CA2122612C - Produits pharmaceutiques antitumoraux et methode de preparation - Google Patents

Produits pharmaceutiques antitumoraux et methode de preparation Download PDF

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Publication number
CA2122612C
CA2122612C CA002122612A CA2122612A CA2122612C CA 2122612 C CA2122612 C CA 2122612C CA 002122612 A CA002122612 A CA 002122612A CA 2122612 A CA2122612 A CA 2122612A CA 2122612 C CA2122612 C CA 2122612C
Authority
CA
Canada
Prior art keywords
ppm
deuterium
water
deuterium content
content
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002122612A
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English (en)
Other versions
CA2122612A1 (fr
Inventor
Gabor Somlyai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HYD Kutato-Fejleszto Kft
Original Assignee
HYD Kutato-Fejleszto Kft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HYD Kutato-Fejleszto Kft filed Critical HYD Kutato-Fejleszto Kft
Publication of CA2122612A1 publication Critical patent/CA2122612A1/fr
Application granted granted Critical
Publication of CA2122612C publication Critical patent/CA2122612C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002122612A 1991-10-31 1992-09-28 Produits pharmaceutiques antitumoraux et methode de preparation Expired - Lifetime CA2122612C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU913437A HU208084B (en) 1991-10-31 1991-10-31 Process for producing compositions suitable for curing tumorous diseases
HU3437/91 1991-10-31
PCT/HU1992/000036 WO1993008794A1 (fr) 1991-10-31 1992-09-28 Produits pharmaceutiques destines a guerir les maladies tumorales, et leur procede de preparation

Publications (2)

Publication Number Publication Date
CA2122612A1 CA2122612A1 (fr) 1993-05-13
CA2122612C true CA2122612C (fr) 2003-02-04

Family

ID=10964023

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002122612A Expired - Lifetime CA2122612C (fr) 1991-10-31 1992-09-28 Produits pharmaceutiques antitumoraux et methode de preparation

Country Status (22)

Country Link
US (1) US5855921A (fr)
JP (1) JP3569916B2 (fr)
KR (1) KR100253874B1 (fr)
CN (1) CN1045162C (fr)
AT (1) AT402692B (fr)
BE (1) BE1006186A3 (fr)
CA (1) CA2122612C (fr)
CH (1) CH685282A5 (fr)
CZ (1) CZ282379B6 (fr)
DE (1) DE4232465B4 (fr)
DK (1) DK170832B1 (fr)
ES (1) ES2077530B1 (fr)
FI (1) FI114010B (fr)
FR (1) FR2683148B1 (fr)
GB (1) GB2276086B (fr)
HU (1) HU208084B (fr)
IT (1) IT1255390B (fr)
LU (1) LU88175A1 (fr)
NL (1) NL194664C (fr)
NO (1) NO307031B1 (fr)
SE (1) SE513624C2 (fr)
WO (1) WO1993008794A1 (fr)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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HU214593B (hu) * 1994-03-23 1998-06-29 HYD Kutató-Fejlesztő Kft. Kozmetikai, higiéniai, valamint szépség- és testápoló készítmények és eljárás azok előállítására
DE4427690A1 (de) * 1994-08-04 1996-02-08 Bogdahn Ulrich Prof Deuterium enthaltende pharmazeutische Zusammensetzung als Zytostatikum oder Tumor-Therapeutikum
HU217418B (hu) * 1995-04-20 2000-01-28 László Kótai Kémiai eljárás alacsony deutériumtartalmú víz előállítására
RU2083210C1 (ru) * 1995-09-13 1997-07-10 Николаева Ирина Сергеевна Средство для профилактической, поддерживающей и восстановительной терапии развивающихся при старении и/или под воздействием патогенных факторов патологий, связанных с дистрофическим и дегенеративными изменениями органов и тканей
US6444238B1 (en) 2000-03-10 2002-09-03 General Cosmetics Corporation Pain relief composition and method of relieving pain
HU226984B1 (en) * 2001-12-12 2010-04-28 Hyd Kutato Fejlesztoe Kft Medical and food products for treating diabetes mellitus and process for producing thereof
AU2003217385B2 (en) * 2002-02-12 2008-09-11 The Regents Of The University Of California Non-invasive method for measuring rates of biosynthesis of biological molecules by label incorporation
WO2004011426A2 (fr) 2002-07-30 2004-02-05 The Regents Of The University Of California Procede de mesure automatique a grande echelle des taux de flux moleculaire proteomique ou organeomique par spectrometrie de masse
WO2004022098A1 (fr) * 2002-09-09 2004-03-18 Borsos Ferenc Eau enrichie en oxygene, traitee dans un champ magnetique et eau lourde
DE60324950D1 (de) * 2002-09-13 2009-01-08 Univ California Verfahren zur messung der geschwindigkeiten des cholesterinrückwärtstransports in vivo als index für anti-artherogenese
CA2504313C (fr) 2002-11-04 2012-01-17 Marc K. Hellerstein Essai de tolerance au glucose deutere ou aux graisses pour la mesure a haute capacite du metabolisme des sucres ou des acides gras dans le corps
JP2004315487A (ja) * 2003-04-17 2004-11-11 Internatl Scient:Kk 重水素減少水（スーパーライトウォーター）を原料とするスポーツドリンクの飲用による筋肉増強、及び製造方法。
RO120171B1 (ro) * 2003-05-23 2005-10-28 Ioan Nedelcu Produse cosmetice şi pentru igienă, procedeu de obţinere şi procedeu de aplicare a acestora
US7262020B2 (en) * 2003-07-03 2007-08-28 The Regents Of The University Of California Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol
RO120505B1 (ro) * 2003-08-13 2006-02-28 Institutul Oncologic Profesor Dr. Al. Trestioreanu Metodă pentru stabilirea in vivo la animale de experienţă, a concentraţiei eficiente de apă sărăcită în deuteriu pentru tratamentul cancerului
US20050202406A1 (en) * 2003-11-25 2005-09-15 The Regents Of The University Of California Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems
WO2005070438A1 (fr) * 2004-01-23 2005-08-04 Igor Anatolievich Pomytkin Composition pharmaceutique comprenant de l'eau appauvrie en isotopes lourds o17 et o8
TW200538738A (en) * 2004-02-20 2005-12-01 Univ California Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
US20050226825A1 (en) * 2004-04-13 2005-10-13 Giampapa Vincent C Topical composition for preventing and treating skin damage caused by UV light exposure
WO2005117566A1 (fr) * 2004-06-03 2005-12-15 Kunihiro Seki Appareil de production d’un aliment a faible concentration de deuterium
RO121676B1 (ro) * 2004-08-18 2008-02-28 Institutul Oncologic "Prof.Dr. Al. Trestioreanu" Metodă de creştere a toleranţei organismului la tratamentul cu citostatice
BRPI0520021A2 (pt) * 2005-02-08 2009-04-14 Woodford Associates Ltd bebidas não alcoólicas enriquecidas com 1h2 16o
PL1846546T3 (pl) * 2005-02-08 2011-09-30 Woodford Associates Ltd Napój alkoholowy wzbogacany w 1H216O
KR100928384B1 (ko) * 2005-03-05 2009-11-23 세르게이 파브로비치 솔로비에프 1h216o가 강화된 화장품 조성물
WO2006098651A1 (fr) * 2005-03-11 2006-09-21 Vada Consulting Limited Compositions servant à désinfecter des surfaces inanimées
WO2006098650A1 (fr) * 2005-03-11 2006-09-21 Vada Consulting Limited Eau pharmaceutique legere, compositions therapeutiques et procedes correspondants
EA012187B1 (ru) * 2005-03-11 2009-08-28 Вада Консалтинг Лимитед Способы для интрадермальной, трансдермальной или трансмукозальной доставки биологически активных веществ
RU2275920C1 (ru) * 2005-04-01 2006-05-10 Игорь Анатольевич Помыткин Способ лечения новообразований
US20060251576A1 (en) * 2005-05-03 2006-11-09 The Regents Of The University Of California Methods for measuring cholesterol metabolism and transport
TW200711660A (en) * 2005-06-10 2007-04-01 Univ California Monitoring two dimensions of diabetes pathogenesis separately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development
US20080299221A1 (en) * 2005-12-12 2008-12-04 Igor Anatolievich Pomytkin Method for Decreasing Postprandial Glucose Excursion
EA014536B1 (ru) * 2005-12-12 2010-12-30 Тимантти Аб Способ лечения метаболического синдрома
US20080292718A1 (en) * 2005-12-12 2008-11-27 Igor Anatolievich Pomytkin Method for Suppression Appetite and Food Intake
HUP0900231A2 (hu) * 2009-04-16 2010-11-29 Hyd Rakkutato Es Gyogyszerfejlesztoe Kft Allergiás betegségek kezelésére, gyógyítására alkalmas készítmények és eljárás azok elõállítására
DE202009018629U1 (de) 2009-04-21 2012-06-11 Renate Rohlf Gesundheitsförderndes flüssiges Nahrungsmittel
US8658236B2 (en) * 2009-08-21 2014-02-25 Deuteria Beverages, Llc Alcoholic compositions having a lowered risk of acetaldehydemia
CN103562199B (zh) * 2011-05-27 2016-03-30 百时美施贵宝公司 作为丙型肝炎病毒抑制剂的掺入氘的三肽
HUP1100290A2 (en) 2011-06-01 2012-12-28 Hyd Rakkutato Es Gyogyszerfejlesztoe Kft Combination compositions for the treatment of proliferative diseases
JP2014526685A (ja) 2011-09-08 2014-10-06 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア 代謝流量測定、画像化、および顕微鏡法
ES2668678T3 (es) 2011-12-07 2018-05-21 Glaxosmithkline Llc Procedimiento de determinación de la masa muscular esquelética corporal total
HUP1200552A2 (en) 2012-09-21 2014-04-28 Hyd Rakkutato Es Gyogyszerfejlesztoe Kft Pharmaceutical compositions for the treatment of high blood pressure
WO2014088441A1 (fr) * 2012-12-03 2014-06-12 Igor Anatolievich Pomytkin Aliment pour la gestion diététique du syndrome d'épuisement professionnel
US9134319B2 (en) 2013-03-15 2015-09-15 The Regents Of The University Of California Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo
CN103462830A (zh) * 2013-09-03 2013-12-25 大连世纪新源技术开发有限公司 超轻水多肽化妆品及其制备方法
WO2016001643A1 (fr) * 2014-06-30 2016-01-07 Mitochondrial Substrate Invention Limited Solutions de substances nutritives pour l'amélioration de la fonction cognitive
RU2601046C1 (ru) * 2015-07-29 2016-10-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кубанский государственный университет" (ФГБОУ ВПО "КубГУ") Способ снижения содержания дейтерия в пищевых сельскохозяйственных культурах
AU2017329108B2 (en) * 2016-09-21 2022-07-07 Botanical Water Technologies Ip Ltd Isotopic compositions
JP7262480B2 (ja) * 2018-01-02 2023-04-21 ボタニカル ウォーター テクノロジーズ アイピー リミテッド 同位体組成物
WO2019174659A1 (fr) 2018-03-15 2019-09-19 Karl Bau Gmbh Procédé et ensemble servant à fabriquer de l'eau à teneur réduite en deutérium
CN112811559A (zh) * 2020-12-30 2021-05-18 江苏奥特泉超轻水饮料有限公司 一种低氘氢水及其制备方法及应用

