US7247302B1
(en)
*
|
1996-08-02 |
2007-07-24 |
Bristol-Myers Squibb Company |
Method for inhibiting immunoglobulin-induced toxicity resulting from the use of immunoglobulins in therapy and in vivo diagnosis
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
EP1443961B1
(en)
*
|
2001-10-25 |
2009-05-06 |
Genentech, Inc. |
Glycoprotein compositions
|
US20090017023A1
(en)
*
|
2002-08-14 |
2009-01-15 |
Macrogenics, Inc. |
FcGammaRIIB Specific Antibodies and Methods of Use Thereof
|
US8946387B2
(en)
*
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8187593B2
(en)
*
|
2002-08-14 |
2012-05-29 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8530627B2
(en)
|
2002-08-14 |
2013-09-10 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8193318B2
(en)
*
|
2002-08-14 |
2012-06-05 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8044180B2
(en)
*
|
2002-08-14 |
2011-10-25 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8968730B2
(en)
|
2002-08-14 |
2015-03-03 |
Macrogenics Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US7960512B2
(en)
*
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
JP2006524039A
(ja)
*
|
2003-01-09 |
2006-10-26 |
マクロジェニクス,インコーポレーテッド |
変異型Fc領域を含む抗体の同定および作製ならびにその利用法
|
KR101297146B1
(ko)
|
2004-05-10 |
2013-08-21 |
마크로제닉스, 인크. |
인간화 FcγRIIB 특이적 항체 및 그의 사용 방법
|
AU2005335714B2
(en)
*
|
2004-11-10 |
2012-07-26 |
Macrogenics, Inc. |
Engineering Fc antibody regions to confer effector function
|
US20070135620A1
(en)
*
|
2004-11-12 |
2007-06-14 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
DK1817340T3
(da)
|
2004-11-12 |
2012-08-13 |
Xencor Inc |
Fc-varianter med ændret binding til fcrn
|
US8367805B2
(en)
*
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
US8802820B2
(en)
*
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
CN101098891B
(zh)
|
2005-01-05 |
2014-05-21 |
F-星生物技术研究与开发有限公司 |
分子中互补决定区以外的区域中工程改造了的具有结合特性的合成免疫球蛋白结构域
|
WO2006104989A2
(en)
*
|
2005-03-29 |
2006-10-05 |
Verenium Corporation |
Altered antibody fc regions and uses thereof
|
WO2006106905A1
(ja)
*
|
2005-03-31 |
2006-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
会合制御によるポリペプチド製造方法
|
CA2605024C
(en)
*
|
2005-04-15 |
2018-05-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
US9284375B2
(en)
*
|
2005-04-15 |
2016-03-15 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
US11254748B2
(en)
|
2005-04-15 |
2022-02-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
US9963510B2
(en)
*
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
DK1919503T3
(en)
|
2005-08-10 |
2014-12-15 |
Macrogenics Inc |
Identification and preparation of antibodies with variant fc regions and methods of use thereof
|
AU2007226752A1
(en)
*
|
2006-03-10 |
2007-09-20 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant heavy chains and methods of using same
|
US9670269B2
(en)
*
|
2006-03-31 |
2017-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of modifying antibodies for purification of bispecific antibodies
|
ES2568436T3
(es)
|
2006-03-31 |
2016-04-29 |
Chugai Seiyaku Kabushiki Kaisha |
Procedimiento para controlar la farmacocinética en sangre de anticuerpos
|
JP5242382B2
(ja)
*
|
2006-04-14 |
2013-07-24 |
株式会社医学生物学研究所 |
エフェクター機能を有するポリペプチド変異体
|
EP2021029B1
(en)
*
|
2006-05-26 |
2014-06-11 |
MacroGenics, Inc. |
Humanized fc gamma riib-specific antibodies and methods of use thereof
|
EP2029173B1
(en)
*
|
2006-06-26 |
2016-07-20 |
MacroGenics, Inc. |
Fc riib-specific antibodies and methods of use thereof
|
WO2008002933A2
(en)
*
|
2006-06-26 |
2008-01-03 |
Macrogenics, Inc. |
Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof
|
AT503889B1
(de)
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
EP2083017A4
(en)
*
|
2006-09-14 |
2011-01-12 |
Med & Biological Lab Co Ltd |
ANTIBODIES HAVING INCREASED ADCC ACTIVITY AND METHOD FOR PRODUCING THE SAME
|
US20080112961A1
(en)
*
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
PL2099823T5
(pl)
|
2006-12-01 |
2023-02-20 |
Seagen Inc. |
Wariant środków wiążących cel i jego zastosowania
|
WO2008140603A2
(en)
*
|
2006-12-08 |
2008-11-20 |
Macrogenics, Inc. |
METHODS FOR THE TREATMENT OF DISEASE USING IMMUNOGLOBULINS HAVING FC REGIONS WITH ALTERED AFFINITIES FOR FCγR ACTIVATING AND FCγR INHIBITING
|
WO2008118324A2
(en)
|
2007-03-26 |
2008-10-02 |
Macrogenics, Inc. |
Composition and method of treating cancer with an anti-uroplakin ib antibody
|
DK2155789T3
(da)
*
|
2007-05-01 |
2013-10-21 |
Res Dev Foundation |
Immunoglobulin-Fc-biblioteker
|
CA2689680C
(en)
|
2007-05-14 |
2017-11-07 |
Novimmune Sa |
Fc receptor-binding polypeptides with modified effector functions
|
WO2009151717A2
(en)
|
2008-04-02 |
2009-12-17 |
Macrogenics, Inc. |
Bcr-complex-specific antibodies and methods of using same
|
US8921279B2
(en)
|
2007-06-26 |
2014-12-30 |
F-Star Biotechnologische Forschungs—und Entwicklungsges. m.b.H |
Display of binding agents
|
AU2016202036B2
(en)
*
|
2007-09-26 |
2017-12-07 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant region
|
SG10201605394SA
(en)
|
2007-09-26 |
2016-08-30 |
Chugai Pharmaceutical Co Ltd |
Modified Antibody Constant Region
|
EP3689912A1
(en)
|
2007-09-26 |
2020-08-05 |
Chugai Seiyaku Kabushiki Kaisha |
