CH649299A5 - Acides 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxyliques et leurs derives. - Google Patents
Acides 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxyliques et leurs derives. Download PDFInfo
- Publication number
- CH649299A5 CH649299A5 CH8567/80A CH856780A CH649299A5 CH 649299 A5 CH649299 A5 CH 649299A5 CH 8567/80 A CH8567/80 A CH 8567/80A CH 856780 A CH856780 A CH 856780A CH 649299 A5 CH649299 A5 CH 649299A5
- Authority
- CH
- Switzerland
- Prior art keywords
- oxo
- pyrimidine
- ethyl
- mixture
- mmol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9663179A | 1979-11-23 | 1979-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH649299A5 true CH649299A5 (fr) | 1985-05-15 |
Family
ID=22258306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH8567/80A CH649299A5 (fr) | 1979-11-23 | 1980-11-19 | Acides 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxyliques et leurs derives. |
Country Status (35)
| Country | Link |
|---|---|
| JP (1) | JPS5687586A (ru) |
| KR (1) | KR830004322A (ru) |
| AR (2) | AR228859A1 (ru) |
| AT (1) | AT380883B (ru) |
| AU (1) | AU520995B2 (ru) |
| BE (1) | BE886319A (ru) |
| CA (1) | CA1143731A (ru) |
| CH (1) | CH649299A5 (ru) |
| CS (1) | CS241476B2 (ru) |
| DD (1) | DD154608A5 (ru) |
| DE (2) | DE3043979C2 (ru) |
| DK (1) | DK151811C (ru) |
| EG (1) | EG14929A (ru) |
| ES (1) | ES8203363A1 (ru) |
| FI (1) | FI67706C (ru) |
| FR (1) | FR2470132A1 (ru) |
| GB (1) | GB2063862B (ru) |
| GR (1) | GR72132B (ru) |
| GT (1) | GT198066458A (ru) |
| HU (1) | HU179091B (ru) |
| IE (1) | IE50404B1 (ru) |
| IL (1) | IL61535A (ru) |
| IN (1) | IN154926B (ru) |
| IT (1) | IT1209373B (ru) |
| LU (1) | LU82950A1 (ru) |
| NL (1) | NL182565C (ru) |
| NO (1) | NO803521L (ru) |
| NZ (1) | NZ195596A (ru) |
| PH (1) | PH16666A (ru) |
| PL (1) | PL132354B1 (ru) |
| PT (1) | PT72090B (ru) |
| SE (1) | SE448732B (ru) |
| SU (1) | SU1042620A3 (ru) |
| YU (1) | YU41953B (ru) |
| ZA (1) | ZA807293B (ru) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8300728D0 (en) * | 1983-01-12 | 1983-02-16 | Erba Farmitalia | Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives |
| US4457932A (en) * | 1983-07-22 | 1984-07-03 | Bristol-Myers Company | Anti-ulcer agents |
| GB8422916D0 (en) * | 1984-09-11 | 1984-10-17 | May & Baker Ltd | Compositions of matter |
| JP2690742B2 (ja) * | 1987-03-30 | 1997-12-17 | 第一製薬株式会社 | 複素環アミン誘導体 |
| NZ228447A (en) * | 1988-03-28 | 1990-08-28 | Janssen Pharmaceutica Nv | Cosmetic or pharmaceutical composition possessing serotonin antogonistic activity |
| TWI500623B (zh) * | 2009-10-13 | 2015-09-21 | Torrent Pharmaceuticals Ltd | 新穎稠合噻唑及噁唑嘧啶酮 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1331059A (en) * | 1971-04-19 | 1973-09-19 | Lilly Industries Ltd | Pyrimidotriazinone compounds |
| US4041163A (en) * | 1976-03-29 | 1977-08-09 | Pfizer Inc. | N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents |
| DE2810863A1 (de) * | 1978-03-13 | 1979-09-27 | Boehringer Mannheim Gmbh | 1-oxo-1h-pyrimido eckige klammer auf 6,1-b eckige klammer zu benzthiazol-derivate und verfahren zu ihrer herstellung |
| US4223031A (en) * | 1978-05-05 | 1980-09-16 | Mead Johnson & Company | Azolopyrimidinones |
-
1980
- 1980-09-30 DK DK413180A patent/DK151811C/da not_active IP Right Cessation
- 1980-10-15 IN IN760/DEL/80A patent/IN154926B/en unknown
- 1980-11-17 SU SU803212053A patent/SU1042620A3/ru active
- 1980-11-18 CS CS807820A patent/CS241476B2/cs unknown
- 1980-11-18 HU HU80802755A patent/HU179091B/hu not_active IP Right Cessation
- 1980-11-18 GB GB8036904A patent/GB2063862B/en not_active Expired
- 1980-11-18 AR AR283276A patent/AR228859A1/es active
- 1980-11-19 EG EG723/80A patent/EG14929A/xx active
- 1980-11-19 CH CH8567/80A patent/CH649299A5/fr not_active IP Right Cessation
- 1980-11-20 YU YU2950/80A patent/YU41953B/xx unknown
- 1980-11-20 GR GR63413A patent/GR72132B/el unknown
- 1980-11-20 NZ NZ195596A patent/NZ195596A/en unknown
- 1980-11-21 PH PH24891A patent/PH16666A/en unknown
- 1980-11-21 IT IT8026176A patent/IT1209373B/it active
- 1980-11-21 DE DE3043979A patent/DE3043979C2/de not_active Expired
- 1980-11-21 SE SE8008189A patent/SE448732B/sv not_active IP Right Cessation
- 1980-11-21 DE DE3050491A patent/DE3050491C2/de not_active Expired
- 1980-11-21 JP JP16450280A patent/JPS5687586A/ja active Granted
- 1980-11-21 IE IE2418/80A patent/IE50404B1/en unknown
- 1980-11-21 ES ES497066A patent/ES8203363A1/es not_active Expired
- 1980-11-21 FI FI803628A patent/FI67706C/fi not_active IP Right Cessation
- 1980-11-21 GT GT198066458A patent/GT198066458A/es unknown
- 1980-11-21 PT PT72090A patent/PT72090B/pt not_active IP Right Cessation
- 1980-11-21 CA CA000365258A patent/CA1143731A/en not_active Expired
- 1980-11-21 IL IL61535A patent/IL61535A/xx unknown
- 1980-11-21 ZA ZA00807293A patent/ZA807293B/xx unknown
- 1980-11-21 NL NLAANVRAGE8006362,A patent/NL182565C/xx not_active IP Right Cessation
- 1980-11-21 DD DD80225391A patent/DD154608A5/de not_active IP Right Cessation
- 1980-11-21 AT AT0570780A patent/AT380883B/de not_active IP Right Cessation
- 1980-11-21 FR FR8024822A patent/FR2470132A1/fr active Granted
- 1980-11-21 LU LU82950A patent/LU82950A1/fr unknown
- 1980-11-21 NO NO803521A patent/NO803521L/no unknown
- 1980-11-21 AU AU64595/80A patent/AU520995B2/en not_active Ceased
- 1980-11-22 PL PL1980228008A patent/PL132354B1/pl unknown
- 1980-11-22 KR KR1019800004474A patent/KR830004322A/ko unknown
- 1980-11-24 BE BE0/202915A patent/BE886319A/fr not_active IP Right Cessation
-
1982
- 1982-09-13 AR AR290628A patent/AR231296A1/es active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4376777A (en) | Thiazolidine derivatives use | |
| FR2581065A1 (fr) | Agents cardiotoniques et antithrombogeniques d'imidazoquinoline et leur procede de preparation | |
| JPS6035350B2 (ja) | 右旋性スピローヒダントイン | |
| EP0010029B1 (fr) | Ellipticines substituées en position 1 par une chaîne polyaminée, leur synthèse et médicaments les contenant | |
| CH653025A5 (fr) | Oxazolidine-2,4-diones substituees en position 5 douees d'activite hypoglycemique. | |
| EP0611766A1 (fr) | Dérivés de 2-amido-thiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament | |
| FR2647676A1 (fr) | Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase | |
| CA1097647A (fr) | Procede de preparation de nouvelles imidazoquinoleines et de leurs sels | |
| HU191316B (en) | Process for producing (2-oxo-1,2,3,5-tetrahydro-imidazo /2,1-b/ quinazoline)-oxy-lakyl-amides and pharmacutical compositions containing them | |
| CA1193597A (fr) | Procede de preparation de nouvelles triazoloquinazolones et de leurs sels | |
| CH649299A5 (fr) | Acides 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxyliques et leurs derives. | |
| LU86421A1 (fr) | Derives de piperazine 1,4-disubstitues,composition pharmaceutique les contenant;leur procede d'obtention | |
| CH650254A5 (fr) | Quinolones, leurs procedes de preparation et compositions therapeutiques les contenant. | |
| BE897208A (fr) | Composes de carbostyryle | |
| US4423048A (en) | Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor | |
| US4535081A (en) | Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor | |
| JP2804276B2 (ja) | イミダゾ［２，１―ｂ］チアゾール類 | |
| EP0663903B1 (fr) | Derives de dihydro-1,2 oxo-2 amino-3 quinoxalines, leur preparation et leur application en therapeutique | |
| CH616679A5 (en) | Process for the preparation of N-(5-tetrazolyl)-1-oxo-1H-pyrimido[1,2-a]quinoline-2-carboxamides | |
| GB1569238A (en) | 2,5-dihdro-1,2-thiazino(5,6-b)indol-3-carboxamide-1,1-dioxide derivatives | |
| US4414388A (en) | 1-Oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides | |
| CH629198A5 (fr) | Procede de preparation de nouveaux 2,3-alkylene-bis (oxy)-benzamides substitues. | |
| BE896159A (fr) | 1h-pyrazolo (1,5,-a) pyrimidines substituees et leur preparation | |
| LU81987A1 (fr) | Derives de pyrazolo(1,5-c)quinazoline | |
| WO1979000206A1 (fr) | Nouveaux derives substitues de la 1,3-dihydro imadazo (4, 5-b) pyridin-2-one, procede, application, compositions et intermediaires obtenus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |