CO5680454A2 - Composicion de vacuna que comprende proteina de enlace de transferrina y hsf de bacteria gram-negativa - Google Patents
Composicion de vacuna que comprende proteina de enlace de transferrina y hsf de bacteria gram-negativaInfo
- Publication number
- CO5680454A2 CO5680454A2 CO05007265A CO05007265A CO5680454A2 CO 5680454 A2 CO5680454 A2 CO 5680454A2 CO 05007265 A CO05007265 A CO 05007265A CO 05007265 A CO05007265 A CO 05007265A CO 5680454 A2 CO5680454 A2 CO 5680454A2
- Authority
- CO
- Colombia
- Prior art keywords
- hsf
- negativa
- transferrine
- vaccine composition
- protein
- Prior art date
Links
- 241000894006 Bacteria Species 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 108700041430 link Proteins 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 3
- 230000002163 immunogen Effects 0.000 abstract 3
- 101000812705 Gallus gallus Endoplasmin Proteins 0.000 abstract 2
- 101710123608 HSF-like protein Proteins 0.000 abstract 2
- 102000010912 Transferrin-Binding Proteins Human genes 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
- A61K39/1045—Moraxella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0218051A GB0218051D0 (en) | 2002-08-02 | 2002-08-02 | Vaccine composition |
| GB0218037A GB0218037D0 (en) | 2002-08-02 | 2002-08-02 | Vaccine composition |
| GB0218035A GB0218035D0 (en) | 2002-08-02 | 2002-08-02 | Vaccine composition |
| GB0218036A GB0218036D0 (en) | 2002-08-02 | 2002-08-02 | Vaccine |
| GBGB0220197.8A GB0220197D0 (en) | 2002-08-30 | 2002-08-30 | Refolding method |
| GBGB0220199.4A GB0220199D0 (en) | 2002-08-30 | 2002-08-30 | Mutant protein and refolding method |
| GB0225524A GB0225524D0 (en) | 2002-11-01 | 2002-11-01 | Vaccine composition |
| GB0225531A GB0225531D0 (en) | 2002-11-01 | 2002-11-01 | Vaccine |
| GB0230164A GB0230164D0 (en) | 2002-12-24 | 2002-12-24 | Vaccine composition |
| GB0230170A GB0230170D0 (en) | 2002-12-24 | 2002-12-24 | Vaccine |
| GB0230168A GB0230168D0 (en) | 2002-12-24 | 2002-12-24 | Vaccine composition |
| GB0305028A GB0305028D0 (en) | 2003-03-05 | 2003-03-05 | Vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5680454A2 true CO5680454A2 (es) | 2006-09-29 |
Family
ID=31722002
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO05007265A CO5680454A2 (es) | 2002-08-02 | 2005-01-28 | Composicion de vacuna que comprende proteina de enlace de transferrina y hsf de bacteria gram-negativa |
| CO05007268A CO5680456A2 (es) | 2002-08-02 | 2005-01-28 | Composiciones de vacunas que comprenden lipooligosacaridos del inmunotipo l2 y/o l3 a partir de lgtb-neisseria minigitidis |
| CO05007266A CO5680455A2 (es) | 2002-08-02 | 2005-01-28 | Composiciones de vacuna de neisserial que comprende una com binacion de antigenos |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO05007268A CO5680456A2 (es) | 2002-08-02 | 2005-01-28 | Composiciones de vacunas que comprenden lipooligosacaridos del inmunotipo l2 y/o l3 a partir de lgtb-neisseria minigitidis |
| CO05007266A CO5680455A2 (es) | 2002-08-02 | 2005-01-28 | Composiciones de vacuna de neisserial que comprende una com binacion de antigenos |
Country Status (25)
| Country | Link |
|---|---|
| US (9) | US20060057160A1 (enExample) |
| EP (11) | EP2255826B1 (enExample) |
| JP (7) | JP2006506467A (enExample) |
| KR (6) | KR101140033B1 (enExample) |
| CN (2) | CN1674933B (enExample) |
| AU (6) | AU2003253375B2 (enExample) |
| CA (4) | CA2493124C (enExample) |
| CO (3) | CO5680454A2 (enExample) |
| CY (3) | CY1114243T1 (enExample) |
| DE (2) | DE20321889U1 (enExample) |
| DK (2) | DK1524993T3 (enExample) |
| ES (3) | ES2575014T3 (enExample) |
| HU (1) | HUE029200T2 (enExample) |
| IL (3) | IL165660A0 (enExample) |
| IS (3) | IS7593A (enExample) |
| LU (1) | LU92262I2 (enExample) |
| MX (3) | MXPA05000842A (enExample) |
| MY (1) | MY149591A (enExample) |
| NO (3) | NO20050008L (enExample) |
| NZ (4) | NZ574530A (enExample) |
| PL (5) | PL375382A1 (enExample) |
| PT (2) | PT1524993E (enExample) |
| SI (2) | SI1524993T1 (enExample) |
| TW (1) | TWI360424B (enExample) |
| WO (4) | WO2004014419A1 (enExample) |
Families Citing this family (142)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2261347A3 (en) | 1998-05-01 | 2012-01-11 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
| US10967045B2 (en) * | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
| GB9823978D0 (en) * | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
| CA2372235A1 (en) | 1999-04-30 | 2000-11-09 | Rino Rappuoli | Conserved neisserial antigens |
| AU783894B2 (en) * | 1999-05-19 | 2005-12-22 | Novartis Vaccines And Diagnostics S.R.L. | Combination neisserial compositions |
| GB9918319D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| EP1226253A2 (en) | 1999-10-29 | 2002-07-31 | Chiron S.P.A. | Neisserial antigenic peptides |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| MXPA02007184A (es) * | 2000-01-25 | 2004-02-26 | Univ Queensland | Proteinas que comprenden regiones conservadas de antigenos de superficie nhha de neisseria meningitidis. |
| DK1947187T5 (da) * | 2000-02-28 | 2011-10-24 | Novartis Vaccines & Diagnostic | Hybrid ekspression af neisserial-proteiner |
| KR20030024811A (ko) | 2000-07-27 | 2003-03-26 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 나이세리아 메닌지티디스에 의하여 유발되는 질병에 대한광범위하게 유효한 보호를 위한 백신 |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| ATE469915T1 (de) | 2001-07-27 | 2010-06-15 | Novartis Vaccines & Diagnostic | Antikörper gegen das meningokokken adhäsin app |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| CA2493124C (en) * | 2002-08-02 | 2014-04-29 | Glaxosmithkline Biologicals S.A. | Vaccine |
| GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| CN1809380B (zh) * | 2002-10-11 | 2010-05-12 | 启龙有限公司 | 广泛防御高毒性脑膜炎球菌谱系的多肽-疫苗 |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| NZ542586A (en) | 2003-04-09 | 2009-11-27 | Biogenerix Ag | Method of forming a covalent conjugate between a G-CSF peptide and PEG |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| US9005625B2 (en) | 2003-07-25 | 2015-04-14 | Novo Nordisk A/S | Antibody toxin conjugates |
| ES2395022T3 (es) | 2003-09-19 | 2013-02-07 | Epitopix, Llc | Polipéptidos de Campylobacter y sus métodos de uso |
| NZ546430A (en) | 2003-10-02 | 2009-04-30 | Novartis Vaccines & Diagnostic | Liquid vaccines for multiple meningococcal serogroups |
| GB0323709D0 (en) * | 2003-10-09 | 2003-11-12 | Health Prot Agency | Modified whole cell,cell extract and omv-based vaccines |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| JP5173194B2 (ja) | 2003-12-23 | 2013-03-27 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| CN1997392B (zh) * | 2004-05-11 | 2011-06-01 | 荷兰健康、福利与体育部部长代表的荷兰国 | 作为佐剂的脑膜炎奈瑟氏菌lgtB LOS |
| WO2006010143A2 (en) | 2004-07-13 | 2006-01-26 | Neose Technologies, Inc. | Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1] |
| GB0419408D0 (en) * | 2004-09-01 | 2004-10-06 | Chiron Srl | 741 chimeric polypeptides |
| GB0419627D0 (en) * | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| EP3061461A1 (en) | 2004-10-29 | 2016-08-31 | ratiopharm GmbH | Remodeling and glycopegylation of fibroblast growth factor (fgf) |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| GB0428381D0 (en) * | 2004-12-24 | 2005-02-02 | Isis Innovation | Vaccine |
| US9029331B2 (en) | 2005-01-10 | 2015-05-12 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
| NZ556651A (en) | 2005-01-21 | 2010-05-28 | Epitopix Llc | Yersinia spp. polypeptides and methods of use |
| LT2682126T (lt) | 2005-01-27 | 2017-02-27 | Children`s Hospital & Research Center at Oakland | Gna1870 pagrindu gaminamos pūslelių pavidalo vakcinos, skirtos plataus spektro apsaugai nuo neisseria meningitidis sukeltų ligų |
| EP1871795A4 (en) | 2005-04-08 | 2010-03-31 | Biogenerix Ag | COMPOSITIONS AND METHOD FOR PRODUCING GLYCOSYLATION MUTANTS OF A PROTEASE-RESISTANT HUMAN GROWTH HORMONE |
| LT2351578T (lt) | 2005-06-27 | 2017-04-10 | Glaxosmithkline Biologicals S.A. | Vakcinų gavimo būdas |
| US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| US7955817B2 (en) | 2005-09-02 | 2011-06-07 | Glaxosmithkline Biologicals S.A. | Vaccine protection assay |
| ES2407683T3 (es) * | 2005-09-05 | 2013-06-13 | Glaxosmithkline Biologicals S.A. | Ensayo bactericida del suero para antisuero específico de N. Meningitidis |
| WO2007056191A2 (en) | 2005-11-03 | 2007-05-18 | Neose Technologies, Inc. | Nucleotide sugar purification using membranes |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| US20110008279A1 (en) * | 2005-12-06 | 2011-01-13 | Vega Masignani | Methods and Compositions Relating to Adhesins as Adjuvants |
| BRPI0620460B8 (pt) | 2005-12-22 | 2021-05-25 | Glaxosmithkline Biologicals Sa | uso de composição imunogênica para bebês, e, processo para produzir uma vacina |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| CU23549A1 (es) * | 2005-12-29 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Composiciones farmacéuticas que contienen la proteína nma0939 |
| MY148405A (en) | 2006-03-30 | 2013-04-30 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| DE602007003596D1 (de) | 2006-06-12 | 2010-01-14 | Glaxosmithkline Biolog Sa | Impfstoff |
| US20080242607A1 (en) | 2006-07-21 | 2008-10-02 | Neose Technologies, Inc. | Glycosylation of peptides via o-linked glycosylation sequences |
| EA015964B1 (ru) | 2006-09-07 | 2012-01-30 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина |
| US8969532B2 (en) | 2006-10-03 | 2015-03-03 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography |
| GB0700136D0 (en) | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Process for manufacturing vaccines |
| GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
| CN101796063B (zh) | 2007-04-03 | 2017-03-22 | 拉蒂奥法姆有限责任公司 | 使用糖聚乙二醇化g‑csf的治疗方法 |
| US9493499B2 (en) | 2007-06-12 | 2016-11-15 | Novo Nordisk A/S | Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography |
| BRPI0813644B8 (pt) | 2007-06-26 | 2021-05-25 | Glaxosmithkline Biologicals Sa | composição imunogênica, vacina, processo para fabricar a mesma, e, uso da composição imunogênica ou vacina |
| CA2694532A1 (en) * | 2007-08-02 | 2009-02-05 | Glaxosmithkline Biologicals S.A. | Method of lipooligosaccharide (los) typing of a neisseria strain comprising detection of los biosynthesis genes |
| EP2185576A4 (en) * | 2007-08-02 | 2011-01-12 | Childrens Hosp & Res Ct Oak | FHBP- AND LPXL1-BASED VESICIUM VACCINES FOR BROADBAND PROTECTION AGAINST NEISSERIA MENINGITIDIS-RELATED DISEASES |
| BR122016015627A2 (pt) | 2007-10-19 | 2018-10-30 | Novartis Ag | kit, composição antigênica liofilizada e método para preparação de uma composição imunogênica |
| EP2886551A3 (en) | 2008-02-21 | 2015-09-23 | Novartis AG | Meningococcal fhbp polypeptides |
| DK2257311T3 (da) | 2008-02-27 | 2014-06-30 | Novo Nordisk As | Konjugerede Faktor VIII-Molekyler |
| ES2546213T3 (es) | 2008-03-03 | 2015-09-21 | Novartis Ag | Compuestos y composiciones como moduladores de la actividad de TLR |
| RU2477145C2 (ru) * | 2008-05-30 | 2013-03-10 | ДЗЕ Ю.Эс.Эй., ЭС РЕПРЕЗЕНТЕД БАЙ ДЗЕ СЕКРЕТАРИ ОФ ДЗЕ АРМИ, ОН БЕХАФ ОФ УОЛТЕР РИД АРМИ | Мультивалентная вакцина из нативных везикул наружной мембраны менингококков, способы ее получения и применения |
