NO20010391L - Medisinske aerosolformuleringer - Google Patents

Medisinske aerosolformuleringer

Info

Publication number
NO20010391L
NO20010391L NO20010391A NO20010391A NO20010391L NO 20010391 L NO20010391 L NO 20010391L NO 20010391 A NO20010391 A NO 20010391A NO 20010391 A NO20010391 A NO 20010391A NO 20010391 L NO20010391 L NO 20010391L
Authority
NO
Norway
Prior art keywords
aerosol formulations
hydrofluoroalkanes
active compounds
pressure
dinitrogen monoxide
Prior art date
Application number
NO20010391A
Other languages
English (en)
Other versions
NO20010391D0 (no
Inventor
Manfred Keller
Kurt Herzog
Rudi Mueller-Walz
Holger Kraus
Original Assignee
Jago Res Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jago Res Ag filed Critical Jago Res Ag
Publication of NO20010391D0 publication Critical patent/NO20010391D0/no
Publication of NO20010391L publication Critical patent/NO20010391L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/124Aerosols; Foams characterised by the propellant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

En drivmiddelblanding som er gjort flytende under trykk for aerosoler, som innbefatter dinitrogenmonoksid og et hydrofluoralkan som har 1 til 3 karbonatomer, særlig 1,1,1,2-tetrafluoretan og/eller 1,1,1,2,3,3,3-heptafluorpropan, gjør mulig en forbedring i fukteegenskapene til farmasøytisk aktive forbindelser, hvorved formuleringsproblemene som eksisterer med hydrofluoralkaner kan bli overvunnet med hensyn til suspensjons-og løsningsaerosoler og således kan forbedrede medisinske aerosolformuleringer oppnås. Ved hjelp av dinitrogenmonoksid er det også mulig å influere trykket og således partikkelstørrelsesfordelingen særlig og, ved å erstatte oksygen fra hydrofluoralkanene, å forbedre lagringsstabliteten til oksydasjonssensitive aktive forbindelser. Hvis ønskelig, kan drivmiddelblandingen i tillegg inneholde karbondioksid.
NO20010391A 1998-07-24 2001-01-23 Medisinske aerosolformuleringer NO20010391L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH156598 1998-07-24
PCT/CH1999/000337 WO2000006121A1 (de) 1998-07-24 1999-07-22 Medizinische aerosolformulierungen

Publications (2)

Publication Number Publication Date
NO20010391D0 NO20010391D0 (no) 2001-01-23
NO20010391L true NO20010391L (no) 2001-03-23

Family

ID=4213402

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20010391A NO20010391L (no) 1998-07-24 2001-01-23 Medisinske aerosolformuleringer

Country Status (13)

Country Link
US (1) US6585958B1 (no)
EP (1) EP1100465B1 (no)
JP (1) JP4570251B2 (no)
CN (1) CN1158996C (no)
AT (1) ATE283033T1 (no)
AU (1) AU748867B2 (no)
CA (1) CA2338753C (no)
DE (1) DE59911149D1 (no)
ES (1) ES2234266T3 (no)
NO (1) NO20010391L (no)
NZ (1) NZ509328A (no)
WO (1) WO2000006121A1 (no)
ZA (1) ZA200100408B (no)

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Also Published As

Publication number Publication date
CN1312706A (zh) 2001-09-12
JP2002521424A (ja) 2002-07-16
CA2338753A1 (en) 2000-02-10
AU4598999A (en) 2000-02-21
CA2338753C (en) 2006-11-21
AU748867B2 (en) 2002-06-13
ATE283033T1 (de) 2004-12-15
NO20010391D0 (no) 2001-01-23
EP1100465A1 (de) 2001-05-23
WO2000006121A1 (de) 2000-02-10
ES2234266T3 (es) 2005-06-16
DE59911149D1 (de) 2004-12-30
US6585958B1 (en) 2003-07-01
NZ509328A (en) 2002-11-26
EP1100465B1 (de) 2004-11-24
ZA200100408B (en) 2001-09-26
JP4570251B2 (ja) 2010-10-27
CN1158996C (zh) 2004-07-28

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