BR112014005958A2 - métodos e composições químicas agrícolas para controle de planta, método de redução de expressão de um gene accase em uma planta, cassete de expressão microbiana, método para fazer um polinucleotídeo, método de identificação de polinucleotídeos úteis na modulação de expressão do gene accase e composição herbicida - Google Patents

métodos e composições químicas agrícolas para controle de planta, método de redução de expressão de um gene accase em uma planta, cassete de expressão microbiana, método para fazer um polinucleotídeo, método de identificação de polinucleotídeos úteis na modulação de expressão do gene accase e composição herbicida Download PDF

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BR112014005958A2
BR112014005958A2 BR112014005958-6A BR112014005958A BR112014005958A2 BR 112014005958 A2 BR112014005958 A2 BR 112014005958A2 BR 112014005958 A BR112014005958 A BR 112014005958A BR 112014005958 A2 BR112014005958 A2 BR 112014005958A2
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polynucleotide
herbicides
plant
accase
composition
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Daniel Ader
Matt W. Dimmic
Zhaolong Li
Robert Douglas Sammons
Ronak Hasmukh Shah
Nengbing Tao
Dafu Wang
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Monsanto Technology Llc
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H3/00—Processes for modifying phenotypes, e.g. symbiosis with bacteria
    • A01H3/04—Processes for modifying phenotypes, e.g. symbiosis with bacteria by treatment with chemicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical at least one of the bonds to hetero atoms is to nitrogen
    • A01N35/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical at least one of the bonds to hetero atoms is to nitrogen containing a carbon-to-nitrogen double bond
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A01N57/24—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing heterocyclic radicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
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    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01002—Acetyl-CoA carboxylase (6.4.1.2)

Abstract

métodos e composições quimicas agricolas para controle de planta, método de redução de expressão de um gene accase em uma planta, cassete de expressão microbiana, método para fazer um polinucleotídeo, método de identificação de polinucleotídeos úteis na modulação de expressão do gene accase e composição herbicida a presente invenção provê novas composições para uso para melhorar o controle de ervas daninhas. especificamente, a presente invenção provê métodos e composições que modulam acetil-coa carboxilase em espécies de ervas daninhas. a presente invenção também provê combinações de composições e métodos que melhoram o controle de ervas daninhas.

Description

Relatório Descritivo da Patente de Invenção para "MÉTODOS
E COMPOSIÇÕES QUIMICAS AGRICOLAS PARA CONTROLE DE PLANTA, MÉTODO DE REDUÇÃO DE EXPRESSÃO DE UM GENE ACCase EM UMA PLANTA, CASSETE DE EXPRESSÃO MICROBI- ANA, MÉTODO PARA FAZER UM POLINUCLEOTÍDEO, MÉTODO DE IDENTIFICAÇÃO DE POLINUCLEOTÍDEOS ÚTEIS NA MODU- LAÇÃO DE EXPRESSÃO DO GENE ACCase E COMPOSIÇÃO HERBICIDA".
[001] Este pedido reivindica o benefício sob 35USC & 119(e) do pedido provisório dos Estados Unidos número de série 61/534.073 de- positado em 13/09/2011, incorporado neste documento por referência, em sua totalidade. A listagem de sequência que está contida no arqui- vo denominado "40 21(58637) B seg listing.ixt", que é 2.094.591 bytes (medidos no sistema operacional MS-Windows) e foi criada em 6 de setembro de 2012, é depositada e incorporada aqui por referência.
CAMPO DA INVENÇÃO
[002] A invenção refere-se geralmente ao campo de manejo de ervas daninhas. Mais especificamente, a invenção refere-se aos genes de acetil-CoA carboxilase (ACCase) em plantas com ervas daninhas e composições contendo moléculas de polinucleotídeos para modular sua expressão. A invenção adicionalmente provê métodos e composi- ções úteis para controle de ervas daninhas.
ANTECEDENTES DA INVENÇÃO
[003] Ervas daninhas são plantas que competem com plantas cultivadas em um ambiente agronômico e custam aos agricultores bi- lhões de dólares anualmente em perdas de safra e a despesa de es- forços para manter as ervas daninhas sob controle. Ervas daninhas também servem como hospedeiros para doenças e pragas de safras. Prejuízos causados pelas ervas daninhas em ambientes de produção agrícola incluem diminuições do rendimento da safra, redução da qua-
1a/531 lidade da safra, custos de irrigação elevados, custos de colheita eleva- dos, valor de terra reduzido, lesão ao gado e danos de safra causados por insetos e doenças alojados pelas ervas daninhas.
O meio principal pelo qual as ervas daninhas causam esses efeitos são: 1) competir com as plantas de cultivo por água, nutrientes, luz solar e outros itens essenciais para o crescimento e desenvolvimento, 2) produção de tó-
xicos ou químicos irritantes que causam problemas de saúde humana ou animal, 3) produção de imensas quantidades de sementes ou par- tes de reprodução vegetativas ou ambos que contaminam produtos agrícolas e perpetuam as espécies em terras agrícolas e 4) produção em terras agrícolas e não agrícolas de grandes quantidades de vege- tação que deve ser descartada. Ervas daninhas tolerantes a herbicidas são um problema com quase todos os herbicidas em uso, há uma ne- cessidade de gestão eficaz destas ervas daninhas. Existem mais de 365 biótipos de ervas daninhas atualmente identificados como sendo resistentes a herbicidas a um ou mais herbicidas, o Comitê de Ação de Resistência a Herbicida (HRAC), o Comitê de Ação de Resistência a Herbicida Norte Americano (NAHRAC) e A Sociedade de Ciência de Ervas Daninhas da América (WSSA).
[004] Enzima de acetil-CoA carboxilase (ACCase) catalisa a car- boxilação dependente de biotina de acetil-CoA para produzir malonil- CoA, esta é a primeira e a etapa empenhada na biossíntese de ácidos graxos de cadeia longa. Esta enzima é o alvo de muitos herbicidas que incluem membros das famílias químicas de ariloxifenoxipropionatos, ciclo-hexanodionas e fenilpirazolina.
SUMÁRIO DA INVENÇÃO
[005] Em um aspecto, a invenção provê um método de controle de planta com ervas daninhas compreendendo uma aplicação externa a uma planta com ervas daninhas de uma composição compreenden- do um polinucleotídeo e um agente de transferência, em que o polinu- cleotídeo é essencialmente idêntico ou essencialmente complementar a uma sequência do gene ACCase ou fragmento da mesma, ou ao transcript de RNA da referida sequência do gene ACCase ou fragmen- to da mesma, em que a referida sequência do gene ACCase é sele- cionada do grupo constituído pela SEQ ID nº: 1-92 ou um fragmento de polinucleotídeo da mesma, por meio do que a capacidade de cres-
cimento ou de desenvolvimento ou reprodutora da planta com ervas daninhas é reduzida ou a planta com ervas daninhas é tornada mais sensível a um herbicida inibidor de ACCase em relação a uma planta com ervas daninhas não tratada com referida composição. Desta for- ma, plantas que se tornaram resistentes à aplicação de herbicidas contendo inibidor de ACCase podem ser tornadas mais suscetíveis aos efeitos herbicidas de um herbicida contendo inibidor de ACCase, potencializando assim o efeito do herbicida. O fragmento de polinucle- otídeo é pelo menos 18 nucleotídeos contíguos, pelo menos 19 nucle- otídeos contíguos, pelo menos 20 nucleotídeos contíguos ou pelo me- nos 21 nucleotídeos contíguos em comprimento e pelo menos 85 por cento idênticos a uma sequência do gene ACCase selecionada do grupo constituído pela SEQ ID nº: 1-92 e o agente de transferência é uma composição ou composto de organossilicone. O fragmento de po- linucleotídeo pode também ser ssDNA ou ssRNA, dsRNA, ou dsDNA ou híbridos de dsDNA/RNA senso ou anti-senso. A composição pode incluir mais de um fragmento de polinucleotídeo, e a composição pode incluir um herbicida inibidor de ACCase e/ou outros herbicidas que aumentam a atividade de controle de ervas daninhas da composição.
[006] Em outro aspecto da invenção, moléculas de polinucleotí- deos e métodos para modular a expressão de gene ACCase em espé- cies de plantas com ervas daninhas são providos. O método reduz, reprime ou de outro modo retarda a expressão de um gene ACCase em uma planta com ervas daninhas compreendendo uma aplicação externa a uma planta com ervas daninhas de uma composição com- preendendo um polinucleotídeo e um agente de transferência, em que o polinucleotídeo é essencialmente idêntico ou essencialmente com- plementar a uma sequência do gene ACCase, reprime ou de outro modo retarda, ou ao transcript de RNA da sequência do gene ACCase, reprime ou de outro modo retarda, em que a sequência do gene AC-
Case é selecionada do grupo constituído pela SEQ ID nº: 1-92 ou um fragmento de polinucleotídeo da mesma. O fragmento de fragmento de polinucleotídeo é pelo menos 18 nucleotídeos contíguos, pelo menos 19 nucleotídeos contíguos, pelo menos 20 nucleotídeos contíguos ou pelo menos 21 nucleotídeos contíguos em comprimento e pelo menos 85 por cento idêntico a uma sequência do gene ACCase selecionada do grupo constituído pela SEQ ID nº: 1-92 e o agente de transferência é um composto de organossilicone. O fragmento de polinucleotídeo pode também ser ssDNA ou ssRNA, dsRNA, ou dsDNA ou híbridos de dsDNA/RNA senso ou anti-senso.
[007] Em um aspecto adicional da invenção, a molécula de poli- nucleotídeo contendo composição da invenção pode ser combinada com outros compostos herbicidas para prover controle adicional de plantas indesejadas em um campo de plantas cultivadas.
[008] Em um aspecto adicional, a composição da molécula de polinucleotídeo pode ser combinada com qualquer um ou mais quími- cos agrícolas adicionais, tais como, inseticidas, fungicidas, nematoci- das, bactericidas, acaricidas, reguladores de crescimento, químio este- rilizantes, semio químicos, repelentes, atrativos, feromônios, estimu- lantes de alimentação, biopesticidas, pesticidas microbianos ou outros compostos biologicamente ativos para formar um pesticida de múlti- plos componentes dando um espectro ainda mais amplo de proteção agrícola.
BREVE DESCRIÇÃO DAS FIGURAS
[009] As figuras seguintes fazem parte do presente relatório des- critivo e estão incluídas para demonstrar adicionalmente certos aspec- tos da presente invenção. A invenção pode ser melhor entendida por referência a uma ou mais dessas figuras em combinação com a des- crição detalhada de modalidades específicas aqui apresentadas. A in- venção pode ser mais plenamente entendida a partir da seguinte des-
crição das figuras:
[0010] Figura 1. Tratamento de Amaranthus palmeri com polinu- cleotídeos desencadeadores de ssDNA e herbicida inibidor de ACCa- se, cletodim.
DESCRIÇÃO DETALHADA
[0011] São providos métodos e composições contendo um polinu- cleotídeo que provê a regulação, repressão ou retardo da expressão do gene ACCase (Acetyl-CoA carboxilase) e controle aprimorado de espécies de planta com ervas daninhas e biótipos de ervas daninhas resistentes de forma importante ao inibidor de ACCase. Aspectos do método podem ser aplicados para gerenciar várias plantas com ervas daninhas em ambientes agrônomos e outros cultivados.
[0012] As seguintes definições e métodos são providos para definir melhor a presente invenção e guiar aqueles versados ordinariamente na técnica na prática da presente invenção. A menos que indicado em contrário, os termos devem ser entendidos de acordo com o uso con- vencional por aqueles versados ordinariamente na técnica relevante. Onde um termo é provido no singular, os inventores também contem- plam aspectos da invenção descritos pelo plural daquele termo.
[0013] Por polinucleotídeos "não possíveis de transcrever" signifi- ca-se que os polinucleotídeos não compreendem uma unidade de transcrição completa de polimerase Il. Como utilizado aqui "solução" refere-se a misturas homogêneas e não homogêneas tais como sus- pensões, colóides, micelas e emulsões.
[0014] Plantas com ervas daninhas são plantas que competem com as plantas cultivadas, aquelas de particular importância incluem, mas não estão limitadas às importantes ervas daninhas nocivas e in- vasoras e biótipos resistentes ao herbicida da produção de safra, tais como, Amaranthus espécies -A. albus, A. blitoides, A. hybridus, A. palmeri, A. powellii, A. retroflexus, A. spinosus, A. tuberculatus, e
A.viridis; Ambrosia species - A. trifida, A. artemisifolia; Lolium species - L. multiflorum, L. rigidium, L perenne; Digitaria species -D. insularis; Euphorbia species -E. heterophylla; Kochia species - K. scoparia; Sor- ghum species -S. halepense; Conyzaspecies -C. bonariensis, C. cana- densis, C. sumatrensis; Chloris species -C. truncate; Echinochola spe- cies - E. colona, E.crus-galli; Eleusine species -E. indica; Poa species - P. annua; Plantago species -P. lanceolata; Avena species - A. fatu- a;Chenopodium species - C. album; Setaria species — S. viridis, Abuti- lon theophrasti, Ipomoea species, Sesbania,species, Cassia species, Sida species, Brachiaria, species e Solanum species.
[0015] Espécies de plantas com ervas daninhas encontradas em áreas cultivadas incluemAlopecurus Alopecurus, Avena sterilis, Avena sterilis ludoviciana, Brachiariaplantaginea, Bromus diandrus, Bromus rigidus, Cynosurus echinatus, Digitaria ciliaris, Digitaria ischaemum, Digitaria sanguinalis, Echinochloa oryzicola, Echinochloa phyllopogon, Eriochloa punctata, Hordeum glaucum, Hordeum leporinum, Ischae- mum rugosum, Leptochloa chinensis, Lolium persicum, ,Phalaris mi- nor, Phalaris paradoxa, Rottboellia exalta, Setaria faberi, Setaria viridis var, robusta-alba schreiber, Setaria viridis var, robusta - bpurpurea, Snowdenia polystachea, Sorghum sudanese, Alisma planta- go-aquatica, Amaranthus lividus, Amaranthus quitensis, Ammania au- riculata, Ammaniacoccinea, Anthemis cotula, Apera spica-venti, Baco- pa rotundifolia, Bidens pilosa, Bidens subalternans, Brassica tournefor- ti, Bromus tectorum, Camelinamicrocarpa, Chrysanthemum coronari- um, Cuscuta campestris, Cyperus difformis, Damasonium minus, Des- curainia sophia, Diplotaxis tenuifolia, Echiumplantagineum, Elatine tri- andra var, pedicellata, Euphorbia heterophylla, Fallopia convolvulus, Fimbristylis miliacea, Galeopsis tetrahit, Galium spurium,Helianthus annuus, Iva xanthifolia, IXophorus unisetus, Ipomoea indica, Ipomoea purpurea, Ipomoea sepiaria, Ipomoea aquatic, Ipomoea triloba, Lactu-
caserriola, Limnocharis flava, Limnophila erecta, Limnophila sessiliflo- ra, Lindernia dubia, Lindernia dubia var, major, Lindernia micrantha, Linderniaprocumbens, Mesembryanthemum crystallinum, Monochoria korsakowii, Monochoria vaginalis, Neslia paniculata, Papaver rhoeas, Partheniumhysterophorus, Pentzia suffruticosa, Phalaris minor, Ra- bphanus raphanistrum, Raphanus sativus, Rapistrum rugosum, Rotala indica var, uliginosa,Sagittaria quyanensis, Sagittaria montevidensis, Sagittaria pygmaea, Salsola iberica, Scirpus juncoides var, ohwianus, Scirpus mucronatus, Setarialutescens, Sida spinosa, Sinapis arvensis, Sisymbrium orientale, Sisymbrium thellungii, Solanum ptycanthum, Sonchus asper, Sonchus oleraceus, Sorghum bicolor, Stellaria media, Thlaspi arvense, Xanthium strumarium, Arctotheca calendula, Conyza sumatrensis, Crassocephalum crepidiodes, Cuphea carthagenenis, Epi- lobium adenocaulon, Erigeron philadelphicus, Landoltia punctata, Le- pidium virginicum, Monochoria korsakowii, Solanumamericanum, Sola- num nigrum, Vulpia bromoides, Youngia japonica, Hydrilla verticillata, Carduus nutans, Carduus pycnocephalus, Centaurea solstitia- lis, Cirsium arvense, Commelina diffusa, Convolvulus arvensis, Daucus carota, Digitaria ischaemum, Echinochloa crus-pavonis, Fimbristylis miliacea, Galeopsis tetrahit, Galium spurium, Limnophila erecta, Matri- caria perforate, Papaver rhoeas, Ranunculus acris, Soliva sessilis, S- phenoclea zeylanica, Stellaria media, Nassella trichotoma, Stipa neesi- ana, Agrostis stolonifera, Polygonum aviculare, Alopecurus japonicus, Beckmannia syzigachne, Bromustectorum, Chloris inflate, Echinochloa erecta, Portulaca oleracea, e Senecio vulgaris.. Acredita-se que todas as plantas contêm um gene fitoeno desaturase em seu genoma, cuja sequência pode ser isolada e polinucleotídeos feitos de acordo com os métodos da presente invenção que são úteis para regular, suprimir ou retardar a expressão do gene ACCase alvo nas plantas e o crescimen- to ou desenvolvimento das plantas tratadas.
[0016] Algumas plantas cultivadas podem também ser plantas com ervas daninhas quando elas ocorrem em ambientes indesejados. Por exemplo, plantas de milho crescendo em um campo de soja. Safras transgênicas com tolerâncias a um ou mais herbicidas precisarão de métodos especializados de gestão para controlar ervas daninhas e plantas de safra voluntárias. A presente invenção permite o direciona- mento de um transgene para tolerância a herbicida permitir que as plantas tratadas tornem-se sensíveis ao herbicida. Por exemplo, as sequências de DNA de ACCase em eventos transgênicos que incluem DAS-40278-9.
[0017] Um "desencadeador" ou "polinucleotídeo desencadeador" é uma molécula de polinucleotídeo que é homóloga ou complementar a um polinucleotídeo do gene alvo. As moléculas de polinucleotídeo de- sencadeador modulam a expressão do gene alvo quando aplicadas topicamente a uma superfície de planta com um agente de transferên- cia, pelo qual uma planta tratada com referida composição tem sua capacidade de crescimento ou desenvolvimento ou reprodutora regu- lada, suprimida ou retardada ou referida planta é mais sensível a um herbicida inibidor de ACCase como um resultado da referida composi- ção contendo polinucleotídeo relativa a uma planta não tratada com uma composição contendo a molécula desencadeadora.
[0018] Contempla-se que a composição da presente invenção irá conter vários polinucleotídeos e herbicidas que incluem, mas não limi- tados aos polinucleotídeos desencadeadores do gene ACCase e um herbicida inibidor de ACCase e qualquer um ou mais polinucleotídeos desencadeadores de gene alvo de herbicida adicionais e os herbicidas relacionados e qualquer um ou mais polinucleotídeos desencadeado- res de gene essencial adicionais. Genes essenciais são genes em uma planta que provêm enzimas-chave ou outras proteínas, por e- xemplo, uma enzima biossintética, enzima de metabolização, receptor,
proteína de transdução de sinal, produto do gene estrutural, fator de transcrição ou proteína de transporte; ou RNAs de regulação, tais co- mo, microRNAs, que são essenciais para o crescimento ou sobrevi- vência do organismo ou célula ou envolvidos no crescimento normal e desenvolvimento da planta (Meinke, et al., Trends Plant Sci. 2008 Set;13(9):483-91). A supressão de um gene essencial aumenta o efei- to de um herbicida que afeta a função de um produto de gene diferente do gene essencial suprimido. As composições da presente invenção podem incluir vários polinucleotídeos desencadeadores que modulam a expressão de um gene essencial que não ACCase.
[0019] Herbicidas para os quais transgenes para tolerância de planta foram demonstrados e o método da presente invenção pode ser aplicado, incluem mas não são limitados a: herbicidas tipo auxina, gli- fosato, glufosinato, sulfonilureias, imidazolinonas, bromoxinil, delapon, dicamba, ciclohezanodiona, inibidores de protoporfirionogênio oxidase, herbicidas inibidores de 4-hidroxifenil-piruvato-dioxigenase. Por exem- plo, transgenes e suas moléculas de polinucleotídeos que codificam proteínas envolvidas na tolerância a herbicida são conhecidos na téc- nica e incluemy mas não estão limitados a uma 5- enolpiruvilshiquimato-3-fosfato sintase (EPSPS), por exemplo, como mais totalmente descrito na Pat. US Nos. 7,807,791 (SEQ ID NO:5); 6,248,876 B1; 5,627,061; 5,804,425; 5,633,435; 5,145,783; 4,971,908; 5,3072,910; 5,188,642;4,940,835; 5,866,775; 6,225,114 B1; 6,130,366; 5,3070,667; 4,535,060; 4,769,061; 5,633,448; 5,510,471; Pat. US No. Re. 36,449; Pat. US Nos. RE 37.287 E; e 5.491.288; tolerância a sul- fonilureia e/ou imidazolinona, por exemplo, como descrito mais plena- mente na Pat. US Nos. 5.605.011; 5.013.659; 5.141.870; 5.767.361;
5.7307.180; 5.304.732; 4./61.3/3; 5.3307.107; 5.928.937; e
5.378.824; e publicação internacional WO 96/33270; tolerância aos herbicidas inibidores de hidroxifenilpiruvatodioxigenases em plantas é descrita em Pat.
US Nos. 6,245,968 B1; 6,268,549; e 6,069,115; Pub.
Pat.
US 20110191897 e US7,3072,379 SEQ ID NO: 3; US7, 935,869; US7,304,209, SEQ ID n º: 1, 3,5 e 15; polinucleotídeos de ariloxialca- noato dioxigenase, que confere tolerância ao 2,4-D e outros herbicidas de fenóxi auxina bem como para herbicidas de ariloxifenoxipropionato conforme descrito, por exemplo, em WOZ2005/107437; US7,838,733 SEQ ID NO: 5;) e polinucleotídeos de tolerância de dicamba conforme descrito, por exemplo, em Herman et al. (2005) J.
Biol.
Chem. 280: 24759-24767. Outros exemplos de traços de tolerância a herbicida in- cluem aqueles conferidos pelos polinucleotídeos que codificam uma fosfinotricina acetiltransferase exógena, conforme descrito na Pat.
U.S.
Nos. 5,969,213; 5,489,520; 5,550,3078; 5,874,265; 5,919,675; 5,561,236; 5,648,477; 5,646,024; 6,177,616; e 5,879,903. Plantas con- tendo uma fosfinotricina acetiltransferase exógena podem exibir tole- rância melhorada aos herbicidas de glufosinato, que inibem a enzima glutamina sintase.
Além disso, polinucleotídeos de tolerância a herbi- cida incluem aqueles conferidos por polinucleotídeos que conferem atividade de protoporfirinogênio oxidase (protox) alterada, conforme descrito em Pat.
U.S.
Nos. 6,288,306 B1; 6,282,837 B1; e 5,767,3/3; e WO 01/12825. Plantas que contenham tais polinucleotídeos podem apresentar maior tolerância a qualquer um de uma variedade de herbi- cidas que têm como alvo a enzima protox (também referidos como ini- bidores de protox). Polinucleotídeos codificando um glifosato oxidorre- dutase e um glifosato-N-acetil transferase (GOX descrito na Patente US 5.463.175 e GAT descrito na publicação de Patente US 20030083480, dicamba monooxigenase publicação de Patente US 20030135879, todas das quais são incorporadas aqui por referência); uma molécula de polinucleotídeo codificando bromoxinil nitrilase (Bxn descrita na Patente US No. 4.810.648 para tolerância de bromoxinil, que é incorporada aqui por referência); uma molécula de polinucleotí-
deo codificando desaturase (crtl) descrito em Misawa et al., (1993) Plant J. 4:833-840 e Misawa et al, (1994) Plant J. 6:481-489 para tole- rância de norflurazon; uma molécula de polinucleotídeo codificando sintase de acetohidroxiácido (AHAS, akaALS) descrito em Sathasiivan et al. (1990) Nucl. Acids Res. 18:3078-2193 para tolerância à herbici- das de sulfonilurea ; e o gene bar descrito no DeBlock, et al. (1987) EMBO J. 6:2513-2519 para tolerância de glufosinato e bialafos. As re- giões de codificação transgênicas e elementos regulatórios de genes de tolerância a herbicida são alvos nos quais desencadeadores de po- linucleotídeos e herbicidas podem ser incluídos na composição da presente invenção.
[0020] A composição da presente invenção inclui um componente que é um herbicida inibidor de ACCase, que inclui membros das famílias químicas de ariloxifenoxipropionatos, ciclo-hexanodionas e fenilpirazolina que incluem, mas não estão limitados a um ariloxifeno- xipropionato compreeendendo clodinafop (ácido propanoicom, 2-[4-[(5- cloro-3-fluoro-2-piridinil)óxilfenóxil-, 2-propinil éster, (2R)), cihalofope (butil(2R)-2-[4-(4-ciano-2-fluorofenóxi)fenóxilpropionato), diclofop (metil 2-[4-(2 4-diclorofenoxi)fenóxilpropanoato), fenoxaprop (etil (R)-2-[4-(6- cloro-1,3-benzoxazol-2-iloxi)fenóxilpropionato), ácido fluazifop (2R)-2- [4-[[5-(trifluorometil)-2-piridinilJóxilfenóxilpropanoico), ácido haloxifop (2-[4-[[3-cloro-S5-(triluorometil)-2-piridinilJóxilfenóxilpropanoico), propaquizafop (2-[[(1-metiletilideno)amino]óxiletil (2R)-2-[4-[(6-cloro- 2quinoxalinil)óxilfenóxilpropanoato) e ácido quizalofop(2R)-2-[4-[(6- cloro-2-quinoxalinil)óxilfenóxilpropanoico; um ciclo-hexanediona com- preendendo aloxidim (metil 2,2-dimetil-4,6-dioxo-5-[(1E)-1-[(2-propen- 1-iloxi)imino]butillciclo-hexanocarboxilato), butroxidim (2-[1-(etoxiimi- no)propil]-3-hidróxi-5-[2,4,6-trimetil-3-(1-oxobutil)fenil]-2-ciclo-hexen-1- ona), cletodim (2-[1-[[[(2E)-3-cloro-2-propen-1-ilJóxilimino]propil]-5-[2- (etiltio)propil]-3-hidróxi-2-ciclo-hexen-1-ona), cicloxidim (2-[1-
(etoxiimino)butil]-3-hidróxi-5-(tetra-hidro-2H-tiopiran-3-il)-2-ciclo-hexen- 1-ona) profoxidim (2-[1-[[2-(4-clorofenoxi)propóxilimino]butil]-3-hidróxi- 5-(tetra-hidro-2H-tiopiran-3-il)-2-ciclo-hexen-1-ona), setoxidim (2-[1- (etoxiimino)butil]-5-[2-(etiltio)propil]-3-hidróxi-2-ciclo-hexen-1-ona), tepraloxidim (2-[1-[[[(2E)-3-cloro-2-propen-1-ilJóxilimino]propi!]-3- hidróxi-5-(tetra-hidro-2H-piran-4-i1)-2-ciclo-hexen-1-ona) e tralcoxidim (2-[1-(etoxiimino)propil]-3-hidróxi-5-(2,4,6-trimetilfenil)-2-ciclo-hexen-1- ona); uma fenilpirazolina compreendendo pinoxaden (8-(2,6-dietil-4- metilfeni!|)-1,2,4,5-tetra-hidro-7-0x0-7H-pirazolo[1,2-01[1,4,5]oxadiaze- pin-9-il 2,2-dimetilpropanoato).
[0021] Inúmeros herbicidas com modos similares ou diferentes de ação (aqui referidos como co-herbicidas) estão disponíveis que podem ser adicionados à composição da presente invenção, por exemplo, membros de famílias de herbicida que incluem mas não estão limita- dos a herbicidas de amida, herbicidas de ácido aromático, herbicidas de arsênico, herbicidas de benzotiazol, herbicidas de benzoilciclo- hexanodiona, herbicidas de benzofuranil alquilsulfonato, herbicidas de carbamato, herbicidas de ciclo-hexeno oxima, herbicidas de ciclopropi- lisoxazol, herbicidas de dicarboximida, herbicidas de dinitroanilina, herbicidas de dinitrofenol, herbicidas de difenil éter, herbicidas de diti- ocarbamato, herbicidas de halogenados alifáticos, herbicidas de imi- dazolinona, herbicidas inorgânicos, herbicidas de nitrila, herbicidas de organofósforo, herbicidas de oxadiazolona, herbicidas de oxazol, her- bicidas de fenoxi, herbicidas de fenilenodiamina, herbicidas de pirazol, herbicidas de piridazina, herbicidas de piridazinona, herbicidas de piri- dina, herbicidas de pirimidinadiamina, herbicidas de pirimidiniloxiben- zilamina, herbicidas de amônio quaternário, herbicidas de tiocarbama- to, herbicidas de tiocarbonato, herbicidas de tioureia, herbicidas de tri- azina, herbicidas de triazinona, herbicidas de triazol, herbicidas de tri- azolona, herbicidas de triazolopirimidina, herbicidas de uracil , e herbi-
cidas de ureia.
Em particular, as taxas de uso dos herbicidas adiciona- dos podem ser reduzidas em composições compreendendo os polinu- cleotídeos da invenção.
Reduções de taxa de uso dos herbicidas adi- cionados adicionais podem ser de 10-25 por cento, 26-50 por cento, 51-75 por cento ou mais podem ser alcançadas que aumentam a ativi- dade dos polinucleotídeos e composição de herbicida e são contem- pladas como um aspecto da invenção.
Co herbicidas representantes das famílias incluem mas não estão limitados a acetocloro, acifluorfe- no, acifluorfeno-sódio, aclonifeno, acroleína, alacloor, aloxidim, álcool alílico, ametrino, amicarbazona, amidosulfuron, aminopiralid, amitrol, sulfamato de amônio, anilofos, asulam, atraton, atrazina, azimsulfuron, BCPC, beflubutamida, benazolina, benfluralina, benfuresato, bensulfu- ron, bensulfuron-metil, bensulida, bentazona, benzfendizona, benzobi- ciclon, benzofenap, bifenox, bilanafos, bispiribac, bispiribac-sódio, bó- rax, bromacil, bromobutídeo, bromoxinil, butacloro, butafenacil, butami- fos, butralin, butroxidim, butilato, ácido cacodílico, clorato de cálcio, cafenstrol, carbetamida, carfentrazona, carfentrazona-etil, CDEA, CEPC, clorflurenol, clorflurenol-metil, cloridazon, clorimuron, clorimu- ron-etil, ácido cloroacético, clorotoluron, clorprofam, clorsulfuron, clor- tal, clortal-dimetil, cinidon-etil, cinmetilina, cinosulfuron, cisanilida, cle- todim, clodinafop, clodinafop-propargil, clomazona, clomeprop, clopira- lid, cloransulam, cloransulam-metil, CMA, 4-CPB, CPMF, 4-CPP, CPPC, cresol, cumiluron, cianamida, cianazina, cicloato, ciclosulfamu- ron,cicloxidim, cihalofop, cihalofop-butil, 2,4-D, 3,4-DA, daimuron, da- lapon, dazomet, 2,4-DB, 3,4-DB, 2,4-DEB, desmedifam, dicamba, di- clobenil, orto-diclorobenzeno, para-diclorobenzeno,diclorprop, diclor- prop-P, diclofop, diclofop-metil, diclosulam, difenzoquat, difenzoquat metilsulfato, diflufenican, diflufenzopir, dimefuron, dimepiperato, dime- tacloro, dimetametrin,dimetenamida, dimetenamida-P, dimetipina, áci- do dimetilarsínico, dinitramina, dinoterb, difenamida, diquat, diquat di-
brometo, ditiopir, diuron, DNOC, 3,4-DP, DSMA, EBEP, endotal, EPTC,esprocarb, etalfluralina, etametsulfuron, etametsulfuron-metil, etofumesato, etoxifeno, etoxisulfuron, etobenzanid, fenoxaprop-P, fe- noxaprop-P-etil, fentrazamida, sulfato ferroso, flamprop-M,flazasul- furon, florasulam, fluazifop, fluazifop-butil, fluazifop-P, fluazifop-P-butil, flucarbazona, flucarbazona-sódio, flucetosulfuron, flucloralin, flufena- cet, flufenpir, flufenpir-etil, flumetsulam,flumiclorac, flumiclorac-pentil, flumioxazina, fluometuron, fluoroglicofeno, fluoroglicofeno-etil, flupro- panato, flupirsulfuron, flupirsulfuron-metil-sódio, flurenol, fluridona, fluo- rocloridona, fluoroxipir,flurtamona, flutiacet, flutiacet-metil, fomesafeno, foramsulfuron, fosamina, glufosinato, glufosinate-amônio, glifosato, ha- losulfuron, halosulfuron-metil, haloxifop, haloxifop-P, HC-252,hexazi- nona, imazametabenz, imazametabenz-metil, imazamox, imazapic, imazapir, imazaquin, imazetapir, imazosulfuron, indanofan, iodometa- no, iodosulfuron, iodosulfuron-metil-sódio,ioxinil, isoproturon, isouron, isoxaben, isoxaclortol, isoxaflutol, karbutilato, lactofen, lenacil, linuron, MAA, MAMA, MCPA, MCPA-tioetil, MCPB, mecoprop, mecoprop-P, mefenacet, mefluidido, mesosulfuron, mesosulfuron-metil, mesotriona, metam, metamifop, metamitron, metazaclor, metabenztiazuron, ácido metilarsônico, — metildimron, — metil — isotiocianato, — metobenzu- ron,metolacloro, S-metolacloro, metosulam, metoxuron, metribuzin, metsulfuron, metsulfuron-metil, MK-66, molinato, monolinuron, MSMA, naproanilida, napropamida, naptalam, neburon, nicosulfuron,ácido no- nanoico, norflurazon, ácido oleixo (ácidos graxos), orbencarb, ortosul- famuron, orizalin, oxadiargil, oxadiazon, oxasulfuron, oxaziclomefona, oxifluorfen, paraquat, paraquat dicloreto, pebulato,pendimetalina, pe- noxsulam, pentaclorofenol, pentanocloro, pentoxazona, petoxamid, óleos de petróleo , fenmedifam, fenmedifam-etil, picloram, picolinafen, pinoxaden, piperofos,arsenito de potássio, azida de potássio , pretila- cloro, primisulfuron, primisulfuron-metil, prodiamina, profluazol, profo-
xidim, prometon, prometrin, propacilor, propanil, propaquizafop, propa- zina,profam, propisoclor, propoxicarbazona, propoxicarbazona-sódio, propizamida, prosulfocarb, prosulfuron, piraclonil, piraflufen, piraflufen- etil, pirazolinato, pirazosulfuron, pirazosulfuron-etil, pirazoxifen, piri- benzoxim, piributicarb, piridafol, piridato, piriftalid, piriminobac, pirimi- nobac-metil, pirimisulfan, piritiobac, piritiobac-sódio, quinclorac, quin- merac, quinoclamina,quizalofop, quizalofop-P, rimsulfuron, setoxidim, siduron, simazina, simetrin, SMA, arsenito de sódio, azida de sódio, clorato de sódio, sulcotriona, sulfentrazona, sulfometuron, sulfometu- ron-metil,sulfosato, sulfosulfuron, ácudi sulfúrico, óleos tar, 2,3,6-TBA, TCA, TCA-sódio, tebutiuron, tepraloxidim, terbacil, terbumeton, terbuti- lazina, terbutrin, tenilclor, tiazopir, tifensulfuron, tifensulfuron-metil, tio- bencarb, tiocarbazil, topramezona, tralcoxidim, tri-alato, triasulfuron, triaziflam, tribenuron, tribenuron-metil, tricamba, triclopir, trietazina, tri- floxisulfuron, trifloxisulfuron-sódio, trifluralin, triflusulfuron, triflusulfuron- metil, trihidroxitriazina, tritosulfuron, [3-[2-cloro-4-fluoro-5-(-metil-6- triluorometil-2,4-dioxo-,2,3,4-t-etrahidropirimidin-3-il)fenóxi]-2- piridilóxilácido acético etil ester (CAS RN 353292-3-6), ácido 4-[(4,5- dihidro-3-metóxi-4-metil-5-0x0)-H-,2,4-triazol--ilcarbonil- - sulfamoil]-5- metiltiofeno-3-carboxílico (BAY636), BAY747 (CAS RN 33504-84-2), topramezona (CAS RN 2063-68-8), 4-hidróxi-3-[[2-[(2-metoxieto- xi)metil]-6-(trifluoro-metil)-3-piridi-nilJcarbonil]-biciclo[3.2.Joct-3-en-2- ona (CAS RN 35200-68-5), e 4-hidróxi-3-[[2-(3-metoxipropil)-6- (difluorometil)-3-piridinil|carbon-il]-biciclo[3.2.Joct-3-en-2-0na. — Adicio- nalmente, incluindo compostos hervbicidas de modos indeterminados de ação como descrito em CN101279950A, CN101279951A, DE 10000600A1, DE10116399A1, DE 102004054666A1, DE102005014638A1, DE102005014906A1, DE102007012168A1, DE 102010042866A1, DE 10204951A1, DE 10234875A1, DE10234876A1, DE10256353A1, DE10256354A1, DE10256367A1,
EP1157991A2, EP1238586A1, EP2147919A1, EP2160098A?2, JPO3968012B2, JP2001253874A, JP2002080454A, JP2002138075A, JP2002145707A, JP2002220389A, JP2003064059A, JP2003096059A, JP2004051628A, JP2004107228A, JP2005008583A, JP2005239675A, JP2005314407A, JP2006232824A, JP2006282552A, JP2007153847A, JP2007161701A, JP2007182404A, JP2008074840A, JP2008074841A, JP2008133207A, JP2008133218A, JP2008169121A, JP2009067739A, JP2009114128A, JP2009126792A, JP2009137851A, US20060111241A1, US20090036311A1, US20090054240A1, US20090215628A1, US20100099561A1, US20100152443A1, US20110105329A1, US20110201501A1, WO2001055066A?2, WO2001056975A1, WO2001056979A1, WOZ2001090071A?2, WO2001090080A1, — WO2002002540A1 , —WO2002028182A1, WO2002040473A1, WO2002044173A?2, WO2003000679A?2, WO2003006422A1 ; —WOZ2003013247A1, WOZ2Z003016308A1, WO2003020704A1, WO2003022051A1, WO2003022831A1, WO2003022843A1, WOZ2003029243A?, WOZ2003037085A1, WO2003037878A1, WO2003045878A?, WOZ2003050087A2, WO2003051823A1, WO2003051824A1, WO2003051846A?2, WO2003076409A1, WO2003087067A1, WO2003090539A1, WO2003091217A1, WOZ2003093269A?2, WO2003104206A2, WO2004002947A1, WO2004002981A?2, WOZ2004011429A1, WO2004029060A1, WO2004035545A2, WO2004035563A1, WO2004035564A1, WO2004037787A1, WO2004067518A1, WO2004067527A1, WO2004077950A1, WO2005000824A1, WO2005007627A1, WO2005040152A1, WOZ2005047233A1, WO2005047281A1, WO2005061443A?, WO2005061464A1, WO2005068434A1, WO2005070889A1, WO2005089551A1, WO2005095335A1, WO2006006569A1, WO2006024820A1, WO2006029828A1, WO2006029829A1, WO2006037945A1,
WO2006050803A1, WO2006090792A1, WO2006123088A?2, WO2006125687A1, WO2006125688A1, WO2007003294A1, WO2007026834A1, WOZ2007071900A1, WO2007077201A1, WOZ2007077247A1, WO2007096576A1, WO2007119434A1, WOZ2007134984A1, WO2008009908A1, WO2008029084A1, WO2008059948A1, WO2008071918A1, WO2008074991A1, WO2008084073A1, WO2008100426A?2, WO2008102908A1, WOZ2008152072A?2, WO2008152073A?2, WO2009000757A1, WO2009005297A?2, WO2009035150A?2, WO2009063180A1, WO2009068170A?2, WO2009068171A?2, WO2009086041A1, WO2009090401A?2, WO2009090402A?2, WO?2009115788A1, WO2009116558A1, WO2009152995A1, WO2009158258A1, WO2010012649A1, WO2010012649A1, WO2010026989A1, WOZ2010034153A1, WO2010049270A1, WO2010049369A1, WO2010049405A1, WO2010049414A1, WO2010063422A1, WO2010069802A1, WO2010078906A?2, WO2010078912A1, WOZ2010104217A1, WO2010108611A1, WO?2010112826A3, WOZ2010116122A3, WOZ2010119906A1, WO2010130970A1, WOZ2011003776A2, WO2011035874A1, WO2011065451A1, todos dos quais são incorporados aqui por referência.
[0022] Um campo agronômico em necessidade de controle de planta é tratado pela aplicação da composição da presente invenção diretamente na superfície das plantas crescentes, tal como por um s- pray. Por exemplo, o método é aplicado para controlar ervas daninhas em um campo de plantas de cultivo pulverizando o campo com a com- posição. A composição pode ser provida como uma mistura de tanque, um tratamento sequencial de componentes (geralmente a composição contendo polinucleotídeo seguida pelo herbicida), ou um tratamento simultâneo ou mistura de um ou mais dos componentes da composi- ção a partir de recipientes separados. Tratamento do campo pode o-
correr tantas vezes quanto necessário para prover controle de ervas daninhas e os componentes da composição podem ser ajustados para espécies com ervas daninhas específicas-alvo ou famílias de ervas daninhas através da utilização de polinucleotídeos específicos ou composições polinucleotídicas capazes de visar seletivamente as es- pécies específicas ou família de planta a ser controlada. A composição pode ser aplicada em taxas de utilização eficazes de acordo com o tempo de aplicação ao campo, por exemplo, pré-plantio, no plantio, pós-plantio, pós-colheita. Herbicidas inibidores de ACCase podem ser aplicados a um campo em taxas de 10 a 500 g ai/ha (ingrediente ativo por hectare) ou mais. Os polinucleotídeos da composição podem ser aplicados a taxas de 1 a 30 gramas por acre dependendo do número de moléculas desencadeadoras necessário para o escopo de ervas daninhas no campo.
[0023] Plantas de cultivo em que controle de ervas daninhas é ne- cessário incluem , mas não estão limitadas a, i) milho, soja, algodão, canola, beterraba, alfafa, cana de açúcar, arroz e trigo; ii) plantas ve- getais incluindo, mas não limitadas a, tomate, pimentão, pimenta, me- lão, melancia, pepino, berinjela, couve-flor, brócolis, alface, espinafre, cebola, ervilhas, cenouras, milho doce, repolho chinês, alho-poró, fun- cho, moranga, abóbora (squash ou gourd), rabanete, couve de Bruxe- las, tomatilho, feijão de jardim, feijão seco ou quiabo; iii) plantas culiná- rias, incluindo, mas não limitadas a, manjericão, salsa, café ou chá; ou, iv) plantas de frutos, incluindo mas não limitadas a maçã, pêra, cereja, pêssego, ameixa, damasco, banana, banana da terra, uva de mesa, uva de vinho, citros, abacate, manga ou baga; v) uma árvore crescida para uso ornamental ou comercial, incluindo, mas não limitado a, uma árvore de fruta ou noz; ou vi) uma planta ornamental (p. ex., uma plan- ta ornamental ou arbusto ou grama de relva). Os métodos e as com- posições providos aqui também podem ser aplicados a plantas produ-
zidas por um processo de corte, clonagem, ou enxerto (ou seja, uma planta não cultivada a partir de uma semente) incluem plantas e árvo- res de frutos que incluem, mas não estão limitadas a, cítricos, maçãs, abacates, tomates, berinjelas, pepinos, melões, melancias e uvas, bem como várias plantas ornamentais.
Misturas de Pesticidas
[0024] As composições polinucleotídicas podem também ser utili- zadas como misturas com vários produtos químicos agrícolas e/ou in- seticidas, acaricidas e fungicidas, agentes pesticidas e biopesticidas. Exemplos incluem mas não estão limitados a azinfos-metil, acefato, isoxation, isofenfos, etion, etrimfos, oxidemeton-metil, oxideprofos, quinalfos, clorpirifos, clorpirifos-metil clorfenvinfos, cianofos, dioxaben- zofos, diclorvos, disulfoton, dimetilvinfos, dimetoato, sulprofos, diazi- non, tiometon, tetraclorvinfos, temefos, tebupirimfos, terbufos, nale- de,vamidotion, piraclofos, piridafention, pirimifos-metil, fenitrotion, fen- tion, fentoato, flupirazofos, protiofos, propafos, profenofos, foxima, fo- salona, fosmet, formotion, forato,malation, mecarbam, mesulfenfos, metamidofos, metidation, paration, metil paration, monocrotofos, triclor- fon, EPN, isazofos, isamidofos, cadusafos, diamidafos, diclofenti- on,tionazin, fenamifos, fostiazato, fostietano, fosfocarb, DSP, etopro- fos, alanicarb, aldicarb, isoprocarb, etiofencarb, carbaril, carbosulfano, xililcarb, tiodicarb, pirimicarb, fenobucarb,furatiocarb, propoxur, bendi- ocarb, benfuracarb, metomil, metolcarb, XMC, carbofuran, aldoxicarb, oxamil, acrinatrin, aletrin, esfenvalerato, empentrin, cicloprotrin, cihalo- trin, gama-cihalotrin, lambda-cihalotrin, ciflutrin, beta-ciflutrin, ciperme- trin, alfa-cipermetrin, zeta-cipermetrin, silafluofeno, tetrametrin, teflutrin, deltametrin, tralometrin, bifentrin, fenotrin,fenvalerato, fenpropatrin, fu- rametrin, praletrin, flucitrinato, fluvalinato, flubrocitrinato, permetrin, resmetrin, etofenprox, cartap, tiociclam, bensultap, acetamiprid, imida- cloprid, clotianidin,dinotefuran, tiacloprid, tiametoxam, nitenpiram, clor-
fluazuron, diflubenzuron, teflubenzuron, triflumuron, novaluron, novi- flumuron, bistrifluoron, fluazuron, flucicloxuron, flufenoxu- ron,hexaflumuron, lufenuron, cromafenozídeo, tebufenozídeo, halofe- nozídeo, metoxifenozídeo, diofenolan, ciromazina, piriproxifen, bupro- fezin, metopreno, hidropreno, quinopreno, triazamato,endosulfan, clor- fenson, clorobenzilato, dicofol, bromopropilato, acetoprol, fipronil, eti- prol, piretrin, rotenona, sulfato de nicotina, agente BT (Bacillus Thurin- giensis), spinosad, abamectin,acequinocil, amidoflumet, amitraz, eto- xazol, quinometionat, clofentezina, óxido de fenbutatina, dienocloro, cihexatin, spirodiclofen, spiromesifen, tetradifon, tebufenpirad, binapa- cril, bifenazato,piridaben, pirimidifen, fenazaquin, fenotiocarb, fenpiro- ximato, fluacripirim, fluazinam, flufenzin, hexitiazox, propargita, ben- zomato, complex de polinactinn milbemectin, lufenuron, mecar- bam,metiocarb, mevinfos, halfenprox, azadiractin, diafentiuron, indoxa- carb, benzoato de emamectin, oleato de potássio, oleato de sódio, clorfenapir, tolfenpirad, pimetrozina, fenoxicarb,hidrametilnon, amido de hidroxi propil, piridalil, flufenerim, flubendiamida, flonicamid, meta- flumizol, lepimectin, TPIC, albendazol, oxibendazol, oxfendazol, tricla- mida, fensulfotion,fenbendazol, cloridrato de levamisol, tartrato de mo- rantel , dazomet, metam-sódio, triadimefon, hexaconazol, propicona- zol, ipconazol, procloraz, triflumizol, tebuconazol, epoxicona- zol difenoconazol, flusilazol, triadimenol, ciproconazol, metconazol, flu- quinconazol, bitertanol, tetraconazol, triticonazol, flutriafol, penconazol, diniconazol, fenbuconazol, bromuconazol,imibenconazol, simeconazol, miclobutanil, himexazol, imazalil, furametpir, tifluzamida, etridiazol, ox- poconazol, fumarato de oxpoconazol, pefurazoato, protioconazol, piri- fenox, fenarimol,nuarimol, bupirimato, mepanipirim, ciprodinil, pirime- tanil, metalaxil, mefenoxam, oxadixil, benalaxil, tiofanato, tiofanato- metil, benomil, carbendazim, fuberidazol, tiabendazol, man- zeb, propineb, zineb, metiram, maneb, ziram, tiuram, clorotalonil, eta-
boxam, oxicarboxin, carboxin, flutolanil, siltiofam, mepronil, dimetomor- fo, fenpropidin, fenpropimorfo, spiroxamina, tridemorfo,dodemorfo, flu- morfo, azoxistrobin, cresoxim-metil, metominostrobin, orisastrobin, flu- oxastrobin, trifloxistrobin, dimoxistrobin, piraclostrobin, picoxistrobin, iprodiona, procimidona, vinclozolin,clozolinato, flusulfamida, dazomet, metil isotiocianato, cloropicrin, metasulfocarb, hidroxiisoxazol, hidroxii- soxazol de potássio, eclomezol, D-D, carbam, cloreto de cobre básico, sulto de cobre básico, nonilfenolsulfonato de cobre, cobre de oxina, DBEDC, sulfato de cobre anidroso, pentahidrato de sulfato de cobre, hidróxido cúprico, enxofre inorgânico, enxofre molhável, calda sulfo- cálcica, sulfato de zinco, fentin, carbonato de hidrogênio de sódio, car- bonato de hidrogênio de potássio, hipoclorito de sódio, prata, edifen- fos, tolclofos-metil, fosetil, iprobenfos, dinocap, pirazofos, carpropamid, ftalídeo,triciclazol, piroquilona, diclocimet, fenoxanil, casugamicin, vali- damicin, polioxinas, blasticiden S, oxytetraciclina, mildiomícin, strepto- micin, óleo de colza, óleo de máquina, bentiavalicarbisopropil, iprovali- carb, propamocarb, dietofencarb, fluoroimida, fludioxanil, fenpiclonil, quinoxifen, ácido oxolínico, clorotalonil, captan, folpet, probenazol, aci- benzolar-S-maetil, tiadinil, ciflufenamid fenhexamid, diflumetorim, metra- fenona, picobenzamida, proquinazid, famoxadona, ciazofamid, fenami- dona, zoxamida, boscalid, cimoxanil, ditianon, fluazinam, diclofluani- deo, triforina,.isoprotiolano, ferimzona, diclomezina, tecloftalam, penci- curon, cinometionat, acetato de iminoctadina, iminoctadina albesilato, ambam, policarbamato, tiadiazina, cloroneb, niqueldimetilditiocarbama- to, guazatina, dodecilguanidina-acetato, quintozeno, tolilfluanid, anila- zina, nitrotalisopropil, fenitropan, dimetirimol, bentiazol, proteína harpi- na, flumetover, mandipropamida e pentiopirad.
Polinucleotídeos
[0025] Como usado neste documento, o termo "DNA", "Molécula de DNA", "Molécula de polinucleotídeo de DNA" refere-se a um DNA de filamento único (SSDNA) ou molécula de DNA de filamento duplo (dsDNA) de origem genômica ou sintética, tais como, , um polímero de bases de deoxiribonucleotídeo ou uma molécula de polinucleotídeo do DNA. Como usado aqui, o termo "sequência de DNA", "sequência de nucleotídeo do DNA" ou "sequência de polinucleotídeo de DNA" refe- re-se à sequência de nucleotídeos de uma molécula de DNA. Como usado aqui, o termo "RNA", "molécula de RNA", "molécula de polinu- cleotídeo de RNA" refere-se a um RNA de filamento único (sSsRNA) ou molécula de RNA de filamento duplo (dsRNA) de origem genômica ou sintética, tais como, um polímero de bases de ribonucleotídeo que compreendem as regiões de filamento único ou duplo. Salvo indicação em contrário, as sequências de nucleotídeos no texto desta especifi- cação são dadas, quando lido da esquerda para a direita, na direção 5' para 3'. A nomenclatura utilizada neste documento é aquela exigida pelo título 37 do Código de Regulamentos Federais dos Estados Uni- dos $1.822 e estabelecida nas tabelas no Padrão WIPO ST.25 (1998), Apêndice 2, Tabelas 1 e 3.
[0026] Como usado aqui, "polinucleotídeo" refere-se a uma molé- cula de DNA ou RNA que contém vários nucleotídeos e geralmente se refere aos "oligonucleotídeos" (uma molécula polinucleotídica de nor- malmente 50 nucleotídeos ou menos em comprimento) e polinucleotí- deos de 51 ou mais nucleotídeos. Modalidades dessa invenção inclu- em composições incluindo oligonucleotídeos tendo um comprimento de 18-25 nucleotídeos (18-mers, 19-mers, 20-mers, 21-mers, 22-mers, 23-mers, mers-24 ou 25-mers), por exemplo, oligonucleotídeos SEQ ID NO: 3901-4530 ou fragmentos dos mesmos ou polinucleotídeos de comprimento médio tendo um comprimento de 26 ou mais nucleotí- deos (polinucleotídeos de 26, 27, 28, 29, 30, 307, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, cerca de 65, cerca de 70, cerca de 75, cerca de 80,
cerca de 85, cerca de 90, cerca de 95, cerca de 100, cerca de 110, cerca de 120, cerca de 130, cerca de 140, cerca de 150, cerca de 160, cerca de 170, cerca de 180, cerca de 190, cerca de 200, cerca de 210, cerca de 220, cerca de 230, cerca de 240, cerca de 250, cerca de 260, cerca de 270, cerca de 280, cerca de 290, ou cerca de 300 nucle- otídeos), por exemplo, oligonucleotídeos SEQ ID NO: 93-3900 ou fragmentos dos mesmos ou longos polinucleotídeos tendo um com- primento superior a cerca de 300 nucleotídeos (por exemplo, polinu- cleotídeos de entre cerca de 300 a cerca de 400 nucleotídeos, entre cerca de 400 a cerca de 500 nucleotídeos, entre cerca de 500 a cerca de 600 nucleotídeos, entre cerca de 600 a cerca de 700 nucleotídeos, entre cerca de 700 a cerca de 800 nucleotídeos, entre cerca de 800 a cerca de 900 nucleotídeos, entre cerca de 900 a cerca de 1000 nu- cleotídeos, entre cerca de 300 a cerca de 500 nucleotídeos, entre cer- ca de 300 a cerca de 600 nucleotídeos, entre cerca de 300 a cerca de 700 nucleotídeos, entre cerca de 300 a cerca de 800 nucleotídeos, en- tre cerca de 300 a cerca de 900 nucleotídeos, ou cerca de 1000 nucle- otídeos em comprimento, ou até mesmo superior a cerca de 1000 nu- cleotídeos em comprimento, por exemplo, até o comprimento inteiro de um gene alvo, incluindo porções codificantes ou não-codificantes ou ambas codificante ou não codificante do gene do alvo), por exemplo, polinucleotídeos da Tabela 1 (SEQ ID NO: 1-93), em que os polinucle- otídeos selecionados ou fragmentos dos mesmos homólogos ou com- plementares à SEQ ID NO: 1-93 suprime, reprime ou de outro modo retarda a expressão do gene ACCase alvo.
Um gene alvo compreen- de qualquer molécula polinucleotídica em uma célula de planta ou fragmento da mesma para que a modulação da expressão do gene alvo seja provida pelos métodos e composições da presente invenção.
Onde um polinucleotídeo tem filamento duplo, seu comprimento pode ser descrito de forma semelhante em termos de pares de bases.
Os oligonucleotídeos e polinucleotídeos da presente invenção podem ser feitos que são essencialmente idênticos ou essencialmente comple- mentares aos elementos genéticos adjacentes de um gene, por exem- plo, abrangendo a região de junção de um intron e exon, a região da junção de um promotor e uma região transcrita, a região de junção de um líder 5' e uma sequência codificante, a junção de uma região não traduzida 3' e uma sequência de codificação.
[0027] Composições polinucleotídicas usadas nas várias modali- dades dessa invenção incluem composições incluindo oligonucleotí- deos ou polinucleotídeos ou uma mistura de ambos, incluindo híbridos de RNA ou DNA ou RNA/DNA ou oligonucleotídeos quimicamente modificados ou polinucleotídeos ou uma mistura dos mesmos. Em al- gumas modalidades, o polinucleotídeo pode ser uma combinação de ribonucleotídeos e desoxirribonucleotídeos, por exemplo, polinucleotí- deos sintéticos, consistindo principalmente de ribonucleotídeos, mas com um ou mais desoxirribonucleotídeos terminais ou polinucleotídeos sintéticos consistindo principalmente de desoxirribonucleotídeos, mas com um ou mais didesoxirribonucleotídeos terminais. Em algumas modalidades, o polinucleotídeo inclui nucleotídeos não-canônicos, tais como inosina, tiouridina ou pseudouridina. Em algumas modalidades, o polinucleotídeo inclui nucleotídeos quimicamente modificados. E- xemplos de oligonucleotídeos quimicamente modificados ou polinucle- otídeos são bem conhecidos na técnica; ver, por exemplo, Publicação de Patente US20110171287, Publicação de Patente US20110171176 e Publicação de Patente US20110152353, Publicação de Patente US 20110152346, Publicação de Patente US20110160082, incorporadas aqui por referência. Por exemplo, incluindo mas não limitado à cadeia principal de fosfodiéster de ocorrência natural de um oligonucleotídeo ou polinucleotídeo pode ser parcialmente ou completamente modifica- da com modificações de ligação internucleotídeos de fosforotioato, fos-
foroditioato ou metilfosfonato, bases de nucleosídeos modificadas ou açúcares modificados podem ser usados na síntese de oligonucleotí- deo ou polinucleotídeo e oligonucleotídeos ou polinucleotídeos podem ser rotulados com uma fração fluorescente (por exemplo, fluoresceína ou rodamina) ou outro rótulo (por exemplo, biotina).
[0028] Os polinucleotídeos podem ser RNA de filamento único ou duplo ou DNA de filamento único ou duplo ou híbridos de DNA/RNA de filamento duplo ou análogos modificados dos mesmos, e podem ser de comprimentos oligonucleotídicos ou maiores. Em modalidades mais específicas da invenção, os polinucleotídeos que provêm RNA de fila- mento único na célula de planta são selecionados do grupo constituído de (a) uma molécula de RNA de filamento único (SSRNA), (b) uma mo- lécula de RNA de filamento único que auto hibridiza para formar uma molécula de RNA de filamento duplo, (c) uma molécula de RNA de fi- lamento duplo (dsRNA), (d) uma molécula de DNA de filamento único (SSDNA), (e) uma molécula de DNA de filamento único que auto hibri- diza para formar uma molécula de DNA de filamento duplo, e (f) uma molécula de DNA de filamento único incluindo um gene Pol Ill modifi- cado que é transcrito para uma molécula de RNA, (g) uma molécula de DNA de filamento duplo (dsDNA), (h) uma molécula de DNA de fila- mento duplo incluindo um gene Pol Ill modificado que é transcrito para uma molécula de RNA, (i) uma molécula de RNA/DNA hibridizado de filamento duplo, ou combinações das mesmas. Em algumas modalida- des estes polinucleotídeos incluem nucleotídeos quimicamente modifi- cados ou nucleotídeos não-canônicos. Em algumas modalidades, os oligonucleotídeos podem ser de terminação abrupta ou podem com- preender uma saliência 3' de 1-5 nucleotídeos de pelo menos um ou ambos os filamentos. Outras configurações do oligonucleotídeo são conhecidas no campo e estão contempladas neste documento. Em modalidades do método os polinucleotídeos incluem DNA de filamento duplo formado por hibridização intramolecular, DNA de filamento duplo formado por hibridização intermolecular, RNA de filamento duplo for- mado por hibridização intramolecular ou RNA de filamento duplo for- mado por hibridização intermolecular. Em uma modalidade os polinu- cleotídeos incluem DNA de filamento único ou RNA de filamento único que auto hibridiza para formar uma estrutura de hairpin tendo uma es- trutura pelo menos parcialmente com filamento duplo incluindo pelo menos um segmento que hibridizará para RNA transcrito a partir do gene visado para supressão. Não pretendendo ser vinculado por qual- quer mecanismo, acredita-se que tais polinucleotídeos são ou produzi- rão RNA de filamento único com pelo menos um segmento que hibridi- zará para RNA transcrito a partir do gene visado para supressão. Em certas outras modalidades os polinucleotídeos incluem adicionalmente um promotor, geralmente funcional em uma planta, por exemplo, um promotor de pol Il, um promotor de pol Ill, um promotor de pol IV, um promotor de pol V.
[0029] O termo "gene" refere-se a DNA cromossômico, DNA de plasmídeo, cDNA, DNA de íntron e éxon, polinucleotídeo de DNA arti- ficial ou outro DNA que codifica um peptídeo, polipeptídeo, proteína, ou molécula de transcript de RNA e os elementos genéticos que flan- queiam a sequência de codificação que estão envolvidos na regulação da expressão, tais como, regiões promotoras, regiões líder 5', regiões não traduzidas 3'. Qualquer um dos componentes do gene são alvos potenciais para os oligonucleotídeos e polinucleotídeos da presente invenção.
[0030] As moléculas de polinucleotídeo da presente invenção são projetadas para modular a expressão através da indução de regulação ou supressão de um gene ACCase endógeno em uma planta e são projetadas para ter uma sequência de nucleotídeos essencialmente idêntica ou essencialmente complementar à sequência de nucleotí-
deos de um gene ACCase endógeno de uma planta ou à sequência de RNA transcrita a partir de um gene ACCase endógeno de uma planta, incluindo um transgene em uma planta que provê uma enzima de AC- Case resistente a herbicida, que pode ser sequência codificadora ou sequência não-codificadora.
Moléculas eficazes que modulam a ex- pressão são referidas como "uma molécula desencadeadora, ou poli- nucleotídeo desencadeador". Por "essencialmente idêntico" ou "es- sencialmente complementares" significa-se que os polinucleotídeos desencadeadores (ou pelo menos um filamento de um polinucleotídeo de filamento duplo ou porção do mesmo, ou uma porção de um polinu- cleotídeo de filamento único) são projetados para hibridizar para a se- quência não-codificante do gene endógeno ou ao RNA transcrito (co- nhecido como RNA mensageiro ou um transcript do RNA) a partir do gene endógeno para efeito de regulação ou supressão da expressão do gene endógeno.
Moléculas desencadeadoras são identificadas por "telhagem" dos alvos de gene com sondas parcialmente sobrepostas ou sondas não sobrepostas de polinucleotídeos senso ou antisenso que são essencialmente idênticos ou essencialmente complementares à sequência de nucleotídeos de um gene endógeno.
Várias sequên- cias alvo podem ser alinhadas e regiões de sequência com homologia em comum, de acordo com os métodos da presente invenção, são i- dentificadas como moléculas desencadeadoras potenciais para os múltiplos alvos.
Várias moléculas desencadeadoras de vários compri- mentos, por exemplo 18-25 nucleotídeos, 26-50 nucleotídeos, 51-100 nucleotídeos, 101-200 nucleotídeos, 201-300 nucleotídeos ou mais podem ser submetidos a pool em alguns tratamentos para investigar moléculas polinucleotídicas que cobrem uma porção de uma sequên- cia do gene (por exemplo, uma porção de uma codificação versus uma porção de uma região não-codificante, ou uma porção 5' versus uma 3' de um gene) ou uma sequência do gene inteiro incluindo regiões codi-
ficantes e não-codificantes de um gene alvo. Moléculas polinucleotídi- cas das moléculas desencadeadoras submetidas a pool podem ser divididas em pools menores ou moléculas simples para identificar mo- léculas desencadeadoras que provêm o efeito desejado.
[0031] As moléculas polinucleotídicas de RNA e DNA de gene alvo (Tabela 1, SEQ ID NO: 1-93) são sequenciadas por qualquer número de equipamentos e métodos disponíveis. Algumas das tecnologias de sequenciamento estão disponíveis comercialmente, tais como a plata- forma de sequenciamento-por-hibridação de Affymetrix Inc. (Sunnyva- le, Califórnia) e as plataformas de sequenciamento-por-síntese de 454 Life Sciences (Bradford, Connecticut), Illumina/Solexa (Hayward, Cali- fórnia) e Helicos Biosciences (Cambridge, Massachusetts) e a plata- forma de sequenciamento-por-ligadura da Applied Biosystems (Foster City, Califórnia), conforme descrito abaixo. Além do sequenciamento de molécula simples desempenhado usando sequenciamento-por- síntese de Helicos Biosciences, outras tecnologias de sequenciamento de molécula simples são englobadas pelo método da invenção e inclu- em a tecnologia SMRT. TM. da Pacific Biosciences, a tecnologia lon Torrent.TM,, e sequenciamento de nanoporo sendo desenvolvida, por exemplo, pela Oxford Nanopore Technologies. Um gene alvo ACCase compreendendo DNA ou RNA pode ser isolado usando iniciadores ou sondas essencialmente complementares ou essencialmente homólo- gas à SEQ ID NO: 1-93 ou um fragmento dos mesmos. Um fragmento de gene de reação em cadeia da polimerase (PCR) pode ser produzi- do usando iniciadores essencialmente complementares ou essencial- mente homólogos à SEQ ID NO: 1-93 ou um fragmento dos mesmos que é útil para isolar um gene ACCase de um genoma de planta. SEQ ID NO: 1-93 ou fragmentos da mesma podem ser usados em várias tecnologias de captura de sequência para isolar sequências de gene alvo adicionais, por exemplo, incluindo mas não limitado a Roche Nim-
bleGenO (Madison, WI) e DynabeadsO acoplados a Streptavdina (Life Technologies, Grand Island, NY) e US20110015084, incorporados a- qui por referência na sua totalidade.
[0032] Modalidades de polinucleotídeos de filamento único funcio- nais têm complementaridade de sequência que não precisa ser de 100 por cento, mas que seja pelo menos suficiente para permitir hibridiza- ção para RNA transcrito a partir do gene alvo ou DNA do gene alvo para formar um duplex para permitir um mecanismo de silenciamento do gene. Assim, em modalidades, um fragmento de polinucleotídeo é projetado para ser essencialmente idêntico a, ou essencialmente com- plementar a, uma sequência de 18 ou mais nucleotídeos contíguos ou na sequência de gene ACCase ou RNA mensageiro transcrito a partir do gene alvo. Por "essencialmente idênticos" entende-se ter 100 por- cento de identidade de sequência ou pelo menos cerca de 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 porcento de i- dentidade de sequência quando comparado com a sequência de 18 ou mais nucleotídeos contíguos ou no gene alvo ou no RNA transcrito do gene-alvo; por "essencialmente complementar" entende-se ter 100 porcento de complementaridade de sequência ou pelo menos cerca de 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 por- cento de complementaridade de sequência quando comparado à se- quência de 18 ou mais nucleotídeos contíguos no gene alvo ou no RNA transcrito a partir do gene alvo. Em algumas modalidades dessa invenção, moléculas polinucleotídicas são projetadas para ter 100 por cento de identidade de sequência ou complementaridade a um alelo ou um membro da família de um dado gene alvo (sequência codifica- dora ou não-codificadora de um gene da presente invenção); em ou- tras modalidades as moléculas polinucleotídicas são projetadas para ter 100 por cento de identidade de sequência ou complementaridade a alelos múltiplos ou membros da família de um dado gene alvo.
[0033] Em certas modalidades, os polinucleotídeos usados nas composições que são essencialmente idênticos ou essencialmente complementares ao gene alvo ou transcript compreenderão o ácido nucleico predominante na composição. Assim, em certas modalidades, os polinucleotídeos que são essencialmente idênticos ou essencial- mente complementares ao gene alvo ou transcript compreenderão pe- lo menos cerca de 50%, 75%, 95%, 98% ou 100% dos ácidos nuclei- cos providos na composição em concentração molar ou de massa. No entanto, em certas modalidades, os polinucleotídeos que são essenci- almente idênticos ou essencialmente complementares ao gene alvo ou transcript podem compreender pelo menos cerca de 1% a cerca de 50%, cerca de 10% a cerca de 50%, cerca de 20% a cerca de 50%, ou cerca de 30% a cerca de 50% dos ácidos nucleicos providos na com- posição por concentração molar ou de massa. Também são providas composições onde os polinucleotídeos que são essencialmente idênti- cos ou essencialmente complementares ao gene alvo ou transcript po- dem abranger pelo menos cerca de 1% a 100%, cerca de 10% a 100%, cerca de 20% a cerca de 100%, cerca de 30% a cerca de 50%, ou cerca de 50% a 100% dos ácidos nucleicos providos na composi- ção por concentração molar ou de massa.
[0034] "Identidade" refere-se ao grau de similaridade entre duas sequências de ácido polinucleico ou de proteína. Um alinhamento de duas sequências é realizado por um programa de computador ade- quado. Um programa de computador amplamente utilizado e aceito para o desempenho de alinhamentos de sequência é CLUSTALW v
1.6 (Thompson, et al. Nucl. Acids Res., 22: 4673-4680, 1994). O nú- mero de bases correspondentes ou aminoácidos é dividido pelo núme- ro total de bases ou aminoácidos e multiplicado por 100 para obter uma identidade percentual. Por exemplo, se duas sequências com 580 pares de bases tiveram 145 bases combinadas, elas seriam 25 por cento idênticas. Se as duas sequências comparadas são de compri- mentos diferentes, o número de correspondências é dividido pelo mais curto dos dois comprimentos. Por exemplo, se houver 100 aminoáci- dos combinados entre uma proteína com 200 e uma com 400 aminoá- cidos, eles são 50 por cento idênticos no que diz respeito à sequência mais curta. Se a sequência mais curta tiver menos de 150 bases ou 50 aminoácidos em comprimento, o número de combinações é dividido por 150 (para bases de ácidos nucleicos) ou 50 (para aminoácidos) e multiplicado por 100 para obter uma identidade percentual.
[0035] Moléculas desencadeadoras para membros da família de gene específico podem ser identificadas a partir de sequências codifi- cantes e/ou não-codificantes de famílias de gene de uma planta ou múltiplas plantas, alinhando e selecionando 200-300 fragmentos poli- nucleotídicos a partir das regiões menos homólogas entre as sequên- cias alinhadas e avaliadas usando polinucleotídeos topicamente apli- cados (como ssSDNA ou ssRNA senso ou anti-senso, dsRNA, ou dsD- NA) para determinar sua eficácia relativa na indução do fenótipo herbi- cida. Os segmentos eficazes são ainda subdivididos em 50-60 frag- mentos polinucleotídicos, priorizados por pelo menos homologia, e re- avaliados utilizando polinucleotídeos topicamente aplicados. Os 50-60 fragmentos polinucleotídicos eficazes são subdivididos em 19-30 fragmentos polinucleotídicos, priorizados pelo menos por homologia e novamente avaliados para indução do fenótipo de rendimen- to/qualidade. Uma vez que a eficácia relativa é determinada, os frag- mentos são utilizados isoladamente, ou novamente avaliados em combinação com um ou mais outros fragmentos para determinar a composição desencadeadora ou mistura de polinucleotídeos desenca- deadores para prover o fenótipo de rendimento/qualidade.
