CN112400018A - 肝外递送 - Google Patents

肝外递送 Download PDF

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Publication number
CN112400018A
CN112400018A CN201980045507.XA CN201980045507A CN112400018A CN 112400018 A CN112400018 A CN 112400018A CN 201980045507 A CN201980045507 A CN 201980045507A CN 112400018 A CN112400018 A CN 112400018A
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CN
China
Prior art keywords
ome
double
irna agent
positions
stranded irna
Prior art date
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Pending
Application number
CN201980045507.XA
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English (en)
Chinese (zh)
Inventor
J·K·奈尔
M·迈尔
V·贾达夫
S·米尔斯坦
K·布朗
R·G·帕马
K·G·拉杰夫
M·马诺哈兰
A·V·凯尔因
M·贾亚拉曼
K·查理斯
A·卡斯托雷诺
C·S·锡尔
K·非茨杰拉德
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Alnylam Pharmaceuticals Inc
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Alnylam Pharmaceuticals Inc
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Application filed by Alnylam Pharmaceuticals Inc filed Critical Alnylam Pharmaceuticals Inc
Publication of CN112400018A publication Critical patent/CN112400018A/zh
Pending legal-status Critical Current

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