| KR101042541B1 (ko) * | 2008-07-25 | 2011-06-17 | 한국생명공학연구원 | 외막소체를 생산하는 재조합 g(-) 박테리아 및 이를이용한 다가항원이 실린 외막소체의 제조방법 |
| US20110182981A1 (en) * | 2008-08-25 | 2011-07-28 | Peixuan Zhu | Gonococcal vaccines |
| GB0816447D0 (en) * | 2008-09-08 | 2008-10-15 | Glaxosmithkline Biolog Sa | Vaccine |
| GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
| WO2010070453A2 (en) | 2008-12-17 | 2010-06-24 | Novartis Ag | Meningococcal vaccines including hemoglobin receptor |
| CN101759781B (zh) * | 2008-12-25 | 2013-04-03 | 上海市第六人民医院 | 一种细菌表层黏附蛋白及其用途 |
| EP2382985B1 (en) | 2008-12-25 | 2015-05-06 | The Chemo-Sero-Therapeutic Research Institute | Recombinant avian-infectious coryza vaccine and method for producing same |
| EP2208787A1 (en) * | 2009-01-19 | 2010-07-21 | Université de Liège | A recombinant alpha-hemolysin polypeptide of Staphylococcus aureus, having a deletion in the stem domain and heterologous sequences inserted |
| AU2010227221B2 (en) * | 2009-03-24 | 2015-01-22 | Novartis Ag | Combinations including pneumococcal serotype 14 saccharide |
| US20120064103A1 (en) | 2009-03-24 | 2012-03-15 | Novartis Ag | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
| PL2411048T3 (pl) | 2009-03-24 | 2020-11-16 | Glaxosmithkline Biologicals Sa | Adjuwantowe meningokokowe białko wiążące czynnik h |
| CA2762033A1 (fr) * | 2009-05-14 | 2010-11-18 | Sanofi Pasteur | Vaccin meningocoque a base de lipooligosaccharide (los) et de proteine de neisseria meningitidis |
| EP2430151B1 (fr) | 2009-05-14 | 2014-06-18 | Sanofi Pasteur | Vaccin meningocoque a base de lipooligosaccharide (los) provenant de souches modifiees de neisseria meningitidis d'immunotype l6 |
| WO2010130896A2 (fr) | 2009-05-14 | 2010-11-18 | Sanofi Pasteur | Procédé pour adjuver le lipopolysaccharide (lps) des bactéries à gram-négatif |
| JP5536765B2 (ja) * | 2009-05-20 | 2014-07-02 | 国立大学法人鳥取大学 | 部分糖鎖エピトープを用いた、病原性ナイセリア属細菌感染の検出方法およびそれら細菌に対するワクチン |
| CA2765112A1 (en) | 2009-06-10 | 2010-12-16 | Novartis Ag | Benzonaphthyridine-containing vaccines |
| GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| JP2013502918A (ja) | 2009-08-27 | 2013-01-31 | ノバルティス アーゲー | 髄膜炎菌fHBP配列を含むハイブリッドポリペプチド |
| US8858958B2 (en) | 2009-08-27 | 2014-10-14 | Novartis Ag | Adjuvant comprising aluminum, oligonucleotide and polycation |
| WO2011027971A2 (ko) | 2009-09-01 | 2011-03-10 | 주식회사이언메딕스 | 장내 공생 세균유래 세포밖 소포체, 및 이를 이용한 질병모델, 백신, 후보 약물 탐색 방법, 및 진단 방법 |
| WO2011027956A2 (ko) | 2009-09-04 | 2011-03-10 | 주식회사이언메딕스 | 그람 양성 박테리아에서 유래한 세포밖 소포체 및 이를 이용한 질병 모델 |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| AU2010290896B2 (en) | 2009-09-02 | 2014-07-03 | Glaxosmithkline Biologicals S.A. | Immunogenic compositions including TLR activity modulators |
| GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
| GB0917002D0 (en) * | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Improved shigella blebs |
| US20130022639A1 (en) | 2009-09-30 | 2013-01-24 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
| BR112012010531A2 (pt) | 2009-10-27 | 2019-09-24 | Novartis Ag | "polipeptídeos de modificação meningocócica fhbp" |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| CA2779839A1 (en) * | 2009-11-06 | 2011-05-12 | Children's Hospital & Research Center At Oakland | T-cell stimulating protein b and methods of use |
| US9408907B2 (en) | 2009-12-15 | 2016-08-09 | Glaxosmithkline Biologicals Sa | Homogenous suspension of immunopotentiating compounds and uses thereof |
| EP2544714A1 (en) | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Vaccine composition |
| BR112012022800A2 (pt) * | 2010-03-11 | 2018-05-15 | Glaxosmithkline Biologicals Sa | composição imunogênica ou vacina, cepa bacteriana gram-negativa geneticamente engenheirada, métodos para o tratamento ou prevenção de infecção ou doença, para produzir uma composição imunogênica ou uma vacina, e para preparar uma imunoglobulina, preparação da imunoglobulina, e, preparação farmacêutica |
| WO2012020326A1 (en) | 2010-03-18 | 2012-02-16 | Novartis Ag | Adjuvanted vaccines for serogroup b meningococcus |
| AU2011232421B2 (en) | 2010-03-23 | 2015-08-13 | Novartis Ag | Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc. |
| AU2013202310C1 (en) * | 2010-03-29 | 2017-01-05 | Nationwide Children's Hospital, Inc. | Compositions and methods for the removal of biofilms |
| SG183816A1 (en) * | 2010-03-29 | 2012-10-30 | Res Inst Nationwide Childrens Hospital | Compositions and methods for the removal of biofilms |
| CA2803239A1 (en) | 2010-06-25 | 2011-12-29 | Novartis Ag | Combinations of meningococcal factor h binding proteins |
| EP2613797B1 (en) | 2010-09-09 | 2015-11-04 | University Of Southern California | Compositions and methods for the removal of biofilms |
| BR112013005626B1 (pt) | 2010-09-10 | 2022-07-26 | Glaxosmithkline Biologicals Sa | Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição |
| GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| CA2811699C (en) * | 2010-09-28 | 2019-07-02 | Abera Bioscience Ab | Fusion protein for secretory protein expression |
| WO2012054879A1 (en) * | 2010-10-22 | 2012-04-26 | Duke University | Compositions and methods for the treatment of septic arthritis, osteomyelitis, and bacteremia |
| US20150147356A1 (en) | 2011-05-12 | 2015-05-28 | Alan Kimura | Antipyretics to enhance tolerability of vesicle-based vaccines |
| PL2729167T3 (pl) * | 2011-07-07 | 2018-08-31 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws | Sposób wolnego od detergentów wytwarzania pęcherzyków zewnątrzbłonowych bakterii Gram-ujemnych |
| AU2011384634A1 (en) | 2011-12-29 | 2014-06-19 | Novartis Ag | Adjuvanted combinations of meningococcal factor H binding proteins |
| MX2014008988A (es) | 2012-02-02 | 2014-08-27 | Novartis Ag | Promotores para aumento de expresion de proteinas en meningococo. |
| JP5698693B2 (ja) * | 2012-03-13 | 2015-04-08 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 髄膜炎菌特異的抗血清に対する血清殺菌アッセイ |
| MX357538B (es) | 2012-06-14 | 2018-07-13 | Novartis Ag | Vacunas para meningococo de serogrupo x. |
| EP2892553A1 (en) | 2012-09-06 | 2015-07-15 | Novartis AG | Combination vaccines with serogroup b meningococcus and d/t/p |
| RU2662970C2 (ru) | 2012-09-18 | 2018-07-31 | Новартис Аг | Везикулы наружной мембраны |
| US20160120818A1 (en) | 2013-02-07 | 2016-05-05 | Glaxosmithline Biological Sa | Pharmaceutical compositions comprising vesicles |
| WO2014138290A1 (en) * | 2013-03-05 | 2014-09-12 | Trudeau Institute, Inc. | Compositions and methods for treating bacterial infections |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US9745366B2 (en) | 2013-09-23 | 2017-08-29 | University Of Southern California | Compositions and methods for the prevention of microbial infections |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US10233234B2 (en) | 2014-01-13 | 2019-03-19 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| CA2940447C (en) | 2014-02-28 | 2023-07-11 | Glaxosmithkline Biologicals Sa | Modified meningococcal fhbp polypeptides |
| EP3229835A1 (en) | 2014-12-09 | 2017-10-18 | Sanofi Pasteur | Compositions comprising n. meningitidis proteins |
| EP3298031B1 (en) | 2015-05-18 | 2020-10-21 | BiOMVis Srl | Immunogenic compositions containing bacterial outer membrane vesicles and therapeutic uses thereof |
| CA2993009A1 (en) | 2015-07-31 | 2017-02-09 | Research Institute At Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| WO2017066719A2 (en) | 2015-10-14 | 2017-04-20 | Research Institute At Nationwide Children's Hospital | Hu specific interfering agents |
| KR101825439B1 (ko) * | 2016-04-15 | 2018-02-05 | 배재대학교 산학협력단 | 염산 처리에 의한 그람양성 박테리아 고스트의 제조 방법 |
| CA3049114A1 (en) | 2017-01-04 | 2018-07-12 | Lauren O. Bakaletz | Antibody fragments for the treatment of biofilm-related disorders |
| JP7514621B2 (ja) | 2017-01-04 | 2024-07-11 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | Dnabiiワクチンおよび強化された活性を有する抗体 |
| AU2018236271B2 (en) | 2017-03-15 | 2023-12-21 | Research Institute At Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| WO2020072993A1 (en) | 2018-10-05 | 2020-04-09 | Research Institute At Nationwide Children's Hospital | Hmgb1 protein derivatives for the removal of biofilms cross-reference to related application |
| US12128094B2 (en) * | 2018-11-06 | 2024-10-29 | Glaxosmithkline Biologicals Sa | Immunogenic compositions comprising OMVs, an acellular pertussis antigen, a tetanus toxoid and a diphtheria toxoid |
| WO2020168146A1 (en) * | 2019-02-14 | 2020-08-20 | University Of Florida Research Foundation, Inc. | Honeybee commensal snodgrassella alvi vaccine against pathogenic neisseriaceae |
| FR3099160B1 (fr) * | 2019-07-23 | 2022-05-06 | Univ Grenoble Alpes | Anticorps dirigé contre la protéine oprf depseudomonas aeruginosa, son utilisation en tant que médicament et composition pharmaceutique le contenant |
| WO2021224439A1 (en) * | 2020-05-08 | 2021-11-11 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport | CLICK OMVs |
| WO2023097652A1 (en) * | 2021-12-03 | 2023-06-08 | National Center For Nanoscience And Technology | An engineered cell and application thereof |
| GB202203250D0 (en) | 2022-03-09 | 2022-04-20 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
| CN119792504A (zh) * | 2023-10-10 | 2025-04-11 | 康希诺生物股份公司 | 一种抗脑膜炎球菌的免疫组合物及其用途 |
| WO2026015688A1 (en) * | 2024-07-11 | 2026-01-15 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treating bacterial disease |
Family Cites Families (131)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4239746A (en) * | 1973-06-30 | 1980-12-16 | Dezso Istvan Bartos | Complement fixation test employing reactants in a disposable package |
| DE2744721A1 (de) | 1977-10-05 | 1979-04-19 | Veba Chemie Ag | Pulverfoermige ueberzugsmittel und deren anwendung |
| DE2848965A1 (de) | 1978-11-11 | 1980-05-22 | Behringwerke Ag | Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine |
| EP0027888B1 (en) | 1979-09-21 | 1986-04-16 | Hitachi, Ltd. | Semiconductor switch |
| US4271147A (en) | 1980-01-10 | 1981-06-02 | Behringwerke Aktiengesellschaft | Process for the isolation of membrane proteins from Neisseria meningitidis and vaccines containing same |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| US20020146764A1 (en) * | 1985-03-28 | 2002-10-10 | Chiron Corporation | Expression using fused genes providing for protein product |
| IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
| DE3622221A1 (de) * | 1986-07-02 | 1988-01-14 | Max Planck Gesellschaft | Verfahren zur gentechnologischen gewinnung von proteinen unter verwendung gramnegativer wirtszellen |
| US5173294A (en) | 1986-11-18 | 1992-12-22 | Research Foundation Of State University Of New York | Dna probe for the identification of haemophilus influenzae |
| JPH01125328A (ja) | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | 髄膜炎菌ワクチン |
| MC2178A1 (fr) | 1988-12-16 | 1992-05-22 | Nederlanden Staat | Mutants de la pneumolysine et vaccins a base de pneumocoque prepares a partir de ces mutants |
| US7118757B1 (en) * | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
| CU22302A1 (es) * | 1990-09-07 | 1995-01-31 | Cigb | Secuencia nucleotidica codificante para una proteina de la membrana externa de neisseria meningitidis y uso de dicha proteina en preparados vacunales |
| DE69133276T2 (de) | 1990-07-16 | 2003-11-27 | University Of North Carolina At Chapel Hill, Chapel Hill | Mit der familie der hämolysin-toxine verwandte antigene eisen-ubnterdrückende proteine des n. meningitis |
| DE4023721A1 (de) | 1990-07-26 | 1992-01-30 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von vakzinen und ihre verwendung |
| JP3532563B2 (ja) | 1990-08-23 | 2004-05-31 | ザ ユニバーシティー オブ ノースカロライナ アット チャペル ヒル | Neisseria gonorrhoeaeおよびNeisseria meningitidis由来トランスフェリン結合蛋白質 |
| US5912336A (en) | 1990-08-23 | 1999-06-15 | University Of North Carolina At Chapel Hill | Isolated nucleic acid molecules encoding transferrin binding proteins from Neisseria gonorrhoeae and Neisseria meningitidis |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| US5371186A (en) | 1991-02-11 | 1994-12-06 | Biosynth S.R.L. | Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock |
| US5652211A (en) | 1991-02-11 | 1997-07-29 | Biosynth S.R.L. | Peptides for neutralizing the toxicity of Lipid A |
| US5476929A (en) | 1991-02-15 | 1995-12-19 | Uab Research Foundation | Structural gene of pneumococcal protein |
| US6592876B1 (en) | 1993-04-20 | 2003-07-15 | Uab Research Foundation | Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products |
| CA2105382C (en) * | 1991-03-14 | 1999-01-19 | Neil Goldstein | Recombinant hybrid porin epitopes |
| US5552146A (en) | 1991-08-15 | 1996-09-03 | Board Of Regents, The University Of Texas System | Methods and compositions relating to useful antigens of Moraxella catarrhalis |
| FR2682041B1 (fr) | 1991-10-03 | 1994-01-14 | Pasteur Merieux Serums Vaccins | Vaccin contre les infections a neisseria meningitidis. |
| EP0621886A1 (en) | 1992-01-13 | 1994-11-02 | Akzo Nobel N.V. | Crosslinking of rubbers with engineering plastics |
| AU685047B2 (en) | 1992-02-11 | 1998-01-15 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Dual carrier immunogenic construct |
| FR2692592B1 (fr) | 1992-06-19 | 1995-03-31 | Pasteur Merieux Serums Vacc | Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant. |
| CA2138997C (en) | 1992-06-25 | 2003-06-03 | Jean-Paul Prieels | Vaccine composition containing adjuvants |
| NL9201716A (nl) * | 1992-10-02 | 1994-05-02 | Nederlanden Staat | Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat. |
| GB9224584D0 (en) | 1992-11-23 | 1993-01-13 | Connaught Lab | Use of outer membrane protein d15 and its peptides as vaccine against haempohilus influenzae diseases |
| ES2185658T3 (es) | 1993-05-18 | 2003-05-01 | Univ Ohio State Res Found | Vacuna para la otitis media. |
| US5439808A (en) * | 1993-07-23 | 1995-08-08 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
| US6361779B1 (en) | 1993-11-08 | 2002-03-26 | Aventis Pasteur Limited | Transferrin receptor genes |
| CN1267553C (zh) | 1993-11-08 | 2006-08-02 | 康诺特实验室有限公司 | 嗜血杆菌属转铁蛋白受体基因 |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| WO1996002555A1 (en) | 1994-07-15 | 1996-02-01 | The University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
| US5565204A (en) | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
| US5545553A (en) | 1994-09-26 | 1996-08-13 | The Rockefeller University | Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them |
| US6287574B1 (en) * | 1995-03-17 | 2001-09-11 | Biochem Pharma Inc. | Proteinase K resistant surface protein of neisseria meningitidis |
| IL117483A (en) | 1995-03-17 | 2008-03-20 | Bernard Brodeur | MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K. |
| US6265567B1 (en) | 1995-04-07 | 2001-07-24 | University Of North Carolina At Chapel Hill | Isolated FrpB nucleic acid molecule |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US6440425B1 (en) | 1995-05-01 | 2002-08-27 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
| US5843464A (en) | 1995-06-02 | 1998-12-01 | The Ohio State University | Synthetic chimeric fimbrin peptides |
| US6007838A (en) | 1995-06-07 | 1999-12-28 | The United States Of America As Represented By The Secretary Of The Army | Process for making liposome preparation |
| AU700080B2 (en) | 1995-06-07 | 1998-12-17 | Biochem Vaccines Inc. | Streptococcal heat shock proteins members of the HSP70 family |
| GB9513074D0 (en) | 1995-06-27 | 1995-08-30 | Cortecs Ltd | Novel anigen |
| EP0854729B2 (en) * | 1995-09-18 | 2008-10-22 | United States Army Medical Research Materiel Command (USAMRMC) | Improved methods for the production of non-covalently complexed and multivalent proteosome sub-unit vaccines |
| US6290970B1 (en) | 1995-10-11 | 2001-09-18 | Aventis Pasteur Limited | Transferrin receptor protein of Moraxella |
| US6440701B1 (en) | 1996-03-08 | 2002-08-27 | Aventis Pasteur Limited | Transferrin receptor genes of Moraxella |
| US6090576A (en) | 1996-03-08 | 2000-07-18 | Connaught Laboratories Limited | DNA encoding a transferrin receptor of Moraxella |
| EP0912608B1 (en) | 1996-05-01 | 2006-04-19 | The Rockefeller University | Choline binding proteins for anti-pneumococcal vaccines |
| US7341727B1 (en) | 1996-05-03 | 2008-03-11 | Emergent Product Development Gaithersburg Inc. | M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same |
| FR2751000B1 (fr) | 1996-07-12 | 1998-10-30 | Inst Nat Sante Rech Med | Adn specifiques des bacteries de l'espece neisseria meningitidis, leurs procedes d'obtention et leurs applications biologiques |
| US5882896A (en) | 1996-09-24 | 1999-03-16 | Smithkline Beecham Corporation | M protein |
