CS227012B2 - Method of preparing 2-amino-3-benzoyl-phenylacetamide - Google Patents
Method of preparing 2-amino-3-benzoyl-phenylacetamide Download PDFInfo
- Publication number
- CS227012B2 CS227012B2 CS806196A CS619680A CS227012B2 CS 227012 B2 CS227012 B2 CS 227012B2 CS 806196 A CS806196 A CS 806196A CS 619680 A CS619680 A CS 619680A CS 227012 B2 CS227012 B2 CS 227012B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- amino
- solution
- mol
- added
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7886079A | 1979-09-26 | 1979-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CS227012B2 true CS227012B2 (en) | 1984-04-16 |
Family
ID=22146633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS806196A CS227012B2 (en) | 1979-09-26 | 1980-09-11 | Method of preparing 2-amino-3-benzoyl-phenylacetamide |
Country Status (36)
Country | Link |
---|---|
JP (1) | JPS5657751A (sv) |
KR (1) | KR840000763B1 (sv) |
AT (1) | AT374170B (sv) |
AU (1) | AU532359B2 (sv) |
BE (1) | BE885393A (sv) |
BR (1) | BR8006042A (sv) |
CA (1) | CA1128512A (sv) |
CH (1) | CH646138A5 (sv) |
CS (1) | CS227012B2 (sv) |
DE (1) | DE3035688A1 (sv) |
DK (1) | DK154136C (sv) |
EG (1) | EG15020A (sv) |
ES (2) | ES495329A0 (sv) |
FI (1) | FI72967C (sv) |
FR (1) | FR2465710A1 (sv) |
GB (1) | GB2059963B (sv) |
GR (1) | GR70049B (sv) |
HK (1) | HK59383A (sv) |
HU (1) | HU183215B (sv) |
IE (1) | IE50268B1 (sv) |
IL (1) | IL60999A (sv) |
IN (3) | IN151313B (sv) |
IT (1) | IT1133823B (sv) |
KE (1) | KE3307A (sv) |
LU (1) | LU82797A1 (sv) |
MX (1) | MX7159E (sv) |
NL (1) | NL8005346A (sv) |
NO (1) | NO152128C (sv) |
NZ (1) | NZ195061A (sv) |
PH (1) | PH22628A (sv) |
PL (1) | PL128998B1 (sv) |
PT (1) | PT71839B (sv) |
SE (1) | SE448626B (sv) |
SG (1) | SG42983G (sv) |
YU (3) | YU41734B (sv) |
ZA (1) | ZA805476B (sv) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
US6066671A (en) * | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
US6646001B2 (en) | 1997-12-19 | 2003-11-11 | Alcon Manufacturing, Ltd. | Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension |
GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
JP4350508B2 (ja) | 2001-09-03 | 2009-10-21 | ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー | ガバペンチンまたはその類似体とα−アミノアミドとを含む薬剤組成物およびその鎮痛用途 |
EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
CZ301776B6 (cs) * | 2009-06-08 | 2010-06-16 | Farmak, A.S. | Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu |
CN112794809B (zh) * | 2019-11-14 | 2023-12-29 | 南京济群医药科技股份有限公司 | 一种高纯度奈帕芬胺中间体的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1226344A (sv) * | 1967-07-31 | 1971-03-24 | ||
CH577461A5 (sv) * | 1975-08-13 | 1976-07-15 | Robins Co Inc A H | |
IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
-
1980
- 1980-09-04 ZA ZA00805476A patent/ZA805476B/xx unknown
- 1980-09-08 AU AU62116/80A patent/AU532359B2/en not_active Ceased
- 1980-09-08 IL IL60999A patent/IL60999A/xx unknown
- 1980-09-11 CS CS806196A patent/CS227012B2/cs unknown
- 1980-09-17 IE IE1946/80A patent/IE50268B1/en unknown
- 1980-09-20 EG EG80573A patent/EG15020A/xx active
- 1980-09-22 GR GR62936A patent/GR70049B/el unknown
- 1980-09-22 DE DE19803035688 patent/DE3035688A1/de active Granted
- 1980-09-22 BR BR8006042A patent/BR8006042A/pt unknown
- 1980-09-23 AT AT0474580A patent/AT374170B/de not_active IP Right Cessation
- 1980-09-23 PH PH24613A patent/PH22628A/en unknown
- 1980-09-24 LU LU82797A patent/LU82797A1/fr unknown
- 1980-09-24 SE SE8006668A patent/SE448626B/sv not_active IP Right Cessation
- 1980-09-24 FI FI803002A patent/FI72967C/sv not_active IP Right Cessation
- 1980-09-25 ES ES495329A patent/ES495329A0/es active Granted
- 1980-09-25 PL PL1980226919A patent/PL128998B1/pl unknown
- 1980-09-25 DK DK405780A patent/DK154136C/da not_active IP Right Cessation
- 1980-09-25 YU YU2450/80A patent/YU41734B/xx unknown
- 1980-09-25 CA CA361,068A patent/CA1128512A/en not_active Expired
- 1980-09-25 HU HU802347A patent/HU183215B/hu not_active IP Right Cessation
- 1980-09-25 NO NO802834A patent/NO152128C/no unknown
- 1980-09-25 PT PT71839A patent/PT71839B/pt unknown
- 1980-09-25 BE BE0/202226A patent/BE885393A/fr not_active IP Right Cessation
- 1980-09-25 MX MX809050U patent/MX7159E/es unknown
- 1980-09-25 CH CH719180A patent/CH646138A5/fr not_active IP Right Cessation
- 1980-09-25 FR FR8020596A patent/FR2465710A1/fr active Granted
- 1980-09-25 KR KR1019800003740A patent/KR840000763B1/ko active
- 1980-09-25 GB GB8030955A patent/GB2059963B/en not_active Expired
- 1980-09-25 NL NL8005346A patent/NL8005346A/nl not_active Application Discontinuation
- 1980-09-26 NZ NZ195061A patent/NZ195061A/en unknown
- 1980-09-26 IT IT24948/80A patent/IT1133823B/it active
- 1980-09-26 IN IN1092/CAL/80A patent/IN151313B/en unknown
- 1980-09-26 JP JP13415280A patent/JPS5657751A/ja active Granted
-
1981
- 1981-06-12 ES ES503019A patent/ES8204715A1/es not_active Expired
-
1982
- 1982-12-30 IN IN1509/CAL/82A patent/IN156255B/en unknown
- 1982-12-30 IN IN1508/CAL/82A patent/IN156254B/en unknown
-
1983
- 1983-03-28 YU YU731/83A patent/YU43306B/xx unknown
- 1983-03-28 YU YU730/83A patent/YU43305B/xx unknown
- 1983-07-19 SG SG42983A patent/SG42983G/en unknown
- 1983-07-21 KE KE3307A patent/KE3307A/xx unknown
- 1983-11-24 HK HK593/83A patent/HK59383A/xx unknown
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