CO4750664A1 - Marcfortinas y parahercuamidas antiparasitarias - Google Patents

Marcfortinas y parahercuamidas antiparasitarias

Info

Publication number
CO4750664A1
CO4750664A1 CO96038153A CO96038153A CO4750664A1 CO 4750664 A1 CO4750664 A1 CO 4750664A1 CO 96038153 A CO96038153 A CO 96038153A CO 96038153 A CO96038153 A CO 96038153A CO 4750664 A1 CO4750664 A1 CO 4750664A1
Authority
CO
Colombia
Prior art keywords
paramercamamids
marcfortins
antiparasitic
oxides
alkyl
Prior art date
Application number
CO96038153A
Other languages
English (en)
Inventor
Michael F Clothier
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO4750664(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CO4750664A1 publication Critical patent/CO4750664A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Abstract

Compuestos 15-alquil-14-hidroxilo de la fórmula (III):en donde n1 es 1 a 3, sus N-óxidos y sus sales farmacéuticamente aceptables.
CO96038153A 1995-07-21 1996-07-19 Marcfortinas y parahercuamidas antiparasitarias CO4750664A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21

Publications (1)

Publication Number Publication Date
CO4750664A1 true CO4750664A1 (es) 1999-03-31

Family

ID=21695455

Family Applications (1)

Application Number Title Priority Date Filing Date
CO96038153A CO4750664A1 (es) 1995-07-21 1996-07-19 Marcfortinas y parahercuamidas antiparasitarias

Country Status (31)

Country Link
US (2) US5703078A (es)
EP (3) EP0871631B1 (es)
JP (2) JP4122447B2 (es)
KR (1) KR100428335B1 (es)
CN (2) CN1125824C (es)
AR (10) AR003466A1 (es)
AT (1) ATE311390T1 (es)
AU (1) AU699644B2 (es)
BR (7) BR9612974B8 (es)
CA (1) CA2225813C (es)
CO (1) CO4750664A1 (es)
CZ (1) CZ296008B6 (es)
DE (1) DE69635524T2 (es)
DK (2) DK0871631T3 (es)
ES (2) ES2439569T3 (es)
FI (2) FI115912B (es)
HK (2) HK1017883A1 (es)
HU (1) HU226296B1 (es)
ID (1) ID30373A (es)
MX (1) MX9800625A (es)
MY (1) MY113806A (es)
NO (1) NO324287B1 (es)
NZ (1) NZ311952A (es)
PL (1) PL185007B1 (es)
PT (1) PT1489082E (es)
RU (1) RU2162090C2 (es)
SI (1) SI0871631T1 (es)
SK (2) SK284833B6 (es)
TW (1) TW334436B (es)
WO (1) WO1997003988A1 (es)
ZA (1) ZA965908B (es)

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PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
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AR074482A1 (es) 2008-12-04 2011-01-19 Merial Ltd Derivados dimericos de avermectina y milbemicina
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
NZ600252A (en) 2009-12-04 2014-03-28 Merial Ltd Pesticidal bis-organosulfur compounds
WO2011075592A1 (en) 2009-12-17 2011-06-23 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
PL2513104T3 (pl) 2009-12-17 2016-08-31 Merial Inc Przeciwpasożytnicze związki dihydroazolu i zawierające je kompozycje
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
NZ610547A (en) 2010-11-16 2015-07-31 Merial Ltd Novel monensin derivatives for the treatment and prevention of protozoal infections
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
BR112013033568B1 (pt) 2011-06-27 2020-11-24 Merial, Inc Compostos eter amidopiridil e composiqoes, e seu uso contra parasitas
DK3172964T3 (da) 2011-09-12 2020-11-30 Boehringer Ingelheim Animal Health Usa Inc Parasitiske sammensætninger indeholdende et isoxazolinaktivstof, fremgangsmåde og anvendelser deraf
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
AU2012340351B2 (en) 2011-11-17 2017-06-15 Boehringer Ingelheim Animal Health USA Inc. Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof
BR122020002199B1 (pt) 2011-12-02 2021-01-19 Merial, Inc. formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
MD20170009A2 (ro) 2012-02-06 2017-07-31 Merial Limited Compoziţii veterinare antiparazitare orale cu conţinut de agenţi activi cu acţiune sistemică, metode şi aplicări ale acestora
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
SG10201704665QA (en) 2012-04-20 2017-07-28 Merial Inc Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
SG11201503959VA (en) 2012-11-20 2015-06-29 Merial Inc Anthelmintic compounds and compositions and method of using thereof
EP3063144B1 (en) 2013-11-01 2021-09-08 Boehringer Ingelheim Animal Health USA Inc. Antiparasitic and pesticidal isoxazoline compounds
US10857121B2 (en) 2014-04-17 2020-12-08 Merial Inc. Use of malononitrile compounds for protecting animals from parasites
JP6616786B2 (ja) 2014-05-19 2019-12-04 メリアル インコーポレイテッド 駆虫性化合物
NZ728102A (en) 2014-06-19 2018-04-27 Merial Inc Parasiticidal compositions comprising indole derivatives, methods and uses thereof
AU2015339096B2 (en) 2014-10-31 2018-08-02 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal composition comprising fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
SG10202103403SA (en) 2015-05-20 2021-05-28 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic depsipeptide compounds
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
JP2019535655A (ja) 2016-10-14 2019-12-12 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 殺虫性及び殺寄生虫性ビニルイソオキサゾリン化合物
CA3044038A1 (en) 2016-11-16 2018-05-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
HUE061497T2 (hu) 2017-08-14 2023-07-28 Boehringer Ingelheim Animal Health Usa Inc Peszticid és paraziticid hatású pirazol-izoxazolin vegyületek
WO2019157241A1 (en) 2018-02-08 2019-08-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
CN112996788A (zh) 2018-07-09 2021-06-18 勃林格殷格翰动物保健美国公司 驱蠕虫的杂环化合物
WO2020112374A1 (en) 2018-11-20 2020-06-04 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
EP3930684A1 (en) 2019-03-01 2022-01-05 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
JP2022526901A (ja) 2019-03-19 2022-05-27 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性アザベンゾチオフェンおよびアザベンゾフラン化合物
PE20231205A1 (es) 2020-05-29 2023-08-17 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos
CN111748503B (zh) * 2020-08-04 2021-12-14 华中农业大学 一种深海独岛枝芽胞杆菌培养基和剂型
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
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US4978656A (en) * 1988-08-12 1990-12-18 Merck & Co., Inc. Synthetic derivatives of paraherquamide
US4866060A (en) * 1988-08-19 1989-09-12 Merck & Co., Inc. Use of the natural product marcfortines as antiparasitic agents
US4923867A (en) * 1988-08-24 1990-05-08 Merck & Co., Inc. Synthetic marcfortine derivatives useful as antiparasitic agents
NZ233043A (en) * 1989-03-30 1992-09-25 Merck & Co Inc Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide
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GB9014194D0 (en) * 1990-06-26 1990-08-15 Pfizer Ltd Antiparasitic agents
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Also Published As

