CN1649551A - 药物释放型血管内支架和治疗再狭窄的方法 - Google Patents
药物释放型血管内支架和治疗再狭窄的方法 Download PDFInfo
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- CN1649551A CN1649551A CNA038093111A CN03809311A CN1649551A CN 1649551 A CN1649551 A CN 1649551A CN A038093111 A CNA038093111 A CN A038093111A CN 03809311 A CN03809311 A CN 03809311A CN 1649551 A CN1649551 A CN 1649551A
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Abstract
Description
装置说明 | (B/A)比(平均) | 随访时间 | 平均内腔损失(mm) | 新内膜面积(mm2) | 支架号 |
裸金属支架 | 1.33 | 28 | 1.69 | 5.89 | 31,39,40,45,47,50 |
聚合物涂层支架 | 1.36 | 28 | 2.10 | 5.82 | 32,41,43,48,51,60 |
R-高 | 1.39 | 28 | 1.07 | 3.75 | 42,44,49,65,69,73 |
R-低 | 1.42 | 28 | 0.99 | 2.80 | 52,56,61,64,68,72 |
C-高 | 1.37 | 28 | 0.84 | 3.54 | 54,55,59,63 |
C-低 | 1.36 | 28 | 1.54 | 3.41 | 53,57,58,62,66,70,74 |
C-U高 | 1.36 | 28 | 0.85 | 2.97 | 67,75,92,103 |
装置说明 | (B/A)比 | 植入后的天数 | 平均内腔损失(mm) | 新内膜面积(mm2) | 支架号 |
裸金属支架 | 1.14 | 28 | 0.95 | 2.89 | 20,22,26,29 |
裸金属支架 | 1.13 | 90 | 76,80,84,87,91 | ||
C-U高 | 1.15 | 28 | 0.60 | 2.14 | 94,96,98,102 |
C-U低 | 1.09 | 28 | 0.49 | 2.26 | 93,95,97,100,101 |
C-U高 | 1.15 | 90 | 77,81,85,86,90 |
装置说明 | 损伤度 | 随访时间 | 新内膜面积(mm2) | 狭窄面积(%) | 支架号 |
裸金属支架 | 1.9 | 28 | 5.89 | 0.72 | 31,39,40,45,47,50 |
聚合物涂层支架 | 2.11 | 28 | 5.82 | 0.70 | 32,41,43,48,51,60 |
R-高 | 2.10 | 28 | 3.75 | 0.55 | 42,44,49,65,69,73 |
R-低 | 1.90 | 28 | 2.80 | 0.43 | 52,56,61,64,68,72 |
C-高 | 1.89 | 28 | 3.54 | 0.38 | 54,55,59,63 |
C-低 | 2.1 | 28 | 3.41 | 0.53 | 53,57,58,62,66,70,74 |
C-U高 | 2.13 | 28 | 2.97 | 0.45 | 67,75,92,103 |
装置说明 | 血管过度拉伸(%) | 平均后期损失(mm) | 标准偏差(mm) | 新内膜截面面积(mm2) |
S-支架裸金属对照 | 33.5%±9.2% | 1.80 | ±0.5 | 7.6 |
S-支架仅涂聚合物 | 34.9%±4.8% | 2.02 | ±0.8 | 8.5 |
S-支架聚合物/雷帕霉素(325mg) | 32.9%±10.1% | 0.66 | ±0.2 | 3.27(对照的-57%) |
S-支架聚合物/依维莫司(325mg) | 36.8%±8.5% | 0.74 | ±0.3 | 3.61(对照的-50%) |
PS支架BARE*对照 | 10-20% | 1.19 | --- | 4.5 |
PS支架仅涂聚合物 | 10-20% | 1.38 | --- | 5.0 |
PS雷帕霉素洗脱支架*166mg | 10-20% | 0.70 | --- | 2.9(对照的-33.5%) |
PS雷帕霉素洗脱支架*166mg(缓释) | 10-20% | 0.67 | --- | 2.8(对照的-37.7%) |
PS雷帕霉素洗脱支架*450mg | 10-20% | 0.75 | --- | 3.1(对照的-31.1%) |
Claims (13)
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US10/133,814 US6939376B2 (en) | 2001-11-05 | 2002-04-24 | Drug-delivery endovascular stent and method for treating restenosis |
US10/133,814 | 2002-04-24 | ||
PCT/US2003/012750 WO2003090818A2 (en) | 2002-04-24 | 2003-04-24 | Drug-delivery endovascular stent and method for treating restenosis |
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CNA03809309XA Pending CN1735402A (zh) | 2002-04-24 | 2003-04-24 | 含大环三烯化合物的聚合物组合物 |
CN038093111A Expired - Lifetime CN1649551B (zh) | 2002-04-24 | 2003-04-24 | 药物释放型血管内支架 |
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CNA03809309XA Pending CN1735402A (zh) | 2002-04-24 | 2003-04-24 | 含大环三烯化合物的聚合物组合物 |
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AU (3) | AU2003231757B2 (zh) |
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- 2003-04-24 CN CNA03809309XA patent/CN1735402A/zh active Pending
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2011
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2012
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2014
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