaralkanoyl)-indolin-2-carboxylsyrer eller salte deraf
DK453181A (da) Fremgangsmaade til fremstilling af 2-quanidino-4-heteroaryl-thiazolforbindelser eller syreadditionssalte deraf
DK334581A (da) Fremgangsmaade til frmstilling af 9-amino-1-hydroxyotahydro-6h-benzo (c) quinolin-derivater eller syreadditionssalte deraf
DK160421C (da) Analogifremgangsmaade til fremstilling af 4-oxo-1,4-dihydronicotinsyrederivater eller salte deraf
DK294780A (da) Fremgangsmaade til fremstilling af trans-3-(4-oxo4h-quinazolin-3-yl)-2-propensyrederivater eller salte deraf
DK166087C (da) Fremgangsmaade til fremstilling af oe(3-amino-3-carboxy)-propyl-1aaphosphinsyrederivater
DK358183D0 (da) Fremgangsmade til fremstilling af alfa-aryl-alkansyrer eller salte deraf
DK184481A (da) Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf
DK495780A (da) Fremgangsmaade til fremstilling af 2-keto-l-gulonsyre eller salte deraf
DK98383A (da) Fremgangsmaade til fremstilling af 1,2,4-triazol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf
DK155081A (da) Fremgangsmaade til fremstilling af 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaensyre eller salte heraf
DK160043C (da) Analogifremgangsmaade til fremstilling af n-alk-2-en-4-yn-yl-benzothienylalkylaminer eller syreadditionssalte deraf
DK300080A (da) Fremgangsmaade til fremstilling af ergol-8-en-eller ergolinforbindelser eller syreadditionsalte deraf
DK250883D0 (da) Fremgangsmade til fremstilling af pyrimidinoner eller deres syreadditionssalte
DK154085C (da) Fremgangsmaade til fremstilling af 1,1-dioxopenicillansyrederivater
DK208981A (da) Fremgangsmaade til fremstilling af benzoxazol- eller benzothiazol-2-carboxylsyreestere eller syreadditionssalte eller konjugatsalte deraf
DK260080A (da) Fremgangsmaade til fremstilling af 2-amino-alkyl5-phenyl-hexahydro-trans-4a,9b-pyrido (4,3-b)indoler eller syreadditionssalte deraf
DK234182A (da) Fremgangsmaade til fremstilling af heterocyclisk substitueredeamidoximer eller syreadditionssalte deraf
DK109781A (da) Fremgangsmaade til fremstilling af 7-betaaminoisothiazolylacetamido-3-cephem-4-carboxylsyreforbindelser eller salte deraf
DK295782A (da) Fremgangsmaade til fremstilling af cystinderivater eller syreadditionssalte deraf
DK412783A (da) Fremgangsmaade til fremstilling af 7alfa-alkyl-17alfa-pregn-4-en-21,17-carbolactoner og -21-carboxylsyresalte

Legal Events

Date Code Title Description
CTFF Application for supplementary protection certificate (spc) filed

Spc suppl protection certif: CA 2000 00001

Filing date: 20000104

Extension date: 20050625

PUP Patent expired