[0036] Moléculas desencadeadoras para atividade ampla podem ser identificadas a partir de sequências codificadoras e/ou não-
codificadoras de famílias de gene de uma planta ou várias plantas, ali- nhando e selecionando 200-300 fragmentos polinucleotídicos das re- giões mais homólogas entre as sequências alinhadas e avaliadas u- sando polinucleotídeos topicamente aplicados (como ssSDNA ou ssR- NA senso ou anti-senso, dsRNA, ou dsDNA) para determinar sua efi- cácia relativa na indução do fenótipo de rendimento/qualidade. Os segmentos eficazes são subdivididos em 50-60 fragmentos polinucleo- tídicos, priorizados por máxima homologia, e reavaliados usando poli- nucleotídeos topicamente aplicados. Os 50-60 fragmentos polinucleo- tídicos eficazes são subdivididos em 19-30 fragmentos polinucleotídi- cos, priorizados por mais homologia e novamente avaliados para a in- dução do fenótipo de rendimento/qualidade. Uma vez que a eficácia relativa é determinada, os fragmentos podem ser utilizados isolada- mente, ou em combinação com um ou mais outros fragmentos para determinar a composição desencadeadora ou mistura de polinucleotí- deos desencadeadores para prover o fenótipo de rendimento/quali- dade.
[0037] Métodos de fazer polinucleotídeos são bem conhecidos na técnica. Síntese química, síntese in vivo e métodos de síntese in vitro e composições são conhecidos na técnica e incluem vários elementos virais, células microbianas, polimerases modificadas e nucleotídeos modificados. Preparação comercial dos oligonucleotpideos frequente- mente provê dois deoxiribonucleotídeos na extremidade 3' do filamento senso. Moléculas de polinucleotídesos longas podem ser sintetizadas a partir de kits disponíveis comercialmente, por exemplo, kits de da Applied Biosystems/Ambion (Austin, TX) têm DNA ligado na extremi- dade 5' em um cassete de expressão microbiana que inclui um promo- tor de T7 polimerase bacteriano que faz RNA filamentar que pode ser montado em um dsRNA e kits providos por vários fabricantes que in- cluem T7 RiboMax Express (PromegaMadison, WI), AmpliScribe T7-
Flash (Promega Madison, WI) e TranscriptAid T7 High Yeld (Fermen- tas, Glen Burnie, MD). Moléculas de dsRNA podem ser produzidas a partir de cassetes de expressão microbiana em células bacterianas (Ongvarrasopone et al. ScienceAsia 33:35-39; Yin, Appl. Microbiol. Bi- otechnol 84:323-333, 2009; Liu et al, BMC Biotechnology 10:85, 2010) que têm atividade de enzima RNase Ill regulada ou deficiente ou o uso de vários vetores virais para produzir quantidades suficientes de dsR- NA. Na presente invenção, fragmentos de gene ACCase são inseridos nos cassetes de expressão microbiana em uma posição em que os fragmentos são expressos para produzir sSRNA ou dsRNA úteis nos métodos descritos neste documento para regular a expressão de um gene ACCase alvo. Em algumas modalidades, parâmetros de projeto, tais como classificação de Reynolds (Reynolds et al. Nature Biotech- nology 22, 326 - 330 (2004), Tuschl rules (Pei and Tuschl, Nature Me- thods 3(9): 670-676, 2006), i-score (Nucleic Acids Res 35: e123, 2007), ferramenta de i-Score Designer e algoritmos associados (Nucleic Acids Res 32: 936-948, 2004. Biochem Biophys Res Commun 316: 1050- 1058, 2004, Nucleic Acids Res 32: 893-901, 2004, Cell Cycle 3: 790-5, 2004, Nat Biotechnol 23: 995-1001, 2005, Nucleic Acids Res 35: e27, 2007, BMC Bioinformatics 7: 520, 2006, Nucleic Acids Res 35: e123, 2007, Nat Biotechnol 22: 326-330, 2004) são conhecidos na técnica e podem ser utilizados na seleção de sequências polinucleotídicas efica- zes no silenciamento de genes. Em algumas modalidades a sequência de um polinucleotídeo é triada contra o DNA genômico da planta des- tinada para minimizar silenciamento não intencional de outros genes.
[0038] As composições de polinucleotídeo de molécula de polinu- cleotídeo e oligonucleotídeo desencadeadoras são úteis nas composi- ções, tais como líquidos que compreendem essas moléculas polinu- cleotídicas, em baixas concentrações, sozinhas ou em combinação com outros componentes, por exemplo uma ou mais moléculas de herbicidas ou em líquidos aplicados separadamente que também pro- vêm um agente de transferência. Embora não haja nenhum limite su- perior nas concentrações e dosagens de moléculas polinucleotídicas que podem ser úteis nos métodos dessa invenção, doses e concentra- ções eficazes inferiores geralmente serão buscadas para a eficiência. As concentrações podem ser ajustadas tendo em consideração o vo- lume de pulverização ou tratamento aplicado às folhas de plantas ou outras superfícies de parte de plantas, tais como pétalas de flores, caules, tubérculos, frutas, anteras, pólen ou semente. Em uma modali- dade, um tratamento útil para plantas herbáceas usando moléculas de oligonucleotídeo de 25-mer é cerca de 1 nanomol (nmol) de moléculas do oligonucleotídeo por planta, por exemplo, de cerca de 0,05 a 1 nmol por planta. Outras modalidades para plantas herbáceas incluem faixas úteis de cerca de 0,05 a cerca de 100 nmol, ou cerca de 0,1 a cerca de nmol, ou cerca de 1 nmol a cerca de 10 nmol de polinucleotídeos por planta. Plantas muito grandes, árvores ou videiras podem exigir quantidades correspondentemente maiores de polinucleotídeos. Ao usar moléculas de dsRNA longas que podem ser processadas em múl- tiplos oligonucleotídeos, concentrações menores podem ser usadas. Para ilustrar modalidades da invenção, o fator 1X, quando aplicado às moléculas de oligonucleotídeo, é arbitrariamente usado para denotar um tratamento de 0,8 nmol de molécula polinucleotídica por planta; 10X, 8 nmol de molécula polinucleotídica por planta; e 100X, 80 nmol de molécula polinucleotídica por planta.
[0039] As composições de polinucleotídeo dessa invenção são ú- teis nas composições, tais como líquidos que compreendem moléculas polinucleotídicas, sozinhas ou em combinação com outros componen- tes ou no mesmo líquido ou em líquidos separadamente aplicados que provêm agente de transferência. Como usado neste documento, um agente de transferência é um agente que, quando combinado com um polinucleotídeo em uma composição que é aplicada topicamente a uma superfície de planta alvo, permite o polinucleotídeo inserir uma célula de planta.
Em certas modalidades, um agente de transferência é um agente que condiciona a superfície do tecido da planta, p. ex., fo- lhas, caules, raízes, flores ou frutos, à permeação pelas moléculas po- linucleotídicas em células de plantas.
A transferência de polinucleotí- deos em células da planta pode ser facilitada pela aplicação anterior ou contemporânea de um agente de transferência de polinucleotídeo para o tecido da planta.
Em algumas modalidades o agente de transfe- rência é aplicado após a aplicação da composição polinucleotídica.
O agente de transferência de polinucleotídeo permite uma via para poli- nucleotídeos através de barreiras de cera de cutícula, estômatos e/ou parede celular ou barreiras de membrana em células de plantas.
Agen- tes de transferência adequados para facilitar transferência do polinu- cleotídeo em uma célula de planta incluem agentes que aumentam a permeabilidade do exterior da planta ou que aumentam a permeabili- dade das células da planta a oligonucleotídeos ou polinucleotídeos.
Tais agentes para facilitar a transferência da composição em uma cé- lula de planta incluem um agente químico, ou um agente físico ou combinações dos mesmos.
Agentes químicos para condicionamento ou transferência incluem (a) tensoativos, (b) um solvente orgânico ou uma solução aquosa ou misturas aquosas de solventes orgânicos, (c) agentes oxidantes, (d) ácidos, (e) bases, (f) óleos, (g) enzimas ou combinações dos mesmos.
Modalidades do método podem opcional- mente incluir uma etapa de incubação, uma etapa de neutralização (por exemplo, para neutralizar um agente ácido, básico ou oxidante ou para inativar uma enzima), uma etapa de enxágue ou combinações das mesmas.
Modalidades de agentes ou tratamentos para o condi- cionamento de uma planta à permeação por polinucleotídeos incluem emulsões, emulsões reversas, lipossomas e outras composições do tipo micelar. Modalidades de agentes ou tratamentos para o condicio- namento de uma planta à permeação por polinucleotídeos incluem contra-íons ou outras moléculas que são conhecidas por se associa- rem com moléculas de ácido nucleico, por ex., íons de amônio inorgâà- nicos, íons de alquilamônio, íons de lítio, poliaminas, tais como esper- mina, espermidina, ou putrescina e outros cátions. Solventes orgâni- cos úteis no condicionamento de uma planta à permeação por polinu- cleotídeos incluem DMSO, DMF, piridina N-pirrolidina, hexametilfosfo- ramida, acetonitrila, dioxano, polipropileno glicol, outros solventes mis- cíveis com a água ou que irá dissolver fosfonucleotídeos em sistemas não aquosos (tal como é usado em reações sintéticas). Óleos natural- mente derivados ou sintéticos com ou sem tensoativos ou emulsionan- tes podem ser usados, por ex., óleos de origem vegetal, óleos de culti- vo (tais como aqueles listados no 9º Compêndio de Adjuvantes Herbi- cidas, publicamente disponível na worldwide web (internet) em herbici- de.adjuvants.com, podem ser usados, por ex., óleos parafínicos, éste- res de ácido graxo de poliol, ou óleos com moléculas de cadeia curta modificados com amidas ou poliaminas tais como polietilenoimina ou N-pirrolidina. Agentes de transferência incluem, mas não estão limita- dos a, preparações de organossilicone.
[0040] Em certas modalidades, uma preparação de organossilico- ne que é comercialmente disponível como tensoativo Silwet& L-77, tendo número de CAS 27306-78-1 e o número do EPA: CAL.REG.NO. 5905-50073-AA, e atualmente disponível de Momentive Performance Materials, Albany, Nova lorque, pode ser usada para preparar uma composição polinucleotídica. Em certas modalidades onde uma prepa- ração de organossilicone Silwet L-77 é usada como um tratamento pré-pulverização de folhas de plantas ou outras superfícies da planta, concentrações recém feitas na faixa de cerca de 0.015 a cerca de 2 por cento em peso (porcentual em peso) (e. g., cerca de 0.01, 0.015,
0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05, 0.055, 0.06, 0.065, 0.07,
0.075, 0.08, 0.085, 0.09, 0.095, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9,
1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.5% em peso) são eficazes na preparação de uma folha ou outra superfície de planta para transferência de moléculas polinucleotídicas em células vegetais a partir de uma aplicação tópica na superfície. Em determina- das modalidades de métodos e composições providos aqui, uma com- posição que compreende uma molécula polinucleotídica e uma prepa- ração de organossilicone compreendendo Silwet L-77 na faixa de cer- ca de 0.015 a cerca de 2% em peso (porcentual em peso) (e. g., 0.01,
0.015, 0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05, 0.055, 0.06, 0.065,
0.07, 0.075, 0.08, 0.085, 0.09, 0.095, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7,
0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3,
2.5% em peso) são utilizadas ou providas.
[0041] Em certas modalidades, qualquer uma das preparações de organossilicone disponíveis comercialmente providas como a seguir Breakthru S 321, Breakthru S 200 Catit 67674-67-3, Breakthru OE 441 Cattt68937-55-3, Breakthru S 278 Cat t127306-78-1, Breakthru S 243, Breakthru S 233 Catft134180-76-0, disponível do fabriacante Evonik Goldschmidt (Alemanha), Silwet& HS 429, Silwet& HS 312, SilwetO& HS 508, Silwet& HS 604 (Momentive Performance Materials, Albany, Nova lorque) podem ser usados como agentes de transferência em uma composição polinucleotídica. Em certas modalidades onde uma preparação de organossilicone é usada como um tratamento de pré- pulverização de folhas de plantas ou outras superfícies, concentrações recém feitas na faixa de cerca de 0.015 a cerca de 2 por cento em pe- so (% em peso) (p. ex., cerca de 0.01, 0.015, 0.02, 0.025, 0.03, 0.035,
0.04, 0.045, 0.05, 0.055, 0.06, 0.065, 0.07, 0.075, 0.08, 0.085, 0.09,
0.095, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4,
1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.5% em peso) são eficazes na preparação de uma folha ou outra superfície de planta para transfe- rência de moléculas polinucleotídicas em células vegetais a partir de aplicação tópica na superfície. Em certas modalidades dos métodos e composições providos aqui, uma composição que compreende uma molécula polinucleotídica e uma preparação de organossilicone na fai- xa de cerca de 0.015 a cerca de 2 por cento em peso (% em peso) (p. ex., cerca de 0.01, 0.015, 0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05,
0.055, 0.06, 0.065, 0.07, 0.075, 0.08, 0.085, 0.09, 0.095, 0.1, 0.2, 0.3,
0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9,
2.0, 2.1, 2.2, 2.3, 2.5% em peso) são utilizadas ou providas.
[0042] Preparações de organossilicone utilizadas nos métodos e composições providos aqui podem compreender um ou mais compos- tos de organossilicone eficazes. Como usado aqui, a frase "composto de organossilicone eficaz" é usada para descrever qualquer composto de organossilicone que encontra-se em uma preparação de organossi- licone que permite um polinucleotídeo entrar numa célula de planta. Em certas modalidades, um composto de organossilicone eficaz pode habilitar um polinucleotídeo a entrar numa célula de planta de uma forma que permita uma supressão mediada por polinucleotídeo da ex- pressão de um gene alvo na célula de planta. Em geral, compostos de organossilicone eficazes incluem, mas não estão limitados a, compos- tos que podem compreender: i) um grupo de cabeça trisiloxano que é covalentemente ligado a, ii) um ligante alquil, incluindo, mas não limi- tado a, um ligante n-propil, que é covalentemente ligado a, ili) uma ca- deia de poliglicol, que é covalentemente ligada a, iv) um grupo termi- nal. Grupos de cabeça trisiloxano de tais compostos de organossilico- ne eficazes incluem, mas não estão limitados a, heptametiltrisiloxano. Ligantes alquil podem incluir, mas não estão limitados a, um ligante n- propil. Cadeias de poli glicol incluem, mas não estão limitados a, polie- tilenoglicol ou polipropileno glicol. Cadeias de poli glicol podem com-
preender uma mistura que provê um comprimento de cadeia médio "n" de cerca de "7.5". Em certas modalidades, o comprimento de cadeia médio "n" pode variar de cerca de 5 a cerca de 14. Grupos terminais podem incluir, mas não estão limitados a, grupos alquil, tais como um grupo metil. Acredita-se que compostos de organossilicone eficazes incluem, mas não estão limitados a, tensoativos de etoxilato de trisilo- xano ou heptametil trisiloxano modificado por óxido de polialquileno. + De To NOS >
[0043] (Composto |: polialquilenóxido heptametiltrisiloxano, média n=7.5).
[0044] Em certas modalidades, uma preparação de organossilico- ne que compreende um composto de organossilicone compreendendo um grupo de cabeça trisiloxano é usada nos métodos e composições providos neste documento. Em certas modalidades, uma preparação de organossilicone que compreende um composto de organossilicone compreendendo um grupo de cabeça heptametiltrisiloxano é usada nos métodos e composições providos neste documento. Em certas modalidades, uma composição de organossilicone que compreende o Composto | é usada nos métodos e composições providos neste do- cumento. Em certas modalidades, uma composição de organossilicone que compreende o Composto | é usada nos métodos e composições providos neste documento. Em certas modalidades dos métodos e composições providos aqui, uma composição que compreende uma molécula polinucleotídica e um ou mais compostos de organossilicone eficazes na faixa de cerca de 0.015 a cerca de 2 por cento em peso (% em peso) (p. ex., cerca de 0.01, 0.015, 0.02, 0.025, 0.03, 0.035, 0.04,
0.045, 0.05, 0.055, 0.06, 0.065, 0.07, 0.075, 0.08, 0.085, 0.09, 0.095,
0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6,
1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.5% em peso) é utilizada ou provida.
[0045] Composições incluem mas não são componentes limitados que são um ou mais polinucleotídeos essencialmente idênticos a, ou essencialmente complementares a uma sequência do gene ACCase (promotor, intron, exon, região não traduzida 5', região não traduzida 3'), um agente de transferência que provê para o polinucleotídeo entrar na célula de planta, um herbicida que complementa a ação do polinu- cleotídeo, um ou mais herbicidas adicionais que ainda reforçam a ati- vidade do herbicida da composição ou provêm um modo adicional de ação diferente do herbicida de complementação, vários sais e agentes de estabilização que aumentam a utilidade da composição como uma admistura dos componentes da composição.
[0046] Os métodos incluem uma ou mais aplicações de uma com- posição de polinucleotídeo e uma ou mais aplicações de um agente de melhoria de permeabilidade para o condicionamento de uma planta à permeação por polinucleotídeos. Quando o agente para o condiciona- mento a permeação é uma composição ou composto de organossili- cone nele contida, modalidades das moléculas polinucleotídicas são oligonucleotídeos de RNA de filamento duplo, oligonucleotídeos de RNA de filamento único, polinucleotídeos de RNA de filamento duplo, polinucleotídeos de RNA de filamento único, oligonucleotídeos de DNA de filamento duplo, oligonucleotídeos de DNA de filamento único, poli- nucleotídeos de DNA de filamento duplo, polinucleotídeos de DNA de filamento único, oligonucleotídeos ou polinucleotídeos de RNA ou DNA quimicamente modificados ou suas misturas.
[0047] Composições e métodos são úteis para modular a expres- são de um gene endógeno ACCase (por exemplo, Pat. US No. 7,297,541, Publ. de Patente US 20110185444 e 20110185445) ou ge-
ne ACCase transgênico (por exemplo, Patente US No: 7,3072,379, Publ. de patente US 20110191897) ou genes de inativação de inibidor de ACCase (Pat. US N. º 6.268.549; 6.768.044; 7,3072,379; 7,304,209; WO 96/38567 WO 99/24585) em uma célula de planta. Em várias modalidades, um gene ACCase inclui sequência codificadora (codificadora de proteínas ou traduzível), sequência não codificadora (não-traduzível) ou ambas a sequência codificadora e não-codifica- dora. Composições da invenção podem incluir polinucleotídeos e oli- gonucleotídeos projetados para direcionar múltiplos genes ou múltiplos segmentos de um ou mais genes. O gene alvo pode incluir múltiplos segmentos consecutivos de um gene alvo, múltiplos segmentos não- consecutivos de um gene alvo, múltiplos alelos de um gene alvo, ou múltiplos genes-alvo de uma ou mais espécies.
[0048] Um aspecto da invenção provê um método para modular a expressão de um gene ACCase em uma planta incluindo (a) condicio- namento de uma planta à permeação por polinucleotídeos e (b) trata- mento da planta com as moléculas polinucleotídicas, em que as molé- culas polinucleotídicas incluem pelo menos um segmento de 18 ou mais nucleotídeos contíguos clonados a partir de ou identificados de outra forma a partir do gene ACCase alvo ou em orientação anti-senso ou senso, por onde as moléculas polinucleotídicas permeiam o interior da planta e induzem modulação do gene alvo. O condicionamento e aplicação de polinucleotídeo podem ser desempenhados separada- mente ou em uma única etapa. Quando o condicionamento e aplica- ção de polinucleotídeo são desempenhados em etapas separadas, o condicionamento pode preceder ou pode seguir a aplicação de polinu- cleotídeo dentro de minutos, horas ou dias. Em algumas modalidades mais de uma etapa de condicionamento ou mais de uma aplicação de molécula polinucleotídica pode ser desempenhada na mesma planta. Em modalidades do método, o segmento pode ser clonado ou identifi-
cado a partir de (a) codificação (codificação de proteína), (b) não- codificação (promotor e outras moléculas relacionadas a genes), ou (c) tanto partes de codificação quanto de não codificação do gene alvo. Partes não-codificantes incluem DNA, tais como regiões de promotor ou o RNA transcrito por DNA que provêm moléculas reguladoras de RNA , incluindo mas não limitadas a: introns, regiões não traduzidas 5' ou 3' e microRNAs (mIiRNA), siRNAs de trans ação, siRNAs anti-senso naturais e outros pequenos RNAs com função reguladora ou RNAs tendo função estrutural ou enzimática incluindo mas não limitado a: ribozimas, RNAs ribossômicos, t-RNAs, aptâmeros e ribocomutadores.
[0049] Todas as publicações, patentes e pedidos de patente estão incorporados neste documento por referência na mesma medida como se cada publicação ou pedido de patente individual fosse indicado es- pecificamente e individualmente para ser incorporado por referência.
[0050] Os exemplos a seguir estão incluídos para demonstrar e- xemplos de certas modalidades preferenciais da invenção. Deve ser entendido por aqueles versados na técnica que as técnicas divulgadas nos exemplos que se seguem representam abordagens que os inven- tores encontraram função bem na prática da invenção e, portanto, po- dem ser consideradas para constituírem exemplos de modos preferen- ciais para a sua prática. No entanto, aqueles versados na técnicade devem, à luz da presente divulgação, apreciar que muitas mudanças podem ser feitas nas modalidades específicas que são divulgadas e ainda obter um resultado igual ou similar sem se afastar do espírito e o escopo da invenção.
EXEMPLOS Exemplo 1 Polinucleotídeos relacionados com as sequências de gene ACCase.
[0051] A molécula polinucleotídica de ACCase alvo ocorre natu- ralmente no genoma de Amaranthus palmeri, Amaranthus rudis, Ama-
ranthsu chlorostachys, Amaranthus thunbergii, Amaranthusgraecizans, Amaranthus hybridus, Amaranthus lividus, Amanaranthus spinosus, , Abutilon theophrasti, Ambrosia trifida, Commelina diffusa, Conyza can- densis, Lolium multiflorum, Sorghumhalepense, Xanthium strumarium, Euphorbia heterophylla, Kochia scoparia e Digitaria sanguinalis e in- cluem moléculas relacionadas com a expressão de um polipeptídeo identificado como um ACCase, que incluem moléculas reguladoras, cCDNAs compreendendo suas regiões codificantes e não codificantes de um gene ACCase e fragmentos, conforme mostrado na tabela 1.
[0052] Moléculas polinucleotídicas foram extraídas destas espé- cies de plantas por métodos padrão no campo, por exemplo, RNA total é extraído usando o Reagente Trizol (Invitrogen Corp, Carlsbad, CA. Cat. No. 15596-018), seguindo o protocolo do fabricante ou modifica- ções respectivas por aqueles hábeis na técnica da extração polinu- cleotídica que pode melhorar a recuperação ou a pureza do RNA ex- traído. Brevemente, comece com 1 grama de tecido de planta triturado para extração. Transfira uma pré-alíquota de 10 mililitros (mL) de Rea- gente de Trizol para tubos cônicos de 15 mL. Adicione o pó triturado a tubos e agite para homogeneizar. Incube as amostras homogeneiza- das por 5 minutos (min) a temperatura ambiente (RT) e em seguida adicione 3 mL de clorofórmio. Agite os tubos vigorosamente à mão du- rante 15-30 segundos (seg) e incube a RT por 3 min. Centrifugue os tubos a 7.000 rotações por minuto (rpm) durante 10 minutos a 4 graus C. Transfira a fase aquosa para um novo tubo de 1,5 mL e adicione 1 volume de isopropanol frio. Incube as amostras durante 20-30 min a RT e centrifugue a 10.000 rpm durante 10 minutos a 4 graus C. Lave o pellet com etanol da 80 por cento grau Sigma. Remova o sobrenadan- te e secar brevemente o pellet. Dissolva a pelota do RNA em aproxi- madamente 200 microlitros de água tratada DEPC. Aqueça brevemen- te em 65 graus C para dissolver o pellet e vortex ou pipeta para res-
suspender o RNA. Ajuste a concentração de RNA para 1-2 microgra- ma/microlitro.
[0053] DNA foi extraído utilizando EZNA SP planta DNA Mini kit (Omega Biotek, Norcross, GA, Cat tD5511) e tubos Lysing Matrix E (Q-Biogen, Cattt6914), seguindo o protocolo do fabricante ou modifica- ções respectivas por aqueles versados na técnica da extração de poli- nucleotídeo que pode melhorar a recuperação ou a pureza do DNA extraído. Brevemente, tecido de chão de alíquota para um tubo Lysing Matrix E em gelo seco, adicionar 800ul SP1 de tampão para cada a- mostra, homogeneizar em um batedor do grânulo para 35-45seg, in- cubar no gelo por 45-60 seg, centrifugar a 214000 rpm durante Imin a RT, adicionar 10 microlitros de RNase A para o lisado, incubar a 65'C por 10min, centrifugar por Imin em RT, adicionar 280ul de Tampão de SP2 e vórtice para misturar, incubar as amostras no gelo por 5min, centrifugar em > 10.000g por 10min a RT, transferir o sobrenadante para uma coluna de homogeneizador em um tubo de coleta de 2ml, centrifugação a 10.000 g por 2min em RT, transferir o lisado depurado em um tubo de microcentrífuga de 1,5 ml, adicionar 1,5 volumes de Tampão de SP3 para o lisado depurado, vórtice imediatamente para obter uma mistura homogénea, transferir até 650ul de sobrenadante à coluna Hi-Bind, centrifugar em 10.000 g por imin, repetir, aplicar 100 pl de tampão de eluição a 65'C à coluna, centrifugação em 10.000 g durante 5min à RT
[0054] Sequenciadores de DNA de última geração, tais como a 454-FLX (Roche, Branford, CT) e o SOLID (Applied Biosystems), e o analisador de genoma Genome Analyzer (HiSeg2000, Illumina, San Diego, CA) foram usados para prover a sequência polinucleotídica do DNA e do RNA extraída de tecidos de plantas. Dados de sequência brutos são montados em contigs. A sequência de contig é usada para identificar moléculas desencadeadoras que podem ser aplicadas à planta para permitir a regulação da expressão do gene. A sequência de DNA alvo isolada do DNA genômico (gDNA) e codificante (CDNA) das várias espécies de planta com ervas daninhas para o gene de ACCase e os contigs montados conforme exibido nas SEQ ID NOs 1- 93 e Tabela 1.
Exemplo 2. Polinucleotídeos da invenção relacionada com as molécu- las desencadeadoras
[0055] As sequências de genes e fragmentos da Tabela 1 foram divididas em 200 comprimentos polinucleotídicos (200-mer) com 25 regiões sobrepostas de polinucleotídeos (SEQ ID NO:93-3900). Estes polinucleotídeos são testados para selecionar as regiões desencadea- doras mais eficazes em todo o comprimento de qualquer sequência alvo. Os polinucleotídeos desencadeadores são construídos como SSDNA ou ssRNA, dsRNA, ou dsDNA ou híbridos de dsDNA/RNA sen- so ou anti-senso e combinados com um agente de transferência à ba- se de organossilicone para prover uma preparação polinucleotídica. Os polinucleotídeos são combinados em conjuntos de dois a três poli- nucleotídeos por conjunto, usando 4-8 nmol de cada polinucleotídeo. Cada conjunto de polinucleotídeo é preparado com o agente de trans- ferência e aplicado a uma planta ou um campo de plantas em combi- nação com um herbicida contendo inibidor de ACCase ou seguido por um tratamento de inibidor de ACCase um a três dias após a aplicação de polinucleotídeo, para determinar o efeito sobre a suscetibilidade da planta a um inibidor de ACCase. O efeito é medido como diminuindo o crescimento e/ou morte da planta e é medido 8-14 dias após o trata- mento com o conjunto de polinucleotídeo e inibidor de ACCase. Os conjuntos mais eficazes são identificados e os polinucleotídeos indivi- duais são testados nos mesmos métodos como os conjuntos são e identificados de 200-mer mais eficazes. A sequência de 200-mer é di- vidida em sequências menores de regiões de 50-70-mer com 10-15 regiões sobrepostas polinucleotídicas e os polinucleotídeos testados individualmente. O 50-70-mer mais eficaz é ainda dividido em sequên- cias menores das regiões de 25-mer com uma região de sobreposição de polinucleotídeo 12 a 13 e testado para eficácia em combinação com tratamento com inibidor de ACCase. Por esse método é possível iden- tificar um oligonucleotídeo ou vários oligonucleotídeos que são a mo- lécula desencadeadora mais eficaz para efetuar sensibilidade de plan- ta a um inibidor de ACCase ou modulação da expressão de um gene ACCase. A modulação da expressão do gene ACCase é determinada pela detecção de moléculas de siRNA de ACCase específicas para gene de ACCase ou por uma observação de uma redução na quanti- dade de transcript de RNA de ACCase produzida em relação a uma planta não tratada ou simplesmente observando o fenótipo antecipado da aplicação do desencadeador com o herbicida contendo inibidor de ACCase. Deteção de siRNA pode ser realizada, por exemplo, usando kits tais como mirVana (Ambion, Austin TX) e mirPremier (Sigma- Aldrich, St. Louis, MO).
[0056] A sequência de DNA alvo isolada do DNA genômico (gD- NA) e codificador (CDNA) das várias espécies de planta com ervas da- ninhas para o gene de ACCase e os contigs montados conforme exibi- do nas SEQ ID NOs 1-92 foram divididos em fragmentos de polinucle- otídeo como mostrado na SEQ ID NOs 93-3900.
[0057] As sequências de gene e fragmentos da Tabela 1 foram comparados e 21-mers de polinucleotídeos contíguos foram identifica- dos que tiveram homologia ao longo de várias sequências de gene de ACCase. O propósito é identificar moléculas desencadeadoras que são úteis como moléculas herbicidas ou em combinação com um her- bicida inibidor de ACCase ao longo de uma ampla faixa de espécies com ervas daninhas. As sequências SEQ ID NOs 3901-4530 represen- tam os 21-mers que estavam presentes no gene de ACCase de pelo menos oito das espécies de ervas daninhas da Tabela 1. É contem- plado que 21-mers adicionais podem ser selecionados de sequências da Tabela 1 que são específicas para uma espécie de erva daninha única ou algumas espécies de ervas daninhas dentro de um gênero ou moléculas desencadeadoras que são pelo menos 18 nucleotídeos con- tíguos, pelo menos 19 nucleotídeos contíguos, pelo menos 20 nucleo- tídeos contíguos ou pelo menos 21 nucleotídeos contíguos em com- primento e pelo menos 85 por cento idênticos a uma sequência do ge- ne de ACCase selecionada do grupo constituído por SEQ ID NO: 1-92 ou fragmento da mesma.
[0058] Por esse método é possível identificar um oligonucleotídeo ou vários oligonucleotídeos que são a molécula desencadeadora mais eficaz para efetuar sensibilidade de planta a um inibidor de ACCase ou modulação da expressão de um gene ACCase. A modulação da ex- pressão do gene ACCase é determinada pela detecção de moléculas de siRNA de ACCase específicas para gene de ACCase ou por uma observação de uma redução na quantidade de transcript de RNA de ACCase produzida em relação a uma planta não tratada ou simples- mente observando o fenótipo antecipado da aplicação do desencade- ador com o herbicida contendo inibidor de ACCase. Deteção de siRNA pode ser realizada, por exemplo, usando kits tais como mirVana (Am- bion, Austin TX) e mirPremier (Sigma-Aldrich, St. Louis, MO).
[0059] A sequência de DNA alvo isolada do DNA genômico (gD- NA) e codificador (CDNA) das várias espécies de planta com ervas da- ninhas para o gene de ACCase e os contigs montados conforme exibi- do nas SEQ ID NOs 1-92 foram divididos em fragmentos como mos- trado na SEQ ID NOs 3901-4530.
[0060] Exemplo 3. Métodos utilizados na invenção relacionados com plantas de tratamento ou partes da planta com uma mistura tópica das moléculas desencadeadoras.
[0061] Plantas de amaranto Palmer sensíveis a glifosato (A. pal- meri R-22) onde foram cultivadas em estufa (30/20 C dia/noite T; 14 horas de fotoperíodo) em potes quadrados de 4 polegadas contendo Sun Gro & Redi-Earth e 3,5 kg/metro cúbico de fertilizante Osmocote& 14-14-14. Plantas de palmer amaranto em 5 a 10 cm de altura foram previamente tratadas com um pool de 8 polinucleotíceos de DNA de oligo antisenso de filamento único curto (21-22mer) (ssSDNA), direcio- nando ACCase na tabela 2 em 16 nmol, formulado em 10 minimolar de tampão fosfato de sódio (pH 6,8) contendo 2% de sulfato de amônio e 0,5% de Silwet L-77. As plantas foram tratadas manualmente por pipe- tagem de 10 ul de solução polinucleotídica em quatro folhas maduras totalmente expandidas, para um total de 40 microlitros de solução por planta. Vinte e quatro e quarenta e oito horas mais tarde, as plantas foram tratadas com cletodim (SelectMax &, 0,97 |b ai por galão; Inibi- dor da ACCase) em 272 g ia/ha, concentrado de óleo de cultivo (COC) a 1% foi adicionado para os tratamentos de herbicida. Quatro repeti- ções de cada tratamento foram conduzidas. Altura de planta é deter- minada logo antes do tratamento com ssDNA e em intervalos de até doze dias após tratamentos com herbicida para determinar o efeito dos tratamentos com oligonucleotídeo e herbicida.
Tabela 2. Oligonucleotídeos de ACCase de ssSDNA
[0062] Os resultados dos tratamentos são mostrados na Figura 1 e demonstrados que as plantas tratadas com 16 nmo!l e o herbicidas de cletodim provocaram redução de 22% na altura da planta em relação ao controle não tratado e cletodim sozinho provocou redução de 0% na altura de planta. Resultado surpreendente, considerando que plan- tas de dicot não são normalmente sensíveis a herbicidas de inibidor de ACCase.
[0063] Um teste adicional foi conduzido para determinar qual dos oligonucleotídeos ACCase foi responsável para o resultado. Neste tes- te, cada oligonucleotídeo foi aplicado a quatro plantas em 4 nmol (na- nomol) por planta, o herbicida foi aplicado 24 horas após o tratamento do oligonucleotídeo e as plantas foram avaliadas para efeitos de cres- cimento. Este teste de seguimento identificou aquele oligo6 formulado (SEQ ID NO: 4536) teve o maior efeito e foi capaz de reduzir o cresci- mento da planta por e média de 40 por cento em relação a plantas não tratadas. Este resultado provê uma oportunidade para ampliar o es- pectro do uso para herbicidas de inibidor ACCas para incluir ervas da- ninhas dicot. Exemplo 4. Um método para controlar ervas daninhas em um campo.
[0064] Um método para controlar ervas daninhas em um campo compreende o uso de polinucleotídeos desencadeadores que pode modular a expressão de um gene de ACCase em uma ou mais espé- cies de plantas de erva daninha alvo. Uma análise de sequências de gene de ACCase de dezessete espécies de plantas proveu uma cole- ção de polinucleotídeos de 21-mer que pode ser usada em composi- ções para afetar o crescimento ou desenvolvimento ou sensibilidade ao herbicida inibidor de ACCase para controlar múltiplas espécies de ervas daninhas em um campo. Uma composição contendo 1 ou 2 ou 3 ou 4 ou mais dos polinucleotídeos de SEQ ID NO: 3901-4530 permiti- ria atividade ampla da composição contra as várias espécies de ervas daninhas que ocorrem em um ambiente de campo.
[0065] O método inclui a criação de uma composição que compre- ende componentes que incluem pelo menos um polinucleotídeo do
SEQ ID NO: 3901-4530 ou qualquer outro polinucleotídeo de modula- ção de expressão de gene eficaz essencialmente idêntico ou essenci- almente complementar à SEQ ID NO : 1-92 ou fragmento da mesma, um agente de transferência que mobiliza o polinucleotídeo em uma célula de planta e um herbicida de inibição de ACCase e opcionalmen- te um polinucleotídeo que modula a expressão de um gene essencial e, opcionalmente, um herbicida que tem um modo diferente de ação em relação a um inibidor de ACCase. O polinucleotídeo da composi- ção inclui um dsRNA, ssDNA ou dsDNA ou uma combinação destes. Uma composição contendo um polinucleotídeo pode ter uma taxa de utilização de cerca de 1 a 30 gramas ou mais por acre, dependendo do tamanho do polinucleotídeo e do número de polinucleotídeos na com- posição. A composição pode incluir um ou mais herbicidas adicionais conforme necessário para prover controle de erva daninha de multí- plas espécies eficaz. Um campo de plantas de cultivo em necessidade de controle de erva daninha é tratado pela aplicação por pulverização da composição. A composição pode ser provida como uma mistura de tanque, um tratamento sequencial de componentes (geralmente o po- linucleotídeo seguido pelo herbicida), um tratamento simultâneo ou mistura de um ou mais dos componentes da composição a partir de recipientes separados. Tratamento do campo pode ocorrer tantas ve- zes quanto necessário para prover controle de ervas daninhas e os componentes da composição podem ser ajustados para visar espécies de ervas daninhas específicas ou famílias de ervas daninhas. Tabela 1. Sequências de genes ACCase isoladas de espécies de planta com ervas daninhas SEQ [ESPÉ- |[TI- lCOM- |SEQ IDNO |[CIES PO |PRI- MEN-
TOH
1 Abutilon |cD- 1036 TTGCTGTAACTGATCTTGCCTGCA theop- NA- GTAAGAAACTGCCTTTAATTTATTT hrasti Con- GGCTGCGAACTCTGGTGCTCGTA tig TTGGGGTAGCTGAAGAAGTCAAA
GCCTGCTTTAAAGTTGGTTGGTCT GATGAATCCAGCCCTGAGCGTGG TTTTCAGTACATTTACATAACTCCT GAGGATTATACTAGGATTGGATCA TCGGTCATTGCACATGAGATGAAG CTGGCCAGTGGAGAGAGCAGATG GGTGATAGATACTATTGTTGGGAA GGAGGATGGTTTGGGGGATCGAG AACTTAACAGGTAGTGGAGCCATT GCTGGTGCATACTCTCGGGCATA CAAAGAAACCTTTACCCTAACGTA TGTGACTGGTAGAACTGTGGGAA TTGGTGCTTATCTTGCTCGTCTTG GCATGCGGTGTATACAAAGACTC GATCAACCCATTATTTTGACTGGT TTCTCAGCATTGAACAAACTTCTA GGTCGTGAGGTGTATAGCTCCCA CATGCAACTTGGTGGACCTAAAAT CATGGCAACAAATGGGGTGGTTC ATCTCACCGTCTCAGATGATCTTG AAGGGGTGTCAGCTATTTTGAACT GGATAAGTTGCATACCTCCTCATA TTGGTGGTCCACTTCCCATTTTAA ACCCATCAGATCCTCCAGAAAGG CCTGTGGAGTACATCCCGGAAAA TTCATGTGATCCTCGTGCCGCTAT TTGTGGTGCTTTAGATAGTAATGG CAAGTGGAAGGGCGGTATTTTTG ACAGGGATAGCTTTGTGGAGACG CTCGAAGGTTGGGCTAGAACAGT TGTCACAGGAAGGGCAAAGCTTG GAGGAATTCCTGCAGGAATAGTT GCAGTTGAGACACAGACGGTGAT GCAGGTTATCCCTGCCGATCCAG GACAACTTGATTCCCATGAAAGAG TTGTCCCTCAAGCTGGACAGGTAT GGTTTCCGGATTCTGCTACAAAGA CAGCTCAGGCAATAATGGATTTCA ACAGGGAAGAGCTTCCACTTTTCA
TTCTTGCCAATTGGAGAGGCT 2 Amaran- |cD- |1479 ACCACGAGAAGATGCTTTCTTCCT thus gra- | NA- TGCGGTTACAAATCTTGCTTGTGC ecizans Con- GAAGAAACTTCCTCTTATTTATCT tig GGCTGCAAATTCAGGAGCTCGAC