Method of modifying isoelectric point of antibody via amino acid substitution in cdr
|
US20100260751A1
(en)
*
|
2007-09-28 |
2010-10-14 |
Raju T Shantha |
Methods and Structural Conformations of Antibody Preparations with Increased Resistance to Proteases
|
RU2531521C2
(ru)
*
|
2007-12-05 |
2014-10-20 |
Чугаи Сейяку Кабусики Кайся |
Антитело против nr10 и его применение
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
ES2532461T3
(es)
|
2007-12-26 |
2015-03-27 |
Xencor, Inc. |
Variantes de FC con enlazamiento alterado a FCRN
|
US8580927B2
(en)
|
2008-01-31 |
2013-11-12 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Engineered antibody constant domain molecules
|
JP5608100B2
(ja)
|
2008-02-08 |
2014-10-15 |
メディミューン,エルエルシー |
低下したFcリガンド親和性を有する抗IFNAR1抗体
|
CA2720368C
(en)
|
2008-04-02 |
2017-08-22 |
Macrogenics, Inc. |
Her2/neu-specific antibodies and methods of using same
|
EP4238993A3
(en)
|
2008-04-11 |
2023-11-29 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
|
EP2113255A1
(en)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Cytotoxic immunoglobulin
|
ES2675730T3
(es)
|
2008-06-04 |
2018-07-12 |
Macrogenics, Inc. |
Anticuerpos con unión alterada a FcRn y métodos de uso de los mismos
|
TWI440469B
(zh)
*
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
CN106432503B
(zh)
|
2008-12-19 |
2020-03-06 |
宏观基因有限公司 |
共价双抗体及其用途
|
EP2378289A4
(en)
*
|
2009-01-15 |
2012-06-20 |
Ulvac Inc |
METHOD FOR MEASURING THE SYSTEMIC CONCENTRATION OF A PROTEINED MEDICINAL PRODUCT
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
JP5787446B2
(ja)
|
2009-03-19 |
2015-09-30 |
中外製薬株式会社 |
抗体定常領域改変体
|
US9228017B2
(en)
|
2009-03-19 |
2016-01-05 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
WO2010110838A2
(en)
*
|
2009-03-25 |
2010-09-30 |
Vet Therapeutics Inc. |
Antibody constant domain regions and uses thereof
|
US20100247484A1
(en)
|
2009-03-31 |
2010-09-30 |
Heinrich Barchet |
Combination therapy of an afucosylated antibody and one or more of the cytokines gm csf, m csf and/or il3
|
JP5501439B2
(ja)
|
2009-04-02 |
2014-05-21 |
ロシュ グリクアート アクチェンゲゼルシャフト |
完全長抗体と単鎖Fabフラグメントとを含む多重特異的抗体
|
MX2011010158A
(es)
|
2009-04-07 |
2011-10-17 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-erbb-2/anti-c-met.
|
EP2417159A1
(en)
|
2009-04-07 |
2012-02-15 |
Roche Glycart AG |
Bispecific anti-erbb-3/anti-c-met antibodies
|
KR101456326B1
(ko)
|
2009-04-07 |
2014-11-12 |
로슈 글리카트 아게 |
3가, 이중특이적 항체
|
RU2595379C2
(ru)
|
2009-04-16 |
2016-08-27 |
АббВай Биотерапеутикс Инк. |
АНТИТЕЛА ПРОТИВ TNF-α И ИХ ПРИМЕНЕНИЯ
|
WO2010131733A1
(ja)
|
2009-05-15 |
2010-11-18 |
中外製薬株式会社 |
抗axl抗体
|
RU2570633C2
(ru)
|
2009-05-27 |
2015-12-10 |
Ф.Хоффманн-Ля Рош Аг |
Три- или тетраспецифические антитела
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
EP2443150B1
(en)
|
2009-06-17 |
2015-01-21 |
AbbVie Biotherapeutics Inc. |
Anti-vegf antibodies and their uses
|
EP2448972A4
(en)
*
|
2009-06-30 |
2012-11-28 |
Res Dev Foundation |
IMMUNOGLOBULIN FC POLYPEPTIDES
|
CA2769595A1
(en)
|
2009-08-14 |
2011-02-17 |
Roche Glycart Ag |
Combination therapy of an afucosylated cd20 antibody with fludarabine and/or mitoxantrone
|
TWI409079B
(zh)
|
2009-08-14 |
2013-09-21 |
Roche Glycart Ag |
非典型岩藻醣化cd20抗體與苯達莫斯汀(bendamustine)之組合療法
|
TW201113037A
(en)
|
2009-08-28 |
2011-04-16 |
Hoffmann La Roche |
Antibodies against CDCP1 for the treatment of cancer
|
TWI412375B
(zh)
|
2009-08-28 |
2013-10-21 |
Roche Glycart Ag |
人類化抗cdcp1抗體
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
CN104945509A
(zh)
|
2009-09-16 |
2015-09-30 |
弗·哈夫曼-拉罗切有限公司 |
包含卷曲螺旋和/或系链的蛋白质复合体及其用途
|
EP2481752B1
(en)
|
2009-09-24 |
2016-11-09 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
CA2773515C
(en)
*
|
2009-09-29 |
2015-04-28 |
Roche Glycart Ag |
Bispecific death receptor agonistic antibodies
|
WO2011044368A1
(en)
|
2009-10-07 |
2011-04-14 |
Macrogenics, Inc. |
Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use
|
CN102753580A
(zh)
|
2009-10-28 |
2012-10-24 |
亚培生物医疗股份有限公司 |
抗egfr抗体及其用途
|
WO2011084496A1
(en)
|
2009-12-16 |
2011-07-14 |
Abbott Biotherapeutics Corp. |
Anti-her2 antibodies and their uses
|
HUE029026T2
(en)
|
2009-12-22 |
2017-01-30 |
Roche Glycart Ag |
Anti-HER3 antibodies and their applications
|
RU2606264C2
(ru)
*
|
2009-12-25 |
2017-01-10 |
Чугаи Сеияку Кабушики Каиша |
Способ полипептидной модификации для очистки полипептидных мультимеров
|
JP5889181B2
(ja)
|
2010-03-04 |
2016-03-22 |
中外製薬株式会社 |
抗体定常領域改変体
|
US8802091B2
(en)
|
2010-03-04 |
2014-08-12 |
Macrogenics, Inc. |
Antibodies reactive with B7-H3 and uses thereof
|
US9616120B2
(en)
|
2010-03-04 |
2017-04-11 |
Vet Therapeutics, Inc. |
Monoclonal antibodies directed to CD20
|
EP2542258A4
(en)
*
|
2010-03-04 |
2013-08-21 |
Vet Therapeutics Inc |
MONOCLONAL ANTIBODIES DIRECTED AGAINST CD52
|
CA2791658C
(en)
|
2010-03-04 |
2019-10-01 |
Macrogenics, Inc. |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
KR20130049775A
(ko)
|
2010-03-12 |
2013-05-14 |
애브비 바이오테라퓨틱스 인크. |
Ctla4 단백질 및 이의 용도
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
MX341925B
(es)
|
2010-03-29 |
2016-09-07 |
Zymeworks Inc |
Anticuerpos con funcion efectora suprimida o mejorada.
|
EP2563391B1
(en)
|
2010-04-27 |
2020-08-26 |
Roche Glycart AG |
Combination therapy of an afucosylated cd20 antibody with a mtor inhibitor
|
EP2409989A1
(en)
|
2010-07-19 |
2012-01-25 |
International-Drug-Development-Biotech |
Method to improve glycosylation profile for antibody
|
EP2409993A1
(en)
|
2010-07-19 |
2012-01-25 |
International-Drug-Development-Biotech |
Anti-CD19 antibody having ADCC function with improved glycosylation profile
|
EP2409712A1
(en)
|
2010-07-19 |
2012-01-25 |
International-Drug-Development-Biotech |
Anti-CD19 antibody having ADCC and CDC functions and improved glycosylation profile
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
CN103168104B
(zh)
|
2010-07-22 |
2016-09-28 |
加利福尼亚大学董事会 |
抗肿瘤抗原抗体及其使用方法
|
JP5964300B2
(ja)
|
2010-08-02 |
2016-08-03 |
マクロジェニクス,インコーポレーテッド |
共有結合型ダイアボディおよびその使用
|
TW201208703A
(en)
|
2010-08-17 |
2012-03-01 |
Roche Glycart Ag |
Combination therapy of an afucosylated CD20 antibody with an anti-VEGF antibody
|
GB201013989D0
(en)
|
2010-08-20 |
2010-10-06 |
Univ Southampton |
Biological materials and methods of using the same
|
CN103068846B9
(zh)
|
2010-08-24 |
2016-09-28 |
弗·哈夫曼-拉罗切有限公司 |
包含二硫键稳定性Fv片段的双特异性抗体
|
WO2012030842A2
(en)
|
2010-09-03 |
2012-03-08 |
Academia Sinica |
Anti-c-met antibody and methods of use thereof
|
RU2013115927A
(ru)
|
2010-09-10 |
2014-10-20 |
Апексиджен, Инк. |
АНТИТЕЛА ПРОТИВ ИЛ-1β И СПОСОБЫ ПРИМЕНЕНИЯ
|
MY166429A
(en)
|
2010-11-17 |
2018-06-26 |
Chugai Pharmaceutical Co Ltd |
Multi-specific antigen-binding molecule having alternative function to function of blood coagulation factor viii
|
SG190727A1
(en)
|
2010-11-30 |
2013-07-31 |
Chugai Pharmaceutical Co Ltd |
Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
|
BR112013013311A2
(pt)
|
2010-11-30 |
2017-09-19 |
Chugai Pharmaceutical Co Ltd |
agente terapêutico de indução de citotoxicidade
|
WO2012080389A1
(en)
|
2010-12-16 |
2012-06-21 |
Roche Glycart Ag |
Combination therapy of an afucosylated cd20 antibody with a mdm2 inhibitor
|
EP2655413B1
(en)
|
2010-12-23 |
2019-01-16 |
F.Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
AU2012205301B2
(en)
|
2011-01-14 |
2017-01-05 |
Redwood Bioscience, Inc. |
Aldehyde-tagged immunoglobulin polypeptides and method of use thereof
|
KR102147548B1
(ko)
|
2011-02-25 |
2020-08-24 |
추가이 세이야쿠 가부시키가이샤 |
FcγRIIb 특이적 Fc 항체
|
EP2681240B1
(en)
|
2011-02-28 |
2017-08-16 |
F. Hoffmann-La Roche AG |
Monovalent antigen binding proteins
|
EP2681239B8
(en)
|
2011-02-28 |
2015-09-09 |
F. Hoffmann-La Roche AG |
Antigen binding proteins
|
MX342810B
(es)
|
2011-03-03 |
2016-10-13 |
Apexigen Inc |
Anticuerpos del receptor anti-interleucina-6 (anti-il-6) y sus metodos de uso.
|
AU2012225246B2
(en)
|
2011-03-10 |
2016-01-21 |
Omeros Corporation |
Generation of anti-FN14 monoclonal antibodies by ex-vivo accelerated antibody evolution
|
EP3590965A1
(en)
|
2011-03-29 |
2020-01-08 |
Roche Glycart AG |
Antibody fc variants
|
KR20140059168A
(ko)
|
2011-04-21 |
2014-05-15 |
더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 |
시신경 척수염 치료용 조성물 및 치료 방법
|
MX339239B
(es)
|
2011-04-29 |
2016-05-18 |
Apexigen Inc |
Anticuerpos anti-cd40 y metodos de uso.
