ES516556A0 - Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos. - Google Patents
Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos.Info
- Publication number
- ES516556A0 ES516556A0 ES516556A ES516556A ES516556A0 ES 516556 A0 ES516556 A0 ES 516556A0 ES 516556 A ES516556 A ES 516556A ES 516556 A ES516556 A ES 516556A ES 516556 A0 ES516556 A0 ES 516556A0
- Authority
- ES
- Spain
- Prior art keywords
- azaaralcanoil
- azaalcanoil
- carboxi
- carboxylics
- acides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20376980A | 1980-11-03 | 1980-11-03 | |
US23991881A | 1981-03-03 | 1981-03-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8401026A1 ES8401026A1 (es) | 1983-12-01 |
ES516556A0 true ES516556A0 (es) | 1983-12-01 |
Family
ID=26898886
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES506784A Expired ES8303329A1 (es) | 1980-11-03 | 1981-11-02 | Procedimiento para la obtencion de acidos 1-carboxi-(azaal- canoil o azaaralcanoil)-indolin-2-carboxilicos. |
ES516555A Expired ES8401025A1 (es) | 1980-11-03 | 1982-10-15 | Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos. |
ES516556A Granted ES516556A0 (es) | 1980-11-03 | 1982-10-15 | Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES506784A Expired ES8303329A1 (es) | 1980-11-03 | 1981-11-02 | Procedimiento para la obtencion de acidos 1-carboxi-(azaal- canoil o azaaralcanoil)-indolin-2-carboxilicos. |
ES516555A Expired ES8401025A1 (es) | 1980-11-03 | 1982-10-15 | Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0051301A1 (es) |
AU (1) | AU7702281A (es) |
CA (1) | CA1172258A (es) |
DD (1) | DD201888A5 (es) |
DK (1) | DK483681A (es) |
ES (3) | ES8303329A1 (es) |
FI (1) | FI813422L (es) |
GB (1) | GB2086390B (es) |
GR (1) | GR74689B (es) |
HU (1) | HU185324B (es) |
IL (1) | IL64185A0 (es) |
NO (1) | NO813694L (es) |
PT (1) | PT73916B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN156096B (es) * | 1981-03-19 | 1985-05-11 | Usv Pharma Corp | |
DE3226768A1 (de) * | 1981-11-05 | 1983-05-26 | Hoechst Ag, 6230 Frankfurt | Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
EP0170775B2 (de) * | 1981-12-29 | 1994-10-12 | Hoechst Aktiengesellschaft | Derivate bicyclischer Aminosäuren, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung sowie neue bicyclische Aminosäuren als Zwischenstufen und Verfahren zu deren Herstellung |
CA1341296C (en) * | 1981-12-29 | 2001-09-25 | Hansjorg Urbach | 2-azabicycloalkane-3-carboxylic acid derivatives, processes for their preparation, agents containing these compounds and their use |
DE3210496A1 (de) * | 1982-03-23 | 1983-10-06 | Hoechst Ag | Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung |
US4520205A (en) * | 1982-06-28 | 1985-05-28 | American Home Products Corporation | Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid |
US5175306A (en) * | 1983-01-31 | 1992-12-29 | Hoechst Aktiengesellschaft | Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters |
FR2546886B2 (fr) * | 1983-06-06 | 1986-05-16 | Adir | Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant |
DE3324263A1 (de) * | 1983-07-06 | 1985-01-17 | Hoechst Ag, 6230 Frankfurt | Derivate der 2-azabicyclo(3.1.0)hexan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(3.1.0)hexan-derivate als zwischenprodukte und verfahren zu deren herstellung |
DE3333454A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern |
DE3333455A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung n-alkylierter dipeptide und deren estern |
US5684016A (en) * | 1984-04-12 | 1997-11-04 | Hoechst Aktiengesellschaft | Method of treating cardiac insufficiency |
DE3413710A1 (de) * | 1984-04-12 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur behandlung der herzinsuffizienz |
DE3431541A1 (de) * | 1984-08-28 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung |
US5231080A (en) * | 1985-10-15 | 1993-07-27 | Hoechst Aktiengesellschaft | Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease |
US5231084A (en) * | 1986-03-27 | 1993-07-27 | Hoechst Aktiengesellschaft | Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons |
DE3633496A1 (de) * | 1986-10-02 | 1988-04-14 | Hoechst Ag | Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln |
DE3639879A1 (de) * | 1986-11-21 | 1988-06-01 | Hoechst Ag | Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung |
DE3722007A1 (de) * | 1987-07-03 | 1989-01-12 | Hoechst Ag | Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung |
TW197945B (es) * | 1990-11-27 | 1993-01-11 | Hoechst Ag | |
US5504080A (en) * | 1992-10-28 | 1996-04-02 | Bristol-Myers Squibb Co. | Benzo-fused lactams |
JPH09500113A (ja) * | 1993-06-30 | 1997-01-07 | チバ−ガイギー アクチェンゲゼルシャフト | エンケファリナーゼ及びaceのインヒビターとして有用な抗高血圧性三環式アゼピン誘導体 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
US4303583A (en) * | 1979-08-13 | 1981-12-01 | American Home Products Corporation | 1H,5H-[1,4]Thiazepino[4,3-a]indole-1,5-diones |
IE52663B1 (en) * | 1980-04-02 | 1988-01-20 | Warner Lambert Co | Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids |
-
1981
- 1981-10-29 GB GB8132559A patent/GB2086390B/en not_active Expired
- 1981-10-30 CA CA000389117A patent/CA1172258A/en not_active Expired
- 1981-10-30 FI FI813422A patent/FI813422L/fi not_active Application Discontinuation
- 1981-10-30 EP EP81109378A patent/EP0051301A1/de not_active Withdrawn
- 1981-11-02 PT PT73916A patent/PT73916B/pt unknown
- 1981-11-02 GR GR66399A patent/GR74689B/el unknown
- 1981-11-02 DK DK483681A patent/DK483681A/da not_active Application Discontinuation
- 1981-11-02 AU AU77022/81A patent/AU7702281A/en not_active Abandoned
- 1981-11-02 IL IL64185A patent/IL64185A0/xx unknown
- 1981-11-02 NO NO813694A patent/NO813694L/no unknown
- 1981-11-02 ES ES506784A patent/ES8303329A1/es not_active Expired
- 1981-11-02 HU HU813251A patent/HU185324B/hu unknown
- 1981-11-03 DD DD81234586A patent/DD201888A5/de unknown
-
1982
- 1982-10-15 ES ES516555A patent/ES8401025A1/es not_active Expired
- 1982-10-15 ES ES516556A patent/ES516556A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
IL64185A0 (en) | 1982-02-28 |
GB2086390A (en) | 1982-05-12 |
ES8401026A1 (es) | 1983-12-01 |
DD201888A5 (de) | 1983-08-17 |
ES506784A0 (es) | 1983-02-01 |
NO813694L (no) | 1982-05-04 |
GB2086390B (en) | 1984-06-06 |
PT73916B (en) | 1983-11-30 |
AU7702281A (en) | 1982-05-13 |
HU185324B (en) | 1985-01-28 |
FI813422L (fi) | 1982-05-04 |
EP0051301A1 (de) | 1982-05-12 |
ES8303329A1 (es) | 1983-02-01 |
PT73916A (en) | 1981-12-01 |
CA1172258A (en) | 1984-08-07 |
GR74689B (es) | 1984-07-03 |
DK483681A (da) | 1982-05-04 |
ES516555A0 (es) | 1983-12-01 |
ES8401025A1 (es) | 1983-12-01 |
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