TTGGTGTTGCCGAAGAGCTAAAAT CCTGCTTTAAAGTTGGCTGGTCG GATGAGTCAAACCCCGAGAGTGG ATTTCAGTATGTCTTCTTAACCCC GGAAGATTACGATCGTATCGGATC GTCAGTCATAGCCCACGAGTTAAA ACTCGAAAGTGGAGAAAAAAGAT GGGTTATAGACACAGTTGTCGGA AAGGAGGACGGATTAGGTGTCGA GAATCTATCAGGAAGTGGTGCTAT AGCCAGTGCATACTCAAGGGCTT ACAAGGAAACATTTACTCTGACTT TTGTAACTGGTAGAACGGTCGGTA TTGGTGCCTATCTTGCTCGCCTTG GGATGCGTTGTATACAGAGGCTT GACCAGCCTATAATTCTCACGGGT TTTTCTGCGTTAAATAAACTTCTTG GTCGGGAGGTTTACAGTTCACAC ATGCAACTTGGTGGACCGAAGATT ATGGGCACAAACGGGGTAGTTCA TCTTACAGTTTCCGATGATCTTGA AGGCATTTCATCTATCTTGAAGTG GCTGAGCTATGTTCCACCCTATGC AGGTGGTGAACTTCCGATTTCTCG GTGTTTAGACCCTCCAGAAAGACC CGTTGCGTATTTGCCTGAAAATTC TTGTGATCCTCGTGGTGCTATATC TGGTACAGTTGACTCCACCGGTAA ATGGCATGGGGGTATTTTCGACAA GGATAGTTTTGTGGAAACCTTAGA AGGCTGGGCACGAACAGTTGTCA CGGGAAGGGCTAAACTTGGAGGA ATTCCAGTTGGGATAGTTGCCGTT GAGACGCAGACTGTTATGCAAGT AATCCCAGCAGATCCCGGTCAAC TCGACTCACACGAGAGAGTCGTA CCACAAGCAGGGCAAGTATGGTT CCCAGATTCCGCATCCAAGACAG CACAAGCGCTGATGGATTTCAACC GGGAAGAACTACCACTTTTCATTT TAGCTAATTGGAGAGGTTTCTCGG GTGGACAAAGGGATCTCTTTGAA GGGATCCTTCAAGCCGGATCCAC CATTGTCGAAAATCTTAGGACTTA TAATCAACCCGTTTTTGTTTATATA CCAATGATGGGGGAGCTTCGAGG AGGCGCATGGGTGGTCGTGGATA GTCGAATTAATTCCGATCATATAG AAATGTACGCCGACCAAACAGCTA AAGGAAATGTGCTTGAACCCGAA GGAATGATCGAGATTAAGTTCAGA ACCAAGGAACTTCTCGAGTGTATG GGAAGGCTTGATCAACAACTCATC GGTCTCAAGGAAAAACTAGCAGA AGCCAAGAGCTCTAATTCCTACGA TAAAATCGACCCCCTGCAGCAACA AATAAAAGCCCGCGAGAAGCAAC TATTGCCTCTATATACTCAGA-
TAGCCACCAAATTTGC 3 Amaran- !|cD- /638 AAATATACTCCTTCCCGTGATCGT thus gra- | NA- CAATGGCATCTTTACACGGTTATT ecizans Con- GATAAACCACTCATTCGGAGGATG tig TTTTTGAGAACCCTTGTAAGACAA
CCCATCTCTGAGTTCACAGGCGT CGAACTAAGCGCTCTTGAAACACA AAAGCCCATCTCTTTTACTTCAAG AAGCATCCTAAGGTCCTTAACAAC CGCCATGGAGGAGTTGGAACTCA ATGCACATAGTGCTTCATTGAAAC CCGATCACGCTCATATGTACTTGT ACATTGTTCGAGAGCAACAAATAT ACGATCTTGTGCCATATCACAGGG AGGTGAACATAGATTACCAACAAG AAGAGGCTTCGGTTCAATTCTTTT TGGAAGAGCTCGCGCATGAAATC CACAGTCTTGCTGGTGTAAGGAT GCATAAACTAAATGTTTGTGAGTG GGAAGTGAAACTTCGGATATCTTC TCCCGGGAAAGCTAATGGTTTATG GAGGGTGGCGGTTACTAATGTGA CTGGTCAGACCTGTTCGGTACAT GTTTATCGTGAATTGGAAGATAGC AACCTACATGAAATGGTCTACCAT TCATTATCCGTTCACGGTCCCCAC CATGGGGTACCTGTGAATGCACC
CTATCAACCACTAGGTGGCAT 4 Amaran- |cD- |2174 TGAACATAGATTACCAACAAGAAG thus hy- | NA- AGGCTTCGGTTCAATTCTTITTTGG bridus Con- AAGATCTCGCGCATGAAATCCATA tig GTCTTGCTGGTGTAAGGATGCATA
AACTAAATGTTTGTGAGTGGGAAG TGAAACTTCGGATATCATCTCCCG GGAAAGCTAATGGTTTATGGAGG GTGGCAGTTACTAATGTGACTGGT CATACCTGTTCGGTACATGTTTAT CGTGAATTGGAAGATAGCAACCTA CATGAAATGGTCTACCATTCAGTA TCTGTTCACGGCCCCCACCATGG GGTACCTGTGAATGCACCCTATCA ACCACTCGGTGGCATCTCCCGTA AGCGACTTCAGGCCATGAAGAGT AGCACAACATACTGTTACGATTTT CCACTGGCTTTCTCAACTGCCCTG AAGCAATCATGGGCATCGGAAGC TCCGGATGTCAAGAAACCCTCGG ACAAAGCACTTTTGAAAGTAACCG AGCTAGCATTTGCTGATCCAAAAG GCACATGGGGAACTCCGCTTGTT CCAATAAATCGCAAGCCTGGTATG AACGATGTTGGCATGGTAGCCTG GTACTTGGAAATGTCCACCCCCG AGTTCCCTAACGGAAGAACAATAA TGGTTGTAGCTAATGATGTTACCT TCAAGGCCGGATCTTTCGGACCA CGAGAAGATGCTTTCTTCCTTGCT GTTACAAATCTTGCTTGCGCGAAG AAACTTCCTCTTATTTATCTGGCT GCCAATTCAGGAGCTCGACTTGG TGTTGCCGAAGAGCTAAAATCCTG CTTTAAAGTTGGCTGGTCGGATGA GTCAAACCCCGAGAGTGGATTTC AGTATGTCTACTTAACCCCTGAAG ATTACGATCGTATAGGATCGTCAG TCATAGCCCACGAGTTAAAACTCG AAAGTGGAGAAAAAAGATGGGTTA TAGACACCGTTGTCGGTAAGGAG GACGGATTAGGTGTCGAGAATCT ATCAGGAAGTGGTGCTATAGCCA GTGCATACTCAAGGGCTTACAAG GAAACATTTACTCTGACTTTTGTAA CCGGTAGAACGGTCGGTATTGGT GCCTATCTTGCTCGTCTTGGGATG CGTTGTATACAGAGGCTTGACCA GCCTATAATTCTCACGGGTTTTTC TGCGTTAAATAAACTTCTCGGTCG GGAGGTTTACAGTTCACACATGCA ACTTGGTGGACCGAAGATAATGG GCACAAACGGGGTAGTTCATCTTA CAGTTTCCGATGATCTTGAAGGCA TTTCATCTATCTTGAAGTGGCTGA GCTATGTTCCACCCTATTCAGGTG GTGAACTTCCGATTTCTCGGTGTT TAGACCCTCCCGAAAGACCGGTT GCGTATTTGCCTGAAAATTGTTGT GATCCTCGTGGGGCTATATCTGG TACGGTTGACTCCGCCGGTAAAT GGTTTGGGGGTATTTTCGACAAG GATAGTTTTGTGGAAACCTTAGAA GGATGGGCACGAACAGTTGTCAC GGGAAGGGCTAAACTCGGAGGAA TTCCAGTTGGCATAGTTGCTGTTG AGACACAGACTGTTATGCAAGTAA TCCCAGCAGATCCCGGTCAACTC GACTCACATGAGAGAGTCGTACC ACAAGCAGGGCAAGTATGGTTCC CAGATTCCGCATCCAAGACAGCA CAAGCGCTGATGGATTTCAACCG GGAAGAACTCCCACTTTTCATTIT AGCTAATTGGAGAGGTTTCTCGG GTGGACAAAGGGATCTCTTTGAA GGGATCCTTCAGGCTGGATCCAC CATAGTCGAAAATCTTAGGACTTA TAATCAACCCGTTTTTGTTTATATC CCTATGATGGGGGAGCTTCGAGGÇ AGGCGCATGGGTGGTCGTCGATA GTCGAATTAATTCCGACCATATAG AAATGTACGCCGACCAAACAGCTA AAGGAAATGTGCTTGAACCGGAA GGAATGATCGAGATTAAGTTCCGA ACCAAGGAACTTCTCGAGTGTATG GGAAGGCTTGACCAACAACTCAT CGGTCTCAAGGAAAAACTAGCCG AAGCCAAGAGCTCTAATTCCTACG ATAAAATCGAGCCCCTGCAGCAA CAAATAAAAGCCCGCGAGAAGCA ACTATTGCCTCTTTATACTCAGATA GCCACCAAATTTGCCGAGTTGCAT GATACGTCTTTAAGGATGGCTGC-
CAAA Amaran- |cD- /530 CACTCGTCAAGACTGTTCGAGATG thus hy- | NA- CTGCAGGTGAACGGTTGACCCAT bridus Con- AAGTCGGCTTTGGAGTTGATCCG tig GAAATGGTTCAATGAGTCAGATAT
TTCCGGAGAGGCTTCCGATGCTT GGGCTGATGATGCGACCTTCTTTA AGTGGAAGGACAATACCGCTAAC TACGAGGAGAAGTTGAAAGAGTT GCGGGTTCAGAAGGTATTGGATC AGCTGTCGAATATTGGAGATTCGG TAACTAATTTGAGGGCTCTGCCTC AGGGTCTTGCTGCCCTACTTCAAA AGGTGGATCCATCGAGTCGAGAA GAACTAGTCGAGGAACTCCGAAA AGTGCTCACTTGATTTCGCAACCG TTGATGGTGAAGTGAAACCTTCTT GGTTTCATCATGGTAGAAAATATT ATTAGGCAAATCTATAATTTITTAGT GACATCAATTGTTTTAGACAATAG TATTGAACTAATTTATTTAATTAAA TTGTATAAATAGGAGACCTTGAAT TCATTTGAATTAAGTGGCT-
TATGCTTGCATTA Amaran- |cD- |527 TATAGATGAAGTAGTACAGAGTTT thus hy- | NA- GCTGGAATGCCTTGATAGTCCCG bridus Con- AACTTCCATTCCTTCAATGGCAAG tig AATGCTTGTCTGTGCTGGCAACAC
GACTTCCCAAAGATCTGAGATACG AATTGGAATCAAAATCTAGAGCTT TTGAAGGGATTACCAACACCCAGA ACGTAGAATTTCCTGCTAAGTTGT TGAAAAGCATTCTTGAGGACCATT TAAACTCATGCCACGAGAAAGATA AAGGAGCTCAAGAGAGGCTTATT GAGCCTCTTATGGCTCTTGTAAAG TCTTACGAAGGTGGGCGAGAAAG TCATGCTCGTTTTATTGTTCAATCOT TTATTTGAAGAGTATTTATCCGTTG AAGAATTGTTTAGCGACAATCTCC AGGCTGATGTGATTGAACGTCTCC GCCTTCAGTATAAGAAGGATCTGC TGAAGATTGTTGACATTGTACTGT CGCATCAGGGTGTTAAGAATAAAA
ATAAGCTGATTCTACGACTCATGG o Ç MeeTcarmTcÇanATESs 7 Amaran- |cD- [1310 CGAGAGTGGATTTCAGTATGTCTA thus liviz- | NA- CTTAACCCCTGAAGATTACGATCG dus Con- TATAGGATCGTCAGTCATAGCCCA tig CGAGTTAAAACTCGAAAGTGGAG
AAAAAAGATGGGTTATAGACACCG TTGTCGGTAAGGAGGACGGATTA GGTGTCGAGAATCTATCAGGAAG TGGTGCTATAGCCAGTGCATACTC AAGGGCTTACAAGGAAACATTTAC TCTGACTTTTGTAACCGGTAGAAC GGTCGGTATTGGTGCCTATCTTGC TCGTCTTGGGATGCGTTGTATACA GAGGCTTGACCAGCCTATAATTCT CACGGGTTTTTCTGCGTTAAATAA ACTTCTCGGTCGGGAGGTTTACA GTTCACACATGCAACTTGGTGGAC CGAAGATAATGGGCACAAACGGG GTAGTTCATCTTACAGTTTCCGAT GATCTTGAAGGCATTTCATCTATC TTGAAGTGGCTGAGCTATGTTCCA CCCTATTCAGGTGGTGAACTTCCG ATTTCTCGGTGTTTAGACCCTCOCC GAAAGACCGGTTGCGTATTTGCCT GAAAATTGTTGTGATCCTCGTGGG GCTATATCTGGTACGGTTGACTCC TCCGGTAAATGGTTTGGGGGTATT TTCGACAAGGATAGTTTTGTGGAA ACCTTAGAAGGATGGGCACGAAC AGTTGTCACGGGAAGGGCTAAAC TCGGAGGAATTCCAGTTGGCATA GTTGCTGTTGAGACGCAGACTGTT ATGCAAGTAATCCCAGCAGATCCC GGTCAACTCGACTCACATGAGAG AGTCGTACCACAAGCAGGGCAAG TATGGTTCCCAGATTCCGCATCCA AGACAGCACAAGCGCTGATGGAT TTCAACCGGGAAGAACTCCCACTT TTCATTTTAGCTAATTGGAGAGGT TTCTCGGGTGGACAAAGGGATCT CTTTGAAGGGATCCTTCAGGCTG GATCCACCATAGTCGAAAATCTTA GGACTTATAATCAACCCGTTTITG TTTATATCCCTATGATGGGGGAGC TTCGAGGAGGCGCATGGGTGGTC GTCGATAGTCGAATTAATTCCGAC CATATAGAAATGTACGCCGATCAA ACAGCTAAAGGAAATGTGCTTGAA CCGGAAGGAATGATCGAGATTAA GTTCCGAACCAAGGAACTTCTCGA GTGTATGGGAAGGCTTGACCAAC AACTCATCGGTCTCAAGGAAAAAC TAGCCGTAGCCAAGAGCTCTAATT CCTACGATAAAATCGAGCCCCTG CAGCAACAAATAAAAGCCCGCGA GAAGCAACTATTGCCTCTTTA-
TACTCAGATAG Amaran- |cD- 1309 AAAGCATTCTTGAGGACCATTTAA dee O [ieveceiocroueas
Con- GAGCTCAAGAGAGGCTTATTGAG tig CCTCTTATGGCTCTTGTAAAGTCOT
TACGAAGGTGGGCGAGAAAGTCA TGCTCGTTTTATTGTTCAATCTTTA TTTGAAGAGTATTTATCCGTTGAA GAATTGTTTAGCGACAATCTCCAG GCTGATGTGATTGAACGTCTCCGT CTTCAGTATAAGAAGGATCTGCTG AAGATTGTTGACATTGTACTGTCG CATCAGGGTGTTAAGAATAAAATA AGCTGATTCTACGACTCATGGAAC AGCTGGTTTACCCAAATCCCGCTG CATACAGGGGGAAACTTATCCGTT TCTCTCAATTGAACCATACAATGT ATTCTGAGTTGGCACTAAAGGCCA GTCAATTGCTTGAACAAACGAAAT TGAGTGAGCTCCGTTCGAACATTG CTAGAAACCTCTCTGAGCTAGAAA TGTTTACCGAGGATGGCGAAAAC ATGGATACTCCAAAAAGAAAAAGT GCTATTAATGAACGTATGGAGGC GCTTGTGAGTACTCCTCTAGCTGT CGAAGATGCCCTTGTTGGTTTGTT TGATCATAGTGATCATACACTTCA GAGGCGGGTTGTTGAGACCTATG TTCGGAGGCTTTATCAGCCTTATC TTGTCAAGGGAAGTGTCAGGATG CTGTGGCACAGATCAGGCTTCATA GCTTTATGGGAATTTGTTGAGGAG AATATTGACCGAACAAATTTITCT GATCTGACTACAAACAGTGGGAA CCATAGTGAGCGAAAGTGGGGGGÇ CCATGGTCGTTATTAAAACTCTTC AGTTCTTGCCATCGGTAATTGCTG CAGCATTGAGAGAAACAACTCATA GTTCCGATCAATCAACTTCCACTG GCTCTATAGAATCAGTCATCCATG GAAATATGCTGCACATTGCACTAG TGGGGGTGAATAACCAGATGAGC TTGTTGCAGGATAGTGGTGATGAA GATCAGGCTCAAGAGAGAATCGA TAAGTTGGCCAAAATTCTGAGAGA ACAAGAAGTGAGTTCAGCCCTTC GTGCTGTTGGTGTTGGTGTGATTA GTTGCATCATACAGAGAGATGAAG GGCGAACTCCGATGAGGCATTCA TTCTATTGGTCAGCAGAAAAACAA TATTATAGTGAGGAACCTTTACTA CGTCATTTGGAACCCCTCTATCTA TGTATCTCGAGCTGGACAAGCTTA AGGGTTATGAAGATATCAAATATA CTCCTTCCCGTGATCGTCAATGGC
ATCTTTACACGGTTATTGATAAAC Amaran- |cD- /638 GGCAGTTACTAATGTGACTGGTCA thus liviz- | NA- TACCTGTTCGGTACATGTTTATCG dus Con- TGAATTGGAAGATAGCAACCTACA tig TGAAATGGTCTACCATTCAGTATC
TGTTCACGGCCCCCACCATGGGG TACCTGTGAATGCACCCTACCAAC CACTCGGTGGCATCTCCCGTAAG CGACTTCAGGCCATGAAGAGTAG CACAACATACTGTTATGATTTTCC ACTGGCTTTCTCAACTGCCCTGAA GCAATCATGGGCATCGGAAGCTC CGGATGTCAAGAAACCCTCGGAC AAAGCACTTTTGAAAGTAACCGAG CTAGCATTTGCTGATCCAAAAGGC ACATGGGGAACTCCGCTTGTTCC AATAAATCGCAAGCCTGGTATGAA CGATGTTGGCATGGTAGCCTGGT ACTTGGAAATGTCCACCCCCGAG TTCCCTAACGGAAGAACAATAATG GTTGTAGCTAATGATGTTACCTTC AAGGCCGGATCTTTCGGACCACG AGAAGATGCTTTCTTCCTTGCTGT TACAAATCTTGCTTGCGCGAAGAA ACTTCCTCTTATTATCTGGCTGCC AATTCAGGAGCTCGACTTGGTGTT GCCGAAGAGCTAAAATCCTGCTTT
AAAGTTGGCTGGTCGGATGAGTC Amaran- |cD- |4689 CATAATACATTAAGTCCAGTATCT thus pal- | NA- ATACAAGAGATTAAACCAGCTACA meri Con- AAAAAGCTGATGAGCACAAGATAC tig ATCAAACAAAAACCAGCAGCTGAT
AGCAGTATTTCCTTTTTCTTAATGG CAAGAATGCTTGTCTGTGCTGGCA ACACGACTCCCCAAAGATCTGAG ATACGAATTGGAATCAAAATCTAG AGCTTTTGAAGCGATTACCAACAC CCCAAACATAGAATTTCCTGCTAA GTTGTTGAAAAGTATTCTTGAGGA CCATTTAAACTCATGCCAAGAGAA AGATAAAGGAGCTCAAGAGAGGC TTATTGAGCCTCTTATGGTTCTTG TAAAGTCTTACGAAGGTGGGCGA GAAAGTCATGCTCGTTTTATTGTT CAATCTTTATTTGAAGAGTATTTAT CCGTTGAAGAATTGTTTAGCGACA ATCTCCAGGCTGATGTGATTGAAC GTCTCCGCCTTCAGTATAAGAAGG ATCTGCTGAAGATTGTTGACATTG TACTGTCGCATCAGGGTGTTAAGA ATAAAAATAAGCTGATTCTACGAC TCATGGAACAGCTGGTTTACCCAA ATCCCGCTGCATACAGGGGGCAA CTTATCCGTTTCTCTCAATTGAAC CATACAATGTATTCTGAGTTGGCA CTAAAGGCCAGTCAATTGCTTGAA CAAACGAAATTGAGTGAGCTCCGT TCGAACATTGCTAGAAACCTCTCT GAGCTAGAAATGTTTACCGAGGAT GGCGAAAACATGGATACTCCAAAA AGAAAAAGTGCTATTAATGAACGT ATGGAGGCCCTTGTGAGTACTCC TCTAGCTGTTGAAGATGCCCTTGT CGGTTTGTTTGATCATAGTGATCA TACACTTCAGAGGCGGGTTGTTG AGACCTATGTTCGGAGGCTTTATC AGCCTTATCTTGTCAAGGGAAGTG TCAGGATGCTGTGGCACAGATCA GGTTTCATAGCTTTATGGGAATTT GTTGAGGAGAATATTGACCGAACA AATTTTTCNGATGATCTGACTACA AACAGTGGGAACCATAGTGAGCG AAAGTGGGGGGCCATGGTCGTTA TTAAAACTCTTCAGTTCTTGCCAT CGGTGATTGCTGCAGCATTGAGA GAAACAACTCATAGTTCCGATCAA TCAACTTCCACTGGCTCTATAGAA TCAGTCATCCATGGAAATATGCTG CACATTGCACTAGTGGGGGTGAA CAACCAGATGAGCTTGTTGCAGG ATAGTGGTGATGAAGATCAGGCT CAAGAGAGAATCGATAAATTGGCC AAAATTCTGAGAGAGCAAGAAGTG AGTTCAGCCCTTCGTGCTGCTEAG TGTTGGTGTGATTAGTTGCATCAT ACAGAGAGATGAAGGGCGAACTC CGATGAGGCATTCATTCTATTGGT CAGCAGAAAAACAATATTATAGTG AGGAGCCTTTACTACGTCATTTGG AACCCCCTCTATCTATGTATCOTCG AGCTGGACAAGCTTAAGGGTTAT GAAGATATCAAATATACTCCTTCC CGTGATCGTCAATGGCATCTTTAC ACGGTTATTGATAAACCATTCATT CGGAGGATGTTTTTGAGAACCCTT GTAAGACAACCCATCTCTGAGTTC ACAGGCGTCGAACTAAGCGCTCT TGAAACACAAAAGCCTATCTCTTT CACTTCAAGAAGCATCCTAAGGTC CTTAACAACCGCCATGGAGGAGT TGGAGCTCAATGCACATAGTGCTT CACTGAAACCCGATCACGCTCATA TGTACTTGTACATTGTCCGAGAGC AACAAATATACGATCTTGTGCCAT ATCACAGGGAGGTGAACATAGAT CACCAACAAGAAGAGGCTTCGGT TCAATTCTTTTTGGAAGATCTCGC GCATGAAATCCATAGTCTTGCTGG TGTAAGGATGCATAAACTAAATGT TTGTGAGTGGGAAGTGAAACTTC GGGTATCATCTCCCGGGAAAGCT AATGGTTTATGGAGGGTGGCAGT TACTAATGTGACTGGTCATACCTG TTCGGTACATGTTTATCGTGAATT GGAAGATAGCAACCTACATGAAAT GGTCTACCATTCAGTATCTGTTCA CGGCCCCCACCATGGGGTACCTG TGAATGCACCCTATCAACCACTCG GTGGCATCGCCCGTAAGCGACTT CAGGCCATGAAAAGTAGCACAAC TTACTGTTACGATTTTCCACTGGC TTTCTCAACTGCCCTGAAGCAATC ATGGGCATCGGAAGCTCCGGATG TCAAGAAACCCTCGGACAAAGCG CTTTTGAAAGTAACCGAGCTTAGC ATTTGCTGATCCAAAAGGCACATG GGGAACTCCGCTTGTTCCAATAAA TCGCAAGCCTGGTATGAACGATG TTGGCATGGTAGCCTGGTACATG GAAATGTCCACCCCCGAGTTCCC TAACGGAAGAACAATAATGGTTGT AGCTAATGATGTTACCTTCAAGGC CGGATCTTTCGGACCACGAGAAG ATGCTTTCTTCCTTGCTGTTACAA ATCTTGCTTGCGCGAAGAAACTTC CTCTTATTTATOCTGGCTGCCAATT CAGGAGCTCGACTTGGTGTTGCC GAAGAGCTAAAATCCTGCTTTAAA GTTGGCTGGTCGGATGAGTCAAA TCCCGAGAGTGGATTTCAGTATGT CTACTTAACCCCTGAAGATTACGA TCGTATAGGATCGTCAGTCATAGC CCACGAGTTAAAACTCGAAAGTG GAGAAAAAAGATGGGTTATAGATA CCGTTGTAGGTAAGGAGGACGGA TTAGGTGTTGAGAACCTATCGGGA AGTGGTGCTATAGCCAGTGCATA CTCAAGGGCTTACAAGGAAACATT TACTCTGACTTTTGTAACCGGAAG AACGGTCGGTATTGGTGCCTATCT TGCTCGTCTTGGGATGCGTTGTAT ACAGAGGCTTGACCAGCCTATAAT TCTCACGGGTTTTTCTGCTTTAAA TAAACTTCTCGGCCGGGAGGTTTA TAGTTCACACATGCAACTTGGTGG ACCGAAGATTATGGGCACAAACG GGGTAGTTCATCTTACAGTTTCCG ATGATCTTGAAGGCATTTCATCTA TCTTGAAGTGGCTGAGCTACGTTC CACCCTATTCAGGTGGTGAACTTC CGATTTCTCEGGTGTTTAGACCCTC CAGAAAGACCGGTTGCGTATTTG CCTGAAAATTCTTGTGATCCTCGT GGTGCTATATCTGGTACGGTTGAC TCCACCGGTAAATGGTTAGGGGGÇ TATTTTCGACAAAGATAGTTTTITGT GGAAACCTTAGAAGGATGGGCGC GAACAGTTGTCACGGGAAGGGCT AAGCTCGGAGGAATTCCAGTTGG CATAGTTGCCGTTGAGACGCAGA CTGTTATGCAAGTAATCCCAGCAG ATCCCGGTCAACTCGACTCACAC GAGAGAGTCGTACCACAAGCAGG GCAAGTATGGTTCCCAGATTCCG CATCCAAGACAGCACAAGCGCTG ATGGATTTCAACCGGGAAGAACTC CCACTTTTCATTTTAGCTAATTGGA GAGGTTTCTCGGGTGGACAAAGG GATCTCTTTGAAGGGATCCTTCAG GCCGGATCCACCATAGTTGAAAAT CTTAGGACTTATAATCAACCCGTT TTTGTTTATATCCCTATGATGGGG GAGCTTCGAGGAGGCGCATGGGT GGTCGTCGATAGTCGAATTAATTC CGACCATATAGAAATGTACGCCGA CCAAACAGCTAAAGGAAATGTGCT TGAACCGGAAGGAATGATCGAGA TTAAGTTCCGAACCAAGGAACTTC TCGAGTGTATGGGAAGGCTTGAT CAACAACTCATCGGTCTCAAGGAA AAACTAGCCGAAGCCAAGAGCTC TAATTCCTACAATAAAATCGAGCC CCTGCAGCAACAAATAAAAGCCC GCGAGAAGCAACTATTGCCTCTAT ATACTCAAATAGCCACCAAATTTG CCGAGTTGCACGATACGTCTTTAA GGATGGCTGCCAAAGGAGTTATT AGGGACGTCTTGGAATGGAAAAG CTCGCGTTCGTTCTTTTACAAAAG ATTATACAGGAGAGTTATGGAGGA ATCACTCGTCAAGACTGTTCGAGA TGCTGCAGGTGAACGGTTGACCC ATAAGTCGGCTTTGGAGTTGATCC AAAAATGGTTCAATGAGTCGAATA TCTCCGGAGAGGCTTCCGATGCT TGGGCTGATGATGCGGCCTTCTTT AAGTGGAAGGACGATACCGCCAA CTACGAGGAGAAGTTGAAAGAGT TGCGCGTTCAGAAGGTATTGGAT CAGCTGTCGAATATTGGAGATTCG GCAACTAATTTGAGGGCTCTGCCT CAGGGTCTTGCTGCCCTACTTCAA AAGGTGGATCCATCGAGTCGAGA AGAACTAGTCGAGGAACTCCGTA GAGTGCTCACTTGATTTCGCAACC GTTGATGGTGAAGTGAAACCTTCT TGGTTTCATCATGGTAGAAAATAT TATTAGGCAAATCTATAATTCTAGT TACATCCATTGTTTTAGACAATAGT ATTGAACTAATTTATTTAATTAAAT TGTATAAATAGGAGACCTTGAATT CATTTGAATTAAGTGGCTTATGCT TGCATTATTTTGTATTGAATCAAAT AATTATTTACATACTTTTGATTATT AATAATGGTAAATCCTCAAA-
ATTTGAGGGATTTGTTACCT 1 Amaran- |cD- |/1582 GTTGCAGCATTGCATAGCCGTGAT thus pal- | NA- TGCAGTGTCCAAAGGCGGCACCA meri Con- AAAGATCATTGAAGAAGGCCCAAT tig AACGATAGCTCCACCAGAAACGG
TGAAGAAGCTTGAGCAAGCAGCT AGAAGATTGGCTTTATGTGTGGGT TATGTTGGCGCAGCTACAGTTGAA TATTTATACAGCATGGAAACAGGC GAGTTCCATTTCCTTGAGTTGAAT CCTCGGTTACAGGTGGAGCATCC TGTTACTGAGTGGATTGCTGAGGT AAATCTTCCAGCTGCTCAAGTTGC AGTTGGCATGGGTATCCCACTTTG GCAAATTCCTGAAATCCGTCGGTT CTATGGGAAGGAACATGGTGGGG GTTATGATACTTGGATGAGGACAT CTGCTTTGGCTACTGCTTTTGATT TTAACGAGGCACAGTCGGTGAAA CCTAAAGGTCATTGTATTGCTGCG CGTGTGACAAGTGAGGATCCCGA TGACGGTTTTAAGCCTACAAGCG GGAAAGTACAGGAGCTGAGTTTTA AAAGTAAACCGAATGTGTGGGCC TACTTCTCTGTTAAGTCTGGGGGA GGCATTCATGAGTTCTCGGATTCT CAATTTGGCCATGTTTTTGCATTT GGTGAAAACCGAGGTTTGGCCAT AGCAAATATGATTCTTGGATTAAA AGAAATTCAAATTCGTGGAGAAAT TCGAACTAATGTTGATTACACCAT CGATCTTTTAAATTGTTTGGATTAT AGAGAAAACCAAATTCATACAGGT TGGTTGGATAGTAGAATTGCGATG AGGGTCAGAGCTGAAAGGCCACC TTGGTACATCTCTGTTGTGGGAGG AGGGCTTTACAAAGCATCGACTAG TAGTGCAGCGACTGTTTCAGAGTA TATAGGCTATCTTGAAAAAGGTCA AATTCCTCCGAAGCATATATCACT CGTCCACTATGAAGTTGCTCTAAA TATCGAGGGGATGAAATATACCAT TGAGATGATTAGGGGTGGACCAG GAAGCTACAAAATGTGGTTGAATG GGTCCGTAGTTGAGGCGGAAATA CATACTTTAAGAGATGGGGGTCTC TTGATGCAGTTGGACGGAAACAG CCATGTGATATATGCCGAGGAAG AAGCTGCAGGAACTCGCCTTCTG ATTGATGGAAGAACTTGTTTGCTT CAGAACGATCACGATCCTTCAAAG CTAATTGCGGAGACTCCGTGTAA GCTTATGCGGTATTTGGTACCAGA TAACAGTCACATAGATGCAGATAC TCCGTATGCTGAAGTTGAGGTCAT GAAGATGTGTATGCCTTTGCTITTC CCCTGCATCCGGTGTTTTACAATT TAAGATGTCCGAAGGTCAAGCTAT GCAGGCTGGTGAACTCATAGCTA GTCTAGAGTTGGATGATCCTTCAG CTGTAAGAAAAGCCGAACCTTTCA GTGGAAGCTTTCCTGTCATGGGC TCACCAACTGCAATATCTGGAAAA GTTCATCAGAGGTGTGCCGCAAG TTTAAATGCCGCTCGGATGATTTT GGCTGGTTATGAACACAATATAGA TGAAGTAGTACAGAGTTTGCTG-
GAATGCCTTGATAGTCCCG 12 Amaran- |cD- 822 AGATGTGTATAAGAGACAGTATAA thus pal- | NA- TCAAGTTTTTTAGTACCCAAAGCT meri Con- CTAAATGTTACTTAAAGTTTTGATC tig TTTTAATGGTTTCTTCTATTTAATC
CAATAATTTAAAGTACCCAGATTT CAATTTTTAGAATAAATTGAGTTTT TGAATTGCCCAAGTTGTAATTGTT GCTGAATTCTCTTGCTTTGATTTG GGTTTTCTGATTCTATCCCTTCTG ATTCATACAGTTTCAGGAGCAGTG GTCTCATTTTCEGAGCAATACAAAA AGTGCCGTGCTTCTCTAAACAACG ACGATTCAGACATGTCTTCTCCTT CCCACAATAATGAAAACCCGAACG GACCGATGATGCCACTCCTGAGG AATTCATCTGTAGTATCCATTGTT GATAAGTTCTGTTATGCTCTTGGA GGGACGCGGCCAATCCATAGTAT TTTGATAGCAAACAATGGGATGGC TGCTGTCAAATTTATAAGAAGTAT CCGAACATGGGCTTACGAGACTTT TGGTACTGAGAAGGCTATATTATT GGTAGCCATGGCTACTCCCGAAG ACATGAAAATCAATGCCGAGCATA TTCGAATGGCTGATCAGTTTGTTG AAGTCCCCGGAGGAACTAACAAC AATAACTACGCCAATGTGCAGCTC ATTGTTGAGTTAGCGGAAGTTACA CGAGTTGACGCAGTTTGGCCTGG TTGGGGACATGCATCGGAGATCC CCGAGTTGCCAGATTCATTAGCTA CGAAGGGAATTGTGTTTCTGGGC CCCCCAGCTGCATCTATGGCTGC TCTTGGAGATAAAATTGGTTCAT-
CATTGATTGCAC 13 Amaran- |gD- |17981 | AMACCAAACCAACCTCCTTAAACT thus pal- | NA- TCTCTTCTTCTACTCACCATTTITTT meri Con- CCTCTTTTITATTGATTATTGATTITT tig AAATATACATTATATTGTAGGAATT
TAATGAAATTTTCATTAAATTCTGA TAAAGTTTTGATTTTTTTTAGTGTA TGAGATTTTTCAGAAGTACCCAAA TGGTAAATTTCAAGTATAATCAAG TTTTTTAGTACCCAAAGCTCTAAAT GTTACTTAAAGTTTTGATCTTTTAA TGGTTTCTTGTATTTAATCCAATAA TTTAAAGTACCCAGATTTCAATTTT TAGAATAAATTGAGTTTTTGAATTG CCCAAGTTGTAATTGTTGCTGAAT TCTCTTGCTTTGATTTGGGTTTTCOT GATTCTATCCCTTCTGATTCATAC AGGTATTCTGATTTTTTCTTGCTTG ATTACTTTTTGTTAGTGTATGGTTG AGCTAATTTAGTTTATAGTAGTGT GAATTTTATTTTATTTTTITTCAATT TTTTCAATTATTTCAATTTGTAGAG TAGATTCTCCTATTATGATTTGTTT TTGTAGCTGGGTTTTAATTTITTATT GTCTGATGATTTATCTTAGCAATG TTTTAATGGGTGTGCTGTTTTTCA ATTTATAGTGTAATTTAGTTGATTC CTCTTTTCCAATAGAGTGTACAAA ACCGACCTGATTAACTGAAACCGA GTATTATCCAACGGGAACAATCCC TGTTACAAAATTCAAATTAGAATGT CAAGTACCGAAATCAACCCGACC CCACATATTATACCCGAGATCCAC CCGAACACCCGAATGAACACCTC TGAGATCATAGAGAGGATATAAAG AAAAGTGGAACTAGAATGGGGAA TTTAGTTTATTTGAGCTACATTGAG CAAAATTTTTTTTAGTGACTGATTA TTGTAGCTGGCTTTTGTTGTATAA CTCATCTAAGCAATGTTTTTGATG TGTGTGCAGTAGCATTGGATTGTT TTGATTTTTTGTTATATTGTCTATA CAATTCAAATCTTGAATCACACTT GACTTTTAGTTCCATTTTCATCTTC ACAAATTCTTGTGAGAGACTGTCA ACTGTGAGACGCTCTCTGTACATG GGCTAAATAGCGTAACTAATACAA CTATTAGCATATGAGCTTCTTATTT TGAGGTCGTCTCTCATAAGAGTAG CTCTCTGTTCTTTTATGATTTATGA TTCAATGCAAATAAATTATTTACGG CCCGTGTGGTAGEGTGGTAATAAA CAATAGTAATGAGAATGAAAAACA AGTGTAATTTTGGTTAAAAAATCTC TTGGTTACGTTGATGGTCATGCTT GTCCAACTTAAATCATCTCACACT ATCATTGGGAGAGGTGGTGTTAG GTGGTAATGAAAATTTGTAAACAA AAAAACTTGTTTGTGATCAAAGTTT CATTACCATAGGAACGATACGGAA CTTTTGATGAAATTTTACACTATAA ATCATTTCCATTACCACCATTTAGT ACCTCTAACCAAACGGGACGTTA GAGTTTTGCTTACCTACAATATCTT CTTAGCTCATAAGCTCAGAACCTT ACTTCAATTTTGACCATATGTTITTCT AGCTATACTTTCAGTAAGTATTTAA AAATTCATTTTCATTTTATCTATGT ATAGTTGCGAATGATGTTTGTTAT AAAGGGTCAATCGAAAAACTTCCT CTTTGTTATTAGTAACAAGGGTAA GGTTATGTACATCCAATCCCTCCA AACCCTTTTTGGGTGGGAGCTACT AATGGCGCTGGGACAATGGAGTT GTTGTTTGTCGAATTCAAGCGGG GAAGTTTGTTTAGAATGAATGTTA TTTCTAAAAATAGATGGTATAAGTA TGTTAATCAACAATTAATAATAGAG AACTGTTTTATTGGTGTGATAAAC AGTTTCAGGAGCAGTGGTCTCATT TTCGAGCAATACAAAAAGTGCCGT GCTTCTCTAAACAACGACGATTCA GACATGACTTCTCCTTCCCACAAT AATGAAAACCCGAACGGACCGAT GATGCCACTCCTGAGGAATTCATC TGTAGTATCCATTGTTGATAAGTT CTGTTATGCTCTTGGAGGGACGC GGCCAATCCATAGTATTTTGATAG CAAACAATGGGATGGCTGCTGTC AAATTTATAAGAAGTATCCGAACA TGGGCTTACGAGACTTTTGGTACT GAGAAGGCTATATTATTGGTAGCC ATGGCTACTCCCGAAGACATGAAA ATCAATGCCGAGCATATTCGAATG GCTGATCAGTTTGTTGAAGTCCCC GGAGGAACTAACAATAATAACTAC GCCAATGTGCAGCTCATTGTTGAG GTAATGTATCGTGAGATTAGAAAT TTCTAGCCTGTAATCCATAGTTAC ATGGAATGTGGAACATAGCCACG TTCCGCGATTCGGGAACATTCAAT CCCAATCACCATGAAACCCGACCT AAATCACTAAAGGTGACGTCCCG GTGTAGAACACCTTTTTTTTAAAAT GTATTTTTGGCCTTCATTTACAAAT TAAAGGAAAAAGAAAGGAGGAAA AAACAAGATGTAACCCAGAAACCT AAACAAATCCACTTGAAAATAATTT CTTAAAGCAAATTAATCATTTTAGT TTAATTTTGTTTCAAATATATATATT ATACATAATGTGTCTCATACCCAA TCGTTCTTGAGTAAATCTAGGTTG CGTTCTGTGTTCCCATTCOTTGTTT CCCGTTCGAAACCAAATGTCGTTC AGTTAACAATGCTGTTATCTGCTT TACTGTGATTTATTAAATGTGTCCT TTGAAAAAAAGGCAATATCAGAGC GACTCGACGCAGTTTGGCCTGGC CGGGGACATGCGTAATATGTAATA TGAGATTACAAATTTATAACCTTITT ATATGGTAAAATCTTGTGGTAGGA CTAACTTAAATCCTTTITTCTTTCAG TTAGCGGAAGTTACACGAGTTGAC GCAGTTTGGCCTGGTTGGGGACA TGCATCGGAGATCCCCGAGCTGC CAGATTCATTAGCTACGAAGGGAA TTGTGTTTCTGGGGCCCCCAGCT GCATCTATGGCTGCTCTTGGAGAT AAAATTGGTTCATCATTGATTGCA CAAGCTGCAGATGTCCCAACTCTT CCATGGAGTGGTTCTCATGTACGT ACTACACGTTTTITITITTOTITIIITT TTTCCTTCCAAATTTCTGATCTTTA GAGTTTTAGTGATAGATTTATATAC GTCTCTATCCCTCAGGTGAAAATT CCTGCTGAGAGTTGCCTAGACGT AATTCCCGATGAAGTATATAAAGC GGCATGTGTTTTTACTACAGAGGA AGCAATTGCTAGCTGTCAAGTTGT TGGTTATCCGGCTATGATCAAAGC TTCTTGGGGTGGTGGAGGGAAGG GAATAAGAAAGGTAAAATTTITTT GGATGATGATGCTCTTAAAAGACT AAAAGGAGGTTACACATATCCCCA TTACTTGTTTATCATCAGAAGCAG AGCAAAAATTGACAAAGATTTAAA GACTCTGTGCAATTTCAAAAATAT GATATATTTCTAACAACGTATCTTC AAACACTTTAAACATACTACCTATT TTAATACTGCGGCCCCTATTTITITT GAGGCCGTGTGTGGTCGAACATA TTGAATATGCTTAGAACCACTCCT GTTTATCACTAATATGCCATCTTC CACAGTCGAACCTCTACTTTGACC CAGATTCCTTGAAAGGGATTTCGA TTTAGACTCGAGCTATGGTCAATT ATTAGCAATAGCAAAAGCTTCTTA ATAGTTAATAGATTCTCAAACACTT CCGTCATGCCAACACTTTATGAAG ACTCATGGGTATTCTCTCTTTTAG GTTCATAATGATGACGAAGTACGG GCATTATTTAAGCAAGTGCAGGGT GAAGTTCCCGGCTCACCCATATTT ATAATGAAGGTGGCTTCACAGGTT AGACTTTCTTCAACATTGGTCCGA TATTCGAGTAAATTGCATTAAAAAA GGTTAAATATACAATTTTTITTGGAT AAGTATTGTATGAGAGACTACTAC TAAGATAAAGTATTATTAATATGTG CAGAGTCGACACTTAGAAGTACA GTTACTGTGTGATGAATATGGCAA TGTTGCAGCATTGCATAGCCGTGA TTGCAGTGTCCAAAGGCGGCACC AAAAGGTGGGTCTTTGGTAGATTA TGGTTATGATCTACGGTTTGTTAT TGTTTAAGAAAAATATTTGATTTTA AGCATTATTTAGCTTGCTGGGATT TGAACTTTTCTGTTCATCATTTTAA CTAATCAGATCATTGAAGAAGGCC CAATAACAATAGCTCCACCAGAAA CGGTGAAGAAGCTTGAGCAAGCA GCTAGAAGATTGGCTTTATGTGTG GGTTATGTTGGCGCAGCTACAGTT GAATATTTATACAGCATGGAAACA GGCGAGTTCCATTTCCTTGAGTTG AATCCTCGGTTACAGGTATGGAG CTTCCCCAACTTCTTTTAAGTACC CATTATGTAACTGCATATTTATGTA ATCCCTCCATTCCAAATTAGTCOGC TATGTATTCCTATGGGGATGTCCC AAATTAGTTGCAACATTTCTGTATA TGGTAAAGTTTTCCCCTCCAAACC TTAAAACCTAGTTGACCATAATCT AACTAAACCCAATTCTTGACCCAC TTTGAAAAACAGGTCAAATGTTGG TGTTTGAACCACCTTTAAACAAATT TAAGATTTTGGGTTGGTAATGGCT TATCAGAGATTTGGGTTTTTGGCA TCGGCATTATTTTGGTGTCGATTT GCAAATGATATCCCGGGATTTCGA ACTAGGAGGGGATTCAATTGGTTT TTGAGGAATTTATGTAATTATTCCT TTAATTAGTGATCATTGAATTGATT GTATTTGTGTTGGGGAATTGGACC CGTGAAGAAAAAAATGACGGGTTA GCTTTTGGATTAGTGAGTGATTAT GTGAGTTTAATTTGTCTATGAAAG GTCAACTTCAAGCAACATTTTCTG TTTTAGCTTAGTAATTTTTGGGATG CGATGGAACATTTGAGCACCTTCT GGATTATCAACAGAAATGATCATC GAAATTGATTTTTTTAGTTGTTGAC AGTAGAAAAGTATCAGATAAGGTA GAATAATACAGTATAATCTTTAGTT GCGACAATTTCCAACGTTTTTATA ATAGCTAAAGCTACATTCTCATGT TGCTTGATGAAAGTGACCGTATTT ATTCTGTGTGCTTATACAGGTGGA GCATCCTGTTACTGAGTGGATTGC CGAGGTAAATCTTCCAGCTGCTCA AGTTGCAGTTGGCATGGGTATCC CACTTTGGCAAATTCCTGGTAAAT GTCCAGTACTCTTTTTTCGGTTAT GTAACTTATATATTATATCTAATTC TTATTTACGAACCGAATTGATCAC ACATTTTTAAAACAGAAATCCGTC GGTTCTATGGGAAGGAACATGGT GGGGGTTATGATACTTGGATGAG GACATCTGCTTTGGCTACTGCTTT TGATTTTAACGAGGCACAGTCGGT GAAACCTAAAGGTCATTGTATTGC TGCGCGTGTGACAAGTGAGGATC CCGATGACGGTTTTAAGCCTACAA GCGGGAAAGTACAGGTTAGACCA TCCTGGTTTTGTCGATTTACTTCC ACAATTGGTCTTGTTTTGTTTTTGC CTTTGCGGTGAAGAATTTTCTITTA ATGGGTGCTTTGTTTAGGAGCTGA GTTTTAAAAGTAAACCGAATGTGT GGGCCTACTTCTCTGTTAAGGTAT TTTCCATATTTCTTTAATTCTTTGA TTTTCGCGTTTACAATTTCAGTTCA CTCCATTATGGGCTTGATGATGAT AAACACTTTTATTTGCAGTCTGGG GGAGGCATTCATGAGTTCTCGGA TTCTCAATTTGGTAAGTTAATGGT GCAAACTCTTGTCAGTAATGTTAA CTACAGTTTCACATGATTTACTAAT CTCTTCGTGAATTGCGAACTAAAA AAGAGAATTATTGTCAGTTTTGGG CTATTTTTTATTCCATTTTGAGCCA ATGGAAATTCAAAAAGCGAATAGC TAGCGAATTTTGTTGATATTCTGG AGGTGTATATTGATGAGAATTTTA CAAAAAGTTGCTGCTGCTGCACTG TGTTATTTTTTAGAAACACTGGGT GACTTTCAATTGTTTGTAAAACTTG CATATTCGAGTCACAACATGATGT CATAATGAAATGCGAGCGGTTTTITT ATTAAATAATAGAGCCATAGTGTA ATCGACCAATATTTAGGTGGTGCA ATGACCGCATCACTCCCGTTACC GCATTACCGTTCCCTACCGCGATC ACGATCGTTAGCGCATTTTTACGC TATGAATAGACCTTCAGTTCATATT TTATGATGGCTAAAATCAATCACT TGGTTAATGGTATATCATATACGA AGGCTAACAAAAGAATTTCTITTAC AGGCCATGTTTTTGCATTTGGTGA AAACCGAGGTTTGGCCATAGCAA ATATGATTCTTGGATTAAAAGAAAT TCAAATTCGTGGAGAAATTCGAAC TAATGTTGATTACACCATCGATCT TTTAAATGTGAGTTTGAATGTAATT TTTGTTGTCTTTTTTTAGTTTTCGC CTTTCTTCTGTTAAACCTTTGAAGT TCTCACACTTAACTTTITTTITCCTC CAGTGTTTGGATTATAGAGAAAAC CAAATTCATACAGGTTGGTTGGAT AGTAGAATTGCGATGAGGGTTAG AGCCGAAAGGCCACCTTGGTACA TCTCTGTTGTGGGAGGAGGGCTT TACGTATGTACAACTTTTTCATAG CTATCATTAATTTTTCCGTTGTTAT GATCTGTGTTACTTGGACTCGGGT TGTTGGATACTGGTATGTGTCCAC GTGTCGGATACGTCTAAATATTCA ATTTTACGCCTAAAATGAAGTATC TAAGTGCCATGTCCGAGCATCAA GAATCGGACACGGGTACGTGAAG CCAAATGAAGAGTCCGAGTAACAT AAGTTATGATTAATGTTAAATAACT TGTTTTCTTTATCCTCTATATCCAG AAAGCATCGACTAGTAGTGCAGC GACTGTTTCAGAGTATATAGGCTA TCTTGAAAAAGGTCAAATTCCTCC GAAGGTATGTAACATACAATTGGT TGGCGGGTGTTTAGATTAACTTAT TCTATTAATATCAATTATACTTTCA GTGTTCTGCTTTAATTCTGGTTTC ATGATTGCAGCATATATCACTCGT CCACTATGAAGTTGCTCTAAATAT CGAGGGGATGAAATATACCGTAT GTTCCATGCCATTCGTACTTTCCOT CGTGAATTTTTGTTATGGATGCTA TTTTTGACATTTTCTTTCTAAATAT ATTTTCTTGAAATTAATGAACATGT CGTTTCGGATTGCCAGATTGAGAT GATTAGGGGTGGACCAGGAAGCT ACAAAATGTGGTTGAATGGGTCC GTAGTTGAGGCGGAAATACATACT TTAAGAGATGGGGGTCTCTTGATG CAGGTATCAAATGTTTTTTGATATT TTTTTTTCTGATATACGGTATTTAT ATTTTATATCCAAAGCATGGTGAT AATACCCTGGATTTGTAAAGCATT AGATAATATGTTATCAAACAAGTA GAAGGTAGTTTCGTGAAACCATGA AGCGTTTAGTTTAGATTTGAATTTT AATACTTCTACAATGCTTGGGATA TTAATCAATAATCATGCTTCTAATA GTAAAGAGAAATATTGTCATAGAC TCATAGGTATAATGGCTCGTTAAA TCATATGCACTTCTTGTTTATGTGA AGTCCGAGTTGGTGTTTGCAATCA ACGTTTGAAATCAAGGGCATAGTG CAAAATCTCGAATGTGGTCACTTT TGTGGTCAATGTAGATGGTTTCAT TTCTATCGTGGTATAAATATGGGT CGCAGTAATCTTAAGAACCTATAT AGTAGACGATAACTTGTTATTAAA AGGGTAAAGGCTGCATACATCCG ATGTCCCATTTACCCGGTCTAGAT GTGAGCTACTTGGGGTTTTTGTTA TTGAAGTTAAAGATACAAGAAGGA TTATTGCTAAAAAAAAAAAAGAATA TTTGAACTACAAAAAAAGTAATTA GTTTATGTACTAGTTCGTTCTAGC CCATATAACTCATTTAAAAAAATAT ATGAAAAAGGGCTTTCAATGTCAT GAACGGAAGGGAGGAAATGGACT GTGGAAGAGTCAACAAAGATTACA TATGAATTCTCTTTTGTTGTTTAAA AAACTTTGAAATTGAAAATTGTTG GCTTTTTGTTGAAGAAACGATGTG TGTCAGTTGAAAACAGAATATTTA AACTACAAAAAAAGCAATTAGTAT ATACACAATACACTTGTTCATTTAA ACCCATATAGTACATTTAAATAATT ATTTGAAAAGGGCTGTTAATGTGT GAAGACTTTCGCTATATTGATCTG ATTGGATATGTGTAATACCTTGAA ACGTCATGCAGTTGGACGGAAAC AGCCATGTGATATATGCCGAGGA AGAAGCTGCAGGAACTCGCCTTC TGATTGATGGAAGAACTTGTTTGC TTCAGGTAATGCCGTGTGATTCTC TITTITITIIIITITITGTGAATTCTA AACCTTAAAAATCATTCTTCACCG GACATGTTCATTTTTCCATATAGAA CGATCACGATCCTTCAAAGCTGAT TGCGGAGACTCCGTGTAAGCTTAT GCGGTATTTGGTACCAGATAACAG TCACATAGATGCAGATACTCCGTA TGCTGAAGTTGAGGTCATGAAGAT GTGTATGCCTTTGCTTTCCCCAGC ATCCGGTGTTTTACAATTTAAGAT GTCCGAAGGTCAAGCTATGCAGG TATGCATCATTTTAATCGTAAATTC AGCAACCTCGTTTATATTGGATTC TATATATGGTCTTGCTGTGTAGGC TGGTGAACTCATAGCTAGTCTAGA GTTGGATGATCCTTCAGCTGTAAG AAAAGCCGAACCTTTCAGTGGAA GCTTTCCTGCCATGGGCTCTCCAA CTGCAATATCTGGAAAAGTTCATC AGAGGTGTGCCGCAAGTTTAAAT GCCGCTCGGATGATTTTGGCTGG TTATGAACACAATATAGATGAAGT AAGTTTCAAACCACCATTTCATTTT TCATCAACATAGTTTTTAGGCTAG CCTCTTAATGGGTTGATGCCATAG TGTAAAAACAAGGCCACATCGCAT CACGTCACCGCGTTGTTAAGGATT TCAAAAACAACGAACCGATATTTC CCATGTTGTGGGCCGTACCAAGG GATATCTTATGGTTTTGACCGGTA TTTAGGCGTTACAATAACCGCATC ACTCCCGTTACCGCATCATTGTTC TGTTACACTATGGATGCCGAACCT TGAGATGCATTTCCCATTTTTCAAT AGAGCCCCTAGTTTITITCOTITCCOT GTTTGGAAATTTTTTACATGTGAG CCTTTTATTTTCTCAGGTAGTACA GAGTTTGCTGGAATGCCTTGATAG TCCCGAACTTCCATTCCTTCAATG GCAAGAATGCTTGTCTGTGCTGG CAACACGACTCCCCAAAGATCTGA GATACGAAGTGTGTATTCTATCAT CTGTTCTTTATTTAGTTATTTATAT TTCCTTATAATAATTTTGAACTTTT TCCTCGGAGTTTACAGTTGGAATC AAAATCTAGAGCTTTTGAAGCGAT TACCAACACCCCAAACGTAGAATT TCCTGCTAAGTTGTTGAAAAGTAT TCTTGAGGTTAGTACCTCACTTTG TTACCTTCTGTAAATTATTCATTCG GCGAGTTACTCATGTTAGTAACAT GTTTATTCTTCGTAGGACCATTTA AACTCATGCCAAGAGAAAGATAAA GGAGCTCAAGAGAGGCTTATTGA GCCTCTTATGGTTCTTGTAAAGTC TTACGAAGGTGGGAGAGAAAGTC ATGCTCGTTTTATTGTTCAATCOTTT ATTTGAAGAGTATTTGTCCGTTGA AGAATTGTTTAGCGACAATCTCCA GGTTTGTCCATCTATCTAGAGCAA TTTGATTATGATGTTTTTTTAAAGT TCATAAATTTTAGCTTGGTGCCAC ACCGTCAGTGGCTGATGATCGTC GCTTTGTGATCATTAAGCTTTTAAA AGCTGTCTCCTGTTCTCCATCACT ATTTTTAGAAATTTTGAGTTCTGAT GTATATACTCGGTACCCGAGGGA CTCTTTGGCCGCTTTCTTCTITAT GGGTATGAGTTGCCTCCTTCCTTC CCTCCCCAGATCCTGATCATAGTT TCTATGAGCGGGATACATTGGGTA TGATGATGATGATGTATATACTCG GTGCTGAGCCAGCATATGAAAAG CAAACTGTCGTGAATTTATCTTAT GTCTTTAAAGAATACCGAGGCACC TGATTTTACATTTTATCTITATITIT TTCTGTATGAAGAAATAGTAAATTA TATTCTTCAATAGTTGACTCGGAG TGATGTTTGTAATATGTTTAGAAAA AATGTTGGACTAGAAAGTCAGCG CAGCGCATATATTAGTTTATGATT GTGGCTTTAATCAGTTTATGCTTTT GATGTTAATCTTTCCAGGCTGATG TGATTGAACGTCTCCGCCTTCAGT ATAAGAAGGATCTGCTGAAGATTG TTGACATTGTACTGTCGCATCAGG TACGTATTCTTGATTTACTGTTGTT CCTTTTGTTCTCTTCGGCATTTCTA TTTTTTTTTAATATATTTTATGGTTT TCAGGGTGTTAAGAATAAAAATAA GCTGATTCTACGACTCATGGAACA GCTGGTTTACCCAAATCCCGCTG CATACAGGGGGCAACTTATCCGTT TCTCTCAATTGAACCATACAATGT ATTCTGAGGTTGGTGATCCTCAAA CACCCAAAGCTATGTATTTCTCAT AATGCTTAAGTAGAGTAATAATTA ATAATTGTCCAATGATTGCAGTTG GCACTAAAGGCCAGTCAATTGCTT GAACAAACGAAATTGAGTGAGCTC CGTTCGAACATTGCTAGAAACCTC TCTGAGCTAGAAATGTTTACCGAG GATGGTGAAAACATGGATACTCCA AAAAGAAAAAGTGCTATTAATGAA CGTATGGAGGCCCTTGTGAGTAC TCCTCTAGCTGTTGAAGATGCCCT TGTTGGTTTGTTTGATCATAGTGA TCATACACTTCAGAGGCGGGTTGT TGAGACCTATGTTCGGAGGCTTTA TCAGGTGAATACATACTTTAAATG CGGACTCGGTCCTATTCATTGTAG AAACTTCTCTTGATCTTTCTCGAG TCGGGGGACTCTTTGGCCGCACT CTCCTTTATGGGTATGAGTTGCCG CCTTCCTTCCCTCCCCAGACCOCTG CACATAGTTTTTCTATGGGAAGGA TACTCTGGGTATGATGATGATGAT TATTATTATCGCTACTTGAACAATT TTTCTTATGTTATTTAACTCCTTTT TTGTTTTTGGCAACCGCTTTCTCA GCCTTATCTTGTCAAGGGAAGTGT CAGGATGCTGTGGCACAGATCAG GTTTCATAGCTTTATGGGAATTTG TTGAGGAGAATATTGACCGAACAA ATTTTTCTGATGATCTGACTACAAA CAGTGGGAACCATAGTGAGCGAA AGTGGGGGGCCATGGTCGTTATT AAAACTCTTCAGTTCTTGCCATCG GTGATTGCTGCAGCATTGAGAGA AACAACTCATAGTTCCGATCAATC AACTTCCACTGGCTCTATAGAATC AGTCATCCATGGAAATATGCTGCA CATTGCACTAGTGGGGGTGAACA ACCAGATGAGCTTGTTGCAGGATA GGTAAATAAGACTAGCCTGTAACA TATGGTGTAATAATCTTTATTATGT AACCTTGTGCTTCTAATGTCCTTITT AGTTCTATGGACTATATTAAAGTA CACTTCTTGTTCATGTGATGTTGA TGTTGATAATTGCTATCGGGTCAA TCACAAACAACCTCTTTGTTATCA CTTGAGGTGTTCAAAATAGACCCG ATGACTCGATATTCATCAGATCTT GTAACTGAACTCGACTTCAAAATG AATTTAAAATTATATAAAAATCAAT ATGGACACAAGACCGGATATCAAT CCGACCCGAAATAGTTGACTCGA AATCAACTTGATGATCCGAATGAA CACCTCTAGTTATCACTAACAAGG GTCAGATTGCGTACATCAAACCCC TCAAATCCTGCTTAGGTGGGAGCT TGTCAATGGCTTAGGGGTAACGG GAATGTGTGTGCTATGTACATTGT GCATCTATTCTTATACTTATGTTGA GTTTTTTGGATCAAATATAAAGAA CTTAACTTTTGTATTTTCTTGATGT GGTGTAGTGGTGATGAAGATCAG GCTCAAGAGAGAATCCATAAATTG GCCAAAATTCTGAGAGAGCAAGA AGTGAGTTCAGCCCTTCGTGCTG CTGGTGTTGGTGTGATTAGTTGCA TCATACAGAGAGATGAAGGGCGA ACTCCGATGAGGCATTCATTCTAT TGGTCAGCAGAAAAACAATATTAT AGTGAGGAGCCTTTACTACGTCAT TTGGAACCCCCTCTATCTATGTAT CTCGAGCTGGTACTAGTCTCTGAA CCGATTGCCTTTCTTCTGCTTTGT TATTCTGTGTGATATTTCGACTTAA GTCTAATTTACATCGTTTTGTACAT TTGTTATCCAAAGCACGTTAAAAG ATACTTCCTTCGTTTTTTTACAAGC ACCCAAACACCTTTTTACGCAGCC CAATTGGTTTGTCGGGTTGCTTAT ATATAGAATTATACTCAACTTAAAA ATTATAAAATTTGATATTATGAAAG TATTCGACGTGACGAATTAAACAA AATCCCATATGACTATGTTITTITTC TCGTTTAATAGCTGTAATATGTAAA ATACTATCGAATGATGAATAGTGT AAAAACTGGTTTGGGTGCAACTAA AAAAATGGAGGAAGTATAATTATG CAGCCAAAATTGATGGCTTTTAAC TTTTCATCAAATCAGGACAAGCTT AAGGGTTATGAAGATATCAAATAT ACTCCTTCCCGTGATCGTCAATGG CATCTTTACACAGTTATTGATAAAC CATTCATTCGGAGGATGTTTTTGA GAACCCTTGTAAGACAACCCATCT CTGAGTTCACAGGCGTCGAACTA AGCGCTCTTGAAACACAAAAGCCT ATCTCTTTTACTTCAAGAAGCATC CTAAGGTCCTTAACAACCGCCATG GAGGAGTTGGAGCTCAATGCACA TAGTGCTTCACTGAAACCCGATCA CGCTCATATGTACTTGTACATTGT TCGAGAGCAACAAATATACGATCT TGTGCCATATCACAGGTATCTATT GCTGCGTGCCTCATTTITITITIT GTTTATTATTGGTCATTAGTACAC CTTATTCTTAGAAGAAACTTTTITTTC GGCCAATTATTTCCAGGGAGGTG AACATAGATCACCAACAAGAAGAG GCTTCGGTTCAATTCTTTTTGGAA GATCTCGCGCATGAAATCCATAGT CTTGCTGGTGTAAGGATGCATAAA CTAAATGTTTGTGAGTGGGAAGTG AAACTTCGGGTATCTTCTCCCGGG AAAGCTAATGGTTTATGGAGGGTG GCAGTTACTAATGTGACTGGTCAT ACCTGTTCGGTACATGTAAGTCAT AAGTTTGAGAACCTCTTTITTTGAT CTAGTCACAATTTTGATTTTTCACA AATTCTTGTATGAGACGGTCTCAC CGTGAGAATCACCCCATACTTGGA TTAAATAGCCGAATAATAGAAACT TTTAGCATAATGGACCTTTTGTAT GAACTCGTCTCACGGAGAGAAGG TCTCATACAATAGGGGCAATTAAT TTTTAGCTTTTTATCGGTAAATTTT GCATAGTACATAGTTTTGAATTTT GAGAGGTTGAGTCTATGTGACAA CGAATATTTAATTGAGTATAATGTT GTTTAATCCAAATATGATATAAAAG GGTGTGGCATATGTGATTGAGCAT TCTTTTTTCTTTTCTATGGGAAGTT AAAGGTCTAAACCTTGGTATAATT TCCTTCAATGATGAGCAATCAAAG GGTTTCAGACCTGTTTATTTATGA CTCGAAAGTCGAACCCAAACCAG AACCCGAACCCGACTCAACTTGAT TTTTTTGACATGCCTAAATGGAAC TACAGATGTATTGGGGAAAATAAT TAAACTAGAAAATGGGGAAAATAA TTAAACTAGAAAATGGGGAAAACA ATTTACCTAGAATATGTTTTCAGC CAAAACAAACACTCCCAAATACAT TTCTTAGCATCCACAAATGCCGAG GAATTGCAATGGAACTCCAGTTCC TCGGTTCTTCAACGTAGAGACGTA TATAATTCTTTTTTGCACGATATCA TTAAGGTTAATTGACCTGTTITTTTC TATGAAATATAATTTAATTITTITATG CTCTTTAGTTTGTTTTACTACACAT GAATAGTTTTGGTTTTGAGTGATC ATTTTCTTACATTATTGATGCCCAG GTTTATCGTGAATTGGAAGATAGC AACCTTCATGAAATGGTCTACCAT TCAGTATCTGTTCACGGCCCCCAC CATGGGGTACCTGTGAATGCACC CTATCAACCACTCGGTGGCATCG CCCGTAAGCGACTTCAGGCCATG AAAAGTAGCACAACTTACTGTTAC GATTTTCCACTGGTACGGAATTTG AAAATTTCATCACTCCCTCCCCCG TCTTCCCCTTAATATACTTTGTCG CCCGTTATTTCATATTCCOGTTTTAT CAACCATGCAAGGATCTTCCAGG GTTCCGAATTTCATTTTTTCGTACT TCCAAAGTTTCAGGCAAACTTACT TTTTTTGACGCTGTTGTTTTCAGG CTTTCTCAACTGCCCTGAAGCAAT CATGGGCATCGGAAGCTCCGGAT GTCAAGAAACCCTCGGACAAAGC GCTTTTGAAAGTAACGGAGTTAGC GTTTGCTGATCCAAAAGGCACATG GGGAACTCCGCTTGTTCCAATAAA TCGCAAGCCTGGTATGAACGATG TTGGCATGGTAGCCTGGTACATG GAAATGTCCACCCCCGAGTTCCC TAATGGAAGAACAATAATGGTTGT AGCTAATGATGTTACCTTCAAGGC CGGATCTTTTGGACCACGAGAAG ATGCTTTCTTCCTTGCTGTTACAA ATCTTGCTTGCGCGAAGAAACTTC CTCTTATTTATCTGGCTGCCAATT CAGGAGCTCGACTTGGTGTTGCC GAAGAGCTAAAATCCTGCTTTAAA GTTGGCTGGTCGGATGAGTCAAA TCCCGAGAGTGGATTTCAGTATGT CTACTTAACCCCTGAAGATTACGA TCGTATAGGATCGTCAGTCATAGC CCACGAGTTAAAACTCGAAAGTG GAGAAAAAAGATGGGTTATAGATA CCGTTGTAGGTAAGGAGGACGGA TTAGGTGTTGAGAACCTATCGGGA AGTGGTGCTATAGCCAGTGCATA CTCAAGGGCTTACAAGGAAACATT TACTCTGACTTTTGTAACCGGAAG AACGGTCGGTATTGGTGCCTATCT TGCTCGTCTTGGGATGCGTTGTAT ACAGAGGCTTGACCAGCCTATAAT TCTCACGGGTTTTTCTGCGTTAAA TAAACTTCTCGGTCGGGAGGTTTA TAGTTCACACATGCAACTTGGTGG ACCGAAGATTATGGGCACAAACG GGGTAGTTCATCTTACAGTATCCG ATGATCTTGAAGGCATTTCATCTA TCTTGAAGTGGCTGAGCTACGTTC CACCCTATTCAGGTGGTGAACTTC CGATTTCTCGGTGTTTAGACCCTC CAGGAAGACCGGTTGCGTATTTG CCTGAAAATTCTTGTGATCCTCGT GGTGCTATATCTGGTACGGTTGAC TCCACCGGTAAATGGTTTGGGGG TATTTTCGACAAGGATAGTTTTGT GGAAACCTTAGAAGGATGGGCAC AAACAGTTGTCACGGGAAGGGCT AAACTCGGAGGAATTCCAGTTGG CATAGTTGCCGTTGAGACGCAGA CTGTTATGCAAGTAATCCCAGCAG ATCCCGGTCAACTCGACTCACAC GAGAGAGTCGTACCACAAGCAGG GCAAGTATGGTTCCCAGATTCCG CATCCAAGACAGCACAAGCGCTG ATGGATTTCAACCGGGAAGAACTC CCACTTTTCATTCTAGCTAATTGG AGAGGTTTCTCGGGTGGACAAAG GGATCTCTTTGAAGGGATCCTTCA GGCCGGATCCACCATAGTTGAAA ATCTTAGGACTTATAATCAACCCG TTTITTGTTTATATCCCTATGATGGG GGAGCTTCGAGGAGGCGCATGG GTGGTCGTCGATAGTCGAATTAAT TCCGACCATATAGAAATGTACGCC GACCAAACAGCTAAAGGAAATGT GCTTGAACCGGAAGGAATGATTG AGATTAAGTTCCGAACCAAGGAAC TTCTCGAGTGTATGGGAAGGCTT GATCAACAACTCATCGGTCTCAAG GAAAAACTAGCCGAAGCCAAGAG CTCTAATTCCTACAATAAAATCGA GCCCCTGCAGCAACAAATAAAAG CCCGTGAGAAGCAACTATTGCCT CTATATACTCAAATAGCCACCAAA TTTGCCGAGTTGCACGATACGTCT TTAAGGATGGCTGCCAAAGGAGT CATTAGGGACGTCTTGGAATGGA AAAGCTCGCGTTCGTTCTTTTACA AAAGATTATACAGGAGAGTTATGG AGGAATCACTCGTCAAGACTGTTC GAGATGCTGCAGGTGAACGGTTG ACCCATAAGTCGGCTTTGGAGTTG ATCCAAAAATGGTTCAATGAGTCG AATATTTCCGGAGAGGCTTCCGAT GCTTGGGCTGATGATGCGGCCTT CTTTAAGTGGAAGGACAATACCGC CAACTACGAGGAGAAGTTGAAAG AGTTGCGCGTTCAGAAGGTATTG GATCAGCTGTCGAATATTGGAGAT TCGGCAACTAATTTGAGGGCTCTG CCTCAGGGTCTTGCTGCCCTACTT CAAAAGGTAATCTGATTTATTITTAT GTACATTCTTTGTTCTTTCOTCGTTT GGGTTGGATGTCGCTTTTGTAACG GGTCGGGTCGGATCAATATTTTAA TGGGCCGGGTCAAGTCATGTCAA ATTAAATTGGGCTTATGGGCTTTT TGTTTTGAGGTTGTCTCACCGTGA GACGGTCTCATACAAGACGGGCA GAAATCTAAAACAAAAAGTGGTAA AAGGCCCTTTAATGTTCTGACCTG TTATTGACCTGACCCACCGATGAC CCATTAAAATGTAACCAGACTCTT GACCCGTCGGGTCAACCCACCCT GTTAAACTCCTTATTCTAATTGCAC ACAAAATCTTTGGGAGATGTTTITG ATATCACACCTCAAAAAAACTCGG AAAAACTCCTATTAATTCCTACGAT AAACATACATCCTCGATGCCATGT ATATTTTTCGATATCTACTTGTTTT TCTATTGACATTTTGCTACGGAGA AGTGACGTTTTAGATTGAACGCAG GTGGATCCATCGAGTCGAGAAGA ACTAGTCGAGGAACTCCGAAAAG TGCTCACTTGATTTCGCAACCGTT GATGGTCAAGTGAAACCTTCTTGG TTTCATCATGGTAGAAAATATTATT AGGCAAATCTATAATTCTAGTTAC ATCCATTGTTTTAGACAATAGTATT GAACTAATTTATTTAATTAAATTGT ATAAATAGGAGACCTTGAATTCAT TTGAATTAAGTGGCTTATGCTTGC ATTATTTTGTATTGAATCAAATAAT TATTTACATACTTTTGATTATTAAT AATGGTAAATCCTCAAAATTTGAG GGATTTGTTCCTACAATGAAATCA AGGACAAAATGTATAGTTTGAGGG AATGGTGCTTGTACACTTGTCTAA ACAATAACAGGTGCTCTCTTGAGA GACCGTCTTATGTAAAGACGACTC
TCAAAAGTTCAGCCCAAATCTA 14 Amaran- |gD- /9312 ATAGCTCCACCAGAAACGGTGAA thus pal- | NA- GAAGCTTGAGCAAGCAGCTAGAA meri Con- GATTGGCTTTATGTGTGGGTTATG tig TTGGCGCAGCTACAGTTGAATATT
TATACAGCATGGAAACAGGCGAG TTCCATTTCCTTGAGTTGAATCCT CGGTTACAGGTATGGAGCTTCCC CAACTTCTTTTAAGTACCCATTATG TAACTGCATATTTATGTAATCCCTC CATTCCAAATTAGTCGCTATGTAT TCCTATGGGGATGTCCCAAATTAG TTGCAACGTTTCTGTAATATGGTA AAGTTTTCCCCTCCAAACCTTAAA ACCTAGTTGACCATAATCTAACTA AACCCAATTCTCGACCCACTTTGA AAAACAGGTCAAATGTTGGTGTTT GAACCACCTTTGAAGAAATTTAAG ATTTTGGGTTGGTAATGCTTATTA GAGATTTGGGTTTGTGGCATCGG CATTATTTTGGTGTCGATTTGCAA ATGATATCCCGGGATTTCGAACTA GGAGGGGATTCAATTGGTTTTTGA GGAATTTATGTAATTATTCCTTTAA TTAGTGATCATTGAATTGATTGTAT TTGTGTTGGGGAATTGGACCCGT GAAGAAAAAAATGACGGGTTAGCT TTTGGATTAGTGAGTGATTATGTG AGTTTAATTTGTCTATGAATGGTC AATTTCAAGCAACATTTTCTGTTTITT AGCTTAGTAATTTTTGGGATGCGA TTGAACATTTGAGCACCTTCTGGA TTATTAACAGAAATGATCATCGAA ATTGATTTTTTTAGTTGTTGACAGT AGAATAGTAACAGATAAGGTAGAA TAATACAGTATAATCTTTAGTTGC GACAATTTCCAACGTTTTTATAATA GCTAAAGCTACATTCTCATGTTGC TTGATGAAAGTGACTGTATTTATT CCGTGTGCTTATACAGGTGGAGC ATCCTGTTACTGAGTGGATTGCCG AGGTAAATCTTCCAGCTGCTCAAG TTGCAGTTGGCATGGGTATCCCA CTTTGGCAAATTCCTGGTAAATGT CCAGTACTCTTITTTCGGTTATGT AACTTATATATTATATCTAATTCTT ATTTACGAACCGAATTGATCACAC ATTTTTAAAACAGAAATCCGTCGG TTCTATGGGAAGGAACATGGTGG GGGTTATGATACTTGGATGAGGA CATCTGCTTTGGCTACTGCTTTTG ATTTTAACGAGGCACAGTCGGTGA AACCTAAAGGTCATTGTATTGCTG CGCGTGTGACAAGTGAGGATCCC GATGACGGTTTTAAGCCTACAAGC GGGAAAGTACAGGTTAGACCATC CTGGTTTTGTCGATTTACTTCCAC AATTGGTCTTGTTTTITATTTTGCCOT TTGCGGCGAAGAATTTTCTTTAAT GGGTGCTTTGTTTAGGAGCTGAG TTTTAAAAGTAAACCGAATGTGTG GGCCTACTTCTCTGTTAAGGTATT TTCCATATTTCTTTAATTCTITTGAT TTTCGCGTTAACAATTTCAGTTCA CTCCATTATGGGTTTGATGATGAT AAACACTTTTATTTGCAGTCTGGG GGAGGCATTCATGAGTTCTCGGA TTCTCAATTTGGTAAGTTAATGGT GCAAACTCTTGTCAGTAATGTTAA CTCCAGTTTCACATGATTTGCTAG TCTTTTTGTGATTTGCGAATCAAAA AAGAGAATTATTGTCGGTTTTGGG CTATTTTTTATTCCATTTGGAGCCA ATGGACATTCAAAAAGCAAATAGC TAGCGAATTTTGTTGATATTCTGG AGGTGTATATTGATGAGAATTTTA CAATAAATTGCTGCTGCTGCACTG TGCTATATTTTGGAAACACTGAAT GACTTTCAATTGTTTGTAAAGTTTG CATATTCGAGTCACAACATGATGT CATAATGAAATGCGAGCGGTTTTITT ATTAAATAATAGAGCCGTAGTGTA AAAACAAGGCCGCATTGCATCGT GTTGGCTGCATTGTAAAGGTTTTC AAAAACAATGAACTGATATTTCCC ACGTTGTAAAGGCATAAAACATTG CGTTTAGGGAAATATCAAAGAATA TCTTAAGGTTTCAACCGATATTTA GGTGGTGCAATGACCGCATTACT CCCGTTACCGCATTACCGTTCCTT GCTGCGATCACGATCGTTACCGC ATTTTTACACTATGAATAGACCTTC AGTTCATATTTTATGATGGCTAAAA TCAATTACTTGGTTAAAGGTATATA CGAAGGCTAACAAAAGCATTTCTT TACAGGCCATGTTTTTGCATTTGG TGAAAACCGAGGTTTGGCCATAG CAAATATGATTCTTGGATTAAAAG AAATTCAAATTCGTGGAGAAATTC GAACTAATGTTGATTACACCATCG ATCTTTTAAATGTGAGTTTGAATGT AATTCTTGTTGTCTTITTTITAGTITTT TCGCCTTTCTTCTGTTAAACCOTTT GAAGTTCTCACACTTAACTITTITIT TCCTCCAGTGTTTGGATTATAGAG AAAACCAAATTCATACAGGTTGGT TGGATAGTAGAATTGCGATGAGG GTCAGAGCTGAAAGGCCACCTTG GTACATCTCTGTTGTGGGAGGAG GGCTTTACGTATGTACAACTTTTT CACAGCTATCATTAATTTTTCCGTT GTTATGATCTGTGTTACTTGGACT CGGGTTGTTGGATACTGGTATGT GTCCACGTGTCGGATACGTCTAAA TATTCAATTTTACGCCTAAAATGAA GTATCTAAGTGCCATGTCCGAGCA TCAAGGATCGGACACGGGTACGT GAAGCCAAATGAAGAGTCCGAGT AACATAAGTTATGATTAATGTTAAA TAACTTGTTTTCTTTATCCTCTATA TCCAGAAAGCATCGACTAGTAGTG CAGCGACTGTTTCAGAGTATATAG GCTATCTTGAAAAAGGTCAAATTC CTCCGAAGGTATGTAACATACAAT TGGTTGGCGGGTGTTTAGATTAAC TTATTCTATTAATATCAATTATACT TTCAGTGTTCTGCTTTAATTCTGG TTTCATGATTGCAGCATATATCAC TCGTCCACTATGAAGTTGCTCTAA ATATCGAGGGGATGAAATATACCG TATGTTCCATGCCATTCGTACTTT CCTCGTGAATTTTTGTTATGGATG CTATTTTTGACATTTTCTTTCTAAA TATATTTTCTTGAAATTAATGAACA TGTCGTTTCGGATTGCCAGATTGA GATGATTAGGGGTGGACCAGGAA GCTACAAAATGTGGTTGAATGGGT CCGTAGTTGAGGCGGAAATACAT ACTTTAAGAGATGGGGGTCTCTTG ATGCAGGTATCAAATGTTTTITTGA TATTTITTITTITCTGATATACGGTAT TTATATTTTATATCCAAAGCATGGT GATAATACCCTGGATTTGTAAAGC ATTAGATAATGTGTTATCAAACAA GTAGAATGTAGTTTTGTGAAATCG TGAAGCGTTTAGTTTAGATTTAAAT TTTAATACTCCTACAATGCTTGGG ATATTAATCAATAATCATGCTTCAA ATAGTAAAGAGAAATATTGTCATA GACTCATAGGTATAATGGCTCGTT AAATCATATGCACTTCTTGTTTATG TGAAGTCCGAGTTGGTGTTTGCAA TCAACGTTTGAAATCAAGGGCATA GTGCTAAATCTCGAATGTGGTCAC TTTTGTGGTCAATGTAGATGGTTT CATTTCTATCGTGGTATAAATATG GGTCGCAGTAATCTTAAGAACCTA TATAGTAGACGATAACTTGTTATTA AAAGGGTAAAGGCTGCATACATC CGATGTCCCATTTACCCGGTCTAG ATGTGAGCTACTTGGGGTTATTGT TATTGAAGTTAAAGATACAAGAGG GATTACTGTTTGAAAAAACGGAAT ATTTGAACTACAAAAAAAGTAATTA GTTTAGGTACTAGTTCGTTCTAGC CCATATAACACATTTTAAAAAAATA TATGAAAAAGGGCTTTCAATGTCA TGAACGGAAGGGAGCAAATGGAC AGTGGAAGAGTCAACAAAGATTAC ATATGATTTATGAATTCTCTTTCGT TGTTTAAAAAACTTTGAAATTGAAA ATTGTTGGCTTTTTGTTGAAGAAA CGATGTGTGTCAGTTGAAATCAGA ATATTTAAACTACAAAAAAAGCTAT TAGTTTATACACAATACACTTGTTC GTTTAAACCCATATAGTACATTTAA ATAATTATTTGAAAAGGGCTGTTA ATGTGTGAAAACTTTCGATATGTT GATCTGATTGGATATGTGTCATAC CTTGAAACGTCATGCAGTTGGAC GGAAACAGCCATGTGATATATGCC GAGGAAGAAGCTGCAGGAACTCG CCTTCTGATTGATGGAAGAACTTG TTTGCTTCAGGTAATGCCGTGTGA TTCTCTTITITITITITITITTGTGAA TTCTAAACCTTAAAAATCATTCTCC ACCAAACTTGTTCATTTTTTCATAT AGAACGATCACGATCCTTCAAAGC TGATTGCGGAGACACCGTGTAAG CTTATGCGGTATTTGGTACCAGAT AACAGTCACATAGATGCAGATACT CCGTATGCTGAAGTTGAGGTCAT GAAGATGTGTATGCCTTTGCTTTC CCCAGCATCCGGTGTTTTACAATT TAAGATGTCCGAAGGTCAAGCTAT GCAGGTATGCATCATTTTAATCGT AAATTCAGCAACCTCGTTTATATT GGATTCTAAATATGGTCTTGCTGT GTAGGCTGGTGAACTCATAGCTA GTCTAGAGTTGGATGATCCTTCAG CTGTAAGAAAAGCCGAACCTTTCA GTGGAAGCTTTCCTGTCATGGGC TCACCAACTGCAATATCTGGAAAA GTTCATCAGAGGTGTGCCGCAAG TTTAAATGCCGCTCGGATGATTTT GGCTGGTTATGAACACAATATAGA TGAAGTAAGTTTCAAACCACCATT TCATTTTTCATCAACATAGTTTTTA GGCTAGCCTCTTAATGGGTTGATG CCATAGTGTAAAAACAAGGCCACA TCGCATCACGTCACCGCGTTGTAA AGGATTTCAAAAACAACGAACCGA TATTTCCCACATTGTGGGCTGTAT CAAGGGATATTTTATGGTTTTGAC CGGTATTTAGGCGTTACAATAACC GCATCACTCCCGTTACCGCATCAT TGTTCTGTTACCGTGATCATGACC GTTACCGCATTTTTACACTATGGA TGCCGAACCTTGAGATGCATTTCC CATTTTTCAATAGAGCCCCTAGTT TTTITCTTCCTGTTTGGAAATTITTT TACATGTGAGCCTTTTATTTTCTCA GGTAGTACAGAGTTTGCTGGAAT GCCTTGATAGTCCCGAACTTCCAT TCCTTCAATGGCAAGAATGCTTGT CTGTGCTGGCAACACGACTCCCC AAAGATCTGAGATACGAAGTGTGT ATTCTATCATCTGTTCTTGATTTAG TTATTTATATTTCCTTATAATAATTT TGAACTTTTTCCTCGGAATTTACA GTTGGAATCAAAATCTAGAGCTTT TGAAGCGATTACCAACACCCCAAA CATAGAATTTCCTGCTAAGTTGTT GAAAAGTATTCTTGAGGTTAGTAC CTCACTTTGTTACCTTCTGTAAATT ATTCACTCGGCGAGTTACTCATGT TAGTAACAAGTTTATTCTTCATAG GACCATTTAAACTCATGCCAAGAG AAAGATAAAGGAGCTCAAGAGAG GCTTATTGAGCCTCTTATGGTTCOT TGTAAAGTCTTACGAAGGTGGGC GAGAAAGTCATGCTCGTTTITTATTG TTCAATCTTTATTTGAAGAGTATTT ATCCGTTGAAGAATTGTTTAGCGA CAATCTCCAGGTTTGTCCATCTAT CTAGAGCAATTTGATTATGATGTT TTTTTAAAGTTCATAAATTTTAGCT TGGTGCCACACCGTCAGTGGCTG ATGATCGTCGCTTTGTGATCATTA AGCTTTTAAAAGCTGTCTCCTGTT CTCCATCACTATTTTTAGAAATTTT GAGTTCTGATGTATATACTCGGTA CCTGAGGGACTCTTTGGCCGCTT TCTTCTTTATGGGTATGAATTGCC TCCTTCCTTCCCTCCCCAGATCOCT GATCATAGTTTCTATGAGCGGGAT ACATTGGGTATGATGATGATTATT ATTATTATTATCGCTATTTGAACAA TTTTTCTTATGTTATTTAACTCCTT TTTGTTTTTGGCAACCGCTTTCTC AGCCTTATCTTGTCAAGGGAAGTG TCAGGATGCTGTGGCACAGATCA GGTTTCATAGCTTTATGGGAATTT GTTGAGGAGAATATTGACCGAACA AATTTTTCTGATGATCTGACTACAA ACAGTGGGAACCATAGTGAGCGA AAGTGGGGGGCCATGGTCGTTAT TAAAACTCTTCAGTTCTTGCCATC GGTGATTGCTGCAGCATTGAGAG AAACAACTCATAGTTCCGATCAAT CAACTTCCACTGGCTCTATAGAAT CAGTCATCCATGGAAATATGCTGC ACATTGCACTAGTGGGGGTGAAC AACCAGATGAGCTTGTTGCAGGAT AGGTATATAAGACTAGCCTGTAAC ATATGGTGTAATAATCTTTATTATG TAACCTTGTGCTTCTAATGTCCTTT ATTTCTATGGACTATATTGAAGTA CACTTCTTGTTCATGTGATGTTGA TGTTGATAATTGCTACCGGGTCAA TCGAAAACAACCTCTTTGTTATCA CTTGAGGTGTTCAAAATAGACCCG ATGACTCGATATTCATCAGATCTT GTAACTGAACTCGACTTCAAAATG AATTTAAAATTATATAAAAATCAAT ATGGACACAAGACCGGATATCAAT CCGACCCGAAATAGTTGACTCGA AATCAACTTGATGATCCGAATGAA CACCTCTAGTTATCACTAACAAGG GTCAGATTGCGTACATCAAACCCC TCAAATCCTGCTTAGGTGGGAGCT TGTCAATGGCTTAGGGGTAACGG GAATGTGTGTGCTATGTACATTGT GCATCTATTCTTATACTTATGTTGA GTTTTTTGGATCAAATATAAAGAA CTTAACTTTTGTATTTTCTTGATGT GGTGTAGTGGTGATGAAGATCAG GCTCAAGAGAGAATCCATAAATTG GCCAAAATTCTGAGAGAGCAAGA AGTGAGTTCAGCCCTTCGTGCTG CTGGTGTTGGTGTGATTAGTTGCA TCATACAGAGAGATGAAGGGCGA ACTCCGATGAGGCATTCATTCTAT TGGTCAGCAGAAAAACAATATTAT AGTGAGGAGCCTTTACTACGTCAT TTGGAACCCCCTCTATCTATGTAT CTCGAGCTGGTACTAGTCTCTGAA CCGATTGCCTTTCTTCTGCTTTGST TATTCTGTGTGATATTTCGACTTAA GTCTAATTTACATCGTTTTGTACAT TTGTTATCCAAAGCACGTTAAAAG ATACTTCCTTCGTTTTTTTACAAGC ACCCAAACACCTTTTTACGCAGCC CAATTGGTTTGTCGGGTTGCTTAT ATATAGAATTATACTCAACTTAAAA ATTATAAAATTTGATATTATGAAAG TATTCGACGTGACGAATTAAACAA AATCCCATATGACTATGTTITTITTC TCGTTTGATAGCNNNAATATGTAA AATACTATCGAATGATGAATAGTG TAAAAACTGGTTTGGGTGCAACTA AAAAAATGGAGGAAGTATAATTAT GCAGCCAAAATTGATGGCTTTTAA CTTTTCATCAAATCAGGACAAGCT TAAGGGTTATGAAGATATCAAATA TACTCCTTCCCGTGATCGTCAATG GCATCTTTACACAGTTATTGATAA ACCATTCATTCGGAGGATGTTTTT GAGAACCCTTGTAAGACAACCCAT CTCTGAGTTCACAGGCGTCGAAC TAAGCGCTCTTGAAACACAAAAGC CTATCTCTTTCACTTCAAGAAGCA TCCTAAGGTCCTTAACAACCGCCA TGGAGGAGTTGGAGCTCAATGCA CATAGTGCTTCACTGAAACCCGAT CACGCTCATATGTACTTGTACATT GTCCGAGAGCAACAAATATACGAT CTTGTGCCATATCACAGGTATCTA TTGCTGCGTGCCTCAACTTITTITT GTTTATTATTGGTCATTAGTACAC CTTATTCTTAGAAGAAACTTTITTTC GGCCAATTATTTCCAGGGAGGTG AACATAGATCACCAACAAGAAGAG GCTTCAGTTCAATTCTTTTTGGAA GATCTCGCGCATGAAATCCATAGT CTTGCTGGTGTAAGGATGCATAAA CTAAATGTTTGTGAGTGGGAAGTG AAACTTCGGGTATCATCTCCCGG GAAAGCTAATGGTTTATGGAGGGT GGCAGTTACTAATGTGACTGGTCA TACCTGTTCGGTACATGTAAGTCA TAATTTTGAGAACCTCTTTITTTGAT CAAGTCACAATTTTAATTTTTCACA AATTCTTGTATGAGACGGTCTCAC CGTGAGAAGCGCCCCATACTTGG ATTAAATAGCCGAATAAAAGAAAC TTTTAGCATAATGGACCTTTTGTAT GGACTCGTCTCATGGTGAGAAGG TCTCATACAATAGGGGCAATTAAT TTTTAGCTTCTTATCTGTAAATTTITT GCATAGTACATAGTTTTGAATTTT GAGAGGTTGAGTCTATGTGACAA CGAATATTTAATTGAGTATAATGTT GTTTAATCCAAATATGATATAAAAG GGTGTGGCATAAGTGATTGAGCA TTCTTTITTCTTTTCAATGGGAAGT TAAAGGTCTAAACCTTGGTATAAT TTCCTTCAATGATGAGCAATCAAA GGGATTCTAACCTGTTTATTTATG ACTCGAAAGTCGAACCCAAACCA GAACCCGAACCCGACTCAACTTG ATTTTTTTGACATGCCTAAATGGA ACTACAGATGTATTGGGGAAAATA ATTAAACTAGAAAATGGGGAAAAT AATTAAACTAGAAAATGGGGAAAA CAATTTACCTAGAATATGTTTTCAG CCAAAACAAACACTCCCAAATACA TTTCTTAGCATCCACAAATGCCGA GGAATTGCAATGGAACTCCAGTTC CTCGGTTCAACTTAGAGAAGTATA TAATTCTTTTITTGCACGATATCATT ATGGTTAATTGACCTGTTTTTTCTA TGAAATATAATTTAATTTITTATGCT CTCTAGTTTGTTTTACTACACATGA ATAGTTTTGGTTTAGAGTGATCAT TTTCTTACAATATTGATGCCCAGG TTTATCGTGAATTGGAAGATAGCA ACCTACATGAAATGGTCTAC-
CATTCAGTAT Amaran- |gD- |5302 AACCTTGTGCTTCTAATGTCCTITT thus pal- | NA- ATTTCTATGGACTATATTAGAGTA meri Con- CACTTCTTGTTCATGTGATGTTGA tig TGTTGATAATTGCTACCTGGTCAA
TCACAAACAACCTCTTTGTTATCA CTTGAGGTGTTCAAAATAGACCCG ATGACTCGATATTCATCAGATCTT GTAACTGAACTCGACTTCAAAATG AATTTAAAATTATATAAAAATCAAT ATGGACACAAGACCGGATATCAAT CCGACCCGAAATAGTTGACTCGA AATCAACTTGATGATCCGAATGAA CACCTCTAGTTATCACTTACAAGG GTCAGATTGCGTACATCAAACCCC TCAAATCCTGCTTAGGTGGGAGC AGTGTCACATGATTCGCTAGTTAA TTCGCATGTCTCGATTCGAGATTC GCTCAAAATGGACCAAAAATGGC CCAAAAACGACCAAAATTCGCTTT TTTCAATTCGCGATTCGCAGAGAG ATTAACGAATTATGTGACAGTGGG TGGGAGCTTGTCAATGGCTTAGG GGTAACGGAATTGTGTGTGCTATG TATATTGTGCATCTATTCTTATACG TATGTTGAGTTTTTTGGATCAAATA TAAAGAGCTTATCTTTTGTATTTTC TTGATGTGGTGTAGTGGTGATGAA GATCAGGCTCAAGAGAGAATCGA TAAATTGGCCAAAATTCTGAGAGA ACAAGAAGTGAGTTCAGCCCTTC GTGCTGCTGGTGTTGGTGTGATA AGTTGCATCATACAGAGAGATGAA GGGCGAACTCCGATGAGGCATTC ATTCTATTGGTCAGCAGAAAAACA ATATTATAGTGAGGAGCCTTTACT ACGTCATTTGGAACCCCCTCTATC TATGTATCTCGAGCTGGTACTAGT CTCTGAACCGATTGCCTTTCTTCOT GCTTTGTTATTTTGTGTGATATTTC GACTTAAGTCTAATTTACATCGTTT TGTACATTTGTTATCCAAAGCACG TTAAAAGATACTTCCTTCGTTITTIT TACAAGCACCCAAACACCTTTTTA CGCAGTCCAATTGGTTTGTCGGG TTGCTTATATATAGAATTTTACTCA ACTTAAAATTATAAAATTTGATATT ATGAAAGTATTCGACGAGACGAAT AAAACAAAATCCCATATGACTGTT TTTTTCTCGTTTAATAGCTGTAATA TGTAAAATACTATCGAATGATGAA TAGTGTAAAAACTGGTTTGGGTGC AACTAAAAAAATGGAGGAAGTATA ATTATGCAGCCAAAACTGATGGCT TCTAACTTTTCATCAACTCAGGAC AAGCTTAAGGGTTATGAAGATATC AAATATACTCCTTCCCGTGATCGT CAATGGCATCTTTACACGGTTATT GATAAACCATTCATTCGGAGGATG TTTTTGAGAACCCTTGTAAGACAA CCCATCTCTGAGTTCACAGGCGT CGAACTAAGCGCTCTTGAAACACA AAAGCCTATCTCTTTCACTTCAAG AAGCATCCTAAGGTCCTTAACAAC CGCCATGGAGGAGTTGGAGCTCA ATGCACATAGTGCTTCACTGAAAC CCGATCACGCTCATATGTACTTGT ACATTGTCCGAGAGCAACAAATAT ACGATCTTGTGCCATATCACAGGT ATCTATTGCTGCGTGCCTCATTTT TTTTTGTTTATTATTGGTCATTAGT ACACCTTATTCTTAGAAGAAACTTT TTTCGGCCAATTATTTCCAGGGAG GTGAACATAGATCACCAACAAGAA GAGGCTTCGGTTCAATTCTTITTG GAAGATCTCGCGCATGAAATCCAT AGTCTTGCTGGTGTAAGGATGCAT AAACTAAATGTTTGTGAGTGGGAA GTGAAACTTCGGGTATCATCTCCC GGGAAAGCTAATGGTTTATGGAG GGTGGCAGTTACTAATGTGACTG GTCATACCTGTTCGGTACATGTAA GTCATAGTTTTGAGAACCTCTTITTIT TGATCTAGTCACAATTTTGATTITITT CACAAATTCTTGTATGAGACGGTC TCACCGTGAGAATCACCCCATACT TGGATTAAATAGCCGAATAATAGA AACTTTTAGCATAATGGACCTTTT GTATGAACTCGTCTCACGGAGAG AAGGTCTCATACAATAGGGGCAAT TAATTTTTAGCTTTTTATCGGTAAA TTTTGCATAGTACATAGTTTTGAAT TTTGAGAGGTTGAGTCTACGTGAC AACGAATATTTAAGTGAGTATAAT GTTGTTTAATCCAAATATGATATAA AAGGGTGTGGCATATGTGATTGA GCATTCTTITTITCTTTITCTATGGGA AGTTAAAGGTCTAAACCTTGGTAT AATTTCCTTCAATGATGAGCAATC AAAGGGTTTCAGACCTGTTTATTT ATGACTCGAACCTGAACCCGACT CTACTTGATTTTTTTGACATGCCTA AATGGAACTACAGATTTATTGGGG AAAATAATTAAACTAGAAAATGGG GAAAACAATTTACCTAGAATGCGT TTTCCGCCAAAACAAACACTCCCA AATACATTTCTTAGCATCCACAAAT GCCGAGGAATTGCAACGGAACTA CCGATCCTCGGTTCTTCAACGTAG AGACGTATATAATTCTTITTITTGCAC GATATCATTAAGGTTAATTGACCT GTTTTTTCTATGAAATATAATTTAA TTTITATGCTCTTTAGTTTGTITTITA CTACACATGAATAGTTTTGGTTTT GAGTGATCATTTTCTTACATTATTG ATGCCCAGGTTTATCGTGAATTGG AAGATAGCAACCTTCATGAAATGG TCTACCATTCAGTATCTGTTCACG GCCCCCACCATGGGGTACCTGTG AATGCACCCTATCAACCACTCGGT GGCATCGCCCGTAAGCGACTTCA GGCCATGAAAAGTAGCACAACTTA CTGTTACGATTTTCCACTGGTACG GAATTTGAAAATTTCATCACTCCC TCCCCCGTCTTCCCCTTAATATAC TTTGTCGCCCGTTATTTCATATTC CGTTTTATCAACCATGCAAGGATC TTCCAGGGTTCCGAATTTCATITITT TTCGTACTTCCAAAGTTTCAGGCA AACTTACTTTTTTTGACGCTGTTGT TTTCAGGCTTTCTCAACTGCCCTG AAGCAATCATGGGCATCGGAAGC TCCGGATGTCAAGAAACCCTCGG ACAAAGCGCTTTTGAAAGTAACGG AGTTAGCGTTTGCTGATCCAAAAG GCACATGGGGAACTCCGCTTGTT CCAATAAATCGCAAGCCTGGTATG AACGATGTTGGCATGGTAGCCTG GTACATGGAAATGTCCACCCCCG AGTTCCCTAATGGAAGAACAATAA TGGTTGTAGCTAATGATGTTACCT TCAAGGCCGGATCTTTTGGACCA CGAGAAGATGCTTTCTTCCTTGCT GTTACAAATCTTGCTTGCGCGAAG AAACTTCCTCTTATTTATCTGGCT GCCAATTCAGGAGCTCGACTTGG TGTTGCCGAAGAGCTAAAATCCTG CTTTAAAGTTGGCTGGTCGGATGA GTCAAATCCCGAGAGTGGATTTCA GTATGTCTACTTAACCCCTGAAGA TTACGATCGTATAGGATCGTCAGT CATAGCCCACGAGTTAAAACTCGA AAGTGGAGAAAAAAGATGGGTTAT AGATACCGTTGTAGGTAAGGAGG ACGGATTAGGTGTTGAGAACCTAT CGGGAAGTGGTGCTATAGCCAGT GCATACTCAAGGGCTTACAAGGA AACATTTACTCTGACTTTTGTAACC GGAAGAACGGTCGGTATTGGTGC CTATCTTGCTCGTCTTGGGATGCG TTGTATACAGAGGCTTGACCAGCC TATAATTCTCACGGGTTTTTCTGC GTTAAATAAACTTCTCGGTCGGGA GGTTTATAGTTCACACATGCAACT TGGTGGACCGAAGATTATGGGCA CAAACGGGGTAGTTCATCTTACAG TATCCGATGATCTTGAAGGCATTT CATCTATCTTGAAGTGGCTGAGCT ACGTTCCACCCTATTCAGGTGGTG AACTTCCGATTTCTCGGTGTTTAG ACCCTCCAGGAAGACCGGTTGCG TATTTGCCTGAAAATTCTTGTGAT CCTCGTGGTGCTATATCTGGTACG GTTGACTCCACCGGTAAATGGTTT GGGGGTATTTTCGACAAGGATAG TTTTGTGGAAACCTTAGAAGGATG GGCACAAACAGTTGTCACGGGAA GGGCTAAACTCGGAGGAATTCCA GTTGGCATAGTTGCCGTTGAGAC GCAGACTGTTATGCAAGTAATCCC AGCAGATCCCGGTCAACTCGACT CACACGAGAGAGTCGTACCACAA GCAGGGCAAGTATGGTTCCCAGA TTCTGCATCCAAGACAGCACAAGC GCTGATGGATTTCAACCGGGAAG AACTCCCACTTTTCATTITTAGCTAA TTGGAGAGGTTTCTCGGGTGGAC AAAGGGATCTCTTTGAAGGGATCC TTCAGGCCGGATCCACCATAGTT GAAAATCTTAGGACTTATAATCAA CCCGTTTTTGTTTATATCCCTATGA TGGGGGAGCTTCGAGGAGGCGC ATGGGTGGTCGTCGATAGTCGAA TTAATTCCGACCATATAGAAATGT ACGCCGACCAAACAGCTAAAGGA AATGTGCTTGAACCGGAAGGAAT GATTGAGATTAAGTTCCGAACCAA GGAACTTCTCGAGTGTATGGGAA GGCTTGATCAACAACTCATCGGTC TCAAGGAAAAACTAGCCGAAGCC AAGAGCTCTAATTCCTACAATAAA ATCGAGCCCCTGCAGCAACAAAT AAAAGCCCGTGAGAAGCAACTATT GCCTCTATATACTCAAATAGCCAC CAAATTTGCCGAGTTGCACGATAC GTCTTTAAGGATGGCTGCCAAAG GAGTCATTAGGGACGTCTTGGAAT GGAAAAGCTCGCGTTCGTTCTTITT ACAAAAGATTATACAGGAGAGTTA TGGAGGAATCGCTCGTCAAGACT GTTCGAGATGCTGCAGGTGAACG GTTGACCCATAAGTCGGCTTTGGA GTTGATCCAAAAATGGTTCAATGA GTCGAATATTTCCGGAGAGGCTTC CGATGCTTGGGCTGATGATGCGG CCTTCTTTAAGTGGAAGGACAATA CCGCCAACTACGAGGAGAAGTTG AAAGAGTTGCGCGTTCAGAAGGT ATTGGATCAGCTGTCGAATATTGG AGATTCGGCAACTAATTTGAGGGC TCTGCCTCAGGGTCTTGCTGCCC TACTTCAAAAGGTAATCTGATTTAT TTTATGTA-
CATTCTTTGTTCTITTCTCO [16 faneer [ao [1609 | AnaTeATTOCcATTACOGOEATTT thus pal- | NA- AGTACCACTAACCAAACGGGACG meri Con- GTAAAGTTTTGCTTACTACAATATC tig TTCTTAGCTCATAAGCTCAGAACC
TTACTTGAATTTTGACAATGTGTGT CTAGCTATACTTTCAATAAGTATTT AAGAATTCATTTTCTITITATCTAT GTAAAGTTGCATATGATGTTTGTT ATAAAGGGTCAATCAAAAAACTAT CTCTTTGTTATTAGTAACAAGGGT AACTGGGTAAGGTTATGTACATCC AATCCCTCCAAACCCTTTTTGGGT GGGAGCTACTTAATGGCGCTGGGÇ ACAATGGAAGTTTTTGTTTGTCGA ATTCAAGCGGGGAAGTTTGTTTAG AATGAATGTTATTTCTAAAAATAGA TGGTATAAGTATGTTAATCAACAA TTAATAATAGAGAACTGTTTITATTG GTGTGATAAACAGTTTCAGGAGCA GTGGTCTCATTTTCGAGCAATACA AAAAGTGCCGTGCTTCTCTAAACA ACGACGATTCAGACATGTCTTCTC CTTCCCACAATAATGAAAACCCGA ACGGACCGATGATGCCACTCCTG AGGAATTCATCTGTAGTATCCATT GTTGATAAGTTCTGTTATGCTCTT GGAGGGACGCGGCCAATCCATAG TATTTTGATAGCAAACAATGGGAT GGCTGCTGTCAAATTTATAAGAAG TATCCGAACATGGGCTTACGAGA CTTTTGGTACTGAGAAGGCTATAT TATTGGTAGCCATGGCTACTCCCG AAGACATGAAAATCAATGCCGAGC ATATTCGAATGGCTGATCAGTTTG TTGAAGTCCCCGGAGGAACTAAC AACAATAACTACGCCAATGTGCAG CTCATTGTTGAGGTAATGTATCTT GAGATTAGAAATTTCTAGCCTGTC ATCCATAGTTACATGGAATGTGGA ACATAGCCACGTTCCGCGATTCG GGAACATTCATTCCCAATCACCAT GAAACCCGACCTAAATCGCTAAAG GTGACGTCCCGGTGTAGAACACC TTTTTTTTAAAATGTATTTITTGGCC TTCATTTACAAATTGAAGAAAGGA GGAAAAAACAAGATGTAACCCAGA AACCTAAACAAATCCACTTGAAAA TAATTTCTTAAAGCAAATTAATCAT TTTAGTTTAATTTTGTTTCAAATAT ATATTTTATACATAATGTATCTCAT ACCCAATCGTTCTTGAGTAAATCT AGGTTGCGTTCTGTGTTCCCATTC TTGTTTCCTGTTCGAAACCAAATG TCGTTCAGTTAACAATGCTGTTAT CTGCTTTACTGTGATTTATTAAATG TGTCCTTCGAAAAAAGGCAATATC AGAGCGACTTGATGCAGTATGGC CTGGCCGGGGACATGCGTAGTTT GTTATATGAGATTGCAAATTTATA GCCTTTTATATGGTAAAATCTTGT GGTAGGACTAACTTAAATCCTTTT TCTTTCAGTTAGCGGAAGTTACAC GAGTTGACGCAGTTTGGCCTGGT TGGGGACATGCATCGGAGATCCC CGAGTTGCCAGATTCATTAGCTAC GAAGGGAATTGTGTTTCTGGGCC CCCCAGCTGCATCTATGGCTGCT CTTGGAGATAAAATTGGTTCATCA TTGATTGCACAAGCTGCAGATGTC CCAACTCTTCCATG- GAGTGGTTCTCATGTACGTACTA-
CAC 7 Amaran- j|gD- |1457 GGAGACATCTTGTGCCTCTAACCA thus pal- | NA- AACCAAACCAACCTCCTTAAACTT meri Con- CTCTTCTTCTACTCACCATTTITTO tig CTCTTTTITATTGATTATTGATTATT
CATTTTAAATATACATTATATTGTA GGAATTTAATGAAATTTTCATTAAA TTCTGATAAAGTTTTGATTTTITITTT AGTGTATGAGATTTTTCTTAAGTA CCCAAATGGTAAATTTCAAGTATA ATCAAGTTTTTTAGTACCCAAAGC TCTAAATGTTACTTAAAGTTTTGAT CTTTTAATGGTTTCTTCTATTTAAT CCAATAATTTAAAGTACCCAGATT TCAATTTTTAGAATAAATTGAGTTT TTGAATTGCCCAAGTTGTAATTGT TGCTGAATTCTCTTGCTTTGATTT GGGTTTTCTGATTCTATCCCTTCOT GATTCATACAGGTATTCTGATTTITTT TCTTGCTTGATTACTTTTTGTTAGT GTATGGTTGAGCTAATTTAGTTTA TAGTAGTGTGAATTTTATTTTATTT TTTTTCAATTTTTTCAATTATTTCAA TTTGTAGAGTAGATTCTCCTATTAT GATTTGTTTTTGTAGCTGGGTTTT AATTTTTATTGTCTGATGATTTATC TTAGCAATGTTTTATTGAAGTGTAT TTTAGTTGATTCCATTTTTCCAATA GAGTGTACAAAATCGACCTGATTA ACTGAAACTGAGTATTATCCAACG GGAACAATCACTGTTACAAAATTC AAATTAGAATGTCAAGTACCGAAA TCAACCCGACCCCACATATTATAC CCGAGATCCACCCGAACACCCGA ATGAACACCTCTGAGATCATAGAG AGGATATAAGAAAAGTGAAACTAG AATGGGGAATTTAGTTTATTTAAG CTACATTGAGCAAAAATTTITTTTAG TGACTGATTATTGTAGCTGGCTTT TGTTGTATAACTCATCTAAGCAAT GTTTTTGATGTGTGTGCAGTAGCA TTGGATTGTTTTGATTITTITTGITTA TATTGTCTATACAATTCAATTCTITG AATCACACTTGACTTTTAGTTCCAT TTTCATCTTCACAAATTCTTGTGAG AGACGGTCTCAGTGTTAGACGCT CTCTGTACATGGGCTAAATAGCCC AACTAATACAACTATTAGCATACG AGCTTCTTATTTTGAAGTCATCTCT CATAAGAGTAGCTCTCTATCTITTC GTTGGGTAGATGGTAATAAACGGT AGTAATGAGGATGAAAAACAAGTG TAATTTTGGTTGGAAAATATGTTG GTTACCTTGATGGTCATGCTTGTC CAACTTAAATCATCTTATTITCITTC TCAAAATTCATTTCAATGCATTACC ATTAGGAGAGGTGATATTAGGCG GTAATGAAATTATGTAAACAAAAA AACTTTTTTGTGATTGAAGTTTCAT TGCTATAGGAACGATATCGA-
TATGGAACTTTTGATGAAATTT 18 Amaran- |gD- |1175 TTTTTTITTCCTTCCAAATTTCTGA thus pal- | NA- TCTTTAGAGTTTTAGTGATAGATTT meri Con- ATATACGTCTCTATCCCTCAGGTG tig AAAATTCCTGCTGAGAGTTGCCTA
GACGTAATTCCCGATGAAGTATAT AAAGCGGCATGTGTTTTTACTACA GAGGAAGCAATTGCTAGCTGTCA AGTTGTTGGTTATCCGGCTATGAT CAAAGCTTCTTGGGGTGGTGGAG GGAAGGGAATAAGAAAGGTAAAA TTTTTTTGGATGATGATGCTCTTAA AAGACTAAAAGGAGGTTACACATA TCCCCATTACTTGTTTATCATCAG AGGCGGAGCAAAAATTGACAAAG ATTTAAAGGCTGTGTGCAATTTCA AAAAATATGATATATTTCTAACAAC GTATCTTCAAACACTTTAAACATAC TACCTATTCTAATATTGCGGCCCC TATTTTTTTGAGGCCGTGTEGTEGGT CGAACATATTGAATATGCTTAGAA CCACTCCTGTTTATCACTAATATG CCATCTTCCACAATCAAACCTCTA CTTTTGACCCAGATTCCTTGAAAG GGATTTCGATTTAGACTCGAGCTA TGGTCAATTATTAGCAATAGCAAA AGCTTCTTAATAGTTAATAGATTCT CAAACACTTCCGTCATGCCAACAC TTTATGAAGACTCATGGGTATTCT CTCTTTTAGGTTCATAATGATGAC GAAGTACGGGCATTATTTAAGCAA GTGCAGGGTGAAGTTCCCGGCTC ACCCATATTTATAATGAAGGTGGC TTCACAGGTTAGACTTTCTTCAAC ATTGGTCCGATATTCGAGTAAATT GCATTAAAAAAGGTTAAATATACA ATTTTTTTGGATAAGTATTGTATGA GAGACTACTACTAAGATAAAGTAT TATTAATATGTGCAGAGTCGACAC TTAGAAGTACAGTTACTGTGTGAT GAATATGGCAATGTTGCAGCATTG CATAGCCGTGATTGCAGTGTCCAA AGGCGGCACCAAAAGGTGGGTCT TTGGTAGATTATGGTTATGATCTA CGGTTTCTTATTGTTTAAGAAAAAT ATTTGATATTAAGCATTATTTAGCT TGCTGAGATTTGAACTTTTCTGTT CATCATATTAACTAATCAGATCATT GAAGAAGGCCCAATAACGA- TAGCTCCACCAGAAACGGTGAA-
EE A o 19 Amaran- |cD- |/5038 AAGAACTTGTTTGCTTCAGAACGA thus rudis | NA- TCACGATCCTTCAAAGCTGATTGC Con- GGAGACACCGTGTAAGCTTATGC tig GGTATTTGGTACCAGATAACAGTC
ACATAGATGCAGATACTCCGTATG CTGAAGTTGAGGTCATGAAGATGT GTATGCCTTTGCTTTCCCCTGCAT CCGGTGTTTTACAATTTAAGATGT CCGAAGGTCAAGCTATGCAGGCT GGTGAACTCATAGCTAGTCTAGAG TTGGATGATCCTTCAGCTGTAAGA AAAGCCGAACCTTTCCGTGGAAG CTTTCCTGTCATGGGCGCACCAA CTGCAATATCTGGAAAAGTTCATC AGAGGTGTGCCGCAAGTTTAAAT GCCACTCGGATGATTTTGGCTGG TTATGAACACAATATAGATGAAGT AGTACAGAGTTTGCTGGAATGCCT TGATAGTCCCGAACTTCCATTCCT TCAATGGCAAGAATGCTTGTCTGT GCTGGCAACACGACTTCCCAAAG ATCTGAGATACGAATTGGAATCAA AATCTAGAGCTTTTGAAGGGATTA CCAACACCCAGAACGTAGAATTTC CTGCTAAGTTGTTGAAAAGCATTC TTGAGGACCATTTAAACTCATGCC ACGAGAAAGATAAAGGAGCTCAA GAGAGGCTTATTGAGCCTCTTATG GCTCTTGTAAAGTCTTACGAAGGT GGGCGAGAAAGTCATGCTCGTTT TATTGTTCAATCTTTATTTGAAGAG TATTTATCCGTTGAAGAATTGTTTA GCGACAATCTCCAGGCTGATGTG ATTGAACGTCTCCGCCTTCAGTAT AAGAAGGATCTGCTGAAGATTGTT GACATTGTACTGTCGCATCAGGGT GTTAAGAATAAAAATAAGCTGATT CTACGACTCATGGAACAGCTGGTT TACCCAAATCCCGCTGCATACAG GGGGAAACTTATCCGTTTCTCTCA ATTGAACCATACAATGTATTCTGA GTTGGCACTAAAGGCCAGTCAATT GCTTGAACAAACGAAATTGAGTGA GCTCCGTTCGAACATTGCTAGAAA CCTCTCTGAGCTAGAAATGTTTAC CGAGGATGGCGAAAACATGGATA CTCCAAAAAGAAAAAGTGCTATTA ATGAACGTATGGAGGCGCTTGTG AGTACTCCTCTAGCTGTCGAAGAT GCCCTTGTTGGTTTGTTTGATCAT AGTGATCATACACTTCAGAGGCG GGTTGTTGAGACCTATGTTCGGA GGCTTTATCAGCCTTATCTTGTCA AGGGAAGTGTCAGGATGCTGTGG CACAGATCAGGCTTCATAGCTTTA TGGGAATTTGTTGAGGAGAATATT GACCGAACGAATTTTTCTGATCTG ACTACAAACAGTGGGAACCATAGT GAGCGAAAGTGGGGGGCCATGGT CGTTATTAAAACTCTTCAGTTCTTG CCATCGGTAATTGCTGCAGCATTG AGAGAAACAACTCATAGTTCCGAT CAATCAACTTCCACTGGCTCTATA GAATCAGTCATCCATGGAAATATG CTGCACATTGCACTAGTCGGGGT GAATAACCAGATGAGCTTGTTGCA GGATAGTGGTGATGAAGATCAGG CTCAAGAGAGAATCGATAAGTTGG CCAAAATTCTGAGAGAACAAGAAG TGAGTTCAGCCCTTCGTGCTGTTG GTGTTGGTGTGATTAGTTGCATCA TACAGAGAGATGAAGGGCGAACT CCGATGAGGCATTCATTCTATTGG TCAGCAGAAAAACAATATTATAGT GAGGAACCTTTACTACGTCATTTG GAACCCCCTCTATCTATGTATCOTCE GAGCTGGACAAGCTTAAGGGTTA TGAAGATATCAAATATACTCCTTC CCGTGATCGTCAATGGCATCTTTA CACGGTTATTGATAAACCATTCAT TCGGAGGATGTTTTTGAGAACCCT TGTAAGACAACCCATCTCCGAGTT CACTGGCGTCGAACTAAGCGCTC TTGAAACACAAAAGCCTATCTCTT TTACTTCAAGAAGCATCCTAAGGT CATTAACAACCGCCATGGAGGAG TTGGAGCTCAATGCACATAGTGCT TCACTGAAACCCGATCACGCTCAT ATGTACTTGTACATTGTCCGAGAG CAACAAATATACGATCTTGTGCCA TATAACAGGGAGGTGAACATAGAT TACCAACAAGAAGAGGCTTCGGTT CAATTCTTTTTGGAAGATCTCGCG CATGAAATCCATAGTCTTGCTGGT GTAAGGATGCATAAACTAAATGTT TGTGAGTGGGAAGTGAAACTTCG GATATCATCTCCCGGGAAAGCTAA TGGTTTATGGAGGGTGGCAGTTA CTAATGTGACTGGTCATACCTGTT CGGTACATGTTTATCGTGAATTGG AAGATAGCAACCTACATGAAATGG TCTACCATTCAGTATCTGTTCACG GCCCCCACCATGGGGTACCTGTG AATGCACCCTATCAACCACTCGGT GGCATCTCCCGTAAGCGACTTCA GGCCATGAAGAGTAGCACAACAT ACTGTTACGATTTTCCACTGGCTT TCTCAACTGCCCTGAAGCAATCAT GGGCATCGGAAGCTCCGGATGTC AAGAAACCCTCGGACAAAGCACTT TTGAAAGTAACCGAGCTAGCATTT GCTGATCCAAAAGGCACATGGGG AACTCCGCTTGTTCCAATAAATCG CAAGCCTGGTATGAACGATGTTG GCATGGTAGCCTGGTACTTGGAA ATGTCCACCCCCGAGTTCCCTAAC GGAAGAACAATAATGGTTGTAGCT AATGATGTTACCTTCAAGGCCGGA TCTTTCGGACCACGAGAAGATGCT TTCTTCCTTGCTGTTACAAATCTTG CTTGCGCGAAGAAACTTCCTCTTA TTTATCTGGCTGCCAATTCAGGAG CTCGACTTGGTGTTGCCGAAGAG CTAAAATCCTGCTTTAAAGTTGGC TGGTCGGATGAGTCAAACCCCGA GAGTGGATTTCAGTATGTCTACTT AACCCCTGAAGATTACGATCGTAT AGGATCGTCAGTCATAGCCCACG AGTTAAAACTCGAAAGTGGAGAAA AAAGATGGGTTATAGACACCGTTG TCGGTAAGGAGGACGGATTAGGT GTCGAGAATCTATCAGGAAGTGG TGCTATAGCCAGTGCATACTCAAG GGCTTACAAGGAAACATTTACTCT GACTTTTGTAACCGGTAGAACGGT CGGTATTGGTGCCTATCTTGCTCG TCTTGGGATGCGTTGTATACAGAG GCTTGACCAGCCTATAATTCTCAC GGGTTTTTCTGCGTTAAATAAACT TCTCGGTCGGGAGGTTTACAGTT CACACATGCAACTTGGTGGACCG AAGATTAATGGGCACAAACGGGG TAGTTCATCTTACAGTTTCCGATG ATCTTGAAGGCATTTCATCTATCTT GAAGTGGCTGAGCTATGTTCCAC CCTATTCAGGTGGTGAACTTCCGA TTTCTCGGTGTTTAGACCCTCCCG AAAGACCGGTTGCGTATTTGCCTG AAAATTGTTGTGATCCTCGTGGGGÇ CTATATCTGGTACGGTTGACTCCG CCGGTAAATGGTTTGGGGGTATTT TCGACAAGGATAGTTTTGTGGAAA CCTTAGAAGGATGGGCACGAACA GTTGTCACGGGAAGGGCTAAACT CGGAGGAATTCCAGTTGGCATAG TTGCTGTTGAGACACAGACTGTTA TGCAAGTAATCCCAGCAGATCCC GGTCAACTCGACTCACATGAGAG AGTCGTACCACAAGCAGGGCAAG TATGGTTCCCAGATTCCGCATCCA AGACAGCACAAGCGCTGATGGAT TTCAACCGGGAAGAACTCCCACTT TTCATTTTAGCTAATTGGAGAGGT TTCTCGGGTGGACAAAGGGATCT CTTTGAAGGGATCCTTCAGGCTG GATCCACCATAGTCGAAAATCTTA GGACTTATAATCAACCCGTTTITG TTTATATACCTATGATGGGGGAGC TTCGAGGAGGGCATGGGTGGTCG TCGATAGTCGAATTAATTCCGACC ATATAGAAATGTACGCCGACCAAA CAGCTAAAGGAAATGTACTTGAAC CCGAAGGAATGATCGAGATTAAGT TCAGAACCAAGGAACTTCTCGAGT GTATGGGAAGGCTTGATCAACAA CTCATCGGTCTCAAAGAAAAACTA GCCGAAGCCAAGAGCTCTAATTC CTATGGTAAAATCGACCCGCTTCA GCAACAAATAAAAGCCCGCGAGA AGCAACTATTGCCTCTATATACTC AGATAGCCACCAAATTTGCCGAGT TGCACGATACGTCTTTAAGGATGG CTGCCAAAGGAGTCATTAGGGAC GTCTTGGAATGGAAAAGCTCGCG TTCTTTCTTTTACAAACGATTATAC AGGAGAGTGATGGAAGAATCGCT CGTCAAGACCGTTCGAGATGCTG CAGGTGAACGGTTGACCCATAAG TCGGCTTTGGAGTTGATCCGGAA ATGGTTCAATGAGTCGATATTTCC GGAGAGGCTTCCGATGCTTGGGC TGATGATGCAGCCTTCTTTAAGTG GAAGGATAATACCGCTAACTACGA GGAGAAGTTGAAAGAGTTGCGCG TTCAGAAGGTATTGGATCAGCTGT CGAATATTGGAGATTCGGTAACTA ATTTGAGGGCTCTGCCTCAGGGT CTTGCTGCCCTACTTCAAAAGGTG GATCCATCGAGTCGAGAAGAACT AGTTGAGGAACTCCGAAAAGTGC TCACTTGATTAGCGGCCGTTGATG GTGAAGTGAAACCTTCTTGGTTTC ATCATGGTAGAAATTATTATTAGG CAAATCTATAATTCTAGTTACATCA ATTGTATTAGACAATAGTATGAAC TAATTTATTTAATTAAATTGTATAA ATAGGAAACCTTGAATTCATTTGA ATTAATCGGCTTATGCTTGCATTA TTTTGTATTGATTCAATTAATAATT TACATACTTTTGAGTATTAATAATG GAAAAAAAAAAGAAAAAAAAACAA AACATGTCGGCCGCCTCGGTCTC- CATGTCGGCCGCCTCGGTCTC-
TACTGA Amaran- |cD- |1529 CGGTTGCGTATTTGCCGGAAAATT thus rudis | NA- CTTGTGATCCTCGTGGTGCTATAT Con- CTGGTACGGTTGACTCCACCGGT tig AAATGGTTTGGGGGTATCTTCGAC
AAAGATAGTTTTGTGGAAACCTTA GAAGGCTGGGCACGAACAGTTGT CACGGGAAGGGCTAAACTTGGAG GAATTCCAGTTGGCATAGTTGCCG TTGAGACGCAGACTGTTATGCAAG TAATCCCAGCAGATCCCGGTCAA CTCGACTCACACGAGAGAGTCGT ACCACAAGCAGGGCAAGTATGGT TCCCAGATTCCGCATCCAAGACA GCACAAGCGCTGATGGATTTCAA CCGGGAAGAACTCCCACTTTTCAT TTTAGCTAATTGGAGAGGTTTCTC GGGTGGACAAAGGGATCTCTTTG AAGGGATCCTTCAGGCCGGATCC ACCATTGTCGAAAATCTTAGGACT TATAATCAACCCGTTTTTGTTTATA TACCTATGATGGGGGAGCTTCGA GGAGGAGCATGGGTGGTCGTCGA TAGTCGAATTAATTCCGACCATAT AGAAATGTACGCCGACCAAACAG CTAAAGGAAATGTACTTGAACCCG AAGGAATGATCGAGATTAAGTTCA GAACCAAGGAACTTCTCGAGTGTA TGGGAAGGCTTGATCAACAACTCA TCGGTCTCAAAGAAAAACTAGCCG AAGCCAAGAGCTCTAATTCCTATG GTAAAATCGACCCGCTTCAGCAAC AAATAAAAGCCCGCGAGAAGCAA CTATTGCCTCTATATACTCAGATA GCCACCAAATTTGCCGAGTTGCA CGATACGTCTTTAAGGATGGCTGC CAAAGGAGTCATTAGGGACGTCTT GGAATGGAAAAGCTCGCGTTCTTT CTTTTACAAACGATTATACAGGAG AGTGATGGAAGAATCGCTCGTCA AGACCGTTCGAGATGCTGCAGGT GAACGGTTGACCCATAAGTCGGC TTTGGAGTTGATCCGGAAATGGTT CAATGAGTCCGATATTTCCGGAGA GGCTTCTGATGCTTGGGCTGATG ATGCAGCCTTCTTTAAATGGAAGG ATAATACCGCTAACTACGAGGAGA AGTTGAAAGAGTTGCGCGTTCAG AAGGTATTGGATCAGCTGTCGAAT ATTGGAGATTCGGTAACTAATTTG AGGGCTCTGCCTCAGGGTCTTGC TGCCCTACTTCAAAAGGTGGATCC ATCGAGTCGAGAAGAACTAGTTGA GGAACTCCGAAAAGTGCTCACTT GATTAGCGGCCGTTGATGGTGAA GTGAAACCTTCTTGGTTTCATCAT GGTAGAAATTATTATTAGGCAAAT CTATAATTCTAGTTACATCAATTGT ATTAGACAATAGTATGAACTAATTT ATTTAATTAAATTGTATAAATAGGA AACCTTGAATTCATTTGAATTAATC GGCTTATGCTTGCATTATTTTGTAT TGATTCAATTAATAATTTACATACT TTTGATTATTAATAATGGAAATCCT CAAAGTTTAAGGGGATTGTTTC-
TAAAAAAAAA 21 Amaran- |cD- 1103 GGGGCCATGGTCGTTATTAAAACT thus rudis | NA- CTTCAGTTCTTGCCATCGGTGATT Con- GCCTGCAGCATTGAGAGAAACAA tig CTCATGGTTCAGATCAATCAACTT
CCACTGGCTCTATAGAACCAGTCA TCCATGGAAATATGTTGCACATTG CACTAGTCGGGGTGAATAACCAG ATGAGCTTGTTGCAGGATAGTGGT GATGAAGATCAGGCTCAAGAGAG AATCGATAAGTTGGCCAAAATTCT GAGAGAACAAGAAGTAAGTTCAG CCCTTCGTGCTSGTTGGTETTEGT GTGATTAGTTGCATCATACAGAGA GATGAAGGGCGAACTCCGATGAG GCATTCATTCTATTGGTCAGCAGA AAAACAATATTATAGTGAGGAGCC TTTACTACGTCATTTGGAACCCCC TCTGTCTATGTATCTCGAGCTGGA CAAGCTTAAGGGTTATGAAGATAT CAAATATACTCCTTCCCGTGATCG TCAATGGCATCTTTACACGGTTAT TGATAAACCATTCATTCGGAGGAT GTTTTTGAGAACCCTTGTAAGACA ACCCATCTCCGAGTTCACAGGCG TCGAACTAAGCGCTCTTGAAACAC AAAAGCCTATCTCTTTTACTTCAA GAAGCATCCTAAGGTCCTTAACAA CCGCCATGGAGGAGTTGGAACTC AATGCACATAGTGCTTCACTGAAA CCCGATCACGCTCATATGTACTTG TACATTGTCCGAGAGCAACAAATA TACGATCTTGTGCCATATCACAGG GAGGTGAACATAGATTACCAACAA GAAGAGACTTCGGTTCAATTCTTT TTGGAAGATCTCGCGCATGAAATC CACAGTCTTGCTGGTGTAAGGAT GCATAAACTAAATGTTTGTGAGTG GGAAGTGAAACTTCGGATATCATC TCCCGGGAAAGCTAATGGTTTATG GAGGGTGGCGGTTACAAATGTGA CTGGTCAGACCTGTTCGGTACAT GTTTACCGTGAATTGGAAGATAAC AACCTACATGAAATGGTCTACCAT TCAGTATCCGTTCACGGCCCCCA CCATGGGGTACCTGTGAATGCAC CCTATCAACCACTCGGTGG-
CATCGCCCGTAAGCGAC 22 Amaran- |cD- |541 AGATGCTTTCTTTCTTGCAGTTAC thus rudis | NA- AAATCTTGCTTGTGCAAAGAAACT Con- TCCTCTTATTTATCTGGCTGCAAA
TTCAGGAGCTCGACTTGGTGTTG CCGAAGAGCTAAAATCCTGCTTTA AAGTTGGCTGGTCGGATGAGTCA AACCCCGAGAGTGGATTTCAGTAT GTCTACTTAACCCCGGAAGATTAC GATCGTATCGGATCGTCAGTCATA GCCCACGAGTTAAAACTCGAAAGT GGAGAAAAAAGATGGGTTATAGA CACAGTTGTCGGTAAGGAGGACG GATTAGGTGTCGAGAATTTATCAG GAAGTGGTGCTATAGCAAGTGCA TACTCAAGGGCTTACAAGGAAACA TTTACTCTGACTTTTGTAACCGGT AGAACGGTCGGTATTGGTGCCTA TCTTGCACGTCTTGGGATGCGTTG TATACAGAGGCTTGACCAGCCTAT AATTCTCACGGGTTTTTCTGCGTT AAATAAACTTCTCGGTCGGGAGGT TTACAGTTCACACATGCA- ACTTGGTGGACCGAAGAT-
TATGGGC 23 Amaran- |gD- [1511 TTTTAAGAACGTAATTTCTITTITAT thus rudis | NA- TTATGAGAAGTTGCAGATGATGTT Con- TGTTATAAATGGTCAATCGAAAAA tig CTACCTCTTTGTTATCAGTAACAA
GGGTAAGGTTGTATATATCCGACT CCTCCAAACTCTTCTTCEGGTGGGA GCTACTTAATGTCGCTGGGGCAAT GGAAGTTGTTGTTTGTCGAATTTA AGTGGAGAAGTTTGTTTACATTGA ATTTTAATTAGATGGTATAAGTATG TTATCAAAGATTTATAATTGAAAAC TGGTGTGATAAACAGTTTCAGGAG CAGTGGTCTCATTTTCGAGCAATA CAAAAAGTGCCGTGCTTCTCTAAA CAACGACGATTCAGACATGGCTTC TCATTCCCAAAATAGTGAATACCT GAATGGACCGATGATGCCACTCC TGAGGAATTCATCTGTATTACCCA TTGTGGATAAGTTCTGTTATGCTC TTGGAGGGACGCGGCCAATCCAT AGTATTTTGATAGCAAACAATGGG ATGGCTGCTGTCAAATTTATAAGA AGTATCCGAACATGGGCTTACGA GACTTTTGGTACAGAGAAGGCTAT ATTATTGGTAGCCATGGCTACTCC CGAAGACATGAAAATCAATGCCGA GCATATTCGAATGGCTGACCAGTT TGTTGAAGTCCCCGGAGGGACTA ACAACAATAACTATGCCAATGTGC AGCTCATTGTTGAGGTAATGTATT GTGAGATTAGAAATTTCTAGCCTA TTATCCATAGTTACATGGAACGTG GAACGTAGCCACGTTCCGTGATC CGGGAACATTCATTCCCCAATCAC CACGAAATGCGACCTAAATCGCTC AAGGTGACGTCTCGGTGTAGAAC ACCTTTTTTAAAATGTATTTTGGCC TTCATTTACAAATTAAAGAAAAAAG AAAGGAGGAACAAACGAGATGTA ACCCAGAAACCTAAAAAAGATCCA CTTGAAAATAATTTCTTAAAGCAAA TTAATCATTTTAGTTTAATTITTTITITT CAAATATATATTTTATACGTAATGT ATCTCGTACCCAATCGAACCTGTC GTTCCAGGTAACAATGCTGTTATC TGCTTTATTGTAATTTATTAAATGT GTCCTCTGAAAAAATGGCAATATC CGAGCAACTTGACGCAGTTTTGC CTGGCCAGAGACATGCGTAATTT GTTATATGAGATTACAAATTTATAG CCTTTTATATGGTAAAATCTTGTG GTAGGACTAACTTAAATCCTTTTT CTTTCAGTTAGCGGAAGTTACACG AGTTGACGCAGTTTGGCCTGGTT GGGGACATGCGTCAGAGATCCCC GAGCTGCCAGATTCACTAAGTGC GAAGGGAATTGTGTTTCTAGGGC CCCCAGCTGCATCTATGGCTGCT CTTGGAGATAAAATTGGTTCATCA TTGATTGCACAAGCTGCAGATGTC CCAACTCTTCCATGGAGTGGTTCT CATGTACGTATTACACGTTTTITC CAAATTTTTGATCATTAGAATTT-
TAG 24 Amaran- jgD- 1246 CATACCAATGTCCGAGCATCAAAA thus rudis | NA- ATCGGACACGGGTACGTGAAGCA Con- AAATAAAGAGTCCGAGTAACATAC tig TTATGATTAATGTTAAATAACTTAT
TGTCTTTATTGTCTATATCCAGAAA GCATCGACTAGTAGTGCAGCGAC TGTTTCAGAGTATATAGGCTATCT TGAAAAAGGTCAAATTCCTCCGAA GGTATGCAACATACCAGTGGTTG GCGGGTGTTTAGATTAACTTATTC TATTTATATCAATTATACTTTCAGT GTTCTGCTTTAATTCTGGTTTTATG ATTGCAGCATATATCACTCGTCCA CTATGAAGTTGCTCTAAATATTGA GGGGATGAAATATACTGTATGTTC CATGCCACTCGTACTTTCCTCGTG AATTTTTGTAATGGATGCTATTTTT GACATTATTCTTTCTAAATATGTTT TCCTGATATTAATGAACATGTGGT TTCGGATTGCCAGATTGAGATGAT TAGGGGTGGACCAGGAAGCTACA AAATGTGGTTGAATGGGTCCGTAA TTGAGGCGGAAATACATACTTTAA GAGATGGGGGTCTCTTGATGCAG GTATAACCTGTTTTTTTGGATTITTT TCCGATATACGGTATTTITTATITTTA TATGGACCCTGGATTTGAAAAGCA TTAGATAATGTGCTATCGAACAAG TAGAAGGTAGTTTTGTGAGACCGT GAAGCATTTAGTTAAACCCATTGT TAAGATTACCTTTTAGATTTAGTAC TTCTACAATGCTTGGGATATTAAT CAATAATCATGCTTTTAATAATAAA GAGAAATATTGTCATAGACTCATA GGTATAATGGCTCGTTAAATTATA TGCACTTCTTGTTTATGTGAAGTT CGAGATGCTGTTTGTAATCAACTT TGGAAATCGAGGGCATAGTGCAA AATCTCGGATGTGGTCACCTTTGA TGCAACAATCTCAAAGCCACTTTT GTGGTCAATGTAGATGGTTTCATT TTTATCGTGGTATAAATATGGGTC GCGGTAATCTCAAGAACCCATATA GTAGACGATAACTTGTTATTAAAA GGGATAAGGCTGCATACATCCGA TGTCCCCTTTACCCTGTCTAGATG TGAGCTACTTGGGGGTTTTCCTAT TGAAGTTAAAGATACAAGAAGGAT TTCTGTTAAAAAAAAAGGAATATTT GAACTACAAAAAAGTAATAAGTTT ATATACTAGTTCGTTCTAACCCA-
TATAGCACATTTTAAAAAA Amaran- |gD- 780 TCAGCCTTATCTTGTCAAGGGAAG thus rudis | NA- TGTCAGGATGCTGTGGCACAGAT Con- CAGGCTTCATAGCTTTATGGGAAT tig TTGTGGAGGAGAATATTGACCGAA
CAAATTTTTCTGATGATCTGACTA CAAACAGTGAGCGAAAGTGGGGG GCCATGGTCGTTATTAAAACTCTT CAGTTCTTGCCATCGGTGATTGCT GCAGCATTGAGAGAAACAACTCAT GGTTCAGATCAATCAACTTCCACT GGCTCTATAGAACCAGTCATCCAT GGAAATATGTTGCACATTGCACTA GTCGGGGTGAATAACCAGATGAG CTTGTTGCAGGATAGGTACGTAAG ACTAGCCTGTAACATATGGTTTAA TAGTTTTATTATGTAACCTTGTGCT TTTAATGTCATTTATTTCTAGCCGA TATTACGTAAGACTAGCCGATATT CATCCGATCTTGTAACTGAACCCG ACTTCAAAATCAAATTTAAATTATA TATAAATCAACGTGGACATAAGAC CCGATTTTAATCTGACCCGAAATC AACCCAATGACCCGAATGAACAC CTATAGTTATCACTAACAAGGGTC AGGTTACGTACATCAAACCCCTCA AATCCTGCTTAGGTGGGAGCTTGT CATTGGCATTGGGGTAACGGGAA TGTGTGTGCTATGTACATTGTGCA TCTATTCTTATACTTATGTTGTGAG TTTTTTGGATCGAATATAAAGAGC TTATCTTTTGTATTTTCTTGATGTG CTGTAGTGGTGATGAAGAT-
CAGGCTCAAGAGAGAAT 26 Amaran- |gD- |342 TTGCTTGAACAAACGAAATTGAGT thus rudis | NA- GAGCTCCGTTCGAACATTGCTAGA Con- AACCTCTCTGAGCTAGAAATGTTT tig ACCGAGGATGGCGAAAACATGGA
TACTCCAAAAAGAAAAAGTGCTAT TAATGAACGCATGGAGGCCCTTG TGAGTACTCCTCTAGCTGTTGAAG ATGCCCTTGTTGGTTTGTTTGATC ACAGTGATCATACACTTCAAAGGC GGGTTGTTGAGACCTATGTTCGG AGGCTTTATCAGGTGAATACATAC TTAATTGCGGAGTTAGCTTCAGCT TCACTCAGTCCTATTCGTTGCAAG AACTTCTCTTGATCTTTCTC-
GAGTCGAGGGACT 27 Amaran- |cD- |755 TTCGAGGAGGCGCATGGGTGGTC thus spi- | NA- GTCGATAGTCGAATTAATTCCGAC nosus Con- CATATAGAAATGTACGCCGACCAA tig ACAGCTAAAGGAAATGTGCTTGAA
CCGGAAGGAATGATCGAGATTAA GTTCCGAACCAAGGAACTTCTCGA GTGTATGGGAAGGCTTGATCAAC AACTCATCGGTCTCAAGGAAAAAC TAGCCGAAGCCAAGAGCTCTAATT CCTACAATAAAATTGAGCCCCTGC AGCAACAAATAAAAGCCCGTGAG AAGCAACTATTGCCTCTATATACT CAAATAGCCACCAAATTTGCCGAG TTGCACGATACGTCTTTAAGGATG GCTGCCAAAGGAGTCATTAGGGA CGTCTTGGAATGGAAAAGCTCGC GTTCGTTCTTTTACAAAAGATTATA CAGGAGAGTTATGGAGGAATCGC TCGTCAAGACTGTTCGAGATGCTG CAGGTGAACGGTTGACCCATAAG TCGGCTTTGGAGTTGATCCAAAAA TGGTTCAATGAGTCGAATATTTCC GGAGAGGCTTCCGATGCTTGGGC TGATGATGCGGCCTTCTTTAAGTG GAAGGACAATACCGCCAACTACG AGGAGAAGTTGAAAGAGTTGCGC GTTCAGAAGGTATTGGATCAGCTG TCGAATATTGGAGATTCGGCAACT AATTTGAGGGCTCTGCCTCAGGG TCTTGCTGCCCTACTTCAAAAGGT GGATCCATCGAGTCGAGAAGAAC
TAGTCGAGGAACTCCGAAAAGTG 28 Amaran- |cD- /605 AAGAACGGTCGGTATTGGTGCCT thus spi- | NA- ATCTTGCTCGTCTTGGGATGCGTT nosus Con- GTATACAGAGGCTTGACCAGCCT tig ATAATTCTCACGGGTTTTTCTGCC
TTAAATAAACTTCTCGGCCGGGAG GTTTATAGTTCACACATGCAACTT GGTGGACCGAAGATTATGGGCAC AAACGGGGTAGTTCATCTTACAGT TTCCGATGATCTTGAAGGCATTTC ATCTATCTTGAAGTGGCTGAGCTA CGTTCCACCCTATTCAGGTGGTGA ACTTCCGATTTCTCGGTGTTTAGA CCCTCCAGAAAGACCGGTTGCGT ATTTGCCTGAAAATTCTTGTGATC CTCGTGGTGCTATATCTGGTACG GTTGACTCCACCGGTAAATGGTTT GGGGGTATTTTCGACAAAGATAGT TTTGTGGAAACCTTAGAAGGATGG GCACGAACAGTTGTCACGGGAAG GGCTAAACTCGGAGGAATTCCAG TTGGCATAGTTGCCGTTGAGACG CAGACTGTTATGCAAGTAATCCCA GCAGATCCCGGTCAACTCGACTC ACACGAGAGAGTCGTACCACAAG CAGGGCAAGTATGGTTCCCA-
GATTCCGCATCCAAGACAG 29 Amaran- |cD- |577 GAGGTGAACATAGATCACCAACAA thus spi- | NA- GAAGAGGCTTCAGTTCAATTCTTT nosus Con- TTGGAAGATCTCGCGCATGAAATC tig CATAGTCTTGCTGGTGTAAGGATG
CATAAACTAAATGTTTGTGAGTGG GAAGTGAAACTTCGGGTATCATCT CCCGGGAAAGCTAATGGTTTATG GAGGGTGGCAGTTACTAATGTGA CTGGTCATACCTGTTCGGTACATG TTTATCGTGAATTGGAAGATAGCA ACCTACATGAAATGGTCTACCATT CAGTATCTGTTCACGGCCCCCAC CATGGGGTACCTGTGAATGCACC CTATCAACCACTCGGTGGCATCG CCCGTAAGCGACTTCAGGCCATG AAAAGTAGCACAACTTACTGTTAC GATTTTCCACTGGCTTTCTCAACT GCCCTGAAGCAATCATGGGCATC GGAAGCTCCGGATGTCAAGAAAC CCTCGGACAAAGCGCTTTTGAAA GTAACCGAGCTTGCATTTGCGGAT CCAAAAGGCACATGGGGAACTCC GCTTGTTCCAATAAATCGCAAGCC TGGTATGAACGATGTTGGCATGG-
TAGCCTGGTACA Amaran- |cD- |/1492 GTGCTATTAATGAACGTATGGAGG fe" a ecorreretamereerereere thunber- | Con- TCGAAGATGCCCTTGTTGGTTTGT gii tig TTGATCATAGTGATCATACACTTC
AGAGGCGGGTTGTTGAGACCTAT GTTCGGAGGCTTTATCAGCCTTAT CTTGTCAAGGGAAGTGTCAGGAT GCTGTGGCACAGATCAGGCTTCA TAGCTTTATGGGAATTTGTTGAGG AGAATATTGACCGAACGAATTTTT CTGATCTGACTACAAACAGTGGGA ACCATAGTGAGCGAAAGTGGGGGÇ GCCATGGTCGTTATTAAAACTCOTT CAGTTCTTGCCATCGGTAATTGCT GCAGCATTGAGAGAAACAACTCAT AGTTCCGATCAATCAACTTCCACT GGCTCTATAGAATCAGTCATCCAT GGAAATATGCTGCACATTGCACTA GTGGGGGTGAATAACCAGATGAG CTTGTTGCAGGATAGTGGTGATGA AGATCAGGCTCAAGAGAGAATCG ATAAGTTGGCCAAAATTCTGAGAG AACAAGAAGTGAGTTCAGCCCTTC GTGCTGTTGGTGTTGGTGTGATTA GTTGCATCATACAGAGAGATGAAG GGCGAACTCCGATGAGGCATTCA TTCTATTGGTCAGCAGAAAAACAA TATTATAGTGAGGAACCTTTACTA CGTCATTTGGAACCCCCTCTATCOT ATGTATCTCGAGCTGGACAAGCTT AAGGGTTATGAAGATATCAAATAT ACTCCTTCCCGTGATCGTCAATGG CATCTTTACACGGTTATTGATAAA CCATTCATTCGGAGGATGTTTITTG AGAACCCTTGTAAGACAACCCATC TCCGAGTTCACTGGCGTCGAACT AAGCGCTCTTGAAACACAAAAGCC TATCTCTTTTACTTCAAGAAGCATC CTAAGGTCATTAACAACCGCCATG GAGGAGTTGGAGCTCAATGCACA TAGTGCTTCACTGAAACCCGATCA CGCTCATATGTACTTGTACATTGT CCGAGAGCAACAAATATACGATCT TGTGCCATATCACAGGGAGGTGA ACATAGATTACCAACAAGAAGAGG CTTCGGTTCAATTCTTTTTGGAAG ATCTCGCGCATGAAATCCATAGTC TTGCTGGTGTAAGGATGCATAAAC TAAATGTTTGTGAGTGGGAAGTGA AACTTCGGATATCATCTCCCGGGA AAGCTAATGGTTTATGGAGGGTG GCAGTTACTAATGTGACTGGTCAT ACCTGTTCGGTACATGTTTATCGT GAATTGGAAGATAGCAACCTACAT GAAATGGTCTACCATTCAGTATCT GTTCACGGCCCCCACCATGGGGST ACCTGTGAATGCACCCTATCAACC ACTCGGTGGCATCTCCCGTAAGC GACTTCAGGCCATGAAGAGTAGC ACAACATACTGTTACGATTTTCCA CTGGCTTTCTCAACTGCCCTGAAG CAATCATGGGCATCGGA-
AGCTCCGGATGTCAAGAA- O a 31 Amaran- jcD- 1214 GATGGGTTATAGACACCGTTGTC thus NA- GGTAAGGAGGACGGATTAGGTGT thunber- | Con- CGAGAATCTATCAGGAAGTGGTG gii tig CTATAGCCAGTGCATACTCAAGG
GCTTACAAGGAAACATTTACTCTG ACTTTTGTAACCGGTAGAACGGTC GGTATTGGTGCCTATCTTGCTCGT CTTGGGATGCGTTGTATACAGAG GCTTGACCAGCCTATAATTCTCAC GGGTTTTCTGCGTTAAATAAACTT CTCGGTCGGGAGGTTTACAGTTC ACACATGCAACTTGGTGGACCGA AGATAATGGGCACAAACGGGGTA GTTCATCTTACAGTTTCCGATGAT CTTGAAGGCATTTCATCTATCTTG AAGTGGCTGAGCTATGTTCCACAC TATTCAGGTGGTGAACTTCCGATT TCTCGGTGTTTAGACCCTCCCGAA AGACCGGTTGCGTATTTGCCTGAA AATTGTTGTGATCCTCGTGGGGCT ATATCTGGTACGGTTGACTCCGCC GGTAAATGGTTTGGGGGTATTTTC GACAAGGATAGTTTTGTGGAAACC TTAGAAGGATGGGCACGAACAGT TGTCACGGGAAGGGCTAAACTCG GAGGAATTCCAGTTGGCATAGTTG CTGTTGAGACGCAGACTGTTATGC AAGTAATCCCAGCAGATCCCGGT CAACTCGACTCACATGAGAGAGT CGTACCACAAGCAGGGCAAGTAT GGTTCCCAGATTCCGCATCCAAG ACAGCACAAGCGCTGATGGATTT CAACCGGGAAGAACTCCCACTTTT CATTTTAGCTAATTGGAGAGGTTT CTCGGGTGGACAAAGGGATCTCT TTGAAGGGATCCTTCAGGCTGGA TCCACCATAGTCGAAAATCTTAGG ACTTATAATCAACCCGTTTITGTITTT ATATCCCTATGATGGGGGAGCTTC GAGGAGGCGCATGGGTGGTCGTC GATAGTCGAATTAATTCCGACCAT ATAGAAATGTACGCCGACCAAACA GCTAAAGGAAATGTGCTTGAACC GGAAGGAATGATCGAGATTAAGTT CCGAACCAAGGAACTTCTCGAGT GTATGGGAAGGCTTGACCAACAA CTCATCGGTCTCAAGGAAAAACTA GCCGAAGCCAAGAGCTCTAATTC CTACGATAAAATCGAGCCCCTGCA GCAACAAATAAAAGCCCGCGAGA AGCAACTATTGCCTCTTTATACT-
CAGATAGCCACCA 32 Amaran- |cD- /1121 TAAGAGATGGGGGTCTCTTGATG thus NA- CAGTTGGATGGAAACAGCCATGT thunber- | Con- GATATATGCAGAGGAAGAAGCTG gii tig CAGGAACTCGCCTTCTGATTGATG
GAAGAACTTGTTTGCTTCAGAACG ATCACGATCCTTCAAAGCTGATTG CGGAGACACCGTGTAAGCTTATG CGGTATTTGGTACCAGATAACAGT CACATAGATGCAGATACTCCGTAT GCTGAAGTTGAGGTCATGAAGAT GTGTATGCCTTTGCTTTCCCCTGC ATCCGGTGTTTTACAATTTAAGAT GTCCGAAGGTCAAGCTATGCAGG CTGGTGAACTCATAGCTAGTCTAG AGTTGGATGATCCTTCAGCTGTAA GAAAAGCCGAACCTTTCCGTGGA AGCTTTCCTGTCATGGGCGCACC AACTGCAATATCTGGAAAAGTTCA TCAGAGGTGTGCCGCAAGTTTAAA TGCCACTCGGATGATTTTGGCTG GTTATGAACACAATATAGATGAAG TAGTACAGAGTTTGCTGGAATGCC TTGATAGTCCCGAACTTCCATTCC TTCAATGGCAAGAATGCTTGTCTG TGCTGGCAACACGACTTCCCAAA GATCTGAGATACGAATTGGAATCA AAATCTAGAGCTTTTGAAGGGATT ACCAACACCCAGAACGTAGAATTT CCTGCTAAGTTGTTGAAAAGCATT CTTGAGGACCATTTAAACTCATGC CACGAGAAAGATAAAGGAGCTCA AGAGAGGCTTATTGAGCCTCTTAT GGCTCTTGCAAAGTCTTACGAAG GTGGGCGAGAAAGTCATGCTCGT TTTATTGTTCAATCTTTATTTGAAG AGTATTTATCCGTTGAAGAATTGT TTAGCGACAATCTCCAGGCTGATG TGATTGAACGTCTCCGCCTTCAGT ATAAGAAGGATCTGCTGAAGATTG TTGACATTGTACTGTCGCATCAGG GTGTTAAGAATAAAAATAAGCTGA TTCTACGACTCATGGAACAGCTGG TTTACCCAAATCCCGCTGCATACA GGGGGAAACTTATCCGTTTCTCTC AATTGAACCATACAATGTATTCTG AGTTGGCACTAAAGGCCAGTCAAT TGCTTGAACAAACGAAATTGAGT-
GAGCTC 33 Amaran- |cD- |5705 AGGCACAGTCGGTGAAACCTAAA thus viri- | NA- GGTCATTGTATTGCTGCGCGTGT dis Con- GACAAGTGAGGATCCCGATGACG tig GTTTTAAGCCTACAAGCGGGAAA
GTACAGGAGCTGAGTTTTAAAAGT AAACCGAATGTGTGGGCCTACTTC TCTGTTAAGTCTGGGGGAGGCAT TCATGAGTTCTCGGATTCTCAATT TGGCCATGTTTTTGCATTTGGTGA AAACCGAGGTTTGGCCATAGCAA ATATGATTCTTGGATTAAAAGAAAT TCAAATTCGTGGAGAAATTCGAAC TAATGTTGATTACACCATCGATCT TTTAAATTGTTTGGATTATAGAGAA AACCAAATTCATACAGGTTGGTTG GATAGTAGAATTGCGATGAGGGT CAGAGCCGAAAGGCCACCTTGGT ACATCTCTGTTGTGGGAGGAGGEG CTTTACAAAGCATCGACTAGTAGT GCAGCGACTGTTTCAGAGTATATA GGCTATCTTGAAAAAGGTCAAATT CCTCCGAAGCATATATCACTCGTC CACTATGAAGTTGCTCTAAATATC GAGGGGATGAAATATACCATTGA GATGATTAGGGGTGGACCAGGAA GCTACAAAATGTGGTTGAATGGGT CCGTAGTTGAGGCGGAAATACAT ACTTTAAGAGATGGGGGTCTCTTG ATGCAGTTGGATGGAAACAGCCA TGTGATATATGCTGAGGAAGAAGC TGCAGGAACTCGCCTTCTGATTGA TGGAAGAACTTGTTTGCTTCAGAA CGATCACGATCCTTCAAAGCTGAT TGCGGAGACACCGTGTAAGCTTA TGCGGTATTTGGTACCAGATAACA GTCACATAGATGCAGATACTCCGT ATGCTGAAGTTGAGGTCATGAAGA TGTGTATGCCTTTGCTTTCCCCTG CATCCGGTGTTTTACAATTTAAGA TGTCCGAAGGTCAAGCTATGCAG GCTGGTGAGCTCATAGCTAGTCTA GAGTTGGATGATCCTTCAGCTGTA AGAAAAGCCGAACCTTTCCGTGG AAGCTTTCCTGTCATGGGCGCAC CAACTGCAATATCTGGAAAAGTTC ATCAGAGGTGTGCCGCAAGTTTAA ATGCCACTCGGATGATTTTGGCTG GTTATGAACACAATATAGATGAAG TAGTACAGAGTTTGCTGGAATGCC TTGATAGTCCCGAACTTCCATTCC TTCAATGGCAAGAATGCTTGTCTG TGCTGGCAACACGACTTCCCAAA GATCTGAGATACGAATTGGAATCA AAATCTAGAGCTTTTGAAGGGATT ACCAACACCCAGAACGTAGAATTT CCTGCTAAGTTGTTGAAAAGCATT CTTGAGGACCATTTAAACTCATGC CACGAGAAAGATAAAGGAGCTCA AGAGAGGCTTATTGAGCCTCTTAT GGCTCTTGTAAAGTCTTACGAAGG TGGGCGAGAAAGTCATGCTCGTT TTATTGTTCAATCTTTATTTGAAGA GTATTTATCCGTTGAAGAATTGTTT AGCGACAATCTCCAGGCTGATGT GATTGAACGTCTCCGTCTTCAGTA TAAGAAGGATCTGCTGAAGATTGT TGACATTGTACTGTCGCATCAGGG TGTTAAGAATAAAATAAGCTGATT CTACGACTCATGGAACAGCTGGTT TACCCAAATCCCGCTGCATACAG GGGGCAAACTTATCCGTTTCTCTC AATTGAACCATACAATGTATTCTG AGTTGGCACTAAAGGCCAGTCAAT TGCTTGAACAAACGAAATTGAGTG AGCTCCGTTCGAACATTGCTAGAA ACCTCTCTGAGCTAGAAATGTTTA CCGAGGATGGCGAAAACATGGAT ACTCCAAAAAGAAAAAGTGCTATT AATGAACGTATGGAGGCGCTTGT GAGTACTCCTCTAGCTGTCGAAGA TGCCCTTGTTGGTTTGTTTGATCA TAGTGATCATACACTTCAGAGGCG GGTTGTTGAGACCTATGTTCGGA GGCTTTATCAGCCTTATCTTGTCA AGGGAAGTGTCAGGATGCTGTGG CACAGATCAGGCTTCATAGCTTTA TGGGAATTTGTTGAGGAGAATATT GACCGAACAAATTTTTCTGATCTG ACTACAAACAGTGGGAACCATAGT GAGCGAAAGTGGGGGGCCATGGT CGTTATTAAAACTCTTCAGTTCTTG CCATCGGTAATTGCTGCAGCATTG AGAGAAACAACTCATAGTTCCGAT CAATCAACTTCCACTGGCTCTATA GAATCAGTCATCCATGGAAATATG CTGCACATTGCACTAGTGGGGGT GAATAACCAGATGAGCTTGTTGCA GGATAGTGGTGATGAAGATCAGG CTCAAGAGAGAATCGATAAGTTGG CCAAAATTCTGAGAGAACAAGAAG TGAGTTCAGCCCTTCGTGCTGTTG GTGTTGGTGTGATTAGTTGCATCA TACAGAGAGATGAAGGGCGAACT CCGATGAGGCATTCATTCTATTGG TCAGCAGAAAAACAATATTATAGT GAGGAACCTTTACTACGTCATTTG GAACCCCCTCTATCTATGTATCOTE GAGCTGGACAAGCTTAAGGGTTA TGAAGATATCAAATATACTCCTTC CCGTGATCGTCAATGGCATCTTTA CACGGTTATTGATAAACCATTCAT TCGGAGGATGTTTTTGAGAACCCT TGTAAGACAACCCATCTCCGAGTT CACTGGCGTCGAACTAAGCGCTC TTGAAACACAAAAGCCTATCTCTT TTACTTCAAGAAGCATCCTAAGGT CATTAACAACCGCCATGGAGGAG TTGGAGCTCAATGCACATAGTGCT TCACTGAAACCCGATCACGCTCAT ATGTACTTGTACATTGTCCGAGAG CAACAAATATACGATCTTGTGCCA TATCACAGGGAGGTGAACATAGAT TACCAACAAGAAGAGGCTTCGGTT CAATTCTTTTTGGAAGATCTCGCG CATGAAATCCATAGTCTTGCTGGT GTAAGGATGCATAAACTAAATGTT TGTGAGTGGGAAGTGAAACTTCG GATATCATCTCCCGGGAAAGCTAA TGGTTTATGGAGGGTGGCAGTTA CTAATGTGACTGGTCATACCTGTT CGGTACATGTTTATCGTGAATTGG AAGATAGCAACCTACATGAAATGG TCTACCATTCAGTATCTGTTCACG GCCCCCACCATGGGGTACCTGTGE AATGCACCCTATCAACCACTCGGT GGCATCTCCCGTAAGCGACTTCA GGCCATGAAGAGTAGCACAACAT ACTGTTACGATTTTCCACTGGCTT TCTCAACTGCCCTGAAGCAATCAT GGGCATCGGAAGCTCCGGATGTC AAGAAACCCTCGGACAAAGCACTT TTGAAAGTAACCGAGCTAGCATTT GCTGATCCAAAAGGCACATGGGG AACTCCGCTTGTTCCAATAAATCG CAAGCCTGGTATGAACGATGTTG GCATGGTAGCCTGGTACTTGGAA ATGTCCACCCCCGAGTTCCCTAAC GGAAGAACAATAATGGTTGTAGCT AATGATGTTACCTTCAAGGCCGGA TCTTTCGGACCACGAGAAGATGCT TTCTTCCTTGCTGTTACAAATCTTG CTTGCGCGAAGAAACTTCCTCTTA TTTATCTGGCTGCCAATTCAGGAG CTCGACTTGGTGTTGCCGAAGAG CTAAAATCCTGCTTTAAAGTTGGC TGGTCGGATGAGTCAAACCCCGA GAGTGGATTTCAGTATGTCTACTT AACCCCTGAAGATTACGATCGTAT AGGATCGTCAGTCATAGCCCACG AGTTAAAACTCGAAAGTGGAGAAA AAAGATGGGTTATAGACACCGTTG TCGGTAAGGAGGACGGATTAGGT GTCGAGAATCTATCAGGAAGTGG TGCTATAGCCAGTGCATACTCAAG GGCTTACAAGGAAACATTTACTCT GACTTTTGTAACCGGTAGAACGGT CGGTATTGGTGCCTATCTTGCTCG TCTTGGGATGCGTTGTATACAGAG GCTTGACCAGCCTATAATTCTCAC GGGTTTTTCTGCGTTAAATAAACT TCTCGGTCGGGAGGTTTACAGTT CACACATGCAACTTGGTGGACCG AAGATAATGGGCACAAACGGGGT AGTTCATCTTACAGTTTCCGATGA TCTTGAAGGCATTTCATCTATCOTT GAAGTGGCTGAGCTATGTTCCAC CCTATTCAGGTGGTGAACTTCCGA TTTCTCGGTGTTTAGACCCTCCCOG AAAGACCGGTTGCGTATTTGCCTG AAAATTGTTGTGATCCTCGTGGGG CTATATCTGGTACGGTTGACTCCG CCGGTAAATGGTTTGGGGGTATTT TCGACAAGGATAGTTTTGTGGAAA CCTTAGAAGGATGGGCACGAACA GTTGTCACGGGAAGGGCTAAACT CGGAGGAATTCCAGTTGGCATAG TTGCTGTTGAGACGCAGACTGTTA TGCAAGTAATCCCAGCAGATCCC GGTCAACTCGACTCACATGAGAG AGTCGTACCACAAGCAGGGCAAG TATGGTTCCCAGATTCCGCATCCA AGACAGCACAAGCGCTGATGGAT TTCAACCGGGAAGAACTCCCACTT TTCATTTTAGCTAATTGGAGAGGT TTCTCGGGTGGACAAAGGGATCT CTTTGAAGGGATCCTTCAGGCTG GATCCACCATAGTCGAAAATCTTA GGACTTATAATCAACCCGTTTITTG TTTATATCCCTATGATGGGGGAGC TTCGAGGAGGCGCATGGGTEGGTC GTCGATAGTCGAATTAATTCCGAC CATATAGAAATGTACGCCGACCAA ACAGCTAAAGGAAATGTGCTTGAA CCGGAAGGAATGATCGAGATTAA GTTCCGAACCAAGGAACTTCTCGA GTGTATGGGAAGGCTTGACCAAC AACTCATCGGTCTCAAGGAAAAAC TAGCCGAAGCCAAGAGCTCTAATT CCTACGATAAAATCGAGCCCCTG CAGCAACAAATAAAAGCCCGCGA GAAGCAACTATTGCCTCTTTATAC TCAGATAGCCACCAAATTTGCCGA GTTGCATGATACGTCTTTAAGGAT GGCTGCCAAAGGAGTCATTAGGG ACGTCTTGGAATGGAAAAGCTCG CGTTCGTTCTTTTACAAAAGATTAT ACAGGAGAGTTATGGAGGAATCA CTCGTCAAGACTGTTCGAGATGCT GCAGGTGAACGGTTGACCCATAA GTCGGCTTTGGAGTTGATCCGGA AATGGTTCAATGAGTCAGATATTT CCGGAGAGGCTTCCGATGCTTGG GCTGATGATGCGACCTTCTTTAAG TGGAAGGACAATACCGCTAACTAC GAGGAGAAGTTGAAAGAGTTGCG GGTTCAGAAGGTATTGGATCAGCT GTCGAATATTGGAGATTCGGTAAC TAATTTGAGGGCTCTGCCTCAGG GTCTTGCTGCCCTACTTCAAAAGG TGGATCCATCGAGTCGAGAAGAA CTAGTCGAGGAACTCCGAAAAGT GCTCACTTGATTTCGCAACCGTTG ATGGTGAAGTGAAACCTTCTTGGT TTCATCATGGTAGAAAATATTATTA GGCAAATCTATAATTTTAGTGACA TCAATTGTTTTAGACAATAGTATTG AACTAATTTATTTAATTAAATTGTA TAAATAGGAGACCTTGAATTCATT TGAATTAAGTGGCTTATGCTTGCA TTATTTGTATTGAATCAAATAAT-
TATTTACATAC 34 Ambrosia |cD- 2186 CAGTTGGAATGGGAATTCCACTTT trifida NA- GGCAAATACCAGAAATTAGACGGT Con- TTTATGGGATGGATAATAGTGGAG tig GTTATGATGCTTGGAGAAAAACAT
CGGCTCTTGCAACCCCTTTTGACT TTGACCAAGCAGAGTCAATTAGAC CAAGGGGTCATTGTATTGCTGTTC GTGTAACGAGTGAGGATCCAGAT GATGGTTTTAAGCCACCGGTGGA AAAGTACAGGAACTAGTTTTAAAA GCAAGCCAAATGTGTGGGCATAC TTTTCTGTCAAGTCTGGAGGAGGC ATTCATGAATTTTCGGATTCCCAA TTTGGTCATGTTTTTGCATTTGGA GAGTCAAGAACGTTGGCTATTGCA AATATGGTTCTTGGGCTGAAGGAA ATCCAAATTCGTGGAGAAATTCGT ACTAATGTTGATTATACAATCGAT CTATTACATGCTCTGGATTATAGA GAAAACAAAATCCATACAGGTTGG TTAGATAGCCGAATTGCTATGCGG GTTAGAGCAGAAAGGCCCCCATG GTACCTTTCAGTAGTTGGTGGAGC TCTTTATAAAGCTGCTGCTAGAAG TGCTTTACATGGTTTCTGACTATG TTGGTTATCTTGAAAAGGGTCAAA TCCCTCCTAAGCATATATCATTGG TCAACTCTCAAGTTTCTTTGAATAT TGAGGGTAGTAAGATACACGATTG ATATGCTGAAAAGAGGACCAGGA AGTTACAGACTGAGAATGAATCAA TCTGAAATTGAAGCAGAAATACAT ACTCTACGTGATGGGGGTTTACTG ATGCAGTTGGATGGAAATAGTCAT ATTATATACGCAGAGGAAGAAGCA GCTGGTACTCGTCTTCTAATTGAT GGACGAACTTGCTTGCTTCAGAAT GATCATGATCCTTCCAAATTGGTG GCGGAAACACCATGCAAGCTTCT AAGATATTTAGTCTCAGATGGTAG CCATGTTGATGCTGACACACCTTA TGTTGAGGTTGAAGTGATGAAAAT GTGTATGCCACTTCTTTCGCCGGC TTCTGGAGTTATACAATTTAAAATG TCCGAAGGTCAAGCCATGCAGGC TGGTGAGCTTATAGCAAGACTAGA TCTTGATGATCCGTCAGCTGTAAG AAAAGCAGAGCCCTTTCCTGGAA GCTTTCCTGTTCTGGGCCCACCOG ACCGCCATTTCAGATAAAGTTCAT CTGAAATGTGCTGCAACTCTGAAT GCTGCTCGGATGATTCTTGCTGG CTATGATGACAACATTGATGATGT TGTACAAAATCTGCTTCTTTGTCT GGATAGCCCGGAGCTTCCTTTCC TACAATGGCAAGAATGCTTCGCAG TATTAGCAAATCGACTTGATAAAG ATCTAAGAAACAAGCTAGAATCAA AGTTTAAGGAGTACGAAGGAATTT CCACTCAACAAGCTATCGACTTCC CCGCCAAAGTTTTACGGAACATTC TAGAAACTCACCTCGGATCTTGCT CAGAAAAAGAGAAGGTGGCCCAG GAAAGACTCATTGAACCGTTAATG AGTCTCGTTAAGTCATATGACGGT GGTAGAGAGAGTCATGCACGCGG GATTGTTCATGCTCTTTTTGAAGA GTATTTATCTGTTGAAGAATTATTT AGTGACAATATTCAGGCTGATGTA ATCGAACGTCTACGACTCCAATAC AACAAAGATCTCTTGAGGATTGTT GACATTGTGCTTTCCCATCAGGGA GTTAGGAGTAAAAACAAGCTGATA CTACGACTGATGGAGCATTTGGTC TACCCTAATCCAGCTCCTTATAGA GAGAAACTCATACGGTTTTCTGCA CTCAACCACACAAGTTATTCTGAG TTAGCATTGAAGGCAAGTCAATTG CTGGAACAAACTAAATTAAGTGAA CTTCGTTCAAGTATTGCAAGAAGT CTATCTGAATTAGAAATGTTTACC GAAGAAGGTGAGAATATCGATAC CCCTAAAAGAAAAAGTGCAATTAA CGAAAGAATGGAGGATATCGTGA GTGCTCCTTTGGCGGTTGAAGAT GCCCTTGTTGGTCTTTTTGACCAT AGTGATCACACCCTTCAAAGGCGT GTTGTTGAGACCTATGTTAGAAGA TTATATCAGCCATATCTGGTGAAG GGGAGTGTTAGAATGCAATGGCA CAGATTGGGACTTATTGCAT-
CATGGCAATTCGTGGAAGGG Ambrosia |cD- 1838 TAATCCTGAAGATTACAGTCGAAT trifida NA- CAAATCGTCAGTGATTGCACATGA Con- ATTTTGTCTGGAGAGTGGTGAAAC tig CAGATGGATTATTGATACAATTGT
AGGAAAGGAAGACGGATTAGGGG TTGAGAATTTAAGCGGTAGCGGG GCCATTGCTGGTGCGTTTTCGAAA GCATATAAAGAAACGTTCACCTTA ACATATGTGACGGGAAGAACCGT TGGGATAGGAGCTTATTTGGCCC GTTTGGGAATGAGGTGCATACAA CGGACCGACCAACCAATAATCTTG ACCGGGTTTTCGGCCCTGAACAA GCTTTTGGGCCGAGAGGTTTACA GCTCGCAAATGCAACTTGGAGGG CCGAAGATCATGGGGACAAACGG TGTTGTTCATTTAACGGTTTCTGA CGATCTGGAAGGCGTTATGGCAA TCATAAATTGGTTGAGCTTTGTTC CACCGTATGTTGGTGGCCCGCTT CCTGTTTTGGCAGCAGTGGACCOC GGTAGACCGGCCTGTGGAGTACC AGCCTGAAAACTCGTGTGATCCTC GTGCGGCTGTTTGTGGTACAGTG GATGGGAATGGGAAATGGTTAGG AGGGATTTTCGATAGAGACAGTTT TGTGGAAACATTGGAGGGTTGGG CTAGGACGGTTGTAACGGGCCGG GCCAAACTTGGTGGGATCCCCGT AGGGGTTATTGCTGTCGAGACGC AAACAGTGATGCAAATAATACCTG CGGATCCTGGGCAGCTCGACTCA CACGAACGTGTTGTCCCGCAAGC TGGGCAGGTGTGGTTCCCTGATT CTGCTAGCAAAACTGCTCAAGCTT TAATGGATTTTAACCGCGAAGAGC TTCCGCTGTTCATCATGGCGAACT GGCGGGGGTTTTCTGCTGGTCAA CGGGATCTTTTTGAAGGAATTTTA CAGGCGGGATCGACAATTGTTGA GAACCTTAGAACGTATAAACAGCC GGTTTTCGTTTACATCCCGAAAAC CGGCGAGCTTCGTGGCGGCGCG TGGGTGGTTGTTGACAGTCGAAT CAACTCGGACCATATAGAAATGTA TGCAGAAACAACCGCAAAAGGAA ATGTTCTTGAACCCGAAGGTATGA TTGAAATTAAGTTCCGAAACAAGG AATTGTTAGAATGTATGAACCGAC TGGACCCGCAAATCCGAAACCTC AAACAAAAATTACAAGAAACAAAA TACGACCAAACAATCACCGACCA GATAAAAGCCCGTGAGAAGCAAC TTCTGCCCATTTACACTCAGATCG CCACCAAGTTCGCGGAGCTTCAC GACACATCTTTCCGAATGGCTGAA AAAGGCGTGGTGAAAAAGGTTGT TGACTGGAACATTTCTCGGTTTTT CTTCTACAAAAGGCTCCGCCGTC GGCTCGCAGAAGCTTCTTTAATAA ATACCACACGTGATGCCGCCGGT GACACACTTACCTACAATGCTGCT TATGATATGATCAAGAAATGGTTT TTGGCCACGAAGACGGAAGAAGT TTGGCTTGATGATGATGTGTTITTT CACATGGAAAGATGACCCGTCTAA TTACACCGATAAGTTAGCCACATT ACGTACACAGAAGGTTTCGAATCA GCTATTAAAGTTTGGTGGTTCACC GTCTGATCTGGAAGCTTTACCGCA GGGGCTTGCTGCACTTCTGCAAG AGGTGGATCCAGCGACTAAAAGT AAACTAATTGAAGACATCCGGCGT GTCATTGAGACTTGGCCGGCTAA ATGAGAAGCCATTCGGGCAATGT ATACTATTTAGAACTACTACATGTA AGAATATTTATTTTCCTTGAATATT TTTGTAAATAAATCACACATTTC-
CAATC 36 Ambrosia |cD- /818 GCAGATTATTCCTGCAGATCCTGG trifida NA- GCAACTTGATTCACATGAACGGGT Con- GGTCCCACAAGCTGGGCAGGTGT tig GGTTCCCGGACTCTGCTAGTAAAA
CGGCTCAAGCTATAATGGATTTTA ACCGAGAAGAGCTCCCTCTTTTCA TTATGGCCAACTGGCGGGGGTTT TCAGCGGGTCAACGTGACCTTTITT GAAGGGATTTTACAGGCGGGATC CACAATTGTTGAGAATCTGAGAAC GTATAAACAGCCGTTTTCGTTTAC ATTCCAAAAACCGGTGAACTTCGT GGTGGTGCATGGGTGGTTGTGGA TAGTCGGATCAATTCAGACCATAT TGAAATGTATGCAGAAACCACTGC CAGAGGAAATGTTCTTGAACCCAA GGAATGATTGAAATCAAATTCCGA AATAAAGAATTGTTGGACTGCATG AGCCGACTCGATCCACAAATCCAA ATTCTTAAAGGAAAACTTAAAGAG TCCAAATACGATCAAAGAATCGGC GACCAGATAAAAGCCCGTGAGAG ACAGCTTTTACCAATATACACTCA GATCGCCACGAAATTCGCTGAGC TTCATGACACATCGTTCCGAATGG CTGAAAAAGGGGTGGTAAAAGAA GTGGTTGACTGGAAAGCTTCTCG GTTTTTCTTCTACAAAAGGCTGCG GCGTAGGCTGGGGGAGGCTTCTT TGATAAGTAGCATGCGTGATGCTG CGGGTGGGACGCTGTCGTACAAG TCGGCTTATGATATGATTAAGAAA TGGTTTCTGGAGAGCAAAGGGGA AGCAGAGTTGTGGGTTGATGAT-
GATGCTTTTTTCACA 37 Ambrosia |cD- /505 TTGATTGCTCNGTTTGGCAGTGGA trifida NA- AGCATGTCAGAAGCTCAAAGACT Con- GCCTTTAAATGGAAGCAGCTTAAA tig CTACAACATTTCCTTGAGGTCTTC
TGCAGCTAGATCTGCTGCCATTGA TGAGTTTTGTTATGCACTTGGTGG AAATAGGCCCATTCATAATATTCOTT GTTGCAAACAATGGAATGGCTGCT GTTAAGTTTATAACAAGTGTCAGA ACATGGAGCTACGAAACATTTGGT TCAGAAAAAGCTATTTCATTGGTC GCCATGGCTACTCCAGAAGATAT GAGGATAAATGCAGAGCATATTAG AATCGCTGATCAGTTTGTTGAAGT CCCTGGTGGTACAAATAATAATAA TTATGCTAATGTGCAACTCATTGT AGAGACTGCTGAGATAACACATGT CGATGCGGTTTGGCCTGGTTGGGÇ GTCCATGCATCTGAAATCCCTGAA CTACCAGATGCATTGGAGGCTAAA GGAATTATATTTCTTGGGC-
[E [1 Jesse — 38 Ambrosia |gD- 4795 AAATACCATTTCTTACATTATGAG trifida NA- GCAAATAAAAAAAAATATCAGTTA Con- CTTCTAAAAGTTCATTTCATTAAAT tig AAACAAATTATCAAACAGCGTTCT
TACGTTGGTCATTTTCTGTGCATA ATGTTCTTTTTGCTTGCTATTITTAT AAAGTGGAACTGATTGTTATAAAT AGCTGTTATATTTTACTTTCTATGA GATGCATACATATGATATTTITTAGT GTTTTGAAATCGTAAATATGATTTT ATGAAATGTTGAGGTTTTGGAAGG ATTATAAGACTTGCCCAAAGGTTT GTTTTCATTATCTAACATATTGACT TGAATTGCACTTTTGTAGGAGCTT AGTTTCAAAAGCAAGCCAAATGTG TGGGCATACTTTTCTGTCAAGGTA AATTTATATTTACATATTTTGATGC AATTTCCCAATTCAAAAATATAAAT ATATTTTTATTTAAAAATTGCAGTC CGGAGGAGGCATTCATGAATTCT CAGATTCTCAATTTGGTAAGAAAA CTGAATCTTGTTTGGTTTTAGTTTT TAACAGTCATACTGCTGGTGTAGT TGGCTTTACACGATTCTTTGCTAA AGCATTCGTTATCTTATTTAATTAT TATTTTGTACGCTTTAGGTCATGTT TTTGCATTTGGAGAGTCAAGAGCA CTGGCCATTGCAAATATGGTTCTT GGGTTGAAAGAAATCCAAATTCGT GGTGAAATCCGTACTAATGTTGAT TATACAATCGACTTATTACATGTG AGCATCTTGGTTCTTTTGCTCCCT TTGTTCCAAATTTTATTGCCTACAA AAAGTACTCCATAATTTAAGAAAT GCACAAGCAAATCAGATTTTAATC AGCAGAGTGCCAGTTTACCCTGA ATGCATCTAAAATACGGTAAAATT TTAAGATAAGTGTAATCAAGGGTG AAACTAGAAAACTAATAAATTACAA CATTTCATTTCTAGAACAGGACAG TTATTATGATACAAATTAAAAAAGA AAAGTAGACAAATTTTGAGACGGG TCGACTGTCATGAAGTTAATAGAT TACATACGTTTTTTTTACAGAATTA CTTATGTACATGCTTCATATTGAG AAATTGATTAAATTTACAAATTCTT TATTTCTTGTACATTAGCTTTATGA TTTTGATTCTTTTACACTTAATAAT TTTATTATTATTATTTCTACATTTGT AGGCTCCGGATTATAGCGAAAAC AAAATCCATACAGGTTGGTTAGAT AGCCGAATTGCTATGCGGGTTAG AGCAGAAAGGCCCCCATGGTACC TTTCAGTAGTTGGTGGAGCTCTTT ATGTAAGTGGTTTGTTAATAATACT TTTCCTTTTCTATATTCACCACCOGT TTAATGTACTCTTGTCTTACTGTTG ATTTTTGTTGACCTCAGAAAGCTG CTGCTAGAAGTGCAGCCATGGTA TCAGATTATGTTGGTTATCTTGAA AAGGGTCAAATCCCTCCTAAGGTA TTTTGACTTAGCATTGACCTTTATG TTGACCTCAGAATGCCCTTTGCTT AATTTTITTITTCTTITCTTGAAGCA TATATCATTGGTCAACTCTCAAGT TTCTTTGAATATTGAGGGTAGTAA GTACACGGTAAGTAATAACATAAA TTTCTGTTCTTGATCTCTGTTTITT TTTAATTATTATTTTTCTTCTAATTT ATGTGTTTGTTTTTTGTAAGATTGA TATGGTAAAAAAAGGACCAGGAA GTTACAGATTAAAAATGAATCACT CTGAGATTGAAGCAGAAATACATA CTCTACGCGATGGGGGTTTGTTAA TGCAGGTAAACATTTTTGTTTATTT TTCAAGTTAAAGTCCTATGGGTAT GGGATACATGATTTGCTTCATAAA TAAAATCAAAAGATACAATATTTAC AGTCATGCAAATTTGTTACATTITT ACATGTATTTACACATTTGTTTGTC ACATGCCTATATTTATATAATATTG ATTGGATAATTTAATATTGTAGTTG GATGGAAATAGCCATATTATATAT GCAGAGGAAGAAGCTGCCGGTAC TCGACTCCTAATTGATGGACGAAC TTGCTTGCTTCAGGTGTCAACAAC TACTTCTTITTTGTTGTTGTTTACTT CTTTITTGTTGTTGTTGTTATTATTA TTATTATTTATTATAGATGTGGCTG TTTCTATGCATTTACTTTTGAGTTG ATTGATTTAGGTCATATGTTATCTT TAATGGGTAAAAAAGTTTAGCCTA AAACGAGACGGGTCAGTTGGATC CATTAGGTTGAAAGTCACCTGTAG TTTATCTATTACGCATAATGTGATT AGACCACCTGATTGCATTAAAAAA AATATAAAACCCTCATTTCAATCCA AACGGACTCGTTTAGACAATCTTC CATTTTTGACCAATACCCGCCCAT TATCCCACATCTGTTTGTTATTCAC TAATTTGTTCTATATTTGGTTTAAT TTGTTGTTAGAATGATCATGATCC TTCCAAGTTGATGGCAGAAACGC CATGCAAGCTTCTAAGATACTTAG TGTCTGATGGTAGCCATGTTGATG CTGACACACCTTATGTTGAGGTTG AAGTGATGAAAATGTGTATGCCAC TTCTTTCGCCGGCTTCTGGAGTTA TACAATTTAAAATGTCCGAAGGTC AAGCCATGCAGGTTAGATTTAAAT ATCTTCTTAATATTTATTGTITITG CGAAATATATACAAAAATTTCCTTT TACGAACATTAATGAAAAATCAATT CTGAATCTACATGAGAATTTAATTT ATTTATTTTTTTATATATGGACATC TTTTCTGAGTAAAATTTTGGCATTG TAGTTGTTTTTTCTTTATTTTATAA CTCTAACTTTTTCAAAAAGGTAATA TCTAAGATATTTAGAGGCATAATG AGTCACTTTTTACAATTAATATTAT TCCCAATTGTTTCAGTTACAAATAT TATATTGGTACGTCAGTGCTCGAT TTTTTGTTGTTTACACAAATTCTCT CCATAATACAATCATATCTITATCT TCTATACAGCATGCATACATGGGA TGCACTTTTTGTCCTAAATTTTGAA CATATGAATGTTTTTATATGTAGG CTGGTGAGCTTATAGCAAGACTAG ATCTTGATGATCCGTCAGCTGTAA GAAAAGCAGAGCCCTTTCCTGGA AGCTTTCCTGTTCTGGGCCCACC GACCGCCATTTCAGATAAAGTTCA TCTGAAATGTGCTGCAACTCTGAA TGCTGCTCGGATGATTCTTGCTGG CTATGATGACAACATTGATGAAGT AATCTTGTTTTTATTTTATTCOITITT GCCATTTAAATAACCCATATGAAA TATTTTAATCAACTAATCACAACTT TATGTAGTGGTGAAAAATTTAACC CACAATTTATGAACGGGTCGACTT GGGTTATGTTGATCCATAAGTGGT CAAACACAAAAATAGAAATGCTCA AAAGATAATGGTCATATGGGTCAA GTCAGCCAAAGTGTATTCTTATGC ATAAAACCTCCTAAATCATTTTTAT TCAAAAAAATTAACTTCTTTTAATA ATATAAATTTTGGAATAGTATTTGA TATGCTAATTATATATAACTAAATT TAGTTTTTGAACAAGTGTTAAGGG TCAAGCAAGCCTAACTTGCTTTGA TTGACACAAAATTATGCATTATTCC ATACCGGTTTTGACTCGTGACCCA TCCCGCCAAGTCGTTCOTTTITTTCOT CACCATTAGCTTAGTTCTTCAATG AGCTTACTTTCTTTTAAATTITTCOT TTTTGTTATTTATAACATGTTTAAT CTTTGATTTTAGGTTGTGCAAAAC CTGCTTCTTTGTCTGGATAGTCCT GAGCTTCCTTTCCTTCAATGGCAA GAATGCTTTGCAGTTCTAGCAAAT CGACTTCCTAAAGATCTAAGAAAC AAGGCAAATTAATGTCTTATAATC ATGTTGTTTATTTAAGTTATTATTG TAACATTTTTTTTCTAATTTITTAATT CTTCTATAACAGTTGGAGTCGAAG TTTAAGGAGTACGAAGGAATTTCC ACCCAACAAGCTATCGAATTCCCC GCCAAAGTGTTACGGGCCATTCTA GAAGTTAGTTTACGATCAAATACT TATAATTTGACTTTTTTCGTATITTA AATATTTAGTTTACTTTATACTATA CTTTTGTAATGTTTATGGTTAGAC GCACCTTGGATCTTGCTTAGAAAA AGAGAAAGTTGCCCAAGAAAGAC TCATTGAACCGTTGATGAGTCTTG TTAAGTCATATGAAGGTGGCAGAG AGAGTCATGCACGTGGGATTGTT CATGCACTTTTTGAAAAATATTTAT CCATTGAAGAATTATTTAGTGACA ATATTCAGGTGAAGTTTTTAACTG ATTAGTATAAAAAATGCAAAATTTC ATATATAAACTTTATAGTATCATAT TTATTTTTTCAAATTTCCATGGTGA AACAAATAACGAATGCAAAAGCAA TGTTATTACTGTGAATCATGTCTA CACATAATGCTCTTATAAGTAATTA ATTTGCATGCACTTTAACATCATA CTCTTTCATGTTGAGTAAATTTITC TTAAATGTAAAATGAAATTITTITTC TTTAGGCTGATGTAATCGAACGTC TACGACTCCAATACAACAAAGATC TCTTGAGGATTGTTGACATTGTGC TTTCCCATCAGGTATATATGTTATT TTTAGAGGTTGCAAAATGGACTGT GGGATGGGTTTGTCAACGGGTCA AAATTTGCCATTTTGCTAAGGGTT GA-
TACCGGTTGGGTTGGGTTGGGETT 39 Ambrosia |gD- 4587 TTTTCAAAAAAAAAAAATTAAAAAA trifida NA- AAAAATAGTGTCTACTTCTITTITITTG Con- TATTAAATTTATTTGCACATAACTC tig TTTTATAAAGCAAGTCATGTTTGTA
CATTTTAACTTCAAAGACTCATGA CACGAAAATAAAACGAATAAGTTA AATTTGTTTACATAATATTGTGCTA CATTTACATATATACTTGTTATCCA ATAGTTAATTATGATGATTTACATT TTTAATTATTTGTGTTCAAAGTTTG TTTAAACTCACTGGATAATCTTGG GAGTTAAGGCAAGTATGGCATTGA AAAGTAGAACCCTGGGCCCTGAA ACAGCGATTGAAAAAAAGCAGTG GCGATGGGTCGAACTGGTCAATT CAAAGGGTCCCTTTATCAGCAAAT TACTTGGACAATTTTGACTTTTACT TTGACCTCTTCCAATAATATAGCTT TTTITTTATTCCTTCTAATTTTAACTA CAAATATACATGTTTGTTTTTCTAC ACACTTTCAACATCTGTACATTTCT ATCAGTTTGTCTACAGTATATAATC GCAAGAATATTTCGACTTATAATC ATAGATATTCTGTTTGCACTTATAG CATGCAAAATACAGATGCATAGAA TTTGCATACGCCTAAAAGTGCAGA GAAAAATCATGTGAACATTCTTAT GTCCGTTTTATAAATGTTGCTCAC AAATAGACAAAAATATTACTGTTTT TTTGTTATACTATGTAGAAAAAGTC ATGCAAATCACATACATATGGATT GTTTTATAACAATTACAAATTGTGT GCAGGAGAGTTGACGTAGATTCT GGGACCGAAGAGGGTGTGGTTGA GGCACTTTTGGTGAAGTTGGCTC GTGAGATACACACAATGGTTGGTA TAAAAATGCACCGGTTAGGTGTTT TTGAGTGGGAGGTTAAGCTTCGC ATGGTGTCTTCTGGTCAAGCCAAT GGTGCCTGGAGGGTEGTEGTÇACÇ TAATGTGACCGGTCATACGTGTAT TGTACATGTAAGTTAAAAGGCCAT TTTAGACATTTCAACAATAGGTAA ACTCTTTTTGCTCATACATGCTTAA TGTTACTCTTTGCGATTTTCATTTA GGTCTATCGGGAAATCGAGGATA ATGTTGAACACAAGGTAGTTTATC ATGCTACCTCGACATCAAGCCCCT TACATGGTGTATCTGTGAACACAC CATTTCAGCCTTTGAAATTACTCG ATCAGAAACGTCTTTTGGCCCGTA AAAGCAATACTACTTACTGCTATG ACTTTGCACTGGTAAAATTGCCAT TTTGCCCTTCTACTTTTAATGCATG CATGTTCTTTTATTTAAMAAGTAGTA AAATTACCATTCTGCCCTTTCGAA CTTGGATTATGGTTAATTCTTACG GATCTTGCTTTTGTATCCGCAGGC ATTTGAAGCAGCCCTTGAGAATAT CTGGTCATTGAAACTCCCAGGTGT CAACAAGCCCGTTGGTAAGCTTGT AAATGTGACAGAGCTCGCATTTGC TGACCCGAGAGGCTCATGGGGTA CACCGCTTGTGCAAATAAACCGTG AGCCGGGCCAGAACAATGCGGGC ATGGTGGCTTGGACCATGGACCT CTGCACACCTGAGTTTCCTCATGG AAGGACAATTTTGGTAGTTGCAAA CGATGTCACGTTTAAAAATGGGTC TTTCGGCCCGATTGAGGACGCGT TTTTCGAGGCGGTCACCGAACTT GCCTGTTCCAAGAAACTGCCACTC ATTTACCTGGCAGCGAACTCGGG GGCCCGAATTGGGGCGGCTGAG GAGGTTAGATCTTGCTTTAGAATT GGGTGGTCCGATGAATCGAACCC TGATTCAGGGTTCCAGTATTTGTA CCTAACTCCTGAAGATTACAGTCG AATCAAATCGTCAGTGATTGCACA TGAATTTTGTTTGGAGAGTGGTGA AACCAGATGGATTATTGATACAAT TGTAGGAAAGGAAGACGGATTAG GGGTTGAGAATTTAAGCGGTAGC GGGGCCATTGCTGGTGCGTTTTC GAAAGCATATAAAGAAACGTTCAC CTTAACATATGTGACGGGAAGAAC CGTTGGGATAGGAGCTTATTTGG CCCGTTTGGGAATGAGGTGCATA CAACGGACCGACCAACCAATAAT CTTGACCGGGTTTTCGGCCCTGA ACAAGCTTTTGGGCCGAGAGGTT TACAGCTCGCAAATGCAACTTGGA GGGCCGAAGATCATGGGGACAAA CGGTGTTGTTCATTTAACGGTTTC TGACGATCTGGAAGGCGTTATGG CAATCATAAATTGGTTGAGCTTTG TTCCACCGTATGTTGGTGGCCCG CTTCCTGTTTTGGCAGCAGTGGAC CCGGTAGACCGGCCTGTGGAGTA CCAGCCTGAAAACTCGTGTGATC CTCGTGCGGCTETTTGTGGTACA GTGGATGGGAATGGGAAATGGTT AGGAGGGATTTTCGATAGAGACA GTTTTGTGGAAACATTGGAGGGTT GGGCTAGGACGGTTGTAACGGGC CGGGCCAAACTTGGTGGGATCCC CGTAGGGGTTATTGCTGTCGAGA CGCAAACAGTGATGCAAATAATAC CTGCGGATCCTGGGCAGCTCGAC TCACACGAACGTGTTGTCCCGCA AGCTGGGCAGGTGTGGTTCCCTG ATTCTGCTAGCAAAACTGCTCAAG CTTTAATGGATTTTAACCGCGAAG AGCTTCCGCTGTTCATCATGGCGA ACTGGCGGGGGTTTTCTGCTGGT CAACGGGATCTTTTTGAAGGAATT TTACAGGCGGGATCGACAATTGTT GAGAACCTTAGAACGTATAAACAG CCGGTTTTCGTTTACATCCCGAAA ACCGGCGAGCTTCGTGGCGGCGÇ CGTGGGTGGTTGTTGACAGTCGA ATCAACTCGGACCATATAGAAATG TATGCAGAAACAACCGCAAAAGG AAATGTTCTTGAACCTGAAGGTAT GATTGAAATTAAGTTCCGAAACAA AGAATTGTTAGAATGTATGAACCG ACTGGACCCGCAAATCCGAAACC TCAAACAAAAATTACAAGAAACAA AATACGACCAAACAATCACCGACC AGATAAAAGCCCGTGAGAAGCAA CTTCTGCCCATTTACACTCAGATC GCCACCAAGTTCGCGGAGCTTCA CGACACATCTTTCCGAATGGCTGA AAAAGGGGTGGTAAAAGAAGAAG TGGTGGTTGACTGGAAAGCTTCTT CTCGGTTTTTCTTCTACAAAAGGC TGCGGCGTAGGCTGGGGGAGGC TTCTTTGATAAGTAGCATGCGTGA TGCTGCTGGTGACACGCTTACCTA CAATGCTGCTTATGATATGATCAA GAAATGGTTTTTGGAGAGCAAAG GGGAAGCAGAGTTGTGGGTTGAT GATGATGCTTTTTTCACATGGAAA GATGACCCGTCTAATTACACTGAT AAGTTAGCCACATTACGTACACAG AAGATATCAAATCAGTTATTAAAG ATTGGTGGTTCACCGTCCGATCTG GAAGCTTTACCGCAGGGGCTTGC TGCACTTCTGCAAGAGGTAACTGT TGTTTCTTGAATCTTGACGACTAC ATTCCTTTCACCATTTTGCAAGTC GAGAATAAGATTGTTTTTAATGTC GTTTTGTTTGTTGTGTTTCAGGTG GATCCAGCGACTAAAAGTAAACTA ATTGAAGACATCCGGCGTGTCATT GAGACTTGGCCGGCTAAATGAGA AGCCATTCGGGCAATGTATACTAT TTAGAACTACTACATGTAAGAATA TTTATTTTCCTTGAATATTTTTGTA AATAAATCACACATTTCGAATCATA TCAAATAATTATTCATTGTAGTCTT TTCTGTAATCGGTATTTGCGATAT CTATGTTTGAGTATTTATTAACTAA TTATACAAATCTTTGTTGGGCTTT GCACTTTCTGGATCAACAACTCAG ACCTCGTGATCAAGCTTTGGTGAA CATGAATGAACTGCATCTGCAACA GTGAGAAAAATCTTGTTTTCCCCA ATCAAGTCGGGGAAACCTGATGC GTATAGCTTGTCTAGCACTTGTTG ACCCGGGTTCGCAAGAATAAGCT GTCAAACCAAAATATTATTGTTTTA GCACGCAATTGCGGAAATTATTAT GAAAACTTTTTATCCGTTGTTAAC CGTATAATAAATGAGTTGATGATA TGTGTAGTAGTGTTTAATCGCATA AAATTACATGTTTTGTTCTCAACTG GTTTTGGCACGTTTACTTGTAATA TTATAAACAGTATTGCTGCTGCTT ACTTGGACATCTCTCTTTTGCAGA CTACGGTATAACTCTTCCAAGGCA TGGATTCCACTTGTGTCGATATCA GTAACCGCTGCAGTTAGAGAACA CTCTTTAMACAAAGTATTCGCCCC GCTCATTAAATATTCATGACTGAC TATAGGAAATAGAAGAGCTTCTTT CTTACGTGACAATTCCACTATCAA GAACTGAATTTTGGGTTGAAAAGT TGCTGCTTTTAGATTATCTTCTTCC TCAGCTAGCCATCTTAATATCCTG CAACGAATTATAGCTTTCAAGGAT
GGAAACATACATACATACATAGT- A Cr AA 40 Ambrosia |gD- 2723 ATGGGGACAAACGGTGTTGTTCAT trifida NA- TTAACGGTTTCTGACGATCTGGAA Con- GGCGTTATGGCAATCATAAATTGG tig TTGAGCTTTGTTCCACCGTATGTT
GGTGGCCCGCTTCCTGTTTTGGC AGCAGTGGACCCGGTAGACCGGC CTGTGGAGTACCAGCCTGAAAAC TCGTGTGATCCTCGTGCGGCTET TTGTGGTACAGTGGATGGGAATG GGAAATGGTTAGGAGGGATTTTC GATAGAGACAGTTTTGTGGAAACA TTGGAGGGTTGGGCTAGGACGGT TGTAACGGGCCGGGCCAAACTTG GTGGGATCCCCGTAGGGGTTATT GCTGTCGAGACGCAAACAGTGAT GCAAATAATACCTGCGGATCCTG GGCAGCTCGACTCACACGAACGT GTTGTCCCGCAAGCTGGGCAGGT GTGGTTCCCTGATTCTGCTAGCAA AACTGCTCAAGCTTTAATGGATTT TAACCGCGAAGAGCTTCCGCTGT TCATCATGGCGAACTGGCGGGGCGÇ TTTTCTGCTGGTCAACGGGATCTT TTTGAAGGAATTTTACAGGCGGGA TCGACAATTGTTGAGAACCTTAGA ACGTATAAACAGCCGGTTTTCGTT TACATCCCGAAAACCGGCGAGCT TCGTGGCGGCGCESTEGGETEGTTGÇE TTGACAGTCGAATCAACTCGGACC ATATAGAAATGTATGCAGAAACAA CCGCAAAAGGAAATGTTCTTGAAC CCGAAGGTATGATTGAAATTAAGT TCCGAAACAAGGAATTGTTAGAAT GTATGAACCGACTGGACCCGCAA ATCCGAAACCTCAAACAAAAATTA CAAGAAACAAAATACGACCAAACA ATCACCGACCAGATAAAAGCCCG TGAGAAGCAACTTCTGCCCATTTA CACTCAGATCGCCACCAAGTTCG CGGAGCTTCACGACACATCTTTCC GAATGGCTGAAAAAGGCGTGGTG AAAAAGGTTGTTGACTGGAACATT TCTCGGTTTTTCTTCTACAAAAGG CTGCGGCGEGTAGGCTEGGGGAGGÇ CTTCTTTGATAAGTAGCATGCGTG ATGCTGCGGGTGGGACGCTETCG TACAAGTCGGCTTATGATATGATT AAGAAATGGTTTCTGGAGAGCAAA GGGGAAGCAGAGTTGTGGGTTGA TGATGATGCTTTTTTCACATGGAA AGATGAACCAAAGAACTACAGGC ACAAGTTAAGTGAGTTACGTGCAC GCAAGGTTGCAAATGAGTTATTAA AGATTGGTGGTTCAGCGTCGGAT GTGGAAGCGTTGGCGCAGGGGCT GGCTGCACTTCTAAAAGAGGTAAC TGTTGTTTCTTGAATCTTGACGAC TACATTCCTTTCACCATTTTGCAA GTCGAGAATAAGATTGTTTTTAAT GTCGTTTTGTTTGTTGTGTTTCAG GTGGATCCAGCGACTAAAAGTAAA CTAATTGAAGACATCCGGCGTGTC ATTGAGACTTGGCCGGCTAAATGA GAAGCCATTCGGGCAATGTATACT ATTTAGAACTACTACATGTAAGAA TATTTATTTTCCTTGAATATTITTITG TAAATAAATCACACATTTCCAATCA TATCAAATAATTATTCATTGTAGTC TTTTCTGTAATCGGTATTTGCGAT ATCTATGTTTGAGTATTTGTGAAC CTTTTATTAACTAATTATACAAATC TTTGTTGGGCTTTGCACTTTCTGG ATCAACAACTCAGACCTCGTGATC AAGCTTTGGTGAACATGAATGAAC TGCATCTGCAACAGTGAGAAAAAT CTTGTTTTCCCCAATCAAGTCGGG GAAACCTGATGCGTATAGCTTGTC TAGCACTTGTTGACCCGGGTTCG CAAGAATAAGCTGTCAAACCAAAA TATTATTGTTTTAGCACGCAATTG CGGAAATTATTATGAAAACTTTTTA TCCGTTGTTAACGTATAATAAATG AGTTGATGATATGTGTAGTAGTGT TTAATCGCATAAAATTACATGTTTT GTTCTCAACTGGTTTTGGCACGTT TACTTGTAATATTATAAACAGTATT GCTGCTGCTTACTTGGACATCTCT CTTTTGCAGACTACGGTATAACTC TTCCAAGGCATGGATTCCACTTGT GTCGATATCAGTAACCGCTGCAGT TAGAGAACACTCTTTAAACAAAGT ATTCGCCCCGCTCATTAAATATAG GAAATAGAAGAGCTTCTTTCTTAC GTGACAATTCCACTATCAAGAACT GAATTTTGGGTTGAAAAGTTGCTG CTTTTAGATTATCTTCTTCCTCAGC TAGCCATCTTAATATCCTGCAACG AATTATAGCTTTCAAGGATGGAAA CCTACATACACACATAGTTAAAAT CCGATGGTTTGTACCTTTCTTTGA TGTAATTTGAATTTGAGAAATAAAT AGCAGAATCAATCCTAACAATTAC AACACCCGGAATTTTATTCGCTTC TGGATACTGTCCGATATTCCGGTA CACGCTGGTCATCGGAATCTTCC CAAGAAGCGCGGTTCGTGGGCGT GTAACTTGCAGAAGAATCTTAGCA AAAGATATCGCCACCTGATTCAAC AATCTTATTAAACAAAAGCTCAAAA TTGACCTAAAAACAATGTTTTCATA ACCAGTTCAATGGTTGGGCCCAA ATGCCATCATAAATAATTTATTTAT TTATATGAATAATATATAAACTATA AAGTAAGTAGTAAATGGATCAC-
TAAATGAT 41 Ambrosia |gD- 2408 GTTGACCTGAAACATGTTTITITGTT trifida NA- TTCAAAAGTTTTAGATAATTTGTTA Con- GTCAAATATGATGAAATATACAAA
TTATTATTTCAATAATAATCCAGTT TTTTTAAAAAGATATAGGTGATATG TGTACAGTAAAAAGATACAATTTG GTAGGTATTTCACAAGTTCAGGCG CTAGAAACATGTCCTTTTAAGATTT TGTTCTGCCTTGTACCTTTTGAAC GTTTAAAGCAGAACCCGACTCGA CCCATTCATGAGTAAATGGGTTGA AATTGCCGTCTCTAGTTTITTCTGG TTTTATGTTTCCACTTATTAATATT AAATAAAATTTATTCTGAAGTCGAT ATTTTAAATTTAACAGGGAGTTAG GAGTAAAAACAAGCTGATACTACG ACTGATGGAGCATTTGGTCTACCC TAATCCAGCTCCTTATAGAGAGAA ACTCATACGGTTTTCTGCACTCAA CCACACAAGTTATTCTGAGGTCAA TATCGTCATTTAACATACTCAAAG GCTCTAACTAACTACTTTITTITITAT TGGCATATTTAACTTCATTATCATT AATTTAACAGTTAGCATTGAAGGC AAGTCAATTGCTGGAACAAACTAA ATTAAGTGAACTTCGTTCAAGTAT TGCAAGAAGTCTATCTGAATTAGA AATGTTTACCGAAGAAGGTGAGAA TATCGATACCCCTAAAAGAAAAAG TGCAATTAACGAAAGAATGGAGGA TATCGTGAGTGCTCCTTTGGCGGT TGAAGATGCCCTTGTTGGTCTTTT TGACCATAGTGATCACACCCTTCA AAGGCGTGTTGTTGAGACCTATGT CAGAAGATTATACCAGGTATGCAG TTGGTTTTTCTCTTAAACATATACT ATCTATCCATTTAAGTCGCCATTG ACTAATACAGCTCAATAAAAAAAG TTAAAAGGATGGATGTGATTAATT TGTAAATATCAAAATCAAGTCTATT GTATATTGATATTTGGTATGATAAA CAAGGGGCAAATGAGTAATTGTAC CTTGTAATTCTATTTTCAGCCATAT CTTGTGAAGGGGAGTGTTAGAAT GCAATGGCACAGATTGGGACTTAT TGCATCATGGCAATTCGTGGAAG GGCATACTGAGGAATTGAATGCTT CTGGACCATTGGTTGATAGGAAAT GGGGAGCTATGGTTATTATTAAAT CTCTTCAATTTTTGCCCGATGTGA TAAGTGCAGCTCTTAAAGAAACGA CTCAAACTGGGTCAGCAGGTCAT ACTATTACTAACCATGGTAACATG ATGCACATTGCATTGGCCGGCAT CAACAACCAAATGAGTTTGCTTCA AGACAGGTTTGACCATACAAGTCA ACATCATCATGTTTGGTTATAAATC AATTTATAAAAATTCATTATCTCTA GAATTGAAACCAAATTATATTTATA TATTTGATATTAACTAATACGCGC ATATTTTCTTATAAACTGCAGTGGT GATGAGGACCAGGCCCAAGAAAG AGTCAATCGGTTAGCAAAAATATT AAAGGACAAAGAACTAAGCTCGA GTCTAAAAAACGCAGGGTATGATG TTATAAGTTGTATAATACAAAGAG ACGAAGGTAGGGGCCCAATGAGA CATTCATTTCATTGGTCAGAAAGT AATCGTTATTATGTCGAAGAGCCA TTATTGCGCCATGTGGAACCTCCA TTATCTATTTACCTTGAACTGGTTT GTACTCATAGCCCGCTTCATTITTG TTTCCATTTCTTTAAATAGTAATAA TACTAAGGACAAATGTCCACAAAA AGTGAAATCGAGTCAGCTTTTAGC ACATTAGGCTTCCACGTTATCGTT TTTACATGATTGGATGCCATGTCA GCAGTTTTAAGCATTTTGTATGCC GTGTCAACTTATGCAACCTAACTC TTTGCAGTAACACACATTAAAGTG TTGCAATAGCGACACATTTTAGAA GAGAAGTAAATTTTATAAATACTCA TAATTTTAGAAGGTTTCGGTAAAA AAGTATTAGTTTCCAGAAAGGTCT AAAATTATTTATGTCACTATATATC TTGGCATTTTTATCCACACTCAGT GACCAGTTTTGTTGTGTTGCTAAA TTTCAATTTTGGTGCAGCGACCCT CTTTTAAAGACTTAGTGAACAACG GGGACATTCGATTACCATTTAATG ACATATTCCCTAATATTAGAAGAA AAGTTATATAAATTTCCATGTATTA TAAATTGGTTATTTTTTCAGGATAA ACTGAAGGGCTATGAGAATATACA GTACACTCCATCGCGCGACAAAC AATGGCACATGTATACGGTTGATG CGAAACCACTTCCGGTTCGCAGA ATGTTTCTTCGAGCACTTGTAAGA CAACCAACAAAAGAATGGTTTTCG
CCCTCGGGATACCATGATTC 42 Ambrosia |gD- |1771 TGGCGGCCGTAAAGTTTATAAGAA trifida NA- GTGTGAGAACATGGAGTTATGAAA Con- CATTTGGTTCAGAAAAAGCAATTT tig TGTTGGTAGCCATGGCGACTCCG
GAGGATATGAGGATAAATGCAGA GCATATTAGAATTGCTGATCAATT TGTGGAAGTCCCAGGTGGTACAA ATAATAATAATTATGCAAACGTGC AACTCATTGTGGAGGTATATAGGT TTCATACATATATAATTTATTTAGG CATCAACTGATGTATTTTATGAAC CACCATACACGCCATTTTATTGCA AAGTAACCATTGTTCTTTAGAACA GTCTTATTTTGACTTTTCGGTCAAA TTATCTGTTTATAAACGTTCATTCC TGCAACGATAAGTCAGATATGATG GTTCAAGAAGTCGGTCACTAAACA AGGGTTGGATTTACCTTCACTTAT TCAGAAGTCCTTAAAATATTACATT TGCTCTCTACAAAGTATTTTTTACT ATGAATTTTCAAGTGGACTACATC AATTTTGTAATTAATACGAAATTAC AAATGTGTGTAACTTTTGATGAAA AATCCTACTTTGACATACCTAACT ATATCCTTAAGTTATAACATTGATA TTGCAATGCTTAACTTTTGAGGAA AATCATTACCTACATCATGTTTAAT GATTGCAGACTGCTGAGATAACAC ATGTTGATGCTGTTTGGCCTGGTT GGGGTCATGCATCTGAAATCCCG GAACTACCAGATGCATTGGAGGC TAAAGGAATTATATTTCTTGGGCC ACCTGCTGCTTCCATGGCAGCTTT AGGAGATAAAATCGGTTCATCGTT GATTGCACTAGCAGCTGATGTGC CAACACTTCCATGGAGTGGCTCTC ATGTAAGTTTTGCCACTTTTATAGT CAGTCCTTTTTAGTTTTTTCAGAAA AAAAAAACTCATTTCATACCTCTTG TTTTTCAAAAAACTGGTTCCTAATG CTACTTATTTTTTAAAAACTGCATC TTTACTAGTCTTTATAACACCTCAT CTTTTTAGCTCGTATTCTTTTACAA TTGCACCTATAAACCTCAAAAATC TCATCTTTATTCTGCTTATTATATA AAATATCCTGCTTTAGGTGAAAAT TCCTGTGGAAAGCTGTTTGGCCA CAATCCCAGATGATGTATATAGAA AAGCTTGTGTATCTACAACTGAAG AAGCAATTGCTAGCTGTCAGTTTA TTGGTTATCCGGCTATGATCAAGG CATCATGGGGCGGAGGTGGCAAA GGCATAAGAAAGGTTTGTTTCCTT CAACTTGACCTTTAAAAGTCAATA AACTAGTTTTGACCTCAAAGCACT TATTTATTTTTGTTAATTTAGGTGC ATAATGATGAAGAAGTCAAGGCAC TTTTCAAGCAAGTTCAAGGTGAAG TGCCAGGTTCACCTATATTCATTA TGAAAGTTGCCTCCCAGGTGAGA AAACGTTTGAATAACTCATCTGAT CTTAATGTGTGACTTAAAACTTATT ATAACACTATTTAAATATTATTTTA AAACCAGAGCCGGCATCTAGAAG TTCAGCTACTGTGTGATCAGCATG GCAATGTAGCAGCCTTACATAGTC GTGATTGCAGTGTTCAAAGACGAC ACCAAAAGGTAGTCTGAGAATCG CAGTCTTTCTAAAAAATAACAAATC TTGATTTTAATATAATTTTITTATATT TTTTTAAGATTATCGAGGAGGGTC CAATTACCGTAGCTCCACCTGACA CAATAAAGAAGCTTGAGCAAG-
CAGCAAGAAGA 43 Ambrosia | gD- 1320 CATGATGAGTGATGACATATGTGG trifida NA- TCTTTCACTCTAATTCTTGCAATTG Con- TCGATGCTTTCGACTCTTGTCTTC tig TTTACGGTAATTAGTCTTCTTCCC
CTTTCCCCCAAATTTAAAAAAGAA ACTAAAGTTTGATAGCTCTGTTTG GCAGTGGAAGCATGTCAGAAGCT CAAAGACTGCCTTTAAATGGAAGC AGCTTAAACTACAACATTTCCTTG AGGTCTTCTGCAGCTAGATCTGCT GCCATTGATGAGTTTTGTTATGCA CTTGGTGGAAATAGGCCCATTCAT AATATTCTTGTTGCAAACAATGGA ATGGCGGCAGTAAAGCTTATAAGA AATGTGAGAACATGGAGGTATGAA ACATTTGGTTCAGAAAAAGCAATT TTGTTGGTAGCCATGGCTACCCC GGAGGATATGAGGATAAATGCAG AGCATATTAGAATTGTTGGTCAAT TTGTAGAAGTGCCTGGTGGAACA AATAATGATAATAATGCAAACGTG CAACTCATTGTAGAGGTATATAGG TTTCATACATATATAATTTATTTAG GCATCAACTGATGTATTTTATGAA CCACCATACACGCCATTTTATTGC AAAGTAACCATTGTTCTTTAGAAC AGTCTTATTTTGACTTTTCGGTCAA ATTATCTGTTTATAAACGTTCATTC CTGCAACGATAAGTCAGATATGAT GGTTCAAGAAGTCGGTCACTAAAC AAGGGTTGGATTTACCTTCACTTA TTCAGAAGTCCTTAAAATATTACAT TTGCTCTCTACAAAGTATTTTTTAC TATGAATTTTCAAGTGGACTACAT CAATTTTGTAATTAATACGAAATTA CAAATGTGTGTAACTTTTGATGAA AAATCCTACTTTGACATACCTAAC TATATCCTTAAGTTATAACATTGAT ATTGCAATGCTTAACTTTTGAGGA AAATCATTACCTACATCATGTTTAA TGATTGCAGACTGCTGAGATAACA CATGTCGATGCGGTTTGGCCTGG TTGGGGTCATGCATCTGAAATCCC TGAACTACCAGACGCATTGGAGG CCAAAGGAATTGTATTTCTTGGCC CCCCTGCTTCATCCATGGCGGCT TTAGGAGATAAAATTGGTTCTTCT TTGATTGCACAAGCGGCTGCTGTA CCAACACTTCCATGGAGTGGTTCT CATGTAAATATTGCCACTTTTATAG TCGGTCCTTTTTAGTTTTTTCAGAA AAAAAAAACTCATTTCATACCTCTT GTTTTTCAAAAAACTGGTTCCTAAT GCTACTTATTTTTTAAAAACTG-
CATCTTTATTTTATTITITIT 44 Conyza |cD- |7026 ATGAATTTTCGGGCATTTGATCTG canaden- | NA- AAGCTCAACATTTTTCTGGGCGAT sis Con- TCAAATAAGCGTTTTACTGTTACA tig AAAAGTTTCGTCTCAACGGGTGAC
CACTACACGACTTCTGATAACACC AATCCGACCAGTCTTACAAAGGTG AAGGTGAAGAAACATGTGAAGAG GGATAAATTTGGAGAAAGAATGGC ATCACTAAAACAGATAGTGTCACC CTATGGCAAGGATTTTGCTAAACA TAGTTGTAAGGGTTATAGTTACAA CACAATAGAATGGAGTCTAGACTT GGACCATTGTGTTTTAGAGAAGAA GGGAATCGAACGCAAAGTTTGCG TTGTGATAGTCAGGAGACAGAAA GGGCAATTTGTTTCTGTTCTITTTTA AGTTAGATAGTGGCACCATGTCAG AAGCTCAAAGAATGCTTCTAAGTG GAAGTTTCAATTATTATGGTAATG GCATTGTAAATGGGGCGATTTCAC TGAGGTCTTCTGCTAGTAGATCTG CAATTGATGAATTTTGTAATGCAC TTGGAGGCACCAGGCCAATCCAA AGTATTTTAATTGCAAATAATGGAA TGGCGGCTGTAAAGTTTATAAGAA GTGTGAGGACATGGAGTTATGAA ACATTTGGCTCAGATAAAGCTATT TTGCTGGTAGCCATGGCTACACC GGAAGATATGAGGATAAATGCCG AGCATATTAGAATCGCTGATCAGT TTGTTGAAGTCCCTGGTGGTACAA ATAATAATAATTATGCGAATGTGC AACTCATTGTAGAGACTGCTGAGA TAACACATGTTGATGCTGTTTGGC CTGSGTTGGGGCCATGCATCCGAA ATCCCTGAGCTGCCTGATGCATTG GAAGCAAAAGGTATTGTATTITTCTT GGGCCACCAGCTTCCTCCATGGC AGCTTTAGGTGATAAAATTGGTTC TTCTTTGATTGCACAAGCTGCTGA TGTACCGACACTTCCTTGGAGCG GTTCTCATGTAAAAATTCCTGTGG ATAGCTGTTTGGACACACTCCCG GATGATGTATATAGAAAAGCGTGT GTGCATACAACAGAAGAAGCAATT GCTAGTTGTCAAGTTGTTGGTTAT CCAGCAATGATTAAGGCATCATGG GGTGGAGGTGGCAAAGGCATAAG AAAGGTGCATAATGACGAAGAAGT CAAGGCACTTTTTAAGCAAGTTCA GGGTGAAGTGCCTGGTTCCCCTA TTTTCATTATGAAAGTTGCTTCTCA GAGCCGACATCTAGAAGTGCAGC TACTATGCGATCAACATGGGAATG TAGCAGCTTTGCATAGTCGTGATT GCAGTGTTCAAAGGCGACATCAA AAGATTATTGAAGAGGGGCCAATA ACCATAGCTCCACATGACACAATA AAGAAGCTTGAGCAAGCGGCGAG AAGATTAGCAAAGTCGGTTAATTA TGTTGGAGCAGCCACTGTAGAGT ATTTGTATAGCATGGAAACTGGAG ACTATTACTTTTTGGAGCTCAATC CCCGGTTACAGGTTGAGCATCCA GTCACAGAGTGGATAGCGGAAAT CAATCTACCTGCAGCACAAGTTGC GGTTGGAATGGGCATTCCTCTTITTG GCAAATACCAGAAATAAGACGATT TTATGGAATGGACAATAGTGGAG GATACGATGCTTGGAGGAGAACA TCTGCTCTTGCAACTCCATTTGAC TTTGACAAGGCAGAGTCTATCAGC CCAAAAGGTCATTGTATTGCTGTA CGTGTAACAAGTGAGGACCCAGA TGATGGATTTAAGCCCACTAGTGG AAAAGTTCAGGAGCTAAGTTTTAA AAGCAAGCCAAATGTCTGGGCAT ACTTTTCTGTCAAGTCCGGAGGAG GCATTCATGAATTCTCAGATTCTC AATTTGGCCACGTTTTTGCATTTG GCGAGTCAAGACCTTTGGCTATTG CAAATATGGTTCTTGGGCTGAAGG AAATTCAAATTCGTGGCGAGATCC GTACGAATGTTGATTATACAATTG ATCTGTTACATGCTCCTGATTATA GAGAAAATAAAATACATACCGGTT GGTTAGATAGCCGAATTGCTATGA GGGTTAGAGCAGAAAGGCCCCCT TGGTATCTTTCAGTAGTTGGGGGA GCACTTTATAAAGCTGCTGCTAGA AGTGCAGCCATGGTCTCGGACTA TGTTGGTTACCTTGAAAAGGGCCA AATCCCTCCTAAGCATATATCATT GGTCAACTCACAAGTTTCTTTGAA TATTGAGGGCAGCAAATACACGAT TGATATGGTAAAAAGAGGGCCAG GAAGTTACAGATTGAGAATGAATC AATCCGAGATTGAAGCAGAGATAC ATACACTACGTGACGGAGGCTTAT TGATGCAGTTGGATGGGAATAGT CATATATTATACGCCGAGGAAGAA GCTGCCGGTACTCGCTTGCTTATT GATGGACGGACTTGCTTGCTTCA GAATGATCATGATCCTTCCAAGTT GATGGCTGAAACACCATGCAAACT TCTAAGGTACTTGGTCTCAGATGA TAGCCATGTTAATGCTGACACACC GTATGCTGAGGTTGAAGTTATGAA GATGTGTATGCCACTCCTTTCACC GGCTGCTGGAGTTATACAATTCAA GATGTCAGAAGGTCAAGCCATGC AGGCTGGTGAGCTTATAGCAAGG CTAGATCTTGACGATCCGTCAGCT GTAAGAAAAGCAGAGCCTTTCAAT GGAAACTTTCCTCTTCTTGGGCCT CCAACGGCCATGTCAGACAAAGT GCATCAGAAGTGTGCTGCAACTTT AAATGCTGCTCGAATGATTCTCGC AGGCTATGATCATAACATTGATGA ATTGGAATCCAAGTTTAAGGAGTA CGAAGGAATTTCCACACAACAAAC TATTGACTTTCCTGCTAGAGTTCT ACGGGTCATTCTTGAAACCCATCT TGGATCTTGCTCAGAAAAAGAAAA GGGAGCCCAAGAAAGGCTCGTTG AGCCATTAATGGGTCTTGTAAAGT CATATGAAGGGGGAAGAGAAAGT CATGCACGTGGGATCGTTCATGC TCTATTTGATGAATATTTATCTGTT GAAGAGTTGTTCAGCGACAACATT CAGGCTGATGTAATCGAACGTCTT CGACAACTATACAAGAAAGATCTC TTGAGGATTGTCGACATTGTCCTT TCCCATCAGGGTGTTAGGAGTAAA AACAAATTGATACTACGGCTGATG GAGCATTTGGTTTACCCCAATCCG GCTGCGTATAGGGAGAAACTGAT ACGATTTTCTCAACTTAACCACAC AAGTTATTCTGAGTTAGCACTGAA GGCAAGTCAACTTTTAGAACAAAC TAAACTAAGTGAACTTCGTTCAAG CATTGCGCGAAGTCTTTCTGAATT AGAGATGTTTACTGAAGAAGGTGA AAATATGGATACCCCTAAGAGGAA GAGTGCCATTAATGAAAGAATGGA GGATATTGTGAGTGCTCCATTGGC AGTTGAAGATGCCCTTGTTGGTCT TTTTGACCATAGCGATCACACCCT TCAAAGGCGTGTTGTTGAGACCTA TGTTCGAAGATTATATCAGCCATA TCTCGTGAAGGGGAGTGTTAGAA TGCAGTGGCACAGATCCGGACTC ATCGCTACATGGCAATTTATAGAA GGACTCATTGGAGAAGTTAATGTG CCTGACTATGAACAGAATGAAGCT CCCTTGGAAGACAAGAAATGGGG AGCTATGGTTATTATTAAATCTCTT CAATTTTTGCCTGATGTCATAAGT GCATCTCTTAAAGAAACGAGTCAT AACCTTCCCAGAACAAGTCAGAAT GGGTTTGCTGGTCATAGTAACCAT GGTAATATGATGCACATTGCTTTG GCCGGCATAAATAACCAGATGAG TTTGCTTCAAGACAGTGGTGATGA GGATCAGGCTCAAGAGAGAGTCA ACAGGTTAGCAAAAATACTCAAAG ATAAAGAAGTAAGCTCGAGTCTTA AAAACGCAGGGTATGGAGTGATC AGTTGTATAATACAAAGAGATGAA GGGAGAGGCCCCATGAGACACTC ATTTCACTGGTCAGAAGAGAATCA TTATTATATTGAAGAGCCATTATTG CGTCACTTGGAGCCTCCATTATCG ACATATCTTGAACTGGACAAACTT AAGGGCTATGATAATATAAAGTAC ACTCCGTCGCGTGACCGTCAATG GCACATGTATACTGTTGATGCTAA ACCACTTCCGGTACAAAGAATGTT TCTTAGAACTCTTATAAGGCATCC AACAAAGGAATGGTTCTCGCCCTC AGGTTACCAAGGTTCAGAAGATGA GGGCCCACGGTCTCAGTTAAATC TCCCTTTTACATCAAGGAGCATCT TGAGATCATTAGTGACGGCTATGG AGGAGTTGGAACTTCATGTTCATA ATGCTACTGTCAAGTCTGACCATG CTCATATGTACCTATATGTATTGAA GGAGCAACAAATTGGTGATCTTGT TCCATACACAACGAGAGTGGATGT AGATTCTGGGACAGAAGATTGCG TGGTTGAGACACTTTTGGTAAGGC TGGCTCGTGAAATCCATTCAATGG TTGGTGTAAAGATGCACCGGTTG GGAGTTTTTGAGTGGGAGGTGAA GCTTTGCATGGCATCATCGGGTC AAGCCAACGGTGCGTGGAGGGTT GTGGTCACAAATGTGACTGGTCAT ACCTGCGTTGTGCATGTATATCGT GAACTGGAAGATACTGGTTTGCAC AAGGTGTATCATGCTACCTCTACA TTGGGTCCTTTGCATGGCGTACCOT GTGAATACACCCTTTCAGCCTTTA GGATTACTTGATCAGAAGCGTCTT TTGGCAAGGAAAAGCAATACTACG TACTGCTACGACTTTGCACTGGCA TTTGAAGCAGCTCTTGAGAATATC TGGGCGTCGAAAGTCGTAAGTGA TAGCAGGCCTAAGGGTAAACTTGT GAATGTGACGGAGCTCATGTTTG CTGAGCCAAGTGGCTCATGGGGA ACTCCCCTTGTTGCAGTAAATCGT GAGCCAGGGCAAAACAAGGTGGG CATGGTGGCGTGGACTATGGACC TCTGCACTCCTGAGTTTCCTGATG GAAGAACGATTTTGGTAGTAGCAA ACGATGTTACGTTCAAAAATGGAT CTTTTGGTCCTCTTGAGGATGCCT TTTTTGAGGCAGTTACTGATCTCG CTTGTGCCAAGAAACTGCCACTAA TATACTTGGCAGCAAACTCGGGG GCCCGTATCEGGAGCGGCTGAGGA AGTCAGATCTTGCTTTAGAATTGG GTGGTCTGATGAGTCGACTCCTG AATCGGGATTCCAGTATTTGTATC TTACTCCTGAAGATTATACCCACA TCAAATCATCTGTAATAGCTCATG AGGTTCATCTATCAAATGGCGAAA CAAGATATGTCATCGATACTATTG TGGGAAAAGAAGACGGACTCGGG GTTGAAAATTTGAGTGGTAGCGG GGCAATTGCTGGTGCCTATTCGAA AGCATATAAGGAAACGTTTACATT AACATATGTTACTGGAAGAACAGT TGGGATAGGCGCATATCTGGCAC GTCTTGGGATGCGGTGCATACAG CGGCTTGATCAACCGATTATATTA ACGGGTTTTTCTGCACTGAACAAG CTTTTGGGCCGAGAGGTTTATAGC TCACAGATGCAACTAGGTGGGCC TAAAATTATGGCTACGAATGGTGT TGTCCATTTAACGGTGTCCGATGA TCTCGAAGGTGTCTCAGCTATCTT GAATTGGTTGAGCTTTGTTCCACC TTATGTCGGTGGCCCACTTCCTGT TTTAGCACCTGTGGATCCACCAGA AAGGCCCGTTGAGTACCTCCCTG AAAACTCATGTGATCCTCGGGCA GCTATTTGTGGGGTCGTGGATAG CAACGGTGAATGGGCTGGTGGGÇGA TTTTCGATAGAGACAGTTTTGTGG AGACATTGGAAGGTTGGGCGAGG ACAGTCGTAACGGGTCGTGCCAA ACTTGGCGGGATCCCAGTCGGGA TCGTTGCTGTTGAGACACAAACAG TGATGCAAGAAATACCTGCAGATC CCGGGCAGCTTGATTCACACGAA CGTGTTGTTCCTCAAGCAGGTCA GGTCTGGTTCCCGGATTCEGCCA GCAAAACAGCTCAGGCATTGATG GATTTCAACCGAGAAGAGCTCCC ACTTTTCATCATGGCTAACTGGCG AGGCTTTTCTGCAGGTCAGCGGG ATCTTTTTGAAGGGATTTTACAAG CAGGGTCAACAATTGTTGAGAATC TCAGAACATATAACCAGCCTGTTT TTGTATACATCCCGAAAACTGGAG AACTTCGTGGCGGTGCATGGGTG GTTGTCGACAGTCGAATCAATTCA GATCATATAGAAATGTATGCAGAA ACCACAGCAAAAGGAAATGTCCTT GAACCTGAAGGTATGATTGAGATT AAGTTCCGAAACAAAGAATTGATA GACTGTATGGGTCGTCTAGATCCA CAGATTCGAAGCCTTAAAGAAAGA CTTCGAGAAACAAAGTACGATCAA ACGATCGTCCAACAGATAAAATCT CGTGAAAAACAGCTTTTACCGATT TACACTCAAATTGCTACCAAATTC GCTGAACTTCATGACACATCATTG CGAATGGCTGAAAAAGGTGTGGT CAAACAAGTTGTTGACTGGAAAGT ATCTCGGTTTTTCTTTTACAAAAG GCTTCGTCEGTAGGCTCGCAGAGG CTTCCTTGATCAGTAGTGCTCGTG AAGCTGCTGGTGATACTCTTTCCT ACAAGTCTGCTCATGAGTTGATTA AGAAATGGTTTTTGGAATCGAAAA CTGAAGATTTATGGCTTAGTGATG ATGCTTTTTTCACTTGGAAAGACA ATCTGATGAACTATAATGACAAGT TAGCCAAGCTACGTACTCAGAAG CTCTTGGATCAGTTATTAAAGATT GGTAATTCACCATTGGATCTACAA GCTTTACCACAAGGCCTCGCCGC ACTTTTGCAAGAGGTGAACAA-
ACTCTCTTTTATTTTCCCTTAG 45 Conyza jcD- /6912 ATGAATTTTCGGGCATTTGATCTG canaden- | NA- AAGCTCAACATTTTTCCGGGCGAT sis Con- TCAAATAAGCGTTTTACTGTTACA tig AAAAGTTTCGTCTCAACGGGTGAC
CACTACACGACTTCTGATAACACC AATCCGACCAGTCTTACAAAGGTG AAGGTGAAGAAACATGTGAAGAG GGATAAATTTGGAGAAAGAATGGC ATCACTAAAACAGATAGTGTCACC CTATGGCAAGGAGTCTAGACTTG GACCATTGTGTTTTAGAGAAGAAG GGAATCGAACGCAAAGTGGCACC ATGTCAGAAGCTCAAAGAATGCTT CTAAGTGGAAGTTTCAATTATTAT GGTAATGGCATTGTAAATGGGGC GATTTCACTGAGGTCTTCTGCTAG TAGATCTGCAATTGATGAATTTTG TAATGCACTTGGAGGCACCAGGC CAATCCAAAGTATTTTAATTGCAAA TAATGGAATGGCGGCTGTAAAGTT TATAAGAAGTGTGAGGACATGGA GTTATGAAACATTTGGCTCAGATA AAGCTATTTTGCTGGTAGCCATGG CTACACCGGAAGATATGAGGATAA ATGCCGAGCATATTAGAATCGCTG ATCAGTTTGTTGAAGTCCCTGGTG GTACAAATAATAATAATTATGCGA ATGTGCAACTCATTGTAGAGACTG CTGAGATAACACATGTTGATGCTG TTTGGCCTGGTTGGGGCCATGCA TCCGAAATCCCTGAGCTGCCTGAT GCATTGGAAGCAAAAGGTATTGTA TTTCTTGGGCCACCAGCTTCCOTCC ATGGCAGCTTTAGGTGATAAAATT GGTTCTTCTTTGATTGCACAAGCT GCTGATGTACCGACACTTCCTTGG AGCGGTTCTCATGTAAAAATTCCT GTGGATAGCTGTTTGGACACACTC CCGGATGATGTATATAGAAAAGCG TGTGTGCATACAACAGAAGAAGCA ATTGCTAGTTGTCAAGTTGTTGGT TATCCAGCAATGATTAAGGCATCA TGGGGTEGGAGGTGGCAAAGGCAT AAGAAAGGTGCATAATGACGAAG AAGTCAAGGCACTTTTTAAGCAAG TTCAGGGTGAAGTGCCTGGTTCC CCTATTTTCATTATGAAAGTTGCTT CTCAGAGCCGACATCTAGAAGTG CAGCTACTATGCGATCAACATGG GAATGTAGCAGCTTTGCATAGTCG TGATTGCAGTGTTCAAAGGCGACA TCAAAAGATTATTGAAGAGGGGCC AATAACCATAGCTCCACATGACAC AATAAAGAAGCTTGAGCAAGCGG CGAGAAGATTAGCAAAGTCGGTTA ATTATGTTGGAGCAGCCACTGTAG AGTATTTGTATAGCATGGAAACTG GAGACTATTACTTTTTGGAGCTCA ATCCCCGGTTACAGGTTGAGCAT CCAGTCACAGAGTGGATAGCGGA AATCAATCTACCTGCAGCACAAGT TGCGGTTGGAATGGGCATTCCTC TTTGGCAAATACCAGAAATAAGAC GATTTTATGGAATGGACAATAGTG GAGGATACGATGCTTGGAGGAGA ACATCTGCTCTTGCAACTCCATTT GACTTTGACAAGGCAGAGTCTATC AGCCCAAAAGGTCATTGTATTGCT GTACGTGTAACAAGTGAGGACCC AGATGATGGATTTAAGCCCACTAG TGGAAAAGTTCAGGAGCTAAGTTT TAAAAGCAAGCCAAATGTCTGGG CATACTTTTCTGTCAAGTCCGGAG GAGGCATTCATGAATTCTCAGATT CTCAATTTGGCCACGTTTTTGCAT TTGGCGAGTCAAGACCTTTGGCTA TTGCAAATATGGTTCTTGGGCTGA AGGAAATTCAAATTCGTGGCGAGA TCCGTACGAATGTTGATTATACAA TTGATCTGTTACATGCTCCTGATT ATAGAGAAAATAAAATACATACCG GTTGGTTAGATAGCCGAATTGCTA TGAGGGTTAGAGCAGAAAGGCCC CCTTGGTATCTTTCAGTAGTTGGG GGAGCACTTTACAAAGCTGCTGCT AGAAGTGCAGCCATGGTCTCGGA CTATGTTGGTTACCTTGAAAAGGG CCAAATCCCTCCTAAGCATATATC ATTGGTCAACTCACAAGTTTCTIT GAATATTGAGGGCAGCAAATACAC GATTGATATGGTAAAAAGAGGGC CAGGAAGTTACAGATTGAGAATGA ATCAATCCGAGATTGAAGCAGAGA TACATACACTACGTGACGGAGGC TTATTGATGCAGTTGGATGGGAAT AGTCATATATTATACGCCGAGGAA GAAGCTGCCGGTACTCGCTTGCT TATTGATGGACGGACTTGCTTGCT TCAGAATGATCATGATCCTTCCAA GTTGATGGCTGAAACACCATGCAA ACTTCTAAGGTACTTGGTCTCAGA TGATAGCCATGTTAATGCTGACAC ACCGTATGCTGAGGTTGAAGTTAT GAAGATGTGTATGCCACTCCTTTC ACCGGCTGCTGGAGTTATACAATT CAAGATGTCAGAAGGTCAAGCCA TGCAGGCTGGTGAGCTTATAGCA AGGCTAGATCTTGACGATCCGTCA GCTGTAAGAAAAGCAGAGCCTTTC AATGGAAACTTTCCTCTTCTTGGG CCTCCAACGGCCATGTCAGACAA AGTGCATCAGAAGTGTGCTGCAA CTTTAAATGCTGCTCGAATGATTC TCGCAGGCTATGATCATAACATTG ATGAATTGGAATCCAAGTTTAAGG AGTACGAAGGAATTTCCACACAAC AAACTATTGACTTTCCTGCTAGAG TTCTACGGGTCATTCTTGAAACCC ATCTTGGATCTTGCTCAGAAAAAG AAAAGGGAGCCCAAGAAAGGCTC GTTGAGCCATTAATGGGTCTTGTA AAGTCGTATGAAGGGGGAAGAGA AAGTCATGCACGTGGGATCGTTC ATGCTCTATTTGATGAATATTTATC TGTTGAAGAGTTGTTCAGCGACAA CATTCAGGCTGATGTAATCGAACG TCTTCGACAACTATACAAGAAAGA TCTCTTGAGGATTGTCGACATTGT CCTTTCCCATCAGGGTGTTAGGA GTAAAAACAAATTGATACTACGGC TGATGGAGCATTTGGTTTACCCCA ATCCGGCTGCGTATAGGGAGAAA CTGATACGATTTTCTCAACTTAAC CACACAAGTTATTCTGAGTTAGCA CTGAAGGCAAGTCAACTTTTAGAA CAAACTAAACTAAGTGAACTTCGT TCAAGCATTGCGCGAAGTCTTTCT GAATTAGAGATGTTTACTGAAGAA GGTGAAAATATGGATACCCCTAAG AGGAAGAGTGCCATTAATGAAAGA ATGGAGGATATTGTGAGTGCTCCA TTGGCAGTTGAAGATGCCCTTGTT GGTCTTTTTGACCATAGCGATCAC ACCCTTCAAAGGCGTGTTGTTGAG ACCTATGTTCGAAGATTATATCAG CCATATCTCGTGAAGGGGAGTGT TAGAATGCAGTGGCACAGATCCG GACTCATCGCTACATGGCAATTTA TAGAAGGACTCATTGGAGAAGTTA ATGTGCCTGACTATGAACAGAATG AAGCTCCCTTGGAAGACAAGAAAT GGGGAGCTATGGTTATTATTAAAT CTCTTCAATTTTTGCCTGATGTCAT AAGTGCATCTCTTAAAGAAACGAG TCATAACCTTCCCAGAACAAGTCA GAATGGGTTTGCTGGTCATAGTAA CCATGGTAATATGATGCACATTGC TTTGGCCGGCATAAATAACCAGAT GAGTTTGCTTCAAGACAGTGGTGA TGAGGATCAGGCTCAAGAGAGAG TCAACAGGTTAGCAAAAATACTCA AAGATAAAGAAGTAAGCTCGAGTC TTAAAAACGCAGGGTATGGAGTG ATCAGTTGTATAATACAAAGAGAT GAAGGGAGAGGCCCCATGAGACA CTCATTTCACTGGTCAGAAGAGAA TCATTATTATATTGAAGAGCCATTA TTGCGTCACTTGGAGCCTCCATTA TCGACATATCTTGAACTGGACAAA CTTAAGGGCTATGATAATATAAAG TACACTCCGTCGCGTGACCGTCA ATGGCACATGTATACTGTTGATGC TAAACCACTTCCGGTACAAAGAAT GTTTCTTAGAACTCTTATAAGGCA TCCAACAAAGGAATGGTTCTCGCC CTCAGGTTACCAAGGTTCAGAAGA TGAGGGCCCACGGTCTCAGTTAA ATCTCCCTTTTACATCAAGGAGCA TCTTGAGATCATTAGTGACGGCTA TGGAGGAGTTGGAACTTCATGTTC ATAATGCTACTGTCAAGTCTGACC ATGCTCATATGTACCTATATGTATT GAAGGAGCAACAAATTGGTGATCT TGTTCCATACACAACGAGAGTGGA TGTAGATTCTGGGACAGAAGATTG CGTGGTTGAGACACTTTTGGTAAG GCTGGCTCGTGAAATCCATTCAAT GGTTGGTGTAAAGATGCACCGGT TGGGAGTTTTTGAGTGGGAGGTG AAGCTTTGCATGGCATCATCGGGT CAAGCCAACGGTGCGTGGAGGGT TGTGGTCACAAATGTGACTGGTCA TACCTGCGTTGTGCATGTATATCG TGAACTGGAAGATACTGGTTTGCA CAAGGTGTATCATGCTACCTCTAC ATTGGGTCCTTTGCATGGCGTACC TGTGAATACACCCTTTCAGCCTTT AGGATTACTTGATCAGAAGCGTCT TTTGGCAAGGAAAAGCAATACTAC GTACTGCTACGACTTTGCACTGGC ATTTGAAGCAGCTCTTGAGAATAT CTGGGCGTCGAAAGTCGTAAGTG ATAGCAGGCCTAAGGGTAAACTT GTGAATGTGACGGAGCTCATGTTT GCTGAGCCAAGTGGCTCATGGGGÇ AACTCCCCTTGTTGCAGTAAATCG TGAGCCAGGGCAAAACAAGGTGG GCATGGTGGCGTGGACTATGGAC CTCTGCACTCCTGAGTTTCCTGAT GGAAGAACGATTTTGGTAGTAGCA AACGATGTTACGTTCAAAAATGGA TCTTTTGGTCCTCTTGAGGATGCC TTTTTTGAGGCAGTTACTGATCTC GCTTGTGCCAAGAAACTGCCACTA ATATACTTGGCAGCAAACTCGGG GGCCCGTATCEGGAGCGGCTGAG GAAGTCAGATCTTGCTTTAGAATT GGGTGGTCTGATGAGTCGACTCC TGAATCGGGATTCCAGTATTTGTA TCTTACTCCTGAAGATTATACCCA CATCAAATCATCTGTAATAGCTCA TGAGGTTCATCTATCAAATGGCGA AACAAGATATGTCATCGATACTAT TGTGGGAAAAGAAGACGGACTCG GGGTTGAAAATTTGAGTGGTAGC GGGGCAATTGCTGGTGCCTATTC GAAAGCATATAAGGAAACGTTTAC ATTAACATATGTTACTGGAAGAAC AGTTGGGATAGGCGCATATCTGG CACGTCTTGGGATGCGGTGCATA CAGCGGCTTGATCAACCGATTATA TTAACGGGTTTTTCTGCACTGAAC AAGCTTTTGGGCCGAGAGGTTTAT AGCTCACAGATGCAACTAGGTGG GCCTAAAATTATGGCTACGAATGG TGTTGTCCATTTAACGGTGTCCGA TGATCTCGAAGGTGTCTCAGCTAT CTTGAATTGGTTGAGCTTTGTTCC ACCTTATGTCGGTGGCCCACTTCC TGTTTTAGCACCTGTGGATCCACC AGAAAGGCCCGTTGAGTACCTCC CTGAAAACTCATGTGATCCTCGGG CAGCTATTTGTGGGGTCGTGGAT AGCAACGGTGAATGGGCTGGTGEG GATTTTCGATAGAGACAGTTTTGT GGAGACATTGGAAGGTTGGGCGA GGACAGTCGTAACGGGTCGTGCC AAACTTGGCGGGATCCCAGTCGG GATCGTTGCTGTTGAGACACAAAC AGTGATGCAAGAAATACCTGCAGA TCCCGGGCAGCTTGATTCACACG AACGTGTTGTTCCTCAAGCAGGTC AGGTCTGGTTCCCGGATTCCGCC AGCAAAACAGCTCAGGCATTGAT GGATTTCAACCGAGAAGAGCTCC CACTTTTCATCATGGCTAACTGGC GAGGCTTTTCTGCAGGTCAGCGG GATCTTTTTGAAGGGATTTTACAA GCAGGGTCAACAATTGTTGAGAAT CTCAGAACATATAACCAGCCTGTT TTTGTATACATCCCGAAAACTGGA GAACTTCGTGGTGGTGCATGGGT GGTTGTCGACAGTCGAATCAATTC AGATCATATAGAAATGTATGCAGA AACCACAGCAAAAGGAAATGTCCT TGAACCTGAAGGTATGATTGAGAT TAAGTTCCGAAACAAAGAATTGAT AGACTGTATGGGTCGTCTAGATCC ACAGATTCGAAGCCTTAAAGAAAG ACTTCGAGAAACAAAGTACGATCA AACGATCGTCCAACAGATAAAATC TCGTGAAAAACAGCTTTTACCGAT TTACACTCAAATTGCTACCAAATT CGCTGAACTTCATGACACATCATT GCGAATGGCTGAAAAAGGTGTGG TCAAACAAGTTGTTGACTGGAAAG TATCTCGGTTTTTCTTTTACAAAAG GCTTCGTCGTAGGCTCGCAGAGG CTTCCTTGATCAGTAGTGCTCGTG AAGCTGCTGGTGATACTCTTTCCT ACAAGTCTGCTCATGAGTTGATTA AGAAATGGTTTTTGGAATCGAAAA CTGAAGATTTATGGCTTAGTGATG ATGCTTTTTTCACTTGGAAAGACA ATCTGATGAACTATAATGACAAGT TAGCCAAGCTACGTACTCAGAAG CTCTTGGATCAGTTATTAAAGATT GGTAATTCACCATTGGATCTACAA GCTTTACCACAAGGCCTCGCCGC ACTTTTGCAAGAGGTGAACAA-
ACTCTCTTTTATTTTCCCTTAG 46 Conyza |cD- |6654 ATGCCAGAAGCTCAAAGAATGCCT canaden- | NA- CTAAATGGAAGCCTTAATCTTGGT sis Con- AATGGTTATGTAAATGGGGCCATT tig TCATTGAGGTCTTCTGCTAGCAGA
TCTGCCATTGATGAATTTTGTAAT GCACTTGGGGGGAATAGGCCAAT CCATAGTATTTTAATTGCAAACAAT GGAATGGCTGCTGTAAAGTTTATA AGAAGTGTGAGGACATGGAGTTA TGAAACGTTTGGTTCAGAAAAAGC AATTTTGTTGGTAGCCATGGCTAC ACCTGAGGATATGAGGATTAATGC CGAGCATATTAGAATTGCTGATCA GTTTGTTGAAGTCCCAGGTGGTAC AAATAATAATAATTATGCTAATGTG CAGCTCATCGTGGAGACTGCTGA GATAACACATGTTGATGCTGTTTG GCCTGGTTGGGGTCATGCCTCTG AAATTCCTGAATTACCTGATGCAT TGGACGCAAAGGGAATTGTATTTC TTGGGCCGCCGGCTTCATCCATG GCGGCTTTAGGAGACAAAATCGG CTCTTCTTTAATTGCACAAGCTGC TGACGTGCCAACACTTCCTTGGA GTGGTTCTCATGTGAAAATTTCTG CAGAGAGCTGCTTAGACACAATTC CAGATGACGTATATAGAAAAGCTT GTGTCCATACAACCGAGGAAGCA GTTGCTTCTTGTCAAGTTATTGGT TATCCTGCTATGATCAAGGCATCA TGGGGCGESTESGTEGCAAAGGCAT AAGAAAGGTGCATAGTGATGAAG AAGTCAAGACACTTTTTAAGCAAG TTCAGGGTGAAGTCCCTGGTTCC CCCATATTTATTATGAAAGTTGCTT CCCAGAGCCGACATCTAGAAGTA CAACTCCTCTGTGATCAGCATGGC AATGTAGCGGCTTTACATAGTCGG GATTGCAGTGTTCAAAGGCGGCA TCAAAAGATTATCGAGGAGGGGC CAATAACCATAGCCCCCCCTGACA CAATAAAAAAATTGGAGCAAGCGG CAAGAAGATTAGCCAAATCGGTCA ATTATGTTGGAGCTGCAACTGTAG AGTATTTGTACAGTATGGAAACCG GAGATTATTACTTTTTGGAGCTCA ATCCCCGTTTACAGGTTGAGCATC CTGTCACTGAGTGGATAGCGGAA GTTAATCTACCTGCAGCACAAGTT GCGGTTGGAATGGGCATTCCACT TTGGCAAATTCCCGAAATAAGACG GTTTTATGGAAAGGAAAACGGTG GAGGGTATGATGCTTGGAGGAGA ACATCGGTTCTTGCAACCCCATTT GATTTTGATCGCGCCGAGTCAGTT AGGCCGAAGGGTCATTGTGTTGC TGTACGTGTAACAAGTGAAGATCC GGATGATGGTTTTAAGCCCACCA GTGGAAAAGTTCAGGAGCTAAGTT TTAAAAGCAAGCCAAACGTATGGG CATACTTTTCTGTCAAGTCTGGAG GAGGCATTCATGAATTCTCAGATT CTCAATTCGGTCATGTTTTTGCAT TTGGAGAGTCAAGAACATTGGCTA TTGCAAATATGGTTCTTGGGCTAA AGGAAATTCAAATTCGTGGCGAAA TGCGCACTAATGTTGATTATACAA TTGATTTATTACATGCTCCAGATTA TAGAGAAAACAAAATACACACGGG TTGGTTAGATAGCCGAATTGCGAT GCGGGTTAGAGCAGAAAGGCCTC CTTGGTATCTTTCGGTAGTGGEG GGAGCTCTTTACAAAGCCGCTGC TAGAAGTGCAGCCATGGCCTCTG ACTATGTTGGTTATCTTGAAAAGG GGCAAATCCCTCCAAAGCATTTAT CACTAGTCAACTCTCAAGTTACTT TGAATATTGAGGGGAGCAGATAC ACAATTGATATGGTAAAAAGAGGA CCTGGAGGTTATAGATTGAAAATG AACCAATCTGAGATTGAAGCAGAA ATACATACTCTACGTGACGGGGGÇ TTTATTGATGCAGTTGGATGGGAA TAGTCATATTATATATGCTGAAGA AGAAGCCGCTGGTACTCGTCTCC TCATTGATGGACGGACATGTTTGC TTCAGAATGATCATGATCCTTCCA AGCTGGTGGCCGAAACACCATGC AAACTTCTAAGATACTTAGTCTCA GATAGTAGCCATGTCGATGCTGA CACACCTTATGCTGAGGTGGAGG TAATGAAGATGTGTATGCCGCTAC TTTCGCCGGCTTCTGGAGTTATAC AGTTTAAGATGTCTGAAGGTCAAG CAATGCATGCTGGTGAGCTAATAG CAAGGCTTGATCTTGATGACCCAT CAGCAGTAAGAAAAGCAGAGCCT TTCCATGGAACTTTTCCTCTTCOTT GGGTCTTCAACTGCCATGTCAGAT AAAGTTCATCAAAAGTGTGCTACA ACTCTAAGTGCCGCTCGAATGATT CTTGCAGGCTATGATCACGATATT GATGAATTGGAAACAAAATTTAAG GAGTACGAAGGAATTTCCACCCAA CAAGCTATTGATTTCCCCGCCAAA TTATTATGGGGAATTCTTGAAACA CATCTTGAATTGTGCTCGGAAAAG GAAAGGGGAGCCCAAGAAAGGCT TGCTGAGCCATTAATGAGTCTTGT CAAGTCCTATGAAGGTGGCAGAG AGAGTCATGCACGTGGGATCGTT CATGCTCTTTTTGAAGCATATTTAT CTGTTGAAGAGCTATTTAGCGACA ACATTCAGGCTGATGTAATTGAAC GTCTTAGACAACAATACAAGAAGG ATCTGTCGAGGGTTGTTGACATCG TGATTTCACATCAGGGTGTTAAGA CTAAAAACAAACTGATACTACGAC TGATGGAGCATTTGGTTTACCCTA ATCCAGCCGCCTATAGGGAAAAT CTGATACGGTTTTCTCAATTGAAC CACACTAGTTATTCTGAGTTAGCA TTGAAGGCAAGTCAGCTGCTAGA ACAGACTAAACTGAGTGAACTTCG TTCAAGCATAGCTAGAAGTCTTTC TGAGTTAGAGATGTTTACCGAAGA AGGTGAGAATATAGATACCCCTAA GAGGAAGAGTGCCATTGATGAAA GAATGGAGGATATTGTGAGTGCT CCTTTGGCGGTCGAAGATGCCCT TGTTGGTCTTTTTGATCACAGTGA TCACACCCTTCAAAGGCGTGTTGT TGAGACCTATGTTCGAAGGCTATA TCAGCCATATCTCGTGAAGAGGA GTGTTAAGATGCAGTGGCACAGA TCCGGACTTATTGCTTCATGGCAA TTCATGGAAGGACACGCTGAAGC TGTTAATGTGTCTGATTATGAAAC TATTGATACACAATTGGTAGATAA GAAATGGGGAGCTATGGTTATTAT TAGATCTCTTCAATTTTTACCTGAT GTCATAAGTGCAGCTCTTAAAGAA ACTACTTATAAACATCATGGCACA AGTCAAAATGGGGATGCCAATCC AAGTTATCAAGGTTATATGATGCA TATTGCATTGGTAGGCATCAACAA CCAAATGAGTTTGCTTCAAGACAG TGGTGATGAGGATCAGGCTCAAG AGAGAGTCAACAAGTTAGCAAAAA TACTCAAAGATAAAGAAATAAGTG TGAAACTAAAAAATGCAGGATATG AAGTTGTAAGTTGCATAATACAAA GAGACGAAGGTAGAGGCCCGGTG AGACACTCATTTCACTGGTCAGAA AAGAATCGTTATTATATCGAAGAG CCATCATTGCGTCATTTGGAGCCT CCATTATCGATTTATCTTGAACTG GACAAGCTTAAGGGCTATGAGAAT GTAAAGTACACTCCATCACGTGAC CGTCAATGGCACATGTATACTGTT GATGCTAAACCACTTCCGGTTCAA AGAATGTTTCTTAGAACGCTTGTA AGGCACCCGACAAAAGAATGGTT CTTGCCCTCAGGATACCAAGATTC GGAAGTTGTGGACCCACGGTCTC AGTTAACTTTACCTTTTACATCAAG GAGCATCTTGAGATCTTTAGTGAC CGCCATGGAGGAGTTGGAACTTC ATGTTCATAATGCTATAGTCAAGT CGGACCATGCTCATATGTACCTCT ATATATTGAAAGAACAACAAATAA ATGATCTTGTTCCATATACTAAGA GAGTGGATGTAGATTCTGGTAAAG AAGAAGGTGTGGTTGAGACGCTT TTGGTGAAGTTGGTCCGTGAACTT CATTCGATGGTTGGGGTAAAGAT GCACCGGTTAGGTGTTTTTGAGTG GGAGGTGAAGCTTTGTATGGTATC ATCTGGTGAAGCCAACGGTGTTT GGAGGGTGGTGGTCACAAATGTG ACTGGGCATACCTGCAATGTACAT GTGTATCGGGAAGTAGAAGATACT GTTAAACACAAGGCAGTGTATCAT GCTCCCTCTACATTGGGACCTTTA CATGGTGTGCTGGTGAACACACC CTTTCAGCCTCTGGGATTACTCGA TCAGAAGCGTCTTGTCGCCAGGA AAAGCAATACTACTTACTGCTACG ACTTTGCACTGGCATTTGAAGCAG CCCTTGAGAATATCTGGTCATCAA AACTGCCTGGTGTAAGCAGGCCC AAGGGCAAACTTGTAAATGCGATG GAGCTTGTGTTTGCTGACCGAAG AGGTTTATGGGGCACTCCACTTGT GCCAGTAACGCGCGAGCCTGGAC AAAATAATGTGGGAATGGTAGCGT GGACTATGGACCTCTGCACACCA GAATTTCCTGATGGTAGGACGATT TTAGTTGTTTCAAATGACGTCACA TTTAAAAACGGATCTTTTGGTCCT ATCGAGGATGCGTTTTTTGAGGCA GTCACTGAGCTTGCTTGTGCCAAA AAACTGCCGCTCATTTACCTGGCG GCAAACTCAGGGGCCCGTATCGG GGTGGCCGAAGAGGTCAGATCCA GCTTTAGAATTGGGTGGTCTGATG AGTCAACTCCCGACTCCGGCTTTC AGTATTTGTATCTAACTCCCGAAG ATTACTCTCGTTTGGAATCATCAG TAATAGCACATGAAATTCGTCTAT CCAGTGGTGAAACAAGATGGGTC ATTGATACTATTGTCGGGAAAGAG GATGGATTAGGGGTTGAGAATTTG AGTGGTAGTGGGGCGATTGCTGEG GGCTTTTTCGAAGGCATATAAAGA AACTTTTACTTTAACCTACGTGACT GGAAGAACTGTTGGGATAGGTGC ATATCTGGCCCGTCTTGGGATGC GATGCATACAAAGGCTTGATCAAC CGATTATTTTAACTGGGTTTTCTG CACTAAACAAGCTTTTGGGCCGA GAGGTTTATAGTTCGCAGATGCAA CTTGGTGGACCTAAAATTATGGCC ACGAATGGCGTTGTTCATCAAACT GTATCTGATGATTTGGAAGGTGTC TCGGCTATCTTGAACTGGTTGAGC TATGTTCCGCCTTACGTTGGCGGT CCACTTCCTGTTTTGCCACCCATG GATCCACCAGACAGGCCCGTCGA GTACCTGCCTGAAAACTCATGTGA TCCTAGGGCAGCCATTTGTGGGA CCGTGGATGGTAACGGGAAATGG GTTGGTGGGATTTTCGACAGAAAC AGTTTTGTGGAGACGTTGGAAGG TTGGGCAAGGACAGTTGTAACAG GTCGGGCGAAACTCGGTGGAATC CCTGTGGGGETTETTGCTETCGA GACACAAACGATGATGCAAGTTAT ACCTGCGGATCCTGGGCAGCTCG ATTCACATGAACGTGTAGTTCCTC AAGCTGGGCAGGTCTGGTTCCCG GATTCTGCTAGTAAGACAGCTCAA GCGCTGATGGATTTTAATCGAGAA GAGCTCCCCCTTTTCATTATGGCA AACTGGCGAGGGTTTTCAGCCGG TCAACGTGACCTTTTTGAAGGGAT TCTACAAGCGGGATCGACAATTGT AGAGAATCTTAGAACCTATAAACA GCCAGTTTTTGTCTACATTCCAAA AACAGGTGAGCTTCGAGGTGGTG CATGGGTGGTCGTTGACAGTCGA ATCAATTCAGACCATATAGAAATG TATGCAGAAACAACTGCGAAAGG AAATGTTCTTGAACCCGAAGGTAT GATTGAAATAAAGTTCCGAAATAA AGAGCTGGTAGACTGCATGGGTC GATTGGACCCACTAATTTGCAATC TAAAAGAAAAACTTAAAGAAACGA AGCTCGATCAAGCAATCACCCAG CAGATAAAAGCCCGTGAGAAACA GCTTTTACCAATTTACACTCAAATC GCTACAAAGTTTGCTGAACTTCAT GACACATCATTCCGAATGGCTGAA AAAGGTGTTGTCAAAAAGGTTGTT GACTGGGCAATTTCCCGGTTTITC TTCTACAAAAGACTCCAGCGTAGG CTGGCCGAGGCTTCTCTAATCAA GAGTGCTCGTGATGCTGCTGGTG ACACGCTTTCACACAAATCTGCTC ATGAAATGATCAAAAAATGGTTTTT GGACACAAAAAGTGAAGATATGTG GGTGAATGACGACGCCTTTTTCAC ATGGAAAGATGATCCATTGAACTA TACTAGCAAATTAGCCGATCTACG TACACAGAAGATATCAAATCAGTT ATTAAAGATTGGCAGTTCACCTTC CGATCTGCAAGCTTTACCACAGG GACTCGCTGCACTTTTGCAAGAG GTGAATCCTGCAGCCAAAAATAAA TTGATTGAAGAACTCAGGCGGA-
TAATTGAGTAG 47 Conyza |cD- 4804 CTACTTTCGCCGGCTTCTGGAGTT canaden- | NA- ATACAGTTTAAGATGTCTGAAGGT sis Con- CAAGCAATGCATGCTGGTGAGCT tig AATAGCAAGGCTTGATCTTGATGA
CCCATCAGCAGTAAGAAAAGCAG AGCCTTTCCATGGAACTTTTCCTC TTCTTGGGTCTTCAACTGCCATGT CAGATAAAGTTCATCAAAAGTGTG CTACAACTCTAAGTGCCGCTCGAA TGATTCTTGCAGGCTATGATCACG ATATTGATGAAGTTGTCAAAAACC TTCTTCGTTGTCTAGATAATCCCA AGCTACCTTTCCTCCAGTGGCAAG AATGCTTTGCAGTTCTAGCCAATC GTCTCCCTAAAGATCTAAGAAACA AGTTGGAATCCAAGTTTAAGGAGT ACGAAGGAATTTCCACACAACAAA CTATTGACTTTCCTGCTAGAGTTC TACGGGTCATTCTTGAAACCCATC TTGGATCTTGCTCAGAAAAAGAAA AGGGAGCCCAAGAAAGGCTCGTT GAGCCATTAATGGGTCTTGTAAAG TCATATGAAGGGGGAAGAGAAAG TCATGCACGTGGGATCGTTCATG CTCTATTTGATGAATATTTATCTGT TGAAGAGTTGTTCAGCGACAACAT TCAGGCTGATGTAATCGAACGTCT TCGACAACTATACAAGAAAGATCT CTTGAGGATTGTCGACATTGTCCT TTCCCATCAGGGTGTTAGGAGTAA AAACAAATTGATACTACGGCTGAT GGAGCATTTGGTTTACCCCAATCC GGCTGCGTATAGGGAGAAACTGA TACGATTTTCTCAACTTAACCACA CAAGTTATTCTGAGTTAGCACTGA AGGCAAGTCAACTTTTAGAACAAA CTAAACTAAGTGAACTTCGTTCAA GCATTGCGCGAAGTCTTTCTGAAT TAGAGATGTTTACTGAAGAAGGTG AAAATATGGATACCCCTAAGAGGA AGAGTGCCATTAATGAAAGAATGG AGGATATTGTGAGTGCTCCATTGG CAGTTGAAGATGCCCTTGTTGGTC TTTTTGACCATAGCGATCACACCC TTCAAAGGCGTGTTGTTGAGACCT ATGTTCGAAGATTATATCAGCCAT ATCTCGTGAAGGGGAGTGTTAGA ATGCAGTGGCACAGATCCGGACT CATCGCTACATGGCAATTTATAGA AGGACTCATTGGAGAAGTTAATGT GCCTGACTATGAACAGAATGAAG CTCCCTTGGAAGACAAGAAATGG GGAGCTATGGTTATTATTAAATCT CTTCAATTTTTGCCTGATGTCATAA GTGCATCTCTTAAAGAAACGAGTC ATAACCTTCCCAGAACAAGTCAGA ATGGGTTTGCTGGTCATAGTAACC ATGGTAATATGATGCACATTGCTT TGGCCGGCATAAATAACCAGATG AGTTTGCTTCAAGACAGTGGTGAT GAGGATCAGGCTCAAGAGAGAGT CAACAGGTTAGCAAAAATACTCAA AGATAAAGAAGTAAGCTCGAGTCT TAAAAACGCAGGGTATGGAGTGA TCAGTTGTATAATACAAAGAGATG AAGGGAGAGGCCCCATGAGACAC TCATTTCACTGGTCAGAAGAGAAT CATTATTATATTGAAGAGCCATTAT TGCGTCACTTGGAGCCTCCATTAT CGACATATCTTGAACTGGACAAAC TTAAGGGCTATGATAATATAAAGT ACACTCCGTCGCGTGACCGTCAA TGGCACATGTATACTGTTGATGCT AAACCACTTCCGGTACAAAGAATG TTTCTTAGAACTCTTATAAGGCAT CCAACAAAGGAATGGTTCTCGCC CTCAGGTTACCAAGGTTCAGAAGA TGAGGGCCCACGGTCTCAGTTAA ATCTCCCTTTTACATCAAGGAGCA TCTTGAGATCATTAGTGACGGCTA TGGAGGAGTTGGAACTTCATGTTC ATAATGCTACTGTCAAGTCTGACC ATGCTCATATGTACCTATATGTATT GAAGGAGCAACAAATTGGTGATCT TGTTCCATACACAACGAGAGTGGA TGTAGATTCTGGGACAGAAGATTG CGTGGTTGAGACACTTTTGGTAAG GCTGGCTCGTGAAATCCATTCAAT GGTTGGTGTAAAGATGCACCGGT TGGGAGTTTTTGAGTGGGAGGTG AAGCTTTGCATGGCATCATCGGGT CAAGCCAACGGTGCGTGGAGGGT TGTGGTCACAAATGTGACTGGTCA TACCTGCGTTGTGCATGTATATCG TGAACTGGAAGATACTGGTTTGCA CAAGGTGTATCATGCTACCTCTAC ATTGGGTCCTTTGCATGGCGTACC TGTGAATACACCCTTTCAGCCTTT AGGATTACTTGATCAGAAGCGTCT TTTGGCAAGGAAAAGCAATACTAC GTACTGCTACGACTTTGCACTGGC ATTTGAAGCAGCTCTTGAGAATAT CTGGGCGTCGAAAGTCGTAAGTG ATAGCAGGCCTAAGGGTAAACTT GTGAATGTGACGGAGCTCATGTTT GCTGAGCCAAGTGGCTCATGGGG AACTCCCCTTGTTGCAGTAAATCG TGAGCCAGGGCAAAACAAGGTGG GCATGGTGGCGTGGACTATGGAC CTCTGCACTCCTGAGTTTCCTGAT GGAAGAACGATTTTGGTAGTAGCA AACGATGTTACGTTCAAAAATGGA TCTTTTGGTCCTCTTGAGGATGCC TTTTTTGAGGCAGTTACTGATCTC GCTTGTGCCAAGAAACTGCCACTA ATATACTTGGCAGCAAACTCGGG GGCCCGTATCEGGAGCGGCTGAG GAAGTCAGATCTTGCTTTAGAATT GGGTGGTCTGATGAGTCGACTCC TGAATCGGGATTCCAGTATTTGTA TCTTACTCCTGAAGATTATACCCA CATCAAATCATCTGTAATAGCTCA TGAGGTTCATCTATCAAATGGCGA AACAAGATATGTCATCGATACTAT TGTGGGAAAAGAAGACGGACTCG GGGTTGAAAATTTGAGTGGTAGC GGGGCAATTGCTGGTGCCTATTC GAAAGCATATAAGGAAACGTTTAC ATTAACATATGTTACTGGAAGAAC AGTTGGGATAGGCGCATATCTGG CACGTCTTGGGATGCGGTGCATA CAGCGGCTTGATCAACCGATTATA TTAACGGGTTTTTCTGCACTGAAC AAGCTTTTGGGCCGAGAGGTTTAT AGCTCACAGATGCAACTAGGTGG GCCTAAAATTATGGCTACGAATGG TGTTGTCCATTTAACGGTGTCCGA TGATCTCGAAGGTGTCTCAGCTAT CTTGAATTGGTTGAGCTTTGTTCC ACCTTATGTCGGTGGCCCACTTCC TGTTTTAGCACCTGTGGATCCACC AGAAAGGCCCGTTGAGTACCTCC CTGAAAACTCATGTGATCCTCGGG CAGCTATTTGTGGGGTCGTGGAT AGCAACGGTGAATGGGCTGGTGG GATTTTCGATAGAGACAGTTTTGT GGAGACATTGGAAGGTTGGGCGA GGACAGTCGTAACGGGTCGTGCC AAACTTGGCGGGATCCCAGTCGG GATCGTTGCTGTTGAGACACAAAC AGTGATGCAAGAAATACCTGCAGA TCCCGGGCAGCTTGATTCACACG AACGTGTTGTTCCTCAAGCAGGTC AGGTCTGGTTCCCGGATTCCEGCC AGCAAAACAGCTCAGGCATTGAT GGATTTCAACCGAGAAGAGCTCC CACTTTTCATCATGGCTAACTGGC GAGGCTTTTCTGCAGGTCAGCGG GATCTTTTTGAAGGGATTTTACAA GCAGGGTCAACAATTGTTGAGAAT CTCAGAACATATAACCAGCCTGTT TTTGTATACATCCCGAAAACTGGA GAACTTCGTGGCGGTGCATGGGT GGTTGTCGACAGTCGAATCAATTC AGATCATATAGAAATGTATGCAGA AACCACAGCAAAAGGAAATGTCCT TGAACCTGAAGGTATGATTGAGAT TAAGTTCCGAAACAAAGAATTGAT AGACTGTATGGGTCGTCTAGATCC ACAGATTCGAAGCCTTAAAGAAAG ACTTCGAGAAACAAAGTACGATCA AACGATCGTCCAACAGATAAAATC TCGTGAAAAACAGCTTTTACCGAT TTACACTCAAATTGCTACCAAATT CGCTGAACTTCATGACACATCATT GCGAATGGCTGAAAAAGGTGTGG TCAAACAAGTTGTTGACTGGAAAG TATCTCGGTTTTTCTTTTACAAAAG GCTTCGTCGTAGGCTCGCAGAGG CTTCCTTGATCAGTAGTGCTCGTG AAGCTGCTGGTGATACTCTTTCCT ACAAGTCTGCTCATGAGTTGATTA AGAAATGGTTTTTGGAATCGAAAA CTGAAGATTTATGGCTTAGTGATG ATGCTTTTTTCACTTGGAAAGACA ATCTGATGAACTATAATGACAAGT TAGCCAAGCTACGTACTCAGAAG CTCTTGGATCAGTTATTAAAGATT GGTAATTCACCATTGGATCTACAA GCTTTACCACAAGGCCTCGCCGC ACTTTTGCAAGAGGTGGATCCAGT GACCAAAAATAAACTAGTCGAAGA ACTCTTGCGCGTAATTAAGTAGGT AATTATACACAAAGCTCATCAGAT TCTTTCTITGTTTGTCAAAGTGAG AAGCCTTTTGAGCAGTGTACATTA TAAGTAGGTGTCATAAGAAAACAG GCTCAAAATAGTTTAAAGTATATG AGGTTTACCATGTTCAGATTGTTT TATTTTTCTTCATAAATTGTATAAT ACCATCACATTTCTATCGCATTTTT
TATATATCTATATATAAATGGTCA 48 Conyza |jcD- |454 GGTCATTGTGTTGCTGTACGTGTA canaden- | NA- ACAAGTGAAGATCCGGATGATGG sis Con- TTTTAAGCCCACCAGTGGAAAAGT tig TCAGGAGCTAAGTTTTAAAAGCAA
GCCAAACGTATGGGCATACTTTITTC TGTCAAGTCTGGAGGAGGCATTC ATGAATTCTCAGATTCTCAATTCG GTCATGTTTTTGCATTTGGAGAGT CAAGAACATTGGCTATTGCAAATA TGGTTCTTGGGCTAAAGGAAATTC AAATTCGTGGCGAGATGCGCACT AATGTTGATTATACAATTGATTTAT TACATGCTCCAGATTATAGAGAAA ACAAAATACACATACCGGTTGGTT AGATAGCCGAATTGCTATGAGGG TTAGAGCAGAAAGGCCCCCTTGG TATCTTTCAGTAGTTGGGGGAGCA CTTTATAAAGCTGCTGCTAGAAGT GCAGCCATGGTCTCGGAC-
TATGTTGG 49 Conyza |jgD- 19367 | TTITGGTGGTGGTTTCGTGGTCTAA canaden- | NA- TTCGAAGAAACGAGTGAGATATCG sis Con- GTATTTTAAGTTTTCCGGCGAACT tig TTCCGATGAAAGTTAGCCGGAGA
AGATGAAGATGATGACAACAGAAA ATTAAATTTCATTTTTTGTCCCTGA ACTTGTCACTTTTCGCACTTTAAG TCCCTCACGTGTTTTGCACGTGTG GGACTTAACGGCTGAAACTTAACA CCGTTTGGCGAGGGACGTCGATT GCAAAAATCTGTCAAGTTTAGGGT CAAAATTGTAATTTTITTCATITTTAG GGATGAAAAGTGAAAAACGCGCC AAGTTTAGGGACGAAAAATGTAAT TTACTCTAAGTATTATGTAATTTGT TTTGTTATTAATAAAACATATAAAT TAAAAAAAGGTTAGTTATTTAAAGT TTATAAATGTTAAGGATAAATTATT AAAANNTGAAGAAAAGGTTGGGA GTTTTGGTTGCCACTAGAAAAAGG TTGAAAAAAAGGTTGGAGGGTTGA AATGAGGTGGAGTAATTTGATTGG GTATTTAMAGGGAGATGAGAGGG TTGAACCCTCGGCTCCGTCCCCC CTTATAGGACACCTTGTTCATGAG GATACTTTGATATTTTAATGGGGA AATGATAAATTCTTTTAAATTAACC TAAAAATCATTCTAAAACTATAAGA AGATGATATGTGATATCTACTAATT CTCTTCTCTACTETOGCCCTTTITTT CACATATAATCATCTCATTATTAAG AACATTTTTAGGTTATTTAGTTAAA AGAATGAATCATTTCTCATTTTAAT ATAAATGGTTAATTTGAATTGACAT CAATCACTGGCGAGAAACACAAA GGTAAAAGAGTAGTGAACACGAA GGTAAAAGAGTAGTAAATTACCAA TCATATCCTTCCTCCTTTATATTTT GATGGAACAAACACAAATTTATTT TAGAATTTTTTAAAAAAATATATTA AACCGGGTAGAACATAATCATTAT TATTGTTACACGAAATTTATTGTAC ACCGTGTTAGCTGGTTACAGTAGT ATTAATTAATTGGTCAAATATATGT GCATTAAAATCAGGAACACATTTA TAACAAACATAGCGAGATTTTAGG AGAACTTTAATTGAAAATTTTACCA TTACAGTAATTAATTAACTTAAACA CATACAAAACCCTATACATTATTTA CATTGTCTACATTTCATTACTGTTG TTGGTTTCTGATCGAATGCCATGA ATTTTCGGGCATTTGATCTGAAGC TCAACATTTTTCTGGGCGATTCAA ATAAGCGTTTTACTGTTACAAAAA GTTTCGTCTCAACGGGTGACCACT ACACGACTTCTGATAACACCAATC CGACCAGTCTTACAAAGGTGAAG GTGAGCGTCAATATTTAGTTTAAT CTCATCGTCTGTGTTTTAAGCTTITT TTGAGGTCTAAACCTTTTTGGTCA GCAAAATTTGAAAATTCTTTTAATA TGTTAACTTCTTTTGGAAGCTTTA GAGATTTATATATTCTTAATCCATA ATAATCTATAATTCTATATTTCOTIT ACTCCTCTATAAAGCATATTGCTTT TTTTATTTTTGGAAATTAAGCATTT TTTAAAATATTTTCATAATACCCTT ACACCCCTACCTTCTTTCTAATCA
TTACACGCTCTCCTCGACCTTCTA TCACCCTCCGCCGCCGcceteoT
TCTCCACCACCGCCCTCGATCTC CACCACCGCCTCCCTTITTATATTG TCATCGCCTTTTAGCCGTTGCAAC GCGCGGACACTATGCTCGTATTAA AAGTAGTAACGTAATAAACATAAA GTTTACGTAAAGTTTATATATTTCA TTATTTTGTTATGATTTTGTACTGA TGAATATATATTTAAGCTAAAATCA TTCACTCTAGAGTGTAAGTCGAAC GGGTCCAAACTGAACTAAACTATT TGTCTATGGTAGTCAAATTCTTAAT CTTTTTGGTATCGATCGTTGTGTA GTGTTGCACACCTCACTTGATATT AGTTTTATGTGATTATATATGGTTA ATTTAATTTTTCTITGATTTITGAT CATGGTCTTAAATATTATTAAAGGT GAAGAAACATGTGAAGAGGGATA AATTTGGAGAAAGAATGGCATCAC TAAAACAGATAGTGTCACCCTATG GCAAGGTTAGTCCTTCTTTAAGTT TATTAATTATATGTAATTTGTTTGA TTAGGTATATCATATATGTATACTA GTTGTTTTGATTTCCAATCTATACA AGTAGGATTTTGCTAAACATAGTT GTAAGGGTTATAGTTACAACACAA TAGAATGGTATACATACATTATAC ATATATAAAGATATATAACTGTTTA TTAATAATAATCTTTAACCGTCATG TAAACCAATTTACTTTGCTTITTATCC ATATCCTTAAAGGCTATGAATAGC ATAGTCGATGTAAGTATATGGTTG CTTAGACGGTGTGTTAATGTTGAT CTTACAGGAGTCTAGACTTGGACC ATTGTGTTTTAGAGAAGAAGGGAA TCGAACGCAAAGGTAAAACTTCCT TTATTTTTAAGAGCATAGTTATAAT ATCATTCAAATTTAACCAACAATTT CTGTTACATACATCGAAATAGGCT TGATTACTCATACCTATAGAGATG AGTGACATGTGTGTATGAAGATTT ATATATTGAATTGTAGGATATCATT TTCCCATTTCTAATGTACTAGTTAA TTATGGTTTGCGGTTTITTITCITTG TTGTATGTCCATTACAAAATTACA GTTGGACATCTTCTTGGTGGAATT CAGATGATATAAAATAGTTAATTTT ACCAAACACTACATCATTGGTAGA GAGAAATTAGAACGTAGATAAATG GTTTGTAAGTTTCAAAAGAGATAC TCGTATTACATAAAATGTTGTCTTT TGCAATTCGCAGATTTCCAATTAC AACAGATTTGACACAATGTTCTAT TATTTGTTAATCCAACCATGAACC ACTAATAAAACAGTACAAACATCT TGAATAAAAAAAAGCCACCAATAC ATTATTGATTGTTGTATGCTTTTTG TCTCCATATAATGACCAGTAATAT CAAAAAACATGTATTTTATTCTTAT TCTAGCTTAAAAAGGTTCAAAAAT GCACATCCAACTTTCTCTCOTITCTIT CCAATCATAGCTTTTCAAATTAAAA GCATACACGTAAAAGAAACATATG GATGTAGATTGATATGTGTGTGGG GGGTAGTTGGTTAACCATGTCAC GTGCTCTGCATCACCTCCCATCCOT TGGACCCCAATTTGTTTTTTGTAC CTACTACATATTTAAGTAACTTTAT GGCACCTCACCAAAAACCAACCA AACAAACCAAACTCCCAACTATAC ATCACTTAATTGCACACACACATA TACCTCAACAAGTACTTACATCTC TCCCAGATTTCTGTCATTCCAATTT TCTTGTTTTTAATCACAATTTTGITT GTTGTTGTCAATGTCTGTCTCTTIT CAAACCAGCTAAAAAAAGAAGCAA ATTCTTGATTTGATTCAGCTGTTGT TCCACTTGTTTATGGTTAGTCTTTC TCATTCTTTCACCCCCCAAGTTTA AATCTTTGAGTTAATTTCTTCAAAT TCCTGTGTTTTTTGAACCGGGTTT TTATCAGTTTTGTTGAGTTTAGCAA AAAAGTAGAGTTGGGTATGTAAAG ATTGAATCTTTTTACTGGGTTTATG TAATTTCTTTGAAATTTATAAGTTT CTTGCAATGGGTATATGATTTITTCT ATTAATTGAAGTGGTTAATAACAG GATTTGGTGAGTAAAGTTTGAATC TTTCGAGTTATGGATTTATGTCATA CCTTTTCTTGCCCTTCAAAATAAA GTCAAAGCTTTAGTTTTGTGATTT GACTTTGGTATGCTGTTGCTCCCA TGAATATTTTCATGCTGTTTGTAAA TTGTAATATATATTTTGATAAATTC AATTTTGTTATATTTGTTTCCTGAT AAAGTTTTAATGTGATTAGTGATTA CTTCAATTTGATGAGTTCAATAATA ATAAGAAATTTAGAACTTTGAACC TCGTATTTCTAATTCGAGGTTTCC TAGCTCTATGTAAACCCCACTATA TTCTCCATTATAACATACGTTTATG TGTTACTTTATTTAGACATTTTAAT ATTTGACTCAATTATAACATAGGTT CAGCTGAAAATTTAATTTCITTIGITT AGTGAATTGTTGTGACTTITTITIIT TGGTAGTTTGCGTTGTGATAGTCA GGAGACAGAAAGGGCAATTTGTTT CTGTTCTTTTTAAGTTAGATAGGT GACCATTTCGGTAGATACTAGATA GTGCAAAGATATAGTGTTTITITGT AAGTACCAAGTACTTTATGAACTT ACCCAATGATAACAACTTTTGATG GTTCAGTGGTTCAGCCTTCTCTTT GTCCCTAGACTAATTAGTCCAATC TATCTCTCAGTATATATTTTTTAGG TATTGACATATTTTATGATATTGGC AAGTTGGTAGTTTACTTTCAACTTT TAAGCAATATATGGACATATCCAC ATATATCAGTTCCATATTACTAGCA TGTATCCTATTCTGGGTTAGTATG CTACAAAAAGGGTTTACATGTCAA ATGCAGAATTGTTCAAAGAAAACG AGTTGTTAGACCTAATAAGTCAAA GTAATGCTTACTCTACACTTTGCT TACTGTTTGGCAGTGGCACCATGT CAGAAGCTCAAAGAATGCTTCTAA GTGGAAGTTTCAATTATTATGGTA ATGGCATTGTAAATGGGGCGATTT CACTGAGGTCTTCTGCTAGTAGAT CTGCAATTGATGAATTTTGTAATG CACTTGGAGGCACCAGGCCAATC CAAAGTATTTTAATTGCAAATAATG GAATGGCGGCTGTAAAGTTTATAA GAAGTGTGAGGACATGGAGTTAT GAAACATTTGGCTCAGATAAAGCT ATTTTGCTGGTAGCCATGGCTACA CCGGAAGATATGAGGATAAATGC CGAGCATATTAGAATCGCTGATCA GTTTGTTGAAGTCCCTGGTGGTAC AAATAATAATAATTATGCGAATGT GCAACTCATTGTAGAGGTATGTAG CTTATATACGTGGATCCTACATCA TGATTTATAAGCTTTAAAATGATCT ATTTTATGAAACATTGTGCATTTAA TGATGCCTGAAAAGATTATGTTTC CAAGACTTATTTTGCTTAACTTGTT GGATCAAAATGTTGATCTGCTTCC ATGAATATAGTAATTCGAATATGTT GGTTTAATCTTCACTTTCAAAAAAA AAAAAAAATACTTCTTTITTATGTTA GCATTTGAGTTTGAATCTCAAGAG AACTTATTTCACTTTTGAAATCGAT ATGGATGTGTTGAACATGTAATTG ATAATCAGCAACATTTTAAAATTTA TTAGAAAATGACGAGGGATGCCT CTTCAGGCTACGCGGCGAGCCTT TGGCTCTAATGTAAGCGGCCTAAC CGGTATACCCGGGTCTCTTCTGA GATCTTTGGGTCACCTTACCACTA GACCCCCTTGGAGAAGGTTTTAAA AAGTATTAGAAAGTATATAAATATA AAATAGAAACGATATGTAAAATTTT AAAAATATGTTTCATTGAGTTATCT TACACCTGACTATTTGATATTGAG CATTAATACGAGTTTGATGGAAAA TATAAAATAATTAATATTTAGCTAT CATCATCAATTCCTTTAAAATGGTT CATTTATGATTTATGACTTCAGACT GCTGAGATAACACATGTTGATGCT GTTTGGCCTGGTTGGGGCCATGC ATCCGAAATCCCTGAGCTGCCTG ATGCATTGGAAGCAAAAGGTATTG TATTTCTTGGGCCACCAGCTTCCT CCATGGCAGCTTTAGGTGATAAAA TTGGTTCTTCTTTGATTGCACAAG CTGCTGATGTACCGACACTTCCTT GGAGCGGTTCTCATGTAAGATTTT TTTTACTATTGTAGTCTTTGTCACA TCAACAATGATCCTTATACTTITTAA CTCCATAAAGATTGCATCGTTCTA TCTCATATTCTCTATAATCTAAAAA AATTCTATATTCCTCTTATTTGTGA AAAGTCTGAACTTCATAACAAAAT CACATCTTGTACCTCTTATATATTA AACTGCATCTTTATGCCTCTAATTT ATTGGAAACAAGATCTTTAAATCC TTTAAAGGTTGCATCTTTATACCTC TTATTCTGTAGAAATTACATTTCAT ACCACTTGTTCTTTGCAATTTCGC ATAGATATTAATGCCTACTCTTTAA AAGATACTTTTCTACTTCTTTACCT CTATAATCACATCTTTGTACCTTTC ACCTCTCCAGTCTTCTTACTCOTCOT ACAGTCACATTTTTAGGTAAAAATT CCTGTGGATAGCTGTTTGGACACA CTCCCGGATGATGTATATAGAAAA GCGTGTGTGCATACAACAGAAGA AGCAATTGCTAGTTGTCAAGTTGT TGGTTATCCAGCAATGATTAAGGC ATCATGGGGTGGAGGTGGCAAAG GCATAAGAAAGGTTTGATTCTTTA CAATTGGGAAATTATTTCTTCOTCCOT CAAAGTATACGGCAAACTTTTAAA ACCAATTACCTATTGAAACTTTAG GTGCATAATGACGAAGAAGTCAA GGCACTTTTTAAGCAAGTTCAGGG TGAAGTGCCTGGTTCCCCTATTTT CATTATGAAAGTTGCTTCTCAGGT AGGACAATGTTGTAATTGTTATTAT TTTCCCAATTTCAACTCAAAACCC ATTATCATTATAATAATATGTTGAT TTCTTGTATATACAGAGCCGACAT CTAGAAGTGCAGCTACTATGCGAT CAACATGGGAATGTAGCAGCTTTG CATAGTCGTGATTGCAGTGTTCAA AGGCGACATCAAAAGGTAAGTTCA TGTTTGTCCTTTTTACTTTCOITITTITT ATCCTGTTTTGTAACTCTAATTTTA TTTAATACTTGATATGTCAAGATTA TTGAAGAGGGGCCAATAACCATA GCTCCACATGACACAATAAAGAAG CTTGAGCAAGCGGCGAGAAGATT AGCAAAGTCGGTTAATTATGTTGG AGCAGCCACTGTAGAGTATTTGTA TAGCATGGAAACTGGAGACTATTA CTTTTTGGAGCTCAATCCCCGGTT ACAGGTGCTTGCAATTTCTGTTTT GTGGGTCCTAGTTATGTGTCCTAA GAAGTAAGATGAAATGGTGGGCT CCAAGATGGTTATGATTTGTITTITTC TGAAGCTATGTATGTGGAACCTTT CTTTAGGTTGAGCATCCAGTCACA GAGTGGATAGCGGAAATCAATCTA CCTGCAGCACAAGTTGCGGTTGG AATGGGCATTCCTCTTTGGCAAAT ACCAGGTTAGATATCAAAAGTTCG TTTTTTGTTGACTATCATAGTTGGT CTTTTGCTACAATGCAACCATCAT GTCAACTATTTTCTTAATTGCTCTA CATGTCTTGTTGGCTTAGAAATAA GACGATTTTATGGAATGGACAATA GTGGAGGATACGATGCTTGGAGG AGAACATCTGCTCTTGCAACTCCA TTTGACTTTGACAAGGCAGAGTCT ATCAGCCCAAAAGGTCATTGTATT GCTGTACGTGTAACAAGTGAGGA CCCAGATGATGGATTTAAGCCCAC TAGTGGAAAAGTTCAGGTTTGGAA GCAGACTAACATATACCATATACC CCTACAAATATAATATATATCCTTT TTTITTITITTITTACCATATTGATC GAATTCCACTTTTAGGAGCTAAGT TTTAAAAGCAAGCCAAATGTCTGG GCATACTTTTCTGTCAAGGTACGC TGGGTTCAAACCTTTITITITITITT TTGAACTTCCAATTGACATATTCTA AAATGTTTGAACATTGCAGTCCGG AGGAGGCATTCATGAATTCTCAGA TTCTCAATTTGGTAAAGACGACTG GATCTTGTTTGGTTGAAATATCTT GAATACTCACTTATTGGTGTAGTT CAAGTTTACATTCTTGGTCAAAAC GTTCATGTTCTCATTTTAATTCTGT ATCTATCTTAGGCCACGTTTTTGC ATTTGGCGAGTCAAGACCTTTGGC TATTGCAAATATGGTTCTTGGGCT GAAGGAAATTCAAATTCGTGGCGA GATCCGTACGAATGTTGATTATAC AATTGATCTGTTACATGTGAGCAT TTTGGGGTTTCACAGCTAACAAAT TTCTTATTTTGTTTACCATAATGAG TTACTTCATGGCGATATAAGGGGT GAGCCATGGAGCAAGTGCCATGT ATCTTAACAGATAAATTGTTATGTT CATGTTTGGCGAGTACTTACACAT TTGAGAATGTCGAGAATTTGATTA TATTTCACCAAACGTTCTTATTGCT TCACCTAAAATGTGAACGTTTTCT TACATGCTTAGTTTITTATTCCTITT TCTATACTTGTAGGCTCCTGATTA TAGAGAAAATAAAATACATACCGG TTGGTTAGATAGCCGAATTGCTAT GAGGGTTAGAGCAGAAAGGCCCC CTTGGTATCTTTCAGTAGTTGGGG GAGCACTTTATGTAAGTACAAAAT ACCTCTTTCTTITCTATATTOEGTCAT TTTTAAAGTACTTTTACTTACCATT GATGTTTGTTAACTTCAGAAAGCT GCTGCTAGAAGTGCAGCCATGGT CTCGGACTATGTTGGTTACCTTGA AAAGGGCCAAATCCCTCCTAAGG TTTGTCAGATATTTTAGTATTITTTT TTTAATTTTTAAGAGTTGGTTCTCG TAATGTTTACATTGATGATCAGTAT TTGTCTGTTTTCTTACTTTCAGCAT ATATCATTGGTCAACTCACAAGTT TCTTTGAATATTGAGGGCAGCAAA TACACGGTAAATAACAAGATAACT GCCTATCGTTATTCEGTTCATAAAA ATGGTTGTTCTTGAAGTTTTCTITT GTGTGTTITTITITTCTTCTGATTITTT TTCTTTTTATTTGTTAGATTGATAT GGTAAAAAGAGGGCCAGGAAGTT ACAGATTGAGAATGAATCAATCCG AGATTGAAGCAGAGATACATACAC TACGTGACGGAGGCTTATTGATG CAGGTACTTAATCCATACGCTCTA TTTITTCTTTCTATTTGGTTTATTCOT GTCAAATTTTCTTITTTATTTGGTTT ATTCTGTCAAAATTTCTTTTTATITT GGTTTATTCCGTAGTTAGTTTGTG ATTAACTGATTACTATATTAAGTCA TTGGTTGGTATGTATACATATAAA ACTCGAATATAAGCATTTTAATGAT GCCAAACCTATATGTAGTTTTACT CTTTAGGATTTCATGATATACCTA GGAAATCCCTCGTGTCTTTGTGGC AGCTAGCAAGTTGAAGATTAATAA TATCAATAAAGAAATTCAGAGAAT TTAATGCAGCATGTTCTAAGGGAG TGTTCGGGGATGCATTCTGAAAAT AATTATGTGATATTTAGTAAAATTG CAATTAAACGTGGTGCAAGAAATA GTGTTTGGATATGCTTCTGCTATA AAGTTCTGGCAATCGCTGTATTGA GTGTTTGACGGATTATGTCTATTT AAGAAGGTGGTAGATAAACTAAAA GTATACATGGTTAGTGGTGCTGTA AGCATTTGCCATCAAAAAGTAGGT AGATAAAGGAAGAGTGCTATAAGT AGTTTTATGCTACTTTTTGGTTATC GAGTTCGTTGCAGCTAGTATCAAA CTAATTCTTTAACTATCGTAGCTGT AATAGGTCACCCTGAACATTTCAA TTTATTGCAACCTTAAGTTACATCA TTTGATAATCATGTTCAAGACACA TTCTTATTTTATACTCTGATATCAT ATGATTTGTGGTTGGTTGATTCAA TGATGTAGTTGGATGGGAATAGTC ATATATTATACGCCGAGGAAGAAG CTGCCGGTACTCGCTTGCTTATTG ATGGACGGACTTGCTTGCTTCAG GTGCGAACAACTAGTTCTTITCITT GAACTTTATTTAGAGGTTGCCATT TCAACCATTTATCTATGATGGGAC AATTTAAACAATGTTTTACCCTTAA TGGTGTATTCAAATGGGTCAACAG TGACCCAAAGTACATTCTCACTGG AGCAAACTGCCTGTATCATTTITTTT TTGTGAGGTTCATTGTTTTTGAATA ATATTGTGTTAATTTTCATATTTAG TAGACTAAAGTAATTATGTAAGTT GTTGTGAACCCGTTCGATCTGCTC AGGTTATACTCGACCGGTTGCAAT CCTCCTAATTTGCCACCTTTACTA TTACTTACTATTTGGGTTACCTGTT TATAGAATGATCATGATCCTTCCA AGTTGATGGCTGAAACACCATGCA AACTTCTAAGGTACTTGGTCTCAG ATGATAGCCATGTTAATGCTGACA CACCGTATGCTGAGGTTGAAGTTA TGAAGATGTGTATGCCACTCCTTT CACCGGCTGCTGGAGTTATACAAT TCAAGATGTCAGAAGGTCAAGCC ATGCAGGTTAGCATGTCACTTTITT CCCCATTTTTAAGAAGTATTTACAT TGTTCAGTTTTTCCGAACATCCAA GAATAAAGCTCTTGGTTCTATGTT TTTGCCAACTACTTACAGCTATTTA TATTTACATGTTAATAAAATGTTCT ATCGATTGACTTCTTGAGTCATTG TGCTTATCGCAACTCAATCTTCGT TATTGTACAGTGATTTTTTAAATGT AATACTGCCAACTTTTTGAATAAAT CGTATCAAATGTAATCTTTAAGCT ATATAACAAACATATGAATTTCGAT TTCCAAATAATATCTACAGTTCACA AACAAATGCTTGTTTCCTGTTTGTT AATACCATTTTTGTCTTCTCTAAAT CATACATACCAAAACCAAAATTGT TGATCATTTCTGATGAATATAAATC TTTGTATATGTAGGCTGGTGAGCT TATAGCAAGGCTAGATCTTGACGA TCCGTCAGCTGTAAGAAAAGCAG AGCCTTTCAATGGAAACTTTCCTC TTCTTGGGCCTCCAACGGCCATG TCAGACAAAGTGCATCAGAAGTGT GCTGCAACTTTAAATGCTGCTCGA ATGATTCTCGCAGGCTATGATCAT AACATTGATGAAGTAACTTGTTTG CCATTTACTGATTTCAAATTITCTG AAAGATTATTCTGTTAACAGTTCT GATCTTTGATCGTAGGTTGTGCAA AACTTGCTTCGTTGTCTTGATAGT CCCGAGCTTCCTTTCCTTCAGTGG CAAGAATGCTTTGCAGTTCTAGCA AATCGTCTCCCTAAAGATCTAAGA AACAAGGCAAATTGATATTTTACC CTTITITITITCTTITTCAAGCAGTT AACATTGGGATTATTTTTCTAAATT CAATATGTTTTGTATATTCAGTTGG AATCCAAGTTTAAGGAGTACGAAG GAATTTCCACACAACAAACTATTG ACTTTCCTGCTAGAGTTCTACGGG TCATTCTTGAAGTTAGTTGTGATC AGTAGTTTTCTTTATAAGTCCTTTC TTTGATTTAAAGACATAATTTAGTT ATATGTTACCTTTGTAATGTTTTCG TTCAGACCCATCTTGGATCTTGCT CAGAAAAAGAAAAGGGAGCCCAA GAAAGGCTCGTTGAGCCATTAATG GGTCTTGTAAAGTCATATGAAGGG GGAAGAGAAAGTCATGCACGTGG GATCGTTCATGCTCTATTTGATGA ATATTTATCTGTTGAAGAGTTGTTC AGCGACAACATTCAGGTGCGTTT GTTAGGATCGCCGATCCAGTATTT TGGATTTTCGATAGGGCATGCACT TGCATTACCATAGTCAGTTTATATT TTATTTCATCTTGTTACACGACAAC AAAGTACCTTTTTTCAAAGTATAAA ACTGCACAGGTTATGTGCTCCCAA AGGGTTTTTTAATACTTTGATCTAT GTGGAAATGGTATAAGAGTTTTAA TCATTTTGACATTAATGTCTGGATA AATTTGTTACGGGTTAAACCAATC AATCTAAGCCAAACCAAAAGTTAC CTGCAAAAGCTATTACCTAACCCA CCCATTTTGCCACCTCTGTTGGTT TTCTTTAGGTCTACTAATGGTTATC GAGTAAATTATATTATAACATAAGT AGTAAACCAAAATCCTGTACCTTT TAGGCTGATGTAATCGAACGTCTT CGACAACTATACAAGAAAGATCTC TTGAGGATTGTCGACATTGTCCTT TCCCATCAGGTACACATGTITTITTT GGTTTTTGTTCTCCCCTTTAATGT GTATTTTATACCGATCATTAATATA TGTCCATGCAGGGTGTTAGGAGT AAAAACAAATTGATACTACGGCTG ATGGAGCATTTGGTTTACCCCAAT CCGGCTGCGTATAGGGAGAAACT GATACGATTTTCTCAACTTAACCA CACAAGTTATTCTGAGGTCATCAT CGTCATATATATACACTGTTACAAT TTTGATCATCTCAATCACTTTTCTG TTAGTACTGAGTTTATGTTAATTGA TTATTATTAATAGTTAGCACTGAAG GCAAGTCAACTTTTAGAACAAACT AAACTAAGTGAACTTCGTTCAAGC ATTGCGCGAAGTCTTTCTGAATTA GAGATGTTTACTGAAGAAGGTGAA AATATGGATACCCCTAAGAGGAAG AGTGCCATTAATGAAAGAATGGAG GATATTGTGAGTGCTCCATTGGCA GTTGAAGATGCCCTTGTTGGTCTT TTTGACCATAGCGATCACACCCTT CAAAGGCGTGTTGTTGAGACCTAT GTTCGAAGATTATATCAGGTTTTT ACCTTTCATTTCTGCATCAACAGA GTTGTCAATTTGTTGTCATAGAAA ATTGAAGGTGTTTGATCAGATTGT TTTAAATAAAATGTGGTTTAATATA TGCATACATCTTTAAAAAAAGAAA CGACATGTATTTATTGGTAAAAAA CTAAAACATCAAATCAAGTGTGGA TTTTATACTGTTTTTTACAAAACTT TGTAAACTGATTATATGTTGTTTAC TTGAACAGATAAATGTTTTAAACTA TTAAGAATATTTAAAAGATGGAATA AGAATAAATTTAAAGTCATTTCTGA GTTGTGGCCCTTGAGAATAGCTGT TCATGTAGTTAGTAGACCTATTTG ACTTTTTTCTAAAATGTATACTACA CTGTTTATTAATGCCTACTCAAAT GAATCGGGTTGTCTAAAATAAAAC ATCACTTATAACAACAATAAAAGA AGCAAAGCAGTCATTTTAGTTTGC ACTTTTGCAATTCTCTTGGTAGGA AGAAATCTAATATGATTTTAACTGA CCATGCTTCTCATATCTGTATCAG CCATATCTCGTGAAGGGGAGTGT TAGAATGCAGTGGCACAGATCCG GACTCATCGCTACATGGCAATTTA TAGAAGGACTCATTGGAGAAGTTA ATGTGCCTGACTATGAACAGAATG AAGCTCCCTTGGAAGACAAGAAAT GGGGAGCTATGGTTATTATTAAAT CTCTTCAATTTTTGCCTGATGTCAT AAGTGCATCTCTTAAAGAAACGAG TCATAACCTTCCCAGAACAAGTCA GAATGGGTTTGCTGGTCATAGTAA CCATGGTAATATGATGCACATTGC TTTGGCCGGCATAAATAACCAGAT GAGTTTGCTTCAAGACAGGTATGT GATGATAATGTTACATGAAAAGAT ACCATCAAACCTGCTTTATGATCT TTGTGTCATGCTCAAGAAACAAAA TAACTGGATAAATATAAAAACTGA GACCCATCATCATTCGATGATGCA TGCCATGTTAACAGTCGGTAGATT TGATGGCTTATTCATTAGCTGGTG ACATATATTTGCCCTGTTGATGTT ATGTTCACTTGTTATGTGATGAAC TGTAGTGGTGATGAGGATCAGGC TCAAGAGAGAGTCAACAGGTTAG CAAAAATACTCAAAGATAAAGAAG TAAGCTCGAGTCTTAAAAACGCAG GGTATGGAGTGATCAGTTGTATAA TACAAAGAGATGAAGGGAGAGGC CCCATGAGACACTCATTTCACTGG TCAGAAGAGAATCATTATTATATT GAAGAGCCATTATTGCGTCACTTG GAGCCTCCATTATCGACATATCOTT GAACTGGTTTGTGCTCAAAAGACC CTTCATAATTTTTCAATTCATTAAT AATATTATAATACTAATGAAGTTGT AAATGTATTGCTTATGCAGGACAA ACTTAAGGGCTATGATAATATAAA GTACACTCCGTCGCGTGACCGTC AATGGCACATGTATACTGTTGATG CTAAACCACTTCCGGTACAAAGAA TGTTTCTTAGAACTCTTATAAGGC ATCCAACAAAGGAATGGTTCTCGC CCTCAGGTTACCAAGGTTCAGAA GATGAGGGCCCACGGTCTCAGTT AAATCTCCCTTTTACATCAAGGAG CATCTTGAGATCATTAGTGACGGC TATGGAGGAGTTGGAACTTCATGT TCATAATGCTACTGTCAAGTCTGA CCATGCTCATATGTACCTATATGT ATTGAAGGAGCAACAAATTGGTGA TCTTGTTCCATACACAACGTAAGT ATTCATGTCATCTTCATGAATTTTT TTTTATCATATGCACTCATTTAACA ATGGTAATATGTTGTGAACAGGAG AGTGGATGTAGATTCTGGGACAG AAGATTGCGTGGTTGAGACACTTT TGGTAAGGCTGGCTCGTGAAATC CATTCAATGGTTGGTGTAAAGATG CACCGGTTGGGAGTTTTTGAGTG GGAGGTGAAGCTTTGCATGGCAT CATCGGGTCAAGCCAACGGTGCG TGGAGGGTTGTGGTCACAAATGT GACTGGTCATACCTGCGTTGTGC ATGTAAGTCATTAGATAGGATTAT AGACATTTCAGCAATACCCCTCAA ACATGCTTTTACCTAAAGTCAATT GCTGCAATTTTGATTTAGGTATAT CGTGAACTGGAAGATACTGGTTTG CACAAGGTGTATCATGCTACCTCT ACATTGGGTCCTTTGCATGGCGTA CCTGTGAATACACCCTTTCAGCCT TTAGGATTACTTGATCAGAAGCGT CTTTTGGCAAGGAAAAGCAATACT ACGTACTGCTACGACTTTGCACTG GTATAACTATCATTTTGCTCTTTCA ATGCTTGATGGTCACCTAAATTTG ATTGTACAGAAACACTTATTACCA TATCTATATTTCCAGGCATTTGAA GCAGCTCTTGAGAATATCTGGGC GTCGAAAGTCGTAAGTGATAGCA GGCCTAAGGGTAAACTTGTGAAT GTGACGGAGCTCATGTTTGCTGA GCCAAGTGGCTCATGGGGAACTC CCCTTGTTGCAGTAAATCGTGAGC CAGGGCAAAACAAGGTGGGCATG GTGGCGTGGACTATGGACCTCTG CACTCCTGAGTTTCCTGATGGAAG AACGATTTTGGTAGTAGCAAACGA TGTTACGTTCAAAAATGGATCTTTT GGTCCTCTTGAGGATGCCTTTTIT GAGGCAGTTACTGATCTCGCTTGT GCCAAGAAACTGCCACTAATATAC TTGGCAGCAAACTCGGGGGCCCG TATCGGAGCGGCTGAGGAAGTCA GATCTTGCTTTAGAATTGGGTGGT CTGATGAGTCGACTCCTGAATCG GGATTCCAGTATTTGTATCTTACT CCTGAAGATTATACCCACATCAAA TCATCTGTAATAGCTCATGAGGTT CATCTATCAAATGGCGAAACAAGA TATGTCATCGATACTATTGTGGGA AAAGAAGACGGACTCGGGGTTGA AAATTTGAGTGGTAGCGGGGCAA TTGCTGGTGCCTATTCGAAAGCAT ATAAGGAAACGTTTACATTAACAT ATGTTACTGGAAGAACAGTTGGGA TAGGCGCATATCTGGCACGTCTT GGGATGCGGTGCATACAGCGGCT TGATCAACCGATTATATTAACGGG TTTTTCTGCACTGAACAAGCTTTT GGGCCGAGAGGTTTATAGCTCAC AGATGCAACTAGGTGGGCCTAAA ATTATGGCTACGAATGGTGTTGTC CATTTAACGGTGTCCGATGATCTC GAAGGTGTCTCAGCTATCTTGAAT TGGTTGAGCTTTGTTCCACCTTAT GTCGGTGGCCCACTTCCTGTTTTA GCACCTGTGGATCCACCAGAAAG GCCCGTTGAGTACCTCCCTGAAA ACTCATGTGATCCTCGGGCAGCT ATTTGTGGGGTCGTGGATAGCAA CGGTGAATGGGCTGGTGGGATTT TCGATAGAGACAGTTTTGTGGAGA CATTGGAAGGTTGGGCGAGGACA GTCGTAACGGGTCGTGCCAAACT TGGCGGGATCCCAGTCGGGATCG TTGCTGTTGAGACACAAACAGTGA TGCAAGAAATACCTGCAGATCCC GGGCAGCTTGATTCACACGAACG TGTTGTTCCTCAAGCAGGTCAGGT CTGGTTCCCGGATTCCGCCAGCA AAACAGCTCAGGCATTGATGGATT TCAACCGAGAAGAGCTCCCACTTT TCATCATGGCTAACTGGCGAGGC TTTTCTGCAGGTCAGCGGGATCTT TTTGAAGGGATTTTACAAGCAGGG TCAACAATTGTTGAGAATCTCAGA ACATATAACCAGCCTGTTTTTGTA TACATCCCGAAAACTGGAGAACTT CGTGGCGGEGTGCATGGGTEGGTTGET CGACAGTCGAATCAATTCAGATCA TATAGAAATGTATGCAGAAACCAC AGCAAAAGGAAATGTCCTTGAACC TGAAGGTATGATTGAGATTAAGTT CCGAAACAAAGAATTGATAGACTG TATGGGTCGTCTAGATCCACAGAT TCGAAGCCTTAAAGAAAGACTTCG AGAAACAAAGTACGATCAAACGAT CGTCCAACAGATAAAATCTCGTGA AAAACAGCTTTTACCGATTTACAC TCAAATTGCTACCAAATTCGCTGA ACTTCATGACACATCATTGCGAAT GGCTGAAAAAGGTGTGGTCAAAC AAGTTGTTGACTGGAAAGTATCTC GGTTTTTCTTTTACAAAAGGCTTC GTCGTAGGCTCGCAGAGGCTTCC TTGATCAGTAGTGCTCGTGAAGCT GCTGGTGATACTCTTTCCTACAAG TCTGCTCATGAGTTGATTAAGAAA TGGTTTTTGGAATCGAAAACTGAA GATTTATGGCTTAGTGATGATGCT TTTTTCACTTGGAAAGACAATCTG ATGAACTATAATGACAAGTTAGCC AAGCTACGTACTCAGAAGCTCTTG GATCAGTTATTAAAGATTGGTAAT TCACCATTGGATCTACAAGCTTTA CCACAAGGCCTCGCCGCACTTTT GCAAGAGGTGAACAAACTCTCTTT TATTTTCCCTTAGAACTATTTAATT TAATTATCTATGAATGCGCAAAAA CAACAGTTTTATTTAAATATTITTC TTTCACTATGCTGCAGGTGGATCC AGTGACCAAAAATAAACTAGTCGA AGAACTCTTGCGCGTAATTAAGTA GGTAATTATACACAAAGCTCATCA GATTCTTTCTTTGTTTGTCAAAGTG AGAAGCCTTTTGAGCAGTGTACAT TATAAGTAGGTGTCATAAGAAAAC AGGCTCAAAATAGTTTAAAGTATA TGAGGTTTACCATGTTCAGATTGT TTTATTTTTCTTCATAAATTGTATA ATACCATCACATTTCTATCGCATTT TTTATATATCTATATATAAATGGTC ATTTITITTATTTTATTITTATTITTATA AAAGGTTCTCTTTGACCATCTTTG TGTTTCCTTTTGGCTCTTCTTGTC CATCTTCAGTTCTTCTCCTTCCOTTC GCTTTCTTTTCGTCTCTTGAGTTAT CTTTTCTTTATCTTCTCATCGTGTA CGGATTACGTTGATATGAGCACAT ATGGCAAAGTTGATTCAGATAACT CCACAACAAATTTTCACTTGATTIT TGAATGTTTATAAGCTTACAATACA TCCATGCACTCATGTTCATCTGCT AAATGTACTAGTACATAATCAAGT TAAAAACTTCAACCCAAGAACACT ATTCCACTAAAAATTTCGGCATGA TCTCATCATAAAATCTACAATCATT GTTTATTGTCAACCATCAAAGACC TGTAGAATACTAATGAACAATTGC AACAAGTGAACAGTTTGCCCCTTG TTACCGTTGAATGAATATTTCAAA GATCATGATCGAGCCTCGATCTTG ACCAGCACTGAAACATTATAAAAA CAACTTCCATTTTAAATGTTTGTCT AATATAGGGAAGTGAGAGTCAGG TAGCCCACAATGTTTTAGACCCCA GAGCTACTTGTTCTGGCTGTGGG GTTAAATATAGTTATATAGACTTAT GTTAAGTGCAGGCATTACACACTT TTTTGCATTATATGTTTACGCGCA GATATATGTATTTGTGACCAGTTA AACCGGTGTGCTTCTCTTITCITGT GTAATGAGCTCTGTTATGCAGTTT CGGGTTTGAGTCGCTTTGTGATAA TTTTGTATGTGTTACTGGCCCGGC CAGATAAATGATCGGTTGATATAG GCTGGTTCTAGTCACACTAGACG CTGATTAGTGGTTAGGCTTCGATG TATAAATCAAAGTTATAGCTACATT CAAATCATTATTATAATTATTTCTA TTTCATTCAAAGTAGGAAGATTAT ATCATACATAAATATGACACACAG GATGAATTTCATAAACTTCAATTCT ACTTTTCATTAAAAGCTTAATTTAT CTAGTTGCCCGGTTTCCCATTCOTT CTTCCCGTTGCCGCCACCAGGCC TTTTACTCCACCATGGCCACCCCC TCCTTCCCCAACCACCAAATGGAT ATCCACCCCAGATACCTGGCCAT CCACCACCTGGCCAAAATCCGCC ACCAGGAAAATATCCACCACCTG GCCAATAACCCCCATAATACGGAT ATGATGGGTCATAGCCCCCTCCAT ATCCTTTACCTCTTCCTGGTCCAC CGTACCCTCCATATCCATCACOCG AATCATAACCTCCCCCTCCACCAT ATCTGCCACCATGATCTTTTCCAC GTCCTTCATCATAACCACCATCOTT CTCCACCATGATCTTTTCCACGTC CTTCATCGTEGTCCCCOTTTGCCOTT CATGATCACCATCTTCACCACCAT GATCTTCTCCAGGTTCATCATCAT CATGGTCATCGCCTTTTCCCCCOTT CATCACCATGATCTCTTCCTGGTC CATCTTGTCCACCACCTTCATGAT CACCACCTTCATCACCATGATCTT GTCCAGGTCCATCATCATCATGGT CACCACCTTTTCCCCCTTCGCCAC CATGATCTCTTCCTGGTCCATCTT GTCCGCCACCTTCATGAT-
