CS222698B2 - Method of preparation of the new indolizine derivatives - Google Patents

Method of preparation of the new indolizine derivatives Download PDF

Info

Publication number
CS222698B2
CS222698B2 CS814016A CS401680A CS222698B2 CS 222698 B2 CS222698 B2 CS 222698B2 CS 814016 A CS814016 A CS 814016A CS 401680 A CS401680 A CS 401680A CS 222698 B2 CS222698 B2 CS 222698B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
methyl
indolizine
oxy
solvent
Prior art date
Application number
CS814016A
Other languages
Czech (cs)
English (en)
Inventor
Gilbert Rosseels
Wmmel Union-Henri
Original Assignee
Labaz Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz Nv filed Critical Labaz Nv
Publication of CS222698B2 publication Critical patent/CS222698B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CS814016A 1979-12-06 1980-12-04 Method of preparation of the new indolizine derivatives CS222698B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7942146 1979-12-06

Publications (1)

Publication Number Publication Date
CS222698B2 true CS222698B2 (en) 1983-07-29

Family

ID=10509659

Family Applications (3)

Application Number Title Priority Date Filing Date
CS808517A CS222697B2 (en) 1979-12-06 1980-12-04 Method of preparation of the new indoline derivatives
CS808517A CS222692B2 (en) 1979-12-06 1980-12-04 Method of preparation of the new indolizine derivatives
CS814016A CS222698B2 (en) 1979-12-06 1980-12-04 Method of preparation of the new indolizine derivatives

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CS808517A CS222697B2 (en) 1979-12-06 1980-12-04 Method of preparation of the new indoline derivatives
CS808517A CS222692B2 (en) 1979-12-06 1980-12-04 Method of preparation of the new indolizine derivatives

Country Status (40)

Country Link
JP (1) JPS56103181A (ro)
AR (4) AR227036A1 (ro)
AT (1) AT376438B (ro)
AU (1) AU536320B2 (ro)
BE (1) BE886511A (ro)
BG (2) BG35598A3 (ro)
BR (1) BR8007691A (ro)
CA (1) CA1152077A (ro)
CH (1) CH651041A5 (ro)
CS (3) CS222697B2 (ro)
DD (1) DD155069A5 (ro)
DE (1) DE3046017C2 (ro)
DK (1) DK146977C (ro)
ES (4) ES497504A0 (ro)
FI (1) FI67846C (ro)
GR (1) GR70224B (ro)
HK (1) HK65884A (ro)
HU (1) HU185019B (ro)
IE (1) IE50519B1 (ro)
IL (1) IL61385A (ro)
IN (1) IN151241B (ro)
IS (1) IS1209B6 (ro)
IT (1) IT1218424B (ro)
KE (1) KE3438A (ro)
LU (1) LU82983A1 (ro)
MA (1) MA19007A1 (ro)
NL (1) NL184683C (ro)
NO (1) NO157019C (ro)
NZ (1) NZ195754A (ro)
OA (1) OA06711A (ro)
PH (1) PH17028A (ro)
PL (3) PL127999B1 (ro)
PT (1) PT72151B (ro)
RO (3) RO81452B (ro)
SE (1) SE441926B (ro)
SG (1) SG33384G (ro)
SU (3) SU1058505A3 (ro)
YU (3) YU42366B (ro)
ZA (1) ZA806831B (ro)
ZW (1) ZW28580A1 (ro)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10065955B2 (en) * 2014-12-10 2018-09-04 Ono Pharmaceutical Co., Ltd. Dihydroindolizinone derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1518443A (en) 1976-02-19 1978-07-19 Labaz Indolizine derivatives and process for preparing the same