| US5882871A (en) | 1996-09-24 | 1999-03-16 | Smithkline Beecham Corporation | Saliva binding protein |
| CA2271720A1 (en) | 1996-10-31 | 1998-05-07 | Human Genome Sciences, Inc. | Streptococcus pneumoniae polynucleotides and sequences |
| JP2001502925A (ja) | 1997-06-03 | 2001-03-06 | コノート ラボラトリーズ リミテッド | モラクセラのラクトフェリン受容体遺伝子 |
| AU740956B2 (en) | 1997-07-21 | 2001-11-15 | Baxter Healthcare Sa | Modified immunogenic pneumolysin compositions as vaccines |
| WO1999006781A1 (de) | 1997-07-31 | 1999-02-11 | Wilo Gmbh | Latentwärmespeicher für ein kraftfahrzeug |
| BR9811907A (pt) | 1997-08-15 | 2000-08-15 | Univ Utrecht | Proteìna de ligação de lactoferrina de neisseria |
| GB9717953D0 (en) | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
| US6914131B1 (en) * | 1998-10-09 | 2005-07-05 | Chiron S.R.L. | Neisserial antigens |
| GB9726398D0 (en) | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
| WO1999036544A2 (en) * | 1998-01-14 | 1999-07-22 | Chiron S.P.A. | Neisseria meningitidis antigens |
| CA2264970A1 (en) * | 1998-03-10 | 1999-09-10 | American Cyanamid Company | Antigenic conjugates of conserved lipolysaccharides of gram negative bacteria |
| EP1067962B1 (en) | 1998-04-07 | 2010-03-24 | MedImmune, LLC | Derivatives of pneumococcal choline binding proteins for vaccines |
| GB9808734D0 (en) | 1998-04-23 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
| GB9808866D0 (en) | 1998-04-24 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
| EP2261347A3 (en) * | 1998-05-01 | 2012-01-11 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
| US20070026021A1 (en) * | 1998-05-01 | 2007-02-01 | Chiron S.R.I. | Neisseria meningitidis antigens and compositions |
| GB9809683D0 (en) | 1998-05-06 | 1998-07-01 | Smithkline Beecham Biolog | Novel compounds |
| GB9810276D0 (en) | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
| GB9810285D0 (en) | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
| GB9811260D0 (en) | 1998-05-26 | 1998-07-22 | Smithkline Beecham Biolog | Novel compounds |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| KR20070089890A (ko) | 1998-06-03 | 2007-09-03 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 모락셀라 카탈리스로부터의 basb027 단백질 및 유전자,항원, 항체, 및 이들의 용도 |
| GB9812163D0 (en) | 1998-06-05 | 1998-08-05 | Smithkline Beecham Biolog | Novel compounds |
| GB9812440D0 (en) | 1998-06-09 | 1998-08-05 | Smithkline Beecham Biolog | Novel compounds |
| GB9814902D0 (en) | 1998-07-10 | 1998-09-09 | Univ Nottingham | Screening of neisserial vaccine candidates against pathogenic neisseria |
| US6951652B2 (en) | 1998-07-29 | 2005-10-04 | Biosynth S.R.L. | Vaccine for prevention of gram-negative bacterial infections and endotoxin related diseases |
| GB9818004D0 (en) * | 1998-08-18 | 1998-10-14 | Smithkline Beecham Biolog | Novel compounds |
| GB9820003D0 (en) | 1998-09-14 | 1998-11-04 | Smithkline Beecham Biolog | Novel compounds |
| GB9820002D0 (en) | 1998-09-14 | 1998-11-04 | Smithkline Beecham Biolog | Novel compounds |
| MXPA01003557A (es) * | 1998-10-09 | 2004-04-05 | Chiron Corp | Secuencias genomicas de neisseria y metodos para su uso. |
| BR9915543A (pt) | 1998-10-16 | 2001-08-14 | Fraunhofer Ges Forschung | Resistência a doenças por plantas mediada por patogenicidas moleculares |
| CA2347849C (en) * | 1998-10-22 | 2013-06-25 | The University Of Montana | Omp85 proteins of neisseria gonorrhoeae and neisseria meningitidis, compositions containing same and methods of use thereof |
| US6610306B2 (en) * | 1998-10-22 | 2003-08-26 | The University Of Montana | OMP85 protein of neisseria meningitidis, compositions containing the same and methods of use thereof |
| GB9823978D0 (en) * | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
| US20030215469A1 (en) * | 1998-11-02 | 2003-11-20 | Microbiological Research Authority | Multicomponent meningococcal vaccine |
| PT1127137E (pt) | 1998-11-03 | 2007-12-28 | Staat Nl Verteg Door Min Welzi | Lps com toxicidade reduzida a partir de bactérias gramnegativas modificadas geneticamente |
| CA2371032A1 (en) * | 1999-04-30 | 2000-11-09 | Chiron Corporation | Neisseria genomic sequences and methods of their use |
| CA2372235A1 (en) * | 1999-04-30 | 2000-11-09 | Rino Rappuoli | Conserved neisserial antigens |
| AU783894B2 (en) * | 1999-05-19 | 2005-12-22 | Novartis Vaccines And Diagnostics S.R.L. | Combination neisserial compositions |
| GB9911683D0 (en) * | 1999-05-19 | 1999-07-21 | Chiron Spa | Antigenic peptides |
| WO2000078968A2 (en) | 1999-06-18 | 2000-12-28 | Elitra Pharmaceuticals, Inc. | Nucleotide sequences of moraxella catarrhalis genome |
| GB2351515B (en) | 1999-06-29 | 2002-09-11 | Pandrol Ltd | Adjustable railway rail fastening assembly and methods for use therewith |
| GB9917977D0 (en) | 1999-07-30 | 1999-09-29 | Smithkline Beecham Biolog | Novel compounds |
| GB9918038D0 (en) | 1999-07-30 | 1999-09-29 | Smithkline Beecham Biolog | Novel compounds |
| GB9918208D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Novel compounds |
| GB9918319D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| GB9918302D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Novel compounds |
| US6531131B1 (en) * | 1999-08-10 | 2003-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for Neisseria meningitidis |
| AUPQ275799A0 (en) * | 1999-09-10 | 1999-10-07 | Luminis Pty Limited | Recombinant bacterium expressing an oligosaccharide receptor mimic |
| EP1234039A2 (en) | 1999-11-29 | 2002-08-28 | Chiron Spa | 85kDa NEISSERIAL ANTIGEN |
| CA2871789C (en) * | 2000-01-17 | 2017-04-04 | Novartis Vaccines And Diagnostics S.R.L. | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins |
| MXPA02007184A (es) | 2000-01-25 | 2004-02-26 | Univ Queensland | Proteinas que comprenden regiones conservadas de antigenos de superficie nhha de neisseria meningitidis. |
| DK1947187T5 (da) * | 2000-02-28 | 2011-10-24 | Novartis Vaccines & Diagnostic | Hybrid ekspression af neisserial-proteiner |
| GB0007432D0 (en) * | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| GB0011108D0 (en) * | 2000-05-08 | 2000-06-28 | Microscience Ltd | Virulence gene and protein and their use |
| KR20030024811A (ko) | 2000-07-27 | 2003-03-26 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 나이세리아 메닌지티디스에 의하여 유발되는 질병에 대한광범위하게 유효한 보호를 위한 백신 |
| GB0103424D0 (en) * | 2001-02-12 | 2001-03-28 | Chiron Spa | Gonococcus proteins |
| GB0108024D0 (en) * | 2001-03-30 | 2001-05-23 | Chiron Spa | Bacterial toxins |
| GB0115176D0 (en) * | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| EP1409013B1 (en) * | 2001-07-26 | 2009-11-18 | Novartis Vaccines and Diagnostics S.r.l. | Vaccines comprising aluminium adjuvants and histidine |
| GB0118249D0 (en) * | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) * | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| ATE469915T1 (de) * | 2001-07-27 | 2010-06-15 | Novartis Vaccines & Diagnostic | Antikörper gegen das meningokokken adhäsin app |
| WO2003028661A2 (en) * | 2001-10-03 | 2003-04-10 | Chiron Corporation | Adjuvanted meningococcus compositions |
| CA2493124C (en) * | 2002-08-02 | 2014-04-29 | Glaxosmithkline Biologicals S.A. | Vaccine |
| CN1809380B (zh) * | 2002-10-11 | 2010-05-12 | 启龙有限公司 | 广泛防御高毒性脑膜炎球菌谱系的多肽-疫苗 |
| ES2461350T3 (es) * | 2003-01-30 | 2014-05-19 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
| GB0315021D0 (en) * | 2003-06-26 | 2003-07-30 | Chiron Srl | Immunogenic gonococcal compositions |
| NZ546430A (en) * | 2003-10-02 | 2009-04-30 | Novartis Vaccines & Diagnostic | Liquid vaccines for multiple meningococcal serogroups |
| GB0323103D0 (en) * | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| GB0408977D0 (en) * | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| GB0409748D0 (en) * | 2004-04-30 | 2004-06-09 | Chiron Srl | Lactoferrin cleavage |
| CN101479293A (zh) * | 2006-06-29 | 2009-07-08 | 诺华有限公司 | 脑膜炎奈瑟球菌多肽 |
-
2003
- 2003-07-31 CA CA2493124A patent/CA2493124C/en not_active Expired - Fee Related
- 2003-07-31 PL PL03375382A patent/PL375382A1/xx not_active IP Right Cessation
- 2003-07-31 MX MXPA05000842A patent/MXPA05000842A/es active IP Right Grant
- 2003-07-31 CN CN038186489A patent/CN1674933B/zh not_active Expired - Fee Related
- 2003-07-31 WO PCT/EP2003/008567 patent/WO2004014419A1/en not_active Ceased
- 2003-07-31 NZ NZ574530A patent/NZ574530A/en not_active IP Right Cessation
- 2003-07-31 JP JP2005506114A patent/JP2006506467A/ja active Pending
- 2003-07-31 HU HUE10177890A patent/HUE029200T2/en unknown
- 2003-07-31 NZ NZ587398A patent/NZ587398A/en not_active IP Right Cessation
- 2003-07-31 CN CNA038184540A patent/CN1671413A/zh active Pending
- 2003-07-31 ES ES10177890.0T patent/ES2575014T3/es not_active Expired - Lifetime
- 2003-07-31 JP JP2005506112A patent/JP4740738B2/ja not_active Expired - Fee Related
- 2003-07-31 WO PCT/EP2003/008569 patent/WO2004015099A2/en not_active Ceased
- 2003-07-31 KR KR1020057001941A patent/KR101140033B1/ko not_active Expired - Fee Related
- 2003-07-31 NZ NZ537181A patent/NZ537181A/en not_active IP Right Cessation
- 2003-07-31 KR KR1020057001924A patent/KR20050028051A/ko not_active Withdrawn
- 2003-07-31 EP EP10177890.0A patent/EP2255826B1/en not_active Expired - Lifetime
- 2003-07-31 AU AU2003253375A patent/AU2003253375B2/en not_active Ceased
- 2003-07-31 CA CA002493977A patent/CA2493977A1/en not_active Abandoned
- 2003-07-31 EP EP10177881A patent/EP2258384A3/en not_active Withdrawn
- 2003-07-31 DK DK03784153.3T patent/DK1524993T3/da active
- 2003-07-31 EP EP08153843A patent/EP1961427A3/en not_active Withdrawn
- 2003-07-31 PL PL375407A patent/PL216662B1/pl unknown
- 2003-07-31 CA CA002489030A patent/CA2489030A1/en not_active Abandoned
- 2003-07-31 DK DK10177890.0T patent/DK2255826T3/en active
- 2003-07-31 SI SI200332262T patent/SI1524993T1/sl unknown
- 2003-07-31 US US10/523,055 patent/US20060057160A1/en not_active Abandoned
- 2003-07-31 PL PL03375408A patent/PL375408A1/xx not_active Application Discontinuation
- 2003-07-31 KR KR1020127002482A patent/KR101239242B1/ko not_active Expired - Fee Related
- 2003-07-31 EP EP03784153A patent/EP1524993B1/en not_active Revoked
- 2003-07-31 PL PL399214A patent/PL220107B1/pl unknown
- 2003-07-31 DE DE20321889U patent/DE20321889U1/de not_active Expired - Lifetime
- 2003-07-31 EP EP03784151A patent/EP1524991A1/en not_active Withdrawn
- 2003-07-31 SI SI200332485A patent/SI2255826T1/sl unknown
- 2003-07-31 AU AU2003269864A patent/AU2003269864A1/en not_active Abandoned
- 2003-07-31 KR KR1020117004904A patent/KR101237329B1/ko not_active Expired - Fee Related
- 2003-07-31 MX MXPA05001265A patent/MXPA05001265A/es active IP Right Grant
- 2003-07-31 US US10/523,044 patent/US7838014B2/en not_active Expired - Fee Related
- 2003-07-31 PT PT37841533T patent/PT1524993E/pt unknown
- 2003-07-31 EP EP12157807.4A patent/EP2481419A3/en not_active Withdrawn
- 2003-07-31 JP JP2005506111A patent/JP5409986B2/ja not_active Expired - Fee Related
- 2003-07-31 EP EP10177891A patent/EP2258386A3/en not_active Withdrawn
- 2003-07-31 US US10/523,117 patent/US20060240045A1/en not_active Abandoned
- 2003-07-31 EP EP10177892A patent/EP2258387A3/en not_active Withdrawn
- 2003-07-31 ES ES03784153T patent/ES2408251T3/es not_active Expired - Lifetime