Publication number Publication date
JPH11509550A (ja) 1999-08-24
RU2162090C2 (ru) 2001-01-20
AR003466A1 (es) 1998-08-05
BR9612972B8 (pt) 2014-10-29
CZ296008B6 (cs) 2005-12-14
ATE311390T1 (de) 2005-12-15
SK5498A3 (en) 1998-08-05
JP2008007516A (ja) 2008-01-17
NO980255D0 (no) 1998-01-20
AR038434A2 (es) 2005-01-12
BR9612973B8 (pt) 2014-10-29
AR038431A2 (es) 2005-01-12
CN1495183A (zh) 2004-05-12
US5703078A (en) 1997-12-30
ID30373A (id) 1997-01-23
AR052907A1 (es) 2007-04-11
SI0871631T1 (sl) 2006-04-30
EP0871631A1 (en) 1998-10-21
CN1125824C (zh) 2003-10-29
KR100428335B1 (ko) 2004-06-16
AU6337396A (en) 1997-02-18
WO1997003988A1 (en) 1997-02-06
EP1489082A1 (en) 2004-12-22
TW334436B (en) 1998-06-21
HU226296B1 (hu) 2008-08-28
FI980112A (fi) 1998-01-20
AU699644B2 (en) 1998-12-10
AR038428A2 (es) 2005-01-12
BR9609812B8 (pt) 2014-10-29
CN1277830C (zh) 2006-10-04
DK0871631T3 (da) 2006-03-13
SK285248B6 (sk) 2006-09-07
FI980112A0 (fi) 1998-01-20
HK1017883A1 (en) 1999-12-03
HUP9802221A3 (en) 2000-05-29
CA2225813C (en) 2008-02-26
ZA965908B (en) 1997-01-12
AR038433A2 (es) 2005-01-12
FI20050238A (fi) 2005-03-04
NZ311952A (en) 1999-03-29
PL185007B1 (pl) 2003-01-31
EP0871631B1 (en) 2005-11-30
ES2439569T3 (es) 2014-01-23
BR9612975B8 (pt) 2014-10-29
DK1489082T3 (da) 2013-12-09
PT1489082E (pt) 2013-12-23
EP1400523A3 (en) 2004-04-07
FI115912B (fi) 2005-08-15
AR038429A2 (es) 2005-01-12
EP1489082B1 (en) 2013-11-20
SK284833B6 (sk) 2005-12-01
CZ11098A3 (cs) 1998-06-17
HUP9802221A2 (hu) 1999-02-01
NO980255L (no) 1998-03-20
BR9612963B8 (pt) 2014-10-29
AR038430A2 (es) 2005-01-12
MY113806A (en) 2002-05-31
PL324574A1 (en) 1998-06-08
AR038427A2 (es) 2005-01-12
CA2225813A1 (en) 1997-02-06
BR9609812A (pt) 1999-03-02
BR9612944B8 (pt) 2014-10-29
AR038432A2 (es) 2005-01-12
DE69635524T2 (de) 2006-07-06
BR9612974B8 (pt) 2014-10-29
EP1400523A2 (en) 2004-03-24
FI118471B (fi) 2007-11-30
CN1191537A (zh) 1998-08-26
ES2249783T3 (es) 2006-04-01
NO324287B1 (no) 2007-09-17
DE69635524D1 (de) 2006-01-05
MX9800625A (es) 1998-04-30
JP4122447B2 (ja) 2008-07-23
HK1061242A1 (en) 2004-09-10
US5750695A (en) 1998-05-12

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