BRPI0823506A8 - composições e métodos para a produção de isoprene - Google Patents
composições e métodos para a produção de isoprene Download PDFInfo
- Publication number
- BRPI0823506A8 BRPI0823506A8 BRPI0823506A BRPI0823506A BRPI0823506A8 BR PI0823506 A8 BRPI0823506 A8 BR PI0823506A8 BR PI0823506 A BRPI0823506 A BR PI0823506A BR PI0823506 A BRPI0823506 A BR PI0823506A BR PI0823506 A8 BRPI0823506 A8 BR PI0823506A8
- Authority
- BR
- Brazil
- Prior art keywords
- isoprene
- methods
- compositions
- production
- cultured cells
- Prior art date
Links
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 3
- 210000004748 cultured cell Anatomy 0.000 abstract 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1229—Phosphotransferases with a phosphate group as acceptor (2.7.4)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01009—Acetyl-CoA C-acetyltransferase (2.3.1.9)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01036—Mevalonate kinase (2.7.1.36)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01033—Diphosphomevalonate decarboxylase (4.1.1.33), i.e. mevalonate-pyrophosphate decarboxylase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
- C12Y402/03027—Isoprene synthase (4.2.3.27)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y503/00—Intramolecular oxidoreductases (5.3)
- C12Y503/03—Intramolecular oxidoreductases (5.3) transposing C=C bonds (5.3.3)
- C12Y503/03002—Isopentenyl-diphosphate DELTA-isomerase (5.3.3.2)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1357407P | 2007-12-13 | 2007-12-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0823506A2 BRPI0823506A2 (pt) | 2012-07-10 |
| BRPI0823506A8 true BRPI0823506A8 (pt) | 2018-05-15 |
Family
ID=40756152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0823506A BRPI0823506A8 (pt) | 2007-12-13 | 2008-12-15 | composições e métodos para a produção de isoprene |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US8288148B2 (enExample) |
| EP (2) | EP3354740A1 (enExample) |
| JP (3) | JP6049982B2 (enExample) |
| KR (1) | KR20100118973A (enExample) |
| CN (2) | CN105368764B (enExample) |
| AU (1) | AU2008334945C1 (enExample) |
| BR (1) | BRPI0823506A8 (enExample) |
| CA (1) | CA2709107A1 (enExample) |
| DK (1) | DK2235190T3 (enExample) |
| MX (1) | MX2010006576A (enExample) |
| RU (1) | RU2545699C2 (enExample) |
| SG (2) | SG191671A1 (enExample) |
| WO (1) | WO2009076676A2 (enExample) |
Families Citing this family (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101784653A (zh) | 2007-05-01 | 2010-07-21 | 嗜酸细胞有限责任公司 | 利用代谢改造的光合微生物将二氧化碳直接转化为烃的方法 |
| BRPI0823506A8 (pt) | 2007-12-13 | 2018-05-15 | Danisco Us Inc Genencor Div | composições e métodos para a produção de isoprene |
| JP2011518564A (ja) | 2008-04-23 | 2011-06-30 | ダニスコ・ユーエス・インク | 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体 |
| SG167485A1 (en) * | 2008-06-30 | 2011-01-28 | Danisco Us Inc | Polymers of isoprene from renewable resources |
| EP2310490B1 (en) * | 2008-07-02 | 2019-01-02 | Danisco US Inc. | Methods for producing isoprene |
| MY156562A (en) | 2008-09-15 | 2016-02-26 | Danisco Us Inc | Increased isoprene production using the archaeal lower mevalonate pathway |
| CA2737082A1 (en) * | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using mevalonate kinase and isoprene synthase |
| CA2737223A1 (en) * | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
| WO2010031079A1 (en) * | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Systems using cell culture for production of isoprene |
| CN102333866B (zh) | 2008-12-30 | 2015-04-29 | 丹尼斯科美国公司 | 生产异戊二烯和共同产物的方法 |
| US8324442B2 (en) * | 2009-03-03 | 2012-12-04 | Amyris, Inc. | Microbial derived isoprene and methods for making the same |
| EP2421966A2 (en) | 2009-04-23 | 2012-02-29 | Danisco US Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
| TW201412988A (zh) * | 2009-06-17 | 2014-04-01 | Danisco Us Inc | 使用dxp及mva途徑之改良之異戊二烯製造 |
| TWI434921B (zh) | 2009-06-17 | 2014-04-21 | Danisco Us Inc | 從生物異戊二烯組合物製造燃料成分之方法及系統 |
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| US20110039323A1 (en) * | 2009-08-14 | 2011-02-17 | Eric Lawrence Singsaas | Isoprene Production |
| EP2480660B1 (en) | 2009-09-23 | 2020-08-05 | Danisco US Inc. | Novel glycosyl hydrolase enzymes and uses thereof |
| CN102884028B (zh) | 2009-12-18 | 2015-08-19 | 丹尼斯科美国公司 | 从可再生资源中纯化异戊二烯 |
| AU2009357243B2 (en) | 2009-12-22 | 2014-07-03 | Global Bioenergies | Process for the production of isoprenol from mevalonate employing a diphosphomevalonate decarboxylase |
| CA2785530A1 (en) | 2009-12-22 | 2011-06-23 | Danisco Us Inc. | Membrane bioreactor for increased production of isoprene gas |
| AU2010336342B2 (en) | 2009-12-23 | 2015-02-26 | Danisco Us Inc. | Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (PGL) |
| CN107287250A (zh) | 2009-12-23 | 2017-10-24 | 丹尼斯科美国公司 | 提高同步糖化发酵反应效率的方法 |
| MX336229B (es) * | 2010-05-05 | 2016-01-08 | Genomatica Inc | Microorganismos y metodos para la biosintesis de butadieno. |
| BR112012032276A2 (pt) | 2010-06-17 | 2016-11-16 | Danisco Us Inc | composições de combustível compreendendo derivados de isopreno |
| WO2012019169A1 (en) | 2010-08-06 | 2012-02-09 | Danisco Us Inc. | Production of isoprene under neutral ph conditions |
| JP2014502148A (ja) | 2010-10-27 | 2014-01-30 | ダニスコ・ユーエス・インク | イソプレン生産の向上を目的としたイソプレン合成酵素変異体 |
| CN102559769B (zh) * | 2010-12-20 | 2014-07-30 | 中国科学院青岛生物能源与过程研究所 | 一种制备异戊二烯的重组细胞及其制备方法 |
| WO2012088450A1 (en) | 2010-12-22 | 2012-06-28 | Danisco Us Inc. | Biological production of pentose sugars using recombinant cells |
| EP2655606A1 (en) | 2010-12-22 | 2013-10-30 | Danisco US Inc. | Compositions and methods for improved isoprene production using two types of ispg enzymes |
| WO2012115994A1 (en) * | 2011-02-23 | 2012-08-30 | Syngenta Participations Ag | Potentiation of enzymatic saccharification |
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| EP2686434B1 (en) | 2011-03-17 | 2021-07-14 | Danisco US Inc. | Method for reducing viscosity in saccharification process |
| US9121038B2 (en) * | 2011-04-29 | 2015-09-01 | The Goodyear Tire & Rubber Company | Recombinant microorganisms for enhanced production of mevalonate, isoprene, and isoprenoids |
| JP2014519811A (ja) | 2011-04-29 | 2014-08-21 | ダニスコ・ユーエス・インク | チオラーゼ、HMG−CoA合成酵素及びHMG−CoA還元酵素活性を有するポリペプチドをコードしている遺伝子を使用するメバロン酸、イソプレン、及びイソプレノイドの生産 |
| US9169486B2 (en) | 2011-06-22 | 2015-10-27 | Genomatica, Inc. | Microorganisms for producing butadiene and methods related thereto |
| EP2739728B1 (en) | 2011-08-04 | 2017-07-12 | Novozymes A/S | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| AU2012289886A1 (en) | 2011-08-04 | 2014-02-20 | Danisco Us Inc. | Production of isoprene, isoprenoid precursors, and isoprenoids using acetoacetyl-CoA synthase |
| US8951764B2 (en) | 2011-08-05 | 2015-02-10 | Danisco Us Inc. | Production of isoprenoids under neutral pH conditions |
| WO2013040383A1 (en) * | 2011-09-16 | 2013-03-21 | Genomatica, Inc. | Microorganisms and methods for producing alkenes |
| US20130273625A1 (en) * | 2011-10-07 | 2013-10-17 | Danisco Us Inc. | Methods for increasing microbial production of isoprene, isoprenoids, and isoprenoid precursor molecules using glucose and acetate co-metabolism |
| SG11201401249PA (en) | 2011-10-07 | 2014-05-29 | Danisco Us Inc | Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene |
| WO2013053824A1 (en) | 2011-10-11 | 2013-04-18 | Metabolic Explorer | New biosynthesis pathway for prenol in a recombinant microorganism |
| WO2013063528A2 (en) | 2011-10-27 | 2013-05-02 | Danisco Us Inc. | Isoprene synthase variants with improved solubility for production of isoprene |
| EP2794891A2 (en) | 2011-12-20 | 2014-10-29 | Scientist of Fortune S.A. | Production of 1,3-dienes by enzymatic conversion of 3-hydroxyalk-4-enoates and/or 3-phosphonoxyalk-4-enoates |
| EP2794876A1 (en) | 2011-12-23 | 2014-10-29 | Danisco US Inc. | Production of isoprene under reduced oxygen inlet levels |
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| WO2013096863A1 (en) * | 2011-12-23 | 2013-06-27 | The Regents Of The University Of California | Constructs and methods for improved isoprene biosynthesis |
| US9315831B2 (en) | 2012-03-30 | 2016-04-19 | Danisco Us Inc. | Direct starch to fermentable sugar as feedstock for the production of isoprene, isoprenoid precursor molecules, and/or isoprenoids |
| AU2013244969B2 (en) * | 2012-04-05 | 2017-03-02 | Global Bioenergies | Method for the enzymatic production of isoprenol using mevalonate as a substrate |
| US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
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| KR20150014941A (ko) * | 2012-05-16 | 2015-02-09 | 글리코스 바이오테크놀로지스, 인코포레이티드 | 아이소프렌의 생산을 위한 미생물유기체 및 방법 |
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| US8703455B2 (en) * | 2012-08-29 | 2014-04-22 | Scientist of Fourtune, S.A. | Production of volatile dienes by enzymatic dehydration of light alkenols |
| CN111621453A (zh) | 2012-10-23 | 2020-09-04 | 积水化学工业株式会社 | 重组细胞以及异戊二烯的生产方法 |
| WO2014076232A2 (en) * | 2012-11-19 | 2014-05-22 | Novozymes A/S | Isopropanol production by recombinant hosts using an hmg-coa intermediate |
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| US20160040118A1 (en) * | 2013-03-14 | 2016-02-11 | President And Fellows Of Harvard College | Genetically Modified Bacteria |
| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| RU2662678C2 (ru) | 2013-03-29 | 2018-07-26 | Адзиномото Ко., Инк. | Способ выделения изопрена, содержащегося в полученном в ходе ферментации газе, и способ получения очищенного изопрена |
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| US10648004B2 (en) | 2014-02-20 | 2020-05-12 | Danisco Us Inc. | Recombinant microorganisms for the enhanced production of mevalonate, isoprene, isoprenoid precursors, isoprenoids, and acetyl-CoA-derived products |
| US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
| RU2014112066A (ru) | 2014-03-28 | 2015-10-10 | Адзиномото Ко., Инк. | Способ получения мономерного изопрена |
| WO2016015021A1 (en) | 2014-07-24 | 2016-01-28 | The Regents Of The University Of California | Oxidative starch degradation by a new family of pmos |
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