|
UA117072C2
(uk)
|
2011-05-21 |
2018-06-11 |
Макродженікс, Інк. |
Cd3-зв'язувальна молекула, здатна до зв'язування з cd3 людини, і cd3, що не є людським
|
JP6145088B2
(ja)
|
2011-05-21 |
2017-06-07 |
マクロジェニクス,インコーポレーテッド |
脱免疫化血清結合ドメイン及び血清半減期を延長するためのその使用
|
TWI687441B
(zh)
*
|
2011-06-30 |
2020-03-11 |
中外製藥股份有限公司 |
異源二聚化多胜肽
|
EP3783028A1
(en)
|
2011-08-12 |
2021-02-24 |
Omeros Corporation |
Anti-fzd10 monoclonal antibodies and methods for their use
|
KR101684750B1
(ko)
|
2011-09-23 |
2016-12-08 |
로슈 글리카트 아게 |
이중특이적 항-egfr/항-igf-1r 항체
|
JP6322411B2
(ja)
|
2011-09-30 |
2018-05-09 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
TW201817745A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之FcRn結合域的治療性抗原結合分子
|
TWI827333B
(zh)
*
|
2011-09-30 |
2023-12-21 |
日商中外製藥股份有限公司 |
促進抗原消失的抗原結合分子
|
KR102366029B1
(ko)
|
2011-09-30 |
2022-02-23 |
추가이 세이야쿠 가부시키가이샤 |
표적 항원에 대한 면역응답을 유도하는 항원 결합 분자
|
US10851178B2
(en)
*
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
TWI571473B
(zh)
|
2011-11-02 |
2017-02-21 |
埃派斯進有限公司 |
抗kdr抗體及使用方法
|
US20130302274A1
(en)
|
2011-11-25 |
2013-11-14 |
Roche Glycart Ag |
Combination therapy
|
EP3517550A1
(en)
|
2011-11-30 |
2019-07-31 |
Chugai Seiyaku Kabushiki Kaisha |
Drug containing carrier into cell for forming immune complex
|
TWI593705B
(zh)
|
2011-12-28 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Humanized anti-epiregulin antibody and cancer therapeutic agent containing the antibody as an active ingredient
|
US10577416B2
(en)
|
2012-02-07 |
2020-03-03 |
Innate Pharma, S.A. |
Mica binding agents
|
BR112014019579A2
(pt)
|
2012-02-10 |
2019-10-15 |
Genentech, Inc |
Anticorpo de cadeia única, polinucleotídeo, vetor, célula hospedeira, método de produção de um anticorpo de cadeia única, heteromultímero e método de produção do heteromultímero
|
US9676857B2
(en)
|
2012-03-16 |
2017-06-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Soluble engineered monomeric Fc
|
EP2832856A4
(en)
|
2012-03-29 |
2016-01-27 |
Chugai Pharmaceutical Co Ltd |
ANTI-LAMP5 ANTIBODIES AND USE THEREOF
|
MX360368B
(es)
|
2012-04-27 |
2018-10-29 |
Bioatla Llc |
Regiones de anticuerpo modificado y sus usos.
|
WO2013166290A1
(en)
|
2012-05-04 |
2013-11-07 |
Abbvie Biotherapeutics Inc. |
P21 biomarker assay
|
KR20150013503A
(ko)
*
|
2012-05-11 |
2015-02-05 |
머크 샤프 앤드 돔 코포레이션 |
표면 앵커링된 경쇄 미끼 항체 디스플레이 시스템
|
WO2013177386A1
(en)
|
2012-05-24 |
2013-11-28 |
Abbvie Biotherapeutics Inc. |
Biomarkers for predicting response to tweak receptor (tweakr) agonist therapy
|
CA2869529A1
(en)
|
2012-05-24 |
2013-11-28 |
Raffaella CASTOLDI |
Multispecific antibodies
|
JPWO2013180200A1
(ja)
|
2012-05-30 |
2016-01-21 |
中外製薬株式会社 |
標的組織特異的抗原結合分子
|
EP2857419B1
(en)
|
2012-05-30 |
2021-01-13 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule for eliminating aggregated antigens
|
JP6628966B2
(ja)
|
2012-06-14 |
2020-01-15 |
中外製薬株式会社 |
改変されたFc領域を含む抗原結合分子
|
JP2015531748A
(ja)
|
2012-06-21 |
2015-11-05 |
インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション |
改変fcエフェクター機能を有するインクレチン受容体リガンドポリペプチドfc領域融合ポリペプチド及び複合物
|
RU2639287C2
(ru)
|
2012-06-27 |
2017-12-20 |
Ф. Хоффманн-Ля Рош Аг |
Способ отбора и получения высокоселективных и мультиспецифичных нацеливающих групп с заданными свойствами, включающих по меньшей мере две различные связывающие группировки, и их применения
|
WO2014001325A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
|
EP2684896A1
(en)
|
2012-07-09 |
2014-01-15 |
International-Drug-Development-Biotech |
Anti-DR5 family antibodies, bispecific or multivalent anti-DR5 family antibodies and methods of use thereof
|
JP6154900B2
(ja)
|
2012-07-13 |
2017-06-28 |
ロシュ グリクアート アクチェンゲゼルシャフト |
二重特異性抗vegf/抗ang−2抗体及び眼血管疾患の処置におけるそれらの使用
|
TWI697501B
(zh)
|
2012-08-24 |
2020-07-01 |
日商中外製藥股份有限公司 |
FcγRIIb特異性Fc區域變異體
|
SG11201502094TA
(en)
|
2012-09-19 |
2015-04-29 |
Abbvie Biotherapeutics Inc |
Methods for identifying antibodies with reduced immunogenicity
|
NO2760138T3
(US20060134709A1-20060622-C00021.png)
|
2012-10-01 |
2018-08-04 |
|
|
CN104918957B
(zh)
|
2012-10-30 |
2018-11-16 |
埃派斯进有限公司 |
抗-cd40抗体及其使用方法
|
US20140154255A1
(en)
|
2012-11-30 |
2014-06-05 |
Abbvie Biotherapeutics Inc. |
Anti-vegf antibodies and their uses
|
EP2925779A1
(en)
|
2012-11-30 |
2015-10-07 |
Institut Pasteur |
Use of anti-fcyri and/or anti-fcyriia antibodies for treating arthritis, inflammation, thrombocytopenia and allergic shock
|
US10279018B2
(en)
*
|
2012-12-03 |
2019-05-07 |
Unity Biotechnology, Inc. |
Immunogenic compositions for inducing an immune response for elimination of senescent cells
|
EP3557260B1
(en)
|
2012-12-21 |
2022-05-18 |
Chugai Seiyaku Kabushiki Kaisha |
Gpc3-targeting drug which is administered to patient responsive to gpc3-targeting drug therapy
|
TWI693073B
(zh)
|
2012-12-21 |
2020-05-11 |
日商中外製藥股份有限公司 |
對gpc3標的治療劑療法為有效之患者投與的gpc3標的治療劑
|
CN105102618B
(zh)
*
|
2012-12-27 |
2018-04-17 |
中外制药株式会社 |
异源二聚化多肽
|
US9180185B2
(en)
|
2013-01-11 |
2015-11-10 |
Hoffman-La Roche Inc. |
Combination therapy of anti-HER3 antibodies
|
PT2953976T
(pt)
|
2013-02-08 |
2021-06-23 |
Novartis Ag |
Sítios específicos de modificação de anticorpos para preparar imunoconjugados
|
US10344087B2
(en)
|
2013-02-14 |
2019-07-09 |
Innate Pharma |
Treatment of peripheral T cell lymphoma
|
ES2730011T3
(es)
|
2013-02-20 |
2019-11-07 |
Innate Pharma |
Un compuesto que se une específicamente a KIR3DL2 para el uso en el tratamiento de linfoma de células T periférico
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
WO2014159940A1
(en)
|
2013-03-14 |
2014-10-02 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells that express an activating receptor
|
EP2970436B1
(en)
*
|
2013-03-15 |
2018-09-05 |
AbbVie Biotherapeutics Inc. |
Fc variants
|
EP3216804A3
(en)
|
2013-03-15 |
2017-12-20 |
AbbVie Biotechnology Ltd. |
Anti-cd25 antibodies and their uses
|
JP2016514690A
(ja)
|
2013-03-15 |
2016-05-23 |
アッヴィ バイオテクノロジー リミテッド |
抗cd25抗体およびそれらの使用
|
WO2014163101A1
(ja)
|
2013-04-02 |
2014-10-09 |
中外製薬株式会社 |
Fc領域改変体
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
AU2014273817B2
(en)
|
2013-05-31 |
2019-03-14 |
Zymeworks Bc Inc. |
Heteromultimers with reduced or silenced effector function
|
JPWO2014208482A1
(ja)
|
2013-06-24 |
2017-02-23 |
中外製薬株式会社 |
ヒト化抗Epiregulin抗体を有効成分として含む腺癌以外の非小細胞肺癌の治療剤
|
UA116479C2
(uk)
|
2013-08-09 |
2018-03-26 |
Макродженікс, Інк. |
БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
|
US11384149B2
(en)
|
2013-08-09 |
2022-07-12 |
Macrogenics, Inc. |
Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof
|
EP2840091A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof
|
EP2839842A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
|
WO2015035044A2
(en)
*
|
2013-09-04 |
2015-03-12 |
Abbvie Biotherapeutics Inc. |
Fc VARIANTS WITH IMPROVED ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
|
KR102441231B1
(ko)
|
2013-09-27 |
2022-09-06 |
추가이 세이야쿠 가부시키가이샤 |
폴리펩티드 이종 다량체의 제조방법
|
WO2015052230A1
(en)
|
2013-10-11 |
2015-04-16 |
F. Hoffmann-La Roche Ag |
Multispecific domain exchanged common variable light chain antibodies
|
WO2015082446A1
(en)
|
2013-12-02 |
2015-06-11 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using an anti-cdcp1 antibody and a taxane
|
JP7060317B2
(ja)
|
2013-12-04 |
2022-04-26 |
中外製薬株式会社 |
化合物の濃度に応じて抗原結合能の変化する抗原結合分子及びそのライブラリ
|
WO2015108967A2
(en)
*
|
2014-01-15 |
2015-07-23 |
Medimmune, Llc |
Rsv-specific antibodies and functional parts thereof
|
CN106604740A
(zh)
|
2014-02-14 |
2017-04-26 |
宏观基因有限公司 |
用于治疗血管化癌症的改进的方法
|
MX2016011748A
(es)
|
2014-03-14 |
2016-12-12 |
Innate Pharma |
Anticuerpos humanizados con estabilidad incrementada.
|
UA117289C2
(uk)
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
EP3141603A4
(en)
|
2014-05-08 |
2017-12-27 |
Chugai Seiyaku Kabushiki Kaisha |
Gpc3-targeted therapeutic agent for administration to patients for whom gpc3-targeted therapeutic agent therapy is effective
|
WO2015171847A2
(en)
*
|
2014-05-09 |
2015-11-12 |
One Lambda |
MODIFIED FC GAMMA RECEPTOR TYPE III (FCγIII, HNA-1) POLYPEPTIDES AND THE USES THEREOF
|
CA2947605A1
(en)
|
2014-05-13 |
2015-11-19 |
Bioatla, Llc |
Conditionally active biological proteins
|
GB2526139A
(en)
*
|
2014-05-15 |
2015-11-18 |
Biolnvent Internat Ab |
Medicaments, uses and methods
|
EP3148580B1
(en)
|
2014-05-29 |
2021-01-20 |
MacroGenics, Inc. |
Tri-specific binding molecules that specifically bind to multiple cancer antigens and methods of use thereof
|
AU2015266664B2
(en)
|
2014-05-30 |
2020-04-30 |
Shanghai Henlius Biotech, Inc. |
Anti-epidermal growth factor receptor (EGFR) antibodies
|
AU2015271749B2
(en)
|
2014-06-03 |
2018-03-01 |
Xbiotech Inc. |
Compositions and methods for treating and preventing Staphylococcus aureus infections
|
JP6702893B2
(ja)
|
2014-06-27 |
2020-06-03 |
イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. |
多重特異的抗原結合タンパク質
|
CA2952727A1
(en)
|
2014-06-27 |
2015-12-30 |
Innate Pharma |
Multispecific nkp46 binding proteins
|
US10526391B2
(en)
|
2014-07-22 |
2020-01-07 |
The University Of Notre Dame Du Lac |
Molecular constructs and uses thereof
|
WO2016030488A1
(en)
|
2014-08-27 |
2016-03-03 |
Innate Pharma |
Treatment of celiac disease
|
WO2016044745A1
(en)
|
2014-09-19 |
2016-03-24 |
Regeneron Pharmaceuticals, Inc. |
Chimeric antigen receptors
|
EP3201227A4
(en)
|
2014-09-29 |
2018-04-18 |
Duke University |
Bispecific molecules comprising an hiv-1 envelope targeting arm
|
CN107073116A
(zh)
|
2014-10-23 |
2017-08-18 |
依奈特制药公司 |
使用抗nkg2a试剂治疗癌症
|
AU2015339012B2
(en)
|
2014-10-31 |
2020-11-05 |
Abbvie Biotherapeutics Inc. |
Anti-CS1 antibodies and antibody drug conjugates
|
ES2764111T3
(es)
|
2014-12-03 |
2020-06-02 |
Hoffmann La Roche |
Anticuerpos multiespecíficos
|
US20160158377A1
(en)
|
2014-12-09 |
2016-06-09 |
Abbvie Inc. |
BCL-XL Inhibitory Compounds and Antibody Drug Conjugates Including the Same
|
RU2017123942A
(ru)
|
2014-12-09 |
2019-01-11 |
Эббви Инк. |
Ингибирующие bcl-xl соединения, обладающие низкой клеточной проницаемостью, и коньюгаты антитело-лекарственное средство, включающие их
|
CN113209306A
(zh)
|
2014-12-09 |
2021-08-06 |
艾伯维公司 |
具有细胞渗透性的bcl-xl抑制剂的抗体药物缀合物
|
TWI808330B
(zh)
|
2014-12-19 |
2023-07-11 |
日商中外製藥股份有限公司 |
抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法
|
EP3048116A1
(en)
|
2015-01-23 |
2016-07-27 |
International-Drug-Development-Biotech |
Anti-dr5 antibodies with enhanced apoptosis potency
|
TW202248212A
(zh)
|
2015-02-05 |
2022-12-16 |
日商中外製藥股份有限公司 |
包含離子濃度依賴之抗原結合域的抗體、Fc區變體、IL-8結合抗體與其用途
|
JP6724023B2
(ja)
|
2015-02-09 |
2020-07-15 |
リサーチ ディベロップメント ファウンデーション |
改善された補体活性化を示す操作された免疫グロブリンfcポリペプチド
|
TW202339800A
(zh)
|
2015-02-27 |
2023-10-16 |
日商中外製藥股份有限公司 |
Il-6受體抗體用於製備醫藥組成物的用途
|
JP6773679B2
(ja)
*
|
2015-03-30 |
2020-10-21 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
Fcガンマ受容体に対する結合が低下した重鎖定常領域
|
EP3279216A4
(en)
|
2015-04-01 |
2019-06-19 |
Chugai Seiyaku Kabushiki Kaisha |
PROCESS FOR PREPARING POLYPEPTIDE HETERO OLIGOMER
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
TW201709929A
(zh)
|
2015-06-12 |
2017-03-16 |
宏觀基因股份有限公司 |
治療癌症的聯合療法
|
JP6840682B2
(ja)
|
2015-06-23 |
2021-03-10 |
イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. |
多重特異的抗原結合タンパク質
|
US10113003B2
(en)
|
2015-06-23 |
2018-10-30 |
Innate Pharma |
Multispecific NK engager proteins
|
EP3108897A1
(en)
|
2015-06-24 |
2016-12-28 |
F. Hoffmann-La Roche AG |
Antibodies against human csf-1r for use in inducing lymphocytosis in lymphomas or leukemias
|
PT3328419T
(pt)
|
2015-07-30 |
2021-11-26 |
Macrogenics Inc |
Moléculas de ligação pd-1 e métodos de utilização
|
PE20181336A1
(es)
|
2015-09-18 |
2018-08-21 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos que se unen a interleucina 8 (il-8) y sus usos
|
RU2731202C2
(ru)
|
2015-10-08 |
2020-08-31 |
Макродженикс, Инк. |
Комбинированная терапия для лечения рака
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
SG11201804839WA
(en)
|
2015-12-14 |
2018-07-30 |
Macrogenics Inc |
Bispecific molecules having immunoreactivity with pd-1 and ctla-4, and methods of use thereof
|
EP3394098A4
(en)
|
2015-12-25 |
2019-11-13 |
Chugai Seiyaku Kabushiki Kaisha |
ANTI-MYOSTATIN ANTIBODIES AND METHODS OF USE
|
AU2016381992B2
(en)
|
2015-12-28 |
2024-01-04 |
Chugai Seiyaku Kabushiki Kaisha |
Method for promoting efficiency of purification of Fc region-containing polypeptide
|
EP3423491A1
(en)
|
2016-03-01 |
2019-01-09 |
H. Hoffnabb-La Roche Ag |
Obinutuzumab variants having altered cell death induction
|
RU2018128215A
(ru)
|
2016-03-15 |
2020-04-15 |
Иннейт Фарма |
Антитела против mica
|
EP3430054B1
(en)
|
2016-03-15 |
2021-12-29 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of treating cancers using pd-1 axis binding antagonists and anti-gpc3 antibodies
|
SG11201808979UA
(en)
|
2016-04-15 |
2018-11-29 |
Macrogenics Inc |
Novel b7-h3 binding molecules, antibody drug conjugates thereof and methods of use thereof
|
AU2017257504A1
(en)
|
2016-04-26 |
2018-10-25 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
EP3464362B1
(en)
|
2016-05-27 |
2020-12-09 |
AbbVie Biotherapeutics Inc. |
Anti-4-1bb antibodies and their uses
|
MX2018014630A
(es)
|
2016-05-27 |
2019-06-10 |
Abbvie Biotherapeutics Inc |
Anticuerpos anti-cd40 y sus usos.
|
JP7053499B2
(ja)
|
2016-06-03 |
2022-04-12 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
外因性ターミナルデオキシヌクレオチジルトランスフェラーゼを発現する非ヒト動物
|
EP3835322A3
(en)
|
2016-06-08 |
2021-10-06 |
AbbVie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
EP3257866A1
(en)
|
2016-06-17 |
2017-12-20 |
Academisch Medisch Centrum |
Modified anti-tnf antibody and use thereof in the treatment of ibd
|
EP3494991A4
(en)
|
2016-08-05 |
2020-07-29 |
Chugai Seiyaku Kabushiki Kaisha |
COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATING TO IL-8
|
MX2019002946A
(es)
|
2016-09-14 |
2019-09-26 |
Abbvie Biotherapeutics Inc |
Anticuerpos anti-pd-1 y sus usos.
