FR2452485B1 - Nouveaux acides et esters 4-amino-3-quinoleinecarboxyliques, utiles notamment comme agents antisecretoires et anti-ulcere - Google Patents
Nouveaux acides et esters 4-amino-3-quinoleinecarboxyliques, utiles notamment comme agents antisecretoires et anti-ulcereInfo
- Publication number
- FR2452485B1 FR2452485B1 FR8006516A FR8006516A FR2452485B1 FR 2452485 B1 FR2452485 B1 FR 2452485B1 FR 8006516 A FR8006516 A FR 8006516A FR 8006516 A FR8006516 A FR 8006516A FR 2452485 B1 FR2452485 B1 FR 2452485B1
- Authority
- FR
- France
- Prior art keywords
- quinoleinecarboxylic
- antisecretory
- esters
- acids
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2398179A | 1979-03-26 | 1979-03-26 | |
US06/127,153 US4343804A (en) | 1979-03-26 | 1980-03-04 | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2452485A1 FR2452485A1 (fr) | 1980-10-24 |
FR2452485B1 true FR2452485B1 (fr) | 1986-09-12 |
Family
ID=26697875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8006516A Expired FR2452485B1 (fr) | 1979-03-26 | 1980-03-24 | Nouveaux acides et esters 4-amino-3-quinoleinecarboxyliques, utiles notamment comme agents antisecretoires et anti-ulcere |
Country Status (31)
Country | Link |
---|---|
US (1) | US4343804A (fr) |
JP (1) | JPH02117663A (fr) |
AR (1) | AR230268A1 (fr) |
AT (1) | AT372373B (fr) |
AU (1) | AU528388B2 (fr) |
BR (1) | BR8001779A (fr) |
CA (1) | CA1147338A (fr) |
CH (1) | CH644105A5 (fr) |
DE (1) | DE3011490A1 (fr) |
DK (1) | DK156056C (fr) |
EG (1) | EG15009A (fr) |
ES (1) | ES8103048A1 (fr) |
FI (1) | FI77452C (fr) |
FR (1) | FR2452485B1 (fr) |
GB (1) | GB2047244B (fr) |
GR (1) | GR68006B (fr) |
HK (1) | HK67983A (fr) |
IE (1) | IE49577B1 (fr) |
IL (1) | IL59628A (fr) |
IN (1) | IN151446B (fr) |
IT (1) | IT1133079B (fr) |
MX (1) | MX6264E (fr) |
NL (1) | NL8001752A (fr) |
NO (1) | NO153927C (fr) |
NZ (1) | NZ193252A (fr) |
PH (1) | PH16416A (fr) |
PL (1) | PL125030B1 (fr) |
PT (1) | PT71008B (fr) |
SE (1) | SE435837B (fr) |
SG (1) | SG33683G (fr) |
YU (1) | YU41702B (fr) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8610981D0 (en) * | 1986-05-06 | 1986-06-11 | Ici America Inc | Quinoline amides |
GB8621425D0 (en) * | 1986-09-05 | 1986-10-15 | Smith Kline French Lab | Compounds |
GB8804446D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804443D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804448D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804444D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804447D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
GB8804445D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
US5432182A (en) * | 1989-02-23 | 1995-07-11 | Smithkline Beecham Intercredit B.V. | Compounds substituted quinoline derivatives |
CA2011086A1 (fr) * | 1989-03-17 | 1990-09-17 | Karl-Heinz Geiss | 2-alkyl-4-arylmethylaminoquinolines, leur utilisation et medicaments les contenant |
DE3917233A1 (de) * | 1989-05-26 | 1990-11-29 | Basf Ag | 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel |
GB8918265D0 (en) * | 1989-08-10 | 1989-09-20 | Smithkline Beckman Intercredit | Compounds |
US5362743A (en) * | 1993-03-09 | 1994-11-08 | Pfizer Inc. | Aminoquinoline derivatives |
US5556863A (en) * | 1993-06-11 | 1996-09-17 | Astra Aktiebolag | Compound for gastric acid secretion inhibition |
IS4164A (is) * | 1993-06-11 | 1994-12-12 | Ab Astra | Efnasambönd sem hindra flæði magasýru |
CA2167154A1 (fr) * | 1993-08-10 | 1995-02-16 | Sarkis Barret Kalindjian | Ligands aux recepteurs de cck ou de gastrine |
US5650415A (en) * | 1995-06-07 | 1997-07-22 | Sugen, Inc. | Quinoline compounds |
KR0169813B1 (ko) * | 1995-07-12 | 1999-01-15 | 김종인 | 4-아미노-3-아실나프티리딘 유도체 |
US5760041A (en) * | 1996-02-05 | 1998-06-02 | American Cyanamid Company | 4-aminoquinazoline EGFR Inhibitors |
US6875769B2 (en) * | 1996-05-23 | 2005-04-05 | Pfizer Inc. | Substituted6,6-hetero-bicyclicderivatives |
US5929080A (en) * | 1997-05-06 | 1999-07-27 | American Cyanamid Company | Method of treating polycystic kidney disease |
US6251912B1 (en) | 1997-08-01 | 2001-06-26 | American Cyanamid Company | Substituted quinazoline derivatives |
US6323209B1 (en) | 1997-11-06 | 2001-11-27 | American Cyanamid Company | Method of treating or inhibiting colonic polyps |
BRPI9914164B8 (pt) | 1998-09-29 | 2021-05-25 | American Cyanamid Co | compostos de 3-ciano quinolina |
AU776933B2 (en) * | 1999-12-28 | 2004-09-23 | Eisai R&D Management Co., Ltd. | Heterocyclic compounds having sulfonamide groups |
US6521618B2 (en) | 2000-03-28 | 2003-02-18 | Wyeth | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors |
US6576644B2 (en) * | 2000-09-06 | 2003-06-10 | Bristol-Myers Squibb Co. | Quinoline inhibitors of cGMP phosphodiesterase |
UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
MY140561A (en) * | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
US8293751B2 (en) | 2003-01-14 | 2012-10-23 | Arena Pharmaceuticals, Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
SI1606261T1 (sl) | 2003-03-10 | 2010-03-31 | Nycomed Gmbh | Novi postopek za pripravo roflumilasta |
JP4920410B2 (ja) * | 2003-07-14 | 2012-04-18 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 代謝モジュレーターとしての縮合アリールおよびヘテロアリール誘導体ならびに代謝に関連する障害の予防および治療 |
EP1861074B1 (fr) * | 2005-03-16 | 2013-04-24 | Takeda GmbH | Forme de dosage cachant le goût comprenant du roflumilaste |
WO2011022216A1 (fr) * | 2009-08-17 | 2011-02-24 | High Point Pharmaceuticals, Llc | Dérivés de pyridine substitués, compositions pharmaceutiques et procédés d'utilisation pour traiter le stress oxydatif |
EP2528894A1 (fr) | 2010-01-27 | 2012-12-05 | Arena Pharmaceuticals, Inc. | Procédés de préparation d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclopenta[b]indol-3-yl) acétique et de ses sels |
EP2619198A1 (fr) | 2010-09-22 | 2013-07-31 | Arena Pharmaceuticals, Inc. | Modulateurs du récepteur gpr119 et traitement des troubles qui lui sont liés |
AU2016205361C1 (en) | 2015-01-06 | 2021-04-08 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
DK3310760T3 (da) | 2015-06-22 | 2022-10-24 | Arena Pharm Inc | Krystallinsk L-argininsalt af (R)-2-(7-(4-cyclopentyl-3-(trifluormethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3- yl)eddikesyre til anvendelse ved S1P1-receptor-associerede lidelser |
ES2884073T3 (es) * | 2016-11-11 | 2021-12-10 | Bayer Animal Health Gmbh | Nuevos derivados antihelmínticos de quinolina-3-carboxamida |
CA3053418A1 (fr) | 2017-02-16 | 2018-08-23 | Arena Pharmaceuticals, Inc. | Composes et methodes de traitement de l'angiocholite biliaire primitive |
EP3700527A4 (fr) * | 2017-10-25 | 2021-03-10 | Children's Medical Center Corporation | Inhibiteurs de papd5 et leurs méthodes d'utilisation |
JP7403472B2 (ja) | 2018-05-09 | 2023-12-22 | バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 新規キノリン誘導体 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3470186A (en) * | 1967-06-02 | 1969-09-30 | American Cyanamid Co | Substituted 4-anilino-3-quinolinecarboxylic acids and esters |
JPS4838712A (fr) * | 1971-09-18 | 1973-06-07 |
-
1980
- 1980-03-04 US US06/127,153 patent/US4343804A/en not_active Expired - Lifetime
- 1980-03-14 IL IL59628A patent/IL59628A/xx unknown
- 1980-03-22 GR GR61513A patent/GR68006B/el unknown
- 1980-03-24 FR FR8006516A patent/FR2452485B1/fr not_active Expired
- 1980-03-24 AT AT0156480A patent/AT372373B/de not_active IP Right Cessation
- 1980-03-24 IE IE605/80A patent/IE49577B1/en unknown
- 1980-03-24 FI FI800910A patent/FI77452C/fi not_active IP Right Cessation
- 1980-03-24 MX MX808722U patent/MX6264E/es unknown
- 1980-03-25 GB GB8009991A patent/GB2047244B/en not_active Expired
- 1980-03-25 CH CH234080A patent/CH644105A5/fr not_active IP Right Cessation
- 1980-03-25 DE DE19803011490 patent/DE3011490A1/de active Granted
- 1980-03-25 PT PT71008A patent/PT71008B/pt unknown
- 1980-03-25 NZ NZ193252A patent/NZ193252A/en unknown
- 1980-03-25 PH PH23804A patent/PH16416A/en unknown
- 1980-03-25 EG EG80174A patent/EG15009A/xx active
- 1980-03-25 IN IN345/CAL/80A patent/IN151446B/en unknown
- 1980-03-25 PL PL1980222993A patent/PL125030B1/pl unknown
- 1980-03-25 DK DK128380A patent/DK156056C/da not_active IP Right Cessation
- 1980-03-25 NO NO800858A patent/NO153927C/no unknown
- 1980-03-25 NL NL8001752A patent/NL8001752A/nl not_active Application Discontinuation
- 1980-03-25 SE SE8002292A patent/SE435837B/sv not_active IP Right Cessation
- 1980-03-25 ES ES489887A patent/ES8103048A1/es not_active Expired
- 1980-03-25 BR BR8001779A patent/BR8001779A/pt unknown
- 1980-03-26 IT IT67465/80A patent/IT1133079B/it active
- 1980-03-26 AU AU56848/80A patent/AU528388B2/en not_active Ceased
- 1980-03-26 AR AR280455A patent/AR230268A1/es active
- 1980-03-26 CA CA000348417A patent/CA1147338A/fr not_active Expired
- 1980-03-26 YU YU844/80A patent/YU41702B/xx unknown
-
1983
- 1983-06-13 SG SG336/83A patent/SG33683G/en unknown
- 1983-12-15 HK HK679/83A patent/HK67983A/xx unknown
-
1989
- 1989-09-26 JP JP1250369A patent/JPH02117663A/ja active Pending
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |