CN1217029A - 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法 - Google Patents

从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法 Download PDF

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Publication number
CN1217029A
CN1217029A CN97194210A CN97194210A CN1217029A CN 1217029 A CN1217029 A CN 1217029A CN 97194210 A CN97194210 A CN 97194210A CN 97194210 A CN97194210 A CN 97194210A CN 1217029 A CN1217029 A CN 1217029A
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biomass
oil
arbitrary
polyunsaturated fatty
pufa
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CN97194210A
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Chinese (zh)
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H·L·比尔
J·H·沃尔夫
A·沙普
J·M·J·维瑟
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DSM Delft BV
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Gist Brocades BV
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    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
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    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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CN97194210A 1996-03-28 1997-03-21 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法 Pending CN1217029A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP96200835 1996-03-28
EP96200835.5 1996-03-28
EP96200837.1 1996-03-28
EP96200837 1996-03-28

Publications (1)

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CN1217029A true CN1217029A (zh) 1999-05-19

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CN97194210A Pending CN1217029A (zh) 1996-03-28 1997-03-21 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法

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EP (6) EP2251411A3 (https=)
JP (10) JP2000508888A (https=)
CN (1) CN1217029A (https=)
AR (1) AR006425A1 (https=)
AT (1) ATE328104T1 (https=)
AU (1) AU731785B2 (https=)
CA (3) CA2788661C (https=)
DE (1) DE69735997T3 (https=)
DK (1) DK0894142T4 (https=)
ES (1) ES2267137T5 (https=)
ID (1) ID16504A (https=)
WO (1) WO1997037032A2 (https=)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100575497C (zh) * 2002-06-19 2009-12-30 帝斯曼知识产权资产管理有限公司 包含多不饱和脂肪酸的微生物油的制备
CN101981201A (zh) * 2006-08-01 2011-02-23 加拿大海洋营养食品有限公司 产油微生物及改良这些微生物的方法
CN101106913B (zh) * 2005-01-26 2011-11-16 努特诺瓦营养产品及食品成分有限公司 无色涡鞭毛藻抗氧化提取物的生产和用途
CN102325892A (zh) * 2008-12-01 2012-01-18 赢泰医药科技发展有限公司 利用粘细菌生产omega-3脂肪酸
CN102597242A (zh) * 2009-06-08 2012-07-18 罗特哈姆斯泰德研究有限公司 新脂肪酸延伸组合物及其用途
CN102665431A (zh) * 2009-11-03 2012-09-12 帝斯曼知识产权资产管理有限公司 包含细胞和具有至少20个碳原子的多不饱和脂肪酸(lc-pufa)的组合物
CN103282474A (zh) * 2010-04-22 2013-09-04 纳幕尔杜邦公司 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法
CN103357199A (zh) * 2003-12-30 2013-10-23 帝斯曼知识产权资产管理有限公司 脱气方法
CN101837139B (zh) * 2002-06-19 2014-05-28 帝斯曼知识产权资产管理有限公司 微生物油
CN103957722A (zh) * 2011-12-01 2014-07-30 国际壳牌研究有限公司 从微生物质采收脂类的方法
CN104982920A (zh) * 2009-11-03 2015-10-21 帝斯曼知识产权资产管理有限公司 包含细胞和具有至少20个碳原子的多不饱和脂肪酸(lc-pufa)的组合物
CN106367198A (zh) * 2009-04-14 2017-02-01 泰拉瑞亚控股公司 微生物油提取和分离方法
CN112004919A (zh) * 2018-03-30 2020-11-27 帝斯曼知识产权资产管理有限公司 通过肉汤洗涤减少乳液的方法

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2658233B2 (ja) * 1988-08-11 1997-09-30 日本電気株式会社 超音波モータとその駆動方法
CN1217029A (zh) * 1996-03-28 1999-05-19 吉斯特-布罗卡迪斯股份有限公司 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法
JP3792309B2 (ja) 1996-08-30 2006-07-05 サントリー株式会社 不飽和脂肪酸含有油脂の製造方法
TW533235B (en) * 1997-06-11 2003-05-21 Idemitsu Petrochemical Co Method for extracting fat-soluble components from microbial cells
