DK483681A - Fremgangsmaade til fremstilling af 1-carboxy-(azaalkanoyl eller azaaralkanoyl)-indolin-2-carboxylsyrer eller salte deraf - Google Patents

Fremgangsmaade til fremstilling af 1-carboxy-(azaalkanoyl eller azaaralkanoyl)-indolin-2-carboxylsyrer eller salte deraf

Info

Publication number
DK483681A
DK483681A DK483681A DK483681A DK483681A DK 483681 A DK483681 A DK 483681A DK 483681 A DK483681 A DK 483681A DK 483681 A DK483681 A DK 483681A DK 483681 A DK483681 A DK 483681A
Authority
DK
Denmark
Prior art keywords
azaaralkanoyl
azaalkanoyl
indoline
carboxy
salts
Prior art date
Application number
DK483681A
Other languages
English (en)
Inventor
H B Renfreo
J L Stanton
A Sele
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK483681A publication Critical patent/DK483681A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK483681A 1980-11-03 1981-11-02 Fremgangsmaade til fremstilling af 1-carboxy-(azaalkanoyl eller azaaralkanoyl)-indolin-2-carboxylsyrer eller salte deraf DK483681A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20376980A 1980-11-03 1980-11-03
US23991881A 1981-03-03 1981-03-03

Publications (1)

Publication Number Publication Date
DK483681A true DK483681A (da) 1982-05-04

Family

ID=26898886

Family Applications (1)

Application Number Title Priority Date Filing Date
DK483681A DK483681A (da) 1980-11-03 1981-11-02 Fremgangsmaade til fremstilling af 1-carboxy-(azaalkanoyl eller azaaralkanoyl)-indolin-2-carboxylsyrer eller salte deraf

Country Status (13)

Country Link
EP (1) EP0051301A1 (da)
AU (1) AU7702281A (da)
CA (1) CA1172258A (da)
DD (1) DD201888A5 (da)
DK (1) DK483681A (da)
ES (3) ES506784A0 (da)
FI (1) FI813422L (da)
GB (1) GB2086390B (da)
GR (1) GR74689B (da)
HU (1) HU185324B (da)
IL (1) IL64185A0 (da)
NO (1) NO813694L (da)
PT (1) PT73916B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN156096B (da) * 1981-03-19 1985-05-11 Usv Pharma Corp
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
NZ202903A (en) * 1981-12-29 1988-01-08 Hoechst Ag 1-- pe pyrrol-2-yl-carboxylic acid derivatives and pharmaceutical compositions
ATE25244T1 (de) * 1981-12-29 1987-02-15 Hoechst Ag Neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung.
DE3210496A1 (de) * 1982-03-23 1983-10-06 Hoechst Ag Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
US4520205A (en) * 1982-06-28 1985-05-28 American Home Products Corporation Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
FR2546886B2 (fr) * 1983-06-06 1986-05-16 Adir Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant
DE3324263A1 (de) * 1983-07-06 1985-01-17 Hoechst Ag, 6230 Frankfurt Derivate der 2-azabicyclo(3.1.0)hexan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(3.1.0)hexan-derivate als zwischenprodukte und verfahren zu deren herstellung
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3333454A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
TW197945B (da) * 1990-11-27 1993-01-11 Hoechst Ag
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
JPH09500113A (ja) * 1993-06-30 1997-01-07 チバ−ガイギー アクチェンゲゼルシャフト エンケファリナーゼ及びａｃｅのインヒビターとして有用な抗高血圧性三環式アゼピン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4303583A (en) * 1979-08-13 1981-12-01 American Home Products Corporation 1H,5H-[1,4]Thiazepino[4,3-a]indole-1,5-diones
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids

Also Published As

Publication number Publication date
PT73916A (en) 1981-12-01
AU7702281A (en) 1982-05-13
ES8303329A1 (es) 1983-02-01
HU185324B (en) 1985-01-28
CA1172258A (en) 1984-08-07
FI813422L (fi) 1982-05-04
ES516556A0 (es) 1983-12-01
GR74689B (da) 1984-07-03
IL64185A0 (en) 1982-02-28
PT73916B (en) 1983-11-30
ES8401026A1 (es) 1983-12-01
NO813694L (no) 1982-05-04
ES506784A0 (es) 1983-02-01
DD201888A5 (de) 1983-08-17
GB2086390A (en) 1982-05-12
EP0051301A1 (de) 1982-05-12
GB2086390B (en) 1984-06-06
ES8401025A1 (es) 1983-12-01
ES516555A0 (es) 1983-12-01

Similar Documents

Publication Publication Date Title
DK483681A (da) Fremgangsmaade til fremstilling af 1-carboxy-(azaalkanoyl eller azaaralkanoyl)-indolin-2-carboxylsyrer eller salte deraf
DK331881A (da) Fremgangsmaade til fremstilling af trisubstituerede imidazolderivater eller salte deraf
DK28282A (da) Fremgangsmaade til fremstilling af hexapyranoseforbindelser eller salte deraf
DK405881A (da) Fremgangsmaade til fremstilling af 7beta-aminothiadiazolylacetylamino3-ammoniomethyl-3-cephem-4-carboxylsyreforbindelser eller salte deraf
DK552581A (da) Fremgangsmaade til fremstilling af 3-pyridylaklyl-indol-forbindelser eller farmaceutisk acceptable salte deraf
DK294780A (da) Fremgangsmaade til fremstilling af trans-3-(4-oxo4h-quinazolin-3-yl)-2-propensyrederivater eller salte deraf
DK536480A (da) Fremgangsmaade til fremtlling af isoquinolineddikesyre-forbindelser eller salte deraf
DK413783A (da) Fremgangsmaade til fremstilling af 20-amino-macrolidderivater eller syreadditionssalte deraf
DK453181A (da) Fremgangsmaade til fremstilling af 2-quanidino-4-heteroaryl-thiazolforbindelser eller syreadditionssalte deraf
DK155792C (da) Analogifremgangsmaade til fremstilling af pyrrol-eddikesyreamider eller salte deraf
DK334581A (da) Fremgangsmaade til frmstilling af 9-amino-1-hydroxyotahydro-6h-benzo (c) quinolin-derivater eller syreadditionssalte deraf
DK413883D0 (da) Fremgangsmade til fremstilling af c-20-modificerede macrolid-derivater eller farmaceutisk acceptable salte deraf
DK144944C (da) Fremgangsmaade til fremstilling af d,1-5-methyltetrahydrofolinsyre eller salte deraf
DK358183D0 (da) Fremgangsmade til fremstilling af alfa-aryl-alkansyrer eller salte deraf
DK475982A (da) Fremgangsmaade til fremstilling af benzofuranoner eller salte deraf
DK495780A (da) Fremgangsmaade til fremstilling af 2-keto-l-gulonsyre eller salte deraf
DK365980A (da) Fremgangsmaade til fremstilling af 7-betaaminothiadiazolylacetylamino-3-cephem-4-carboxylsyreforbindelser eller salte deraf
DK155081A (da) Fremgangsmaade til fremstilling af 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaensyre eller salte heraf
DK211381A (da) Fremgangsmaade til fremstilling af carbapenam3-carboxylsyre- eller carbapen-2-em-3-carboxylsyre-forbindelser eller estere eller salte deraf
DK160043C (da) Analogifremgangsmaade til fremstilling af n-alk-2-en-4-yn-yl-benzothienylalkylaminer eller syreadditionssalte deraf
DK366081A (da) Fremgangsmaade til fremstilling af diaryl-imidazol-forbindelser eller salte deraf
DK161073C (da) Fremgangsmaade til fremstilling af 2-(2-amino-thiazol-4-yl)glyoxylsyrederivater eller salte heraf
DK152501C (da) Fremgangsmaade til fremstilling af pyrrolooe1,2-aaapyrimidiner eller salte deraf
DK432582A (da) Fremgangsmaade til fremstilling af aminooxazolylforbindelser eller salte deraf
DK208981A (da) Fremgangsmaade til fremstilling af benzoxazol- eller benzothiazol-2-carboxylsyreestere eller syreadditionssalte eller konjugatsalte deraf

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment