BR112020007576A2 - composições e métodos para degradação de proteína seletiva - Google Patents
composições e métodos para degradação de proteína seletiva Download PDFInfo
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- BR112020007576A2 BR112020007576A2 BR112020007576-0A BR112020007576A BR112020007576A2 BR 112020007576 A2 BR112020007576 A2 BR 112020007576A2 BR 112020007576 A BR112020007576 A BR 112020007576A BR 112020007576 A2 BR112020007576 A2 BR 112020007576A2
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- fusion polypeptide
- crbn
- cof1
- amino acid
- cell
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70517—CD8
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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