NZ193252A - 4-amino-3-quinoline carboxylic acid derivatives and pharmaceutical compositions - Google Patents

4-amino-3-quinoline carboxylic acid derivatives and pharmaceutical compositions

Info

Publication number
NZ193252A
NZ193252A NZ193252A NZ19325280A NZ193252A NZ 193252 A NZ193252 A NZ 193252A NZ 193252 A NZ193252 A NZ 193252A NZ 19325280 A NZ19325280 A NZ 19325280A NZ 193252 A NZ193252 A NZ 193252A
Authority
NZ
New Zealand
Prior art keywords
ethyl
amino
methoxy
quinolinecarboxylate
compound
Prior art date
Application number
NZ193252A
Other languages
English (en)
Inventor
Jr H R Munson
R S Alpin
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of NZ193252A publication Critical patent/NZ193252A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ193252A 1979-03-26 1980-03-25 4-amino-3-quinoline carboxylic acid derivatives and pharmaceutical compositions NZ193252A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds

Publications (1)

Publication Number Publication Date
NZ193252A true NZ193252A (en) 1984-04-27

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ193252A NZ193252A (en) 1979-03-26 1980-03-25 4-amino-3-quinoline carboxylic acid derivatives and pharmaceutical compositions

Country Status (31)

Country Link
US (1) US4343804A (enExample)
JP (1) JPH02117663A (enExample)
AR (1) AR230268A1 (enExample)
AT (1) AT372373B (enExample)
AU (1) AU528388B2 (enExample)
BR (1) BR8001779A (enExample)
CA (1) CA1147338A (enExample)
CH (1) CH644105A5 (enExample)
DE (1) DE3011490A1 (enExample)
DK (1) DK156056C (enExample)
EG (1) EG15009A (enExample)
ES (1) ES489887A0 (enExample)
FI (1) FI77452C (enExample)
FR (1) FR2452485B1 (enExample)
GB (1) GB2047244B (enExample)
GR (1) GR68006B (enExample)
HK (1) HK67983A (enExample)
IE (1) IE49577B1 (enExample)
IL (1) IL59628A (enExample)
IN (1) IN151446B (enExample)
IT (1) IT1133079B (enExample)
MX (1) MX6264E (enExample)
NL (1) NL8001752A (enExample)
NO (1) NO153927C (enExample)
NZ (1) NZ193252A (enExample)
PH (1) PH16416A (enExample)
PL (1) PL125030B1 (enExample)
PT (1) PT71008B (enExample)
SE (1) SE435837B (enExample)
SG (1) SG33683G (enExample)
YU (1) YU41702B (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
PL181782B1 (pl) * 1993-08-10 2001-09-28 Black James Foundation Nowe zwiazki i sposób wytwarzania nowych zwiazków PL
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
HU230728B1 (hu) 1998-09-29 2017-12-28 Wyeth Holdings Llc Szubsztituált 3-cianokinolinok mint protein tirozin kinázok inhibitorai
ES2246922T3 (es) * 1999-12-28 2006-03-01 Eisai Co., Ltd. Compuestos heterociclicos que tienen grupos de sulfonamida.
US6521618B2 (en) * 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
RS20050532A (sr) 2003-01-14 2007-12-31 Arena Pharmaceuticals Inc., Derivati 1,2,3-trisupstituisanog arila i heteroarila kao modulatori metabolizma za profilaksu i tretman poremećaja povezanih sa njim, kao što su dijebetes i hiperglikemija
EA009985B1 (ru) 2003-03-10 2008-04-28 Никомед Гмбх Новый способ получения рофлумиласта
KR20060056944A (ko) * 2003-07-14 2006-05-25 아레나 파마슈티칼스, 인크. 대사 조절제로서 융합된 아릴 및 헤테로아릴 유도체 및이에 관련된 장애의 예방 또는 치료
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
EP2528894A1 (en) 2010-01-27 2012-12-05 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
CN103221410B (zh) 2010-09-22 2017-09-15 艾尼纳制药公司 Gpr119受体调节剂和对与其相关的障碍的治疗
CA3002540C (en) 2015-01-06 2023-11-07 Arena Pharmaceuticals, Inc. Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor
JP6838744B2 (ja) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩
MY196327A (en) * 2016-11-11 2023-03-24 Bayer Animal Health Gmbh New Anthelmintic Quinoline-3-Carboxamide Derivative
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
EP3700527A4 (en) * 2017-10-25 2021-03-10 Children's Medical Center Corporation PAPD5 INHIBITORS AND METHOD OF USING THEM
CN112074514B (zh) 2018-05-09 2024-10-29 礼蓝动物保健有限公司 新的喹啉衍生物
JP7397011B2 (ja) 2018-06-06 2023-12-12 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１ｐ１受容体に関連する状態を治療する方法
EP3959197A4 (en) 2019-04-24 2022-10-12 Children's Medical Center Corporation PAPD5 INHIBITORS AND METHODS OF USE THEREOF

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (enExample) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
HK67983A (en) 1983-12-23
AR230268A1 (es) 1984-03-01
YU41702B (en) 1987-12-31
FI77452C (fi) 1989-03-10
NO800858L (no) 1980-09-29
GR68006B (enExample) 1981-10-26
MX6264E (es) 1985-02-19
PL222993A1 (enExample) 1981-01-30
JPH02117663A (ja) 1990-05-02
GB2047244B (en) 1983-02-23
CA1147338A (en) 1983-05-31
IT1133079B (it) 1986-07-09
NO153927C (no) 1986-06-18
AU5684880A (en) 1980-10-02
US4343804A (en) 1982-08-10
IL59628A0 (en) 1980-06-30
PH16416A (en) 1983-09-29
CH644105A5 (fr) 1984-07-13
FR2452485B1 (fr) 1986-09-12
AT372373B (de) 1983-09-26
PT71008B (en) 1981-06-25
DK128380A (da) 1980-09-27
BR8001779A (pt) 1980-11-18
IN151446B (enExample) 1983-04-23
NL8001752A (nl) 1980-09-30
IL59628A (en) 1983-06-15
IE49577B1 (en) 1985-10-30
YU84480A (en) 1983-10-31
EG15009A (en) 1985-03-31
DK156056C (da) 1989-11-06
FI800910A7 (fi) 1980-09-27
ES8103048A1 (es) 1981-02-16
IT8067465A0 (it) 1980-03-26
DK156056B (da) 1989-06-19
SG33683G (en) 1985-03-29
ES489887A0 (es) 1981-02-16
FR2452485A1 (fr) 1980-10-24
IE800605L (en) 1980-09-26
AU528388B2 (en) 1983-04-28
PT71008A (en) 1980-04-01
ATA156480A (de) 1983-02-15
SE8002292L (sv) 1980-09-27
NO153927B (no) 1986-03-10
PL125030B1 (en) 1983-03-31
SE435837B (sv) 1984-10-22
DE3011490C2 (enExample) 1988-12-22
FI77452B (fi) 1988-11-30
GB2047244A (en) 1980-11-26
DE3011490A1 (de) 1981-03-12

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