CS209855B2 - Method of making the new aminoacids derivatives - Google Patents
Method of making the new aminoacids derivatives Download PDFInfo
- Publication number
- CS209855B2 CS209855B2 CS752987A CS298775A CS209855B2 CS 209855 B2 CS209855 B2 CS 209855B2 CS 752987 A CS752987 A CS 752987A CS 298775 A CS298775 A CS 298775A CS 209855 B2 CS209855 B2 CS 209855B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- group
- formula
- compounds
- hydrogen
- alkoxy
- Prior art date
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- 238000004519 manufacturing process Methods 0.000 title description 7
- 235000001014 amino acid Nutrition 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 24
- 239000001257 hydrogen Substances 0.000 claims abstract description 22
- 150000003839 salts Chemical class 0.000 claims abstract description 22
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims abstract description 17
- 229910052736 halogen Inorganic materials 0.000 claims abstract description 16
- 150000002367 halogens Chemical class 0.000 claims abstract description 16
- 150000002431 hydrogen Chemical class 0.000 claims abstract description 16
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 14
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract description 13
- -1 hydroxy, amino Chemical group 0.000 claims abstract description 8
- 125000003545 alkoxy group Chemical group 0.000 claims abstract description 7
- 150000003862 amino acid derivatives Chemical class 0.000 claims abstract description 4
- 125000005518 carboxamido group Chemical group 0.000 claims abstract description 3
- 125000000000 cycloalkoxy group Chemical group 0.000 claims abstract description 3
- 150000001875 compounds Chemical class 0.000 claims description 89
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 49
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 37
- 238000000034 method Methods 0.000 claims description 28
- 238000002360 preparation method Methods 0.000 claims description 26
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 claims description 24
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- 125000006239 protecting group Chemical group 0.000 claims description 16
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 claims description 13
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- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 12
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 12
- 229910000042 hydrogen bromide Inorganic materials 0.000 claims description 12
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Substances [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 11
- 238000009903 catalytic hydrogenation reaction Methods 0.000 claims description 9
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 8
- 125000004432 carbon atom Chemical group C* 0.000 claims description 8
- 238000007327 hydrogenolysis reaction Methods 0.000 claims description 8
- 125000006678 phenoxycarbonyl group Chemical group 0.000 claims description 8
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 8
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- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 claims description 7
- 229910052763 palladium Inorganic materials 0.000 claims description 6
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- 239000003054 catalyst Substances 0.000 claims description 4
- 238000003776 cleavage reaction Methods 0.000 claims description 4
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- 230000007017 scission Effects 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- 239000007858 starting material Substances 0.000 claims description 3
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- 125000002030 1,2-phenylene group Chemical group [H]C1=C([H])C([*:1])=C([*:2])C([H])=C1[H] 0.000 abstract 1
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- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Birds (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU74FE00000928A HU171576B (hu) | 1974-04-29 | 1974-04-29 | Sposob otdelenija gamma-l-glutamil-taurina |
| HU74CI1558A HU174114B (hu) | 1975-03-26 | 1975-03-26 | Sposob poluchenija novykh proizvodnykh aminokislot |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS209855B2 true CS209855B2 (en) | 1981-12-31 |
Family
ID=26318406
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS752987A CS209855B2 (en) | 1974-04-29 | 1975-04-29 | Method of making the new aminoacids derivatives |
| CS786130A CS209858B2 (en) | 1974-04-29 | 1978-09-22 | Method of making the new derivatives of the aminoacids |
| CS786129A CS209857B2 (en) | 1974-04-29 | 1978-09-22 | Method of making the new derivatives of the aminoacids |
| CS786128A CS209856B2 (en) | 1974-04-29 | 1978-09-22 | Method of making the new derivatives of the aminoacids |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS786130A CS209858B2 (en) | 1974-04-29 | 1978-09-22 | Method of making the new derivatives of the aminoacids |
| CS786129A CS209857B2 (en) | 1974-04-29 | 1978-09-22 | Method of making the new derivatives of the aminoacids |
| CS786128A CS209856B2 (en) | 1974-04-29 | 1978-09-22 | Method of making the new derivatives of the aminoacids |
