BR9609812B8 - Para-herquamidas e marcfortinas antiparasíticas. - Google Patents

Para-herquamidas e marcfortinas antiparasíticas.

Info

Publication number
BR9609812B8
BR9609812B8 BRPI9609812-0B8A BR9609812A BR9609812B8 BR 9609812 B8 BR9609812 B8 BR 9609812B8 BR 9609812 A BR9609812 A BR 9609812A BR 9609812 B8 BR9609812 B8 BR 9609812B8
Authority
BR
Brazil
Prior art keywords
marcfortines
antiparasitic
parameters
antiparasitic parameters
Prior art date
Application number
BRPI9609812-0B8A
Other languages
English (en)
Other versions
BR9609812A (pt
Inventor
Byung H Lee
Michael F Clothier
Original Assignee
Zoetis P & U Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9609812(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zoetis P & U Llc filed Critical Zoetis P & U Llc
Publication of BR9609812A publication Critical patent/BR9609812A/pt
Publication of BR9609812B8 publication Critical patent/BR9609812B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Epoxy Compounds (AREA)
BRPI9609812-0B8A 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas. BR9609812B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21
PCT/US1996/010686 WO1997003988A1 (en) 1995-07-21 1996-06-26 Antiparasitic marcfortines and paraherquamides

Publications (2)

Publication Number Publication Date
BR9609812A BR9609812A (pt) 1999-03-02
BR9609812B8 true BR9609812B8 (pt) 2014-10-29

Family

ID=21695455

Family Applications (7)

Application Number Title Priority Date Filing Date
BRPI9612963-8B8A BR9612963B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9609812-0B8A BR9609812B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612974-3B8A BR9612974B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612972-7B8A BR9612972B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612944-1B8A BR9612944B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas antiparasíticas.
BRPI9612975-1B8A BR9612975B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612973-5B8A BR9612973B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI9612963-8B8A BR9612963B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.

Family Applications After (5)

Application Number Title Priority Date Filing Date
BRPI9612974-3B8A BR9612974B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612972-7B8A BR9612972B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612944-1B8A BR9612944B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas antiparasíticas.
BRPI9612975-1B8A BR9612975B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612973-5B8A BR9612973B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.

Country Status (31)

Country Link
US (2) US5703078A (pt)
EP (3) EP1489082B1 (pt)
JP (2) JP4122447B2 (pt)
KR (1) KR100428335B1 (pt)
CN (2) CN1125824C (pt)
AR (10) AR003466A1 (pt)
AT (1) ATE311390T1 (pt)
AU (1) AU699644B2 (pt)
BR (7) BR9612963B8 (pt)
CA (1) CA2225813C (pt)
CO (1) CO4750664A1 (pt)
CZ (1) CZ296008B6 (pt)
DE (1) DE69635524T2 (pt)
DK (2) DK0871631T3 (pt)
ES (2) ES2439569T3 (pt)
FI (2) FI115912B (pt)
HK (2) HK1017883A1 (pt)
HU (1) HU226296B1 (pt)
ID (1) ID30373A (pt)
MX (1) MX9800625A (pt)
MY (1) MY113806A (pt)
NO (1) NO324287B1 (pt)
NZ (1) NZ311952A (pt)
PL (1) PL185007B1 (pt)
PT (1) PT1489082E (pt)
RU (1) RU2162090C2 (pt)
SI (1) SI0871631T1 (pt)
SK (2) SK285248B6 (pt)
TW (1) TW334436B (pt)
WO (1) WO1997003988A1 (pt)
ZA (1) ZA965908B (pt)

Families Citing this family (44)

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ZA976761B (en) * 1996-09-09 1999-01-29 Upjohn Co 25 Methylene and 24,25-epoxy marcfortines and paraherquamides
WO1998021211A1 (en) * 1996-11-15 1998-05-22 Pharmacia & Upjohn Company 1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents
PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
CA2945453C (en) 2008-11-14 2021-03-02 Merial, Inc. Enantiomerically enriched aryloazol-2-yl cyanoethylamino paraciticidal compounds
AU2009316899B2 (en) 2008-11-19 2015-08-20 Boehringer Ingelheim Animal Health USA Inc. Compositions comprising 1-arylpyrazole alone or in combination with formamidine for the treatment of parasitic infection
US8426460B2 (en) 2008-12-04 2013-04-23 Merial Limited Dimeric avermectin and milbemycin derivatives
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
US8846569B2 (en) 2009-12-04 2014-09-30 Merial Limited Pesticidal bis-organosulfur compounds
MX2020001453A (es) 2009-12-17 2021-07-29 Merial Ltd Compuestos de dihidroazol antiparasiticos y composiciones que comprenden los mismos.
WO2011075592A1 (en) 2009-12-17 2011-06-23 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
MX2013005414A (es) 2010-11-16 2013-08-29 Centre Nat Rech Scient Derivados de monensina novedosos para el tratamiento y prevencion de infecciones por protozoarios.
WO2013003168A1 (en) 2011-06-27 2013-01-03 Merial Limited Novel insect-repellent coumarin derivatives, syntheses, and methods of use
CA2840396C (en) 2011-06-27 2020-07-14 Merial Limited Amido-pyridyl ether compounds and compositions and their use against parasites
TR201903499T4 (tr) 2011-09-12 2019-04-22 Merial Inc Bi̇r i̇zoksazoli̇n akti̇f maddesi̇ni̇ i̇çeren parazi̇ti̇si̇dal bi̇leşi̇mler, bunlarin yöntemleri̇ ve kullanimlari
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
ES2642715T3 (es) 2011-11-17 2017-11-17 Merial, Inc. Composiciones que comprenden un aril pirazol y un imidazol sustituido, procedimientos y utilizaciones de las mismas
EP3351546B1 (en) 2011-12-02 2024-02-14 Boehringer Ingelheim Vetmedica GmbH Long-acting injectable moxidectin formulations
ES2515015B2 (es) 2012-02-06 2016-03-01 Merial Limited Composiciones veterinarias orales parasiticidas que comprenden agentes activos de acción sistémica, métodos y usos de las mismas
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
BR112014026184B1 (pt) 2012-04-20 2019-04-24 Merial, Inc. Composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
LT2922845T (lt) 2012-11-20 2018-09-10 Merial, Inc. Antihelmintiniai junginiai ir kompozicijos ir jų naudojimo būdai
PT3063144T (pt) 2013-11-01 2021-10-28 Boehringer Ingelheim Animal Health Usa Inc Compostos de isoxazolina antiparasitários e pesticidas
NZ726251A (en) 2014-04-17 2017-11-24 Merial Inc Use of malononitrile compounds for protecting animals from parasites
NZ726874A (en) 2014-05-19 2018-03-23 Merial Inc Anthelmintic compounds
ES2723969T3 (es) 2014-06-19 2019-09-04 Merial Inc Composiciones parasiticidas que comprenden derivados de indol, procedimientos y usos de las mismas
US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
PL3298027T3 (pl) 2015-05-20 2021-11-08 Boehringer Ingelheim Animal Health USA Inc. Przeciwrobacze związki depsipeptydów
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
MX2019004266A (es) 2016-10-14 2019-09-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos de vinil isoxazolina pesticidas y parasiticidas.
US11382949B2 (en) 2016-11-16 2022-07-12 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
JP2020530850A (ja) 2017-08-14 2020-10-29 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 殺有害生物および殺寄生生物ピラゾール−イソキサゾリン化合物
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
US20220048903A1 (en) 2018-07-09 2022-02-17 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic Heterocyclic Compounds
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
BR112021016196A2 (pt) 2019-03-01 2021-10-05 Boehringer Ingelheim Animal Health USA Inc. Composições injetáveis de clorsulon, métodos e usos das mesmas
CN113825543A (zh) 2019-03-19 2021-12-21 勃林格殷格翰动物保健美国公司 驱虫的氮杂-苯并噻吩和氮杂-苯并呋喃化合物
PE20231205A1 (es) 2020-05-29 2023-08-17 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos
CN111748503B (zh) * 2020-08-04 2021-12-14 华中农业大学 一种深海独岛枝芽胞杆菌培养基和剂型
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
US20230312207A1 (en) 2022-02-17 2023-10-05 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer

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US5075307A (en) * 1987-07-28 1991-12-24 Merck & Co., Inc. Paraherquamide and dihydroparaherquamide as antihelminthic agents
US4873247A (en) * 1987-11-27 1989-10-10 Goegelman Robert T Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents
US4978656A (en) * 1988-08-12 1990-12-18 Merck & Co., Inc. Synthetic derivatives of paraherquamide
US4866060A (en) * 1988-08-19 1989-09-12 Merck & Co., Inc. Use of the natural product marcfortines as antiparasitic agents
US4923867A (en) * 1988-08-24 1990-05-08 Merck & Co., Inc. Synthetic marcfortine derivatives useful as antiparasitic agents
NZ233043A (en) * 1989-03-30 1992-09-25 Merck & Co Inc Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide
IE904606A1 (en) * 1989-12-21 1991-07-03 Beecham Group Plc Novel products
GB9014194D0 (en) * 1990-06-26 1990-08-15 Pfizer Ltd Antiparasitic agents
WO1992022555A1 (en) * 1991-06-17 1992-12-23 Beecham Group Plc Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents
TW410227B (en) * 1993-06-16 2000-11-01 Upjohn Co 14-substituted marcfortines and derivatives useful as antiparasitic agents

