JP7191099B2 - 浸漬管を備えた鼻腔内装置 - Google Patents
浸漬管を備えた鼻腔内装置 Download PDFInfo
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- YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 description 1
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- 239000007923 nasal drop Substances 0.000 description 1
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
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- A—HUMAN NECESSITIES
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- A61M15/00—Inhalators
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- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
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- A61M15/00—Inhalators
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B9/00—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour
- B05B9/03—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material
- B05B9/04—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material with pressurised or compressible container; with pump
- B05B9/08—Apparatus to be carried on or by a person, e.g. of knapsack type
- B05B9/0805—Apparatus to be carried on or by a person, e.g. of knapsack type comprising a pressurised or compressible container for liquid or other fluent material
- B05B9/0833—Apparatus to be carried on or by a person, e.g. of knapsack type comprising a pressurised or compressible container for liquid or other fluent material comprising a compressed gas container, e.g. a nitrogen cartridge
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B9/00—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour
- B05B9/03—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material
- B05B9/04—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material with pressurised or compressible container; with pump
- B05B9/08—Apparatus to be carried on or by a person, e.g. of knapsack type
- B05B9/0805—Apparatus to be carried on or by a person, e.g. of knapsack type comprising a pressurised or compressible container for liquid or other fluent material
- B05B9/0838—Apparatus to be carried on or by a person, e.g. of knapsack type comprising a pressurised or compressible container for liquid or other fluent material supply being effected by follower in container, e.g. membrane or floating piston, or by deformation of container
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
Description
本開示の実施形態の前述の説明は、例示の目的で提示されている。網羅的であること、または開示された正確な態様に限定することは意図されていない。関連技術分野における当業者は、上記の開示に照らして多くの修正および変形が可能であることを理解することができる。
Claims (17)
- 鼻腔の嗅覚領域に化合物を送達するための装置において、
推進剤を含むキャニスターと流体連通するように構成された推進剤チャネルを備えたアクチュエーター本体と、および
前記アクチュエーター本体に取り外し可能に結合するように構成された先端であって、
空洞と開口部を備える先端ステムであって、前記空洞は前記推進剤チャネルと流体連通し、前記空洞は化合物を含む化合物容器を受け入れるように構成され、前記化合物容器は、前記空洞内の密閉状態と非密閉状態との間を移動するように構成された、先端ステムと、
前記空洞内に配置された浸漬管であって、前記浸漬管の近位端から遠位端まで延在する送達チャネルを備える浸漬管と、
前記化合物容器を穿刺するようにそれぞれが構成された1つまたは複数の穿刺部材であって、前記穿刺された化合物容器が前記推進剤チャネルおよび前記送達チャネルと流体連通している、1つまたは複数の穿刺部材と、
前記浸漬管の前記近位端から前記送達チャネルと流体連通している流出口であって、前記キャニスターから放出された前記推進剤は、前記推進剤チャネルを通って前記空洞に入り、化合物容器に入り、それにより、化合物に接触し、前記送達チャネルと前記流出口を通して化合物を推進する、流出口と、
前記先端内の前記浸漬管の前記近位端に配置されたカラーであって、1つまたは複数のバイパス開口部を備え、前記1つまたは複数のバイパス開口部は、放出された前記推進剤が前記化合物容器に導入されるように前記推進剤チャネルと流体連通する、カラーと、
を備える先端と、を備え、
前記先端ステムの前記開口部は、前記アクチュエーター本体の内面と合わさるように構成される、ことを特徴とする装置。 - 前記少なくとも1つの穿刺部材が、前記浸漬管の前記遠位端に配置されていることを特徴とする、請求項1に記載の装置。
- 前記カラーが前記浸漬管の一部の周りに結合し、少なくとも1つの穿刺部材が前記カラーに配置されることを特徴とする、請求項1に記載の装置。
- 少なくとも1つの穿刺部材が前記浸漬管の前記遠位端に配置され、前記少なくとも1つの穿刺部材は、最初に前記化合物容器を穿刺するように構成され、前記カラー上に配置されている前記少なくとも1つの穿刺部材は、前記化合物容器が前記非密閉状態にあるときに、前記化合物容器を2番目に穿刺するように構成されていることを特徴とする請求項3に記載の装置。
- 前記先端ステムと結合するように構成された先端コーンをさらに備え、前記先端コーンはユーザの鼻孔と前記装置が揃うように構成されていることを特徴とする、請求項1に記載の装置。
- 前記先端コーンは、前記ユーザの鼻孔への挿入量の深さを示すように構成された深さ停止ガードを備えることを特徴とする、請求項5に記載の装置。
- 前記送達チャネルと前記流出口とに流体連通しているノズルをさらに備え、前記ノズルは、1つまたは複数のチャネルを含むことを特徴とする、請求項1に記載の装置。
- 前記先端と前記アクチュエーター本体との間の密閉界面をさらに備えたことを特徴とする、請求項1に記載の装置。
- 前記化合物容器がプラスチックフィルムから構成されることを特徴とする、請求項1に記載の装置。
- 前記アクチュエーター本体は、作動されると、前記先端を前記アクチュエーター本体から切り離すように構成される解放ボタンを備えることを特徴とする、請求項1に記載の装置。
- 前記解放ボタンは、前記先端の1つ以上の開口部と嵌合するように構成され、それにより前記先端を前記アクチュエーター本体に結合する1つ以上のクリップ機構に接続されることを特徴とする、請求項10に記載の装置。
- 前記先端ステムの開口部は、前記アクチュエーター本体の内面上に相互リブを受け入れるように構成され、前記相互リブは、前記先端が前記アクチュエーター本体に挿入されると、前記空洞内の前記化合物容器を前記密閉状態から前記非密閉状態に移動するように構成されることを特徴とする、請求項1に記載の装置。
- 前記化合物容器を収容するように構成されたシャトルをさらに備え、前記シャトルは前記空洞内に挿入されることを特徴とする、請求項1に記載の装置。
- 前記シャトルは、前記密閉状態と前記非密閉状態との間を移動するための剛体を提供するように構成される、請求項13に記載の装置。
- 前記シャトルは、前記空洞への挿入時に前記シャトルの向きを示すように構成された1つ以上の広がったリップを備えることを特徴とする、請求項13に記載の装置。
- 前記化合物が液体であることを特徴とする、請求項1に記載の装置。
- 前記カラーは、1つまたは複数のバイパス開口部によって囲まれた中央開口部を備え、前記中央開口部は、前記浸漬管に適合するように構成される、請求項1に記載の装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201762589306P | 2017-11-21 | 2017-11-21 | |
US62/589,306 | 2017-11-21 | ||
PCT/US2018/062296 WO2019104205A1 (en) | 2017-11-21 | 2018-11-21 | Intranasal device with dip tube |
Publications (3)
Publication Number | Publication Date |
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JP2021503989A JP2021503989A (ja) | 2021-02-15 |
JP2021503989A5 JP2021503989A5 (ja) | 2021-10-14 |
JP7191099B2 true JP7191099B2 (ja) | 2022-12-16 |
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JP2020528005A Active JP7191099B2 (ja) | 2017-11-21 | 2018-11-21 | 浸漬管を備えた鼻腔内装置 |
Country Status (4)
Country | Link |
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US (1) | US11571532B2 (ja) |
EP (1) | EP3713628A4 (ja) |
JP (1) | JP7191099B2 (ja) |
WO (1) | WO2019104205A1 (ja) |
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Publication number | Priority date | Publication date | Assignee | Title |
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BR112021013244A8 (pt) * | 2019-01-03 | 2022-10-18 | Impel Neuropharma Inc | Dispositivo de entrega de fármaco nasal |
WO2022049103A2 (en) * | 2020-09-01 | 2022-03-10 | Janssen Pharmaceutica Nv | Drug delivery devices with reusable components and disposable components |
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WO2019104205A1 (en) | 2019-05-31 |
US11571532B2 (en) | 2023-02-07 |
EP3713628A4 (en) | 2021-08-18 |
JP2021503989A (ja) | 2021-02-15 |
EP3713628A1 (en) | 2020-09-30 |
US20190151579A1 (en) | 2019-05-23 |
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