TR200003712T2 (tr) 1998-06-17 2001-04-20 Dsm N.V. Denizde yaşayan hayvanların yemlerinde kullanıma yönelik mikrobik arakidonik asit (ARA)
EP1121115B2 (en) 1998-10-15 2010-08-18 DSM IP Assets B.V. Pufa supplements
FR2795958B1 (fr) * 1999-07-09 2001-09-28 Codif Internat Sa Produit cosmetique qui contient un principe actif pour lutter contre l'adiposite
FR2795959B1 (fr) * 1999-07-09 2005-02-25 Codif Internat Sa Produit cosmetique ou pharmaceutique du type qui contient un principe actif pour lutter contre d'adiposite
US6338866B1 (en) * 2000-02-15 2002-01-15 Applied Food Biotechnology, Inc. Pet foods using algal or fungal waste containing fatty acids
EP1178118A1 (en) * 2000-08-02 2002-02-06 Dsm N.V. Isolation of microbial oils
ES2324640T3 (es) * 2001-03-09 2009-08-12 Societe Des Produits Nestle S.A. Aceite que contiene un o unos acido(s) graso(s) poliin-saturado(s) de cadena larga resultante de una biomasa, procedimiento de preparacion, alimento, composicion nutricional, cosmetica o farmaceutica que lo contiene.
EP1515616A4 (en) * 2002-03-19 2005-12-28 Advanced Bionutrition Corp ARACHIDOIC ACID-CONTAINING MICRO-ALPINE FEED, THEIR PREPARATION AND THEIR USE
US9101151B2 (en) 2002-05-03 2015-08-11 Dsm Ip Assets B.V. High-quality lipids produced by enzymatic liberation from biomass
ES2312513T3 (es) * 2002-09-04 2009-03-01 Nestec S.A. Procedimiento para la preparacion de un aceite conteniendo uno o unos acidos grasos poliinsaturados de cadena larga proviniendo de biomasa, alimento, composicion nutricional, cosmetica o farmaceutica conteniendo dicho aceite.
EP1549753B1 (en) * 2002-10-11 2010-09-08 Nippon Suisan Kaisha, Ltd. Process for producing microbial fat or oil having lowered unsaponifiable matter content
EA039406B1 (ru) * 2002-12-18 2022-01-24 ДСМ Ай Пи ЭССЕТС Б.В. Способ пастеризации микробных клеток и масла из микробных клеток
DE102004017370A1 (de) * 2004-04-08 2005-10-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh PUFA-PKS Gene aus Ulkenia
JP2006061021A (ja) * 2004-08-24 2006-03-09 Suntory Ltd １種類の高度不飽和脂肪酸残基３個から成るトリグリセライドの製造方法、およびその利用
WO2006052664A2 (en) * 2004-11-04 2006-05-18 Monsanto Technology Llc Processes for preparation of oil compositions
US7550286B2 (en) * 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
DE102004062141A1 (de) 2004-12-23 2006-07-06 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Verfahren zur Herstellung eines Rohöls aus Gemischen von Mikroorganismen und Pflanzen, das so hergestellte Öl sowie die spezifischen Verwendungen des so hergestellten und gegebenenfalls zusätzlich raffinierten Öls
US8241868B2 (en) 2005-02-08 2012-08-14 Nippon Suisan Kaisha, Ltd. Production of polyunsaturated fatty acids using cell treatment method
JP4849806B2 (ja) * 2005-02-08 2012-01-11 日本水産株式会社 新規な菌体処理方法を用いた高度不飽和脂肪酸の製造方法
AU2006247618A1 (en) * 2005-05-12 2006-11-23 Martek Biosciences Corporation Biomass hydrolysate and uses and production thereof
AU2006325040B2 (en) 2005-06-07 2012-04-19 Dsm Nutritional Products Ag Eukaryotic microorganisms for producing lipids and antioxidants
US8221743B2 (en) 2006-12-22 2012-07-17 Novozymes A/S Use of polypeptides against diseases caused by protozoans
US9896642B2 (en) 2008-10-14 2018-02-20 Corbion Biotech, Inc. Methods of microbial oil extraction and separation
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
MX2011009750A (es) 2009-03-19 2011-09-29 Martek Biosciences Corp Traustoquitridos, composiciones de acidos grasos y metodos de produccion y usos de los mismos.