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
CN110214148A
(zh)
|
2016-10-14 |
2019-09-06 |
Xencor股份有限公司 |
含有IL-15/IL-15Rα Fc融合蛋白和PD-1抗体片段的双特异性异源二聚体融合蛋白
|
US20190248895A1
(en)
|
2016-10-21 |
2019-08-15 |
Innate Pharma |
Treatment with anti-kir3dl2 agents
|
SG10201914126RA
(en)
|
2016-12-15 |
2020-02-27 |
Abbvie Biotherapeutics Inc |
Anti-ox40 antibodies and their uses
|
WO2018115262A1
(en)
|
2016-12-23 |
2018-06-28 |
Innate Pharma |
Heterodimeric antigen binding proteins
|
US11649288B2
(en)
|
2017-02-07 |
2023-05-16 |
Seattle Children's Hospital |
Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
|
SG11201907288RA
(en)
|
2017-02-28 |
2019-09-27 |
Seattle Genetics Inc |
Cysteine mutated antibodies for conjugation
|
WO2018160622A1
(en)
|
2017-02-28 |
2018-09-07 |
Endocyte, Inc. |
Compositions and methods for car t cell therapy
|
US10767164B2
(en)
|
2017-03-30 |
2020-09-08 |
The Research Foundation For The State University Of New York |
Microenvironments for self-assembly of islet organoids from stem cells differentiation
|
US11851486B2
(en)
|
2017-05-02 |
2023-12-26 |
National Center Of Neurology And Psychiatry |
Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils
|
MA49517A
(fr)
|
2017-06-30 |
2020-05-06 |
Xencor Inc |
Protéines de fusion fc hétérodimères ciblées contenant il-15/il-15ra et domaines de liaison à l'antigène
|
CN110945028B
(zh)
|
2017-07-10 |
2023-09-08 |
国际药物发展生物技术公司 |
用非岩藻糖基化促凋亡抗cd19抗体与抗cd20抗体或化疗剂联合治疗b细胞恶性肿瘤
|
CN107748259A
(zh)
*
|
2017-07-26 |
2018-03-02 |
东曜药业有限公司 |
一种FcRn受体的ELISA检测方法
|
CN111032688A
(zh)
|
2017-08-11 |
2020-04-17 |
研究发展基金会 |
用于延长的血清半衰期的工程化抗体fc变体
|
US20200216542A1
(en)
|
2017-09-20 |
2020-07-09 |
Chugai Seiyaku Kabushiki Kaisha |
Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
|
JP7356727B2
(ja)
|
2017-10-12 |
2023-10-05 |
慶應義塾 |
アクアポリン3(aqp3)の細胞外ドメインに特異的に結合する抗aqp3モノクローナル抗体、及びその使用
|
AU2018371114A1
(en)
|
2017-11-21 |
2020-05-07 |
Innate Pharma |
Multispecific antigen binding proteins
|
EP3732201A4
(en)
|
2017-12-19 |
2022-04-20 |
Surrozen Operating, Inc. |
WNT SUBSTITUTION MOLECULES AND THEIR USES
|
CN111699003B
(zh)
|
2017-12-19 |
2024-05-03 |
瑟罗泽恩奥普瑞汀公司 |
抗lrp5/6抗体和使用方法
|
WO2019143837A1
(en)
|
2018-01-17 |
2019-07-25 |
Apexigen, Inc. |
Anti-pd-l1 antibodies and methods of use
|
US11311576B2
(en)
|
2018-01-22 |
2022-04-26 |
Seattle Children's Hospital |
Methods of use for CAR T cells
|
TWI827585B
(zh)
|
2018-03-15 |
2024-01-01 |
日商中外製藥股份有限公司 |
對茲卡病毒具有交叉反應性的抗登革病毒抗體及其使用方法
|
MA52177A
(fr)
|
2018-03-26 |
2021-02-17 |
Regeneron Pharma |
Rongeurs humanisés pour tester des agents thérapeutiques
|
CN112437777A
(zh)
|
2018-04-18 |
2021-03-02 |
Xencor股份有限公司 |
包含IL-15/IL-15RA Fc融合蛋白和TIM-3抗原结合结构域的靶向TIM-3的异源二聚体融合蛋白
|
EP3781599A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
AU2019281358A1
(en)
|
2018-06-03 |
2021-01-07 |
Lamkap Bio Beta Ltd. |
Bispecific antibodies against CEACAM5 and CD47
|
CA3107596A1
(en)
|
2018-08-23 |
2020-02-27 |
Seagen Inc. |
Anti-tigit antibodies
|
JP2021535142A
(ja)
|
2018-08-31 |
2021-12-16 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
Cd3/c20二重特異性抗体のサイトカイン放出症候群を軽減する投与戦略
|
MX2021004059A
(es)
|
2018-10-12 |
2021-09-23 |
Xencor Inc |
Proteínas de fusión de il-15/il-15ralfa-fc dirigidas a pd-1 y usos de las mismas en terapias combinadas.
