SG10201704665QA - Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof - Google Patents

Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof

Info

Publication number
SG10201704665QA
SG10201704665QA SG10201704665QA SG10201704665QA SG10201704665QA SG 10201704665Q A SG10201704665Q A SG 10201704665QA SG 10201704665Q A SG10201704665Q A SG 10201704665QA SG 10201704665Q A SG10201704665Q A SG 10201704665QA SG 10201704665Q A SG10201704665Q A SG 10201704665QA
Authority
SG
Singapore
Prior art keywords
methods
benzimidazole derivatives
parasiticidal compositions
parasiticidal
compositions
Prior art date
Application number
SG10201704665QA
Inventor
Charles Q Meng
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Publication of SG10201704665QA publication Critical patent/SG10201704665QA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • A61P33/12Schistosomicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10Radicals substituted by halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
SG10201704665QA 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof SG10201704665QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261635961P 2012-04-20 2012-04-20

Publications (1)

Publication Number Publication Date
SG10201704665QA true SG10201704665QA (en) 2017-07-28

Family

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Family Applications (3)

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SG10201700291VA SG10201700291VA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
SG10201704665QA SG10201704665QA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
SG11201406730RA SG11201406730RA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof

Family Applications Before (1)

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SG10201700291VA SG10201700291VA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201406730RA SG11201406730RA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof

Country Status (24)

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US (3) US9000187B2 (en)
EP (3) EP3453702A3 (en)
JP (4) JP6161173B2 (en)
KR (3) KR102114598B1 (en)
CN (4) CN107353254A (en)
AR (1) AR090766A1 (en)
AU (2) AU2013249217B2 (en)
BR (3) BR112014026184B1 (en)
CA (2) CA3059936A1 (en)
CL (3) CL2014002831A1 (en)
CO (1) CO7151497A2 (en)
EA (1) EA028430B1 (en)
ES (1) ES2703535T3 (en)
HK (1) HK1211580A1 (en)
IL (3) IL235107A (en)
MX (3) MX367536B (en)
NZ (3) NZ701185A (en)
PH (1) PH12014502345A1 (en)
PT (1) PT2895465T (en)
SG (3) SG10201700291VA (en)
UA (1) UA115981C2 (en)
UY (1) UY34761A (en)
WO (1) WO2013158894A1 (en)
ZA (1) ZA201407605B (en)

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WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
EP4272550A2 (en) 2016-03-31 2023-11-08 Boehringer Ingelheim Animal Health USA Inc. Tag system for tracking an animal
CN106496037A (en) * 2016-10-20 2017-03-15 上海毕得医药科技有限公司 A kind of synthetic method of 1,4 diiodo-, 2 methoxyl group, 5 nitrobenzene
KR102147235B1 (en) * 2018-05-18 2020-08-24 연세대학교 산학협력단 Heteroaryl compound exhibiting luminescent, ferroelectric and piezoelectric properties, and electronic device containing the same
GB201811695D0 (en) * 2018-07-17 2018-08-29 Salvensis Compounds for use in the treatment of fascioliasis
WO2024026359A1 (en) * 2022-07-26 2024-02-01 The Board Of Trustees Of The University Of Illinois Compounds and methods for the treatment of diseases associated with parasitic worms

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PH12014502345B1 (en) 2014-12-22
JP2015516977A (en) 2015-06-18
SG10201700291VA (en) 2017-03-30
BR122015032742B1 (en) 2020-04-07
US9359305B2 (en) 2016-06-07
MX2014012713A (en) 2015-01-19
KR20200000470A (en) 2020-01-02
NZ709589A (en) 2015-10-30
BR112014026184B1 (en) 2019-04-24
BR122015032741A2 (en) 2019-08-27
CN107353254A (en) 2017-11-17
JP2016155837A (en) 2016-09-01
JP2017119716A (en) 2017-07-06
BR112014026184A2 (en) 2017-06-27
PH12014502345A1 (en) 2014-12-22
US20130281392A1 (en) 2013-10-24
JP6213852B2 (en) 2017-10-18
KR102114598B1 (en) 2020-05-25
JP2016106154A (en) 2016-06-16
US20160251317A1 (en) 2016-09-01
CN105884693A (en) 2016-08-24
BR122015032742A2 (en) 2018-12-11
EP3453702A2 (en) 2019-03-13
NZ711847A (en) 2015-11-27
EP3763706A1 (en) 2021-01-13
KR102160889B1 (en) 2020-09-28
MX345971B (en) 2017-02-28
CL2014002831A1 (en) 2014-12-12
CL2018003596A1 (en) 2019-01-25
BR122015032741B1 (en) 2019-11-26
US9695129B2 (en) 2017-07-04
US20150166485A1 (en) 2015-06-18
CA2870956C (en) 2020-03-31
US9000187B2 (en) 2015-04-07
UA115981C2 (en) 2018-01-25
SG11201406730RA (en) 2014-11-27
NZ701185A (en) 2015-08-28
CL2017001239A1 (en) 2017-12-11
MX367536B (en) 2019-08-26
CO7151497A2 (en) 2014-12-29
KR20150002853A (en) 2015-01-07
UY34761A (en) 2013-11-29
EP2895465B1 (en) 2018-10-03
CN105732511A (en) 2016-07-06
ZA201407605B (en) 2015-11-25
ES2703535T3 (en) 2019-03-11
IL251177B (en) 2018-03-29
WO2013158894A1 (en) 2013-10-24
EP3453702A3 (en) 2019-05-15
IL242980A (en) 2017-08-31
KR102160836B1 (en) 2020-09-28
CN104395295B (en) 2018-03-06
AU2013249217A1 (en) 2014-11-06
CA2870956A1 (en) 2013-10-24
CN104395295A (en) 2015-03-04
AR090766A1 (en) 2014-12-03
EP2895465A1 (en) 2015-07-22
EA201401160A1 (en) 2015-04-30
AU2013249217B2 (en) 2017-04-27
IL251177A0 (en) 2017-05-29
EA028430B1 (en) 2017-11-30
AU2017202719A1 (en) 2017-05-18
PT2895465T (en) 2019-01-16
HK1211580A1 (en) 2016-05-27
JP6246405B2 (en) 2017-12-13
IL235107A (en) 2017-09-28
JP6124321B2 (en) 2017-05-10
CN105732511B (en) 2018-08-17
KR20190114002A (en) 2019-10-08
JP6161173B2 (en) 2017-07-12
CN105884693B (en) 2019-11-01
CA3059936A1 (en) 2013-10-24
MX351636B (en) 2017-10-23

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