WO2010111132A2 (en) 2009-03-27 2010-09-30 Bend Research, Inc. Spray-drying process
WO2011066419A2 (en) * 2009-11-25 2011-06-03 Kuehnle Agrosystems, Inc. Enrichment of process feedstock
TWI411677B (zh) * 2009-12-21 2013-10-11 Ind Tech Res Inst 連續式微藻萃取裝置、連續萃取與脫水破裂的方法
US9924733B2 (en) 2010-01-19 2018-03-27 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
CN107794230B (zh) 2010-03-11 2021-10-12 帝斯曼知识产权资产管理有限公司 酵母菌株及其在脂类产生中的用途
EP2576801B1 (en) 2010-06-01 2019-10-02 DSM IP Assets B.V. Extraction of lipid from cells and products therefrom
MX2013000892A (es) * 2010-07-26 2013-04-03 Sapphire Energy Inc Proceso para la recuperacion de compuestos oleaginosos a partir de biomasa.
PT2611530T (pt) 2010-09-03 2019-05-09 Bend Res Inc Aparelho de secagem por pulverização e métodos de utilização do mesmo
US9084976B2 (en) 2010-09-03 2015-07-21 Bend Research, Inc. Spray-drying apparatus and methods of using the same
WO2012040502A1 (en) 2010-09-24 2012-03-29 Bend Research, Inc. High-temperature spray drying process and apparatus
WO2012109545A2 (en) * 2011-02-11 2012-08-16 E. I. Du Pont De Nemours And Company Method for obtaining a lipid-containing composition from microbial biomass
AU2012285806B2 (en) 2011-07-21 2017-09-14 Dsm Ip Assets B.V. Fatty acid compositions
EP2762008A1 (de) 2013-02-05 2014-08-06 Evonik Industries AG Verbesserung der Bioverfügbarkeit von Wertstoffen aus Mikroorganismen durch Verwendung eines Rotor-Stator Systems für den Zellaufschluss
EP2953480B1 (de) 2013-02-05 2020-06-03 Evonik Operations GmbH Verbesserung der bioverfügbarkeit von wertstoffen aus mikroorganismen
NZ743055A (en) 2013-03-08 2020-03-27 Xyleco Inc Equipment protecting enclosures
EP2970926B1 (en) 2013-03-13 2018-01-31 DSM Nutritional Products AG Engineering microorganisms
CN105324471A (zh) * 2013-06-25 2016-02-10 国际壳牌研究有限公司 由微生物生物质生产脂肪酸酯的直接方法
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
US20160194598A1 (en) * 2013-07-25 2016-07-07 Roquette Freres Method for optimising the production efficiency, organoleptic quality and stability over time of a protein-rich microalgae biomass
PL3083546T3 (pl) 2013-12-20 2022-05-16 Dsm Ip Assets B.V. Sposoby wytwarzania oleju mikrobiologicznego z komórek mikrobiologicznych
CN105829539B (zh) 2013-12-20 2023-11-10 帝斯曼营养品股份公司 从微生物中回收油的方法
NZ721413A (en) 2013-12-20 2022-05-27 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
CN105939710B (zh) 2013-12-20 2020-05-08 帝斯曼知识产权资产管理有限公司 用于从微生物细胞获得微生物油的方法
SI3083976T1 (sl) * 2013-12-20 2020-10-30 Xellia Pharmaceuticals Aps Postopek priprave tiakumicina B
AU2014369040B2 (en) 2013-12-20 2019-12-05 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
AR098895A1 (es) 2013-12-20 2016-06-22 Dsm Ip Assets Bv Proceso para obtener aceite microbiano a partir de células microbianas
FI3626806T3 (fi) 2013-12-20 2024-08-22 Mara Renewables Corp Menetelmiä öljyn talteenottamiseksi mikro-organismeista
JP6514867B2 (ja) * 2014-09-05 2019-05-15 花王株式会社 不飽和を含むアセチルスフィンゴイドの製造方法
WO2016050552A1 (de) 2014-10-02 2016-04-07 Evonik Degussa Gmbh Verfahren zur herstellung einer pufas enthaltenden biomasse mit hoher zellstabilität
US11464244B2 (en) 2014-10-02 2022-10-11 Evonik Operations Gmbh Feedstuff of high abrasion resistance and good stability in water, containing PUFAs
US10619175B2 (en) 2014-10-02 2020-04-14 Evonik Operations Gmbh Process for producing a PUFA-containing feedstuff by extruding a PUFA-containing biomass
ES2900848T5 (en) 2014-10-02 2025-09-25 Evonik Operations Gmbh Method for preparing an animal feed
WO2016067132A1 (en) 2014-10-31 2016-05-06 Bend Research Inc. Process for forming active domains dispersed in a matrix
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
EP3322796A4 (en) 2015-07-13 2019-03-27 Mara Renewables Corporation IMPROVEMENT OF MICROGENONAL FLUID CHANGES OF XYLOSE
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
FR3053052B1 (fr) 2016-06-28 2021-02-12 Fermentalg Microalgue modifiee pour une production enrichie en tag
JP6998935B2 (ja) 2016-07-13 2022-01-18 エボニック オペレーションズ ゲーエムベーハー 溶解された脂質含有バイオマスから脂質を分離する方法
WO2018011275A1 (en) 2016-07-13 2018-01-18 Evonik Degussa Gmbh Method for isolating lipids from lipid-containing cells
AU2017297760B2 (en) 2016-07-13 2021-09-23 Dsm Ip Assets B.V. Method of separating lipids from a lysed lipids containing biomass
CN110087481A (zh) 2016-12-15 2019-08-02 帝斯曼知识产权资产管理有限公司 包含硅酸盐和含具有至少20个碳原子的多不饱和脂肪酸(lc-pufa)的微生物细胞和/或植物细胞的共混物制剂
EP3559206B1 (en) 2016-12-22 2025-12-03 Mara Renewables Corporation Methods for producing biomass rich in dha, palmitic acid and protein using a eukaryotic microorganism
WO2018122057A1 (en) 2016-12-27 2018-07-05 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
RU2744913C2 (ru) 2016-12-27 2021-03-17 Эвоник Оперейшенс ГмбХ Способ выделения липидов из липидсодержащей биомассы
CN110267654A (zh) * 2017-02-22 2019-09-20 嘉吉公司 含dha的油的纯化
US11814665B2 (en) 2017-08-17 2023-11-14 Evonik Operations Gmbh Enhanced production of lipids by limitation of at least two limiting nutrient sources
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
WO2019048327A1 (en) 2017-09-05 2019-03-14 Evonik Degussa Gmbh METHOD FOR SEPARATING LIPIDS IN A BIOMASS CONTAINING LYDE LIPIDS
EA202090440A1 (ru) 2017-09-21 2020-07-17 Эвоник Оперейшенс ГмбХ Улучшенное получение липидов путем ограничения по меньшей мере двух источников лимитирующих питательных веществ
WO2019121752A1 (en) 2017-12-20 2019-06-27 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019122030A1 (en) 2017-12-22 2019-06-27 Dsm Ip Assets B.V. Method of separating lipids from a lysed lipids containing biomass
WO2019185910A2 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Novel use of substituted 2h-chromens and their derivatives
WO2019185938A2 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Novel use of substituted chroman-6-ols with extended lipophilic side chains
WO2019185941A1 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Novel use of substituted chroman-6-ols with extended lipophilic side chains
WO2019185891A1 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Novel use of substituted chroman-6-ols
WO2019185939A1 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Use of twin-chromanols as antioxidants in oil
WO2019185940A1 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Use of twin-chromanols as antioxidants
WO2019185889A1 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Novel use of carnosic acid
US20210030022A1 (en) 2018-03-29 2021-02-04 Dsm Ip Assets B.V. Novel use of substituted chroman-6-ols
WO2019185904A1 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Chroman-6-ols with an extended lipophilic side chain in position 2, their manufacture and use
EP3818136A1 (en) 2018-03-29 2021-05-12 DSM IP Assets B.V. Novel use of substituted 2h-chromens and their derivatives
WO2019185942A1 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Use of tocotrienols as antioxidants
WO2019185888A1 (en) 2018-03-29 2019-10-03 Dsm Ip Assets B.V. Novel use of tocopherols
WO2019219396A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
EP3794097B1 (en) 2018-05-15 2024-10-23 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
FR3085962B1 (fr) 2018-09-14 2021-06-18 Fermentalg Procede d'extracton d'une huile riche en pufa
US20220017929A1 (en) 2018-11-09 2022-01-20 Evonik Operations Gmbh Method for producing a biomass with an increased content of polyunsaturated fatty acids
CA3118657A1 (en) 2018-11-09 2020-05-14 Evonik Operations Gmbh Method for producing a biomass which can be easily broken down and which has an increased content of polyunsaturated fatty acids
FR3103355B1 (fr) 2019-11-26 2024-05-31 Polaris Composition d’huile de micro-organismes enrichie en acides gras polyinsaturés
MX2022011034A (es) * 2020-03-06 2022-10-13 The Protein Brewery B V Pasteurizacion de biomasa microbiana apta para aplicaciones alimentarias.
AU2021231308A1 (en) * 2020-03-06 2022-09-22 The Protein Brewery B.V. Improved single-cell protein production using antioxidants
MX2022012322A (es) 2020-04-03 2022-11-10 Mara Renewables Corp Aceites microbianos con niveles altos de ácidos grasos omega-3.
EP3933016A1 (en) 2020-06-30 2022-01-05 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass
EP4493707A1 (en) 2022-03-18 2025-01-22 Purac Biochem B.V. Method for reducing fermentation broth viscosity

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3106571A (en) * 1955-10-14 1963-10-08 Thomas C Fisher Physico-mechanical process of obtaining high quality cocoanut oil
GB882634A (en) * 1958-05-09 1961-11-15 Rose Downs & Thompson Ltd An improved process for the preparation of vegetable matter for solvent extraction
US3297731A (en) * 1963-05-06 1967-01-10 Ralston Purina Co Method of pelletizing and extracting oils from oleaginous comminuted matter
DE1923529A1 (de) * 1968-05-29 1969-12-04 Ingtech Zentralbuero Veb Verfahren zur Aufarbeitung eines mikroorganismenhaltigen Produktes
GB1411450A (en) * 1972-12-19 1975-10-22 British Petroleum Co Process for the purification of a micro-organism product
GB1466853A (en) * 1973-05-22 1977-03-09 Simon Rosedowns Ltd Extraction
US3958027A (en) * 1974-06-14 1976-05-18 Simon-Rosedowns Limited Extraction
US4056638A (en) * 1975-06-16 1977-11-01 E. I. Du Pont De Nemours And Company Dielectric drying of fungal material and resultant textured product
DD150627A1 (de) * 1980-05-07 1981-09-09 Klaus Triems Verfahren zur gewinnung und loesungsmittelextraktion von feststoffen
DE3161370D1 (en) * 1980-08-13 1983-12-15 Ici Plc Extraction of poly(beta-hydroxy butyric acid)
JPS59190948A (ja) * 1983-04-14 1984-10-29 ルセル―ユクラフ 新規なトリグリセリド、その製造法、食餌療法及び治療法への使用並びにそれを含む組成物
DE3470061D1 (en) * 1984-02-09 1988-04-28 Agency Ind Science Techn A method for the preparation of a fungal body and a lipid rich in gamma-linolenic acid therefrom
US5411873A (en) * 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
GB8413837D0 (en) * 1984-05-31 1984-07-04 Simon Rosedowns Ltd Preparing vegetable oil seed meal
JPS6123699A (ja) * 1984-07-12 1986-02-01 鐘淵化学工業株式会社 高度不飽和脂肪酸の安定化方法
DE3587044T2 (de) * 1985-01-22 1993-06-03 Japan As Represented By Direct Verfahren zur herstellung von lipiden aus fungusmassen.
