CH644105A5 - Acides et esters 4-amino-3-quinoleinecarboxyliques, utiles notamment comme agent antisecretoires et anti-ulcere. - Google Patents

Acides et esters 4-amino-3-quinoleinecarboxyliques, utiles notamment comme agent antisecretoires et anti-ulcere. Download PDF

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Publication number
CH644105A5
CH644105A5 CH234080A CH234080A CH644105A5 CH 644105 A5 CH644105 A5 CH 644105A5 CH 234080 A CH234080 A CH 234080A CH 234080 A CH234080 A CH 234080A CH 644105 A5 CH644105 A5 CH 644105A5
Authority
CH
Switzerland
Prior art keywords
amino
quinolinecarboxylate
ethyl
methoxy
hydrochloride
Prior art date
Application number
CH234080A
Other languages
English (en)
French (fr)
Inventor
Harry Randall Jun Munson
Reevis Stancil Alphin
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of CH644105A5 publication Critical patent/CH644105A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH234080A 1979-03-26 1980-03-25 Acides et esters 4-amino-3-quinoleinecarboxyliques, utiles notamment comme agent antisecretoires et anti-ulcere. CH644105A5 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds

Publications (1)

Publication Number Publication Date
CH644105A5 true CH644105A5 (fr) 1984-07-13

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
CH234080A CH644105A5 (fr) 1979-03-26 1980-03-25 Acides et esters 4-amino-3-quinoleinecarboxyliques, utiles notamment comme agent antisecretoires et anti-ulcere.

Country Status (31)

Country Link
US (1) US4343804A (enExample)
JP (1) JPH02117663A (enExample)
AR (1) AR230268A1 (enExample)
AT (1) AT372373B (enExample)
AU (1) AU528388B2 (enExample)
BR (1) BR8001779A (enExample)
CA (1) CA1147338A (enExample)
CH (1) CH644105A5 (enExample)
DE (1) DE3011490A1 (enExample)
DK (1) DK156056C (enExample)
EG (1) EG15009A (enExample)
ES (1) ES8103048A1 (enExample)
FI (1) FI77452C (enExample)
FR (1) FR2452485B1 (enExample)
GB (1) GB2047244B (enExample)
GR (1) GR68006B (enExample)
HK (1) HK67983A (enExample)
IE (1) IE49577B1 (enExample)
IL (1) IL59628A (enExample)
IN (1) IN151446B (enExample)
IT (1) IT1133079B (enExample)
MX (1) MX6264E (enExample)
NL (1) NL8001752A (enExample)
NO (1) NO153927C (enExample)
NZ (1) NZ193252A (enExample)
PH (1) PH16416A (enExample)
PL (1) PL125030B1 (enExample)
PT (1) PT71008B (enExample)
SE (1) SE435837B (enExample)
SG (1) SG33683G (enExample)
YU (1) YU41702B (enExample)

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GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
WO1995004720A2 (en) * 1993-08-10 1995-02-16 Black James Foundation Gastrin and cck receptor ligands
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
KR100736502B1 (ko) 1998-09-29 2007-07-06 와이어쓰 홀딩스 코포레이션 단백질 티로신 키나제 억제제로서 치환된 3-시아노퀴놀린
KR100641802B1 (ko) * 1999-12-28 2006-11-02 에자이 가부시키가이샤 술폰아미드 함유 복소환 화합물
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
BRPI0406761A (pt) 2003-01-14 2005-12-20 Arena Pharm Inc Derivados de arila e heteroarila 1,2,3-trissubstituìdos como moduladores do metabolismo e a profilaxia e tratamento de distúrbios relacionados a estes tais como diabetes e hiper-glicemia
RS52908B (sr) 2003-03-10 2014-02-28 Takeda Gmbh Novi postupak za dobijanje roflumilasta
AR045697A1 (es) * 2003-07-14 2005-11-09 Arena Pharm Inc Aril y heteroaril derivados fusionados como moduladores del metabolismo y la prevencion y tratamiento de trastornos relacionados con el mismo
CA2601250C (en) * 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
EP4148045A1 (en) 2010-01-27 2023-03-15 Arena Pharmaceuticals, Inc. Intermediate compounds for the preparation of (r)-2-(7-(4-cyclopentyl-3- (trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b] indol-3-yl)acetic acid and salts thereof
SG188548A1 (en) 2010-09-22 2013-04-30 Arena Pharm Inc Modulators of the gpr119 receptor and the treatment of disorders related thereto
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
CA3002551A1 (en) 2015-06-22 2016-12-29 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(com pound 1)for use in s1p1 receptor-associated disorders
US10889573B2 (en) 2016-11-11 2021-01-12 Bayer Animal Health Gmbh Anthelmintic quinoline-3-carboxamide derivatives
CA3053418A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
WO2019084271A1 (en) * 2017-10-25 2019-05-02 Children's Medical Center Corporation PAPD5 INHIBITORS AND METHODS OF USE
EP3790874B1 (en) 2018-05-09 2023-03-15 Bayer Animal Health GmbH Anthelmintic quinoline derivatives
CA3102136A1 (en) 2018-06-06 2019-12-12 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor
CN113993848A (zh) 2019-04-24 2022-01-28 儿童医学中心公司 Papd5抑制剂及其使用方法

Family Cites Families (2)

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Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (enExample) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
PH16416A (en) 1983-09-29
FR2452485A1 (fr) 1980-10-24
IL59628A0 (en) 1980-06-30
US4343804A (en) 1982-08-10
FI77452B (fi) 1988-11-30
ES489887A0 (es) 1981-02-16
MX6264E (es) 1985-02-19
DK156056C (da) 1989-11-06
IN151446B (enExample) 1983-04-23
PL125030B1 (en) 1983-03-31
IE49577B1 (en) 1985-10-30
EG15009A (en) 1985-03-31
FI77452C (fi) 1989-03-10
IT8067465A0 (it) 1980-03-26
PT71008B (en) 1981-06-25
SG33683G (en) 1985-03-29
CA1147338A (en) 1983-05-31
IT1133079B (it) 1986-07-09
SE435837B (sv) 1984-10-22
NO800858L (no) 1980-09-29
GR68006B (enExample) 1981-10-26
YU41702B (en) 1987-12-31
AU528388B2 (en) 1983-04-28
NO153927C (no) 1986-06-18
DE3011490C2 (enExample) 1988-12-22
PT71008A (en) 1980-04-01
AR230268A1 (es) 1984-03-01
DK128380A (da) 1980-09-27
SE8002292L (sv) 1980-09-27
PL222993A1 (enExample) 1981-01-30
JPH02117663A (ja) 1990-05-02
AT372373B (de) 1983-09-26
DK156056B (da) 1989-06-19
YU84480A (en) 1983-10-31
GB2047244A (en) 1980-11-26
HK67983A (en) 1983-12-23
ATA156480A (de) 1983-02-15
FI800910A7 (fi) 1980-09-27
DE3011490A1 (de) 1981-03-12
AU5684880A (en) 1980-10-02
BR8001779A (pt) 1980-11-18
GB2047244B (en) 1983-02-23
IE800605L (en) 1980-09-26
NO153927B (no) 1986-03-10
ES8103048A1 (es) 1981-02-16
IL59628A (en) 1983-06-15
FR2452485B1 (fr) 1986-09-12
NZ193252A (en) 1984-04-27
NL8001752A (nl) 1980-09-30

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