|
CN113438961A
(zh)
|
2018-12-20 |
2021-09-24 |
Xencor股份有限公司 |
含有IL-15/IL-15Rα和NKG2D抗原结合结构域的靶向异二聚体Fc融合蛋白
|
KR20210119454A
(ko)
|
2019-01-22 |
2021-10-05 |
이나뜨 파르마 에스.에이. |
T 세포 림프종의 치료
|
US20220098307A1
(en)
*
|
2019-02-22 |
2022-03-31 |
Wuhan Yzy Biopharma Co., Ltd. |
Modified fc fragment, antibody comprising same, and application thereof
|
EP3943108A4
(en)
|
2019-03-19 |
2023-01-04 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN-BINDING MOLECULE CONTAINING AN ANTIGEN-BINDING DOMAIN WHOSE ANTIGEN-BINDING ACTIVITY IS ALTERED DEPENDING ON THE MTA, AND BANK FOR OBTAINING SUCH ANTIGEN-BINDING DOMAIN
|
WO2020213084A1
(en)
|
2019-04-17 |
2020-10-22 |
Keio University |
Anti aqp3 monoclonal antibody specifically binding to extracellular domain of aquaporin 3 (aqp3) and use thereof
|
KR20220059481A
(ko)
|
2019-08-07 |
2022-05-10 |
라쿠텐 메디칼, 인크. |
세툭시맙-ir700 접합체 조성물
|
US20240058466A1
(en)
|
2019-10-04 |
2024-02-22 |
TAE Life Sciences |
Antibody Compositions Comprising Fc Mutations and Site-Specific Conjugation Properties For Use In Treating Cancer, Immunological Disorders, and Methods Thereof
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
EP3825330A1
(en)
|
2019-11-19 |
2021-05-26 |
International-Drug-Development-Biotech |
Anti-cd117 antibodies and methods of use thereof
|
EP3831849A1
(en)
|
2019-12-02 |
2021-06-09 |
LamKap Bio beta AG |
Bispecific antibodies against ceacam5 and cd47
|
US20230090552A1
(en)
|
2020-01-08 |
2023-03-23 |
Synthis Therapeutics, Inc. |
Alk5 inhibitor conjugates and uses thereof
|
TW202140553A
(zh)
|
2020-01-13 |
2021-11-01 |
美商威特拉公司 |
C5ar1抗體分子及其用途
|
CN115427447A
(zh)
|
2020-01-17 |
2022-12-02 |
百进生物科技公司 |
抗tlr7药剂和组合物以及制备和使用其的方法
|
CN115315446A
(zh)
|
2020-03-06 |
2022-11-08 |
Go医疗股份有限公司 |
抗糖-cd44抗体及其用途
|
US20230183353A1
(en)
*
|
2020-05-21 |
2023-06-15 |
Zydus Lifesciences Limited |
Fc variant and preparation thereof
|
EP3915641A1
(en)
|
2020-05-27 |
2021-12-01 |
International-Drug-Development-Biotech |
Anti-cd5 antibodies and methods of use thereof
|
AR122983A1
(es)
|
2020-07-16 |
2022-10-19 |
Abbvie Inc |
ANTICUERPOS ANTI-a4b7
|
WO2022093641A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2a agents and compositions and methods for making and using the same
|
WO2022093640A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2c agents and compositions and methods for making and using the same
|
WO2022097065A2
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
ANTIBODY Fc VARIANTS
|
IL301701A
(en)
|
2020-12-18 |
2023-05-01 |
Lamkap Bio Beta Ag |
Bispecific antibodies against CEACAM5 and CD47
|
EP4277931A1
(en)
|
2021-01-13 |
2023-11-22 |
Visterra, Inc. |
Humanized complement 5a receptor 1 antibodies and methods of use thereof
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
JP2024512324A
(ja)
|
2021-03-05 |
2024-03-19 |
ジーオー セラピューティクス,インコーポレイテッド |
抗グリコcd44抗体およびその使用
|
WO2022200525A1
(en)
|
2021-03-26 |
2022-09-29 |
Innate Pharma |
Multispecific proteins comprising an nkp46-binding site, a cancer antgienge binding site fused to a cytokine for nk cell engaging
|
EP4352098A1
(en)
|
2021-06-09 |
2024-04-17 |
Innate Pharma |
Multispecific proteins binding to nkp46, a cytokine receptor, a tumour antigen and cd16a
|
IL308531A
(en)
|
2021-06-09 |
2024-01-01 |
Innate Pharma |
Multiple specific antibodies that bind to CD20, NKP46, CD16 and are equipped with IL-2
|
WO2022258691A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a
|
WO2022258678A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a
|
AR126578A1
(es)
|
2021-07-27 |
2023-10-25 |
Abbvie Inc |
Anticuerpos anti-ccr8
|
CA3226537A1
(en)
|
2021-07-29 |
2023-02-02 |
Ana HENNINO |
Humanized anti-human .beta.ig-h3 protein and uses thereof
|
CA3228178A1
(en)
|
2021-08-05 |
2023-02-09 |
Go Therapeutics, Inc. |
Anti-glyco-muc4 antibodies and their uses
|
TW202325733A
(zh)
|
2021-09-03 |
2023-07-01 |
美商Go治療公司 |
抗醣化-lamp1抗體及其用途
|
AU2022339667A1
(en)
|
2021-09-03 |
2024-04-11 |
Go Therapeutics, Inc. |
Anti-glyco-cmet antibodies and their uses
|
WO2023073599A1
(en)
|
2021-10-28 |
2023-05-04 |
Novartis Ag |
Engineered fc variants
|
WO2023078436A1
(en)
*
|
2021-11-08 |
2023-05-11 |
Acroimmune Guangzhou Biotech Ltd |
Fusion proteins comprising 072 core peptide and use thereof
|
WO2023205659A2
(en)
*
|
2022-04-19 |
2023-10-26 |
Augment Biologics, Inc. |
Glycoengineered antibodies
|
WO2023209568A1
(en)
|
2022-04-26 |
2023-11-02 |
Novartis Ag |
Multispecific antibodies targeting il-13 and il-18
|
WO2023245106A1
(en)
|
2022-06-16 |
2023-12-21 |
Abbvie Biotherapeutics Inc. |
Anti-cd19 antibody drug conjugates
|
WO2023242351A1
(en)
|
2022-06-16 |
2023-12-21 |
Lamkap Bio Beta Ag |
Combination therapy of bispecific antibodies against ceacam5 and cd47 and bispecific antibodies against ceacam5 and cd3
|
WO2024020051A1
(en)
|
2022-07-19 |
2024-01-25 |
BioLegend, Inc. |
Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
|
WO2024040114A2
(en)
|
2022-08-18 |
2024-02-22 |
BioLegend, Inc. |
Anti-axl antibodies, antigen-binding fragments thereof and methods for making and using the same
|