HK67983A - 8-substituted-4-amino-3-quinaline-carboxylic acids and esters-antisecretary,anti-ulcer compounds - Google Patents

8-substituted-4-amino-3-quinaline-carboxylic acids and esters-antisecretary,anti-ulcer compounds

Info

Publication number
HK67983A
HK67983A HK679/83A HK67983A HK67983A HK 67983 A HK67983 A HK 67983A HK 679/83 A HK679/83 A HK 679/83A HK 67983 A HK67983 A HK 67983A HK 67983 A HK67983 A HK 67983A
Authority
HK
Hong Kong
Prior art keywords
antisecretary
quinaline
esters
amino
substituted
Prior art date
Application number
HK679/83A
Other languages
English (en)
Inventor
Harry Randall Munson
Reevis Stancil Alphin
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of HK67983A publication Critical patent/HK67983A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK679/83A 1979-03-26 1983-12-15 8-substituted-4-amino-3-quinaline-carboxylic acids and esters-antisecretary,anti-ulcer compounds HK67983A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds

Publications (1)

Publication Number Publication Date
HK67983A true HK67983A (en) 1983-12-23

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
HK679/83A HK67983A (en) 1979-03-26 1983-12-15 8-substituted-4-amino-3-quinaline-carboxylic acids and esters-antisecretary,anti-ulcer compounds

Country Status (31)

Country Link
US (1) US4343804A (xx)
JP (1) JPH02117663A (xx)
AR (1) AR230268A1 (xx)
AT (1) AT372373B (xx)
AU (1) AU528388B2 (xx)
BR (1) BR8001779A (xx)
CA (1) CA1147338A (xx)
CH (1) CH644105A5 (xx)
DE (1) DE3011490A1 (xx)
DK (1) DK156056C (xx)
EG (1) EG15009A (xx)
ES (1) ES489887A0 (xx)
FI (1) FI77452C (xx)
FR (1) FR2452485B1 (xx)
GB (1) GB2047244B (xx)
GR (1) GR68006B (xx)
HK (1) HK67983A (xx)
IE (1) IE49577B1 (xx)
IL (1) IL59628A (xx)
IN (1) IN151446B (xx)
IT (1) IT1133079B (xx)
MX (1) MX6264E (xx)
NL (1) NL8001752A (xx)
NO (1) NO153927C (xx)
NZ (1) NZ193252A (xx)
PH (1) PH16416A (xx)
PL (1) PL125030B1 (xx)
PT (1) PT71008B (xx)
SE (1) SE435837B (xx)
SG (1) SG33683G (xx)
YU (1) YU41702B (xx)

Families Citing this family (42)

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GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
CA2167154A1 (en) * 1993-08-10 1995-02-16 Sarkis Barret Kalindjian Gastrin and cck receptor ligands
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
BR9914164A (pt) 1998-09-29 2001-06-26 American Cyanamid Co Composto, método para o tratamento, inibição do crescimento de, ou erradiacação de um neoplasma, e de doença de rim policìstico, em um mamìfero em necessidade do mesmo, composição farmacêutica, e, processo para preparar um composto
MXPA02006474A (es) * 1999-12-28 2002-11-29 Eisai Co Ltd Compuestos heterociclicos que contienen sulfonamida.
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
US8293751B2 (en) 2003-01-14 2012-10-23 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
ME00524B (me) 2003-03-10 2011-10-10 Astrazeneca Ab Novi postupak za dobijanje roflumilasta
WO2005007658A2 (en) * 2003-07-14 2005-01-27 Arena Pharmaceuticals, Inc. Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
CA2601250C (en) * 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
EP3378854B1 (en) 2010-01-27 2022-12-21 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
BR112013008100A2 (pt) 2010-09-22 2016-08-09 Arena Pharm Inc "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles."
CN116850181A (zh) 2015-01-06 2023-10-10 艾尼纳制药公司 治疗与s1p1受体有关的病症的方法
MX2017016530A (es) 2015-06-22 2018-03-12 Arena Pharm Inc Sal cristalina de l-arginina del acido (r)-2-(7-(4-ciclopentil-3-( trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclopenta[b]indol-3- il)acetico (compuesto1) para ser utilizada en transtornos asociados con el receptor de esfingosina-1-fosfato 1 (s1p1).
ES2884073T3 (es) * 2016-11-11 2021-12-10 Bayer Animal Health Gmbh Nuevos derivados antihelmínticos de quinolina-3-carboxamida
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
EP3700527A4 (en) * 2017-10-25 2021-03-10 Children's Medical Center Corporation PAPD5 INHIBITORS AND THEIR METHODS OF USE
WO2019215182A1 (en) 2018-05-09 2019-11-14 Bayer Animal Health Gmbh New quinoline derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (xx) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
IE800605L (en) 1980-09-26
NO153927C (no) 1986-06-18
CA1147338A (en) 1983-05-31
SE8002292L (sv) 1980-09-27
IT1133079B (it) 1986-07-09
EG15009A (en) 1985-03-31
GB2047244B (en) 1983-02-23
PH16416A (en) 1983-09-29
SG33683G (en) 1985-03-29
DK156056C (da) 1989-11-06
SE435837B (sv) 1984-10-22
PL222993A1 (xx) 1981-01-30
PT71008A (en) 1980-04-01
GR68006B (xx) 1981-10-26
IT8067465A0 (it) 1980-03-26
FI77452B (fi) 1988-11-30
ATA156480A (de) 1983-02-15
PT71008B (en) 1981-06-25
AT372373B (de) 1983-09-26
IE49577B1 (en) 1985-10-30
DE3011490A1 (de) 1981-03-12
MX6264E (es) 1985-02-19
BR8001779A (pt) 1980-11-18
DE3011490C2 (xx) 1988-12-22
NO800858L (no) 1980-09-29
CH644105A5 (fr) 1984-07-13
AU5684880A (en) 1980-10-02
JPH02117663A (ja) 1990-05-02
FI800910A (fi) 1980-09-27
DK128380A (da) 1980-09-27
AU528388B2 (en) 1983-04-28
US4343804A (en) 1982-08-10
YU84480A (en) 1983-10-31
NL8001752A (nl) 1980-09-30
NZ193252A (en) 1984-04-27
FR2452485A1 (fr) 1980-10-24
IN151446B (xx) 1983-04-23
FI77452C (fi) 1989-03-10
PL125030B1 (en) 1983-03-31
NO153927B (no) 1986-03-10
AR230268A1 (es) 1984-03-01
ES8103048A1 (es) 1981-02-16
GB2047244A (en) 1980-11-26
YU41702B (en) 1987-12-31
IL59628A (en) 1983-06-15
FR2452485B1 (fr) 1986-09-12
IL59628A0 (en) 1980-06-30
ES489887A0 (es) 1981-02-16
DK156056B (da) 1989-06-19

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