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Also Published As

Publication number Publication date
CH685282A5 (de) 1995-05-31
FI941979A (fi) 1994-06-29
JPH08501275A (ja) 1996-02-13
BE1006186A3 (fr) 1994-06-07
CA2122612A1 (fr) 1993-05-13
ATA902992A (de) 1996-12-15
DK170832B1 (da) 1996-02-05
ITMI922233A1 (it) 1994-03-28
FR2683148A1 (fr) 1993-05-07
SE9401406D0 (sv) 1994-04-25
NO941590D0 (fr) 1994-04-29
ES2077530A1 (es) 1995-11-16
HU913437D0 (en) 1992-01-28
KR930007461A (ko) 1993-05-20
FI941979A0 (fi) 1994-04-29
HU208084B (en) 1993-08-30
FR2683148B1 (fr) 1994-09-09
NO941590L (fr) 1994-06-23
SE513624C2 (sv) 2000-10-09
DE4232465A1 (de) 1993-05-06
GB2276086A (en) 1994-09-21
CN1071836A (zh) 1993-05-12
NL194664B (nl) 2002-07-01
NL9220026A (nl) 1994-09-01
CZ102094A3 (en) 1994-12-15
DE4232465B4 (de) 2008-11-06
AT402692B (de) 1997-07-25
NL194664C (nl) 2002-11-04
WO1993008794A1 (fr) 1993-05-13
GB2276086B (en) 1995-09-27
IT1255390B (it) 1995-10-31
CN1045162C (zh) 1999-09-22
LU88175A1 (fr) 1993-03-15
CZ282379B6 (cs) 1997-07-16
KR100253874B1 (ko) 2000-04-15
ES2077530B1 (es) 1996-07-01
ITMI922233A0 (it) 1992-09-28
SE9401406L (sv) 1994-06-07
GB9408654D0 (en) 1994-07-20
JP3569916B2 (ja) 2004-09-29
FI114010B (fi) 2004-07-30
NO307031B1 (no) 2000-01-31
US5855921A (en) 1999-01-05

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