CY1113028T1 - Φαρμακοτεχνικες μορφες σταθερου φαρμακευτικου διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης - Google Patents
Φαρμακοτεχνικες μορφες σταθερου φαρμακευτικου διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοηςInfo
- Publication number
- CY1113028T1 CY1113028T1 CY20121100369T CY121100369T CY1113028T1 CY 1113028 T1 CY1113028 T1 CY 1113028T1 CY 20121100369 T CY20121100369 T CY 20121100369T CY 121100369 T CY121100369 T CY 121100369T CY 1113028 T1 CY1113028 T1 CY 1113028T1
- Authority
- CY
- Cyprus
- Prior art keywords
- measuring pressure
- pharmaceutical
- pressure inhibition
- solution
- stable
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Μία σύνθεση αεροζόλ για χρήση σε μια συσκευή εισπνοής αεροζόλ περιλαμβάνει δραστικό υλικό, προωστικό που περιλαμβάνει υδροφθοροαλκάνιο, συνδιαλύτη και προαιρετικώς χαμηλής πτητικότητας συστατικό για να αυξάνεται η μέση αεροδυναμική διάμετρος μάζας (ΜΜΑD) των σωματιδίων του αεροζόλ κατά την ενεργοποίηση της συσκευής εισπνοής. Η σύνθεση είναι σταθεροποιημένη με χρήση μικρής ποσότητας ανοργάνου οξέος και ενός καταλλήλου περιέκτη που έχει τμήμα ή το σύνολο των μεταλλικών επιφανειών αυτού κατασκευασμένα από ανοξείδωτο χάλυβα, ανοδιωμένο αλουμίνιο ή είναι επενδυμένα με αδρανή οργανική επικάλυψη.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2000/004635 WO2001089480A1 (en) | 2000-05-22 | 2000-05-22 | Stable pharmaceutical solution formulations for pressurised metered dose inhalers |
EP10166800A EP2223682B1 (en) | 2000-05-22 | 2001-05-18 | Stable pharmaceutical solution formulations for pressurised metered dose inhalers |
Publications (1)
Publication Number | Publication Date |
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CY1113028T1 true CY1113028T1 (el) | 2016-04-13 |
Family
ID=8163952
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091100233T CY1108833T1 (el) | 2000-05-22 | 2009-02-27 | Σταθερες φαρμακευτικες φαρμακοτεχνικες μορφες διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY20091100391T CY1108968T1 (el) | 2000-05-22 | 2009-04-03 | Σταθερες φαρμακευτικες φαρμακοτεχνικες μορφες διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY2009009C CY2009009I1 (el) | 2000-05-22 | 2009-07-03 | Σταθερες φαρμακευτικες φαρμακοτεχνικες μορφες διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY20111100584T CY1111570T1 (el) | 2000-05-22 | 2011-06-20 | Φαρμακοτεχνικες μορφες σταθερου φαρμακευτικου διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY2011014C CY2011014I2 (el) | 2000-05-22 | 2011-09-22 | Φαρμακοτεχνικες μορφες σταθερου φαρμακευτικου διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY20121100369T CY1113028T1 (el) | 2000-05-22 | 2012-04-18 | Φαρμακοτεχνικες μορφες σταθερου φαρμακευτικου διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
Family Applications Before (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091100233T CY1108833T1 (el) | 2000-05-22 | 2009-02-27 | Σταθερες φαρμακευτικες φαρμακοτεχνικες μορφες διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY20091100391T CY1108968T1 (el) | 2000-05-22 | 2009-04-03 | Σταθερες φαρμακευτικες φαρμακοτεχνικες μορφες διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY2009009C CY2009009I1 (el) | 2000-05-22 | 2009-07-03 | Σταθερες φαρμακευτικες φαρμακοτεχνικες μορφες διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY20111100584T CY1111570T1 (el) | 2000-05-22 | 2011-06-20 | Φαρμακοτεχνικες μορφες σταθερου φαρμακευτικου διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
CY2011014C CY2011014I2 (el) | 2000-05-22 | 2011-09-22 | Φαρμακοτεχνικες μορφες σταθερου φαρμακευτικου διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης |
Country Status (41)
Country | Link |
---|---|
US (3) | US6716414B2 (el) |
EP (4) | EP1466594B1 (el) |
JP (1) | JP5392880B2 (el) |
CN (1) | CN1213732C (el) |
AR (1) | AR029523A1 (el) |
AT (4) | ATE502624T1 (el) |
AU (2) | AU5070100A (el) |
BE (1) | BE2011C032I2 (el) |
BG (1) | BG65883B1 (el) |
BR (1) | BR0015884A (el) |
CA (1) | CA2411047C (el) |
CY (6) | CY1108833T1 (el) |
CZ (1) | CZ303833B6 (el) |
DE (5) | DE60137282D1 (el) |
DK (4) | DK1787639T3 (el) |
DZ (1) | DZ3358A1 (el) |
EA (1) | EA005179B1 (el) |
EE (1) | EE05167B1 (el) |
ES (4) | ES2318217T3 (el) |
FR (1) | FR11C0041I2 (el) |
HK (1) | HK1058900A1 (el) |
HR (1) | HRP20021025B1 (el) |
HU (2) | HU230804B1 (el) |
IL (2) | IL152955A0 (el) |
JO (1) | JO2310B1 (el) |
LT (1) | LTC1787639I2 (el) |
LU (1) | LU91875I2 (el) |
ME (2) | ME00220B (el) |
MX (1) | MXPA02011414A (el) |
MY (2) | MY127145A (el) |
NL (1) | NL300393I2 (el) |
NO (3) | NO342935B1 (el) |
PE (1) | PE20011323A1 (el) |
PT (4) | PT1157689E (el) |
SA (1) | SA01220126B1 (el) |
SI (4) | SI1157689T1 (el) |
SK (1) | SK286694B6 (el) |
TN (1) | TNSN01074A1 (el) |
TW (1) | TWI284047B (el) |
UA (1) | UA73986C2 (el) |
WO (1) | WO2001089480A1 (el) |
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2003
- 2003-08-14 US US10/640,005 patent/US7018618B2/en not_active Expired - Lifetime
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2004
- 2004-03-12 HK HK04101816A patent/HK1058900A1/xx unknown
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2005
- 2005-05-22 ME MEP-321/08A patent/MEP32108A/xx unknown
- 2005-11-30 US US11/289,479 patent/US20060083693A1/en not_active Abandoned
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2009
- 2009-02-27 CY CY20091100233T patent/CY1108833T1/el unknown
- 2009-04-03 CY CY20091100391T patent/CY1108968T1/el unknown
- 2009-07-03 CY CY2009009C patent/CY2009009I1/el unknown
- 2009-07-03 NL NL300393C patent/NL300393I2/nl unknown
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2011
- 2011-06-20 CY CY20111100584T patent/CY1111570T1/el unknown
- 2011-09-20 DE DE201112100049 patent/DE122011100049I1/de active Pending
- 2011-09-20 BE BE2011C032C patent/BE2011C032I2/nl unknown
- 2011-09-20 LT LTPA2011011C patent/LTC1787639I2/lt unknown
- 2011-09-21 LU LU91875C patent/LU91875I2/fr unknown
- 2011-09-22 CY CY2011014C patent/CY2011014I2/el unknown
- 2011-09-23 FR FR11C0041C patent/FR11C0041I2/fr active Active
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2012
- 2012-04-18 CY CY20121100369T patent/CY1113028T1/el unknown
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2018
- 2018-07-13 HU HUS1800032C patent/HUS1800032I1/hu unknown
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2019
- 2019-01-16 NO NO2019003C patent/NO2019003I1/no unknown
- 2019-07-11 NO NO2019030C patent/NO2019030I1/no unknown
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