- 2003-07-31 NZ NZ537904A patent/NZ537904A/en not_active IP Right Cessation
- 2003-07-31 JP JP2005506113A patent/JP2006500963A/ja active Pending
- 2003-07-31 DE DE20321890U patent/DE20321890U1/de not_active Expired - Lifetime
- 2003-07-31 ES ES03784152.5T patent/ES2537737T3/es not_active Expired - Lifetime
- 2003-07-31 AU AU2003260357A patent/AU2003260357B2/en not_active Ceased
- 2003-07-31 PT PT101778900T patent/PT2255826E/pt unknown
- 2003-07-31 MY MYPI20032904A patent/MY149591A/en unknown
- 2003-07-31 EP EP03784152.5A patent/EP1524992B1/en not_active Expired - Lifetime
- 2003-07-31 KR KR1020057001933A patent/KR20050039839A/ko not_active Ceased
- 2003-07-31 EP EP03750408A patent/EP1524990A2/en not_active Withdrawn
- 2003-07-31 PL PL399492A patent/PL399492A1/pl not_active Application Discontinuation
- 2003-07-31 EP EP10177887A patent/EP2258385A3/en not_active Withdrawn
- 2003-07-31 KR KR1020087019883A patent/KR101139976B1/ko not_active Expired - Fee Related
- 2003-07-31 WO PCT/EP2003/008571 patent/WO2004014418A2/en not_active Ceased
- 2003-07-31 CA CA002493092A patent/CA2493092A1/en not_active Abandoned
- 2003-07-31 TW TW092121011A patent/TWI360424B/zh not_active IP Right Cessation
- 2003-07-31 MX MXPA05001349A patent/MXPA05001349A/es active IP Right Grant
- 2003-07-31 US US10/523,114 patent/US20060034854A1/en not_active Abandoned
- 2003-07-31 AU AU2003250204A patent/AU2003250204B8/en not_active Ceased
- 2003-07-31 WO PCT/EP2003/008568 patent/WO2004014417A2/en not_active Ceased
-
2004
- 2004-12-09 IL IL16566004A patent/IL165660A0/xx unknown
- 2004-12-13 IS IS7593A patent/IS7593A/is unknown
- 2004-12-16 IS IS7601A patent/IS7601A/is unknown
-
2005
- 2005-01-03 NO NO20050008A patent/NO20050008L/no not_active Application Discontinuation
- 2005-01-03 NO NO20050010A patent/NO20050010L/no not_active Application Discontinuation
- 2005-01-20 IS IS7658A patent/IS7658A/is unknown
- 2005-01-20 IL IL166433A patent/IL166433A/en active IP Right Grant
- 2005-01-25 NO NO20050421A patent/NO20050421L/no not_active Application Discontinuation
- 2005-01-28 CO CO05007265A patent/CO5680454A2/es active IP Right Grant
- 2005-01-28 CO CO05007268A patent/CO5680456A2/es not_active Application Discontinuation
- 2005-01-28 CO CO05007266A patent/CO5680455A2/es not_active Application Discontinuation
-
2008
- 2008-06-04 AU AU2008202479A patent/AU2008202479C1/en not_active Ceased
- 2008-12-12 AU AU2008255270A patent/AU2008255270A1/en not_active Abandoned
-
2010
- 2010-10-21 US US12/909,621 patent/US8221770B2/en not_active Expired - Fee Related
- 2010-10-22 JP JP2010237357A patent/JP5414651B2/ja not_active Expired - Fee Related
-
2011
- 2011-03-04 JP JP2011047056A patent/JP2011142916A/ja active Pending
- 2011-05-31 IL IL213264A patent/IL213264A0/en unknown
- 2011-09-29 US US13/248,693 patent/US20120027800A1/en not_active Abandoned
- 2011-11-17 US US13/299,007 patent/US20120064119A1/en not_active Abandoned
- 2011-11-17 US US13/299,041 patent/US20120064120A1/en not_active Abandoned
-
2012
- 2012-02-10 JP JP2012026928A patent/JP5789203B2/ja not_active Expired - Fee Related
-
2013
- 2013-05-31 CY CY20131100435T patent/CY1114243T1/el unknown
- 2013-07-31 LU LU92262C patent/LU92262I2/fr unknown
- 2013-09-05 CY CY2013036C patent/CY2013036I1/el unknown
-
2015
- 2015-09-03 US US14/844,989 patent/US20160082097A1/en not_active Abandoned
-
2016
- 2016-06-15 CY CY20161100532T patent/CY1117643T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2001295673A1 (en) | Vaccine composition | |
| EP0757717A4 (en) | PAPILLOMAVIRUS VACCINE | |
| ATE229978T1 (de) | Helicobacter proteine und impstoffe | |
| ES2127184T3 (es) | Un metodo para aislar y purificar a partir de bacterias proteinas receptoras de transferrina y lactoferrina, y la preparacion de vacunas que las contienen. | |
| BG101995A (en) | Saponin and sterol-containing vaccines | |
| IL150602A (en) | Proteosome influenza vaccine, method for preparing such and use thereof | |
| DE69111440D1 (de) | Methoden und zusammensetzungen zur impfung gegen hiv. | |
| DK1539231T3 (da) | Iscom-præparation og anvendelse deraf | |
| IL165605A0 (en) | Molecular antigen arrays | |
| ATE315405T1 (de) | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung | |
| FR21C1005I2 (fr) | Antigenes de streptococcus pyogenes et fragments d'adn correspondants | |
| ATE551069T1 (de) | Mucin-fusionspolypeptid-vakzine, zusammensetzungen und ihre verwendung | |
| MXPA03001235A (es) | Purificacion de antigenos vhb para uso en vacunas. | |
| DK0939648T3 (da) | Rotavirusvaccineformuleringer | |
| ATE222930T1 (de) | Antigene arznei zur behandlung oder vorbeugung | |
| AU2002309259A1 (en) | Improved polysaccharide and glycoconjugate vaccines_____________ | |
| DE60038099D1 (de) | Neisseria impfstoffzusammensetzungen und methoden | |
| DE60136360D1 (de) | Antigen aus streptococcus pyogenes | |
| ATE372129T1 (de) | Impfstoff von umhüllten viren und verfahren zu seiner herstellung | |
| DE69835424D1 (de) | Boviner atmungs- und darmcoronavirus als impfstoff | |
| MXPA03007992A (es) | Composicion farmaceutica de fragmentos f(ab)2 de anticuerpos y un proceso para su preparacion | |
| ATE338819T1 (de) | Antigenes protein aus malassezia | |
| DK0792347T3 (da) | Fremgangsmåder til fremstilling af forbedrede antigene Heliobacter sp. og vacciner omfattende samme | |
| DK1219299T4 (da) | Allergivacciner og fremstilling deraf | |
| ATE353226T1 (de) | Adjuvanszusammensetzung enthaltend fha oder ein fha-fragment in freier form |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Application granted |