CA2913346A1 - Modulation of targeted nerve fibers - Google Patents
Modulation of targeted nerve fibersInfo
- Publication number
- CA2913346A1 CA2913346A1 CA2913346A CA2913346A CA2913346A1 CA 2913346 A1 CA2913346 A1 CA 2913346A1 CA 2913346 A CA2913346 A CA 2913346A CA 2913346 A CA2913346 A CA 2913346A CA 2913346 A1 CA2913346 A1 CA 2913346A1
- Authority
- CA
- Canada
- Prior art keywords
- electrode
- catheter
- bend
- hepatic
- hepatic artery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Landscapes
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Applications Claiming Priority (5)
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| US201361831507P | 2013-06-05 | 2013-06-05 | |
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| US201361906830P | 2013-11-20 | 2013-11-20 | |
| US61/906,830 | 2013-11-20 | ||
| PCT/US2014/040949 WO2014197625A1 (en) | 2013-06-05 | 2014-06-04 | Modulation of targeted nerve fibers |
Publications (1)
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| US20140018880A1 (en) | 2002-04-08 | 2014-01-16 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
| US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
| US7756583B2 (en) | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
| US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US7335180B2 (en) | 2003-11-24 | 2008-02-26 | Flowcardia, Inc. | Steerable ultrasound catheter |
| US7758510B2 (en) | 2003-09-19 | 2010-07-20 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
| US11376061B2 (en) | 2008-11-11 | 2022-07-05 | Covidien Lp | Energy delivery device and methods of use |
| US11998266B2 (en) | 2009-10-12 | 2024-06-04 | Otsuka Medical Devices Co., Ltd | Intravascular energy delivery |
| TW201223583A (en) | 2010-10-25 | 2012-06-16 | Medtronic Ardian Luxembourg | Catheter apparatuses having multi-electrode arrays for renal neuromodulation and associated systems and methods |
| KR20130131471A (ko) | 2011-04-08 | 2013-12-03 | 코비디엔 엘피 | 신장 교감 신경의 신경차단 및 이온영동 약물 전달을 위한 이온영동 약물 전달 시스템 및 방법 |
| CN103930061B (zh) | 2011-04-25 | 2016-09-14 | 美敦力阿迪安卢森堡有限责任公司 | 用于限制导管壁低温消融的有关低温球囊限制部署的装置及方法 |
| CN107080561B (zh) | 2011-12-09 | 2020-09-11 | 麦特文申公司 | 用于神经调节的设备、系统和方法 |
| US20150111918A1 (en) | 2012-03-08 | 2015-04-23 | Medtronic Ardian Luxembourg S.a.r.l | Immune system neuromodulation and associated systems and methods |
| CA2872189A1 (en) | 2012-05-11 | 2013-11-14 | William W. CHANG | Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods |
| RU2640564C2 (ru) | 2012-08-02 | 2018-01-09 | Бард Периферэл Васкьюлар | Ультразвуковая катетерная система |
| CN104902836B (zh) | 2012-11-05 | 2017-08-08 | 毕达哥拉斯医疗有限公司 | 受控组织消融 |
| US9827036B2 (en) | 2012-11-13 | 2017-11-28 | Pulnovo Medical (Wuxi) Co., Ltd. | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| US11241267B2 (en) | 2012-11-13 | 2022-02-08 | Pulnovo Medical (Wuxi) Co., Ltd | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| US12082868B2 (en) | 2012-11-13 | 2024-09-10 | Pulnovo Medical (Wuxi) Co., Ltd. | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| CN102908191A (zh) * | 2012-11-13 | 2013-02-06 | 陈绍良 | 多极同步肺动脉射频消融导管 |
| US9179974B2 (en) | 2013-03-15 | 2015-11-10 | Medtronic Ardian Luxembourg S.A.R.L. | Helical push wire electrode |
| EP3003191A4 (en) | 2013-06-05 | 2017-02-08 | Metavention, Inc. | Modulation of targeted nerve fibers |
| US20150073515A1 (en) | 2013-09-09 | 2015-03-12 | Medtronic Ardian Luxembourg S.a.r.I. | Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods |
| CA2932765A1 (en) | 2013-12-05 | 2015-06-11 | Rfemb Holdings, Llc | Cancer immunotherapy by radiofrequency electrical membrane breakdown (rf-emb) |
| US10390943B2 (en) | 2014-03-17 | 2019-08-27 | Evalve, Inc. | Double orifice device for transcatheter mitral valve replacement |
| EP3125738A4 (en) * | 2014-03-31 | 2017-12-06 | Human Extensions Ltd. | Steerable medical device |
| JP2017513600A (ja) | 2014-04-24 | 2017-06-01 | メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ | 編組シャフトを有する神経調節カテーテル及び関連システム及び方法 |
| US10709490B2 (en) | 2014-05-07 | 2020-07-14 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods |
| CN106659531A (zh) | 2014-05-07 | 2017-05-10 | 毕达哥拉斯医疗有限公司 | 受控组织消融技术 |
| US11464971B2 (en) | 2014-08-26 | 2022-10-11 | Avent, Inc. | Selective nerve fiber block method and system |
| WO2016075536A2 (en) * | 2014-11-14 | 2016-05-19 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses for modulation of nerves in communication with the pulmonary system and associated systems and methods |
| WO2016090175A1 (en) | 2014-12-03 | 2016-06-09 | Metavention, Inc. | Systems and methods for modulating nerves or other tissue |
| US9974946B2 (en) * | 2015-04-07 | 2018-05-22 | NeuroTronik IP Holding (Jersey) Limited | Inflatable intravascular electrode supports for neuromodulation |
| US20180236220A1 (en) * | 2015-01-14 | 2018-08-23 | NeuroTronik IP Holding (Jersey) Limited | Inflatable intravascular electrode supports for neuromodulation |
| JP6723249B2 (ja) | 2015-01-30 | 2020-07-15 | アールエフイーエムビー ホールディングス リミテッド ライアビリティ カンパニー | 軟部組織を切除するためのシステムおよび方法 |
| US10376308B2 (en) | 2015-02-05 | 2019-08-13 | Axon Therapies, Inc. | Devices and methods for treatment of heart failure by splanchnic nerve ablation |
| US20180036511A1 (en) * | 2015-02-13 | 2018-02-08 | Cathrx Ltd | Improved catheter handle |
| WO2016132330A1 (en) * | 2015-02-20 | 2016-08-25 | Glaxosmithkline Intellectual Property Development Limited | Neuromodulation device |
| EP3278713B1 (en) * | 2015-03-30 | 2020-01-01 | Terumo Kabushiki Kaisha | Oct image processing device and method |
| US10383685B2 (en) | 2015-05-07 | 2019-08-20 | Pythagoras Medical Ltd. | Techniques for use with nerve tissue |
| US12268433B2 (en) | 2015-05-12 | 2025-04-08 | National University Of Ireland, Galway | Devices for therapeutic nasal neuromodulation and associated methods and systems |
| CN115040232A (zh) | 2015-05-12 | 2022-09-13 | 爱尔兰国立高威大学 | 用于治疗性鼻神经调节的装置及相关的方法和系统 |
| US20200147345A1 (en) * | 2015-08-17 | 2020-05-14 | Albert J. Sinusas | Real-time molecular imaging and minimally-invasive detection in interventional cardiology |
| WO2017041889A2 (en) * | 2015-09-07 | 2017-03-16 | Ablacon Inc. | Elongated medical device suitable for intravascular insertion and method of making an elongated medical device suitable for intravascular insertion |
| US11213340B2 (en) * | 2015-10-16 | 2022-01-04 | Medtronic, Inc. | Therapy to treat pelvic floor dysfunction and/or pain |
| ES2571460B1 (es) * | 2015-10-23 | 2017-01-05 | Indiba, S.A. | Procedimiento cosmético para la reducción o prevención de la acumulación de tejido adiposo |
| US10500373B2 (en) | 2015-12-04 | 2019-12-10 | Project Moray, Inc. | Lateral articulation anchors for catheters and other uses |
| US10660702B2 (en) * | 2016-01-05 | 2020-05-26 | Farapulse, Inc. | Systems, devices, and methods for focal ablation |
| CA3011460A1 (en) | 2016-01-15 | 2017-07-20 | Rfemb Holdings, Llc | Immunologic treatment of cancer |
| AU2017213756B2 (en) * | 2016-02-01 | 2020-01-16 | Medtronic Af Luxembourg S.A.R.L. | Systems and methods for monitoring and evaluating neuromodulation therapy |
| WO2017165810A1 (en) | 2016-03-25 | 2017-09-28 | Phillip Laby | Fluid-actuated sheath displacement and articulation behavior improving systems, devices, and methods for catheters, continuum manipulators, and other uses |
| US11420021B2 (en) | 2016-03-25 | 2022-08-23 | Project Moray, Inc. | Fluid-actuated displacement for catheters, continuum manipulators, and other uses |
| US11229454B2 (en) * | 2016-05-06 | 2022-01-25 | Cardioscout Solutions, Inc. | Access devices and methods for treatment of medical conditions and delivery of injectables |
| WO2017199240A2 (en) | 2016-05-18 | 2017-11-23 | Pythagoras Medical Ltd. | Helical catheter |
| KR20190015357A (ko) | 2016-05-31 | 2019-02-13 | 세다르스-신나이 메디칼 센터 | 체내 자외선 치료 |
| DE102016110137A1 (de) * | 2016-06-01 | 2017-12-07 | Medizinische Hochschule Hannover | Formadaptives medizinisches Implantat sowie Verwendung einer elektrischen Signalquelle |
| US10524859B2 (en) | 2016-06-07 | 2020-01-07 | Metavention, Inc. | Therapeutic tissue modulation devices and methods |
| CN106037930B (zh) * | 2016-06-15 | 2019-07-12 | 上海市胸科医院 | 一种微波消融软杆针 |
| CA3029260A1 (en) | 2016-06-27 | 2018-01-04 | Gala Therapeutics, Inc. | Generator and a catheter with an electrode and a method for treating a lung passageway |
| US12403305B2 (en) | 2016-06-27 | 2025-09-02 | Galvanize Therapeutics, Inc. | Immunostimulation in the treatment of viral infection |
| US11504064B2 (en) * | 2016-07-28 | 2022-11-22 | Evalve, Inc. | Systems and methods for intra-procedural cardiac pressure monitoring |
| CN114711957A (zh) * | 2016-07-29 | 2022-07-08 | 阿克松疗法公司 | 通过脏神经消融术治疗心脏衰竭的装置、系统和方法 |
| WO2018028805A1 (en) * | 2016-08-12 | 2018-02-15 | Medical Development Technologies S.A. | Blood-flow interrupting means for insulating an implant device for ablation |
| CN110603005A (zh) * | 2016-09-28 | 2019-12-20 | 项目莫里股份有限公司 | 心律失常诊断和/或治疗的递送方法和装置，以及用于其它用途的机器人系统 |
| WO2018064400A1 (en) | 2016-09-28 | 2018-04-05 | Project Moray, Inc. | Base station, charging station, and/or server for robotic catheter systems and other uses, and improved articulated devices and systems |
| JP7049326B2 (ja) | 2016-10-04 | 2022-04-06 | アヴェント インコーポレイテッド | 冷却型ｒｆプローブ |
| AU2017348440C1 (en) * | 2016-10-31 | 2023-07-20 | GE Precision Healthcare LLC | Techniques for neuromodulation |
| PT3534852T (pt) | 2016-11-02 | 2022-03-22 | Miraki Innovation Think Tank Llc | Dispositivos para geração de suspensão espessa |
| US10363138B2 (en) | 2016-11-09 | 2019-07-30 | Evalve, Inc. | Devices for adjusting the curvature of cardiac valve structures |
| US10426616B2 (en) * | 2016-11-17 | 2019-10-01 | Evalve, Inc. | Cardiac implant delivery system |
| US11324673B2 (en) | 2016-11-18 | 2022-05-10 | Miraki Innovation Think Tank Llc | Cosmetic appearance of skin |
| US20180140321A1 (en) * | 2016-11-23 | 2018-05-24 | C. R. Bard, Inc. | Catheter With Retractable Sheath And Methods Thereof |
| EP3500199B1 (en) * | 2016-11-29 | 2021-07-28 | St. Jude Medical, Cardiology Division, Inc. | Electroporation systems and catheters for electroporation systems |
| US20180168836A1 (en) * | 2016-12-20 | 2018-06-21 | W. L. Gore & Associates, Inc. | Anticannulation web |
| US10582983B2 (en) | 2017-02-06 | 2020-03-10 | C. R. Bard, Inc. | Ultrasonic endovascular catheter with a controllable sheath |
| US20190380761A1 (en) * | 2017-02-28 | 2019-12-19 | University Of Florida Research Foundation, Inc. | Controlling esophageal temperature during cardiac ablation |
| SG11201909303TA (en) | 2017-04-05 | 2019-11-28 | Miraki Innovation Think Tank Llc | Point of delivery cold slurry generation |
| WO2018187581A1 (en) | 2017-04-05 | 2018-10-11 | Arctic Fox Biomedical, Inc. | Cold slurry containment |
| WO2018200537A1 (en) | 2017-04-25 | 2018-11-01 | Project Moray, Inc. | Matrix supported balloon articulation systems, devices, and methods for catheters and other users |
| WO2018229768A2 (en) * | 2017-06-13 | 2018-12-20 | The Trendlines Group Ltd. | Intravein ablation |
| AU2018204841B2 (en) * | 2017-07-05 | 2023-08-10 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for treating post-traumatic stress disorder in patients via renal neuromodulation |
| US11666379B2 (en) * | 2017-07-06 | 2023-06-06 | Biosense Webster (Israel) Ltd. | Temperature controlled short duration ablation with multiple electrodes |
| CN113712560A (zh) | 2017-08-03 | 2021-11-30 | 墨尔本大学 | 用于感测和或刺激组织的医疗设备 |
| US10500342B2 (en) | 2017-08-21 | 2019-12-10 | Miraki Innovation Think Tank Llc | Cold slurry syringe |
| US11160602B2 (en) * | 2017-08-29 | 2021-11-02 | Cilag Gmbh International | Control of surgical field irrigation |
| US10675082B2 (en) | 2017-08-29 | 2020-06-09 | Ethicon Llc | Control of surgical field irrigation by electrosurgical tool |
| US11338135B2 (en) | 2017-10-23 | 2022-05-24 | Cardiac Pacemakers, Inc. | Medical devices for cancer therapy with electric field shaping elements |
| US12403306B2 (en) | 2017-10-23 | 2025-09-02 | Cardiac Pacemakers, Inc. | Electric field shaping leads for treatment of cancer |
| EP3703809A1 (en) * | 2017-11-02 | 2020-09-09 | Boston Scientific Scimed, Inc. | System and method for providing glucose control therapy |
| US12251525B2 (en) | 2017-11-07 | 2025-03-18 | Children's Medical Center Corporation | Interventional device with adjustable configuration |
| US12017022B2 (en) | 2017-11-17 | 2024-06-25 | Isola Therapeutics, Inc. | Devices and systems for intraluminal local drug delivery |
| EP3710096A1 (en) | 2017-11-17 | 2020-09-23 | Convergascent LLC | Devices and systems for intraluminal local drug delivery |
| US10561461B2 (en) | 2017-12-17 | 2020-02-18 | Axon Therapies, Inc. | Methods and devices for endovascular ablation of a splanchnic nerve |
| US11633601B2 (en) | 2017-12-20 | 2023-04-25 | Galvani Bioelectronics Limited | Treatment of inflammatory disorders |
| US11446502B2 (en) | 2017-12-20 | 2022-09-20 | Galvani Bioelectronics Limited | Stimulation of a nerve supplying the spleen |
| WO2019122907A1 (en) * | 2017-12-20 | 2019-06-27 | Galvani Bioelectronics Limited | Treatment of acute medical conditions |
| ES2988485T3 (es) | 2017-12-20 | 2024-11-20 | Galvani Bioelectronics Ltd | Tratamiento de afecciones médicas agudas |
| JP2021507759A (ja) | 2017-12-20 | 2021-02-25 | ガルバニ バイオエレクトロニクス リミテッド | 炎症に関連する疾患の治療 |
| CN111698959B (zh) | 2017-12-26 | 2023-07-11 | 盖能适治疗股份有限公司 | 用于疾病状态和病症的治疗的方法、装置和系统 |
| JP2021508533A (ja) | 2017-12-26 | 2021-03-11 | ギャラリー，インコーポレイテッド | 様々な用途のためのエネルギー送達の最適化 |
| CN111526835B (zh) * | 2018-01-02 | 2024-07-02 | 圣犹达医疗用品心脏病学部门有限公司 | 包括远侧环的电穿孔导管 |
| CN111886043B (zh) | 2018-01-26 | 2024-03-29 | 阿克松疗法公司 | 用于内脏神经血管内消融的方法和装置 |
| JP6905230B2 (ja) * | 2018-01-31 | 2021-07-21 | 国立大学法人広島大学 | 塞栓術装置 |
| US11160975B2 (en) * | 2018-03-02 | 2021-11-02 | Aleva Neurotherapeutics | Apparatus for stimulation of autonomic nervous system |
| AU2019236304B2 (en) * | 2018-03-15 | 2024-08-01 | Avent Investment, Llc | System and method to percutaneously block painful sensations |
| WO2019189702A1 (ja) * | 2018-03-28 | 2019-10-03 | 株式会社Ａｌｉｖａｓ | 処置方法および医療デバイス |
| US10974079B2 (en) * | 2018-08-29 | 2021-04-13 | General Electric Company | Neuromodulation techniques |
| CN109011228B (zh) * | 2018-09-06 | 2019-08-16 | 西安交通大学 | 一种高空间分辨率超声神经调控方法及系统 |
| EP3866715A4 (en) * | 2018-10-17 | 2022-11-16 | University of Florida Research Foundation | Controlling esophageal temperature during cardiac ablation |
| CN109350232A (zh) * | 2018-12-10 | 2019-02-19 | 深圳华焊生物科技有限公司 | 一种生物组织焊接系统 |
| US11547472B2 (en) | 2018-12-11 | 2023-01-10 | Neurent Medical Limited | Systems and methods for therapeutic nasal neuromodulation |
| CN211862951U (zh) * | 2019-02-03 | 2020-11-06 | 上海魅丽纬叶医疗科技有限公司 | 一种具有活动导丝功能的射频消融导管 |
| US11779391B2 (en) * | 2019-02-28 | 2023-10-10 | Biosense Webster (Israel) Ltd. | Forming a lesion based on pre-determined amount of abaltive energy vs lesion size curve |
| GB2582826B (en) * | 2019-04-05 | 2021-09-08 | Guided Ultrasonics Ltd | Ultrasonic sensor for guided wave testing |
| WO2020219339A1 (en) | 2019-04-22 | 2020-10-29 | Boston Scientific Scimed, Inc. | Combination electrical and chemotherapeutic treatment of cancer |
| CN113766949B (zh) | 2019-04-22 | 2025-04-08 | 波士顿科学国际有限公司 | 用于施用电刺激以治疗癌症的系统 |
| EP4378519A1 (en) | 2019-04-22 | 2024-06-05 | Boston Scientific Scimed, Inc. | Electrical stimulation devices for cancer treatment |
| WO2020219517A2 (en) | 2019-04-23 | 2020-10-29 | Boston Scientific Scimed, Inc. | Electrical stimulation for cancer treatment with internal and external electrodes |
| CN113747936B (zh) | 2019-04-23 | 2024-06-18 | 波士顿科学国际有限公司 | 用于电刺激来治疗癌症的电极 |
| CN113766950A (zh) * | 2019-04-23 | 2021-12-07 | 波士顿科学国际有限公司 | 带有热治疗或热监测的电刺激 |
| US12213728B2 (en) * | 2019-05-01 | 2025-02-04 | Biosense Webster (Israel) Ltd. | Temperature controlled short duration ablation with resistive heating |
| US20200345403A1 (en) * | 2019-05-03 | 2020-11-05 | The Board Of Trustees Of The Leland Stanford Junior University | Instruments and methodology involving cryoablation |
| US11093038B2 (en) | 2019-05-14 | 2021-08-17 | Synchron Australia Pty Limited | Systems and methods for generic control using a neural signal |
| EP3986532A1 (en) * | 2019-06-19 | 2022-04-27 | Galvani Bioelectronics Limited | System for the treatment of disorders associated with inflammation |
| US20220241555A1 (en) * | 2019-06-20 | 2022-08-04 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | An endoscopic retrograde cholangiopancreatography (ercp) catheter and guidewire with sensors and methods of using the same |
| JP2022537018A (ja) | 2019-06-20 | 2022-08-23 | アクソン セラピーズ，インク． | 内臓神経の血管内アブレーションの方法及びデバイス |
| US11179575B2 (en) * | 2019-10-15 | 2021-11-23 | Cedars-Sinai Medical Center | Internal ultraviolet therapy |
| WO2021086972A1 (en) | 2019-10-29 | 2021-05-06 | Synchron Australia Pty Limited | Systems and methods for configuring a brain control interface using data from deployed systems |
| JP2022553602A (ja) * | 2019-11-05 | 2022-12-26 | バイオトロニック エスエー アンド カンパニー カーゲー | 操縦可能なカテーテル用のカテーテルチューブ、及び操縦可能なカテーテルによって埋め込み型医療装置を埋め込む方法 |
| WO2021097448A1 (en) * | 2019-11-15 | 2021-05-20 | Synchron Australia Pty Limited | Methods and devices for renal neuromodulation |
| CN111110177B (zh) * | 2020-01-14 | 2022-02-22 | 重庆市中医院 | 一种便携式鼻内窥镜 |
| ES2960299T3 (es) | 2020-01-17 | 2024-03-04 | Axon Therapies Inc | Dispositivos para la ablación endovascular de un nervio esplácnico |
| US11633630B2 (en) * | 2020-01-23 | 2023-04-25 | General Electric Company | Noninvasive tissue displacement control and monitoring for neuromodulation |
| US20230047610A1 (en) * | 2020-02-04 | 2023-02-16 | DP Holding (U.K) Limited | Devices and methods for selecting stents |
| US11883655B2 (en) | 2020-02-24 | 2024-01-30 | Boston Scientific Scimed, Inc. | Systems and methods for treatment of pancreatic cancer |
| US20230147752A1 (en) * | 2020-03-20 | 2023-05-11 | Cedars-Sinai Medical Center | Internal ultraviolet therapy |
| WO2021205229A1 (en) | 2020-04-09 | 2021-10-14 | Neurent Medical Limited | Systems and methods for improving sleep with therapeutic nasal treatment |
| WO2021205230A1 (en) | 2020-04-09 | 2021-10-14 | Neurent Medical Limited | Systems and methods for therapeutic nasal treatment |
| CN116744999A (zh) | 2020-08-13 | 2023-09-12 | 西达-赛奈医疗中心 | 内部紫外光疗法 |
| KR20220037903A (ko) * | 2020-09-18 | 2022-03-25 | (주) 타우피엔유메디칼 | 심방세동 시술용 카테터 및 이를 이용한 심방세동 시술 방법 |
| CN112190325B (zh) * | 2020-10-16 | 2021-04-27 | 韩从辉 | 膀胱息肉微创手术器械 |
| KR102296026B1 (ko) * | 2020-12-03 | 2021-09-02 | 주식회사 딥큐어 | 전극 장치 |
| CN116867455A (zh) * | 2021-02-05 | 2023-10-10 | 卡迪奥焦点公司 | 内窥镜引导的带耐热球囊的消融导管 |
| JP7761745B2 (ja) * | 2021-07-12 | 2025-10-28 | ボストン サイエンティフィック サイムド，インコーポレイテッド | 放射状にクロックされたステアラブルカテーテル |
| CA3234912A1 (en) * | 2021-10-13 | 2023-04-20 | Christopher Michael Puleo | Activation of late response genes using neuromodulation |
| FR3130168B1 (fr) * | 2021-12-10 | 2024-11-15 | Electroducer | Ensemble de stimulation trans-vasculaire d’une partie d’un système nerveux autonome d’un corps humain, notamment de stimulation trans-vasculaire nerveuse rénale ou de stimulation du glomus carotidien. |
| US12223106B2 (en) | 2022-01-13 | 2025-02-11 | Synchron Australia Pty Limited | Systems and methods for generic control using a neural signal |
| US11891808B2 (en) | 2022-01-19 | 2024-02-06 | Oatey Co. | Roof flashing |
| CN114699165B (zh) * | 2022-05-11 | 2024-12-24 | 上海安通医疗科技有限公司 | 一种适用于桡动脉的电记忆消融导管 |
| US20240099768A1 (en) * | 2022-09-22 | 2024-03-28 | Biosense Webster (Israel) Ltd. | Two-segment deflectin catheter with side exit guidwire lumen |
| EP4615353A1 (en) * | 2022-11-11 | 2025-09-17 | Stryker Corporation | Electrode probe for radiofrequency ablation |
| WO2025090651A1 (en) * | 2023-10-23 | 2025-05-01 | TriReme Medical, LLC | Balloon catheter |
| WO2025193513A1 (en) * | 2024-03-15 | 2025-09-18 | CRC EP, Inc. | Index for lesion prediction and safety using pulsed field ablation |
Family Cites Families (633)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4033331A (en) | 1975-07-17 | 1977-07-05 | Guss Stephen B | Cardiac catheter and method of using same |
| JPS6076937U (ja) | 1983-10-21 | 1985-05-29 | ハナコ・メデイカル株式会社 | 湾曲可能なリ−ドワイヤ− |
| US5231988A (en) | 1991-08-09 | 1993-08-03 | Cyberonics, Inc. | Treatment of endocrine disorders by nerve stimulation |
| US5683366A (en) | 1992-01-07 | 1997-11-04 | Arthrocare Corporation | System and method for electrosurgical tissue canalization |
| US5281218A (en) * | 1992-06-05 | 1994-01-25 | Cardiac Pathways Corporation | Catheter having needle electrode for radiofrequency ablation |
| US8728065B2 (en) | 2009-07-02 | 2014-05-20 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Apparatus and methods for contactless electrophysiology studies |
| EP0597463A3 (en) | 1992-11-13 | 1996-11-06 | Dornier Med Systems Inc | Thermotherapiesonde. |
| GB9302462D0 (en) | 1993-12-01 | 1993-12-01 | Semple Keith | Motor cycle centre-stand lock |
| US5680860A (en) | 1994-07-07 | 1997-10-28 | Cardiac Pathways Corporation | Mapping and/or ablation catheter with coilable distal extremity and method for using same |
| US6142994A (en) | 1994-10-07 | 2000-11-07 | Ep Technologies, Inc. | Surgical method and apparatus for positioning a diagnostic a therapeutic element within the body |
| US5707400A (en) | 1995-09-19 | 1998-01-13 | Cyberonics, Inc. | Treating refractory hypertension by nerve stimulation |
| US6419673B1 (en) | 1996-05-06 | 2002-07-16 | Stuart Edwards | Ablation of rectal and other internal body structures |
| US6022336A (en) | 1996-05-20 | 2000-02-08 | Percusurge, Inc. | Catheter system for emboli containment |
| US6464697B1 (en) | 1998-02-19 | 2002-10-15 | Curon Medical, Inc. | Stomach and adjoining tissue regions in the esophagus |
| US5893885A (en) | 1996-11-01 | 1999-04-13 | Cordis Webster, Inc. | Multi-electrode ablation catheter |
| US6235022B1 (en) | 1996-12-20 | 2001-05-22 | Cardiac Pathways, Inc | RF generator and pump apparatus and system and method for cooled ablation |
| US7220257B1 (en) | 2000-07-25 | 2007-05-22 | Scimed Life Systems, Inc. | Cryotreatment device and method |
| US6012457A (en) | 1997-07-08 | 2000-01-11 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
| US7048716B1 (en) | 1997-05-15 | 2006-05-23 | Stanford University | MR-compatible devices |
| JP3391466B2 (ja) | 1997-06-13 | 2003-03-31 | アースロケア コーポレイション | 閉塞した体内管腔の再疎通のための電気外科のカテーテルシステム及びカテーテル |
| US8000764B2 (en) | 1997-06-20 | 2011-08-16 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Electrophysiology/ablation catheter having second passage |
| US6514249B1 (en) | 1997-07-08 | 2003-02-04 | Atrionix, Inc. | Positioning system and method for orienting an ablation element within a pulmonary vein ostium |
| AU732188B2 (en) * | 1997-08-13 | 2001-04-12 | Surx, Inc. | Noninvasive devices, methods, and systems for shrinking of tissues |
| US6179832B1 (en) * | 1997-09-11 | 2001-01-30 | Vnus Medical Technologies, Inc. | Expandable catheter having two sets of electrodes |
| US6917834B2 (en) * | 1997-12-03 | 2005-07-12 | Boston Scientific Scimed, Inc. | Devices and methods for creating lesions in endocardial and surrounding tissue to isolate focal arrhythmia substrates |
| AU2114299A (en) | 1998-01-14 | 1999-08-02 | Conway-Stuart Medical, Inc. | Electrosurgical device for sphincter treatment |
| US6905494B2 (en) | 1998-03-31 | 2005-06-14 | Innercool Therapies, Inc. | Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection |
| US7001378B2 (en) | 1998-03-31 | 2006-02-21 | Innercool Therapies, Inc. | Method and device for performing cooling or cryo-therapies, for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection |
| US6558378B2 (en) | 1998-05-05 | 2003-05-06 | Cardiac Pacemakers, Inc. | RF ablation system and method having automatic temperature control |
| US6428537B1 (en) | 1998-05-22 | 2002-08-06 | Scimed Life Systems, Inc. | Electrophysiological treatment methods and apparatus employing high voltage pulse to render tissue temporarily unresponsive |
| US7198635B2 (en) | 2000-10-17 | 2007-04-03 | Asthmatx, Inc. | Modification of airways by application of energy |
| WO1999065561A1 (en) | 1998-06-19 | 1999-12-23 | Cordis Webster, Inc. | Method and apparatus for transvascular treatment of tachycardia and fibrillation |
| US7599736B2 (en) | 2001-07-23 | 2009-10-06 | Dilorenzo Biomedical, Llc | Method and apparatus for neuromodulation and physiologic modulation for the treatment of metabolic and neuropsychiatric disease |
| US6183468B1 (en) | 1998-09-10 | 2001-02-06 | Scimed Life Systems, Inc. | Systems and methods for controlling power in an electrosurgical probe |
| EP1126831A4 (en) * | 1998-10-06 | 2004-10-06 | Diamedica Inc | METHODS FOR TREATING INSULIN RESISTANCE BY NITROGEN MONOXYD OF LIVER |
| US6638278B2 (en) | 1998-11-23 | 2003-10-28 | C. R. Bard, Inc. | Intracardiac grasp catheter |
| US6178354B1 (en) | 1998-12-02 | 2001-01-23 | C. R. Bard, Inc. | Internal mechanism for displacing a slidable electrode |
| US6290697B1 (en) | 1998-12-01 | 2001-09-18 | Irvine Biomedical, Inc. | Self-guiding catheter system for tissue ablation |
| US6451011B2 (en) | 1999-01-19 | 2002-09-17 | Hosheng Tu | Medical device having temperature sensing and ablation capabilities |
| US6113593A (en) | 1999-02-01 | 2000-09-05 | Tu; Lily Chen | Ablation apparatus having temperature and force sensing capabilities |
| US6432102B2 (en) | 1999-03-15 | 2002-08-13 | Cryovascular Systems, Inc. | Cryosurgical fluid supply |
| US6648879B2 (en) | 1999-02-24 | 2003-11-18 | Cryovascular Systems, Inc. | Safety cryotherapy catheter |
| US20040249421A1 (en) | 2000-09-13 | 2004-12-09 | Impulse Dynamics Nv | Blood glucose level control |
| US9101765B2 (en) | 1999-03-05 | 2015-08-11 | Metacure Limited | Non-immediate effects of therapy |
| US8700161B2 (en) | 1999-03-05 | 2014-04-15 | Metacure Limited | Blood glucose level control |
| US6161049A (en) | 1999-03-26 | 2000-12-12 | Urologix, Inc. | Thermal therapy catheter |
| US6425877B1 (en) | 1999-04-02 | 2002-07-30 | Novasys Medical, Inc. | Treatment of tissue in the digestive circulatory respiratory urinary and reproductive systems |
