BRPI0515995A - compostos para supressão sem sentido, e métodos para sua aplicação - Google Patents
compostos para supressão sem sentido, e métodos para sua aplicaçãoInfo
- Publication number
- BRPI0515995A BRPI0515995A BRPI0515995-4A BRPI0515995A BRPI0515995A BR PI0515995 A BRPI0515995 A BR PI0515995A BR PI0515995 A BRPI0515995 A BR PI0515995A BR PI0515995 A BRPI0515995 A BR PI0515995A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- compounds
- application
- senseless
- compositions
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 230000001629 suppression Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 3
- 108020004999 messenger RNA Proteins 0.000 abstract 2
- 108020004485 Nonsense Codon Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000037434 nonsense mutation Effects 0.000 abstract 1
- 230000002028 premature Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
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- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
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- C07D271/107—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with two aryl or substituted aryl radicals attached in positions 2 and 5
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- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
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- C07F9/653—Five-membered rings
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61763304P | 2004-10-13 | 2004-10-13 | |
| US61765504P | 2004-10-13 | 2004-10-13 | |
| US61763404P | 2004-10-13 | 2004-10-13 | |
| US61767004P | 2004-10-13 | 2004-10-13 | |
| US61765304P | 2004-10-13 | 2004-10-13 | |
| US62417004P | 2004-11-03 | 2004-11-03 | |
| PCT/US2005/036761 WO2006044502A2 (en) | 2004-10-13 | 2005-10-13 | Pyrazole or triazole compounds and their use for the manufacture of a medicament for treating somatic mutation-related diseases |
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| BRPI0515995-4A BRPI0515995A (pt) | 2004-10-13 | 2005-10-13 | compostos para supressão sem sentido, e métodos para sua aplicação |
| BRPI0516110-0A BRPI0516110A (pt) | 2004-10-13 | 2005-10-13 | compostos para supressão sem sentido e métodos para seu uso |
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| BRPI0516110-0A BRPI0516110A (pt) | 2004-10-13 | 2005-10-13 | compostos para supressão sem sentido e métodos para seu uso |
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2014
- 2014-04-28 US US14/263,478 patent/US9273076B2/en not_active Expired - Lifetime
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2015
- 2015-06-08 US US14/733,615 patent/US20150274674A1/en not_active Abandoned
-
2016
- 2016-04-15 US US15/130,318 patent/US20160229818A1/en not_active Abandoned
-
2017
- 2017-03-31 US US15/475,240 patent/US20170204073A1/en not_active Abandoned
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