HK67983A - 8-substituted-4-amino-3-quinaline-carboxylic acids and esters-antisecretary,anti-ulcer compounds - Google Patents

8-substituted-4-amino-3-quinaline-carboxylic acids and esters-antisecretary,anti-ulcer compounds

Info

Publication number
HK67983A
HK67983A HK679/83A HK67983A HK67983A HK 67983 A HK67983 A HK 67983A HK 679/83 A HK679/83 A HK 679/83A HK 67983 A HK67983 A HK 67983A HK 67983 A HK67983 A HK 67983A
Authority
HK
Hong Kong
Prior art keywords
antisecretary
quinaline
esters
amino
substituted
Prior art date
Application number
HK679/83A
Other languages
English (en)
Inventor
Harry Randall Munson
Reevis Stancil Alphin
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of HK67983A publication Critical patent/HK67983A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK679/83A 1979-03-26 1983-12-15 8-substituted-4-amino-3-quinaline-carboxylic acids and esters-antisecretary,anti-ulcer compounds HK67983A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds

Publications (1)

Publication Number Publication Date
HK67983A true HK67983A (en) 1983-12-23

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
HK679/83A HK67983A (en) 1979-03-26 1983-12-15 8-substituted-4-amino-3-quinaline-carboxylic acids and esters-antisecretary,anti-ulcer compounds

Country Status (31)

Country Link
US (1) US4343804A (xx)
JP (1) JPH02117663A (xx)
AR (1) AR230268A1 (xx)
AT (1) AT372373B (xx)
AU (1) AU528388B2 (xx)
BR (1) BR8001779A (xx)
CA (1) CA1147338A (xx)
CH (1) CH644105A5 (xx)
DE (1) DE3011490A1 (xx)
DK (1) DK156056C (xx)
EG (1) EG15009A (xx)
ES (1) ES489887A0 (xx)
FI (1) FI77452C (xx)
FR (1) FR2452485B1 (xx)
GB (1) GB2047244B (xx)
GR (1) GR68006B (xx)
HK (1) HK67983A (xx)
IE (1) IE49577B1 (xx)
IL (1) IL59628A (xx)
IN (1) IN151446B (xx)
IT (1) IT1133079B (xx)
MX (1) MX6264E (xx)
NL (1) NL8001752A (xx)
NO (1) NO153927C (xx)
NZ (1) NZ193252A (xx)
PH (1) PH16416A (xx)
PL (1) PL125030B1 (xx)
PT (1) PT71008B (xx)
SE (1) SE435837B (xx)
SG (1) SG33683G (xx)
YU (1) YU41702B (xx)

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GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
CA2167154A1 (en) * 1993-08-10 1995-02-16 Sarkis Barret Kalindjian Gastrin and cck receptor ligands
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
SI2253620T1 (sl) 1998-09-29 2014-06-30 Wyeth Holdings Llc Substituirani 3-cianokinolini kot inhibitorji protein tirozin-kinaz
WO2001047891A1 (fr) * 1999-12-28 2001-07-05 Eisai Co., Ltd. Composes heterocylciques contenant des groupes de sulfamide
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
NZ540612A (en) 2003-01-14 2008-02-29 Arena Pharm Inc 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
CA2503290C (en) 2003-03-10 2012-12-04 Altana Pharma Ag Novel process for the preparation of roflumilast
AU2004257267B2 (en) * 2003-07-14 2009-12-03 Arena Pharmaceuticals,Inc Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
CA2601250C (en) * 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
WO2011094008A1 (en) 2010-01-27 2011-08-04 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
EP2619198A1 (en) 2010-09-22 2013-07-31 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
EP4445956A2 (en) 2015-01-06 2024-10-16 Arena Pharmaceuticals, Inc. Compound for use in treating conditions related to the s1p1 receptor
WO2016209809A1 (en) 2015-06-22 2016-12-29 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders
ES2884073T3 (es) 2016-11-11 2021-12-10 Bayer Animal Health Gmbh Nuevos derivados antihelmínticos de quinolina-3-carboxamida
WO2018151873A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
US20210177827A1 (en) * 2017-10-25 2021-06-17 Children`S Medical Center Corporation Papd5 inhibitors and methods of use thereof
BR112020022619A2 (pt) 2018-05-09 2021-02-02 Bayer Animal Health Gmbh novos derivados de quinolina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (xx) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
IE49577B1 (en) 1985-10-30
DK156056B (da) 1989-06-19
FR2452485A1 (fr) 1980-10-24
PT71008B (en) 1981-06-25
YU84480A (en) 1983-10-31
ES8103048A1 (es) 1981-02-16
FR2452485B1 (fr) 1986-09-12
ES489887A0 (es) 1981-02-16
IE800605L (en) 1980-09-26
IT8067465A0 (it) 1980-03-26
YU41702B (en) 1987-12-31
SG33683G (en) 1985-03-29
JPH02117663A (ja) 1990-05-02
NZ193252A (en) 1984-04-27
FI77452B (fi) 1988-11-30
GB2047244A (en) 1980-11-26
DE3011490A1 (de) 1981-03-12
AU5684880A (en) 1980-10-02
ATA156480A (de) 1983-02-15
GR68006B (xx) 1981-10-26
DK156056C (da) 1989-11-06
NO800858L (no) 1980-09-29
SE8002292L (sv) 1980-09-27
AT372373B (de) 1983-09-26
BR8001779A (pt) 1980-11-18
IN151446B (xx) 1983-04-23
PL222993A1 (xx) 1981-01-30
FI800910A (fi) 1980-09-27
PH16416A (en) 1983-09-29
PL125030B1 (en) 1983-03-31
CH644105A5 (fr) 1984-07-13
MX6264E (es) 1985-02-19
IT1133079B (it) 1986-07-09
GB2047244B (en) 1983-02-23
US4343804A (en) 1982-08-10
AU528388B2 (en) 1983-04-28
NO153927C (no) 1986-06-18
DE3011490C2 (xx) 1988-12-22
IL59628A (en) 1983-06-15
FI77452C (fi) 1989-03-10
NL8001752A (nl) 1980-09-30
SE435837B (sv) 1984-10-22
PT71008A (en) 1980-04-01
IL59628A0 (en) 1980-06-30
CA1147338A (en) 1983-05-31
AR230268A1 (es) 1984-03-01
DK128380A (da) 1980-09-27
EG15009A (en) 1985-03-31
NO153927B (no) 1986-03-10

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