GB8606524D0 (en) * 1986-03-17 1986-04-23 Mini Of Agricultural Fisheries Deactivating heat stable enzymes
US4944954A (en) * 1986-04-23 1990-07-31 Epe Incorporated Vegetable oil extraction process
FR2599597B1 (fr) * 1986-06-10 1990-04-27 Croix Fils Ets Procede et installation pour l'obtention de farine alimentaire a partir de graines oleagineuses
JPS63253049A (ja) * 1987-04-09 1988-10-20 Kanegafuchi Chem Ind Co Ltd トリグリセライドの精製法
JPS6438007A (en) † 1987-04-28 1989-02-08 Lion Corp Skin external preparation
JPH0716425B2 (ja) * 1987-05-20 1995-03-01 花王株式会社 油脂類のエステル交換反応方法
JP2549399B2 (ja) * 1987-11-25 1996-10-30 マルハ株式会社 高度不飽和脂肪酸トリグリセリド及びエステルの精製方法
JP2746371B2 (ja) * 1987-12-21 1998-05-06 サントリー株式会社 ビスホモ−γ−リノレン酸及びこれを含有する脂質の製造方法
JPH01207257A (ja) * 1988-02-15 1989-08-21 Nippon Oil & Fats Co Ltd α−リノレン酸の分離法
JPH062068B2 (ja) * 1988-07-06 1994-01-12 出光石油化学株式会社 ω６系不飽和脂胞酸含有リン脂質の製造法
US5340594A (en) * 1988-09-07 1994-08-23 Omegatech Inc. Food product having high concentrations of omega-3 highly unsaturated fatty acids
US5340742A (en) * 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
JP2664452B2 (ja) * 1988-12-23 1997-10-15 サントリー株式会社 魚貝類用餌料
US5935828A (en) * 1989-05-01 1999-08-10 Opta Food Ingredients, Inc. Enzymatic production of monoglycerides containing omega-3 unsaturated fatty acids
US5158798A (en) * 1990-02-05 1992-10-27 Pfizer Inc. Low-calorie fat substitute
KR920007672B1 (ko) * 1990-02-10 1992-09-14 한국식품개발연구원 오메가 지방산 함량이 높고 콜레스테롤 함량이 적은 고기를 생산하기 위한 지방사료첨가제의 제조방법
US5407957A (en) * 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
DK95490D0 (da) * 1990-04-18 1990-04-18 Novo Nordisk As Fremgangsmaade til fremstilling af triglycerid og triglyceridsammensaetning
JPH0423979A (ja) * 1990-05-18 1992-01-28 Kobe Steel Ltd メタン生成細菌およびそれを利用するビタミンｂ↓１↓２の製造法
ES2157898T3 (es) * 1991-01-24 2001-09-01 Martek Corp Aceites microbianos y usos de los mismos.
PH11992043811B1 (en) * 1991-01-24 2002-08-22 Martek Corp Arachidonic acid and methods for the production and use thereof
FR2674865A1 (fr) * 1991-04-02 1992-10-09 Bioprox Ste Angevine Biotechno Procede de preparation d'un concentre liquide d'acide lactique concentre obtenu et son utilisation dans l'industrie alimentaire.
GB9111900D0 (en) * 1991-06-03 1991-07-24 Efamol Holdings Fatty acid compositions
DE69210892T2 (de) * 1991-07-11 1996-10-02 Idemitsu Petrochemical Co Triglyceride enthaltende trockene Zellfragmente und Verfahren zu deren Herstellung
JPH0517796A (ja) * 1991-07-11 1993-01-26 Idemitsu Petrochem Co Ltd トリグリセリドの回収方法
JPH05308979A (ja) * 1992-05-01 1993-11-22 Idemitsu Petrochem Co Ltd トリグリセリド含有乾燥菌体破砕物とその製造法
EP0558112A1 (en) * 1992-02-25 1993-09-01 Unilever N.V. Enzymic diglyceride removal
IL104736A0 (en) * 1992-03-27 1993-06-10 Zeagen Inc Method for producing beta-carotene using a fungal mated culture
JPH05292885A (ja) * 1992-04-22 1993-11-09 Asahi Denka Kogyo Kk チョコレート組成物
JPH06172263A (ja) * 1992-08-14 1994-06-21 Agency Of Ind Science & Technol 高純度アラキドン酸トリグリセリド及びその製造方法
AU683027B2 (en) * 1993-01-27 1997-10-30 Scotia Holdings Plc Triglycerides
JPH06245759A (ja) * 1993-02-19 1994-09-06 Showa Sangyo Co Ltd 油脂生産能力を有する微生物及び油脂の製造法
SI9300303A (en) * 1993-06-08 1994-12-31 Krka Tovarna Zdravil Process for isolation of hypolipemic effective substance
PT707487E (pt) * 1993-06-09 2004-08-31 Martek Biosciences Corp Metodos e composicoes farmaceuticas uteis no tratamento de disturbios neurologicos
JP3506740B2 (ja) * 1993-09-09 2004-03-15 日清オイリオ株式会社 ドコサヘキサエン酸含有藻類の培養方法
AU696261B2 (en) * 1993-09-14 1998-09-03 Loders Croklaan B.V. Healthy spread fats
JP3071088B2 (ja) * 1994-03-02 2000-07-31 昭和産業株式会社 油脂の製造方法及びそのために使用する微生物
JP2566377B2 (ja) * 1994-04-20 1996-12-25 植田製油株式会社 ドコサヘキサエン酸高含有油脂の製造方法
JP3375726B2 (ja) * 1994-05-18 2003-02-10 雪印乳業株式会社 食用油脂および油脂混合物
JP3379220B2 (ja) * 1994-06-15 2003-02-24 三菱化学株式会社 アイスクリーム類用乳化剤及びそれを用いたアイスクリーム類の製造方法
EP0688871A3 (en) * 1994-06-24 1998-07-08 Quest International B.V. Preparation of phytosphingosine derivative
FR2722410B1 (fr) * 1994-07-15 1996-10-04 Grinda Jean Robert Procede de stabilisation des acides gras poly-insatures et utilisation de ces produits stabilises entherapeutique
JP3557653B2 (ja) * 1994-07-25 2004-08-25 不二製油株式会社 ジグリセリド低減方法
CN1217029A (zh) * 1996-03-28 1999-05-19 吉斯特-布罗卡迪斯股份有限公司 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9457108B2 (en) 2002-06-19 2016-10-04 Dsm Ip Assets B.V. Pasteurisation process for microbial cells and microbial oil
CN101837137B (zh) * 2002-06-19 2014-09-24 帝斯曼知识产权资产管理有限公司 用于微生物细胞和微生物油的巴氏消毒方法
CN112280807A (zh) * 2002-06-19 2021-01-29 帝斯曼知识产权资产管理有限公司 包含多不饱和脂肪酸的微生物油的制备
US10493174B2 (en) 2002-06-19 2019-12-03 Dsm Ip Assets B.V. Pasteurisation process for microbial cells and microbial oil
CN101837135B (zh) * 2002-06-19 2014-09-24 帝斯曼知识产权资产管理有限公司 用于微生物细胞和微生物油的巴氏消毒方法
CN109010854A (zh) * 2002-06-19 2018-12-18 帝斯曼知识产权资产管理有限公司 用于微生物细胞和微生物油的巴氏消毒方法
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