Country Status (23)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU178199B (en) * | 1976-05-06 | 1982-03-28 | Chinoin Gyogyszer Es Vegyeszet | New process for producing amides of omega-amino-carboxylic acids |
| HU180443B (en) * | 1979-04-02 | 1983-03-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing a pharmaceutical preparation with synergetic action against radiation |
| HU185632B (en) * | 1981-03-27 | 1985-03-28 | Chinoin Gyogyszer Es Vegyeszet | New process for preparing gamma-glutamyl-taurine |
| CH665645A5 (fr) * | 1981-07-09 | 1988-05-31 | Michel Flork | Derives de dipeptides et leur procede de preparation. |
| HU208072B (en) * | 1990-02-28 | 1993-08-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical composition suitable for preventing and curing autoimmune diseases and skin affections caused by heat and light radiacion |
| JPH0680964A (ja) * | 1991-12-27 | 1994-03-22 | Sogo Yatsukou Kk | 活性酸素消去剤 |
| JPH11180846A (ja) * | 1997-12-15 | 1999-07-06 | Sogo Pharmaceut Co Ltd | 化粧料 |
| DE10133197A1 (de) * | 2001-07-07 | 2003-01-23 | Beiersdorf Ag | Aminosäuren enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut |
| KR101443573B1 (ko) | 2006-10-12 | 2014-11-03 | 비에이치아이 리미티드 파트너쉽 | 3-아미노-1-프로판설폰산을 전달하기 위한 방법, 화합물, 조성물 및 비히클 |
| US9662304B1 (en) * | 2013-06-13 | 2017-05-30 | Thermolife International, Llc | Substituted glutaurine compounds and substituted glutaurine derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU169462B (US07534539-20090519-C00280.png) * | 1971-08-04 | 1976-11-28 |
-
1975
- 1975-04-23 IL IL47149A patent/IL47149A/xx unknown
- 1975-04-24 AT AT314075A patent/AT361902B/de not_active IP Right Cessation
- 1975-04-24 DE DE19752518160 patent/DE2518160A1/de active Granted
- 1975-04-24 DE DE2559989A patent/DE2559989C3/de not_active Expired
- 1975-04-25 FI FI751256A patent/FI65990C/fi not_active IP Right Cessation
- 1975-04-25 ES ES436986A patent/ES436986A1/es not_active Expired
- 1975-04-25 SE SE7504828A patent/SE430164B/xx not_active IP Right Cessation
- 1975-04-28 NO NO751504A patent/NO146430C/no unknown
- 1975-04-28 GB GB17608/75A patent/GB1504541A/en not_active Expired
- 1975-04-28 AU AU80564/75A patent/AU499173B2/en not_active Expired
- 1975-04-28 DD DD193288A patent/DD125070A5/xx unknown
- 1975-04-28 DD DD185727A patent/DD122377A5/xx unknown
- 1975-04-28 CA CA225,659A patent/CA1051802A/en not_active Expired
- 1975-04-28 EG EG262/75A patent/EG11847A/xx active
- 1975-04-28 FR FR7513230A patent/FR2279388A1/fr active Granted
- 1975-04-28 CH CH539075A patent/CH617183A5/de not_active IP Right Cessation
- 1975-04-28 SU SU752128794A patent/SU747419A3/ru active
- 1975-04-28 DK DK182875A patent/DK155433C/da not_active IP Right Cessation
- 1975-04-29 BG BG030769A patent/BG26517A4/xx unknown
- 1975-04-29 NL NLAANVRAGE7505075,A patent/NL183186C/xx not_active IP Right Cessation
- 1975-04-29 BE BE155914A patent/BE828546A/xx not_active IP Right Cessation
- 1975-04-29 BG BG030768A patent/BG26369A4/xx unknown
- 1975-04-29 BG BG030770A patent/BG26370A4/xx unknown
- 1975-04-29 BG BG029816A patent/BG26368A3/xx unknown
- 1975-04-29 CS CS752987A patent/CS209855B2/cs unknown
- 1975-04-29 PL PL1975196798A patent/PL111746B1/pl unknown
- 1975-04-29 PL PL1975196801A patent/PL111745B1/pl unknown
- 1975-04-30 JP JP50051612A patent/JPS6012347B2/ja not_active Expired
-
1976
- 1976-04-02 AR AR262769A patent/AR217236A1/es active
- 1976-04-02 AR AR262768A patent/AR218221A1/es active
- 1976-04-02 AR AR262770A patent/AR218222A1/es active
- 1976-11-13 ES ES453305A patent/ES453305A1/es not_active Expired
- 1976-11-13 ES ES453304A patent/ES453304A1/es not_active Expired
- 1976-11-13 ES ES453306A patent/ES453306A1/es not_active Expired
-
1977
- 1977-08-30 AT AT624777A patent/AT359084B/de not_active Expired
- 1977-08-30 AT AT624877A patent/AT359085B/de not_active IP Right Cessation
- 1977-08-30 AT AT624977A patent/AT351007B/de not_active IP Right Cessation
- 1977-10-06 DK DK442777A patent/DK442777A/da not_active Application Discontinuation
- 1977-10-06 DK DK442677A patent/DK159654C/da not_active IP Right Cessation
- 1977-10-06 DK DK443077A patent/DK159267C/da not_active IP Right Cessation
- 1977-10-06 DK DK442577A patent/DK442577A/da not_active Application Discontinuation
- 1977-10-06 DK DK442877A patent/DK158676C/da active
- 1977-10-06 DK DK442977A patent/DK442977A/da unknown
- 1977-10-06 DK DK442477A patent/DK155732C/da not_active IP Right Cessation
- 1977-10-06 DK DK442377A patent/DK155520C/da not_active IP Right Cessation
-
1978
- 1978-09-22 CS CS786130A patent/CS209858B2/cs unknown
- 1978-09-22 CS CS786129A patent/CS209857B2/cs unknown
- 1978-09-22 CS CS786128A patent/CS209856B2/cs unknown
- 1978-12-14 SE SE7812884A patent/SE441356B/sv not_active IP Right Cessation
-
1979
- 1979-04-30 AT AT0323079A patent/AT374484B/de not_active IP Right Cessation
- 1979-04-30 AT AT0323179A patent/AT370724B/de not_active IP Right Cessation
- 1979-10-19 CH CH943279A patent/CH621334A5/de not_active IP Right Cessation
- 1979-10-19 CH CH943379A patent/CH624098A5/de not_active IP Right Cessation
- 1979-10-19 CH CH943179A patent/CH621333A5/de not_active IP Right Cessation
-
1981
- 1981-03-10 NO NO810816A patent/NO149036C/no unknown
-
1983
- 1983-05-31 DK DK245783A patent/DK155672C/da not_active IP Right Cessation
Also Published As
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