SG11201403163QA - Enhanced production of isoprene using host cells having decreased ispa activity - Google Patents

Enhanced production of isoprene using host cells having decreased ispa activity

Info

Publication number
SG11201403163QA
SG11201403163QA SG11201403163QA SG11201403163QA SG11201403163QA SG 11201403163Q A SG11201403163Q A SG 11201403163QA SG 11201403163Q A SG11201403163Q A SG 11201403163QA SG 11201403163Q A SG11201403163Q A SG 11201403163QA SG 11201403163Q A SG11201403163Q A SG 11201403163QA
Authority
SG
Singapore
Prior art keywords
isoprene
host cells
enhanced production
activity
decreased
Prior art date
Application number
SG11201403163QA
Inventor
Joseph C Mcauliffe
Rachel E Muir
Alex T Nielsen
Caroline M Peres
Dmitrii V Vaviline
Derek H Wells
Original Assignee
Danisco Us Inc
Goodyear Tire & Rubber
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc, Goodyear Tire & Rubber filed Critical Danisco Us Inc
Publication of SG11201403163QA publication Critical patent/SG11201403163QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y205/00Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01001Dimethylallyltranstransferase (2.5.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/03Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027Isoprene synthase (4.2.3.27)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
SG11201403163QA 2011-12-23 2012-12-21 Enhanced production of isoprene using host cells having decreased ispa activity SG11201403163QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161580163P 2011-12-23 2011-12-23
US201261639855P 2012-04-27 2012-04-27
PCT/US2012/071518 WO2013096925A1 (en) 2011-12-23 2012-12-21 Enhanced production of isoprene using host cells having decreased ispa activity

Publications (1)

Publication Number Publication Date
SG11201403163QA true SG11201403163QA (en) 2014-09-26

Family

ID=47522963

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201403163QA SG11201403163QA (en) 2011-12-23 2012-12-21 Enhanced production of isoprene using host cells having decreased ispa activity

Country Status (10)

Country Link
US (2) US8975051B2 (en)
EP (1) EP2794863A1 (en)
JP (1) JP2015510392A (en)
CN (1) CN104245927A (en)
AU (1) AU2012358149A1 (en)
BR (1) BR112014014947A2 (en)
CA (1) CA2859885A1 (en)
MX (1) MX2014007623A (en)
SG (1) SG11201403163QA (en)
WO (1) WO2013096925A1 (en)

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AU2013304001B2 (en) * 2012-08-17 2019-01-03 Evolva Sa Increased production of terpenes and terpenoids
JP6492011B2 (en) * 2013-12-04 2019-03-27 国立研究開発法人理化学研究所 Production of polyhydroxyalkanoic acid by photosynthesis alone
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
KR102106038B1 (en) 2017-05-11 2020-04-29 경상대학교 산학협력단 Marker composition for transformed organism, transformed organism and method for transformation
WO2018208116A1 (en) * 2017-05-11 2018-11-15 경상대학교산학협력단 Marker composition for selecting living modified organism, living modified organism, and transformation method
CN110317765B (en) * 2018-03-29 2020-11-20 中国科学院天津工业生物技术研究所 Escherichia coli expression strain for high-yield geraniol glucoside and application thereof
US11525148B2 (en) * 2018-11-27 2022-12-13 Khona Scientific Holdings, Inc. Bidirectional multi-enzymatic scaffolds for biosynthesizing cannabinoids
CN112553134B (en) * 2020-12-30 2022-09-06 江南大学 Method for expressing alpha-amylase in bacillus subtilis

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JPWO2003095651A1 (en) 2002-05-10 2005-09-15 協和醗酵工業株式会社 Method for producing mevalonic acid
MXPA05003382A (en) 2002-10-04 2005-06-22 Du Pont Process for the biological production of 1,3-propanediol with high yield.
RU2004124226A (en) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) USE OF PHOSPHOCETHOLASE FOR PRODUCTION OF USEFUL METABOLITES
US7659097B2 (en) 2006-05-26 2010-02-09 Amyris Biotechnologies, Inc. Production of isoprenoids
US7947478B2 (en) 2006-06-29 2011-05-24 The Regents Of The University Of California Short chain volatile hydrocarbon production using genetically engineered microalgae, cyanobacteria or bacteria
JP4986547B2 (en) 2006-09-04 2012-07-25 株式会社Adeka Novel acetoacetyl CoA synthase, DNA sequence encoding the same, method for producing the enzyme, and method for producing mevalonic acid using the enzyme
RU2545699C2 (en) * 2007-12-13 2015-04-10 ДАНИСКО ЮЭс ИНК. Compositions and methods of producing isoprene
WO2009100231A2 (en) 2008-02-06 2009-08-13 The Regents Of The University Of California Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi
RU2516343C2 (en) 2008-04-23 2014-05-20 ДАНИСКО ЮЭс ИНК. Versions of isoprene synthase applied for improvement of isoprene production by microorganisms
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US8361762B2 (en) 2008-09-15 2013-01-29 Danisco Us Inc. Increased isoprene production using the archaeal lower mevalonate pathway
CA2737223A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Reduction of carbon dioxide emission during isoprene production by fermentation
BRPI0918936A2 (en) 2008-09-15 2019-09-24 Danisco Us Inc conversion of prenyl derivatives to isoprene
EP3323881A1 (en) 2008-09-15 2018-05-23 Danisco US Inc. Systems using cell culture for production of isoprene
JP5793424B2 (en) 2008-12-30 2015-10-14 ダニスコ・ユーエス・インク Production method of isoprene and by-products
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TWI434921B (en) 2009-06-17 2014-04-21 Danisco Us Inc Methods and systems for producing fuel constituents from bioisoprene compositions
TWI427149B (en) 2009-06-17 2014-02-21 Danisco Us Inc Improved isoprene production using the dxp and mva pathway
WO2011034863A1 (en) 2009-09-15 2011-03-24 Sapphire Energy, Inc. A system for transformation of the chloroplast genome of scenedesmus sp. and dunaliella sp.
CN102884028B (en) 2009-12-18 2015-08-19 丹尼斯科美国公司 Purification of isoprene from renewable resources
CN102906268A (en) * 2009-12-23 2013-01-30 丹尼斯科美国公司 Compositions and methods for the increased production of isoprene and other products with 6 - phosphogluconolactonase (PGL)
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
WO2012058494A2 (en) 2010-10-27 2012-05-03 Danisco Us Inc. Isoprene synthase variants for improved production of isoprene

Also Published As

Publication number Publication date
WO2013096925A1 (en) 2013-06-27
US9388431B2 (en) 2016-07-12
US20130164808A1 (en) 2013-06-27
BR112014014947A2 (en) 2020-10-27
EP2794863A1 (en) 2014-10-29
JP2015510392A (en) 2015-04-09
US20150218590A1 (en) 2015-08-06
MX2014007623A (en) 2015-02-04
CA2859885A1 (en) 2013-06-27
AU2012358149A1 (en) 2014-07-03
US8975051B2 (en) 2015-03-10
CN104245927A (en) 2014-12-24

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