Also Published As

Publication number Publication date
CH651041A5 (en) 1985-08-30
RO85271A (ro) 1984-09-29
DD155069A5 (de) 1982-05-12
ES8205798A1 (es) 1982-06-16
YU42366B (en) 1988-08-31
ES8300109A1 (es) 1982-10-01
PL129365B1 (en) 1984-05-31
IL61385A (en) 1984-11-30
SU1109051A3 (ru) 1984-08-15
NL8006310A (nl) 1981-07-01
BR8007691A (pt) 1981-06-09
AU536320B2 (en) 1984-05-03
ZA806831B (en) 1981-10-28
CA1152077A (en) 1983-08-16
YU44383A (en) 1983-10-31
NZ195754A (en) 1984-03-16
SE8008444L (sv) 1981-06-07
BG37379A3 (en) 1985-05-15
HU185019B (en) 1984-11-28
AR227094A1 (es) 1982-09-15
ES508053A0 (es) 1982-10-01
DK146977B (da) 1984-03-05
CS222697B2 (en) 1983-07-29
DK146977C (da) 1984-08-13
RO81452A (ro) 1983-04-29
HK65884A (en) 1984-08-31
JPS6325591B2 (ro) 1988-05-26
ES508052A0 (es) 1982-10-01
PT72151A (en) 1981-01-01
ES8300110A1 (es) 1982-10-01
IE50519B1 (en) 1986-04-30
CS222692B2 (en) 1983-07-29
PL228265A1 (ro) 1981-11-13
SG33384G (en) 1985-02-08
ATA596780A (de) 1984-04-15
RO81452B (ro) 1983-04-30
AR227036A1 (es) 1982-09-15
SE441926B (sv) 1985-11-18
YU42127B (en) 1988-04-30
JPS56103181A (en) 1981-08-18
IL61385A0 (en) 1980-12-31
FI803792L (fi) 1981-06-07
YU42840B (en) 1988-12-31
RO84707A (ro) 1984-07-17
AT376438B (de) 1984-11-26
PL231828A1 (ro) 1982-03-15
IT1218424B (it) 1990-04-19
DK521980A (da) 1981-06-07
BG35598A3 (en) 1984-05-15
YU304180A (en) 1983-10-31
ES508051A0 (es) 1982-10-01
ZW28580A1 (en) 1981-08-26
IE802520L (en) 1981-06-06
AR229692A1 (es) 1983-10-31
SU1058505A3 (ru) 1983-11-30
FI67846C (fi) 1985-06-10
ES8300108A1 (es) 1982-10-01
YU44483A (en) 1983-10-31
NO803681L (no) 1981-06-09
MA19007A1 (fr) 1981-07-01
DE3046017C2 (de) 1986-09-25
IT8026463A0 (it) 1980-12-05
SU1287751A3 (ru) 1987-01-30
LU82983A1 (fr) 1981-03-26
PT72151B (en) 1981-10-28
GR70224B (ro) 1982-08-31
NO157019B (no) 1987-09-28
DE3046017A1 (de) 1981-09-03
RO85271B (ro) 1984-10-30
PL127999B1 (en) 1983-12-31
OA06711A (fr) 1982-06-30
ES497504A0 (es) 1982-06-16
AU6429280A (en) 1981-06-11
KE3438A (en) 1984-08-24
AR227093A1 (es) 1982-09-15
IS1209B6 (is) 1986-03-24
RO84707B (ro) 1984-09-30
IN151241B (ro) 1983-03-12
IS2594A7 (is) 1981-06-07
PL127865B1 (en) 1983-12-31
NO157019C (no) 1988-01-06
NL184683C (nl) 1989-10-02
FI67846B (fi) 1985-02-28
NL184683B (nl) 1989-05-01
PL231829A1 (ro) 1982-03-15
BE886511A (fr) 1981-06-05
PH17028A (en) 1984-05-17

Similar Documents

Publication Publication Date Title
Rinehart Jr et al. Eudistomins AQ,. beta.-carbolines from the antiviral Caribbean tunicate Eudistoma olivaceum
TW200403224A (en) Novel compounds
NO118710B (ro)
CS390691A3 (en) Olefinic 1h-imidazo-(4,5-c)quinolin-4-amines
WO2004039782A1 (ja) Ｆｌｔ３自己リン酸化を阻害するキノリン誘導体およびキナゾリン誘導体並びにそれらを含有する医薬組成物
PL188908B1 (pl) Nowe pochodne benzimidazolu i ich zastosowanie dowytwarzania leków do leczenia stanów alergicznych
NO162176B (no) Middel for bekjempelse av plantesykdommer og anvendelse derav.
MXPA02006499A (es) Derivados de fenilpiperazinilo.
PT96891A (pt) Processo para a preparacao de novos derivados de aminometilpiperidina
CA1115703A (en) Piperidinopropyl derivatives
AU606778B2 (en) Derivatives of 2-{(4-piperidinyl)methyl}-1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
PT94151B (pt) Processo para a preparacao de dihidrodibenzotiazepinas uteis como agentes antiespasmodicos
WO1983000865A1 (en) Benzothiazoline compounds
US5008264A (en) N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents
CS222698B2 (en) Method of preparation of the new indolizine derivatives
US3309370A (en) Bicycloalkyl piperazine derivatives and process
US5030639A (en) N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents
US2534774A (en) Piperazine derivatives
US4454139A (en) α2 -Adrenoceptor antagonistic benzoquinolizines
JPH02240053A (ja) アミノアルコキシフェニル誘導体、その製法およびそれを含有する組成物
CS248020B2 (en) Production method of the (+)-enantiomere or (+-)-racemical 4a,9b-trans-hexahydro-1h-pyridoindole derivatives
PT87116B (pt) Processo para a preparacao de derivados de nitroeteno
SU428602A3 (ru) Способ получения основпозамещенных производных 1
EA025216B1 (ru) Производное 5-замещенной индол-3-карбоновой кислоты, обладающее противовирусным действием в отношении вируса гриппа а
JP2014051463A (ja) Ｌｓｔ−１及び／又はｌｓｔ−２によって輸送される化合物