CA1128512A - 2-amino-3-benzoyl-phenylacetamides and cyclic homologues - Google Patents
2-amino-3-benzoyl-phenylacetamides and cyclic homologuesInfo
- Publication number
- CA1128512A CA1128512A CA361,068A CA361068A CA1128512A CA 1128512 A CA1128512 A CA 1128512A CA 361068 A CA361068 A CA 361068A CA 1128512 A CA1128512 A CA 1128512A
- Authority
- CA
- Canada
- Prior art keywords
- amino
- compound
- benzoyl
- process according
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7886079A | 1979-09-26 | 1979-09-26 | |
| US078,860 | 1979-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1128512A true CA1128512A (en) | 1982-07-27 |
Family
ID=22146633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA361,068A Expired CA1128512A (en) | 1979-09-26 | 1980-09-25 | 2-amino-3-benzoyl-phenylacetamides and cyclic homologues |
Country Status (36)
| Country | Link |
|---|---|
| JP (1) | JPS5657751A (de) |
| KR (1) | KR840000763B1 (de) |
| AT (1) | AT374170B (de) |
| AU (1) | AU532359B2 (de) |
| BE (1) | BE885393A (de) |
| BR (1) | BR8006042A (de) |
| CA (1) | CA1128512A (de) |
| CH (1) | CH646138A5 (de) |
| CS (1) | CS227012B2 (de) |
| DE (1) | DE3035688A1 (de) |
| DK (1) | DK154136C (de) |
| EG (1) | EG15020A (de) |
| ES (2) | ES495329A0 (de) |
| FI (1) | FI72967C (de) |
| FR (1) | FR2465710A1 (de) |
| GB (1) | GB2059963B (de) |
| GR (1) | GR70049B (de) |
| HK (1) | HK59383A (de) |
| HU (1) | HU183215B (de) |
| IE (1) | IE50268B1 (de) |
| IL (1) | IL60999A (de) |
| IN (3) | IN151313B (de) |
| IT (1) | IT1133823B (de) |
| KE (1) | KE3307A (de) |
| LU (1) | LU82797A1 (de) |
| MX (1) | MX7159E (de) |
| NL (1) | NL8005346A (de) |
| NO (1) | NO152128C (de) |
| NZ (1) | NZ195061A (de) |
| PH (1) | PH22628A (de) |
| PL (1) | PL128998B1 (de) |
| PT (1) | PT71839B (de) |
| SE (1) | SE448626B (de) |
| SG (1) | SG42983G (de) |
| YU (3) | YU41734B (de) |
| ZA (1) | ZA805476B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
| US6066671A (en) * | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
| US6646001B2 (en) | 1997-12-19 | 2003-11-11 | Alcon Manufacturing, Ltd. | Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension |
| GB9727523D0 (en) * | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
| PT1423168E (pt) | 2001-09-03 | 2006-05-31 | Newron Pharm Spa | Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico |
| EP1438956A1 (de) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind |
| CZ2009367A3 (cs) * | 2009-06-08 | 2010-06-16 | Farmak, A.S. | Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu |
| CN112794809B (zh) * | 2019-11-14 | 2023-12-29 | 南京济群医药科技股份有限公司 | 一种高纯度奈帕芬胺中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1226344A (de) * | 1967-07-31 | 1971-03-24 | ||
| SE400966B (sv) * | 1975-08-13 | 1978-04-17 | Robins Co Inc A H | Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror |
| IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
-
1980
- 1980-09-04 ZA ZA00805476A patent/ZA805476B/xx unknown
- 1980-09-08 IL IL60999A patent/IL60999A/xx unknown
- 1980-09-08 AU AU62116/80A patent/AU532359B2/en not_active Ceased
- 1980-09-11 CS CS806196A patent/CS227012B2/cs unknown
- 1980-09-17 IE IE1946/80A patent/IE50268B1/en unknown
- 1980-09-20 EG EG80573A patent/EG15020A/xx active
- 1980-09-22 BR BR8006042A patent/BR8006042A/pt unknown
- 1980-09-22 DE DE19803035688 patent/DE3035688A1/de active Granted
- 1980-09-22 GR GR62936A patent/GR70049B/el unknown
- 1980-09-23 PH PH24613A patent/PH22628A/en unknown
- 1980-09-23 AT AT0474580A patent/AT374170B/de not_active IP Right Cessation
- 1980-09-24 SE SE8006668A patent/SE448626B/sv not_active IP Right Cessation
- 1980-09-24 FI FI803002A patent/FI72967C/fi not_active IP Right Cessation
- 1980-09-24 LU LU82797A patent/LU82797A1/fr unknown
- 1980-09-25 BE BE0/202226A patent/BE885393A/fr not_active IP Right Cessation
- 1980-09-25 MX MX809050U patent/MX7159E/es unknown
- 1980-09-25 PL PL1980226919A patent/PL128998B1/pl unknown
- 1980-09-25 PT PT71839A patent/PT71839B/pt unknown
- 1980-09-25 NL NL8005346A patent/NL8005346A/nl not_active Application Discontinuation
- 1980-09-25 FR FR8020596A patent/FR2465710A1/fr active Granted
- 1980-09-25 DK DK405780A patent/DK154136C/da not_active IP Right Cessation
- 1980-09-25 ES ES495329A patent/ES495329A0/es active Granted
- 1980-09-25 HU HU802347A patent/HU183215B/hu not_active IP Right Cessation
- 1980-09-25 CA CA361,068A patent/CA1128512A/en not_active Expired
- 1980-09-25 CH CH719180A patent/CH646138A5/fr not_active IP Right Cessation
- 1980-09-25 KR KR1019800003740A patent/KR840000763B1/ko active
- 1980-09-25 YU YU2450/80A patent/YU41734B/xx unknown
- 1980-09-25 NO NO802834A patent/NO152128C/no unknown
- 1980-09-25 GB GB8030955A patent/GB2059963B/en not_active Expired
- 1980-09-26 NZ NZ195061A patent/NZ195061A/en unknown
- 1980-09-26 IT IT24948/80A patent/IT1133823B/it active
- 1980-09-26 JP JP13415280A patent/JPS5657751A/ja active Granted
- 1980-09-26 IN IN1092/CAL/80A patent/IN151313B/en unknown
-
1981
- 1981-06-12 ES ES503019A patent/ES503019A0/es active Granted
-
1982
- 1982-12-30 IN IN1508/CAL/82A patent/IN156254B/en unknown
- 1982-12-30 IN IN1509/CAL/82A patent/IN156255B/en unknown
-
1983
- 1983-03-28 YU YU731/83A patent/YU43306B/xx unknown
- 1983-03-28 YU YU730/83A patent/YU43305B/xx unknown
- 1983-07-19 SG SG42983A patent/SG42983G/en unknown
- 1983-07-21 KE KE3307A patent/KE3307A/xx unknown
- 1983-11-24 HK HK593/83A patent/HK59383A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |