DK128380A - 4-amino-3-quinolin-carboxylsyrer og syreestere deres fremstilling og anvendelse - Google Patents

4-amino-3-quinolin-carboxylsyrer og syreestere deres fremstilling og anvendelse

Info

Publication number
DK128380A
DK128380A DK128380A DK128380A DK128380A DK 128380 A DK128380 A DK 128380A DK 128380 A DK128380 A DK 128380A DK 128380 A DK128380 A DK 128380A DK 128380 A DK128380 A DK 128380A
Authority
DK
Denmark
Prior art keywords
amino
preparation
acid esters
carboxylic acids
quinoline carboxylic
Prior art date
Application number
DK128380A
Other languages
English (en)
Other versions
DK156056B (da
DK156056C (da
Inventor
H R Munson
R S Alphin
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of DK128380A publication Critical patent/DK128380A/da
Publication of DK156056B publication Critical patent/DK156056B/da
Application granted granted Critical
Publication of DK156056C publication Critical patent/DK156056C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK128380A 1979-03-26 1980-03-25 Analogifremgangsmaade til fremstilling af 4-amino-3-quinolin-carboxylsyrederivater DK156056C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US2398179 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
US12715380 1980-03-04

Publications (3)

Publication Number Publication Date
DK128380A true DK128380A (da) 1980-09-27
DK156056B DK156056B (da) 1989-06-19
DK156056C DK156056C (da) 1989-11-06

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
DK128380A DK156056C (da) 1979-03-26 1980-03-25 Analogifremgangsmaade til fremstilling af 4-amino-3-quinolin-carboxylsyrederivater

Country Status (31)

Country Link
US (1) US4343804A (da)
JP (1) JPH02117663A (da)
AR (1) AR230268A1 (da)
AT (1) AT372373B (da)
AU (1) AU528388B2 (da)
BR (1) BR8001779A (da)
CA (1) CA1147338A (da)
CH (1) CH644105A5 (da)
DE (1) DE3011490A1 (da)
DK (1) DK156056C (da)
EG (1) EG15009A (da)
ES (1) ES489887A0 (da)
FI (1) FI77452C (da)
FR (1) FR2452485B1 (da)
GB (1) GB2047244B (da)
GR (1) GR68006B (da)
HK (1) HK67983A (da)
IE (1) IE49577B1 (da)
IL (1) IL59628A (da)
IN (1) IN151446B (da)
IT (1) IT1133079B (da)
MX (1) MX6264E (da)
NL (1) NL8001752A (da)
NO (1) NO153927C (da)
NZ (1) NZ193252A (da)
PH (1) PH16416A (da)
PL (1) PL125030B1 (da)
PT (1) PT71008B (da)
SE (1) SE435837B (da)
SG (1) SG33683G (da)
YU (1) YU41702B (da)

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GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
ATE197146T1 (de) * 1993-08-10 2000-11-15 Black James Foundation Gastrin-und cck-rezeptorligande
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
JP4537582B2 (ja) 1998-09-29 2010-09-01 アメリカン・サイアナミド・カンパニー プロテインチロシンキナーゼインヒビターとしての置換３−シアノキノリン
ATE305302T1 (de) * 1999-12-28 2005-10-15 Eisai Co Ltd Heterozyklische verbindungen mit sulfonamid- gruppen
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ATE374766T1 (de) 2003-01-14 2007-10-15 Arena Pharm Inc 1,2,3-trisubstituierte aryl- und heteroarylderivate als modulatoren des metabolismus zur vorbeugung und behandlung von metabolismus-bedingten krankheiten wie diabetes oder hyperglykämie
US7470791B2 (en) 2003-03-10 2008-12-30 Nycomed Gmbh Process for the preparation of roflumilast
AU2004257267B2 (en) * 2003-07-14 2009-12-03 Arena Pharmaceuticals,Inc Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ， インコーポレイテッド （Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸およびその塩の調製のためのプロセス
CA2812061A1 (en) 2010-09-22 2012-03-29 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
CN107405332A (zh) 2015-01-06 2017-11-28 艾尼纳制药公司 治疗与s1p1受体有关的病症的方法
CA3002551A1 (en) 2015-06-22 2016-12-29 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(com pound 1)for use in s1p1 receptor-associated disorders
CN109890793B (zh) 2016-11-11 2022-11-18 拜耳动物保健有限责任公司 新的抗蠕虫药喹啉-3-甲酰胺衍生物
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
US20210177827A1 (en) * 2017-10-25 2021-06-17 Children`S Medical Center Corporation Papd5 inhibitors and methods of use thereof
PT3790874T (pt) 2018-05-09 2023-05-31 Bayer Animal Health Gmbh Derivados de quinolina antelmínticos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (da) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
DE3011490A1 (de) 1981-03-12
GB2047244A (en) 1980-11-26
CA1147338A (en) 1983-05-31
SG33683G (en) 1985-03-29
CH644105A5 (fr) 1984-07-13
GR68006B (da) 1981-10-26
PT71008B (en) 1981-06-25
NO153927C (no) 1986-06-18
FI77452B (fi) 1988-11-30
DE3011490C2 (da) 1988-12-22
PL222993A1 (da) 1981-01-30
US4343804A (en) 1982-08-10
FI77452C (fi) 1989-03-10
NZ193252A (en) 1984-04-27
YU84480A (en) 1983-10-31
BR8001779A (pt) 1980-11-18
NO800858L (no) 1980-09-29
EG15009A (en) 1985-03-31
NL8001752A (nl) 1980-09-30
YU41702B (en) 1987-12-31
FR2452485B1 (fr) 1986-09-12
DK156056B (da) 1989-06-19
FI800910A (fi) 1980-09-27
FR2452485A1 (fr) 1980-10-24
IN151446B (da) 1983-04-23
IL59628A (en) 1983-06-15
IE800605L (en) 1980-09-26
IT1133079B (it) 1986-07-09
AT372373B (de) 1983-09-26
ES8103048A1 (es) 1981-02-16
HK67983A (en) 1983-12-23
IL59628A0 (en) 1980-06-30
IE49577B1 (en) 1985-10-30
NO153927B (no) 1986-03-10
AR230268A1 (es) 1984-03-01
AU528388B2 (en) 1983-04-28
MX6264E (es) 1985-02-19
SE435837B (sv) 1984-10-22
PH16416A (en) 1983-09-29
ATA156480A (de) 1983-02-15
PT71008A (en) 1980-04-01
GB2047244B (en) 1983-02-23
IT8067465A0 (it) 1980-03-26
SE8002292L (sv) 1980-09-27
DK156056C (da) 1989-11-06
AU5684880A (en) 1980-10-02
JPH02117663A (ja) 1990-05-02
PL125030B1 (en) 1983-03-31
ES489887A0 (es) 1981-02-16

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Legal Events

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PBP Patent lapsed