| US6702811B2 (en) | 1999-04-05 | 2004-03-09 | Medtronic, Inc. | Ablation catheter assembly with radially decreasing helix and method of use |
| JP4883433B2 (ja) | 1999-05-16 | 2012-02-22 | 株式会社ワイエス・メディカル | バルーンカテーテルおよびその製造方法並びにカテーテルチューブへのバルーンの装着方法 |
| US6283959B1 (en) | 1999-08-23 | 2001-09-04 | Cyrocath Technologies, Inc. | Endovascular cryotreatment catheter |
| US7510536B2 (en) | 1999-09-17 | 2009-03-31 | University Of Washington | Ultrasound guided high intensity focused ultrasound treatment of nerves |
| US20070265563A1 (en) | 2006-05-11 | 2007-11-15 | Heuser Richard R | Device for treating chronic total occlusion |
| JP2003513691A (ja) | 1999-10-25 | 2003-04-15 | シーラス、コーポレイション | 血管を封止するための集束超音波の使用 |
| US6542781B1 (en) | 1999-11-22 | 2003-04-01 | Scimed Life Systems, Inc. | Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue |
| US6745080B2 (en) | 1999-11-22 | 2004-06-01 | Scimed Life Systems, Inc. | Helical and pre-oriented loop structures for supporting diagnostic and therapeutic elements in contact with body tissue |
| US6529756B1 (en) | 1999-11-22 | 2003-03-04 | Scimed Life Systems, Inc. | Apparatus for mapping and coagulating soft tissue in or around body orifices |
| US6626855B1 (en) | 1999-11-26 | 2003-09-30 | Therus Corpoation | Controlled high efficiency lesion formation using high intensity ultrasound |
| US6575932B1 (en) | 1999-12-02 | 2003-06-10 | Ottawa Heart Institute | Adjustable multi-balloon local delivery device |
| US6885888B2 (en) | 2000-01-20 | 2005-04-26 | The Cleveland Clinic Foundation | Electrical stimulation of the sympathetic nerve chain |
| ATE524130T1 (de) | 2000-02-03 | 2011-09-15 | Baylor College Medicine | Intraossalnervablationssystem |
| US6551274B2 (en) | 2000-02-29 | 2003-04-22 | Biosense Webster, Inc. | Cryoablation catheter with an expandable cooling chamber |
| ATE413848T1 (de) | 2000-05-12 | 2008-11-15 | Cardima Inc | Mehrkanaliges hochfrequenzabgabesystem mit koagulierungsreduktion |
| EP1286624B1 (en) | 2000-05-16 | 2008-07-09 | Atrionix, Inc. | Deflectable tip catheter with guidewire tracking mechanism |
| US6511500B1 (en) | 2000-06-06 | 2003-01-28 | Marc Mounir Rahme | Use of autonomic nervous system neurotransmitters inhibition and atrial parasympathetic fibers ablation for the treatment of atrial arrhythmias and to preserve drug effects |
| US6511478B1 (en) | 2000-06-30 | 2003-01-28 | Scimed Life Systems, Inc. | Medical probe with reduced number of temperature sensor wires |
| GB2365127A (en) | 2000-07-20 | 2002-02-13 | Jomed Imaging Ltd | Catheter |
| CA2416581A1 (en) | 2000-07-25 | 2002-04-25 | Rita Medical Systems, Inc. | Apparatus for detecting and treating tumors using localized impedance measurement |
| JP2002078809A (ja) | 2000-09-07 | 2002-03-19 | Shutaro Satake | 肺静脈電気的隔離用バルーンカテーテル |
| US7387628B1 (en) | 2000-09-15 | 2008-06-17 | Boston Scientific Scimed, Inc. | Methods and systems for focused bipolar tissue ablation |
| US7616997B2 (en) | 2000-09-27 | 2009-11-10 | Kieval Robert S | Devices and methods for cardiovascular reflex control via coupled electrodes |
| US6845267B2 (en) | 2000-09-28 | 2005-01-18 | Advanced Bionics Corporation | Systems and methods for modulation of circulatory perfusion by electrical and/or drug stimulation |
| US6926669B1 (en) | 2000-10-10 | 2005-08-09 | Medtronic, Inc. | Heart wall ablation/mapping catheter and method |
| US20030149368A1 (en) | 2000-10-24 | 2003-08-07 | Hennemann Willard W. | Method and apparatus for locating and detecting vascular plaque via impedence and conductivity measurements, and for cryogenically passivating vascular plaque and inhibiting vascular plaque progression and rupture |
| US20040087936A1 (en) | 2000-11-16 | 2004-05-06 | Barrx, Inc. | System and method for treating abnormal tissue in an organ having a layered tissue structure |
| US6832114B1 (en) | 2000-11-21 | 2004-12-14 | Advanced Bionics Corporation | Systems and methods for modulation of pancreatic endocrine secretion and treatment of diabetes |
| US6728563B2 (en) | 2000-11-29 | 2004-04-27 | St. Jude Medical, Daig Division, Inc. | Electrophysiology/ablation catheter having “halo” configuration |
| US6666862B2 (en) | 2001-03-01 | 2003-12-23 | Cardiac Pacemakers, Inc. | Radio frequency ablation system and method linking energy delivery with fluid flow |
| AU2002250250A1 (en) * | 2001-03-01 | 2002-09-19 | Three Arch Partners | Intravascular device for treatment of hypertension |
| US20020147480A1 (en) | 2001-04-04 | 2002-10-10 | Mamayek Donald S. | Treatment of lipid pool |
| US6666858B2 (en) | 2001-04-12 | 2003-12-23 | Scimed Life Systems, Inc. | Cryo balloon for atrial ablation |
| US8123789B2 (en) | 2002-04-29 | 2012-02-28 | Rohit Khanna | Central nervous system cooling catheter |
| US6972016B2 (en) | 2001-05-01 | 2005-12-06 | Cardima, Inc. | Helically shaped electrophysiology catheter |
| US20090118780A1 (en) | 2001-07-23 | 2009-05-07 | Dilorenzo Daniel John | Method and apparatus for conformal electrodes for autonomic neuromodulation for the treatment of obesity and other conditions |
| US20060167498A1 (en) | 2001-07-23 | 2006-07-27 | Dilorenzo Daniel J | Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of disease |
| US20060116736A1 (en) | 2001-07-23 | 2006-06-01 | Dilorenzo Daniel J | Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of obesity |
| DE60203806T2 (de) | 2001-08-31 | 2005-10-06 | Boston Scientific Ltd., St. Michael | Perkutane pringle-okklusionsvorrichtung |
| US6979342B2 (en) | 2001-09-19 | 2005-12-27 | Advanced Cardiovascular Systems, Incc | Catheter with a polyimide distal tip |
| US20030060813A1 (en) | 2001-09-22 | 2003-03-27 | Loeb Marvin P. | Devices and methods for safely shrinking tissues surrounding a duct, hollow organ or body cavity |
| JP2005503241A (ja) | 2001-09-27 | 2005-02-03 | ガリル メディカル リミテッド | クライオプラスティ装置および方法 |
| JP3607231B2 (ja) | 2001-09-28 | 2005-01-05 | 有限会社日本エレクテル | 高周波加温バルーンカテーテル |
| US8974446B2 (en) | 2001-10-11 | 2015-03-10 | St. Jude Medical, Inc. | Ultrasound ablation apparatus with discrete staggered ablation zones |
| US7517349B2 (en) | 2001-10-22 | 2009-04-14 | Vnus Medical Technologies, Inc. | Electrosurgical instrument and method |
| US20030088240A1 (en) | 2001-11-02 | 2003-05-08 | Vahid Saadat | Methods and apparatus for cryo-therapy |
| US7819826B2 (en) | 2002-01-23 | 2010-10-26 | The Regents Of The University Of California | Implantable thermal treatment method and apparatus |
| US7155284B1 (en) | 2002-01-24 | 2006-12-26 | Advanced Bionics Corporation | Treatment of hypertension |
| US20030235609A1 (en) | 2002-01-25 | 2003-12-25 | Lautt Wilfred Wayne | Use of cholinesterase antagonists to treat insulin resistance |
| US7477945B2 (en) | 2002-02-01 | 2009-01-13 | The Cleveland Clinic Foundation | Delivery device for stimulating the sympathetic nerve chain |
| AU2003216133A1 (en) | 2002-02-01 | 2003-09-02 | The Cleveland Clinic Foundation | Neural stimulation delivery device with independently moveable delivery structures |
| ITBS20020039U1 (it) | 2002-03-20 | 2003-09-22 | Fogazzi Di Venturelli Andrea & | Catetere con elettrodo flessibile raffreddato |
| US7937145B2 (en) | 2002-03-22 | 2011-05-03 | Advanced Neuromodulation Systems, Inc. | Dynamic nerve stimulation employing frequency modulation |
| US7239912B2 (en) | 2002-03-22 | 2007-07-03 | Leptos Biomedical, Inc. | Electric modulation of sympathetic nervous system |
| US7702386B2 (en) | 2002-03-22 | 2010-04-20 | Leptos Biomedical, Inc. | Nerve stimulation for treatment of obesity, metabolic syndrome, and Type 2 diabetes |
| US7689276B2 (en) | 2002-09-13 | 2010-03-30 | Leptos Biomedical, Inc. | Dynamic nerve stimulation for treatment of disorders |
| US7689277B2 (en) | 2002-03-22 | 2010-03-30 | Leptos Biomedical, Inc. | Neural stimulation for treatment of metabolic syndrome and type 2 diabetes |
| US8551069B2 (en) | 2002-04-08 | 2013-10-08 | Medtronic Adrian Luxembourg S.a.r.l. | Methods and apparatus for treating contrast nephropathy |
| US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US8131371B2 (en) | 2002-04-08 | 2012-03-06 | Ardian, Inc. | Methods and apparatus for monopolar renal neuromodulation |
| US7756583B2 (en) | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
| US20070129761A1 (en) | 2002-04-08 | 2007-06-07 | Ardian, Inc. | Methods for treating heart arrhythmia |
| US7853333B2 (en) | 2002-04-08 | 2010-12-14 | Ardian, Inc. | Methods and apparatus for multi-vessel renal neuromodulation |
| US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
| US6978174B2 (en) | 2002-04-08 | 2005-12-20 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US8145317B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods for renal neuromodulation |
| US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
| US7162303B2 (en) | 2002-04-08 | 2007-01-09 | Ardian, Inc. | Renal nerve stimulation method and apparatus for treatment of patients |
| US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
| US8145316B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US20070135875A1 (en) | 2002-04-08 | 2007-06-14 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US7620451B2 (en) | 2005-12-29 | 2009-11-17 | Ardian, Inc. | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach |
| US20110207758A1 (en) | 2003-04-08 | 2011-08-25 | Medtronic Vascular, Inc. | Methods for Therapeutic Renal Denervation |
| US6730078B2 (en) | 2002-04-22 | 2004-05-04 | Cardiac Pacemakers, Inc. | RF ablation apparatus and method using multi-frequency energy delivery |
| US6887236B2 (en) | 2002-05-03 | 2005-05-03 | Pinhas Gilboa | Multiple-electrode catheter assembly and method of operating such a catheter assembly |
| US7144407B1 (en) | 2002-05-30 | 2006-12-05 | Alsius Corporation | Cardiovascular intra aortic balloon pump catheter with heat exchange function and methods of use |
| US7181288B1 (en) * | 2002-06-24 | 2007-02-20 | The Cleveland Clinic Foundation | Neuromodulation device and method of using the same |
| US20130197555A1 (en) | 2002-07-01 | 2013-08-01 | Recor Medical, Inc. | Intraluminal devices and methods for denervation |
| US20040082859A1 (en) | 2002-07-01 | 2004-04-29 | Alan Schaer | Method and apparatus employing ultrasound energy to treat body sphincters |
| US8361067B2 (en) | 2002-09-30 | 2013-01-29 | Relievant Medsystems, Inc. | Methods of therapeutically heating a vertebral body to treat back pain |
| AU2003284018A1 (en) | 2002-10-04 | 2004-05-04 | Microchips, Inc. | Medical device for neural stimulation and controlled drug delivery |
| US20040082947A1 (en) | 2002-10-25 | 2004-04-29 | The Regents Of The University Of Michigan | Ablation catheters |
| US20050033137A1 (en) | 2002-10-25 | 2005-02-10 | The Regents Of The University Of Michigan | Ablation catheters and methods for their use |
| US20060241366A1 (en) | 2002-10-31 | 2006-10-26 | Gary Falwell | Electrophysiology loop catheter |
| US6893433B2 (en) | 2002-12-11 | 2005-05-17 | Cryocor, Inc. | System and method for performing a single step cryoablation |
| US7195625B2 (en) | 2002-12-11 | 2007-03-27 | Cryocor, Inc. | Catheter system for performing a single step cryoablation |
| US6796979B2 (en) | 2002-12-11 | 2004-09-28 | Cryocor, Inc. | Coaxial catheter system for performing a single step cryoablation |
| US7004961B2 (en) | 2003-01-09 | 2006-02-28 | Edward Wong | Medical device and method for temperature control and treatment of the brain and spinal cord |
| JP4067976B2 (ja) | 2003-01-24 | 2008-03-26 | 有限会社日本エレクテル | 高周波加温バルーンカテーテル |
| US7013169B2 (en) | 2003-01-27 | 2006-03-14 | Cardiac Pacemakers, Inc. | Dual steer preshaped catheter |
| US20050015048A1 (en) | 2003-03-12 | 2005-01-20 | Chiu Jessica G. | Infusion treatment agents, catheters, filter devices, and occlusion devices, and use thereof |
| US7758623B2 (en) | 2003-03-17 | 2010-07-20 | The Board Of Trustees Of The Leland Stanford Junior University | Transesophageal heat exchange catheter for cooling of the heart |
| CA2519636A1 (en) | 2003-03-27 | 2004-10-14 | Cierra, Inc. | Methods and apparatus for treatment of patent foramen ovale |
| US7938828B2 (en) | 2003-03-28 | 2011-05-10 | Boston Scientific Scimed, Inc. | Cooled ablation catheter |
| US20040254572A1 (en) | 2003-04-25 | 2004-12-16 | Mcintyre Jon T. | Self anchoring radio frequency ablation array |
| US7738952B2 (en) | 2003-06-09 | 2010-06-15 | Palo Alto Investors | Treatment of conditions through modulation of the autonomic nervous system |
| US7149574B2 (en) | 2003-06-09 | 2006-12-12 | Palo Alto Investors | Treatment of conditions through electrical modulation of the autonomic nervous system |
| US7101362B2 (en) | 2003-07-02 | 2006-09-05 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Steerable and shapable catheter employing fluid force |
| US20070060971A1 (en) | 2003-07-21 | 2007-03-15 | Ofer Glasberg | Hepatic device for treatment or glucose detection |
| US20050033136A1 (en) | 2003-08-01 | 2005-02-10 | Assaf Govari | Catheter with electrode strip |
| US7569052B2 (en) | 2003-09-12 | 2009-08-04 | Boston Scientific Scimed, Inc. | Ablation catheter with tissue protecting assembly |
| EP1667595B1 (en) | 2003-09-12 | 2014-01-01 | Vessix Vascular, Inc. | System for selectable eccentric remodeling and/or ablation of atherosclerotic material |
| US7416549B2 (en) | 2003-10-10 | 2008-08-26 | Boston Scientific Scimed, Inc. | Multi-zone bipolar ablation probe assembly |
| CN1901845B (zh) | 2003-10-20 | 2010-09-29 | 约翰·霍普金斯大学 | 消融心房组织的导管 |
| US20110040171A1 (en) | 2003-12-16 | 2011-02-17 | University Of Washington | Image guided high intensity focused ultrasound treatment of nerves |
| US7150745B2 (en) | 2004-01-09 | 2006-12-19 | Barrx Medical, Inc. | Devices and methods for treatment of luminal tissue |
| US7819870B2 (en) | 2005-10-13 | 2010-10-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Tissue contact and thermal assessment for brush electrodes |
| US7371231B2 (en) | 2004-02-02 | 2008-05-13 | Boston Scientific Scimed, Inc. | System and method for performing ablation using a balloon |
| US7727228B2 (en) | 2004-03-23 | 2010-06-01 | Medtronic Cryocath Lp | Method and apparatus for inflating and deflating balloon catheters |
| US8343031B2 (en) | 2004-03-23 | 2013-01-01 | Michael Gertner | Obesity treatment systems |
| US7854733B2 (en) | 2004-03-24 | 2010-12-21 | Biosense Webster, Inc. | Phased-array for tissue treatment |
| WO2006007048A2 (en) | 2004-05-04 | 2006-01-19 | The Cleveland Clinic Foundation | Methods of treating medical conditions by neuromodulation of the sympathetic nervous system |
| WO2005107859A1 (en) | 2004-05-04 | 2005-11-17 | The Cleveland Clinic Foundation | Methods of treating medical conditions by neuromodulation of the cerebellar pathways |
| EP1761187B1 (en) | 2004-05-17 | 2011-11-30 | C.R. Bard, Inc. | Irrigated catheter |
| RU2277381C2 (ru) | 2004-06-28 | 2006-06-10 | ГОУ ВПО КемГМА Министерства Здравоохранения Российской Федерации | Способ хирургического лечения сахарного диабета |
| WO2006002635A1 (en) | 2004-06-30 | 2006-01-12 | Gregersen Enterprises Aps | Morphometry of a bodily hollow system |
| US20060047326A1 (en) | 2004-08-27 | 2006-03-02 | James Wheeler | Application of specific neuromodulation waveforms to reduce symptoms of neurological disorders |
| US7337006B2 (en) | 2004-09-08 | 2008-02-26 | Spinal Modulation, Inc. | Methods and systems for modulating neural tissue |
| EP1804907A2 (en) | 2004-09-10 | 2007-07-11 | The Cleveland Clinic Foundation | Methods and systems of achieving hemodynamic control through neuromodulation |
| US8396548B2 (en) | 2008-11-14 | 2013-03-12 | Vessix Vascular, Inc. | Selective drug delivery in a lumen |
| US9713730B2 (en) | 2004-09-10 | 2017-07-25 | Boston Scientific Scimed, Inc. | Apparatus and method for treatment of in-stent restenosis |
| US10973570B2 (en) | 2004-09-10 | 2021-04-13 | Boston Scientific Scimed, Inc. | Apparatus and method for treatment of in-stent restenosis |
| DE202005022062U1 (de) | 2004-10-06 | 2012-12-18 | Guided Therapy Systems, Llc | System zur Ultraschallgewebebehandlung |
| US20060089637A1 (en) | 2004-10-14 | 2006-04-27 | Werneth Randell L | Ablation catheter |
| US7524318B2 (en) | 2004-10-28 | 2009-04-28 | Boston Scientific Scimed, Inc. | Ablation probe with flared electrodes |
| US20070083239A1 (en) | 2005-09-23 | 2007-04-12 | Denise Demarais | Methods and apparatus for inducing, monitoring and controlling renal neuromodulation |
| US7937143B2 (en) | 2004-11-02 | 2011-05-03 | Ardian, Inc. | Methods and apparatus for inducing controlled renal neuromodulation |
| US7949407B2 (en) | 2004-11-05 | 2011-05-24 | Asthmatx, Inc. | Energy delivery devices and methods |
| US20070093802A1 (en) | 2005-10-21 | 2007-04-26 | Danek Christopher J | Energy delivery devices and methods |
| US20060111704A1 (en) | 2004-11-22 | 2006-05-25 | Rox Medical, Inc. | Devices, systems, and methods for energy assisted arterio-venous fistula creation |
| US20060135953A1 (en) | 2004-12-22 | 2006-06-22 | Wlodzimierz Kania | Tissue ablation system including guidewire with sensing element |
| US8066702B2 (en) | 2005-01-11 | 2011-11-29 | Rittman Iii William J | Combination electrical stimulating and infusion medical device and method |
| WO2006092000A1 (en) | 2005-03-02 | 2006-09-08 | Cathrx Ltd | A heat treatment catheter |
| US8075498B2 (en) | 2005-03-04 | 2011-12-13 | Endosense Sa | Medical apparatus system having optical fiber load sensing capability |
| US8182433B2 (en) | 2005-03-04 | 2012-05-22 | Endosense Sa | Medical apparatus system having optical fiber load sensing capability |
| US7674256B2 (en) | 2005-03-17 | 2010-03-09 | Boston Scientific Scimed, Inc. | Treating internal body tissue |
| US7670337B2 (en) | 2005-03-25 | 2010-03-02 | Boston Scientific Scimed, Inc. | Ablation probe having a plurality of arrays of electrodes |
| ES2380487T3 (es) | 2005-03-28 | 2012-05-14 | Vessix Vascular, Inc. | Caracterización de tejido eléctrico intraluminal y energía RF ajustada para el tratamiento selectivo de ateroma y de otros tejidos diana |
| US7963287B2 (en) | 2005-04-28 | 2011-06-21 | Boston Scientific Scimed, Inc. | Tissue-treatment methods |
| CN101309651B (zh) | 2005-06-20 | 2011-12-07 | 麦德托尼克消融前沿有限公司 | 消融导管 |
| ES2670822T3 (es) | 2005-06-29 | 2018-06-01 | Zoll Circulation, Inc. | Dispositivos y sistemas para el enfriamiento endovascular rápido |
| US20070016274A1 (en) | 2005-06-29 | 2007-01-18 | Boveja Birinder R | Gastrointestinal (GI) ablation for GI tumors or to provide therapy for obesity, motility disorders, G.E.R.D., or to induce weight loss |
| AU2006268238A1 (en) | 2005-07-11 | 2007-01-18 | Medtronic Ablation Frontiers Llc | Low power tissue ablation system |
| US7794458B2 (en) | 2005-07-22 | 2010-09-14 | Boston Scientific Scimed, Inc. | Bipolar radio frequency ablation device with retractable insulator |
| US20070021803A1 (en) | 2005-07-22 | 2007-01-25 | The Foundry Inc. | Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction |
| US20070027484A1 (en) * | 2005-07-28 | 2007-02-01 | Cyberonics, Inc. | Autonomic nerve stimulation to treat a pancreatic disorder |
| US8894589B2 (en) | 2005-08-01 | 2014-11-25 | Endosense Sa | Medical apparatus system having optical fiber load sensing capability |
| US20070142879A1 (en) | 2005-12-20 | 2007-06-21 | The Cleveland Clinic Foundation | Apparatus and method for modulating the baroreflex system |
| US8672936B2 (en) | 2005-10-13 | 2014-03-18 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Systems and methods for assessing tissue contact |
| US8679109B2 (en) | 2005-10-13 | 2014-03-25 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Dynamic contact assessment for electrode catheters |
| US8167805B2 (en) | 2005-10-20 | 2012-05-01 | Kona Medical, Inc. | Systems and methods for ultrasound applicator station keeping |
| US8162935B2 (en) | 2005-10-27 | 2012-04-24 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Systems and methods for electrode contact assessment |
| US8182444B2 (en) | 2005-11-04 | 2012-05-22 | Medrad, Inc. | Delivery of agents such as cells to tissue |
| NL1030361C2 (nl) | 2005-11-07 | 2007-05-08 | Keltec B V | Afgifte-eenheid met verbeterde luchttoevoer. |
| US8406866B2 (en) | 2005-12-06 | 2013-03-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System and method for assessing coupling between an electrode and tissue |
| US8449535B2 (en) | 2005-12-06 | 2013-05-28 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System and method for assessing coupling between an electrode and tissue |
| US8317783B2 (en) | 2005-12-06 | 2012-11-27 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Assessment of electrode coupling for tissue ablation |
| US10362959B2 (en) | 2005-12-06 | 2019-07-30 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System and method for assessing the proximity of an electrode to tissue in a body |
| US9254163B2 (en) | 2005-12-06 | 2016-02-09 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Assessment of electrode coupling for tissue ablation |
| US8267926B2 (en) | 2005-12-06 | 2012-09-18 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Assessment of electrode coupling for tissue ablation |
| US8403925B2 (en) | 2006-12-06 | 2013-03-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System and method for assessing lesions in tissue |
| US8137342B2 (en) | 2005-12-24 | 2012-03-20 | Crossman Arthur W | Circumferential ablation guide wire system and related method of using the same |
| US8377056B2 (en) | 2005-12-29 | 2013-02-19 | Boston Scientific Scimed, Inc. | Method of treating tissue with radio frequency vascular electrode array |
| CN100488581C (zh) | 2005-12-31 | 2009-05-20 | 南京医科大学 | 芯片植入式闭环血压调控方法与系统 |
| WO2007082381A1 (en) | 2006-01-20 | 2007-07-26 | Diamedica Inc. | Compositions containing (s)-bethanechol and their use in the treatment of insulin resistance, type 2 diabetes, glucose intolerance and related disorders |
| US9119651B2 (en) | 2006-02-13 | 2015-09-01 | Retro Vascular, Inc. | Recanalizing occluded vessels using controlled antegrade and retrograde tracking |
| CA2642568C (en) | 2006-02-22 | 2015-11-24 | Custom Medical Applications, Inc. | Ablation instruments and related methods |
| US20080183237A1 (en) * | 2006-04-18 | 2008-07-31 | Electrocore, Inc. | Methods And Apparatus For Treating Ileus Condition Using Electrical Signals |
| WO2007124458A2 (en) | 2006-04-20 | 2007-11-01 | The Regents Of The University Of California | Method of thermal treatment for myolysis and destruction of benign uterine tumors |
| US8295926B2 (en) | 2006-06-02 | 2012-10-23 | Advanced Neuromodulation Systems, Inc. | Dynamic nerve stimulation in combination with other eating disorder treatment modalities |
| US8048063B2 (en) | 2006-06-09 | 2011-11-01 | Endosense Sa | Catheter having tri-axial force sensor |
| US8567265B2 (en) | 2006-06-09 | 2013-10-29 | Endosense, SA | Triaxial fiber optic force sensing catheter |
| US20070287994A1 (en) | 2006-06-12 | 2007-12-13 | Pankaj Amrit Patel | Endoscopically Introducible Expandable Bipolar Probe |
| US7769469B2 (en) | 2006-06-26 | 2010-08-03 | Meridian Medical Systems, Llc | Integrated heating/sensing catheter apparatus for minimally invasive applications |
| WO2008002654A2 (en) | 2006-06-28 | 2008-01-03 | C.R. Bard, Inc. | Methods and apparatus for assessing and improving electrode contact with cardiac tissue |
| ES2378956T5 (es) | 2006-06-28 | 2019-10-09 | Medtronic Ardian Luxembourg | Sistemas para la neuromodulación renal térmicamente inducida |
| WO2008045877A2 (en) | 2006-10-10 | 2008-04-17 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Electrode tip and ablation system |
| EP2455035B1 (en) | 2006-10-18 | 2015-11-25 | Vessix Vascular, Inc. | Inducing desirable temperature effects on body tissue |
| EP2455036B1 (en) | 2006-10-18 | 2015-07-15 | Vessix Vascular, Inc. | Tuned RF energy and electrical tissue characterization for selective treatment of target tissues |
| ES2407329T3 (es) | 2006-10-18 | 2013-06-12 | Vessix Vascular, Inc. | Sistema para inducir efectos de temperatura deseables sobre un tejido corporal |
| US7931647B2 (en) | 2006-10-20 | 2011-04-26 | Asthmatx, Inc. | Method of delivering energy to a lung airway using markers |
| US20080140074A1 (en) | 2006-12-07 | 2008-06-12 | Cierra, Inc. | Multi-electrode apparatus for tissue welding and ablation |
| US7951143B2 (en) | 2006-12-28 | 2011-05-31 | St. Jude Medical, Artial Fibrillation Divsion, Inc. | Cooled ablation catheter with reciprocating flow |
| US7591816B2 (en) | 2006-12-28 | 2009-09-22 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Irrigated ablation catheter having a pressure sensor to detect tissue contact |
| US8265745B2 (en) | 2006-12-29 | 2012-09-11 | St. Jude Medical, Atrial Fibillation Division, Inc. | Contact sensor and sheath exit sensor |
| US8226648B2 (en) | 2007-12-31 | 2012-07-24 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Pressure-sensitive flexible polymer bipolar electrode |
| US7917230B2 (en) | 2007-01-30 | 2011-03-29 | Cardiac Pacemakers, Inc. | Neurostimulating lead having a stent-like anchor |
| US9037244B2 (en) | 2007-02-13 | 2015-05-19 | Virender K. Sharma | Method and apparatus for electrical stimulation of the pancreatico-biliary system |
| US8226602B2 (en) | 2007-03-30 | 2012-07-24 | Reshape Medical, Inc. | Intragastric balloon system and therapeutic processes and products |
| US8764742B2 (en) | 2007-04-04 | 2014-07-01 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Irrigated catheter |
| US8979837B2 (en) | 2007-04-04 | 2015-03-17 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Flexible tip catheter with extended fluid lumen |
| WO2008128070A2 (en) | 2007-04-11 | 2008-10-23 | The Cleveland Clinic Foundation | Method and apparatus for renal neuromodulation |
| US20100211059A1 (en) * | 2007-04-19 | 2010-08-19 | Deem Mark E | Systems and methods for creating an effect using microwave energy to specified tissue |
| US8577447B2 (en) | 2007-05-01 | 2013-11-05 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Optic-based contact sensing assembly and system |
| US9855410B2 (en) | 2007-05-01 | 2018-01-02 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Optic-based contact sensing assembly and system |
