CN101228161B - 适用作蛋白激酶抑制剂的吡咯并吡啶类 - Google Patents

适用作蛋白激酶抑制剂的吡咯并吡啶类 Download PDF

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Publication number
CN101228161B
CN101228161B CN2006800263918A CN200680026391A CN101228161B CN 101228161 B CN101228161 B CN 101228161B CN 2006800263918 A CN2006800263918 A CN 2006800263918A CN 200680026391 A CN200680026391 A CN 200680026391A CN 101228161 B CN101228161 B CN 101228161B
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compound
disease
group
pyrrolo
pyridin
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Expired - Fee Related
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Chinese (zh)
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CN101228161A (zh
Inventor
M·W·里德博尔
M·W·万纳梅克
L·J·法默
王天生
A·C·皮尔斯
G·马蒂内兹-伯塔拉
R·S·贝希尔
G·W·比米斯
王健
F·G·萨里图罗
M·J·阿诺斯特
J·H·科姆
J·格林
M·斯特沃特
C·马赫夫卡
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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CN2006800263918A 2005-05-20 2006-05-22 适用作蛋白激酶抑制剂的吡咯并吡啶类 Expired - Fee Related CN101228161B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68355405P 2005-05-20 2005-05-20
US60/683,554 2005-05-20
PCT/US2006/019711 WO2006127587A1 (en) 2005-05-20 2006-05-22 Pyrrolopyridines useful as inhibitors of protein kinase

Publications (2)

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CN101228161A CN101228161A (zh) 2008-07-23
CN101228161B true CN101228161B (zh) 2012-10-10

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US (1) US8921376B2 (https=)
EP (3) EP2354140A1 (https=)
JP (3) JP2008545660A (https=)
KR (1) KR20080016659A (https=)
CN (1) CN101228161B (https=)
AT (1) ATE540948T1 (https=)
AU (1) AU2006251623A1 (https=)
CA (1) CA2609126A1 (https=)
ES (1) ES2380795T3 (https=)
IL (1) IL187438A0 (https=)
MX (1) MX2007014619A (https=)
NO (1) NO20076502L (https=)
NZ (1) NZ564065A (https=)
RU (2) RU2435769C2 (https=)
WO (1) WO2006127587A1 (https=)
ZA (1) ZA200710379B (https=)

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