CH646154A5 - Imidazol-derivate, verfahren zu ihrer herstellung und solche derivate enthaltende arzneimittel. - Google Patents

Imidazol-derivate, verfahren zu ihrer herstellung und solche derivate enthaltende arzneimittel. Download PDF

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Publication number
CH646154A5
CH646154A5 CH42080A CH42080A CH646154A5 CH 646154 A5 CH646154 A5 CH 646154A5 CH 42080 A CH42080 A CH 42080A CH 42080 A CH42080 A CH 42080A CH 646154 A5 CH646154 A5 CH 646154A5
Authority
CH
Switzerland
Prior art keywords
imidazolylmethyl
formula
compound
compounds
acid
Prior art date
Application number
CH42080A
Other languages
German (de)
English (en)
Inventor
Peter Edward Cross
Roger Peter Dickinson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CH646154A5 publication Critical patent/CH646154A5/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH42080A 1979-01-19 1980-01-18 Imidazol-derivate, verfahren zu ihrer herstellung und solche derivate enthaltende arzneimittel. CH646154A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7902114 1979-01-19

Publications (1)

Publication Number Publication Date
CH646154A5 true CH646154A5 (de) 1984-11-15

Family

ID=10502633

Family Applications (1)

Application Number Title Priority Date Filing Date
CH42080A CH646154A5 (de) 1979-01-19 1980-01-18 Imidazol-derivate, verfahren zu ihrer herstellung und solche derivate enthaltende arzneimittel.

Country Status (31)

Country Link
US (2) US4555516A (US07345094-20080318-C00003.png)
JP (1) JPS5946504B2 (US07345094-20080318-C00003.png)
KR (1) KR840001707B1 (US07345094-20080318-C00003.png)
AR (1) AR222204A1 (US07345094-20080318-C00003.png)
AT (1) AT373880B (US07345094-20080318-C00003.png)
AU (1) AU517241B2 (US07345094-20080318-C00003.png)
BE (1) BE881245A (US07345094-20080318-C00003.png)
CA (1) CA1137481A (US07345094-20080318-C00003.png)
CH (1) CH646154A5 (US07345094-20080318-C00003.png)
DD (1) DD148773A5 (US07345094-20080318-C00003.png)
DE (1) DE3001762A1 (US07345094-20080318-C00003.png)
DK (1) DK531479A (US07345094-20080318-C00003.png)
ES (1) ES8101557A1 (US07345094-20080318-C00003.png)
FI (1) FI800143A (US07345094-20080318-C00003.png)
FR (1) FR2446828A1 (US07345094-20080318-C00003.png)
GR (1) GR71914B (US07345094-20080318-C00003.png)
HU (1) HU184227B (US07345094-20080318-C00003.png)
IE (1) IE49364B1 (US07345094-20080318-C00003.png)
IL (1) IL59150A (US07345094-20080318-C00003.png)
IT (1) IT1140523B (US07345094-20080318-C00003.png)
LU (1) LU82087A1 (US07345094-20080318-C00003.png)
NL (1) NL8000333A (US07345094-20080318-C00003.png)
NO (1) NO800131L (US07345094-20080318-C00003.png)
NZ (1) NZ192640A (US07345094-20080318-C00003.png)
PH (1) PH14910A (US07345094-20080318-C00003.png)
PL (1) PL123985B1 (US07345094-20080318-C00003.png)
PT (1) PT70707A (US07345094-20080318-C00003.png)
SE (1) SE8000435L (US07345094-20080318-C00003.png)
SU (1) SU906374A3 (US07345094-20080318-C00003.png)
YU (1) YU11380A (US07345094-20080318-C00003.png)
ZA (1) ZA80298B (US07345094-20080318-C00003.png)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
DK157860C (da) * 1979-06-07 1990-07-30 Shionogi & Co Analogifremgangsmaade til fremstilling af benzylimidazolderivater samt farmaceutisk acceptable syreadditionssalte deraf
JPS56113766A (en) * 1980-02-12 1981-09-07 Teijin Ltd Novel 1-substituted imidazole derivative and its preparation
JPS57169452A (en) * 1981-04-14 1982-10-19 Teikoku Hormone Mfg Co Ltd Novel phenoxyalkylamide derivative
DE3235589A1 (de) * 1982-09-25 1984-03-29 Hoechst Ag, 6230 Frankfurt Benzylether von phenol-mannich-basen, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen, zwischenprodukte und verfahren zu deren herstellung
DE3424944A1 (de) * 1984-07-06 1986-02-06 Hoechst Ag, 6230 Frankfurt Neue imidazolyverbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
US4937250A (en) * 1988-03-07 1990-06-26 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
CA1338238C (en) 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
US5210079A (en) * 1988-01-07 1993-05-11 E. I. Du Pont De Nemours And Company Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
US5354867A (en) * 1988-12-06 1994-10-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
SG50669A1 (en) * 1989-06-30 1998-07-20 Du Pont Fused-ring aryl subtituted imidazoles
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5616599A (en) * 1991-02-21 1997-04-01 Sankyo Company, Limited Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
US5332820A (en) * 1991-05-20 1994-07-26 E. I. Du Pont De Nemours And Company Dibenzobicyclo(2.2.2) octane angiotensin II antagonists
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
US5612360A (en) * 1992-06-03 1997-03-18 Eli Lilly And Company Angiotensin II antagonists
JP3501484B2 (ja) * 1992-12-17 2004-03-02 三共株式会社 ビフェニル誘導体
EP0757988A4 (en) * 1994-04-27 2000-07-26 Nippon Soda Co IMIDAZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME
TW434240B (en) * 1995-06-20 2001-05-16 Zeneca Ltd Aromatic compounds, preparation thereof and pharmaceutical composition comprising same
ATE252563T1 (de) * 1995-12-27 2003-11-15 Mitsubishi Pharma Corp Vorsorge-/heilmittel fur die komplikationen von diabetes
JP4056589B2 (ja) * 1996-07-19 2008-03-05 武田薬品工業株式会社 複素環化合物、その製造法および用途
IT1295405B1 (it) 1997-09-30 1999-05-12 Merck Sharp & Dohme Italia S P Uso di un antagonista recettoriale di angiotensina ii per la preparazione di farmaci per aumentare il tasso di sopravvivenza di
KR100423890B1 (ko) * 2000-10-19 2004-03-24 씨제이 주식회사 세팔로스포린 유도체의 새로운 제조방법
TW200505913A (en) * 2003-03-28 2005-02-16 Hoffmann La Roche Novel oxazole derivatives, their manufacture and use as pharmaceutical agents
CN117624052B (zh) * 2024-01-26 2024-04-12 四川益能康生环保科技有限公司 一种用于捕集二氧化碳的离子液体及其制备方法

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Publication number Priority date Publication date Assignee Title
CH271776A (de) * 1949-01-06 1950-11-15 Ag J R Geigy Verfahren zur Herstellung eines basischen Äthers eines ortho-substituierten Phenols.
US3498999A (en) * 1966-04-20 1970-03-03 Bristol Myers Co 1-phenoxy and substituted phenoxy-3-(5-tetrazolyl) propanes
IE40911B1 (en) * 1974-04-11 1979-09-12 Schering Ag Imidazole derivatives and process for their manufacture
DE2461406C2 (de) * 1974-12-24 1984-06-14 Bayer Ag, 5090 Leverkusen Azolyl-(1)-methane und deren Salze, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
US4085209A (en) * 1975-02-05 1978-04-18 Rohm And Haas Company Preparation and safening effect of 1-substituted imidazole metal salt complexes
DE2646143A1 (de) * 1976-10-13 1978-04-20 Bayer Ag 4,5-dichlor-imidazol-1-carbonsaeure- arylester, verfahren zu ihrer herstellung sowie ihre verwendung als pflanzenschutzmittel
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体

Also Published As

Publication number Publication date
IE800102L (en) 1980-07-19
IT8019276A0 (it) 1980-01-17
JPS55100368A (en) 1980-07-31
PT70707A (en) 1980-02-01
IL59150A0 (en) 1980-05-30
KR840001707B1 (ko) 1984-10-16
AU5474380A (en) 1980-07-24
DD148773A5 (de) 1981-06-10
IL59150A (en) 1983-11-30
US4555516A (en) 1985-11-26
HU184227B (en) 1984-07-30
AR222204A1 (es) 1981-04-30
PL123985B1 (en) 1982-12-31
LU82087A1 (fr) 1980-04-23
FR2446828B1 (US07345094-20080318-C00003.png) 1983-05-13
FR2446828A1 (fr) 1980-08-14
SE8000435L (sv) 1980-07-20
DE3001762A1 (de) 1980-07-24
ATA24680A (de) 1983-07-15
IE49364B1 (en) 1985-09-18
ZA80298B (en) 1981-08-26
AT373880B (de) 1984-02-27
NZ192640A (en) 1984-07-31
PL221461A1 (US07345094-20080318-C00003.png) 1980-09-22
US4448781A (en) 1984-05-15
PH14910A (en) 1982-01-29
BE881245A (fr) 1980-07-18
DK531479A (da) 1980-07-20
CA1137481A (en) 1982-12-14
YU11380A (en) 1983-04-30
FI800143A (fi) 1980-07-20
NL8000333A (nl) 1980-07-22
NO800131L (no) 1980-07-21
GR71914B (US07345094-20080318-C00003.png) 1983-08-16
ES487843A0 (es) 1980-12-16
IT1140523B (it) 1986-10-01
KR830001905A (ko) 1983-05-19
JPS5946504B2 (ja) 1984-11-13
AU517241B2 (en) 1981-07-16
ES8101557A1 (es) 1980-12-16
SU906374A3 (ru) 1982-02-15

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