DK184481A - Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf - Google Patents

Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf

Info

Publication number
DK184481A
DK184481A DK184481A DK184481A DK184481A DK 184481 A DK184481 A DK 184481A DK 184481 A DK184481 A DK 184481A DK 184481 A DK184481 A DK 184481A DK 184481 A DK184481 A DK 184481A
Authority
DK
Denmark
Prior art keywords
procedure
additional salts
anthracycline derivatives
acid additional
preparing
Prior art date
Application number
DK184481A
Other languages
English (en)
Other versions
DK165790B (da
DK165790C (da
Inventor
H Umezawa
T Takeuchi
H Naganawa
K Tatsuta
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of DK184481A publication Critical patent/DK184481A/da
Publication of DK165790B publication Critical patent/DK165790B/da
Application granted granted Critical
Publication of DK165790C publication Critical patent/DK165790C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK184481A 1980-04-26 1981-04-24 Fremgangsmaade til fremstilling af adriamycin-4'-o-derivater eller syreadditionssalte deraf DK165790C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5597480A JPS56156300A (en) 1980-04-26 1980-04-26 Novel preparative method of anthracyclin derivative
JP5597480 1980-04-26

Publications (3)

Publication Number Publication Date
DK184481A true DK184481A (da) 1981-10-27
DK165790B DK165790B (da) 1993-01-18
DK165790C DK165790C (da) 1993-06-14

Family

ID=13014042

Family Applications (1)

Application Number Title Priority Date Filing Date
DK184481A DK165790C (da) 1980-04-26 1981-04-24 Fremgangsmaade til fremstilling af adriamycin-4'-o-derivater eller syreadditionssalte deraf

Country Status (7)

Country Link
US (1) US4360664A (da)
EP (1) EP0039060B1 (da)
JP (1) JPS56156300A (da)
CA (1) CA1157016A (da)
DE (1) DE3175057D1 (da)
DK (1) DK165790C (da)
ES (1) ES8202833A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6016998A (ja) * 1983-07-07 1985-01-28 Microbial Chem Res Found アントラサイクリン誘導体の製造方法
JPS61502956A (ja) * 1984-06-14 1986-12-18 ビオガル　ジヨジセルジヤ−ル アドリアマイシン及びそのハロゲン化塩の調整法
JPS62116591A (ja) * 1985-11-16 1987-05-28 Microbial Chem Res Found ４′−Ｏ−テトラヒドロピラニルアドリアマイシンｂの製造方法
US4889926A (en) * 1987-06-12 1989-12-26 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Method for the synthesis of (2"R)-4'-O-tetra-hydropyranyladriamycim using 14-chloro-daunomycin as an intermediate
US4997922A (en) * 1988-09-06 1991-03-05 Sanraku Incorporated Anthracycline derivatives
IT1230505B (it) * 1988-10-11 1991-10-25 Sicor Spa Procedimento per la conversione della daunorubicina in doxorubicina.
US5776458A (en) * 1990-12-05 1998-07-07 Pharmacia & Upjohn S.P.A. Anthracycline-conjugates
GB9026491D0 (en) * 1990-12-05 1991-01-23 Erba Carlo Spa Anthracycline-conjugates
EP1525002A1 (en) * 2002-07-24 2005-04-27 Universite Catholique De Louvain Method for the synthesis of anthracycline-peptide conjugates
CN103087124B (zh) * 2012-11-21 2016-01-13 浙江海正药业股份有限公司 一种制备阿霉素的方法
CN108484689B (zh) * 2018-03-06 2020-11-10 道中道（菏泽）制药有限公司 一种戊柔比星合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1527892A (fr) * 1967-03-15 1968-06-07 Rhone Poulenc Sa Nouveau procédé de préparation de l'antibiotique 13057 r.p.
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
NL170737C (nl) * 1975-11-12 1982-12-16 Rhone Poulenc Ind Werkwijze voor het bereiden van tegen tumoren werkzame esters van adriamycine, alsmede voor het bereiden van geneesmiddelen met anti-tumoractiviteit.
GB1561507A (en) * 1976-11-17 1980-02-20 Farmaceutici Italia Snthracycline disaccharides
JPS5430146A (en) * 1977-08-05 1979-03-06 Microbial Chem Res Found Novel anthracycline derivatives and their preparation
DK160616C (da) * 1979-02-03 1991-09-02 Zaidan Hojin Biseibutsu Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf
ATE4387T1 (de) * 1979-07-04 1983-08-15 Farmitalia Carlo Erba S.P.A. Anthracyclin-glycoside, verfahren zu ihrer herstellung und sie enthaltende therapeutische zusammensetzung.

Also Published As

Publication number Publication date
US4360664A (en) 1982-11-23
CA1157016A (en) 1983-11-15
EP0039060A1 (en) 1981-11-04
DK165790B (da) 1993-01-18
JPS56156300A (en) 1981-12-02
DE3175057D1 (en) 1986-09-11
EP0039060B1 (en) 1986-08-06
DK165790C (da) 1993-06-14
JPS6259719B2 (da) 1987-12-12
ES501572A0 (es) 1982-02-16
ES8202833A1 (es) 1982-02-16

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