Also Published As

Publication number Publication date
AR038430A2 (es) 2005-01-12
FI115912B (fi) 2005-08-15
AR038433A2 (es) 2005-01-12
ATE311390T1 (de) 2005-12-15
BR9609812A (pt) 1999-03-02
MX9800625A (es) 1998-04-30
AR038431A2 (es) 2005-01-12
NO980255L (no) 1998-03-20
ES2439569T3 (es) 2014-01-23
CN1495183A (zh) 2004-05-12
EP1489082A1 (en) 2004-12-22
NO324287B1 (no) 2007-09-17
HK1061242A1 (en) 2004-09-10
US5750695A (en) 1998-05-12
AR003466A1 (es) 1998-08-05
TW334436B (en) 1998-06-21
DE69635524T2 (de) 2006-07-06
SK284833B6 (sk) 2005-12-01
BR9612963B8 (pt) 2014-10-29
ES2249783T3 (es) 2006-04-01
DK1489082T3 (da) 2013-12-09
BR9612975B8 (pt) 2014-10-29
KR100428335B1 (ko) 2004-06-16
US5703078A (en) 1997-12-30
AR038429A2 (es) 2005-01-12
DK0871631T3 (da) 2006-03-13
HUP9802221A3 (en) 2000-05-29
EP0871631A1 (en) 1998-10-21
SK5498A3 (en) 1998-08-05
PL185007B1 (pl) 2003-01-31
AR038434A2 (es) 2005-01-12
BR9612973B8 (pt) 2014-10-29
PT1489082E (pt) 2013-12-23
HUP9802221A2 (hu) 1999-02-01
JP4122447B2 (ja) 2008-07-23
NZ311952A (en) 1999-03-29
WO1997003988A1 (en) 1997-02-06
CN1277830C (zh) 2006-10-04
DE69635524D1 (de) 2006-01-05
EP0871631B1 (en) 2005-11-30
FI20050238A (fi) 2005-03-04
SK285248B6 (sk) 2006-09-07
EP1400523A3 (en) 2004-04-07
AR038427A2 (es) 2005-01-12
FI980112A0 (fi) 1998-01-20
AR038428A2 (es) 2005-01-12
HK1017883A1 (en) 1999-12-03
CA2225813C (en) 2008-02-26
CA2225813A1 (en) 1997-02-06
HU226296B1 (hu) 2008-08-28
AR052907A1 (es) 2007-04-11
EP1489082B1 (en) 2013-11-20
CZ296008B6 (cs) 2005-12-14
CZ11098A3 (cs) 1998-06-17
BR9612944B8 (pt) 2014-10-29
MY113806A (en) 2002-05-31
NO980255D0 (no) 1998-01-20
FI118471B (fi) 2007-11-30
FI980112A (fi) 1998-01-20
AR038432A2 (es) 2005-01-12
RU2162090C2 (ru) 2001-01-20
EP1400523A2 (en) 2004-03-24
CN1125824C (zh) 2003-10-29
BR9612972B8 (pt) 2014-10-29
BR9612974B8 (pt) 2014-10-29
ZA965908B (en) 1997-01-12
AU699644B2 (en) 1998-12-10
JPH11509550A (ja) 1999-08-24
AU6337396A (en) 1997-02-18
CO4750664A1 (es) 1999-03-31
PL324574A1 (en) 1998-06-08
SI0871631T1 (sl) 2006-04-30
CN1191537A (zh) 1998-08-26
JP2008007516A (ja) 2008-01-17
ID30373A (id) 1997-01-23

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 15/01/2008, OBSERVADAS AS CONDICOES LEGAIS.

B22O Other matters related to patents and certificates of addition of invention: legal action concerning patent

Free format text: INPI-50400.061581/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO 0132366-77.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: PHARMACIA AND UPJOHN COMPANY, PASTEUR MERIEUX SERUMS ET VACCINS S.A.NOVEN PHARMACEUTICALS, INC.

B25D Requested change of name of applicant approved

Owner name: PHARMACIA AND UPJOHN COMPANY LLC (US)

B25A Requested transfer of rights approved

Owner name: PAH PANDU LLC (US)

B25D Requested change of name of applicant approved

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