| US8641711B2 (en) | 2007-05-04 | 2014-02-04 | Covidien Lp | Method and apparatus for gastrointestinal tract ablation for treatment of obesity |
| US8588885B2 (en) | 2007-05-09 | 2013-11-19 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Bendable catheter arms having varied flexibility |
| WO2008141150A2 (en) | 2007-05-09 | 2008-11-20 | Irvine Biomedical, Inc. | Basket catheter having multiple electrodes |
| US8641704B2 (en) | 2007-05-11 | 2014-02-04 | Medtronic Ablation Frontiers Llc | Ablation therapy system and method for treating continuous atrial fibrillation |
| US10220187B2 (en) | 2010-06-16 | 2019-03-05 | St. Jude Medical, Llc | Ablation catheter having flexible tip with multiple flexible electrode segments |
| US11395694B2 (en) | 2009-05-07 | 2022-07-26 | St. Jude Medical, Llc | Irrigated ablation catheter with multiple segmented ablation electrodes |
| US8983609B2 (en) | 2007-05-30 | 2015-03-17 | The Cleveland Clinic Foundation | Apparatus and method for treating pulmonary conditions |
| US8160690B2 (en) | 2007-06-14 | 2012-04-17 | Hansen Medical, Inc. | System and method for determining electrode-tissue contact based on amplitude modulation of sensed signal |
| US7881784B2 (en) | 2007-06-14 | 2011-02-01 | The Board Of Regents Of The University Of Texas System | Hepatic electrical stimulation |
| US20100191151A1 (en) | 2007-06-15 | 2010-07-29 | Taewoong Medical Co., Ltd. | Bipolar electrode type guide wire and catheter system |
| US20100049289A1 (en) | 2007-07-10 | 2010-02-25 | Ams Research Corporation | Tissue anchor |
| US20090118777A1 (en) | 2007-08-09 | 2009-05-07 | Kobi Iki | Efferent and afferent splanchnic nerve stimulation |
| US8725673B2 (en) | 2007-08-22 | 2014-05-13 | Linkedin Corporation | Evaluating an item based on user reputation information |
| WO2009029614A1 (en) | 2007-08-27 | 2009-03-05 | The Feinstein Institute For Medical Research | Devices and methods for inhibiting granulocyte activation by neural stimulation |
| WO2009061969A2 (en) * | 2007-11-06 | 2009-05-14 | Daniel Gelbart | In vivo inflatable structures, for example to expand stents |
| US8906011B2 (en) | 2007-11-16 | 2014-12-09 | Kardium Inc. | Medical device for use in bodily lumens, for example an atrium |
| WO2009076461A1 (en) | 2007-12-10 | 2009-06-18 | Ablation Frontiers, Inc. | Rf energy delivery system and method |
| US8155744B2 (en) | 2007-12-13 | 2012-04-10 | The Cleveland Clinic Foundation | Neuromodulatory methods for treating pulmonary disorders |
| US8211102B2 (en) | 2007-12-21 | 2012-07-03 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Contact sensing flexible conductive polymer electrode |
| US8226641B2 (en) * | 2007-12-21 | 2012-07-24 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Medical catheter with deflection pull ring and distal tip attachment apparatus |
| WO2009086418A1 (en) | 2007-12-28 | 2009-07-09 | Boston Scientific Scimed, Inc. | Electrosurgical probe having conductive outer surface to initiate ablation between electrodes |
| EP2080483B1 (de) | 2008-01-17 | 2013-06-05 | Biotronik CRM Patent AG | Ablationskatheter-Anordnung und Kühlungssteuerung |
| WO2009090440A1 (en) * | 2008-01-18 | 2009-07-23 | Tivi Kft | System for the treatment of diabetes |
| US20090247933A1 (en) | 2008-03-27 | 2009-10-01 | The Regents Of The University Of California; Angiodynamics, Inc. | Balloon catheter method for reducing restenosis via irreversible electroporation |
| CN105031811B (zh) | 2008-04-04 | 2017-09-08 | 安特罗麦迪克斯公司 | 用于葡萄糖调节的方法和系统 |
| EP2211978A1 (en) | 2008-04-30 | 2010-08-04 | Medtronic, Inc. | Techniques for placing medical leads for electrical stimulation of nerve tissue |
| US20090275997A1 (en) | 2008-05-01 | 2009-11-05 | Michael Allen Faltys | Vagus nerve stimulation electrodes and methods of use |
| EP2662046B1 (en) * | 2008-05-09 | 2023-03-15 | Nuvaira, Inc. | Systems and assemblies for treating a bronchial tree |
| US8042251B2 (en) | 2008-05-21 | 2011-10-25 | Boston Scientific Scimed, Inc. | Systems and methods for heating and cooling during stent crimping |
| US8128617B2 (en) * | 2008-05-27 | 2012-03-06 | Boston Scientific Scimed, Inc. | Electrical mapping and cryo ablating with a balloon catheter |
| CA3206234A1 (en) | 2008-06-06 | 2009-12-10 | Ulthera, Inc. | A system and method for cosmetic treatment and imaging |
| US8002642B2 (en) | 2008-06-09 | 2011-08-23 | Indian Industries, Inc. | Playset system components |
| US8882761B2 (en) | 2008-07-15 | 2014-11-11 | Catheffects, Inc. | Catheter and method for improved ablation |
| US9700366B2 (en) | 2008-08-01 | 2017-07-11 | Covidien Lp | Polyphase electrosurgical system and method |
| DE102008048616B4 (de) | 2008-09-23 | 2010-08-05 | Olympus Winter & Ibe Gmbh | Urologischer Ballonkatheter |
| US8097926B2 (en) | 2008-10-07 | 2012-01-17 | Mc10, Inc. | Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy |
| US8894643B2 (en) | 2008-10-10 | 2014-11-25 | Intuitive Surgical Operations, Inc. | Integral electrode placement and connection systems |
| US8414508B2 (en) | 2008-10-30 | 2013-04-09 | Vytronus, Inc. | System and method for delivery of energy to tissue while compensating for collateral tissue |
| ES2615826T3 (es) | 2008-11-11 | 2017-06-08 | Shifamed Holdings, Llc | Conjunto de electrodos de perfil bajo |
| US9795442B2 (en) | 2008-11-11 | 2017-10-24 | Shifamed Holdings, Llc | Ablation catheters |
| US10987494B2 (en) | 2008-11-11 | 2021-04-27 | Covidien Lp | Pleated or folded catheter-mounted balloon |
| EP2355737B1 (en) | 2008-11-17 | 2021-08-11 | Boston Scientific Scimed, Inc. | Selective accumulation of energy without knowledge of tissue topography |
| US9339331B2 (en) | 2008-12-29 | 2016-05-17 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Non-contact electrode basket catheters with irrigation |
| US8712550B2 (en) | 2008-12-30 | 2014-04-29 | Biosense Webster, Inc. | Catheter with multiple electrode assemblies for use at or near tubular regions of the heart |
| US8808345B2 (en) | 2008-12-31 | 2014-08-19 | Medtronic Ardian Luxembourg S.A.R.L. | Handle assemblies for intravascular treatment devices and associated systems and methods |
| US20100168739A1 (en) | 2008-12-31 | 2010-07-01 | Ardian, Inc. | Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation |
| US9320565B2 (en) | 2008-12-31 | 2016-04-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation devices, systems and method for measuring cooling effect of fluid flow |
| US8652129B2 (en) | 2008-12-31 | 2014-02-18 | Medtronic Ardian Luxembourg S.A.R.L. | Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation |
| US20120143279A1 (en) | 2009-03-24 | 2012-06-07 | Leon Ekchian | Methods and kits for treating appetite suppressing disorders and disorders with an increased metabolic rate |
| US20100256629A1 (en) | 2009-04-06 | 2010-10-07 | Voyage Medical, Inc. | Methods and devices for treatment of the ostium |
| US8728068B2 (en) | 2009-04-09 | 2014-05-20 | Urologix, Inc. | Cooled antenna for device insertable into a body |
| US9393068B1 (en) | 2009-05-08 | 2016-07-19 | St. Jude Medical International Holding S.À R.L. | Method for predicting the probability of steam pop in RF ablation therapy |
| CN101947130B (zh) | 2009-05-08 | 2015-02-04 | 圣犹达医疗用品卢森堡控股有限公司 | 用于在基于导管的消融治疗中控制损伤尺寸的方法和装置 |
| US9474565B2 (en) | 2009-09-22 | 2016-10-25 | Mederi Therapeutics, Inc. | Systems and methods for treating tissue with radiofrequency energy |
| US9750563B2 (en) | 2009-09-22 | 2017-09-05 | Mederi Therapeutics, Inc. | Systems and methods for treating tissue with radiofrequency energy |
| US20110092880A1 (en) | 2009-10-12 | 2011-04-21 | Michael Gertner | Energetic modulation of nerves |
| US8295912B2 (en) | 2009-10-12 | 2012-10-23 | Kona Medical, Inc. | Method and system to inhibit a function of a nerve traveling with an artery |
| US11998266B2 (en) | 2009-10-12 | 2024-06-04 | Otsuka Medical Devices Co., Ltd | Intravascular energy delivery |
| US8469904B2 (en) | 2009-10-12 | 2013-06-25 | Kona Medical, Inc. | Energetic modulation of nerves |
| US8986231B2 (en) | 2009-10-12 | 2015-03-24 | Kona Medical, Inc. | Energetic modulation of nerves |
| US9174065B2 (en) | 2009-10-12 | 2015-11-03 | Kona Medical, Inc. | Energetic modulation of nerves |
| EP2488250B1 (en) * | 2009-10-12 | 2015-11-25 | Kona Medical, Inc. | Energetic modulation of nerves |
| US8517962B2 (en) | 2009-10-12 | 2013-08-27 | Kona Medical, Inc. | Energetic modulation of nerves |
| US8986211B2 (en) | 2009-10-12 | 2015-03-24 | Kona Medical, Inc. | Energetic modulation of nerves |
| US20140074076A1 (en) | 2009-10-12 | 2014-03-13 | Kona Medical, Inc. | Non-invasive autonomic nervous system modulation |
| US20110118600A1 (en) | 2009-11-16 | 2011-05-19 | Michael Gertner | External Autonomic Modulation |
| US9119951B2 (en) | 2009-10-12 | 2015-09-01 | Kona Medical, Inc. | Energetic modulation of nerves |
| CA2779135C (en) | 2009-10-27 | 2018-09-04 | Innovative Pulmonary Solutions, Inc. | Delivery devices with coolable energy emitting assemblies |
| KR101988708B1 (ko) | 2009-10-30 | 2019-06-12 | 레코 메디컬, 인코포레이티드 | 경피적 초음파 신장 신경차단술을 통해 고혈압을 치료하기 위한 장치 및 방법 |
| BR112012010199B8 (pt) | 2009-11-05 | 2022-08-23 | Nimbus Concepts Llc | Agulha para inserção em paciente |
| US20170049513A1 (en) | 2009-11-06 | 2017-02-23 | Cosman Medical, Inc. | Multiple electrode generator |
| US20110112400A1 (en) | 2009-11-06 | 2011-05-12 | Ardian, Inc. | High intensity focused ultrasound catheter apparatuses, systems, and methods for renal neuromodulation |
| JP6000851B2 (ja) | 2009-11-11 | 2016-10-05 | ホライラ， インコーポレイテッド | 組織治療および狭窄制御のためのシステム、装置、および方法 |
| BR112012011042A2 (pt) | 2009-11-13 | 2019-09-24 | St Jude Medical | cateter de ablação. |
| US20110144637A1 (en) | 2009-12-11 | 2011-06-16 | Medtronic Cryocath Lp | Vein Occlusion Devices and Methods for Catheter-Based Ablation |
| US20110152857A1 (en) | 2009-12-19 | 2011-06-23 | Frank Ingle | Apparatus and Methods For Electrophysiology Procedures |
| RU2421163C1 (ru) | 2009-12-21 | 2011-06-20 | Государственное образовательное учреждение высшего профессионального образования "Кемеровская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" | Способ хирургического лечения сахарного диабета |
| US9962217B2 (en) | 2009-12-23 | 2018-05-08 | Biosense Webster (Israel) Ltd. | Estimation and mapping of ablation volume |
| US20110263921A1 (en) | 2009-12-31 | 2011-10-27 | Anthony Vrba | Patterned Denervation Therapy for Innervated Renal Vasculature |
| US20110160514A1 (en) | 2009-12-31 | 2011-06-30 | Ethicon Endo-Surgery, Inc. | Electrical ablation devices |
| US20110270238A1 (en) | 2009-12-31 | 2011-11-03 | Raed Rizq | Compliant Cryoballoon Apparatus for Denervating Ostia of the Renal Arteries |
| US20110264116A1 (en) | 2009-12-31 | 2011-10-27 | Gordon Kocur | Compressive Denervation Apparatus for Innervated Renal Vasculature |
| WO2011080731A1 (en) * | 2010-01-03 | 2011-07-07 | Angioslide Ltd. | Corrugated balloon catheter and methods of use thereof |
| EP2525715A4 (en) | 2010-01-19 | 2014-06-04 | Medtronic Ardian Luxembourg S R L | METHODS AND APPARATUS FOR RENAL NEUROMODULATION BY STEREOTACTIC RADIOTHERAPY |
| EP2528649A1 (en) | 2010-01-26 | 2012-12-05 | Michael A. Evans | Methods, devices, and agents for denervation |
| WO2011094379A1 (en) | 2010-01-28 | 2011-08-04 | Cook Medical Technologies Llc | Apparatus and method for destruction of vascular thrombus |
| WO2011101778A1 (en) | 2010-02-19 | 2011-08-25 | Koninklijke Philips Electronics N.V. | Ablation catheter and a method of performing ablation |
| US20110208173A1 (en) | 2010-02-24 | 2011-08-25 | Medtronic Vascular, Inc. | Methods for Treating sleep apnea via renal Denervation |
| US8556891B2 (en) | 2010-03-03 | 2013-10-15 | Medtronic Ablation Frontiers Llc | Variable-output radiofrequency ablation power supply |
| WO2011115682A2 (en) | 2010-03-18 | 2011-09-22 | Weinstock Ronald J | System for diagnosing and treatment of diabetic symptoms |
| UA52875U (uk) | 2010-03-31 | 2010-09-10 | Институт Проблем Криобиологии И Криомедицины Национальной Академии Наук Украины | Спосіб періартеріальної денервації печінкової артерії |
| US20110257562A1 (en) | 2010-04-01 | 2011-10-20 | Alan Schaer | Method and apparatus employing ultrasound energy to remodulate vascular nerves |
| US20110257641A1 (en) | 2010-04-14 | 2011-10-20 | Roger Hastings | Phototherapy for renal denervation |
| US9192790B2 (en) | 2010-04-14 | 2015-11-24 | Boston Scientific Scimed, Inc. | Focused ultrasonic renal denervation |
| JP5760079B2 (ja) * | 2010-04-14 | 2015-08-05 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 腎動脈に除神経療法を送達する装置 |
| EP3175808B1 (en) * | 2010-04-26 | 2019-08-21 | Medtronic Ardian Luxembourg S.à.r.l. | Catheter apparatuses and systems for renal neuromodulation |
| US8870863B2 (en) * | 2010-04-26 | 2014-10-28 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses, systems, and methods for renal neuromodulation |
| CA2798352A1 (en) | 2010-05-05 | 2011-11-10 | Automated Medical Instruments, Inc. | Anchored cardiac ablation catheter |
| CN201642315U (zh) | 2010-05-06 | 2010-11-24 | 北京博莱德光电技术开发有限公司 | 一种射频消融电极 |
| EP2568905A4 (en) | 2010-05-12 | 2017-07-26 | Shifamed Holdings, LLC | Low profile electrode assembly |
| US9655677B2 (en) | 2010-05-12 | 2017-05-23 | Shifamed Holdings, Llc | Ablation catheters including a balloon and electrodes |
| US8473067B2 (en) | 2010-06-11 | 2013-06-25 | Boston Scientific Scimed, Inc. | Renal denervation and stimulation employing wireless vascular energy transfer arrangement |
| US9358020B2 (en) * | 2010-06-25 | 2016-06-07 | Boston Scientific Scimed Inc. | Catheter device for delivery energy to a vein |
| DE102010026210A1 (de) | 2010-07-06 | 2012-01-12 | Wolfgang Seidel | Verfahren und Vorrichtung zur Koagulation von Körpergewebe und/oder von Körpergefäßen |
| US9814408B2 (en) | 2010-07-13 | 2017-11-14 | Diversatek Healthcare, Inc. | Display system for displaying conditions of esophageal mucosa and indications of gastroesophageal reflux disease |
| US9408661B2 (en) | 2010-07-30 | 2016-08-09 | Patrick A. Haverkost | RF electrodes on multiple flexible wires for renal nerve ablation |
| US20120029496A1 (en) | 2010-07-30 | 2012-02-02 | Scott Smith | Renal nerve ablation using mild freezing and microwave energy |
| US9084609B2 (en) | 2010-07-30 | 2015-07-21 | Boston Scientific Scime, Inc. | Spiral balloon catheter for renal nerve ablation |
| US9155589B2 (en) | 2010-07-30 | 2015-10-13 | Boston Scientific Scimed, Inc. | Sequential activation RF electrode set for renal nerve ablation |
| US20120029512A1 (en) | 2010-07-30 | 2012-02-02 | Willard Martin R | Balloon with surface electrodes and integral cooling for renal nerve ablation |
| US9463062B2 (en) | 2010-07-30 | 2016-10-11 | Boston Scientific Scimed, Inc. | Cooled conductive balloon RF catheter for renal nerve ablation |
| US20120029505A1 (en) | 2010-07-30 | 2012-02-02 | Jenson Mark L | Self-Leveling Electrode Sets for Renal Nerve Ablation |
| US9539046B2 (en) | 2010-08-03 | 2017-01-10 | Medtronic Cryocath Lp | Cryogenic medical mapping and treatment device |
| US20120089047A1 (en) | 2010-08-05 | 2012-04-12 | Medtronic Vascular, Inc. | Cryoablation apparatuses, systems, and methods for renal neuromodulation |
| EP2608841B1 (de) * | 2010-08-26 | 2016-12-07 | Acandis GmbH & Co. KG | Elektrode für medizinische anwendungen, system mit einer derartigen elektrode und verfahren zur herstellung einer derartigen elektrode |
| US9220899B2 (en) * | 2010-08-26 | 2015-12-29 | Acandis Gmbh & Co. Kg | Electrode for medical applications, system having an electrode, and method for producing an electrode |
| US20120065554A1 (en) | 2010-09-09 | 2012-03-15 | Michael Pikus | Dual Balloon Ablation Catheter with Vessel Deformation Arrangement for Renal Nerve Ablation |
| US20120065506A1 (en) * | 2010-09-10 | 2012-03-15 | Scott Smith | Mechanical, Electromechanical, and/or Elastographic Assessment for Renal Nerve Ablation |
| WO2012052920A1 (en) | 2010-10-18 | 2012-04-26 | CardioSonic Ltd. | Therapeutics reservoir |
| TW201221165A (en) * | 2010-10-20 | 2012-06-01 | Medtronic Ardian Luxembourg | Catheter apparatuses having expandable mesh structures for renal neuromodulation and associated systems and methods |
| US9084610B2 (en) | 2010-10-21 | 2015-07-21 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses, systems, and methods for renal neuromodulation |
| TW201223583A (en) | 2010-10-25 | 2012-06-16 | Medtronic Ardian Luxembourg | Catheter apparatuses having multi-electrode arrays for renal neuromodulation and associated systems and methods |
| CN106377312B (zh) | 2010-10-25 | 2019-12-10 | 美敦力Af卢森堡有限责任公司 | 用于肾神经调节的微波导管设备、系统和方法 |
| TWI513451B (zh) | 2010-10-25 | 2015-12-21 | 美敦力阿迪恩盧森堡公司 | 用於神經調節治療之估算及反饋的裝置、系統及方法 |
| US9060754B2 (en) | 2010-10-26 | 2015-06-23 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation cryotherapeutic devices and associated systems and methods |
| US8945107B2 (en) | 2010-10-26 | 2015-02-03 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation cryotherapeutic devices and associated systems and methods |
| US9220558B2 (en) | 2010-10-27 | 2015-12-29 | Boston Scientific Scimed, Inc. | RF renal denervation catheter with multiple independent electrodes |
| US9572508B2 (en) | 2010-11-09 | 2017-02-21 | St. Jude Medical, Atrial Fibrillation Division, Inc. | In-plane dual loop fixed diameter electrophysiology catheters and methods of manufacturing therefor |
| US9028485B2 (en) | 2010-11-15 | 2015-05-12 | Boston Scientific Scimed, Inc. | Self-expanding cooling electrode for renal nerve ablation |
| US20120123276A1 (en) | 2010-11-16 | 2012-05-17 | Assaf Govari | Catheter with optical contact sensing |
| WO2012068471A1 (en) * | 2010-11-19 | 2012-05-24 | Boston Scientific Scimed, Inc. | Renal nerve detection and ablation apparatus and method |
| US9192435B2 (en) * | 2010-11-22 | 2015-11-24 | Boston Scientific Scimed, Inc. | Renal denervation catheter with cooled RF electrode |
| US9532828B2 (en) | 2010-11-29 | 2017-01-03 | Medtronic Ablation Frontiers Llc | System and method for adaptive RF ablation |
| US20120157992A1 (en) | 2010-12-15 | 2012-06-21 | Scott Smith | Off-wall electrode device for renal nerve ablation |
| US8560086B2 (en) | 2010-12-02 | 2013-10-15 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Catheter electrode assemblies and methods of construction therefor |
| US11246653B2 (en) | 2010-12-07 | 2022-02-15 | Boaz Avitall | Catheter systems for cardiac arrhythmia ablation |
| DK2651431T3 (en) | 2010-12-17 | 2018-06-14 | Neural Diabetes Llc | SYSTEM AND APPARATUS FOR MONITORING PANCREATIC BETACLE FUNCTION TO ENHANCE GLUCOSE HOMEOSTASE AND INSULIN PRODUCTION |
| US9044245B2 (en) | 2011-01-05 | 2015-06-02 | Medtronic Ablation Frontiers Llc | Multipolarity epicardial radiofrequency ablation |
| AU2012207357B2 (en) | 2011-01-19 | 2016-07-28 | Fractyl Health, Inc. | Devices and methods for the treatment of tissue |
| US20120191083A1 (en) | 2011-01-20 | 2012-07-26 | Hansen Medical, Inc. | System and method for endoluminal and translumenal therapy |
| EP2667812A1 (en) | 2011-01-28 | 2013-12-04 | Medtronic Ardian Luxembourg S.à.r.l. | Ablation catheter equipped with a shape memory material |
| US20140012251A1 (en) | 2011-03-07 | 2014-01-09 | Tidal Wave Technology, Inc. | Ablation devices and methods |
| EP2688502A1 (en) | 2011-03-25 | 2014-01-29 | Medtronic Ablation Frontiers LLC | Cooling systems for electrode arrays |
| US8738127B1 (en) | 2011-04-20 | 2014-05-27 | Metacure Limited | Method of treating a patient |
| US9061153B1 (en) | 2011-04-20 | 2015-06-23 | Metacure Limited | Method of treating a patient |
| WO2012148966A2 (en) | 2011-04-25 | 2012-11-01 | Brian Kelly | Apparatus and methods related to selective thermal insulation of cryogenic balloons for limited cryogenic ablation of vessel walls |
| WO2012149205A1 (en) * | 2011-04-27 | 2012-11-01 | Dolan Mark J | Nerve impingement systems including an intravascular prosthesis and an extravascular prosthesis and associated systems and methods |
| US8909316B2 (en) | 2011-05-18 | 2014-12-09 | St. Jude Medical, Cardiology Division, Inc. | Apparatus and method of assessing transvascular denervation |
| US9220433B2 (en) | 2011-06-30 | 2015-12-29 | Biosense Webster (Israel), Ltd. | Catheter with variable arcuate distal section |
| WO2013009977A1 (en) | 2011-07-12 | 2013-01-17 | David Lambert | Device for reducing renal sympathetic nerve activity |
| WO2013012892A2 (en) | 2011-07-19 | 2013-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | Treatments for diabetes mellitus and obesity |
| US20130035681A1 (en) | 2011-08-04 | 2013-02-07 | Boston Scientific Scimed, Inc. | Novel catheter for contiguous rf ablation |
| DE112012003250T5 (de) | 2011-08-05 | 2014-04-30 | Mc10, Inc. | Katheder Ballon-Verfahren und Vorrichtung unter Einsatz von Abtastelementen |
| US9278196B2 (en) | 2011-08-24 | 2016-03-08 | Ablative Solutions, Inc. | Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation |
| US20130053792A1 (en) | 2011-08-24 | 2013-02-28 | Ablative Solutions, Inc. | Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation |
| US9056185B2 (en) | 2011-08-24 | 2015-06-16 | Ablative Solutions, Inc. | Expandable catheter system for fluid injection into and deep to the wall of a blood vessel |
| EP2789301B1 (en) | 2011-08-25 | 2017-02-22 | Covidien LP | Systems and devices for treatment of luminal tissue |
| AU2012303701B2 (en) | 2011-08-26 | 2014-02-27 | Symap Medical (Suzhou), Ltd | System and method for locating and identifying functional nerves innervating wall of arteries and catheters for same |
| US8702619B2 (en) | 2011-08-26 | 2014-04-22 | Symap Holding Limited | Mapping sympathetic nerve distribution for renal ablation and catheters for same |
| US20130066308A1 (en) | 2011-08-31 | 2013-03-14 | Jaime Landman | Ablation-based therapy for bladder pathologies |
| US20140214018A1 (en) | 2011-09-01 | 2014-07-31 | Perseus-Biomed Inc. | Method and system for tissue modulation |
| US9084611B2 (en) | 2011-09-22 | 2015-07-21 | The George Washington University | Systems and methods for visualizing ablated tissue |
| US9750565B2 (en) | 2011-09-30 | 2017-09-05 | Medtronic Advanced Energy Llc | Electrosurgical balloons |
| ES2757682T3 (es) * | 2011-09-30 | 2020-04-29 | Covidien Lp | Dispositivo de entrega de energía y procedimientos de uso |
| US20130090578A1 (en) | 2011-10-10 | 2013-04-11 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation |
| EP2765942B1 (en) | 2011-10-10 | 2016-02-24 | Boston Scientific Scimed, Inc. | Medical devices including ablation electrodes |
| US9420955B2 (en) | 2011-10-11 | 2016-08-23 | Boston Scientific Scimed, Inc. | Intravascular temperature monitoring system and method |
| US20130090649A1 (en) | 2011-10-11 | 2013-04-11 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation |
| EP2765941A1 (en) | 2011-10-11 | 2014-08-20 | Boston Scientific Scimed, Inc. | Ablation catheter with insulated tip |
| WO2013055815A1 (en) | 2011-10-11 | 2013-04-18 | Boston Scientific Scimed, Inc. | Off -wall electrode device for nerve modulation |
| US20130090650A1 (en) | 2011-10-11 | 2013-04-11 | Boston Scientific Scimed, Inc. | Renal nerve ablation cooling device and technique |
| US9364284B2 (en) | 2011-10-12 | 2016-06-14 | Boston Scientific Scimed, Inc. | Method of making an off-wall spacer cage |
| US20130096550A1 (en) | 2011-10-18 | 2013-04-18 | Boston Scientific Scimed, Inc. | Ablative catheter with electrode cooling and related methods of use |
| WO2013058962A1 (en) | 2011-10-18 | 2013-04-25 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
| US20130110106A1 (en) | 2011-10-28 | 2013-05-02 | Boston Scientific Scimed, Inc. | Expandable structure for off-wall ablation electrode |
| DE202011107537U1 (de) | 2011-11-05 | 2011-12-13 | Peter Osypka | Ballon Katheter |
| EP3287067B1 (en) * | 2011-11-07 | 2019-10-30 | Medtronic Ardian Luxembourg S.à.r.l. | Endovascular nerve monitoring devices and associated systems |
| WO2013070724A1 (en) | 2011-11-08 | 2013-05-16 | Boston Scientific Scimed, Inc. | Ostial renal nerve ablation |
| WO2013074683A1 (en) | 2011-11-14 | 2013-05-23 | Boston Scientific Scimed, Inc. | Ablation catheter with cryothermal balloon |
| EP2779929A1 (en) | 2011-11-15 | 2014-09-24 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation monitoring |
| US20140350553A1 (en) | 2011-11-21 | 2014-11-27 | Denerve Inc. | Renal artery ablation catheter and system |
| CN107080561B (zh) | 2011-12-09 | 2020-09-11 | 麦特文申公司 | 用于神经调节的设备、系统和方法 |
| WO2013096920A1 (en) | 2011-12-23 | 2013-06-27 | Vessix Vascular, Inc. | Methods and apparatuses for remodeling tissue of or adjacent to a body passage |
| EP2797533A1 (en) | 2011-12-28 | 2014-11-05 | Boston Scientific Scimed, Inc. | Balloon expandable multi-electrode rf ablation catheter |
| US9039700B2 (en) | 2011-12-29 | 2015-05-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Irrigated ablation catheter with contact force sensing mechanism |
| EP2797539B1 (en) | 2011-12-29 | 2020-12-02 | St. Jude Medical Atrial Fibrillation Division Inc. | System for optimized coupling of ablation catheters to body tissues and evaluation of lesions formed by the catheters |
| EP2797535B1 (en) | 2011-12-29 | 2020-10-21 | Boston Scientific Scimed, Inc. | Device for renal nerve modulation monitoring |
| US8945025B2 (en) | 2011-12-30 | 2015-02-03 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Catheter with atraumatic tip |
| US9687289B2 (en) | 2012-01-04 | 2017-06-27 | Biosense Webster (Israel) Ltd. | Contact assessment based on phase measurement |
| WO2013111136A2 (en) | 2012-01-25 | 2013-08-01 | CardioSonic Ltd. | Selective reduction of nerve activity |
| US9220556B2 (en) | 2012-01-27 | 2015-12-29 | Medtronic Cryocath Lp | Balloon design to enhance cooling uniformity |
| CN104203348A (zh) | 2012-01-30 | 2014-12-10 | 维特罗纳斯有限公司 | 组织坏死方法和装置 |
| WO2013126489A1 (en) | 2012-02-24 | 2013-08-29 | Isolase, Ltd. | Improvements in ablation techniques for the treatment of atrial fibrillation |
| KR102245697B1 (ko) | 2012-02-27 | 2021-04-28 | 프랙틸 래브러토리스 인코포레이티드 | 조직의 치료를 위한 열 절제 시스템，장치 및 방법 |
| US9089341B2 (en) | 2012-02-28 | 2015-07-28 | Surefire Medical, Inc. | Renal nerve neuromodulation device |
| US20130231658A1 (en) | 2012-03-01 | 2013-09-05 | Boston Scientific Scimed, Inc. | Expandable ablation device and methods for nerve modulation |
| EP2819604A1 (en) | 2012-03-01 | 2015-01-07 | Boston Scientific Scimed, Inc. | Off-wall and contact electrode devices and methods for nerve modulation |
| AU2013230479A1 (en) | 2012-03-04 | 2014-09-11 | Medtronic Ardian Luxembourg Sarl | Generator assemblies for neuromodulation therapy and associated systems and methods |
| CN104254367A (zh) | 2012-03-07 | 2014-12-31 | 美敦力阿迪安卢森堡有限公司 | 肾神经的选择性调制 |
| US10737123B2 (en) | 2012-03-08 | 2020-08-11 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation and associated systems and methods for the management of pain |
| AU2013230774B2 (en) | 2012-03-08 | 2015-12-03 | Medtronic Af Luxembourg S.A.R.L. | Gastrointestinal neuromodulation and associated systems and methods |
| RU2644933C2 (ru) | 2012-03-08 | 2018-02-14 | Медтроник Аф Люксембург Сарл | Отбор образцов биомаркеров в контексте устройств для нейромодуляции и соответствующие системы и способы |
| US20150111918A1 (en) | 2012-03-08 | 2015-04-23 | Medtronic Ardian Luxembourg S.a.r.l | Immune system neuromodulation and associated systems and methods |
| WO2013134780A1 (en) | 2012-03-09 | 2013-09-12 | Petersohn M D Jeffrey | Device for therapeutic delivery of radio frequency energy |
| BR112014024695B1 (pt) | 2012-04-02 | 2021-12-28 | Medical Development Technologies S.A. | Implante para tratamento de hipertensão arterial pelo bloqueio dos sinais nervosos simpáticos renais através de ablação por meio de aquecimento e sistema para tratamento de hipertensão arterial pelo bloqueio dos sinais nervosos simpáticos renais através de ablação por meio de aquecimento |
| EP2838598B1 (en) | 2012-04-19 | 2020-01-15 | Fractyl Laboratories, Inc. | Tissue expansion devices |
| US20130296840A1 (en) | 2012-05-01 | 2013-11-07 | Medtronic Ablation Frontiers Llc | Systems and methods for detecting tissue contact during ablation |
| US9848950B2 (en) | 2012-04-27 | 2017-12-26 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and devices for localized disease treatment by ablation |
| US20130289678A1 (en) * | 2012-04-27 | 2013-10-31 | Medtronic Ardian Luxembourg S.a r.1. | Therapy systems including hyperthermic energy delivery elements and cryogenic applicators and associated methods |
| WO2013165920A1 (en) | 2012-04-29 | 2013-11-07 | Synecor Llc | Intravascular electrode arrays for neuromodulation |
| WO2013165584A1 (en) | 2012-05-04 | 2013-11-07 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System and method for controlling delivery of ablation energy to tissue |
| US20140207136A1 (en) | 2012-05-04 | 2014-07-24 | St. Jude Medical, Inc. | Multiple staggered electrodes connected via flexible joints |
| WO2013169927A1 (en) | 2012-05-08 | 2013-11-14 | Boston Scientific Scimed, Inc. | Renal nerve modulation devices |
| CA2872189A1 (en) | 2012-05-11 | 2013-11-14 | William W. CHANG | Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods |
| EP2854680A4 (en) | 2012-06-01 | 2016-07-20 | Cibiem Inc | METHODS AND DEVICES FOR ABLATION OF CRYOGENIC CAROTID BODY |
| US8951296B2 (en) | 2012-06-29 | 2015-02-10 | Medtronic Ardian Luxembourg S.A.R.L. | Devices and methods for photodynamically modulating neural function in a human |
| EP2869751A4 (en) * | 2012-07-04 | 2016-04-13 | Cibiem Inc | DEVICES AND SYSTEMS FOR HEADACHE BODY ABATEMENT |
| JP2015521894A (ja) | 2012-07-05 | 2015-08-03 | エムシー１０ インコーポレイテッドＭｃ１０，Ｉｎｃ． | 流量センシングを含むカテーテルデバイス |
| US9295842B2 (en) | 2012-07-05 | 2016-03-29 | Mc10, Inc. | Catheter or guidewire device including flow sensing and use thereof |
| US20140025069A1 (en) | 2012-07-17 | 2014-01-23 | Boston Scientific Scimed, Inc. | Renal nerve modulation catheter design |
| US20150176740A1 (en) | 2012-07-24 | 2015-06-25 | Woco Industrietechnik Gmbh | Connecting device and connecting system with same |
| EP2879605A4 (en) | 2012-07-30 | 2016-04-06 | Fractyl Lab Inc | ELECTRICITY CONTROL SYSTEMS, DEVICES AND METHOD FOR TREATMENT OF TISSUE |
| WO2014022644A1 (en) | 2012-08-03 | 2014-02-06 | Muffin Incorporated | Weeping balloon catheter with ultrasound element |
| AU2013300176B2 (en) | 2012-08-06 | 2017-08-17 | Shockwave Medical, Inc. | Low profile electrodes for an angioplasty shock wave catheter |
| WO2014026055A1 (en) | 2012-08-09 | 2014-02-13 | Fractyl Laboratories Inc. | Ablation systems, devices and methods for the treatment of tissue |
| US20140067029A1 (en) | 2012-08-28 | 2014-03-06 | Boston Scientific Scimed, Inc. | Renal nerve modulation and ablation catheter electrode design |
| US8612022B1 (en) | 2012-09-13 | 2013-12-17 | Invatec S.P.A. | Neuromodulation catheters and associated systems and methods |
| WO2014047355A1 (en) | 2012-09-19 | 2014-03-27 | Denervx LLC | Cooled microwave denervation |
| CN104812325A (zh) | 2012-09-26 | 2015-07-29 | 波士顿科学国际有限公司 | 用于肾神经消融支持多个电极的具有肋脊结构的导管 |
| US20140088575A1 (en) | 2012-09-27 | 2014-03-27 | Trimedyne, Inc. | Devices for effective and uniform denervation of nerves and unique methods of use thereof |
| US9522033B2 (en) | 2012-10-02 | 2016-12-20 | Covidien Lp | Devices and methods for optical detection of tissue contact |
| US9668802B2 (en) | 2012-10-02 | 2017-06-06 | Covidien Lp | Devices and methods for optical detection of tissue contact |
| WO2014055997A1 (en) | 2012-10-05 | 2014-04-10 | Fractyl Laboratories Inc. | Methods, systems and devices for performing multiple treatments on a patient |
| WO2014060206A1 (de) | 2012-10-17 | 2014-04-24 | Albert Daxer | Vorrichtung und verfahren zur bestrahlung des auges |
| US20140110296A1 (en) | 2012-10-19 | 2014-04-24 | Medtronic Ardian Luxembourg S.A.R.L. | Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods |
| JP6204483B2 (ja) | 2012-11-02 | 2017-09-27 | べシックス・バスキュラー・インコーポレイテッド | バルーンアセンブリ |
| US20150272666A1 (en) | 2012-11-02 | 2015-10-01 | Lixiao Wang | Chemical Ablation Formulations and Methods of Treatments for Various Diseases |
| US12208224B2 (en) | 2012-11-02 | 2025-01-28 | Neurotronic, Inc. | Chemical ablation and method of treatment for various diseases |
| US20200086093A1 (en) | 2012-11-02 | 2020-03-19 | Neurotronic, Inc. | Chemical ablation and method of treatment for various diseases |
| US10537375B2 (en) | 2015-04-24 | 2020-01-21 | Neurotronic, Inc. | Chemical ablation and method of treatment for various diseases |
| US9272132B2 (en) | 2012-11-02 | 2016-03-01 | Boston Scientific Scimed, Inc. | Medical device for treating airways and related methods of use |
| US9283374B2 (en) | 2012-11-05 | 2016-03-15 | Boston Scientific Scimed, Inc. | Devices and methods for delivering energy to body lumens |
| US9066725B2 (en) | 2012-12-06 | 2015-06-30 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Irrigant distribution system for electrodes |
| US20140163652A1 (en) | 2012-12-10 | 2014-06-12 | Thomas Witzel | Method for treating and repairing mitral valve annulus |
| WO2014091401A2 (en) | 2012-12-10 | 2014-06-19 | Perseus-Biomed Inc. | Dynamic denervation procedures and systems for the implementation thereof |
| US20140171936A1 (en) | 2012-12-17 | 2014-06-19 | Biosense Webster (Israel) Ltd. | Irrigated catheter tip with temperature sensor and optic fiber arrays |
| US20140188103A1 (en) | 2012-12-31 | 2014-07-03 | Volcano Corporation | Methods and Apparatus for Neuromodulation Utilizing Optical-Acoustic Sensors |
| US20150335919A1 (en) | 2012-12-31 | 2015-11-26 | Perseus-Biomed Inc. | Phased array energy aiming and tracking for ablation treatment |
| WO2014110579A1 (en) | 2013-01-14 | 2014-07-17 | Boston Scientific Scimed, Inc. | Renal nerve ablation catheter |
| EP3777703B1 (en) | 2013-02-08 | 2023-04-05 | Acutus Medical Inc. | Expandable catheter assembly with flexible printed circuit board |
| US9179971B2 (en) | 2013-02-11 | 2015-11-10 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Printed electrode catheter |
| US20140243807A1 (en) | 2013-02-22 | 2014-08-28 | James Margolis | Devices and methods for denervation of the nerves surrounding the pulmonary veins for treatment of atrial fibrillation |
| WO2014130954A1 (en) | 2013-02-22 | 2014-08-28 | Cibiem, Inc. | Endovascular catheters for trans-superficial temporal artery transmural carotid body modulation |
| US20140249524A1 (en) | 2013-03-01 | 2014-09-04 | Boston Scientific Scimed, Inc. | System and method for performing renal nerve modulation |
| US20140303617A1 (en) | 2013-03-05 | 2014-10-09 | Neuro Ablation, Inc. | Intravascular nerve ablation devices & methods |
| EP2964127A4 (en) | 2013-03-08 | 2016-12-07 | Symple Surgical Inc | BALLOON CATHETER CONTROL PANEL WITH MICROWAVE MIXER |
| US10076384B2 (en) | 2013-03-08 | 2018-09-18 | Symple Surgical, Inc. | Balloon catheter apparatus with microwave emitter |
| US11147990B2 (en) | 2013-03-12 | 2021-10-19 | Acoustic Medsystems, Inc. | Ultrasound therapy catheter with multi-chambered balloons for transluminal longitudinal positioning |
| WO2014163990A1 (en) | 2013-03-12 | 2014-10-09 | Boston Scientific Scimed, Inc. | Medical systems and methods for modulating nerves |
| CN105188587A (zh) | 2013-03-13 | 2015-12-23 | 波士顿科学医学有限公司 | 具有线性离子化传导性气球的可转向消融设备 |
| WO2014165062A1 (en) | 2013-03-13 | 2014-10-09 | Kardium, Inc. | Detecting improper energy transmission configuration in medical device system |
| US9808311B2 (en) | 2013-03-13 | 2017-11-07 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
| CN106178294B (zh) | 2013-03-14 | 2018-11-20 | 瑞蔻医药有限公司 | 一种血管内的基于超声波的消融系统 |
| US10499980B2 (en) | 2013-03-14 | 2019-12-10 | Spiration, Inc. | Flexible RF ablation needle |
| US9131982B2 (en) | 2013-03-14 | 2015-09-15 | St. Jude Medical, Cardiology Division, Inc. | Mediguide-enabled renal denervation system for ensuring wall contact and mapping lesion locations |
| US20140316254A1 (en) | 2013-03-15 | 2014-10-23 | Clph, Llc | Apparatus and methods for optical position sensing |
| US9345540B2 (en) | 2013-03-15 | 2016-05-24 | Medtronic Ablation Frontiers Llc | Contact specific RF therapy balloon |
| US20140276707A1 (en) | 2013-03-15 | 2014-09-18 | Boston Scientific Neuromodulation Corporation | System and method of using evoked compound action potentials to minimize vessel trauma during nerve ablation |
| US9848948B2 (en) | 2013-03-15 | 2017-12-26 | Biosense Webster (Israel) Ltd. | Catheter adapted for use with guide wire for accessing vessels |
| US9179974B2 (en) | 2013-03-15 | 2015-11-10 | Medtronic Ardian Luxembourg S.A.R.L. | Helical push wire electrode |
| US10265122B2 (en) | 2013-03-15 | 2019-04-23 | Boston Scientific Scimed, Inc. | Nerve ablation devices and related methods of use |
| US9066726B2 (en) | 2013-03-15 | 2015-06-30 | Medtronic Ardian Luxembourg S.A.R.L. | Multi-electrode apposition judgment using pressure elements |
| US9333113B2 (en) | 2013-03-15 | 2016-05-10 | Abbott Cardiovascular Systems Inc. | System and method for denervation |
| US9055950B2 (en) | 2013-03-15 | 2015-06-16 | Chemo S.A. France | Method and system for delivering a tissue treatment using a balloon-catheter system |
| HK1219401A1 (zh) | 2013-04-08 | 2017-04-07 | Apama Medical, Inc. | 心臟消融導管及其使用方法 |
| US10098694B2 (en) | 2013-04-08 | 2018-10-16 | Apama Medical, Inc. | Tissue ablation and monitoring thereof |
| US10548663B2 (en) | 2013-05-18 | 2020-02-04 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation catheters with shafts for enhanced flexibility and control and associated devices, systems, and methods |
| EP2999423B1 (en) | 2013-05-20 | 2021-03-31 | Mayo Foundation For Medical Education And Research | Devices for ablation of tissue |
| US20140350551A1 (en) | 2013-05-21 | 2014-11-27 | St. Jude Medical, Cardiology Division, Inc. | Electrode assembly for catheter system |
| EP3003191A4 (en) | 2013-06-05 | 2017-02-08 | Metavention, Inc. | Modulation of targeted nerve fibers |
| CN105338885B (zh) | 2013-06-11 | 2018-02-02 | 圣犹达医疗用品电生理部门有限公司 | 多电极阻抗感测 |
| JP2016523147A (ja) | 2013-06-21 | 2016-08-08 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 同乗型電極支持体を備えた腎除神経バルーンカテーテル |
| JP6499163B2 (ja) | 2013-06-21 | 2019-04-10 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 医療器具 |
| EP3010436A1 (en) | 2013-06-21 | 2016-04-27 | Boston Scientific Scimed, Inc. | Medical devices for renal nerve ablation having rotatable shafts |
| US9707036B2 (en) | 2013-06-25 | 2017-07-18 | Boston Scientific Scimed, Inc. | Devices and methods for nerve modulation using localized indifferent electrodes |
| CN105358084B (zh) | 2013-07-01 | 2018-11-09 | 波士顿科学国际有限公司 | 用于肾神经消融的医疗器械 |
| US9333033B2 (en) | 2013-07-11 | 2016-05-10 | Biosense Webster (Israel) Ltd. | Detection of ablation electrode contact with tissue |
| CN105377170A (zh) | 2013-07-11 | 2016-03-02 | 波士顿科学国际有限公司 | 具有可伸展电极组件的医疗装置 |
| CN105377169B (zh) | 2013-07-11 | 2019-04-19 | 波士顿科学国际有限公司 | 用于神经调制的装置和方法 |
| US20150018820A1 (en) | 2013-07-12 | 2015-01-15 | Boston Scientific Scimed, Inc. | Apparatus and methods for renal denervation |
| CN104298516B (zh) | 2013-07-18 | 2017-12-08 | 京瓷办公信息系统株式会社 | 电子设备以及挂起控制方法 |
| EP3049007B1 (en) | 2013-07-19 | 2019-06-12 | Boston Scientific Scimed, Inc. | Spiral bipolar electrode renal denervation balloon |
| WO2015013301A1 (en) | 2013-07-22 | 2015-01-29 | Boston Scientific Scimed, Inc. | Renal nerve ablation catheter having twist balloon |
| US20150045787A1 (en) | 2013-08-09 | 2015-02-12 | Medtronic-Xomed, Inc. | Electrosurgical device and method |
| EP3033021A2 (en) | 2013-08-14 | 2016-06-22 | La Vita Technologies Ltd. | Methods and apparatuses for treating auto-immune diseases by ablative neuromodulation |
| US20150051595A1 (en) | 2013-08-19 | 2015-02-19 | James Margolis | Devices and methods for denervation of the nerves surrounding the pulmonary veins for treatment of atrial fibrillation |
| WO2015027096A1 (en) | 2013-08-22 | 2015-02-26 | Boston Scientific Scimed, Inc. | Flexible circuit having improved adhesion to a renal nerve modulation balloon |
| US9913684B2 (en) | 2013-08-23 | 2018-03-13 | Oscor Inc. | Steerable ablation catheter for renal denervation |
| US9326816B2 (en) | 2013-08-30 | 2016-05-03 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation systems having nerve monitoring assemblies and associated devices, systems, and methods |
| US9895194B2 (en) | 2013-09-04 | 2018-02-20 | Boston Scientific Scimed, Inc. | Radio frequency (RF) balloon catheter having flushing and cooling capability |
| WO2015038947A1 (en) | 2013-09-13 | 2015-03-19 | Boston Scientific Scimed, Inc. | Ablation balloon with vapor deposited cover layer |
| US9204929B2 (en) | 2013-09-16 | 2015-12-08 | Biosense Webster (Israel) Ltd. | Basket catheter with deflectable spine |
| WO2015040557A1 (en) | 2013-09-17 | 2015-03-26 | Krishnan Subramaniam C | Dual catheter ablation system |
| CA2923007C (en) | 2013-09-25 | 2018-09-18 | Halliburton Energy Services, Inc. | Workflow adjustment methods and systems for logging operations |
| US10687889B2 (en) | 2013-10-11 | 2020-06-23 | Biosense Webster (Israel) Ltd. | Patient-specific pre-shaped cardiac catheter |
| US11246654B2 (en) | 2013-10-14 | 2022-02-15 | Boston Scientific Scimed, Inc. | Flexible renal nerve ablation devices and related methods of use and manufacture |
| US20150105772A1 (en) | 2013-10-14 | 2015-04-16 | Boston Scientific Scimed, Inc. | Devices and methods for nerve modulation |
| CN105592778B (zh) | 2013-10-14 | 2019-07-23 | 波士顿科学医学有限公司 | 高分辨率心脏标测电极阵列导管 |
| WO2015057584A1 (en) | 2013-10-15 | 2015-04-23 | Boston Scientific Scimed, Inc. | Medical device balloon |
| JP6259099B2 (ja) | 2013-10-18 | 2018-01-10 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 可撓性を備える導電性ワイヤを備えるバルーン・カテーテル、並びに関連する使用および製造方法 |
| US20150119878A1 (en) | 2013-10-24 | 2015-04-30 | St. Jude Medical, Cardiology Division, Inc. | Electrode assembly having asymmetric electrode placement |
| US20150119877A1 (en) | 2013-10-25 | 2015-04-30 | Covidien Lp | Electrode ablation balloon catheter |
| JP2016534842A (ja) | 2013-10-25 | 2016-11-10 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 除神経フレックス回路における埋め込み熱電対 |
| US20150119875A1 (en) | 2013-10-25 | 2015-04-30 | Ablative Solutions, Inc. | Method and apparatus for sparing pain conducting nerves during renal denervation |
| US10390881B2 (en) | 2013-10-25 | 2019-08-27 | Denervx LLC | Cooled microwave denervation catheter with insertion feature |
| EP3062722B1 (en) | 2013-10-28 | 2019-03-20 | St. Jude Medical, Cardiology Division, Inc. | Electrode assembly for catheter system including interlinked struts |
| US9861433B2 (en) | 2013-11-05 | 2018-01-09 | St. Jude Medical, Cardiology Division, Inc. | Helical-shaped ablation catheter and methods of use |
| WO2015069446A1 (en) | 2013-11-06 | 2015-05-14 | Towe Bruce C | Ultrasound induced modulation of blood glucose levels |
| CN105682597B (zh) | 2013-11-07 | 2018-06-12 | 圣犹达医疗用品心脏病学部门有限公司 | 具有接触力感测尖端的医疗装置 |
| CN105873536A (zh) | 2013-11-20 | 2016-08-17 | 波士顿科学医学有限公司 | 消融医疗装置以及用于制备和使用消融医疗装置的方法 |
| US10568686B2 (en) | 2013-11-21 | 2020-02-25 | Biosense Webster (Israel) Ltd. | Multi-electrode balloon catheter with circumferential and point electrodes |
| US10105073B2 (en) | 2013-11-21 | 2018-10-23 | Biosense Webster (Israel) Ltd | Flexible multiple-arm diagnostic catheter |
| CN106132468B (zh) | 2013-11-29 | 2020-03-13 | 导管治疗有限公司 | 网篮状导管和制造方法 |
| US9993279B2 (en) | 2013-12-06 | 2018-06-12 | Medtronic Cryocath Lp | Distal balloon impedance and temperature recording to monitor pulmonary vein ablation and occlusion |
| WO2015103617A1 (en) | 2014-01-06 | 2015-07-09 | Boston Scientific Scimed, Inc. | Tear resistant flex circuit assembly |
| EP3091923A1 (en) | 2014-01-06 | 2016-11-16 | Boston Scientific Scimed, Inc. | Sympathetic nerve ablation devices with an expansion-limiting member |
| JP2017501843A (ja) | 2014-01-10 | 2017-01-19 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | フレキシブル回路アセンブリを有する医療装置 |
| US20150209107A1 (en) | 2014-01-24 | 2015-07-30 | Denervx LLC | Cooled microwave denervation catheter configuration |
| CN106572881B (zh) | 2014-02-04 | 2019-07-26 | 波士顿科学国际有限公司 | 热传感器在双极电极上的替代放置 |
| JP2017505215A (ja) | 2014-02-07 | 2017-02-16 | ベルブ メディカル， インコーポレイテッド | 腎盂の切除のための方法およびシステム |
| US20150230859A1 (en) | 2014-02-19 | 2015-08-20 | Kevin Mauch | Bi-directional deployment of neuromodulation devices and associated systems and methods |
| US9579149B2 (en) | 2014-03-13 | 2017-02-28 | Medtronic Ardian Luxembourg S.A.R.L. | Low profile catheter assemblies and associated systems and methods |
| US10543039B2 (en) | 2014-03-18 | 2020-01-28 | Boston Scientific Scimed, Inc. | Nerve ablation devices and related methods of use and manufacture |
| US9974597B2 (en) | 2014-03-19 | 2018-05-22 | Boston Scientific Scimed, Inc. | Systems and methods for assessing and treating tissue |
| US10194979B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
| JP6076937B2 (ja) | 2014-03-28 | 2017-02-08 | 株式会社日立製作所 | パケット伝送システムおよびネットワークコントローラ |
| WO2015159296A1 (en) | 2014-04-17 | 2015-10-22 | Digma Medical Ltd. | Methods and systems for blocking neural activity in an organ of a subject, preferably in the small intestine or the duodenum |
| WO2015161211A1 (en) | 2014-04-17 | 2015-10-22 | Boston Scientific Scimed, Inc. | Devices and methods for therapeutic heat treatment |
| CN106659531A (zh) | 2014-05-07 | 2017-05-10 | 毕达哥拉斯医疗有限公司 | 受控组织消融技术 |
| WO2015183952A1 (en) | 2014-05-28 | 2015-12-03 | Boston Scientific Scimed, Inc. | Nerve modulation devices with cooling capabilities |
| EP2952162A1 (en) | 2014-06-02 | 2015-12-09 | Gelanus B.V. | Assembly, esophagus catheter and method for controlling a temperature of at least a part of a person, in particular the brain of the person |
| US9585588B2 (en) | 2014-06-03 | 2017-03-07 | Boston Scientific Scimed, Inc. | Electrode assembly having an atraumatic distal tip |
| EP3151773B1 (en) | 2014-06-04 | 2018-04-04 | Boston Scientific Scimed, Inc. | Electrode assembly |
| US20150359589A1 (en) | 2014-06-11 | 2015-12-17 | Medtronic Ardian Luxembourg S.A.R.L. | Intravascular neuromodulation device having a helical therapeutic assembly with proud portions and associated methods |
| JP6313470B2 (ja) | 2014-06-20 | 2018-04-18 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 印刷された構成要素を備えた交感神経アブレーションのための医療機器およびその製造方法 |
| WO2016018754A1 (en) | 2014-07-28 | 2016-02-04 | Boston Scientific Scimed, Inc. | Multiple lead electrode probe for controlled tissue ablation |
| US20160058502A1 (en) | 2014-08-27 | 2016-03-03 | Boston Scientific Scimed, Inc. | Devices for damaging nerves and related methods of use |
| US20160058503A1 (en) | 2014-08-28 | 2016-03-03 | Medtronic Ardian Luxembourg S.a.r.I. | Methods for modulating renal nerve tissue and associated systems and devices |
| JP6282209B2 (ja) | 2014-10-08 | 2018-02-21 | 日本ライフライン株式会社 | ケミカルアブレーション装置およびケミカルアブレーションシステム |
| US9314208B1 (en) | 2014-10-28 | 2016-04-19 | Biosense Webster (Israel) Ltd. | Basket catheter with microelectrode array distal tip |
| US10286191B2 (en) | 2014-10-30 | 2019-05-14 | Neurotronic, Inc. | Chemical ablation and method of treatment for various diseases |
| WO2016081650A1 (en) | 2014-11-19 | 2016-05-26 | Advanced Cardiac Therapeutics, Inc. | Ablation devices, systems and methods of using a high-resolution electrode assembly |
| WO2016090175A1 (en) | 2014-12-03 | 2016-06-09 | Metavention, Inc. | Systems and methods for modulating nerves or other tissue |
| US9795780B2 (en) | 2014-12-18 | 2017-10-24 | Abbott Cardiovascular Systems Inc. | System for denervation |
| US20160175041A1 (en) | 2014-12-22 | 2016-06-23 | Biosense Webster (Israel) Ltd. | Balloon for ablation around pulmonary veins |
| US10368934B2 (en) | 2015-01-14 | 2019-08-06 | Covidien Lp | Arrangement of multi-channel bipolar electrode zones to minimize leakage and edge effects |
| US9974946B2 (en) | 2015-04-07 | 2018-05-22 | NeuroTronik IP Holding (Jersey) Limited | Inflatable intravascular electrode supports for neuromodulation |
| EP3360497B1 (en) | 2015-02-03 | 2024-05-22 | Shanghai Golden Leaf Med Tec Co., Ltd. | Radio-frequency ablation catheter having spiral structure and device thereof |
| WO2016138508A1 (en) | 2015-02-27 | 2016-09-01 | Lee Randall J | Pericardial access catheters and methods for use |
| US9872985B2 (en) | 2015-03-03 | 2018-01-23 | Georgia Tech Research Corporation | Glucose regulation via electrical stimulation of nerves innervating the liver |
| JP6265434B2 (ja) | 2015-03-27 | 2018-01-24 | 日本ライフライン株式会社 | バルーン型アブレーションカテーテルおよびアブレーションカテーテル装置 |
| US9855317B2 (en) | 2015-04-27 | 2018-01-02 | Reflex Medical, Inc. | Systems and methods for sympathetic cardiopulmonary neuromodulation |
| EP3294135A4 (en) | 2015-05-12 | 2019-01-09 | Mir Imran | DEVICE, SYSTEM AND METHOD FOR MEASURING PRESSURE IN THE HARNTRAKT |
| CN115040232A (zh) | 2015-05-12 | 2022-09-13 | 爱尔兰国立高威大学 | 用于治疗性鼻神经调节的装置及相关的方法和系统 |
| US11675795B2 (en) | 2015-05-15 | 2023-06-13 | Yahoo Assets Llc | Method and system for ranking search content |
| US10307580B2 (en) | 2015-06-25 | 2019-06-04 | Cardiovascular Systems, Inc. | Devices, systems and methods for enhancing intraluminal drug delivery and uptake |
| WO2017007678A1 (en) | 2015-07-07 | 2017-01-12 | Boston Scientific Scimed, Inc. | Methods and devices for maintaining an open pathway in a vessel |
| US20170014639A1 (en) | 2015-07-13 | 2017-01-19 | Symple Surgical, Inc. | Cable with microwave emitter |
| US10827939B2 (en) | 2015-08-03 | 2020-11-10 | Boston Scientific Scimed, Inc. | Steerable tissue mapping and ablation device |
| CN107847197A (zh) | 2015-08-05 | 2018-03-27 | 波士顿科学医学有限公司 | 用于膀胱标测的智能装置 |
| KR101748032B1 (ko) | 2015-09-03 | 2017-06-14 | 한국과학기술원 | 집적회로를 이용한 다중전극 신장신경절제 방법 및 시스템 |
| JP6320978B2 (ja) | 2015-09-28 | 2018-05-09 | 有限会社日本エレクテル | 高周波バルーンカテーテルシステム |
| US10285751B2 (en) | 2015-10-16 | 2019-05-14 | Biosense Webster (Israel) Ltd. | System and method for controlling catheter power based on renal ablation response |
| US20170143405A1 (en) | 2015-11-20 | 2017-05-25 | Covidien Lp | Apparatuses, systems and methods for treating ulcerative colitis and other inflammatory bowel diseases |
| US10813689B2 (en) | 2015-11-25 | 2020-10-27 | Biosense Webster (Israel) Ltd. | Ablation catheter with radial force detection |
| US20170157366A1 (en) | 2015-12-03 | 2017-06-08 | Benny Assif | Urinary catheters, systems and methods for use during treatment of the prostate |
| US10136945B2 (en) | 2015-12-09 | 2018-11-27 | Biosense Webster (Israel) Ltd. | Ablation catheter with light-based contact sensors |
| WO2017146658A1 (en) | 2016-02-24 | 2017-08-31 | Cakmak Yusuf Ozgur | A system for decreasing the blood glucose level |
| WO2017151986A1 (en) | 2016-03-02 | 2017-09-08 | Mir Imran | Urethral catheters and methods for facilitated introduction into the urinary tract |
| EP3216488B1 (en) | 2016-03-10 | 2023-07-12 | BIOTRONIK SE & Co. KG | Delivery system for implantable stimulation devices and corresponding catheters |
| US10653480B2 (en) | 2016-04-28 | 2020-05-19 | Biosense Webster (Israel) Ltd. | Method for constructing irrigated balloon catheter with flexible circuit electrode assembly |
| US10638976B2 (en) | 2016-04-28 | 2020-05-05 | Biosense Webster (Israel) Ltd | Method of constructing irrigated balloon catheter |
| CN109414286B (zh) | 2016-05-02 | 2021-09-07 | 阿弗拉公司 | 导管感应以及冲洗 |
| TW201740884A (zh) | 2016-05-23 | 2017-12-01 | 佳世達科技股份有限公司 | 超音波導管及醫療系統 |
| US10524859B2 (en) | 2016-06-07 | 2020-01-07 | Metavention, Inc. | Therapeutic tissue modulation devices and methods |
| US9743984B1 (en) | 2016-08-11 | 2017-08-29 | Thermedical, Inc. | Devices and methods for delivering fluid to tissue during ablation therapy |
| US20190274687A1 (en) | 2016-09-20 | 2019-09-12 | Neurotronic, Inc. | Magnetic anastomosis devices |
| CN110505900A (zh) | 2017-03-20 | 2019-11-26 | 索尼伟业有限公司 | 用于通过改善患者的射血分数来治疗心力衰竭的方法 |
| DE20160841T1 (de) | 2020-03-04 | 2021-12-09 | Onward Medical B.V. | Ein neuromodulationssystem |
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| US20240325079A1 (en) | 2024-10-03 |
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| US20240325078A1 (en) | 2024-10-03 |
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