CACCGCCTTCACCA 50 Conyza |gD- [17803 | CATAATACTCTTACACCCCTACCOT canaden- | NA- TCTTTCTAATCATTACACGCTCTC sis Con- CTCGACCTTCTATCACCCOTCCGCC tig GCCGCCCTCCTTCTCCACCOACCOG
CCCTCGATCTCCACCACOGCCOTC CCTTTTATATTGTCATCGCCTTTTA GCCGTTGCAACGCGCGGACACTA TGCTCGTATTAAMAAGTAGTAACGT AATAAACATAAAGTTTACGTAAAG TTTATATATTTCATTATTTTGTTATG ATTTTGTACTGATGAATATATATTT AAGCTAAAATCATTCACTCTAGAG TGTAAGTCGAACGGGTCCAAACT GAACTAAACTATTTGTCTATGGTA GTCAAATTCTTAATCTTTTTGGTAT CGATCGTTGTGTAGTGTTGCACAC CTCACTTGATATTAGTTTTATGTGA TTATATATGGTTAATTTAATTTTITTC TTTGATTTTTGATCATGGTCTTAAA TATCATTAAAGGTGAAGAAACATG TGAAGAGGGATAAATTTGGAGAAA GAATGGCATCACTAAAACAGATAG TGTCACCCTATGGCAAGGTTAGTC CTTCTTTAAGTTTATTAATTATATG TAATTTGTTTGATTAGGTATATCAT ATATGTATACTAGTTGTTTTGATTT CCAATCTATACAAGTAGGATTTTG CTAAACATAGTTGTAAGGGTTATA GTTACAACACAATAGAATGGTATA CATACATTATATATATATAAAGATA TATAACTGTTTATTAATAATAATCT TTAACCGTCATGTAAACCAATTTA CTTTGCTTTATCCATATCCTTAAAG GCTATGAATAGCATAGTCGATGTA AGTATATGGTTGCTTAGACGGTGT GTTAATGTTGATCGTACAGGAGTC TAGACTTGGACCATTGTGTTTTAG AGAAGAAGGGAATCGAACGCAAA GGTAAAACTTCCTTTATTTTTAAGA GCATAGTTATAATATCATTCAAATT TAACCAACAATTTCTGTTACATACA TCGAAATAGGCTTGATTACTCATA CCTATAGAGATGAGTGACATGTGT GTATGAAGATTTATATATTGAATTG TAGGATATCATTTTCCCATTTCTAA TGTACTAGTTAATTATGGTTTGCG GTTTITTITTCTTTGTTGTATGTCCAT TACAAAATTACAGTTGGACATCTT CTTGGTGGAATTCAGATGATATAA AATAGTTAATTTTACCAAACACTAC ATCATTGGTAGAGAGAAATTAGAA CGTAGATAAATGGTTTGTAAGTTT CAAAAGAGATACTCGTATTACATA AAATGTTGTCTTTTGCAATTCGCA GATTTCCAATTACAACAGATTTGA CACAATGTTCTATTATTTGTTAATC CAACCATGAACCACTAATAAAACA GTACAAACATCTTGAATAAAAAAA AGCCACCAATACATTATTGATTGT TGTATGCTTTTTGTCTCCATATAAT GACCAGTAATATCAAAAAACATGT ATTTTATTCTTATTCTAGCTTAAAA AGGTTCAAAAATGCACATCCAACT TTCTCTCTTCTTTCCAATCATAGCOT TTTCAAATTAAAAGCATACACGTA AAAGAAACATATGGATGTAGATTG ATATGTGTGTGGGGGGTAGTTGGÇ TTAACCATGTCACGTGCTCTGCAT CACCTCCCATCCTTGGACCCCAAT TTGTTTTTTGTACCTACTACATATT TAAGTAACTTTATGGCACCTCACC AAAAACCAACCAAACAAACCAAAC TCCCAACTATACATCACTTAATTG CACACACACATATACCTCAACAAG TACTTACATCTCTCCCAGATTTCOT GTCATTCCAATTTTCTTGTTTTTAA TCACAATTTTGTTGTTGTTGTCAAT GTCTGTCTCTTTTCAAACCAGCTA AAAAAAGAAGCAAATTCTTGATTT GATTCAGCTGTTGTTCCACTTGTT TATGGTTAGTCTTTCTCATTCTTTC ACCCCCCAAGTTTAAATCTTTGAG TTAATTTCTTCAAATTCCTGTGTTT TTTGAACCGGGTTTTTATCAGTTTT GTTGAGTTTAGCAAAAAAGTAGAG TTGGGTATGTAAAGATTGAATCTT TTTACTGGGTTTATGTAATTTCTTT GAAATTTATAAGTTTCTTGCAATG GGTATATGATTTTCTATTGATTGAA GTGGTTAATAACAGGATTTGGTGA GTAAAGTTTGAATCTTTCGAGTTA TGGATTTATGTCATACCTTTTCITG CCCTTCAAAATAAAGTCAAAGCTT TAGTTTTGTGATTTGACTTTGGTAT CCCTTCAAAATAAAGTCAAAGCTT TAGTTTTGTGATTTGACTTTGGTAT GCTGTTGCTCCCATGAATATTTTC ATGCTGTTTGTAAATTGTAATATAT ATTTTGATAAATTCAATTITTGTTAT ATTTGTTTCCTGATAAAGTTTTAAT GTGATTAGTGATTACTTCAATTTG ATGAGTTCAATAATAATAAGAAATT TAGAACTTTGAACCTCGTAGTTCT AATTCGAGGTTTCCTAGCTCTATG TAAACCCCACTATATTCTCCATTAT AACATACGTTTATGTGTTACTTTAT TTAGACATTTTAATATTGACTCAAT TATAACATAGGTTCAGCTGAAAAT TTAATTTCTTTGTTAGTGAATTGTT GTGACTTTTITITITGGTAGTTTGC GTTGTGATAGTCAGGAGACAGAA AGGGCAATTTGTTTCTGTTCTITTIT AAGTTAGATAGGTGACCATTTCGG TAGATACTAGATAGTGCAAAGATA TAGTGTTTTTTGTAAGTACCAAGT ACTTTATGAACTTACCCAATGATA ACAACTTTTGATGGTTCAGTGGTT CAGCCTTCTCTTTGTCCCTAGACT AATTAGTCCAATCTATCTCTCAGT ATATATTTTTTAGGTATTGACATAT TTTATGATATTGGCAAGTTGGTAG TTTACTTTCAACTTTTAAGCAATAT ATGGACATATCCACATATATCAGT TCCATATTACTAGCATGTATCCTAT TCTGGGTTAGTATGCTACAAAAAG GGTTTACATGTCAAATGCAGAATT GTTCAAAGAAAACGAGTTGTTAGA CCTAATAAGTCAAAGTAATGCTTA CTCTACACTTTGCTTACTGTTTGG CAGTGGCACCATGTCAGAAGCTC AAAGAATGCTTCTAAGTGGAAGTT TCAATTATTATGGTAATGGCATTG TAAATGGGGCGATTTCACTGAGGT CTTCTGCTAGTAGATCTGCAATTG ATGAATTTTGTAATGCACTTGGAG GCACCAGGCCAATCCAAAGTATTT TAATTGCAAATAATGGAATGGCGG CTGTAAAGTTTATAAGAAGTGTGA GGACATGGAGTTATGAAACATTTG GCTCAGATAAAGCTATTTTGCTGG TAGCCATGGCTACACCGGAAGAT ATGAGGATAAATGCCGAGCATATT AGAATCGCTGATCAGTTTGTTGAA GTCCCTGGTGGTACAAATAATAAT AATTATGCGAATGTGCAACTCATT GTAGAGGTATGTAGCTTATATACG TGGATCCTACATCATGATTTATAA GCTTTAAAATGATCTATTTTATGAA ACATTGTGCATTTAATGATGCCTG AAAAGATTATGTTTCCAAGACTTAT TTTGCTTAACTTGTTGGATCAAAAT GTTGATCTGCTTCCATGAATATAG TAATTCGAATATGTTGGTTTAATCT TCACTTTCAAAAAAAAAAAAAAATA CTTTCAACTTTTTATGTTAGCATTG AGTTTGAATCTCAAGAGAACTTAT TTCACTTTTGAAATCGATATGGAT GTGTTGAACATGTAATTGATAATC AGCAACATTTTAAAATTTATTAGAA AATGACGAGGGATGCCTCTTCAG GCTACGCGGCGAGCCTTTGGCTC TAATGTAAGCGGCCTAACCGGTAT ACCCGGGTCTCTTCTGAGATCOTTT GGGTCACCTTACCACTAGACCCC CTTGGAGAAGGTTTTAAAAAGTAT TAGAAAGTATATAAATATAAAATAG AAACGATATGTAAAATTTAAAAAAT ATGTTTCATTGAGTTATCTTACACC TGACTATTTGATATTGAGCATTAAT ACGAGTTTGATGGAAAATATAAAA TAATTAATATTTAGCTATCATCATC AATTCCTTTAAAATGGTTCATTTAT GATTTATGACTTCAGACTGCTGAG ATAACACATGTTGATGCTGTTTGG CCTGSGTTGGGGCCATGCATCCGA AATCCCTGAGCTGCCTGATGCATT GGAAGCAAAAGGTATTGTATTTCT TGGGCCACCAGCTTCCTCCATGG CAGCTTTAGGTGATAAAATTGGTT CTTCTTTGATTGCACAAGCTGCTG ATGTACCGACACTTCCTTGGAGC GGTTCTCATGTAAGATTTTTTTTAC TATTGTAGTCTTTGTCACATCAAC AATGATCCTTATACTTTTAACTCCA TAAAGATTGCATCGTTCTATCTCA TATTCTCTATAATCTAAAAAAATTC TATATTCCTCTTATTTGTGAAAAGT CTGAACTTCATAACAAAATCACAT CTTGTACCTCTTATATATTAAACTG CATCTTTATGCCTCTAATTTATTGG AAACAAGATCTTTAAATCCTTTAAA GGTTGCATCTTTATACCTCTTATTC TGTAGAAATTACATTTCATACCACT TGTTCTTTGCAATTTCGCATAGAT ATTAATGCCTACTCTTTAAAAGATA CATTTTCTACTTCTTTACCTCTATA ATCACATCTTTGTACCTTTCACCT CTCCAGTCTTCTTACTCTCTACAG TCACATTTTTAGGTAAAAATTCCTG TGGATAGCTGTTTGGACACACTCC CGGATGATGTATATAGAAAAGCGT GTGTGCATACAACAGAAGAAGCA ATTGCTAGTTGTCAAGTTGTTGGT TATCCAGCAATGATTAAGGCATCA TGGGGTGGAGGTGGCAAAGGCAT AAGAAAGGTTTGATTCTTTACAATT GGGAAATTATTTCTTCTCCTCAAA GTATACGGCAAACTTTTAAAACCA ATTACCTATTGAAACTTTAGGTGC ATAATGACGAAGAAGTCAAGGCA CTTTTTAAGCAAGTTCAGGGTGAA GTGCCTGGTTCCCCTATTTTCATT ATGAAAGTTGCTTCTCAGGTAGGA CAATGTTGTAATTGTTATTATTITTC CCAATTTCAACTCAAAACCCATTA TCATTATAATAATATGTTGATTTCT TGTATATACAGAGCCGACATCTAG AAGTGCAGCTACTATGCGATCAAC ATGGGAATGTAGCAGCTTTGCATA GTCGTGATTGCAGTGTTCAAAGG CGACATCAAAAGGTAAGTTCATGT TTGTCCTTTTTACTITCTITTITATC CTGTTTTGTAACTCTAATTTTATTT AATACTTGATATGTCAAGATTATTG AAGAGGGGCCAATAACCATAGCT CCACATGACACAATAAAGAAGCTT GAGCAAGCGGCGAGAAGATTAGC AAAGTCGGTTAATTATGTTGGAGC AGCCACTGTAGAGTATTTGTATAG CATGGAAACTGGAGACTATTACTT TTTGGAGCTCAATCCCCGGTTACA GGTGCTTGCAATTTCTGTITTTGTG GGTCCTAGTTATGTGTCCTAAGAA GTAAGATGAAATGGTGGGCTCCA AGATGGTTATGATTTGTTTTCTGA AGCTATGTATGTGGAACCTTTCTT TAGGTTGAGCATCCAGTCACAGA GTGGATAGCGGAAATCAATCTACC TGCAGCACAAGTTGCGGTTGGAA TGGGCATTCCTCTTTGGCAAATAC CAGGTTAGATATCAAAAGTTCGTT TTTTGTTGACTATCATAGTTGGTCT TTTGCTACAATGCAACCATCATGT CAACTATTTTCTTAATTTCTCTACA TGTCTTGTTGGCTTAGAAATAAGA CGATTTTATGGAATGGACAATAGT GGAGGATACGATGCTTGGAGGAG AACATCTGCTCTTGCAACTCCATT TGACTTTGACAAGGCAGAGTCTAT CAGCCCAAAAGGTCATTGTATTGC TGTACGTGTAACAAGTGAGGACC CAGATGATGGATTTAAGCCCACTA GTGGAAAAGTTCAGGTTTGGAAG CAGACTAACATATACCATATACCC CTACAAATATAATATATATCCTTTT TTTITTITITTITACCATATTGATCG AATTCCACTTTTAGGAGCTAAGTT TTAAAAGCAAGCCAAATGTCTGGG CATACTTTTCTGTCAAGGTACGCT GGGTTCAAACCTTTITITTITITITIT TGAACTTCCAATTGACATATTCTAA AATGTTTGAACATTGCAGTCCGGA GGAGGCATTCATGAATTCTCAGAT TCTCAATTTGGTAAAGACGACTGG ATCTTGTTTGGTTGAAATATCTTGA ATACTCACTTATTGGTGTAGTTCA AGTTTACATTCTTGGTCAAAACGT TCATGTTCTCATTTTAATTCTGTAT CTATCTTAGGCCACGTTTTTGCAT TTGGCGAGTCAAGACCTTTGGCTA TTGCAAATATGGTTCTTGGGCTGA AGGAAATTCAAATTCGTGGCGAGA TCCGTACGAATGTTGATTATACAA TTGATCTGTTACATGTGAGCATTT TGGGGTTTCACAGCTAACAAATTT CTTATTTTGTTTACCATAATGAGTT ACTTCATGGCGATATAAGGGGTG AGCCATGGAGCAAGTGCCATGTA TCTTAACAGATAAATTGTTATGTTC ATGTTTGGCGAGTACTTACACATT TGAGAATGTCGAGAATTTGATTAT ATTTCACCAAACGTTCTTATTGCTT CACCTAAAATGTGAACGTTTTCTT ACATGCTTAGTTTTTATTCCTTITITT CTATACTTGTAGGCTCCTGATTAT AGAGAAAATAAAATACATACCGGT TGGTTAGATAGCCGAATTGCTATG AGGGTTAGAGCAGAAAGGCCCCC TTGGTATCTTTCAGTAGTTGGGGG AGCACTTTACGTAAGTACAAAATA CCTCTTTCTTTCTATATTCGTCATT TTTAAAGTACTTTTACTTACCATTG ATGTTTGTTAACTTCAGAAAGCTG CTGCTAGAAGTGCAGCCATGGTC TCGGACTATGTTGGTTACCTTGAA AAGGGCCAAATCCCTCCTAAGGTT TGTCAGATATTTTAGTATTITITTT TAATTTTTAAGAGTTGGTTCTCGTA ATGTTTACATTGATGATCAGTATTT GTCTGTTTTCTTACTTTCAGCATAT ATCATTGGTCAACTCACAAGTTTC TTTGAATATTGAGGGCAGCAAATA CACGGTAAATAACAAGATAACTGC CTATCGTTATTCGTTCATAAAAATG GTTGTTCTTGAAGTTTTCTITTGTG TGTTTTTTITTCTTCTGATTITTITITOT TTTTATTTGTTAGATTGATATGGTA AAAAGAGGGCCAGGAAGTTACAG ATTGAGAATGAATCAATCCGAGAT TGAAGCAGAGATACATACACTACG TGACGGAGGCTTATTGATGCAGG TACTTAATCCATACGCTCTATTTITT CTTTCTATTTGGTTTATTCTGTCAA ATTTTCTTTTTATTTGGTTTATTCOT GTCAAAATTTCTTTTTATTTGGTTT ATTCCGTAGTTAGTTTGTGATTAA CTGATTACTATATTAAGTCATTGGT TGGTATGTATACATATAAAACTCG AATATAAGCATTTTAATGATGCCA AACCTATATGTAGTTTTACTCTTTA GGATTTCATGATATACCTAGGAAA TCCCTCGTGTCTTTGTGGCAGCTA GCAAGTTGAAGATTAATAATATCA ATAAAGAAATTCAGAGAATTTAAT GCAGCATGTTCTAAGGGAGTGTT CGGGGATGCATTCTGAAAATAATT ATGTGATATTTAGTAAAATTGCAAT TAAACGTGGTGCAAGAAATAGTGT TTGGATATGCTTCTGCTATAAAGT TCTGGCAATCGCTGTATTGAGTGT TTGACGGATTATGTCTATTTAAGA AGGTGGTAGATAAACTAAAAGTAT ACATGGTTAGTGGTGCTGTAAGCA TTTGCCATCAAAAAGTAGGTAGAT AAAGGAAGAGTGCTATAGGTAGTT TTATGCTACTTTTTGGTTATCGAGT TCGTTGCAGCTAGTATCAAACTAA TTCTTTAACTATCGTAGCTGTAATA GGTCACCCTGAACATTTCAATTTA TTGCAACCTTAAGTTACATCATTT GATAATCACGTTCAAGACACATTC TTATTTTATACTCTGATATCATATG ATTTGTGGTTGGTTGATTCAATGA TGTAGTTGGATGGGAATAGTCATA TATTATACGCCGAGGAAGAAGCT GCCGGTACTCGCTTGCTTATTGAT GGACGGACTTGCTTGCTTCAGGT GCGAACAACTAGTTCTTTTCITTGA ACTTTATTTAGAGGTTGCCATTTC AACCATTTATCTATGATGGGACAA TTTAAACAATGTTTTACCCTTAATG GTGTATTCAAATGGGTCAACAGTG ACCCAAAGTACATTCTCACTGGAG CAAACTGCCTGTATCATTTITITIT GTGAGGTTCATTGTTTTTGAATAA TATTGTGTTAATTTTCATATTTAGT AGACTAAAGTAATTATGTAAGTTG TTGTGAACCCGTTCGATCTGCTCA GGTTATACTCAACCGGTTGCAATC CTCCTAATTTGCCACCTTTACTATT ACTTACTATTTGGGTTACCTGTTTA TAGAATGATCATGATCCTTCCAAG TTGATGGCTGAAACACCATGCAAA CTTCTAAGGTACTTGGTCTCAGAT GATAGCCATGTTAATGCTGACACA CCGTATGCTGAGGTTGAAGTTATG AAGATGTGTATGCCACTCCTTTCA CCGGCTGCTGGAGTTATACAATTC AAGATGTCAGAAGGTCAAGCCAT GCAGGTTAGCATGTCACTTTTTCC CCATTTTTAAGAAGTATTTACATTG TTCAGTTTTTCCGAACATCCAAGA ATAAAGCTCTTGGTTCTATGTTTTT GCCAACTACTTACAGCTATTTATA TTTACATGTTAATAAAATGTTCTAT CGATTGACTTCTTGAGTCATTGTG CTTATCGCAACTCAATCTTCGTTA TTGTACAGTGATTTTTTAAATGTAA TACTGCCAACTTTTTGAATAAATC GTATCAAATGTAATCTTTAAGCTAT ATAACAAACATATGAATTTCGATTT CCAAATAATATCTACAGTTCACAA ACAAATGCTTGTTTCCTGCTTGTT AATACCATTTTTGTCTTCTCTAAAT CATACATACCAAAACCAAAATTGT TGATCATTTCTGATGAATATAAATC TTTGTATATGTAGGCTGGTGAGCT TATAGCAAGGCTAGATCTTGACGA TCCGTCAGCTGTAAGAAAAGCAG AGCCTTTCAATGGAAACTTTCCTC TTCTTGGGCCTCCAACGGCCATG TCAGACAAAGTGCATCAGAAGTGT GCTGCAACTTTAAATGCTGCTCGA ATGATTCTCGCAGGCTATGATCAT AACATTGATGAAGTAACTTGTTTG CCATTTACTGATTTCAAATTITCTG AAAGATTATTCTGTTAACAGTTCT GATCTTTGATCGTAGGTTGTGCAA AACTTGCTTCGTTGTCTTGATAGT CCCGAGCTTCCTTTCCTTCAGTGG CAAGAATGCTTTGCAGTTCTAGCA AATCGTCTCCCTAAAGATCTAAGA AACAAGGCAAATTGATATTTTACC CTTTTTITTITTCTTTTCAAGCAGTT AACATTGGGATTATTTTTCTAAATT CAATATGTTTTGTATATTCAGTTGG AATCCAAGTTTAAGGAGTACGAAG GAATTTCCACACAACAAACTATTG ACTTTCCTGCTAGAGTTCTACGGG TCATTCTTGAAGTTAGTTGTGATC AGTAGTTTTCTTTATAAGTCCTTTC TTTGATTTAAAGACATAATTTAGTT ATATGTTACCTTTGTAATGTTTTCG TTCAGACCCATCTTGGATCTTGCT CAGAAAAAGAAAAGGGAGCCCAA GAAAGGCTCGTTGAGCCATTAATG GGTCTTGTAAAGTCGTATGAAGG GGGAAGAGAAAGTCATGCACGTG GGATCGTTCATGCTCTATTTGATG AATATTTATCTGTTGAAGAGTTGTT CAGCGACAACATTCAGGTGCGTTT GTTAGGATCGCCGATCCAGTATTT TGGATTTTCGATAGGGCATGCACT TGCATTACCATAGTCAGTTTATATT TTATTTCATCTTGTTACACGACAAC AAAGTACCTTTTTTCAAAGTATAAA ACTGCACAGGTTATGTGCTCCCAA AGGGTTTTTTAATACTTTGATCTAT GTGGAAATGGTATAAGAGTTTTAA TCATTTTGACATTAATGTCTGGATA AATTTGTTACGGGTTAAACCAATC AATCTAAGCCAAACCAAAAGTTAC CTGCAAAAGCTATTACCTAACCCA CCCATTTTGCCACCTCTGTTGGTT TTCTTTAGGTCTACTAATGGTTATC GAGTAAATTATATTATAACATAAGT AGTAAACCAAAATCCTGTACCTTT TAGGCTGATGTAATCGAACGTCTT CGACAACTATACAAGAAAGATCTC TTGAGGATTGTCGACATTGTCCTT TCCCATCAGGTACACATGTTTITT GGTTTTTGTTCTCCCCTTTAATGT GTATTTTATACCGATCATTAATATA TGTCCATGCAGGGTGTTAGGAGT AAAAACAAATTGATACTACGGCTG ATGGAGCATTTGGTTTACCCCAAT CCGGCTGCEGTATAGGGAGAAACT GATACGATTTTCTCAACTTAACCA CACAAGTTATTCTGAGGTCATCAT CGTCATATATATACACTGTTACAAT TTTGATCATCTCAATCACTTTTCTG TTAGTACTGAGTTTATGTTAATTGA TTATTATTAATAGTTAGCACTGAAG GCAAGTCAACTTTTAGAACAAACT AAACTAAGTGAACTTCGTTCAAGC ATTGCGCGAAGTCTTTCTGAATTA GAGATGTTTACTGAAGAAGGTGAA AATATGGATACCCCTAAGAGGAAG AGTGCCATTAATGAAAGAATGGAG GATATTGTGAGTGCTCCATTGGCA GTTGAAGATGCCCTTGTTGGTCTT TTTGACCATAGCGATCACACCCTT CAAAGGCGTGTTGTTGAGACCTAT GTTCGAAGATTATATCAGGTTTTT ACCTTTCATTTCTGCATCAACAGA GTTGTCAATTTGTTGTCATAGAAA ATTAAAGGTGTTTGATCAGATTGT TTTAAATAAAATGTGGTTTAATATA TGCATACATCTTTAAAAAAAGAAA CGACATGTATTTATTGGTAAAAAA CTAAAACATCAAATCAAGTGTGGA TTTTATACTGTTTTTTACAAAACTT TGTAAACTGATTATATGTTGTTTAC TTGAACAGATAAATGTTTTAAACTA TTAAGAATATTTAAAAGATGGAATA AGAATAAATTTAAAGTCATTTCTGA GTTGTGGCCCTTGAGAATAGCTGT TCATGTAGTTAGTAGACCTATTTG ACTTTTTTCTAAAATGTATACTACA CTGTTTATTAATGCCTACTCAAAT GAATCGGGTTGTCTAAAATAAAAC ATCACTTATAACAACAATAAAAGA AGCAAAGCAGTCATTTTAGTTTGC ACTTTTGCAATTCTCTTGGTAGGA AGAAATCTAATATGATTTTAACTGA CCATGCTTCTCATATCTGTATCAG CCATATCTCEGTGAAGGGGAGTGT TAGAATGCAGTGGCACAGATCCG GACTCATCGCTACATGGCAATTTA TAGAAGGACTCATTGGAGAAGTTA ATGTGCCTGACTATGAACAGAATG AAGCTCCCTTGGAAGACAAGAAAT GGGGAGCTATGGTTATTATTAAAT CTCTTCAATTTTTGCCTGATGTCAT AAGTGCATCTCTTAAAGAAACGAG TCATAACCTTCCCAGAACAAGTCA GAATGGGTTTGCTGGTCATAGTAA CCATGGTAATATGATGCACATTGC TTTGGCCGGCATAAATAACCAGAT GAGTTTGCTTCAAGACAGGTATGT GATGATAATGTTACATGAAAAGAT ACCATCAAACCTGCTTTATGATCT TTGTGTCATGCTCAAGAAACAAAA TAACTGGATAAATATAAAAACTGA GACCCATCATCATTCGATGATGCA TGCCATGTTAACAGTCGGTAGATT TGATGGCTTATTCATTAGCTGGTG ACATATATTTGCCCTGTTGATGTT ATGTTCACTTGTTATGTGATGAAC TGTAGTGGTGATGAGGATCAGGC TCAAGAGAGAGTCAACAGGTTAG CAAAAATACTCAAAGATAAAGAAG TAAGCTCGAGTCTTAAAAACGCAG GGTATGGAGTGATCAGTTGTATAA TACAAAGAGATGAAGGGAGAGGC CCCATGAGACACTCATTTCACTGG TCAGAAGAGAATCATTATTATATT GAAGAGCCATTATTGCGTCACTTG GAGCCTCCATTATCGACATATCOTT GAACTGGTTTGTGCTCAAAAGACC CTTCATAATTTTTCAATTCATTAAT AATATTATAATACCAATGAAGTTGT AAATGTATTGCTTATGCAGGACAA ACTTAAGGGCTATGATAATATAAA GTACACTCCGTCGCGTGACCGTC AATGGCACATGTATACTGTTGATG CTAAACCACTTCCGGTACAAAGAA TGTTTCTTAGAACTCTTATAAGGC ATCCAACAAAGGAATGGTTCTCGC CCTCAGGTTACCAAGGTTCAGAA GATGAGGGCCCACGGTCTCAGTT AAATCTCCCTTTTACATCAAGGAG CATCTTGAGATCATTAGTGACGGC TATGGAGGAGTTGGAACTTCATGT TCATAATGCTACTGTCAAGTCTGA CCATGCTCATATGTACCTATATGT ATTGAAGGAGCAACAAATTGGTGA TCTTGTTCCATACACAACGTAAGT ATTCATGTCATCTTCATGAATTTTT TTTTATCATATGCACTCATTTAACA ATGGTAATATGTTGTGAACAGGAG AGTGGATGTAGATTCTGGGACAG AAGATTGCGTGGTTGAGACACTTT TGGTAAGGCTGGCTCGTGAAATC CATTCAATGGTTGGTGTAAAGATG CACCGGTTGGGAGTTTTTGAGTG GGAGGTGAAGCTTTGCATGGCAT CATCGGGTCAAGCCAACGGTGCG TGGAGGGTTGTGGTCACAAATGT GACTGGTCATACCTGCGTTGTGC ATGTAAGTCATTAGATAGGATTAT AGACATTTCAGCAATACCCCTCAA ACATGCTTTTACCTAAAGTCAATT GCTGCAATTTTGATTTAGGTATAT CGTGAACTGGAAGATACTGGTTTG CACAAGGTGTATCATGCTACCTCT ACATTGGGTCCTTTGCATGGCGTA CCTGTGAATACACCCTTTCAGCCT TTAGGATTACTTGATCAGAAGCGT CTTTTGGCAAGGAAAAGCAATACT ACGTACTGCTACGACTTTGCACTG GTATAACTATCATTTTGCTCTTTCA ATGCTTGATGGTCACCTAAATTTG ATTGTACAGAAACACTTATTACCA TATCTATATTTCCAGGCATTTGAA GCAGCTCTTGAGAATATCTGGGC GTCGAAAGTCGTAAGTGATAGCA GGCCTAAGGGTAAACTTGTGAAT GTGACGGAGCTCATGTTTGCTGA GCCAAGTGGCTCATGGGGAACTC CCCTTGTTGCAGTAAATCGTGAGC CAGGGCAAAACAAGGTGGGCATG GTGGCGTGGACTATGGACCTCTG CACTCCTGAGTTTCCTGATGGAAG AACGATTTTGGTAGTAGCAAACGA TGTTACGTTCAAAAATGGATCTTTT GGTCCTCTTGAGGATGCCTTITTIT GAGGCAGTTACTGATCTCGCTTGT GCCAAGAAACTGCCACTAATATAC TTGGCAGCAAACTCGGGGGCCEG TATCGGAGCGGCTGAGGAAGTCA GATCTTGCTTTAGAATTGGGTGGT CTGATGAGTCGACTCCTGAATCG GGATTCCAGTATTTGTATCTTACT CCTGAAGATTATACCCACATCAAA TCATCTGTAATAGCTCATGAGGTT CATCTATCAAATGGCGAAACAAGA TATGTCATCGATACTATTGTGGGA AAAGAAGACGGACTCGGGGTTGA AAATTTGAGTGGTAGCGGGGCAA TTGCTGGTGCCTATTCGAAAGCAT ATAAGGAAACGTTTACATTAACAT ATGTTACTGGAAGAACAGTTGGGA TAGGCGCATATCTGGCACGTCTT GGGATGCGGTGCATACAGCGGCT TGATCAACCGATTATATTAACGGG TTTTTCTGCACTGAACAAGCTTTT GGGCCGAGAGGTTTATAGCTCAC AGATGCAACTAGGTGGGCCTAAA ATTATGGCTACGAATGGTGTTGTC CATTTAACGGTGTCCGATGATCTC GAAGGTGTCTCAGCTATCTTGAAT TGGTTGAGCTTTGTTCCACCTTAT GTCGGTGGCCCACTTCCTGTTTTA GCACCTGTGGATCCACCAGAAAG GCCCGTTGAGTACCTCCCTGAAA ACTCATGTGATCCTCGGGCAGCT ATTTGTGGGGTCGTGGATAGCAA CGGTGAATGGGCTGGTGGGATTT TCGATAGAGACAGTTTTGTGGAGA CATTGGAAGGTTGGGCGAGGACA GTCGTAACGGGTCGTGCCAAACT TGGCGGGATCCCAGTCGGGATCG TTGCTGTTGAGACACAAACAGTGA TGCAAGAAATACCTGCAGATCCC GGGCAGCTTGATTCACACGAACG TGTTGTTCCTCAAGCAGGTCAGGT CTGGTTCCCGGATTCCGCCAGCA AAACAGCTCAGGCATTGATGGATT TCAACCGAGAAGAGCTCCCACTTT TCATCATGGCTAACTGGCGAGGC TTTTCTGCAGGTCAGCGGGATCTT TTTGAAGGGATTTTACAAGCAGGG TCAACAATTGTTGAGAATCTCAGA ACATATAACCAGCCTGTTTTTGTA TACATCCCGAAAACTGGAGAACTT CGTGGTGGTGCATGGGTEGGTTGET CGACAGTCGAATCAATTCAGATCA TATAGAAATGTATGCAGAAACCAC AGCAAAAGGAAATGTCCTTGAACC TGAAGGTATGATTGAGATTAAGTT CCGAAACAAAGAATTGATAGACTG TATGGGTCGTCTAGATCCACAGAT TCGAAGCCTTAAAGAAAGACTTCG AGAAACAAAGTACGATCAAACGAT CGTCCAACAGATAAAATCTCGTGA AAAACAGCTTTTACCGATTTACAC TCAAATTGCTACCAAATTCGCTGA ACTTCATGACACATCATTGCGAAT GGCTGAAAAAGGTGTGGTCAAAC AAGTTGTTGACTGGAAAGTATCTC GGTTTTTCTTTTACAAAAGGCTTC GTCGTAGGCTCGCAGAGGCTTCC TTGATCAGTAGTGCTCGTGAAGCT GCTGGTGATACTCTTTCCTACAAG TCTGCTCATGAGTTGATTAAGAAA TGGTTTTTGGAATCGAAAACTGAA GATTTATGGCTTAGTGATGATGCT TTTTTCACTTGGAAAGACAATCTG ATGAACTATAATGACAAGTTAGCC AAGCTACGTACTCAGAAGCTCTTG GATCAGTTATTAAAGATTGGTAAT TCACCATTGGATCTACAAGCTTTA CCACAAGGCCTCGCCGCACTTTT GCAAGAGGTGAACAAACTCTCTTT TATTTTCCCTTAGAACTATTTAATT TAATTATCTATGAATGCGCAAAAA CAACAGTTTTATTTAAATATTITTC TTTCACTATGCTGCAGGTGGATCC AGTGACCAAAAATAAACTAGTCGA AGAACTCTTGCGCGTAATTAAGTA GGTAATTATACACAAAGCTCATCA GATTCTTTCTTITGTTTGTCAAAGTG AGAAGCCTTTTGAGCAGTGTACAT TATAAGTAGGTGTCATAAGAAAAC AGGCTCAAAATAGTTTAAAGTATA TGAGGTTTACCATGTTCAGATTGT TTTATTTTTCTTCATAAATTGTATA ATACCATCACATTTCTATCGCATTT TTTATATATCTATATATAAATGGTC ATTTTITTATTTTATTTTATTTITATA AAAGGTTCTCTTTGACCATCTTTG TGTTTCCTTTTGGCTCTTCTTGTC CATCTTCAGTTCTTCTCCTTCCOTTC GCTTTCTTTTEGTCTCTTGAGTTAT CTTTTCTTTATCTTCTCATCGTGTA CGGATTACGTTGATATGAGCACAT ATGGCAAAGTTGATTCAGATAACT CCACAACAAATTTTCACTTGATTITT TGAATGTTTATAAGCTTACAATACA TCCATGCACTCATGTTCATCTGCT AAATGTACTAGTACATAATCAAGT TAAAAACTTCAACCCAAGAACACT ATTCCACTAAAAATTTCGGCATGA TCTCATCATAAAATCTACAATCATT GTTTATTGTCAACCATCAAAGACC TGTAGAATACTAATGAACAATTGC AACAAGTGAACAGTTTGCCCCTTG TTACTGTTGAATGAATATTTCAAAG ATCATGATCGAGCCTCGATCTTGA CCAGCACTGAAACATTATAAAAAC AACTTCCATTTTAAATGTTTGTCTA ATATAGGGAAGTGAGAGTCAGGT AGCCCACAATGTTTTAGACCCCAG AGCTACTTGTTCTGGCTGTGGGGÇ TTAAATATAGTTATATAGACTTATG TTAAGTGCAGGCATTACACACTTT TTTGCATTATATGTTTACGCGCAG ATATATGTATTTGTGACCAGTTAAA CCGGTGTGCTTCTCTTTTCTGTGT AATGAGCTCTGTTATGCAGTTTCG GGTTTGAGTCGCTTTGTGATAATT TTGTATGTGTTACTGGCCCGGCCA GATAAATGATCGGTTGATATAGGC TGGTTCTAGTCACACTAGACGCTG ATTAGTGGTTAGGCTTCGATGTAT AAATCAAAGTTATAGCTACATTCA AATCATTATTATAATTATTTCTATTT CATTCAAAGTAGGAAGATTATATC ATACATAAATATGACACAGAGGAT GAATTTCATAAACTTCAATTCTACT TTTCATTAAAAGCTTAATTTATCTA GTTGCCCGGTTTCCCATTCOTTCOTT CCCGTTGCCEGCCACCAGGCCTTT TACTCCACCATGGCCACCCCCTC CTTCCCCAACCACCAAATGGATAT CCACCCCAGATACCTGGCCATCC ACCACCTGGCCAAAATCCGCCAC CAGGAAAATATCCACCACCTGGC CAATAACCCCCATAATACGGATAT GATGGGTCATAGCCCCCTCCATAT CCTTTACCTCTTCCTGGTCCACCOG TACCCTCCATATCCATCACCCGAA TCATAACCTCCCCCTCCACCATAT CTGCCACCATGATCTTTTCCACGT CCTTCATCATAACCACCATCTTCOT CCACCATGATCTTTTCCACGTCCT TCATCGTCGTCCCCTTTGCCTTCA TGATCACCATCTTCACCACCATGA TCTTCTCCAGGTTCATCATCATCA TGGTCATCGCCTTTTCCCCCTTCA TCACCATGATCTCTTCCTGGTCCA TCTTGTCCACCACCTTCATGATCA CCACCTTCATCACCATGATCTTGT CCAGGTCCATCATCATCATGGTCA CCACCTTTTCCCCCTTCGCCACCA TGATCTCTTCCTGGTCCATCTTGT CCGCCACCTTCATGAT-
CACCGCCTTCACCA 51 Conyza |gD- 16098 | AGTAGAGTCTAGATTAAAATTTCA canaden- | NA- TATACGATTGATATTATAAAGTGAA sis Con- TAATAGTAGCCTTGACGAGTCAAA tig GAGATATCACAGAGAGATATTAGA
ATCCGGACATTACTAACGGCATAG GATTAACGGAATTTGTGGTTTTAA AACAGTAATTATCTAAGAAATATG AAACAAGAAGTTATATATTCGAAT AAACTTGGATACAATAATTTGATTA CATGTTAGTTCAACCATAATCAAA TACTCGAAAGTCGTAATACACTAC CAATATCTTGATTCATATCATTTGC ATTGACTAAATCACTAAAATCATCA TTAAATTACAACAAAAATATTATGT ATTGGACTATTGGGGGTGGGGTGÇ GGGTAGGGTAGGGTAGGGGGTTT GGTTACCCATCTCACGTGGCATG CATCACCTCTCATATTATATGCAG GCATACTAAACAAACCAAATACCC AACAAAAAACACCCATATTTCAGC AATTCCAACTTTCTTGCAACAACG TTATTATTATTTTTATCTTGTAAATT CTTGATTGATTCAACTGCTTTTCC ACTTGTTCATGGTTAGTCTTTCTC ATTCTTTATATTTTGAAAAAAAGAT GATTTTTAGTGATTAAAGATTGAAT CTTTTTTCTAAGTTTATGTCATTTC TTGAAATTTTTGTGCTTCTAGAATT GGGTTTACTGTGTTATATGAATTT AATAAGTAAAAAAGATGATTTTAGT GATTAAAGACTGAATCTTTITTITCTA AGTTTATGTCATTTCTTGAAATTCT TGTGCTTCTTGAACTGGGTTTACT GTGTTATATGAATTTAACAAGTAAA AAAGATGATTTTAGTGATTAAAGA TTGAATTATTTTACTGGGTGTAAT GTCATTTCTTAAAATTCTTGTGTTT CTTGAATTATTATGAATTTAAGTAG TAAGTATACAAAAGATGATTTACT GGGGTAAAGGTTGAATCATTITTAC TGGGTGTTATGTCATTTTGTGAAA TACTTGTGATTTTTGAATTGGGTTT ACTGGGTTTTATGAATTCAAGTAG TAGTGCAAAAAAATGATGAAGAGG GTGTTGGAAAGATTAACTCATTAC TGAATTTAGGAAAGCCAAATAATG AGAGATTAGTGTTTGGCAGAACAA ATGAATTTTCTGGGTCTTGAACAT AGTTTGAAAAAGCATGCTGGGACA TGTTTTTCCAAAAATGCTATTTTGT AAACAAAATTTCAAACTCCTCCTTT GCAGTTAAAGATTGAATCTTTCTT ACCGGGTATATGTCGTTTCTTGAA ATTCGTGTCTTTCTTGAATTGGGT TTACTGTTTAACGATTAAACTTTGA GACTTTTTACTATGTTTATGTTAAT TTCTTTCTCTCAATGTTGTGATTTG ACTTTGGAATGCTGTCTAATTAAC TATAGTTTTGTTGATTTTGACATTT TTTTTGGCATATGGGTATGCATCT TAGGAGGATCTTTTATGTGTTTTG TTGGGTTACATTTGTTTGATAAGA TTTTGGATTAATCAAGTGGACATG ATGAAACTTTATGTGATGAAATAAT ATAAAAATCCCAATATAGAATTAAA CACAGAATTAAAAAGTAGATATGA TGCGCACATTCCGCCTTTTITGATC CCACAAGTAACTTTTAGATTGGAT CACTGACTATAAAATATTCCACAT CATTCTATAAAAAATCAGAATTCTG GATTATAAAATACACATTGGTATC CATTTTTTGAAGCACCAAAGTTTG ATCCCTTTGTGATACTTCATATTCA GTTTCACGTGGTTATTAATTTATTA TCTGAAATTGTAATTTTCATTTGAA TTCGCCTGTTTGATTTACAAAATTT GAGTTGCAAGTTCTGTTTTTATCC CCCTTAAGTTTGCTTCAAGAAAAT AGTTAAGATTATTAAAGAAGAAAA AACCCAGTTGTTTGACCATTTAGG AATTTAAGTAATGCTGAACTAAAC TTTGATTGGTCTACTTGGCAGTGG AACCATGCCAGAAGCTCAAAGAAT GCCTCTAAATGGAAGCCTTAATCT TGGTAATGGTTATGTAAATGGGGC CATTTCATTGAGGTCTTCTGCTAG CAGATCTGCCATTGATGAATTTTG TAATGCACTTGGGGGGAATAGGC CAATCCATAGTATTTTAATTGCAAA CAATGGAATGGCTGCTGTAAAGTT TATAAGAAGTGTGAGGACATGGA GTTATGAAACGTTTGGTTCAGAAA AAGCAATTTTGTTGGTAGCCATGG CTACACCTGAGGATATGAGGATTA ATGCCGAGCATATTAGAATTGCTG ATCAGTTTGTTGAAGTCCCAGGTG GTACAAATAATAATAATTATGCTAA TGTGCAGCTCATCGTGGAGGTAA GTATGGATCCGACACTCGTTTATT TACATACCACTAAGTGACTGACTT TATGAGCCGGGTCATATTTGGCTT TTTATCGCACATCAGCTGTAGCTG TTTTGTATATGCCGAAAGACCAGT ATATTGGGTGATCACTATCAATTTT CTTTAGAAGTTTGAGTTTGTGTCT GATTATTTCAGACTGCTGAGATAA CACATGTTGATGCTGTTTGGCCTG GTTGGGGTCATGCCTCTGAAATTC CTGAATTACCTGATGCATTGGACG CAAAGGGAATTGTATTTCTTGGGC CGCCGGCTTCATCCATGGCGGCOT TTAGGAGACAAAATCGGCTCTTCT TTAATTGCACAAGCTGCTGACGTG CCAACACTTCCTTGGAGTGGTTCT CATGTAAAATTTTCCACCATTGTTT TATTACTTTTACCATTACAGTGAG CTTGACACCTCTTATTTTTCAAAAT TGGAGATTAATGCCCCTCAGCTAT AAGAATTTGGATATTTATACCTTCT GATTTCCAACCAACATATCTATGT GTTTTTGAAAATCATACGTGTATCT ATACCTCTTACTCTTAAATAATCTA ATCCTTITTITITITCTITTGTTCAAAA TCACACAAATATGTTGCTCATTTG TCAAATTTATATCTTTCAGGTGAAA ATTTCTGCAGAGAGCTGCTTAGAC ACAATTCCAGATGACGTATATAGA AAAGCTTGTGTCCATACAACCGAG GAAGCAGTTGCTTCTTGTCAAGTT ATTGGTTATCCTGCTATGATCAAG GCATCATGGGGCGGTGGTGGCAA AGGCATAAGAAAGGTGTGCTTCCT TACATTTGAGAATAATTTTTATGTG AAGTTGTCAAAGGTGTAGAATGAA GTGATAACACATTAATCTGTAGGT GCATAGTGATGAAGAAGTCAAGA CACTTTTTAAGCAAGTTCAGGGTG AAGTCCCTGGTTCCCCCATATTTA TTATGAAAGTTGCTTCCCAGGTGA GAAAACATTCTAATATCTTTCTAAC CGTAATATGCATTTATCATITTITTC TTTCTAAAAGCATTTTTTGTCATTT ATCATTTGTTGTCGGAAAATAGAG CCGACATCTAGAAGTACAACTCCT CTGTGATCAGCATGGCAATGTAG CGGCTTTACATAGTCGGGATTGCA GTGTTCAAAGGCGGCATCAAAAG GTTCACCCAATTCAATTGTTTAATT CATTTTTTCCTTTITATCTTGTITTTT AATCTTTITITTITTGGATAATTTCA AGATTATCGAGGAGGGGCCAATA ACCATAGCCCCCCCTGACACAATA AAAAAATTGGAGCAAGCGGCAAG AAGATTAGCCAAATCGGTCAATTA TGTTGGAGCTGCAACTGTAGAGTA TTTGTACAGTATGGAAACCGGAGA TTATTACTTTTTGGAGCTCAATCC CCGTTTACAGGTGCAAGTGTTTTT TTTGGTGCTGTATATTGGAGGACA CTAGATGTGATTCATTCTCAGTCA TATCTGACACCTTTTTATTAGGTTG AGCATCCTGTCACTGAGTGGATA GCGGAAGTTAATCTACCTGCAGC ACAAGTTGCGGTTGGAATGGGCA TTCCACTTTGGCAAATTCCCGGTA ATATGTCAGAATAAGCCATAAATG TAATGAACGGTTGACAATTGTTGG CCATCATACTTGTCTACCTAGCAC TTGTCATTGAAATTTATAAAAAAGA CCTGTCTATTTAGGAGTATCTTTT GAACCTTTTITTCTTTGCTTTAGAA ATAAGACGGTTTTATGGAAAGGAA AACGGTGGAGGGTATGATGCTTG GAGGAGAACATCGGTTCTTGCAA CCCCATTTGATTTTGATCGCGCCG AGTCAGTTAGGCCGAAGGGTCAT TGTGTTGCTGTACGTGTAACAAGT GAAGATCCGGATGATGGTTTTAAG CCCACCAGTGGAAAAGTTCAGGT TTTTGAAAAGACTTATGCACCCTT ACGAAAATACCAAATATTATAAGT ATTGATTATATAGCATACTGATTGA CAACTTTTTAGGAGCTAAGTTTTA AAAGCAAGCCAAACGTATGGGCA TACTTTTCTGTCAAGGTACTCTTG TCTCCCATTTATAGACATTTATGTA ACTGCTTGATTGCCAAACTACATT TTTTTACTTGCTAACACCTTGGAC TCTTGCAGTCTGGAGGAGGCATT CATGAATTCTCAGATTCTCAATTC GGTAAAGGCCGAATCTTGTTTGG GTTCTGTTTAAATGTTTGAATCTCC AATTGTTAGCGTAGTTAAATTTTAT GAGAATCACTGCCAAGATGTTTTT TTCTCATTTTAGTTTTTTACATACC TCAGGTCATGTTTTTGCATTTGGA GAGTCAAGAACATTGGCTATTGCA AATATGGTTCTTGGGCTAAAGGAA ATTCAAATTCGTGGCGAAATGCGC ACTAATGTTGATTATACAATTGATT TATTACATGTGAGCAACTTGGCCT TCAAAGTTAAATTCGTTTTGATAAT ATTCATTTACTTCAAATAAATTACA TTTTTTCTTTGTAATCTTCAAAATA TATAAATTTATAAAGTACACACATC ACATTGGGCGAAGAAAAGTACACT CCATAAAGTTTAGAATTTTTTTAAA AAAATTTTCATTCTTITITCITATITO TTACACTTATTAGTGTGAACTTTCA CATTCTTGATTITTTCITTTCITTATTT CTGCACATGTAGGCTCCAGATTAT AGAGAAAACAAAATACACACGGGT TGGTTAGATAGCCGAATTGCGATG CGGGTTAGAGCAGAAAGGCCTCC TTGGTATCTTTCGGTAGTGGGGGÇ GAGCTCTTTACGTAAGTCATTTCA TATCACAATGTGGTTTCTCTATTAC TTATCATCTTTTGAAGCACTTCCA CTTACCATCGGCTTTTGTCGACCT CAGAAAGCCGCTGCTAGAAGTGC AGCCATGGCCTCTGACTATGTTG GTTATCTTGAAAAGGGGCAAATCC CTCCAAAGGTATCATGCATTCCGA AATTTAGAACTTGGGTTTTGTTITT ATAAAAATTGGTTAAAAGTCGTTAT GTTTGTTTTACTTATTAATGTTTCA TTACTTGCAGCATTTATCACTAGT CAACTCTCAAGTTACTTTGAATATT GAGGGGAGCAGATACACAGTGAG TAACAAGATACACAAGCTACTAGG ATTTTTTITGTGTGTATATTAATTC ATCTTTTCTGATTCTCGTATTTGTT GTTAGATTGATATGGTAAAAAGAG GACCTGGAGGTTATAGATTGAAAA TGAACCAATCTGAGATTGAAGCAG AAATACATACTCTACGTGACGGGG GTTTATTGATGCAGGTATGTAATT CATAATGATTCATTTTCGTTITCTG GGTTTATTTAGAACTGTACAATGT GTATCATATAAAATGCATCTTAACA TTGGGGTGCATCTGTGAATCAAAA TGATAATCACTATAATGTTACATAA ATTGTTACTATTTAAGAAAAATGG GTATAACTGAATATACCAGAAATT ATGTTTTACCGATTGATAATCAGTT TTCTTGCAGTTAGTTACAAACTGA TAGTCGTAGCTGAAATGGGTCAC CCAAACACTTGAAAGTGATTACTG CGACTTGAAGTTGCATTAATTGGA TAATCACTTTCAAAGCGAATTGTT ATATACACCAATAACACAATGATA TCTAACTGGTTGATTTAATGTGGT AGTTGGATGGGAATAGTCATATTA TATATGCTGAAGAAGAAGCCGCT GGTACTCGTCTCCTCATTGATGGA CGGACATGTTTGCTTCAGGTGCC AACAACTTTTTTTGTTAACTTTTGC TGTAGTGGTGGCAACATTTACTCA TCTATTTTTAAATTAGTCAGTTTGA GTCATATTTAAGATCTAAAGTGTC AAACGGGTTAAATAGAAAAAACTG AAGGAAACTGGTCAAATAGGCGG TAAGTGGCCTGTGTGTATTCAACA CACATAACCTTCCAAATTATTTITT GTTGGAAATATATCATTCTTATATC ATATTCGGAGGACTAGTTTACATA AATAATTTTACTTTTTATACAAAAA GTGTTTGTGTTCAATCCAAAATCA ACCCAACCTGTACTGTACAAAATT ACCTGTTTTGACCTGAACCAGATC TGTTACCCAGCCTGATGGGATATC TCAATTTGTCACCTTTACCATATCC TTGCTTGTGTGGATTTTAAGTTTG CATTACTTCTTTTTAGAATGATCAT GATCCTTCCAAGCTGGTGGCCGA AACACCATGCAAACTTCTAAGATA CTTAGTCTCAGATAGTAGCCATGT CGATGCTGACACACCTTATGCTGA GGTGGAGGTAATGAAGATGTGTA TGCCGCTACTTTCGCCGGCTTCET GGAGTTATACAGTTTAAGATGTCT GAAGGTCAAGCAATGCATGTTAG CCCTTTTTCTCTATTTTITATTCCA TTTTCGTCTTCTTCAAATCATACAC CGTGGACCCACGAAACAAAGAAA GTTTATTTATTTGAGCTGTTATGAA TGACTTCATTTGTAGGCTGGTGAG CTAATAGCAAGGCTTGATCTTGAT GACCCATCAGCAGTAAGAAAAGC AGAGCCTTTCCATGGAACTTTTCC TCTTCTTGGGTCTTCAACTGCCAT GTCAGATAAAGTTCATCAAAAGTG TGCTACAACTCTAAGTGCCGCTCG AATGATTCTTGCAGGCTATGATCA CGATATTGATGAAGTAATCTTTTC GCCGTATAAGGATTTTACAGTTTC AAAAAGAAGTTGTTCTTCTGTTAA CAAGTTTAACCTTTTATTGTAGGTT GTCAAAAACCTTCTTCGTTGTCTA GATAATCCCAAGCTACCTTTCCTC CAGTGGCAAGAATGCTTTGCAGTT CTAGCCAATCGACTTCCTAAAGAT TTAAAAAACAAGGCAAATTTACAT CTTATAATTCTTATCTATITTTTCOTITT TCTTTCAAATTGGAACATTGAAAT GTATTTTTCTAATTCTGTTATTTGT ATATTCAGTTGGAAACAAAATTTAA GGAGTACGAAGGAATTTCCACCC AACAAGCTATTGATTTCCCCGCCA AATTATTATGGGGAATTCTTGAAG TTAGTTTGCGATTAATAATITTITIT TATTATACACATACACTTTTTCATA TTTAAAGATGTAATATGGTAATGC TATCTGCACAGACACATCTTGAAT TGTGCTCGGAAAAGGAAAGGGGA GCCCAAGAAAGGCTTGCTGAGCC ATTAATGAGTCTTGTCAAGTCCTA TGAAGGTGGCAGAGAGAGTCATG CACGTGGGATCGTTCATGCTCTTT TTGAAGCATATTTATCTGTTGAAG AGCTATTTAGCGACAACATTCAGG TGCGTTTTTTTCTGCTGTGTTGAT CCATGTTTTTTITTTTGGGATTTCTG ATCGGGCATGTACTACCATAACAG TTCTTTCTATTTTATCTTTTITACACT ACACAGCCCAATTTTTTTCAAGGT TAACACATTCCCACCTTAGCTTTA AAAACCTATTTACCTATGACCGGG TCGGCAAAAGTTATCCCTTTATTT CAAACTTTGAAACTGGTAAAAAGT CAACCAAAGTGTAGTTATTAATTC ATTAAACCCTTTGAATTACTTTTCC AAAACTTGGATTATTATAAAATAAA GTTTCTGGGCAATAGTGTTTCCGG TCAACCAACCTGTTCAAAAAATGA CATGATTTGACTTGTTTCTGGACA TGATATAATGTTTCAGGCTGATGT AATTGAACGTCTTAGACAACAATA CAAGAAGGATCTGTCGAGGGTTG TTGACATCGTGATTTCACATCAGG TATGTTAATTCCACTGTTTTGTATC TTCCATTCTAATTGTTTAAGTTAAC AACCTATTTTATGTCGACACAGGG TGTTAAGACTAAAAACAAACTGAT ACTACGACTGATGGAGCATTTGGT TTACCCTAATCCAGCCGCCTATAG GGAAAATCTGATACGGTTTTCTCA ATTGAACCACACTAGTTATTCTGA GGTCAATATTGTCATTTGACATAC TCATACCAGTTTGAATATTTTTCCG AATCTTTTTTATGCTAATACTAGTT TGTGTTTCTCATTTCTTGTTAATAG TTAGCATTGAAGGCAAGTCAGCTG CTAGAACAGACTAAACTGAGTGAA CTTCGTTCAAGCATAGCTAGAAGT CTTTCTGAGTTAGAGATGTTTACC GAAGAAGGTGAGAATATAGATACC CCTAAGAGGAAGAGTGCCATTGA TGAAAGAATGGAGGATATTGTGAG TGCTCCTTTGGCGGTCGAAGATG CCCTTGTTGGTCTTTTTGATCACA GTGATCACACCCTTCAAAGGCGT GTTGTTGAGACCTATGTTCGAAGG CTATATCAGGTATTTTTGCTTCTCT CATATAAAATAATTAATTTGTATCA CATAACTGGAGTCTGCATTATAAC TGAAGCAAATTTCTTGGAATGTTA TAAAGATGAAATCATAGTTATAGTT TCAATTAAAGGCATTATTGGTAAC ACTTACATTGTATGCATCATTTITTG GTAGTGTGAGCAGAGTAGTGATTT TCATGGCAATTAAAAATTAAAATG CTTTGTTTCATCTCTTACTGAATTA CACTGTTGTTCACAAAACTACTTA AATTGATTTTCATCTGAACTTTITG TGCCAAATACCTTGGTTTTTCTAT CCAGATTTACTTITTGTCTTTITTTAC CCAACAAGGCCAGAGCAATGATC TTGATTTAGGTACACAAGATTCTT GTGTTAAAGGAGTCCTACATTTGA TTAATGATCAACATATTTTTCAAAT ACCACAATTTATATTGTAATACAG GGTGTGTATTTTGACTTCAGACCT TTTTCAGCTATTTTTGTAGTAGGC AGAAAGTTGTTAACTGAATTAATAT AAAAATATATATAAAAAGTGAAGA AATGTGTTTGAGTATTGTAATGTAT ACTCTATGTTTAGCTGGCTGGAAA TGTTCCACTATCTTGTATATGTCTA CTACACTCTTCATGAATTGCTAAA GAAAAGAATTTTGTGATGTAAATA TATATTCAGTTATTTACACTTCTTA CGGGCCAAAGTCACGTGAGGTTT ACTGACCACTCACTTCATATCTGT TATCAGCCATATCTCGTGAAGAGG AGTGTTAAGATGCAGTGGCACAG ATCCGGACTTATTGCTTCATGGCA ATTCATGGAAGGACACGCTGAAG CTGTTAATGTGTCTGATTATGAAA CTATTGATACACAATTGGTAGATA AGAAATGGGGAGCTATGGTTATTA TTAGATCTCTTCAATTTTTACCTGA TGTCATAAGTGCAGCTCTTAAAGA AACTACTTATAAACATCATGGCAC AAGTCAAAATGGGGATGCCAATC CAAGTTATCAAGGTTATATGATGC ATATTGCATTGGTAGGCATCAACA ACCAAATGAGTTTGCTTCAAGACA GGTATACAATGTTTCATGTTGATC TTATGTATCGAATTTGTAAAATACC ATTTGCTACAAAAAGTTGAAATAA AGCAACTTATTGTACCCAAGTTGT TTATGTGTACTGATGCTAGAGTGT CAAAACAGACAGGTTGGATAGCAT GCCTAAACTGATTTGGGTCAAAAC GGGCCAGATTAAATCTGCTCCCAT TTGTATTAAAATCTTTCTATTITTAC AAGTACTTAATGTAATATTGGATG CTTACAACGACTATATTATATCCTT TATTAACTTTTAGCTTAGTACAAAC ATACATATAATATTCCCTGTATTAA CTCTTAGCTAAGTACTTAATGTATT TTGGATGCTTACAACAACTATCAT ATTACCTGTTTGACCTGTTATCAA CTAAGTACAAACATACATATAAAT GGCTGTGATAACTAGGTGACCAA CCTTAAATTACCAAAAAGGTACTT GTTGTATTTTTCATCAAACTAACCA TCTCATGACATTATGTCATTATGAT ATGCCATGGTATAGGGATAAAAAT GGAAAAATGGGCCTAGTATCAGG CCATGATATTTGCCATGTTTACCA AAGGATAAGTTTGATGGATATAAT TTTITITTCCCCGATGATCTGAAAT TAATGGACATGTTATCTTTTTAACT GCAGTGGTGATGAGGATCAGGCT CAAGAGAGAGTCAACAAGTTAGC AAAAATACTCAAAGATAAAGAAAT AAGTGTGAAACTAAAAAATGCAGG ATATGAAGTTGTAAGTTGCATAAT ACAAAGAGACGAAGGTAGAGGCC CGGTGAGACACTCATTTCACTGGT CAGAAAAGAATCGTTATTATATCG AAGAGCCATCATTGCGTCATTTGG AGCCTCCATTATCGATTTATCOTTG AACTGGTTTGTACTCTTAACACGC CTGAATACGTTCTTGATAACGAAA GAACAATAATTCATAAATGTATTAT TTGTTTAGGACAAGCTTAAGGGCT ATGAGAATGTAAAGTACACTCCAT CACGTGACCGTCAATGGCACATG TATACTGTTGATGCTAAACCACTT CCGGTTCAAAGAATGTTTCTTAGA ACGCTTGTAAGGCACCCGACAAA AGAATGGTTCTTGCCCTCAGGATA CCAAGATTCGGAAGTTGTGGACC CACGGTCTCAGTTAACTTTACCTT TTACATCAAGGAGCATCTTGAGAT CTTTAGTGACCGCCATGGAGGAG TTGGAACTTCATGTTCATAATGCT ATAGTCAAGTCGGACCATGCTCAT ATGTACCTCTATATATTGAAAGAA CAACAAATAAATGATCTTGTTCCA TATACTAAGTAAGCATTGCCATCC TCTTTCTGAGACATTATATATGTAT GGATAATATTATAATTTCACAAGTT GTAAACAGGAGAGTGGATGTAGA TTCTGGTAAAGAAGAAGGTGTGGT TGAGACGCTTTTGGTGAAGTTGGT CCGTGAACTTCATTCGATGGTTGG GGTAAAGATGCACCGGTTAGGTG TTTTTGAGTGGGAGGTGAAGCTTT GTATGGTATCATCTGGTGAAGCCA ACGGTGTTTGGAGGGTEGGTEGTE ACAAATGTGACTGGGCATACCTG CAATGTACATGTAAGTCATTAAAC GGACTTTTTAGACATTTGACCATA CTCGATATCTTTTACCTACAATGA ATTTTTGAAATTTGTATATAGGTGT ATCGGGAAGTAGAAGATACTGTTA AACACAAGGCAGTGTATCATGCTC CCTCTACATTGGGACCTTTACATG GTGTGCTGGTGAACACACCCTTTC AGCCTCTGGGATTACTCGATCAGA AGCGTCTTGTCGCCAGGAAAAGC AATACTACTTACTGCTACGACTTT GCACTGGTAAAATCCCCGTTCTTC CCTTTTAAGTCAGATATGCATTTG CTATACTATTTTTTACAAAGTACTG GTTCTTATTGATCATACTTGTATGT GCAGGCATTTGAAGCAGCCCTTG AGAATATCTGGTCATCAAAACTGC CTGGTGTAAGCAGGCCCAAGGGC AAACTTGTAAATGCGATGGAGCTT GTGTTTGCTGACCGAAGAGGTTTA TGGGGCACTCCACTTGTGCCAGT AACGCGCGAGCCTGGACAAAATA ATGTGGGAATGGTAGCGTGGACT ATGGACCTCTGCACACCAGAATTT CCTGATGGTAGGACGATTTTAGTT GTTTCAAATGACGTCACATTTAAA AACGGATCTTTTGGTCCTATCGAG GATGCGTTTTTTGAGGCAGTCACT GAGCTTGCTTGTGCCAAAAAACTG CCGCTCATTTACCTGGCGGCAAA CTCAGGGGCCCGTATEGGGGEGTEG CCGAAGAGGTCAGATCCAGCTTT AGAATTGGGTGGTCTGATGAGTC AACTCCCGACTCCGGCTTTCAGTA TTTGTATCTAACTCCCGAAGATTA CTCTCGTTTGGAATCATCAGTAAT AGCACATGAAATTCGTCTATCCAG TGGTGAAACAAGATGGGTCATTGA TACTATTGTCGGGAAAGAGGATG GATTAGGGGTTGAGAATTTGAGTG GTAGTGGGGCGATTGCTGGGGCT TTTTCGAAGGCATATAAAGAAACT TTTACTTTAACCTACGTGACTGGA AGAACTGTTGGGATAGGTGCATAT CTGGCCCGTCTTGGGATGCGATG CATACAAAGGCTTGATCAACCGAT TATTTTAACTGGGTTTTCTGCACTA AACAAGCTTTTGGGCCGAGAGGT TTATAGTTCGCAGATGCAACTTGG TGGACCTAAAATTATGGCCACGAA TGGCGTTGTTCATCAAACTGTATC TGATGATTTGGAAGGTGTCTCGG CTATCTTGAACTGGTTGAGCTATG TTCCGCCTTACGTTGGCGGTCCÇA CTTCCTGTTTTGCCACCCATGGAT CCACCAGACAGGCCCGTCGAGTA CCTGCCTGAAAACTCATGTGATCC TAGGGCAGCCATTTGTGGGACCG TGGATGGTAACGGGAAATGGGTT GGTGGGATTTTCGACAGAAACAG TTTTGTGGAGACGTTGGAAGGTTG GGCAAGGACAGTTGTAACAGGTC GGGCGAAACTCGGTGGAATCCCT GTGGGGGTTGTTGCTGTCGAGAC ACAAACGATGATGCAAGTTATACC TGCGGATCCTGGGCAGCTCGATT CACATGAACGTGTAGTTCCTCAAG CTGGGCAGGTCTGGTTCCCGGAT TCTGCTAGTAAGACAGCTCAAGC GCTGATGGATTTTAATCGAGAAGA GCTCCCCCTTTTCATTATGGCAAA CTGGCGAGGGTTTTCAGCCGGTC AACGTGACCTTTTTGAAGGGATTC TACAAGCGGGATCGACAATTGTA GAGAATCTTAGAACCTATAAACAG CCAGTTTTTGTCTACATTCCAAAA ACAGGTGAGCTTCGAGGTGGTGC ATGGGTGGTCGTTGACAGTCGAA TCAATTCAGACCATATAGAAATGT ATGCAGAAACAACTGCGAAAGGA AATGTTCTTGAACCCGAAGGTATG ATTGAAATAAAGTTCCGAAATAAA GAGCTGGTAGACTGCATGGGTCG ATTGGACCCACTAATTTGCAATCT AAAAGAAAAACTTAAAGAAACGAA GCTCGATCAAGCAATCACCCAGC AGATAAAAGCCCGTGAGAAACAG CTTTTACCAATTTACACTCAAATCG CTACAAAGTTTGCTGAACTTCATG ACACATCATTCCGAATGGCTGAAA AAGGTGTTGTCAAAAAGGTTGTTG ACTGGGCAATTTCCCGGTTTITCT TCTACAAAAGACTCCAGCGTAGG CTGGCCGAGGCTTCTCTAATCAA GAGTGCTCGTGATGCTGCTGGTG ACACGCTTTCACACAAATCTGCTC ATGAAATGATCAAAAAATGGTTTTT GGACACAAAAAGTGAAGATATGTG GGTGAATGACGACGCCTTTTTCAC ATGGAAAGATGATCCATTGAACTA TACTAGCAAATTAGCCGATCTACG TACACAGAAGATATCAAATCAGTT ATTAAAGATTGGCAGTTCACCTTC CGATCTGCAAGCTTTACCACAGG GACTCGCTGCACTTTTGCAAGAG GTAAACCATAATATCCCGATTACC TGCCGTTTTAAAATTCATAAATTTC ACTGTTTTGTTTAACTTTGTTGTGT TCTTCTATGATGTAGGTGAATCCT GCAGCCAAAAATAAATTGATTGAA GAACTCAGGCGGATAATTGAGTA GGAATCGATAGGTAACTATTATCA AGGAGTTCTTCATTATAAATTITTGC CAGCAGTTTGAGATTTTTCCAGCC AAATGAGAAGCCTTTGAACCTGTG TACATTAAGGTGTTGATAGGGAGA TAGAGTAAAGATAGTATAAATTGT AATTAGTGTTCACAAGAACTTTAC ATTAGAATCATTATATATCATGGTC AATTCTTTTAACAAACATAATTCAA ATTCATATTCTGATATTCATATGTT GAAACAATTGCTTTTCTTTTTGATT TTTITGTTCTCTTTTCCCOTTCGGTT TCTGTTTCTTTACTITTACTTTCTCG TTTGCGTTCTTCTTITTTCCITTITCTC TCAAGTTCTTCTCTTTCCTITGCTT TTTTCTTCTITTCTTTCGAGTTCOTTCE TTTTTTCCTTAACTTATCTTTCOTCG TGTTTTACCTTCTCTITTCTCGTGTT TTACCTTCTCTTTCATTTTCTITITT CATTTTCTTCTTCTCTTTTCGTAGG AGTATCCGCTTGATGATGTTCATA CACATTCTTACTTTGGAATTATTGT CTGCAAATGTCAAATCAATAGAGA ACTATGTAGATATGCTTTAAATGG CATATACTTCTITTITGTTTTTGTCA ATTATTTATTTATAGGTGCATACAT AGTGTTTATCAACATTGTAGGAAA TGACAAAAGTTTGTTTTTCAAACG GGCAAACCAGATTCTCGTTGTAAT CAACTGTAACAATGTAGGATTGTG TTTGTCCGTCGACCAAATGTTGCA AGTTCGATCAATATCTGTACGAAC GTTTCAATCAACACATCGAAGAAT AATTGAATATAATCCAAGTTAATGT TTGAAAAGCAACAAGATAACAATA TAAGATTGGTGGTCCTGTTCAGAA AATGGTATTTATGTTTAACTGTGTA TGAAGTAAAACAAACATATGATTG AGATTTTAATTCTCAACATCAATTT CAACACTAACATAAGTTCATTACT AAGATATAGTTTTCCATTATTAGCT TAGACTTCTGTCATAAAAAACGGA CATCAAGTAAATGTAGAAAAATGT AGCGTCATATGTCTTTACACGGAT TCAAACCATTATACAACTTACAAA CTGTTGACGGTTATATCATGTGCA ATTGTCTAACAGAATCCAAAAGCG TAAAAAAAAGAGGCAAAATTGCAG TTTCCTACATTGTTCTCTTTATCOTC CAAGCCCTAGTCATTTCATGTATA AACAATCTAACAAACAAGCTTATT CTGTAAAAAATCCAACAATTCTGA TTTCATATATAGGTTGAGTACATAT GGGGATTCTAACTAGTGAGTAGT GACTCTAAACTTTAATTCTTCTTGC ACTTCACATTTTACTGATGAGGTC AGACCTCATGAGCAGACTTTGATG AACATGTATGAACAGCATCTGCAA CTGTGAGAAAAATCTTGTTTTCGC CAATCAAGTCAGGGAAATCCGCT GCATATAGCTTGTCTAGGACGAGT TGCCCGGGGTTTGCAAGAACAAG CTGCCATGTCAATTTAGTTTTTAGT CCTTGAGATGGCATTACAACACAT GCAATTTATTATTTATACACACTTA GAACCATTTGTTAATAAATTGGAG ACTGTTTTACTAACCTGAACATCT CTCTTTTGCAAACTTCTGTGTAAC TCTTCAAAGGCATGGATTCCACTG GTGTCAATATCAGTAACAGCTGCA ATTAGGCAACCATACGTTAGAGAG AAAAGTTTCAATGACCCAAAATGT AAAGGTAACCATGGTAAAAGCTAG TTTCTTACGCGACATTTCAACTATT AAGAATTGAATATTTGGTAGGTAT GCTGCTTTTAGATTTTCTTCTTCCOT CAGTTAGCCATCTCAATATCCTGC AAATAAAGTGCTCGATTTATTACTT GAAAATGATCTGCTGGATAATCTA TATAGTTCAAGATTCTTAAAATAAT TCACAGTTTGCAGAAAAAAATGTA CCTTTCTTTGATGTAGTTG-
GAGTTGGAAA 52 Euphor- |cD- /2292 CCGGAAGGAAAATCTTGATAGTAG bia hete- | NA- CGAACGACGTGACCTTCAAAGCC rophylla | Con- GGGTCTTTCGGCCCGAGAGAGGA tig TGCATTCTTTTCCGCCATAACCOGA
TCTTGCATGCACCAAAAAGCTCCC TTTAGTCTACCTGGCAGCAAACTC TGGTGCTCGTATAGGTGTTGCCG AGGAAGTCAAGTCTTGCTTTAAAG TCGGTTGGTCAGATGAGTCATCTC CCGAGCGTGGTTTCCAGTACGTA TATTTGACTCCCGAGGATTATGTA ACCATTGGATCATCGGTGATAGCA CACGAGCTGAATCAGAATGGAGA AACACGGTGGGTCATAGATGCCA TTGTTGGGAAAGAGGATGGCTTA GGTGTCGAAAATTTATCGGGAAGT GGAGCCATTGCTAGTGCATACTCA AGGGCATATAAGGAAACCTTCACA TTGACATACGTAACTGGAAGAACA GTGGGAATCGGTGCTTACCTGGC ACGCCTCGGGATGAGATGCATAC AACGGCTCGATCAACCGATCATCT TGACCGGGTTCTCCGCGTTAAAC AAACTCCTCGGCCGTGAAGTGTAT AGCTCTCACATGCAACTCGGCGG TCCGAAAATTATGGCCACCAATGG GGTAGTCCATCGCACCGTCTCCG ATGACCTCGAAGGTATTTCGGAAA TCCTGAAATGGCTAAGCTGTATTC CCCCTCAMAGCGGCGGGGCAATT CCGGTATTTCCTTCTCOGGATCOCOT CCGGAGCGACCCGTGGAGTACTT CCCAGAAACATCGTGCGACCCGC GGGCGGCCATCTCEGGGTACAATG GACGGCAGCGGGAAGAAGTGGCT CGGGGGTATTTTCGACAAAGACA GCTTCGTGGAGACACTGGAAGGG TGGGCGAGGACCGTGGTÇGACCEG GGCGGGCAAAGCTCGGGGGGAT TCCGGTTGGGATAATAGCCGTCG AGACTCAAACCGTGATGCAAGTG ATCCCCGCCGACOECGGGCCAGCT GGACTCGCACGAGCGGGTCGTGC CCCAGGCGGGTCAAGTATGGTTCE CCAGATTCGGCGAATAAAACCOGC CCAAGCGATTATGGATTTCAACCG AGAAGAGCTCCCGCTCTTTATCCT CGCCAACTGGCGAGGCTTCTCGG GCGGCCAACGAGACCTCTTCGAA GGTATCCTTCAGGCGGGGTCÇAC CATAGTGGAAAACTTAAGGACATA TAACCAACCGGTTTTCGTATACAT CCCTATGATGGGCGAGCTTCOGTG GTGGGGCCTGGGTTGTTGTGGAC AGTCAGATAAATTCTGACCACATC GAGATGTACGCTGATCGGACGGC TAAAGGCAACGTCCTTGAACCGG AAGGAATAATCGAGATCAAGTTTA GAACAAAGGAGTTGCTCGATTGC ATGAATCGACTCGACCCAAAGCT GATATCTTTTAAAACCAAACTAAC CGAAGCGAAGAATAGTGGGACCT ACGGGATGGTCGATTCCGTACAA CAGCAGATAAAATCCCGGGAAAA GCAACTTCTGCCGCTATACACACA AATCGCCACACGATTCGCCGAGC TTCACGACTCGGCTTTACGAATGG CGGCAAAGGGGGTGATTCGAGAA GTTGTCGACTGGGGGATTTCACG ATCTTACTTCTACAAAAGGTTAAG AAGGAGAATCGCCGAGGCTTCGT TGGTGAACACCGTGAAAGATGCA GCGGGTGATAAGCTCCAGCATAA GTCGGCTATGGAGTTGGTCAAAA ACTGGTTTCTGGACTCGAAAGGC GATTGGGAAAACGATGAAGCTTTC TATGCTTGGAAGGATAATCCCGC GAATTACGAGGAAAAGCTACAGG AGTTACGGGTCCAGAAGGTGTTG CTTCAGTTAACTAACATTGGCGAG TCTTTGTCGGATTTGAAAGCTTTA CCTCAAGGTCTTGCTGCCCTTCTA AATAAGGTGGAGCCATCGAGCCG AGGGGCGTTGATCGATGAGCTTC GGAAGGTGCTTAATTGATTTTCGG TAAGTGTTTCTCGGCTACTAAATA TGTTTTACTTTGGCTTCAGTCTCT GGGTAGTTTGAATCAATAGAAAAT GCCAATGTGAAAATACCCAGTAAT ATATTTGATAAGTGTAAATGTAACT ATTATTATATTTAAGTGAATAGGG GGAATTAGTTCATATGATTATTGTT GTTATAAACAAATCAGAGATAGAG AGAGCTATATTTATTATTATATTTG CGAATTAAAGTTATTAGGAGTAGT ATAATTTGGCGGTTGTTGCATTTT ACGTGTAATGATCTGA-
ATGTTGTTTGTTCGTGATTATTG 53 Euphor- |cD- 11338 |TTGACGGGAGGACTTGCTTGCTA bia hete- | NA- CAGAATGATCATGATCCGTCAAAG rophylla | Con- TTAGTGGCAGAGACGCCATGCAA tig ACTTCTGAGATATTTGGTTTCAGA
TGGTAGTCATATTGAAGCTGATGC TCCATATGCAGAGGTTGAAGTTAT GAAGATGTGCATGCCTCTTCTTTC ACCTGCTTCTGGAGTTGTCCATTT TAAAATGTCTGAAGGTCAAGCAAT GCAGGCTGGGGAGCTCATTGCAA GGCTTGATCTTGATGATCCTTCTG CTGTAAGAAGGCAGAACCTTTTCA TGGGAGATTCCCGCTACTTGGCT CTCCTACTGCTATTTCTGGTAAAG TTCATCAGAGATGTGCTGCAAGTC TAAATGCAGCCCGTATGATTCTCG CTGGCTACGATCATAATATTGATG AAGTAGTGCAAAACTTGCTCAATT GCCTTGATAGTCCTGAACTCCCTT TCCTTCAGTGGCAAGAGTGCTTGT CTGTTCTAGCAACTCGCCTTCCCA AGGATCTTAGGAGCGAGTTGGAA TCAAAATACACAGAGTTTGAAGGA ATTTCGAGCTCCCAGAACATTGAC TTCCCTGCCAAACTGTTAAGGGGT GTCCTCGAGGCACACCTGAAATC CTGTCCTGAGAAAGAAAAAGGAG CGTTGGAAAGGCTTGTTGAACCTT TGATGAGTCTTGTAAAGTCTTATG AGGGAGGACGTGAGAGTCATGCT CGAGTGATCGTCCAATCACTITTTT GAAGAGTATTTATCTGTAGAAGAA TTATTTAGTGACAACATCCAGGCT GATGTGATTGAACGTCTCAGACTT CAATATAAGAAAGACCTTTTGAAG ATAGTGGACATTGTCCTTTCTCAT CAGGGTGTTAAGAGTAAAAATAAG CTGATACTACGGCTCATGGAACAA CTTGTTTACCCCAACCCTGCTGCA TATAGGGATAAACTCATTCGGTTC TCTCAGCTTAACCACACCAGCTAT TCCGAGTTGGCATTGAAGGCAAG TCAACTCCTAGAACAAACCAAACT GAGTGAACTCCGTTCCACTATTGC TAGAAGCCTTTCGGAATTGGAGAT GTTTACCGAGGATGGTGAAAATAT GGATACTCCCAAAAGGAAAAGTG CCATTAATGAACGTATGGAGGATC TTGTGAGTGCTCCTTTGGCTGTTG AAGATGCTTTAGTGGGTCTTTTCG AGCACAGTGATCACACCCTTCAAA GGCGAGTGGTGGAAACTTATGTT CGTAGGCTATATCAGCCCTATCTG GTCAAAGGTAGTGTCAGGATGCA GTGGCATAGATTTGGTCTTATTGC TACATGGGAATTCTTGGGAGAG-
CATATCGG 54 Euphor- |cD- |1250 TAATATGATGCACATAGCATTGGT bia hete- | NA- AGGCATCAATAATCAGATGAGCTT rophylla | Con- ACTACAGGATAGTGGTGATGAGG tig ATCAGGCACAAGAGAGAATTAACA
AGTTAGCCAAGATTCTCAAAGAAC AGGAACTAGGTTCCAGTTTGAGCT TGTCAGGCGTTGGAGTTATTAGCT GTATCATACAGAGGGATGAAGGG AGAGCCCCTATGAGGCACTCCTTT CACTGGTCAGAGGAAAAGCTTTAT ATGAGGAAGAACCTCTATTGCGAC ATTTGGAACCTCCACTATCCATCT ACCTTGAACTGGACAAACTTAAAG GCTATGACAATAGACAATATACTC AGTCAAGGGACAGACAATGGCAC ATGTACACTGTTGTAGACAAACCA GTTCCAATCCAGAGGATGTTTCTA AGAACCCTTGTGAGACAGCCCAC AAGTACTTCATATCAAGGTCTTGG CGCCGAAGCACCCAATGTGCAGT GGGCCATGTCCTTTACGTCAAAGA GCATTTTGAGGTCCTTAGTAGCTG CAATGGAGGAACTGGAGCTTCAC GTGCACACTGTCAAATCTGACCAT GCTCATATGTACCTCTGCATATTG AGGGAGCAACGGATAGAAGATCT TGTTCCATACACGAAGAAAACCGA TGTAGATGCCAACCAAGAAGAAG CTGCGGTAGCAAGAATCTTGGAA GAACTAGCGAGGAAGATACATGC GTCGGTTGGAGTCAGAATGCATA GGTTAAATGTTTGCGAGTGGGAA GTGAAGCTATGGATGACATCATCT GGACAGGCAAATGGTGCTTGGAG AGTTGTCACAACAAATGTGACTGG GCATACCTGTGCTGTGCATATATA TCGGGAACTTGGGGACGACAGCA AACACGAAGTGGTTTACCATTCGA TCTCTCCAAGAGGCCCACTGCATA GCATGCCAGTGAATGCTGTTTATC AGCCCTTGGGAGTTCTCGATCGA AAACGTTTGTTGGCAAGGAAGAG CAACACCACTTACTGCTATGATTT TCCACTGGCGTTTGAGACAGCCA TCGAACAATTATGGGAATCTCAAT CACCAGGGACTGAAAGAAGCAAA GAAAACGTCCTAAAAGTCTCGGA GCTTGTTTTTGCCGATCAGAAAGG TACCTGGGGAACTCCACTTGTTCA TGCAGAACGGCCAGCTGGGCTTA ATGACGTGGGCATGGTAGCATGG TGCATGGAAATGTTCACCCCGGA
ATGCCCTTCCGGAAGGAAATCTTG 55 Euphor- |cD- /959 TCGCTCATAATCGCTTGATCGCAG bia hete- | NA- TCCTATTCGAGTTCAATTITTITTGA rophylla | Con- GATTCCGCTTATATTTTCAGAATG tig TTGGAGACACAGAGGAGGCAGCC
GTTAGCAGTAGGGGTTACTCGTG GGAATGATTTCACCAATGGTGTGC TTACGATGAGAAGCCCTGCTACAA TATCAGAAGTAGATCAATTTTGCC GTGCTCTTGGAGGAAAGAGACCG ATCCACAGTATATTAATTGCAAAC AATGGAATGGCAGCTGTCAAGTTT ATACGAAGTGTTAGGACATGGGC TTATGAAACTTTTGGCACTGAAAA GGCTATCTTGTTGGTGGCCATGG CAACTCCAGAAGACATGAGGATC AATGCAGAGCATATTAGAATAGCT GATCAGTTTGTGGAAGTTCCTGG GGGGACAAACAATAACAATTATGC CAATGTGCAACTCATTGTTGAGAT GGCAGAGGTCACCCATGTTGATG CAGTTTGGCCTGGTTGGGGACAT GCATCTGAAAACCCAGAGCTTCCA GATGCACTAACTGCAAAGGGAAT CGTATTTCTTGGGCCCCCAGCTG CGTCCATGGGAGCTTTGGGTGAT AAAATTGGATCCTCTTTGATTGCG CAAGCAGCAGATGTTCCTACTCTT CCATGGAGTGGCTCTCATGTGAA AATTCCTCCAGAAAGTTGTTTGAT TACCATCCCCGATGACATATATAG AGAAGCATGTGTTCACACAACAGA GGAAGCTATTGCAAGCTGCCAAG TTGTTGGTTACCCTGCTATGATAA AGGCATCATGGGGCGGTGGTEGT AAAGGCATAAGAAAGGTTCATAAT GATGATGAAGTTAGGGCATTGTTT AAACAAGTTCAGGGTGAAGTTCCA GGATCACCCATATTTATAATGAAG GTTGCTTCCCAGAGTCGACATTTA GAAGTCCAATTGCTCTGCGATCA-
ATATGGAAATGTAG 56 Euphor- |cD- /1935 CCAATTACCGTTGCACCATTGGTG bia hete- | NA- ACTGTAAAAAAACTAGAGCAGGCA rophylla | Con- GCTCGAAGGTTAGCGAAATCTGT tig GAATTATGTGGGCGCTGCTACTGT
TGAGTATTTGTACAGTATGGAAAC TGGCGAGTACTATTTTCTAGAGCT CAACCCTCGGTTACAGGTGGAGC ATCCTGTCACAGAGTGGATTGCTG AAATAAATTTGCCTGCTGCCCAAG TAGCTGTTGGGATGGGAATTCCTC TGTGGCAAATTCCTGAGATTAGGC GATTTTATGGAATGGAACATGGTG GAGGATATGATGCTTGGAGGAAA ACTTCAGTGGCTGCTACGCCTTTT GATTTTGACAAGGTAGACTCTACA AAGCCAAAAGGTCATTGTGTAGCT GTACGTGTGACAAGTGAGGATCC AGATGACGGTTTCAAGCCTACTAG TGGAAAAGTACTGGAGCTGAGTTT TAAAAGCAAGCCAAATGTGTGGG CTTATTTCTCTGTGAAGTCTGGTG GAGGCATTCATGAATTCTCAGATT CACAATTTGGACATGTTTTTGCAT TTGGGGAGTCCAGAGCTTTGGCA ATAGCTAATATGGTTCTTGGGCTG AAGGAAATACAGATAAGAGGAGA AATCCGCACCAATGTTGACTACTC TGTTGACCTTTTACATGCTTCAGA TTATAGGGAAAATAAAATTCACAC AGGTTGGTTGGACAGTAGAATAG CTATGAGGGTTAGAGCAGAAAGA CCTCCTTGGTACCTCTCTGTTGTT GGAGGGGCACTATATAAAGCATC TGCTAGCAGCGCAGCTATGGTTT CTGATTATGTTGGTTACCTTGAAA AGGGCCAAATCCCTCCCAAGCAC ATATCACTTGTGAACTCTCAAGTT TCATTGAACATCGAAGGAAGCAAA TATACGATTGACATGGTTA-
GAGGGGGGCCAGGGAG 57 Euphor- |gD- |12503 | TTITTCAGGTTTGTTTGTTTCGATTT bia hete- | NA- TCCGATTGTGTTTTTTGAGTCGCT rophylla | Con- GTTGCTTGATTTCTGCTGCTGTTA tig CTGCTGGTTGACTCTTCTAGTGTG
TTGATTGAGATTTGTTAGTTTGATT CGACTTCGATTTTGGAATCGGATT TTTGAACTTGGAGTTGTAAGTGTT TTGAAGCGTGTTTTTCGGCGTTTT AGTTGCGTTTTTCTTATGGATCCG ATTCTTTTATATGAATGCGGCGTT TGGCGCTGAGCAACATGAATTGG AATAAACTTGTGGTATTTTGCTCTT TTTCTATATATTAGTCTAATTCAAC TTCGATTATGGAATCTGATTTTTGA ATTTGGAGTATATGTAGTATATTTA AACATGTTTTTCGGTGTTATCATT GTGTATTTTTTATGGATCCTGTGC ATCGGAGATGCGTTTATATGAATA CTGTGTTTGGTGCTGAGCAACATA AATTGGATTATACTTGTCGAAAAT AATTCTCGTAATAAGGTTCAAGGT ATCTAGAAGTCTACCTGAAGTGAT ATAGTGGACCATGCGGATTTGATT CTTTGAGTTGTTTTTCTTCAAGTCA AAGATCCTGTTATATTTAATTATTT CTTTTGATTTATGAAATGAGTAATT AAGCAAGTGGTATGCTCAATTCGT TGAAAATATTATGTATTGAAAAGG ATTTGAAGGTTACGAACTGGATTT TCAACTCGAATGAGTTTTITIITTGT GCAGAATGTTGGAGACACAGAGG AGGCAGCCGTTAGCAGTAGGGGT TACTCGTGGGAATGATTTCACCAA TGGTGTGCTTACGATGAGAAGCC CTGCTACAATATCAGAAGTAGATC AATTTTGCCGTGCTCTTGGAGGAA AGAGACCGATCCACAGTATATTAA TTGCAAACAATGGAATGGCAGCT GTCAAGTTTATACGAAGTGTTAGG ACATGGGCTTATGAAACTTTTGGC ACTGAAAAGGCTATCTTGTTGGTG GCCATGGCAACTCCAGAAGACAT GAGGATCAATGCAGAGCATATTAG AATAGCTGATCAGTTTGTGGAAGT TCCTGGGGGGACAAACAATAACA ATTATGCCAATGTGCAACTCATTG TTGAGGTGTGTAAGTTCATAACCT TTTAGCATATTGGATAGCTTATGTT GTGTTAGTCTAAAGTTCGATAATT CTAAGCATATAATGATATTAAATGT GTTTAAGGATTTCTCAGTAATAGG AATTTGTAAATCTTTTCTGTCAATG GGTTTTACAGAAATTCATAAATTAT AATGTAATCTAGAAGCTTTGAAAT TGTATTTTTGCACATCTCAGAAGA TTATGAAGTAATAGGCTGGTATAC AGTGAATTTCATTATTGCAAGATAT TGTTGTTATGTGCTCACTCAAGAG CATTCTTTTCAATTTGGCAATGTG AAAAGGTTCAGTTAGAAATATCAC TTGTTACCCTTGTTGTTTGCATAA CTAAGTTTGATTTTGTGTCCAGAT GGCAGAGGTCACCCATGTTGATG CAGTTTGGCCTGGTTGGGGACAT GCATCTGAAAACCCAGAGCTTCCA GATGCACTAACTGCAAAGGGAAT CGTATTTCTTGGGCCCCCAGCTG CGTCCATGGGAGCTTTGGGTGAT AAAATTGGATCCTCTTTGATTGCG CAAGCAGCAGATGTTCCTACTCTT CCATGGAGTGGCTCTCATGTAAGT AATGCTCTTCTCAAGCTGTTCOTITT CATTTTCTGTAGTCATTCCAATCTA AGATATCATGATCTTCCTTATAGG TGAAAATTCCTCCAGAAAGTTGTT TGATTACCATCCCCGATGACATAT ATAGAGAAGCATGTGTTCACACAA CAGAGGAAGCTATTGCAAGCTGC CAAGTTGTTGGTTACCCTGCTATG ATAAAGGCATCATGGGGCGGTGGÇ TGGTAAAGGCATAAGAAAGGTTTG GCTTCGATATAACAAATTTCCGAG TGTAGTGTTCAAGTCTGTAGTGTA CGATGGCTGAGTTTTGTTTTCITTG GATTATCTAGGTTCATAATGATGA TGAAGTTAGGGCATTGTTTAAACA AGTTCAGGGTGAAGTTCCAGGAT CACCCATATTTATAATGAAGGTTG CTTCCCAGGTTAGGATATTATCTA GCTTCTAATTTGATACAAGAGATT TTACTTTGTGATTCTTGACGCGTG AATCGAATTCTGATGATCTATTTG ATTTTCCTTATGTAGAGTCGACAT TTAGAAGTCCAATTGCTCTGCGAT CAATATGGAAATGTAGCAGCTTTG CATAGCCGTGATTGTAGTGTTCAA AGGCGGCATCAAAAGGCATGTTT ATTTCTCTCAAGTAATTTTGATTTT GTCTGCTTAGTGAAATTGACCATG AAAGTATAAGCTTAGTGTGAAGAG CCTGAGGCTCTGACCACATGCAT GTTGAGAATGAGCCAGTGACTTTT AATCAGTGGCTCAACCATTAATTT CTCCCCTTCCAAATTTCAACTGTT TGTACATCTATCTAGTATCTACTAC ATGGGTTATGCATTTCAAAAAAGG CCTAACTTGTGTTGAGATGTGAAA CAGATAATTGAGGAGGGTCCAATT ACCGTTGCACCATTGGTGACTGTA AAAAAACTAGAGCAGGCAGCTCG AAGGTTAGCGAAATCTGTGAATTA TGTGGGCGCTGCTACTGTTGAGT ATTTGTACAGTATGGAAACTGGCG AGTACTATTTTCTAGAGCTCAACC CTCGGTTACAGGTATAAATGAATA TAGTTTGTAGGGATGTGAAGTTGT TATGCTCTATAGTAGTAATGATAT CTAAAATGCTTAAATTTTATGTTGC TCAATTGATGACAATTGGATAAAC CGTATTCACTTGGGAAAAACCATC CTGAATATAGTTCGTACCTCATTC ACCTTGCGTACTACTGATATTGAT CCTATGAATCTGTTTTTTAAAATAT CTTTGTTTCTGTAATAAATTGTTCT TTGACTTTTCTAATGATCTTTAATC TACATCCTAATCTGGATGTAGGTG GAGCATCCTGTCACAGAGTGGAT TGCTGAAATAAATTTGCCTGCTGC CCAAGTAGCTGTTGGGATGGGAA TTCCTCTGTGGCAAATTCCTGGTA TGACCGCAAAAGTTGGAAATTCGC ATTCTCTTGCTCATTAGACATGTTT CTTTGACATTCTGTTCATTTITATT CAGAGATTAGGCGATTTTATGGAA TGGAACATGGTGGAGGATATGAT GCTTGGAGGAAAACTTCAGTGGC TGCTACGCCTTTTGATTTTGACAA GGTAGACTCTACAAAGCCAAAAG GTCATTGTGTAGCTGTACGTGTGA CAAGTGAGGATCCAGATGACGGT TTCAAGCCTACTAGTGGAAAAGTA CTGGTAAGGTTTTCAGGTTGACTA TTCTAATTTGAATTTCCTTCTATTC CAAAATTCCTTATCCTGTAATGAA CTTGTACTTTTATTGTCTTGCACA GGAGCTGAGTTTTAAAAGCAAGC CAAATGTGTGGGCTTATTTCTCTG TGAAGGTGACTTTTTGCTGCTCTC TTTCTTTGGAACATGTTTATGTTGA CACAATTGGTTTCTGACTTAATAA CTTCATTCTGATTTGTAGTCTGGT GGAGGCATTCATGAATTCTCAGAT TCACAATTTGGTAAGTAATAATTG CTAAATAATCACACTTCATGGATA ATAATGAAAAGAAGTTTGTGAGAT GAGTTATCCAATCTGCTGCAAATT AATGGTTCTTTTITATCTTCTTGTG ACATTTTTTTTAACAAAAGCTACAG TCTGCTTTTCAGTTTAGTCTTTTCC GTTTGTTACATTTGCTATCGAAAG CACTCATGATTGTCGTAATCTTTC CTTAGGACATGTTTTTGCATTTGG GGAGTCCAGAGCTTTGGCAATAG CTAATATGGTTCTTGGGCTGAAGG AAATACAGATAAGAGGAGAAATCC GCACCAATGTTGACTACTCTGTTG ACCTTTTACATGTAAACTATCTTAG CTGTTGATGTTCCCTTTATACATC ATGTAAACTTTCACGAGGAACATG AACACGAGTTGACATGCTATGCAG GCTTCAGATTATAGGGAAAATAAA ATTCACACAGGTTGGTTGGACAGT AGAATAGCTATGAGGGTTAGAGC AGAAAGACCTCCTTGGTACCTCTC TGTTGTTGGAGGGGCACTATATGT AAGTTGTCACGATTTCACATGAGA GGATGACTGTATACTTTTGGAATG CTTTATTATGTCTTTCAGAACTTGC CACTTAAGTGTTCAATTITTTITGITT GCACCAGAAAGCATCTGCTAGCA GCGCAGCTATGGTTTCTGATTATG TTGGTTACCTTGAAAAGGGCCAAA TCCCTCCCAAGGTACATCAAAAGT ATATTTGTACAATTGTATATGTTTC TTATTCAGCCGATTATGTTGATGT TGATGTTGATGTTAGTTGATCTTG TTTTCAGCACATATCACTTGTGAA CTCTCAAGTTTCATTGAACATCGA AGGAAGCAAATATACGGTATGGTA CCTTTCATATTAGTATCTTAAATGA ATAAATTTTAGTTTGGTGATGGAT GCCATTTACGTTTGTAAAATCATT GCTAGATTGACATGGTTAGAGGG GGGCCAGGGAGCTATAGATTGAG GATGAATGGATCGGAGATAGAGG CAGAAATTCATACACTGCGTGATG GAGGTTTATTGATGCAGGCAAGTT GACTCATTAACCATGGCTGTTGTA AACTAATAATTTTCGTCCTTTITAT CATTTAATATTTGCTTTAGTCGACC CTCCATGCTTTGGAGACCATAACA GACTCTATTCTGTTTCTTCACAGTT AGACGGAAACAGTCATGTAATATA TGCTGAAGAAGAAGCAGCCGGAA CTCGCCTTCTAATTGACGGGAGG ACTTGCTTGCTACAGAATGATCAT GATCCGTCAAAGTTAGTGGCAGA GACACCATGCAAACTTCTGAGATA TTTGGTTTCAGATGGTAGTCATAT TGAAGCTGATGCTCCATATGCAGA GGTTGAAGTTATGAAGATGTGCAT GCCTCTTCTTTCACCTGCTTCTGG AGTTGTCCATTTTAAAATGTCTGA AGGTCAAGCAATGCAGGTGTGTTT GATTTCACAAACACGTGCTTTTGG GCTTGATAAGTACTTTTTAGTTTTA TATGAATAGTCAGTTTTGATGTGA ATCTAAGAAGTTTTCATGTAGGCT GGGGAGCTCATTGCAAGGCTTGA TCTTGATGATCCTTCTGCTGTAAG AAAGGCAGAGCCTTTTCATGGGA GATTCCCGCTACTTGGCTCTCCGA CTGCTATTTCTGGTAAAGTTCATC AGAGATGTGCTGCAAGTTTGAATG CAGCCCGTATGATTCTTGCTGGCT ATGATCATAATATTGATGAAGTAA GTTGCAAGCTGGCTAGTTTCAACA TGAACTTAATTGATGAATTAATTGT TCATTCTATATTTTGTTGATTGTGT AATTTCATAACAAAATAATGAACTA TGCATTTGGTTTATTATACTGACAA TTATTTGTTGAAATCTGATGTAATA TCTCAATGACATCTATAGGTAGTG CAAAACTTGCTCAATTGCCTTGAC AGTCCTGAACTCCCTTTCCTTCAG TGGCAAGAGTGCTTGTCTGTTCTA GCAACTCGCCTTCCCAAGGATCTT AGAAGCGAGGTGAATAATTTITCT GTAATTTTTTCATGACCACATAGT CTTCTTGCTCACAATTTGATATTG GCAATTTGTATAGTTGGAATCAAA ATACACAGAGTTTGAAGGAATTTC AAGCTCCCAGAACATTGACTTCCC TGCCAAACTGTTAAGGGGTGTCCT CGAGGTGGGTTCCTTATTGCATG GCTCTCTTGGAATTTCTCATTATOT GTTTTTTTTGCTGTTTAATGAGATG TGTATGCTTTTCCTCCAGGCACAC CTGAAATCCTGTCCTGAGAAAGAA AAAGGAGCCCTGGAAAGGCTTGT TGAACCTTTGATGAGTCTTGTAAA GTCTTATGAGGGAGGACGTGAGA GTCATGCTCGAGTGATCGTCCAAT CACTTTTTGAAGAGTATTTATCTGT AGAAGAATTATTTAGTGACAACAT CCAGGTTAGCTTCTTCCTATCAAA CATAATATGGAATTATTTTGGATTC TGAAAGTCTTCCCTCTTTGGCATC TTTTAGAAAATTAAGCATAATACTA GGTACTATATCCATTATTCTTTATA ATCATGAAATTTAATTTTTACAGAA GAAAAGTGGAATTTCTATATATATT TAAACCAAGCTGGCAAGCTTTGAA TTCAATCCTGTTGTTTATTGTTTTA TCCAACATGCCAAAAATATTAGGA ACTTCATGTGACTACTTGTATCATT CTTATTCTGTAATTACAGTAAAGTA ACTTGTCATATCCTAATGTTATAAC TCGTAACATTCTTCTTTAGGCTGA TGTGATTGAACGTCTCAGACTTCA ATATAAGAAAGACCTTTTGAAGAT AGTGGACATTGTCCTTTCTCATCA GGTATCTGATTTTCGGTTTTAATTT TTATCTCGGGTTTTCTAAAATAGA ATTCTGAGTTTGTGGAAATAACTA CCGTATTTGTTGGTTTATAGGGTG TTAAGAGTAAAAATAAGCTGATAC TACGGCTCATGGAACAACTTGTTT ACCCCAACCCTGCTGCATATAGG GATAAACTCATTCGGTTCTCTCAG CTTAACCACACCAGCTATTCCGAG GTTGGCAGCTATACTTGGTCCATC TGTAATTTCATAAAGTTGTTGCTCT GTTTCCTTTTGTTCACAAGTTCATT TTTGAGAGTTTTCCATAGGATGGT GACTGACAGGAAGAGGATTCTAAT GTTTTCTCTTGGAGGATTTITTCOT GTATTTTCATTTCTTGTCGGTCATT GATTAATTCCGTTTCTGGTATCAG TATCATCAAAATGTTGTCTTITTTCOT GTATACTGATGCTGAATTATGTGA ACAGTTGGCATTGAAGGCAAGTC AACTCCTAGAACAAACCAAACTGA GTGAACTCCGTTCCACTATTGCTA GAAGCCTTTCGGAATTGGAGATGT TTACCGAGGATGGTGAAAATATGG ATACTCCCAAAAGGAAAAGTGCCA TTAATGAACGTATGGAGGATCTTG TGAGTGCTCCTTTGGCTGTTGAAG ATGCTTTAGTGGGTCTTTTCGAGC ACAGTGATCACACCCTTCAAAGGC GAGTGGTGGAAACTTATGTTCGTA GGCTATATCAGGTACTGTGTTGTA GAAACTTAAAACTTTTATCTGGTG ATCAAACACTAGACGAAACTTGAT CTTGATCAACTGTTTGTCTACCGC ACCAGCCCTATCTGGTCAAAGGTA GTGTCAGGATGCAGTGGCATAGA TTTGGTCTTATTGCTACATGGGAA TTCTTGGGAGAGCATATCGGGAG AAAGAATGGATCTGAAGGTCAAAT GTCAGATGAACCAGAGGCTAAAA AACAGTCTAATAAGAGATGGGGA GCAATGGTTATCATCAGATCTCTG CAGTTTTTGCCTTCAGTTATTGGT GCTGCATTAAGGGAAACAAATCAA AGCCTTAATGAGTCCATTCCAAGT GGATTAGTAAAATCAGCGAGCTTT GGTAATATGATGCACATAGCATTG GTAGGCATCAATAATCAGATGAGC TTACTACAGGATAGGTAACTTCCT TCGGTACTATAATATAAGCGTTTA TTTTAATCATAAAAATTAGTAGCAT TTTACATTCTATTATTCATTGTAAG ATCTCAAGTCTTCTTAATCATTTCOT GCATTTGAAACCTTGATAGATCTG GATAGATTCCTTATTTTTGTTTAAA ATTTATGATAGAGTTACCTGGTCT CGAACCCTTAAAACATGCACATAT ATTGGCTTGCCAAACATAAGTTAT TTTGCGTTGTCAATTTCGATTATTG ACGGTCAGCTTGTTAATGCTCCTA ACTGGCACCATCTATGACATTTTG CAGTGGTGATGAGGATCAGGCAC AAGAGAGAATTAACAAGTTAGCCA AAATTCTCAAAGAACAGGAACTAG GTTCCAGTTTGAGCTTGTCAGGC GTTGGAGTTATTAGCTGTATCATA CAGAGGGATGAAGGGAGAGCCCC TATGAGGCACTCCTTTCACTGGTC AGAGGAAAAGCTTTATTATGAGGA AGAACCTCTATTGCGACATTTGGA ACCTCCACTATCCATCTACCTTGA ACTGGTTTGTCACCTATCGCAGTG TTTCAATACATTTTTTTGGCAGAAA CCTTTATTGAGCCCCTGAACTTAC CAGTTTTATTCTCAAGTTATTATTT GACTACATTAAATACTTAATTACTA TTGATTCCACATTATGACCTTGCA ATATAATTACAAGTGTTACGTTTTA TTGATAAAATTATAACTGTTGCTAT TTTGTTTTACATATATCAAGGACTG CACTATAGTAAAAAAATGAGGACT CGATAGGATTGGAAAGTTCAGGG GCTTACTAATTGTTTGAGCGGAAA AAAATATATATAAATGTGAAATTGG ATAATTCTATATCATTCATCTGAAG CTTATTATGGCCTTTTTTTGATCCA GGACAAACTTAAAGGCTATGACAA TAGACAATATACTCAGTCAAGGGA CAGACAATGGCACATGTACACTGT TGTAGACAAACCAGTTCCAATCCA GAGGATGTTTCTAAGAACCCTTGT GAGACAGCCCACAAGTACTTCATA TCAAGGTCTTGGCGCCGAAGCAC CCAATGTGCAGTGGGCCATGTCC TTTACGTCAAAGAGCATTTTGAGG TCCTTAGTAGCTGCAATGGAGGAA CTGGAGCTTCACGTGCACACTGT CAAATCTGACCATGCTCATATGTA CCTCTGCATATTGAGGGAGCAAC GGATAGAAGATCTTGTTCCATACA CGAAGTAATTATATCAATCTTITTATG ATTTATTGTGTACTTGGCACCATA ACTTTATGTGTACTCACTATGAGA CTCCATCTCCAGGAAAACCGATGT AGATGCCAACCAAGAAGAAGCTG CGGTAGCAAGAATCTTGGAAGAA CTAGCGAGGAAGATACATGCGTC GGTTGGAGTCAGAATGCATAGGT TAAATGTTTGCGAGTGGGAAGTGA AGCTATGGATGACATCATCTGGAC AGGCAAATGGTGCTTGGAGAGTT GTCACAACAAATGTGACTGGGCAT ACCTGTGCTGTGCATGTAAGTATC TGCGCATCTTATTTCAAGAAAATG TCTTTCCCTTCCATGCATTCCOTTAT TAGTCGACTTAGTAATGGGGAATG TCGAGAAGTGTTGGATGGTTACCA ATGTGAGTACCATCACTGTTTAGA TTAAAATTGACCATTGCTTTAGCA ATACAATAATGAATCTAATTGTGG CATGGGAGGCTTTTCTATGTGTGA TCCATGGAAAAACTTGTATATAGT TCCTTAGTAGGTTTGAGTTGTTIT CATTTTTCTTTTATCACATTGTAAT TGTATTGGTGATTGATACGAAAAT TAGATATATCGGGAACTTGGGGA CGAGAGCAAACATGAAGTGGTGT ACCATTCAATCTCTCCAAGAGGCC CACTGCATAGCATGCCAGTGAAT GCTGTTTATCAGCCCTTGGGAGTT CTCGATCGAAAACGTTTGTTGGCA AGGAAGAGCAACACCACTTACTG CTATGATTTTCCACTGGTTAGTATT TCTATAATCATTAATCAAACATCAG TTTTTTTATTGGGGATAATTAAAAT CAAATAATTTTTCCTGGCCTCATC CTTTTCAGGCGTTCGAGACAGCC ATCGAACAATTATGGGAATCTCAA TCACCAGGGACTGAAAGAAACAA AGAAAAAGTCCTAAAAGTCTCGGA GCTTGTTTTTGCCGATCAGAAAGG TACCTGGGGAACTCCACTTGTTCA TGCAGAACGGCCAGCTGGGCTTA ACGACGTGGGCATGGTAGCATGG TGCATGGAAATGTTCACCCCGGA ATGCCCTTCCGGAAGGAAAATCTT GATAGTAGCGAACGACGTGACCT TCAAAGCCGGGTCTTTCGGCCCG AGAGAGGATGCATTCTTTTCCGCC ATAACCGATCTTGCATGCACCAAA AAGCTCCCTTTAGTCTACCTGGCA GCAAACTCTGGTGCTCGTATAGGT GTTGCCGAGGAAGTCAAGTCTTG CTTTAAAGTCGGTTGGTCAGATGA GTCATCTCCCGAGCGTGGTTTCEC AGTACGTATATTTGACTCCCGAGG ATTATGTAACCATTGGATCATCGG TGATAGCACACGAGCTGAATCAG AATGGAGAAACACGGTGGGTCAT AGATGCCATTGTTGGGAAAGAGG ATGGCTTAGGTGTCGAAAATTTAT CGGGAAGTGGAGCCATTGCTAGT GCATACTCAAGGGCATATAAGGAA ACCTTCACATTGACATACGTAACT GGAAGAACAGTGGGAATCGGTGC TTACCTGGCACGCCTCGGGATGA GATGCATACAACGGCTCGATCAA CCGATCATCTTGACCGGGTTCTCC GCGTTAAACAAACTCCTCGGCCG TGAAGTGTATAGCTCTCACATGCA ACTCGGCGGTCCGAAAATTATGG CCACCAATGGGGTAGTCCATCGC ACCGTCTCCGATGACCTCGAAGG TATTTCGGAAATCCTGAAATGGCT AAGCTGTATTCCCCCTCAAAGCG GCGGGGCAATTCCGGTATTTCCOTT CTCCGGATCCTCCGGAGCGACCOC GTGGAGTACTTCCCAGAAACATC GTGCGACCCGCGGGCGGCCATCT CGGGTACAATGGACGGCAGCGG GAAGAAGTGGCTCGGGGGTATTT TCGACAAAGACAGCTTCGTGGAG ACACTGGAAGGGTGGGCGAGGAC CGTGGTGACCGGGCGGGCAAAG CTCGGGGGGATTCCGGTTGGGAT AATAGCCGTCGAGACTCAAACCG TGATGCAAGTGATCCCCGCCGAC CCGGGCCAGCTGGACTCGCACGA GCGGGTCEGTGCCCCAGGCGGGT CAAGTATGGTTCCCAGATTCGGC GAATAAAACCGCCCAAGCGATTAT GGATTTCAACCGAGAAGAGCTCC CGCTCTTTATCCTEGCCAACTGGCE GAGGCTTCTCGGGCGGCCAACGA GACCTCTTCGAAGGTATCCTACAG GCGGGGTCCACCATAGTGGAAAA CTTAAGGACATATAACCAACCGGT TTTCGTATACATCCCTATGATGGG CGAGCTTCGTGGTGGGGCCTGGGÇ TTGTTGTGGACAGTCAGATAAATT CCGACCACATCGAGATGTACGCT GATCGGACGGCTAAAGGCAACGT CCTTGAACCGGAAGGAATAATCG AGATCAAGTTTAGAACAAAGGAGT TGCTCGATTGCATGAATCGACTCG ACCCAAAGCTGATATCTTTAAAAA CCAAACTAACCGAAGCGAAGAATA GTGGGACCTACGGGATGGTCGAT TCCGTACAACAGCTGATAAAATCC CGGGAAAAGCAACTTCTGCCGCT TTACACGCAAATCGCCACACGATT CGCCGAGCTTCACGACTCGGCTT TACGAATGGCGGCAAAGGGGGTG ATTCGAGAAGTTGTCGACTGGGG GATTTCACGATCTTACTTCTACAA AAGGTTAAGAAGGAGAATCGCCG AGGCTTCGTTGGTGAACACCGTG AAAGATGCAGCGGGTGATAAGCT CCAGCATAAGTCGGCTATGGAGT TGGTCAAAAACTGGTTTCTGGACT CGAAAGGCGATTGGGAAAACGAT GAAGCTTTCTATGCTTGGAAGGAT AATCCCGCGAATTACGAGGAAAA GCTACAGGAGTTACGGGTCCAGA AGGTGTTGCTTCAGTTAACTAACA TTGGCGAGTCTTTGTCGGATTTGA AAGCTTTACCTCAAGGTCTTGCTG CCCTTCTAAATAAGGTAATTTITTTG GGTTTTTTCTTCCAGGAATATTGTT TATTTAGACGATCGAGTCGGATGT TATGTAATACTTTATGTTTGATGTA GGTGGAGCCATCGAGCCGAGGG GCGTTGATCGATGAGCTTCGGAA GGTGCTTAATTGATTTTCGGTAAG TGTTTCTCGGCTACTAAATATGTTT TACTTTGGCTTCAGTCTCTGGGTA GTTTGAATCAATAGAAAATGCCAA TGTGAAAATACCCAGTAATATATTT GATAAGTGTAAATGTAACTATTATT ATATTTAAGTGAATAGGGGGAATT AGTTCATATGATTATTGTTGTTATA AACAAATCAGAGATAGAGAGAGCT ATATTTATTATTATATTTGCGAATT AAAGTTATTAGGAGTAGTATAATTT GGCGGTTGTTGCATTTTACGTGTA ATGATCTGAATGTTGTTTGTTCGT GATTATTGAATAAAAGGGCATCAA ATGCCATAATTTATCTITTCITTITGTT AACAAGATTTTAATTAGTTITTITITT AATTATTAGTATGTTTTGTATA-
ATTTATATT 58 Euphor- |gD- |5227 TATATAAATGTGAAATTGGATAATT bia hete- | NA- CTATATCATTCATCTGAAGCTTATT rophylla | Con- ATGGCCTTTTTTGATCCAGGACAA tig ACTTAAAGGCTATGACAATAGACA
ATATACTCAGTCAAGGGACAGACA ATGGCACATGTACACTGTTGTAGA CAAACCAGTTCCAATCCAGAGGAT GTTTCTAAGAACCCTTGTGAGACA GCCCACAAGTACTTCATATCAAGG TCTTGGCGCCGAAGCACCCAATG TGCAGTGGGCCATGTCCTTTACGT CAAAGAGCATTTTGAGGTCCTTAG TAGCTGCAATGGAGGAACTGGAG CTTCACGTGCACACTGTCAAATCT GACCATGCTCATATGTACCTCTGC ATATTGAGGGAGCAACGGATAGA AGATCTTGTTCCATACACGAAGTA ATTATATCAATCTTTATGATTTATC GTGTACTTGGCACCATAACTTTAT GTGTACTCACTATGAGACTCCATC TCCAGGAAAACCGATGTAGATGC CAACCAAGAAGAAGCTGCGGTAG CAAGAATCTTGGAAGAACTAGCGA GGAAGATACATGCGTCGGTTGGA GTCAGAATGCATAGGTTAAATGTT TGCGAGTGGGAAGTGAAGCTATG GATGACATCATCTGGACAGGCAA ATGGTGCTTGGAGAGTTGTCACAA CAAATGTGACTGGGCATACCTGT GCTGTGCATGTAAGTATCTGCGCA TCTTATTTCAAGAAAATGTCTTTCC CTTCCATGCATTCCTTATTAGTCG ACTTAGTAATGGGGAATGTCGAGA AGTGTTGGATGGTTACCAATGTGA GTACCATCACTGTTTAGATTAAAA TTGACCATTGCTTTAGCAATACAA TAATGAATCTAATTGTGGCATGGG AGGCTTTTCTATGTGTGATCCATG GAAAAACTTGTATATAGTTCCTTA GTAGGTTTGAGTTGTTTTCATTITT CTTTTATCACATTGTAATTGTATTG GTGATTGATACGAAAATTAGATAT ATCGGGAACTTGGGGACGACAGC AAACACGAAGTGGTTTACCATTCG ATCTCTCCAAGAGGCCCACTGCAT AGCATGCCAGTGAATGCTGTTTAT CAGCCCTTGGGAGTTCTCGATCG AAAACGTTTGTTGGCAAGGAAGA GCAACACCACTTACTGCTATGATT TTCCACTGGTTAGTATTTATATAAT CATTAATCAAACATCAGTTTTTITTTA TTGGGGATAACTAAAATCAAATAA TTTTTCCTGGCCTCATCCTTTTCA GGCGTTCGAGACAGCCATCGAAC AATTATGGGAATCTCAATCACCAG GGACTGAAAGAAACAAAGAAAAA GTCCTAAAAGTCTCGGAGCTTGTT TTTGCCGATCAGAAAGGTACCTG GGGAACTCCACTTGTTCATGCAGA ACGGCCAGCTGGGCTTAACGACG TGGGCATGGTAGCATGGTGCATG GAAATGTTCACCCCAGAATGCCCT TCCGGAAGGAAAATCTTGATAGTA GCGAACGACGTGACCTTCAAAGC CGGGTCTTTCGGTCCAAGAGAGG ATGCATTCTTTTCCGCCATAACCOG ATCTGGCATGCACCAAAAAGCTCC CTTTAGTCTACCTGGCAGCAAACT CTGGTGCTCGTATAGGTGTTGCC GAGGAAGTCAAGTCTTGCTTTAAA GTCGGTTGGTCAGATGAGTCATCT CCCGAGCGTGGTTTCCAGTACGT ATATTTGACTCCCGAGGATTATGC AACCATTGGATCATCGGTGATAGC ACACGAGCTGAATCAGAATGGAG AAACACGGTGGGTCATAGATGCC ATTGTTGGGAAAGAGGATGGCTTA GGTGTCGAAAATTTATCGGGAAGT GGAGCCATTGCTAGTGCATACTCA AGGGCATATAAGGAAACCTTCACA TTGACATACGTAACTGGAAGAACA GTGGGAATCGGTGCTTACCTGGC ACGCCTCGGGATGAGATGCATAC AACGGCTCGATCAACCGATCATCT TGACCGGGTTCTCCGCGTTAAAC AAACTCCTCGGCCGTGAAGTGTAT AGCTCTCACATGCAACTCGGCGG TCCGAAAATTATGGCCACCAATGG GGTAGTCCATCGCACCGTCTCCG ATGACCTCGAAGGTATTTCGGAAA TCCTGAAATGGCTAAGCTGTATTC CCCCTCAAAGCGGCGGGGCAATT CCGGTATTTCCTTCTCCGGATCOCOT CCGGAGCGACCCGTGGAGTACTT CCCAGAAACATCGTGCGACCCGC GGGCGGCCATCTCEGGGTACAATG GACGGCAGCGGGAAGAAGTGGCT CGGGGGTATTTTEGACAAAGACA GCTTCGTGGAGACACTGGAAGGG TGGGCGAGGACCGTGGTÇGACCEG GGCGGGCAAAGCTCGGGGGGAT TCCGGTTGGGATAATAGCCGTCG AGACTCAAACCGTGGTGCAAGTG ATCCCCGCCGACCCGGGCCAGCT GGACTCGCACGAGCGGGTCGTGC CCCAGGCGGGTCAAGTATGGTTC CCAGATTCGGCGAATAAAACCOGC CCAAGCGATTATGGATTTCAACCG AGAAGAGCTCCCGCTCTTTATCCT CGCCAACTGGCGAGGCTTCTCGG GCGGCCAACGAGACCTCTTCGAA GGTATCCTACAGGCGGGGTCCÇAC CATAGTGGAAAACTTAAGGACATA TAACCAACCGGTTTTCGTATACAT CCCTATGATGGGCGAGCTTCGTG GTGGGGCCTGGGTTEGTTGTGGAC AGTCAGATAAATTCTGACCACATC GAGATGTACGCTGATCGGACGGC TAAAGGCAACGTCCTTGAACCGG AAGGAATAATCGAGATCAAGTTTA GAACAAAGGAGTTGCTCGATTGC ATGAATCGACTCGACCCAAAGCT GATATCTTTAAAAACCAAACTAAC CGAAGCGAAGAATAGTGGGACCT ACGGGATGGTCGATTCCGTACAA CAGCTGATAAAATCCCGGGAAAA GCAACTTCTGCCGCTTTACACGCA AATCGCCACACGATTCGCCGAGC TTCACGACTCGGCTTTACGAATGG CGGCAAAGGGGGTGATTCGAGAA GTTGTCGACTGGGGGATTTCACG ATCTTACTTCTACAAAAGGTTAAG AAGGAGAATCGCCGAGGCTTCGT TGGTGAACACCGTGAAAGATGCA GCGGGTGATAAGCTCCAGCATAA GTCGGCTATGGAGTTGGTCAAAA ACTGGTTTCTGGACTCGAAAGGC GATTGGGAAAACGATGAAGCTTTC TATGCTTGGAAGGATAATCCCGC GAATTACGAGGAAAAGCTACAGG AGTTACGGGTCCAGAAGGTGTTG CTTCAGTTAACTAACATTGGCGAG TCTTTGTCGGATTTGAAAGCTTTA CCTCAAGGTCTTGCTGCCCTTCTA AATAAGGTAATTTTTTGGGTTTITITT CTTCCAGGAATATTGTTTATTTAGA CGATCGGAGTCGGATGTTATGTAA CACTTTATGTTTGATGTAGGTGGA GCCATCGAGCCGAGGGGCGTTGA TCGATGAGCTTCGGAAGGTGCTT AATTGATTTTCGGTAAGTGTTTCT CGGCTACTAAATATGTTTTACTTT GGCTTCAGTCTCTGGGTAGTTTGA ATCAATAGAAAATGCCAATGTGAA AATACCCAGTAATATATTTGATAA GTGTAAATGTAACTATTATTATATT TAAGTGAATAGGGGGAATTAGTTC ATATGATTATTGTTGTTATAAACAA ATCAGAGATAGAGAGAGCTATATT TATTATTATATTTGCGAATTAAAGT TATTAGGAGTAGTATAATTTGGCG GTTGTTGCATTTTACGTGTAATGA TCTGAATGTTGTTTGTTCGTGATT ATTGAATAAAAGGGCATCAAATGC CATAATTTATCTTTCTTTGTTAACA AGATTTTAATTAGTTTTTTTTAATTA TTAGTATGTTTTGTATAATTTATAT TTGACTAATTAATGAGTTCTTTCTG AATTTATACCAAAATTTCAATATAA TACTGAATTTAAAACTTGAGTCTA GATTACCAACAAGGTGTAGCTCAG TTGGCAACGCAGGCTGGGTAAGT TGGAGGAGAACAATGTTTGAATCC TACTAAATACACTTGTTGGGAGGG GTGATGAGCCTTAACTGTGATTAA GTCCCGAACAAGATTATCTCAATG GTGATACTTGTAATTATTACCAAAA AAAACTTGAGTCTACGATGCAAAT ATGTATTATCTAGGCATGGTCTAA TTAGATTTAAATATGGGCTGATTG GATTTAAATTTCTCTTTTTITAGTA CGATCTTATTAATTCAAATTAGAGT CCATTACATTTCTAATGGATGAGA AACCACGTCCTCCTCTATGTCAAA GAAATAGATGTCTTGGCTAATAAA TGGACAACTTGATTCGTAGACCTA TTAACAAAAACAACTTTTAAACCTA AAAAAGAGGTCATGAGTATTTTGC AATCGAAAATAGTGAAACCTATTG ACGAATGAAGAGGAGAGTTGATC AGAGCATATAGCTCGAGAATGACA CTATCCAAGCCTTGGCTCTTTAGT CAACTGAGCGCCTCTCTGCAACT CATAGCCTCTACTAGAAGAACATC TTGCATGAGAGAGGATTGGGCTG CTACAAATCTACCCATATAATCTC GAATTACACAGCCATTCATCTACC ATTCTCAAACACACTAGCACGTTA CATTTAAATCCAATGTTGTTTTAGC TTTGGATGTTTTGTGTGTCATTAAT GTTTGTTGTCTGCCATTCACTGAG GAACCCCAAACTGTGCCTAATAAC TTGGGAATCAATTCGAAAACGTTG ATTCCAAGCCCAGCTATTCCTTCT GGGACCATATAGTGCACAAAATCA AATCCACCAATCTGTGATGGAAGC TATCGAATATGGCCACCCATTGCT GCAAATGCCCGACCATAACGCGA GAGCAAATGGTCAGGTAACGAGG GCGTGATAAGTCAATGTGTCGTGT CAGCCCCATCACTGCATATAGAAC CAACATGGTCGATCATAATATGCT TATCTTGAAGCCTAACCAACGTTG GTAATGGGAGTCCCACCATCGCT ACTTTCCAAAAAAAGATGAGTACA TGAGCTGGGAATTGGATGTCCCG AATTTTTAGATTAAATATATCAACA TTATAAATTTCTTTTTTITITITTAT AAATTAACATTATAAATTCAATCAA
AATGATAATCGTTCTATGAT [56 Jeeror fo 110 [aTorTAGTTaNTeTTaTTITCASO bia hete- | NA- ACATATCACTTGTGAACTCTCAAG rophylla | Con- TTTCATTGAACATCGAAGGAAGCA tig AATATACGGTATGGTACCTTTCAT
ATTAGTATCTTAAATGAATAAATTT TAGTTTGGTGATGGATGCCATTTA CGTTTGTAAAATCATTGCTAGATT GACATGGTTAGAGGGGGGCCAGG GAGCTATAGATTGAGGATGAATG GATCGGAGATAGAGGCAGAAATT CATACACTGCGTGATGGAGGTTTA TTGATGCAGGCAAGTTGACTCATT AACCATGGCTGTTGTAAACTAATA ATTTTCGTCCTTTTTATCATTTAAT ATTTGCTTTAGTCGACCCTCCATG CTTTGGAGACCATAACAGACTCTA TTCTGTTTCTTCACAGTTAGACGG AAACAGTCATGTAATATATGCTGA AGAAGAAGCAGCCGGAACTCGCC TTCTAATTGACGGGAGGACTTGCT TGCTACAGAATGATCATGATCCGT CAAAGTTAGTGGCAGAGACGCCA TGCAAACTTCTGAGATATTTGGTT TCAGATGGTAGTCATATTGAAGCT GATGCTCCATATGCAGAGGTTGAA GTTATGAAGATGTGCATGCCTCTT CTTTCACCTGCTTCTGGAGTTGTC CATTTTAAAATGTCTGAAGGTCAA GCAATGCAGGTGTGTTTGATTTCA CAAACACATGCTTTTGGGCTTGAT AAGTACATTTTGGTTTTATATGAAT AGTCAGTTTTGATGTGAATCTAAG AAGTTTTCATGTAGGCTGGGGAG CTCATTGCAAGGCTTGATCTTGAT GATCCTTCTGCTGTAAGAAAGGCA GAGCCTTTTCATGGGAGATTCCC GCTACTTGGCTCTCCGACTGCTAT TTCTGGTAAAGTTCATCAGAGATG TGCTGCAAGTTTGAATGCAGCCC GTATGATTCTTGCTGGCTATGATC ATAATATTGATGAAGTAAGTTGCA AGCTGGCTAGTTTCAACATGAACT TAATTGATGAATTAATTGTTCATTC TATATTTTGTTGATTGTGTAATTTC ATAACAAAATAATGAACTGTGCAT TTGGTTTATTATATTGACAATTATT TGTTGAAATCTGATGTAATATCTC AATGACATCTATAGGTAGTGCAAA ACTTGCTCAATTGCCTTGACAGTC CTGAACTCCCTTTCCTTCAGTGGC AAGAGTGCTTGTCTGTTCTAGCAA CTCGCCTTCCCAAGGATCTTAGAA GCGAGGTGAATAATTTTTCTGTAA TTTTTTCATGACCACATAGTCTTCT TGCTCACAATTTGATATTGGCAAT TTGTATAGTTGGAATCAAAATACA CAGAGTTTGAAGGAATTTCAAGCT CCCAGAACATTGACTTCCCTGCCA AACTGTTAAGGGGTGTCCTCGAG GTGGGTTCCTTATTGCATGGCTCT CTTGGAATTTCTCATTATCTGTTTT TTTTGCTGTTTAATGAGATGTGTAT GCTTTTCCTCCAGGCACACCTGAA ATCCTGTCCTGAGAAAGAAAAAGG AGCCCTGGAAAGGCTTGTTGAAC CTTTGATGAGTCTTGTAAAGTCTT ATGAGGGAGGACGTGAGAGTCAT GCTCGAGTGATCGTCCAATCACTT TTTGAAGAGTATTTATCTGTAGAA GAATTATTTAGTGACAACATCCAG GTTAGCTTCTTCCTATCAAACATA ATATGGAATTATTTTGGATTCTGAA AGTCTTCCCTCTTTGGCATCOTTITT AGAAAATTAAGCATAATACTGGGT ACTATATCCATTATTCTTTATAATC ATGAAATTTATTCTTACAGAAGAAA AGTGGAATTTCTATATATATTTAAA CCAAGCTGGCAAGCTTTGAATTCA ATCCTGTTGTTTATTGTTTTATCCA ACATGCCAAAAATATTAGGAACTT CATGTGACTACTTGTATCATTCTTA TTCTGTAATTACAGTAAAGTAACTT GTCATATCCTAATGTTATAACTCG TAACATTCTTCTTTAGGCTGATGT GATTGAACGTCTCAGACTTCAATA TAAGAAAGACCTTTTGAAGATAGT GGACATTGTCCTTTCTCATCAGGT ATCTGATTTTCGGTTTTAATTTTTA TCTCGGGTTTTCTAAAATAGAATT CTGAGTTTGTGGAAATAACTACCG TATTTGTTGGTTTATAGGGTGTTA AGAGTAAAAATAAGCTGATACTAC GGCTCATGGAACAACTTGTTTACC CCAACCCTGCTGCATATAGGGATA AACTCATTCGGTTCTCTCAGCTTA ACCACACCAGCTATTCCGAGGTT GGCAGCTATACTTGGTCCATCTGT AATTTCATAAAGTTGTTGCTCTGTT TCCTTTTGTTCACAAGTTCATTTTT GAGAGTTTTCCATAGGATGGTGAC TGACAGGAAGAGGATTCTAATGTT TTCTCTTGGAGGATTTTTTCTGTAT TTTCATTTCTTGTCGGTCATTGATT AATTCCGTTTCTGGTATCAGTATC ATCAAAATGTTGTCTTTTTCTGTAT ACTGATGCTGAATTATGTGAACAG TTGGCATTGAAGGCAAGTCAACTC CTAGAACAAACCAAACTGAGTGAA CTCCGTTCCACTATTGCTAGAAGC CTTTCGGAATTGGAGATGTTTACA GAGGATGGTGAAAATATGGATACT CCCAAAAGGAAAAGTGCCATTAAT GAACGTATGGAGGATCTTGTGAG TGCTCCTTTGGCTGTTGAAGATGC TTTAGTGGGTCTTTTCGAGCACAG TGATCACACCCTTCAAAGGCGAGT GGTGGAAACTTATGTTCGTAGGCT ATATCAGGTACTGTGTTGTAGAAA CTTAAAACTTTTATCTGGTGATCAA ACACTAGACGAAACTTGATCTTGA TCAACTGTTTGTCTACCGCACCAG CCCTATCTGGTCAAAGGTAGTGTCE AGGATGCAGTGGCATAGATTTGG TCTTATTGCTACATGGGAATTCTT GGGAGAGCATATCGGGAGAAAGA ATGGATCTGAAGGTCAAATGTCAG ATGAACCAGAGGCTAAAAAACAGT CTAATAAGAGATGGGGAGCAATG GTTATCATCAGATCTCTGCAGTTT TTGCCTTCAGTTATTGGTGCTGCA TTAAGGGAAACAAATCAAAGCCTT AATGAGTCCATTCCAAGTGGATTA GTAAAATCAGCGAGCTTTGGTAAT ATGATGCACATAGCATTGGTAGGC ATCAATAATCAGATGAGCTTACTA CAGGATAGGTAACTTCCTTCGGTA CTATAATATAAGCGTTTATTTTAAT CATAAAAATTAGTAGCATTTTACAT TCTATTATTCATTGTAAGATCTCAA GTCTTCTTAATCATTTCTGCATTTG AAACCTTGATAGATCTGGATAGAT TCCTTATTTTTGTTTAAAATTTATG ATAGAGTTACCTGGTCTCGAACCC TTAAAACATGCACATATATTGGCT TGCCAAACATAAGTTATTTTGCGT TGTCAATTTCGATTATTGACAGTC ATCTTGTTAATGCTCCTAACTGGC ACCATCTATGACATTTTGCAGTGG TGATGAGGATCAGGCACAAGAGA GAATTAACAAGTTAGCCAAGATTC TCAAAGAACAGGAACTAGGTTCCA GTTTGAGCTTGTCAGGCGTTGGA GTTATTAGCTGTATCATACAGAGG GATGAAGGGAGAGCCCCTATGAG GCACTCCTTTCACTGGTCAGAGG AAAAGCTTTATTATGAGGAAGAAC CTCTATTGCGACATTTGGAACCTC CACTATCCATCTACCTTGAACTGG TTTGTCACCTATCGCAGTGTTTCA ATACATTTTTTTGGCAGAAACCTTT ATTGAGCCCCTGAACTTACCAGTT TTATTCTCAAGTTATTATTTGACTA CATTAAATACTTGAATTACTATTGA ATCCACATTACGACCTTGAAAACG TTTTATTGATAAAATTATAACTGTT GCTATTTTGTTTTACATATATCAAG GACTGCACTATAGTAAAAAAATGA GGACTCGATATGATTGGAAAGTTC AGGGGCTTACTAATTGTTTGAGCG GAAAAAAATATATATAAATGTGAA-
ATTGGATAA Euphor- |gD- 1523 AAAATATCTTTGTTTCTGTAATAAA bia hete- | NA- TTGTTCTTTGACTTTTCTAATGATC rophylla | Con- TTTAATCTACATCCTAATCTGGAT tig GTAGGTGGAGCATCCCGTCACAG
AGTGGATTGCTGAAATAAATTTGC CTGCTGCCCAAGTAGCTGTTGGG ATGGGAATTCCTCTGTGGCAAATT CCTGGTATGACCGCAAAAGTTGG AAATTCACATTTTCTTGCTCATTAG ACATGTTTCTTTGACATTCTGTTGA TTTTTAATCAGAGATTAGGCGATT TTATGGAATGGAACATGGTGGAG GATATGATGCTTGGAGGAAAACTT CAGTGGCTGCTACGCCTTTTGATT TTGACAAGGTAGACTCTACAAAGC CAAAAGGTCATTGTGTAGCTGTAC GTGTGACAAGTGAGGATCCAGAT GACGGCTTTAAGCCTACTAGTGG AAAAGTACTGGTAAGGTTTTCAGG TTGACTATTCTAATTTGAATTTCCT TCTATTCCAAAATTCCTTATCCTGT AATGAACTTGTACTTTTATTGTCOTT GCACAGGAGCTGAGTTTTAAAAG CAAGCCAAATGTGTGGGCTTATTT CTCTGTGAAGGTGACTTTTTGCTG CTCTCTTTCTTTGGAACATGTTTAT GTTGACACAATTGGTTTCTGACTT AATAACTTCATTCTGATTTGTAGTC TGGTGGAGGCATTCATGAATTCTC AGATTCACAATTTGGTAAGTAATA ATTGCTAAATAATCACACTTCATG GATAATAATGAAAAGAAGTTTGTG AGATGAGTTATCCAATCTGCTGCA AATTAATGGTTCTTTITTTATCTTCOT TGTGACATTTTTTTTAACAAAAGCT ACAGTCTGCTTTTCAGTTTAGTCOT TTTCCGTTTGTTACATTTGCTATCG AAAGCACTCATGATTGTCGTAATC TTTCCTTAGGACATGTTTTTGCATT TGGGGAGTCCAGAGCTTTGGCAA TAGCTAATATGGTTCTTGGGCTGA AGGAAATACAGATAAGAGGAGAA ATCCGCACCAATGTTGACTACTCT GTTGACCTTTTACATGTAAACTAT CTTAGCTGTTGATGTTCCCTTTAT ACATCATGTAAACTTTCACGAGGA ACATGAACACGAGTTGACATGCTA TGCAGGCTTCAGATTATAGGGAAA ATAAAATTCACACAGGTTGGTTGG ACAGTAGAATAGCTATGAGGGTTA GAGCAGAAAGACCTCCTTGGTAC CTCTCTGTTGTTGGAGGGGCACT ATATGTAAGTTGTCACGATTTCAC ATGAGAGGATGACTGTATACTTTT GGAATGCTTTATTATGTCTTTCAG AACTTGCCACTTAAGTGTTCAATT TTTTGTTTGCACCAGAAAGCATCT GCTAGCAGCGCAGCTATGGTTTC TGATTATGTTGGTTACCTTGAAAA GGGCCAAATCCCTCCCAAGGTAC ATCAAAAGTATATTTGTACAATTGT ATATGTTTCTTATTCAGCCGATTAT GTTGATGTTGATGTTAGTT-
GATCTTGTTTTCAG 61 Xanthium |cD- |1349 GTTGTTGTCAAGTCTCTATTTGAG strumari- | NA- GAGTATCTGTCTGTTGAAGAACTC um Con- TTCAATGATAACCTTCAGTCTGAT tig GTTATAGAGCGTCTACGTCTTCAA
CATGCAAAAGACCTTGAGAAGGTT GTACACATTGTGTTCTCGCACCAG GGTGTGAGAAACAAAAATAAATTA ATACTACGGCTTATGGAAGCATTA GTATATCCAAACCCATCTGCTTAC AGAGACCAGTTGATTCGCTTCTCT GCCTTGAACCATACATCTTATTCT GAGTTGGCACTTAAAGCAAGCCA ACTTCTAGAGCATACTAAATTGAG TGAACTTCGAACAAGCATAGCAAG AAGCCTTTCAGAGTTGGAGATGTT TACTGAGGAAGGAGAACGGGTGT CAACACCTAGGAGAAAGATGGCA ATAAATGAGAGGATGGAAGATTTA GTATGTGCTCCACTGGCAGTTGAA GATGCTCTTGTAGCTTTGTTTGAT CACAGCGATCCTACACTTCAGCG GAGGGTTGTTGAGACATATATACG TCGATTGTATCAGCCCTACCTTGT AAGTGGAAGTATCCGGATGCAAT GGCACCGAGCTGGCTTAATTGCT TTATGGGAGTTCTCTGAAGAGCAT CTTAAGCAAAGAAATGGGCACGAT GTGCTTGTACAGCAAGTAGAGAAT CCCATTGAGAAGAGATGGGGTGT CATGGTTGTAATCAAGTCTCTTCA GTTTCTAGCAACTGCAATTGATGC TGCACTGAAGGAGACCTCGCAAT ATAGAGCAGGTGCTGTAAGTGTCT CGAATGGTAACCATGTAAATTCAA ATCAAAGCAATATGCTGCATATTG CTTTGGTTGGTATCAATAATCAGA TGAGTACTCTCCAAGACAGTGGT GACGAGGATCAAGCACAGGAAAG GATCAACAAACTATCCAAAATTTT GAAGGATAATACTATTACATCGCA ACTTAATGGTGCTGGTGTTAAGGT CGTCAGTTGCATTATCCAAAGAGA TGAAGGGCGTCCACCAATGCGAC ACTCCTTCCATTGGTCTGTTGACA AGCTTTATTATGAGGAGGATCCAA TGCTCCGCCACGTGGAACCACCA TTGTCTACATTCCTTGAGCTGGAC AAAGTAAATTTGGAGGGTTACACT GAAGTAAAATACACCCCATCACGT GATCGTCAGTGGCATATTTACACA CTTATCAAGAACAAGAAAGATCAG AGATTAAACGACCAGAGGATGTTC CTTCGTACCATAGTCAGACAACAA AGCGCAACAAATGGTTTCCTGTCA GGAAATATTGACAATGAAGTAGGC CGCACTCAAGCTTCGTCATTCA-
CATCACACAGCATCCTCAG 62 Comme- |cD- /7098 ATGACACTGATTAAATATCTATGTA lina diffu- | NA- GAACGCCTGAAGCCCAGAAGGGA sa Con- GCAGTTATGGCAGATGTCTGGCA tig AGATCATGGGATTTTAAATGGGAC
AGTTCAAGTCAAACATGCAGCTAC AACGTCTGAAGTTGATGATTTCTG TTATGCACTTGGTGGAAAGAGACC TATTCGCAGCATATTGATTGCTAA TAATGGAATGGCTGCTGTCAAATT CATGCGTAGTATTAGAACCTGGG CTTACGAAACATTTGGATCAGAAA AGGCAATTTTGTTGGTTGCGATGG CAACTCCAGAAGACTTGAGGATAA ATGCCGAGCACATTAGAATTGCTG ATCAATTTGTAGAGGTTCCCGGTG GAACCAATAATAACAATTATGCAA ATGTTCAACTCATTGTGGAGCTGG CCGAAATAACACGTGTTTCTGCAG TTTGGCCTGGATGGGGCCATGCA TCCGAGAATCCCGAACTTCCAGAT GCCCTGAATGCAAAGGGAATAAT CTTTCTEGGGCCTCCAGCTGCGCE CAATGTCAGCACTAGGTGATAAAA TTGGTTCTTCTCTAATTGCTCAGG CAGCAGGTGTACCAACTCTTCCGT GGAGTGGCTCACATGTCAAAATTT CAGCGGAAAGTTGTATGGACACA ATACCCGAAGAGATATACAAGCAG GCTTGTGTTTATACAACAGAAGAA GCAGTGGCCAGCTGCCAGGTAGT TGGCTATCCTGCCATGATAAAGGC ATCTTGGGGCGGTGGTGGTAAAG GAATAAGAAAGGTTCACAATGACG ATGAAGTGAGAGCTCTCTTCAAAC AAGTGCAAGGAGAAGTTCCAGGA TCTCCAATATTTATAATGAAAGTG GCATCACAGAGTCGTCACTTGGA AGTTCAGTTGCTTTGTGATGAATA TGGCAATGTTGCTGCTCTTCACAG TCGAGATTGCAGTGTTCAAAGGC GACACCAAAAGATCATCGAAGAA GGTCCGATCACGGTGGCCCCTCC TGAGACAGTCAAACAACTTGAGCA GGCAGCAAGAAGGCTTGCTAAGT GTGTTGGTTATGTTGGTGCTGCTA CTGTTGAATATCTCTACAGTATGG AAACTGGTGACTACTATTTCCTAG AACTGAACCCTCGATTACAGGTTG AGCATCCTGTAACTGAGTGGATAG CTGAAGTCAGCTTGCCTGCGGCT CAAGTTTCAGTTGGTATGGGCATA CCACTATGGCAAATTCCAGAAATC AGAAGATTTTATGGAAAGGAGCAT GGTGGAGGATATGATGCTTGGAG GAAGACATCACTTTCTGCAAGTCC TTTTGACTTTGACAAAGCAGAGTC TACAAGGCCAAGAGGTCATTGTGT AGCTGTTCGTGTGACGAGTGAAG ATCCAGATGATGGCTTCAAGCCCA CCAGTGGCAAAGTGCAGGAGCTA AATTTTAMAAGCAAGCCTAATGTG TGGGCATACTTCTCTGTTAAGTCT GGTGGTGGCATCCATGAATTTTCT GATTCTCAATTTGGACATGTTTTT GCATTTGGGGAATCTAGAGCCTT GGCGATAGCTAACATGGTTCTTG GACTGAAGGAGATCCAAATTCGT GGGGAAATTCGAACAAATGTTGAT TACACAATTGATCTATTAAATGCAT CAGAATACAGAGACAACAAAATCC ACACTGGTTGGCTGGATAGCAGA ATAGCAATGAGGGTCAGAGCTGA GAGGCCTCCATGGTACCTTTCAGT TGTTGGAGGAGCTCTTTATAAAGC AACAACTAGCAGTGCTGCCATTGT TTCCGAATATGTTGGTTATCTTGG TAAAGGTCAAATCCCACCAAAGAT TGAAATGGTTCGAGGTGGACCTG GTAGTTATAAATTAAAAATGAATG GTTCAGAGATTGAAGCTGAAATTC ATACTCTCCGTGATGGTGGACTTC TGATGCAGCTAGTTTCAGTGGCAA AGCAAGCATTCCAATATGCTAAGC CTGTTAACAGTATTGATGCTGCTG TAAAATTGCCCCGTATGAATTTCC AGTCTTCTTCATACTCTATITTITCOT TAATAAGATAATGTACCGACAACT TGATGATGGAAGCTTTTTGGATGG AAACAGCCATGTGATATATGCTGA AGAGGAGGCTGCTGGTACACGCC TTCTTATCGATGGAAGGACTTGCT TGTTACAGAATGATCATGATCCAT CGAAATTGATTGCGGAGACACCAT GCAAACTTCTTCGCTACTTGATTG CTGATGGAGAGCATCTTGATGCT GATGCACCATATGCAGAGGTCGA AGTAATGAAGATGTGCATGCCCCT TTTGTTACCTGCTTCTGGAGTTAT TCATTTTGTGATGTCTGAAGGTCA GGCTATGCAGGCTGGTGACCTCA TAGCAAGGCTCGACTTAGACGAT CCATCTGCTGTAAGAAGAGCTGAA CCATTCAATGGTACATTCCCTAAA GTAGGTCCTCCCACTGCAGTTTCT GACAGAGTTCACCAGAGATGTGC TGCAAGTTTGAATGCTGCACGCAT GATTCTTGCAGGATATGAACATAA TATTAATGAAGTTGTTCAAGAGTT ACTACATTGTTTGGATAGTCCGGA GCTTCCTTTTCTACAGTGGCAGGA AAGTATGTCTGTATTGGCAACTCG CCTGCCGAAAGAACTTAAAAATGA GTTGGATTCTAAATACAAAGTATTT GAAACAAACTCAAACGTTCAAAAG AATGTGGAATTTCCTGCCAAGCTT CTGAGTGGAGTTATTGAGAGCTAT CTCTCATCTTGTAGTGAGAAAGAT AAGGCGGCACAGGAAAGGCTTGT GGAACCACTTCTGAGCCTTGCGA AGTCATACGAAGGTGGAAGAGAA AGCCATGCTCGTGTAATTGTGCAT TCTCTTTTTGAAGAGTACTTATCTG TTGAAGAGTTATTCAGTGATAGCA TTCAGGCCGATGTCATAGAACGC CTACGACTTCAATACCAGAAGGAT CTTCTGAAAGTTGTAGACATAGTG CTGTCTCATCAGGGTGTTAGAAGT AAAAATAAGCTGATACTGAGGTTG ATGGAAGCATTGGTCTATCCTAAT CCTGCTGCCTATCEGGGAACAACT GATTCGCTTCTCTGCTCTTAACCA TACCACTTACTCCGAGTTAGCATT GAAAGCCAGTCAACTCCTTGAACA AACTAAATTGAGTGAGCTTCGAAC AAGCATTGCCAGAAGCCTTTCCGA GCTAGAAATGTTTACAGAAGAAGG TGAACGTCTATCTACACCGAGAAG GAAAAGTGCTATCAATGAGAGGAT GGAGGATCTTGTAAGTGCTACGC TGGCCGTTGAAGATGCACTTGTGT CTTTGTTTGATCACACTGATCCAA CTGTTCAGAGACGAGTGATGGAA ACATATGTCCGAAGATTGTACCAG CCCTACCTTGTGAAGGATAGTGTC CGAATGCAGTGGCACCGTTCTGG TTTGATCGCGACATGGGAATTCAC CGAAGAACATATTGAGAAAAAGAA TGATTCTTCTACACAAGATAAGTC ATTTATGGAGAAACATTGTCAAAA GAGATGGGGAGCTATGGTTATCG TCAAATCTCTCCAGTTTCTTCCAG CAGCAATTAGTGCAGCATTGAAG GAAACCAGTCATCTGTCATCTGAT ACTGATCATGATACAGTATCTAAT GGGCTTCCTCAACATGCTAGTCAA GGCAATATGCTTCATGTTGCATTG GTTGGCATTAACAATCAAATGAGT ACACTTCAGGATAGTGGAGATGA GGATCAGGCTCAGGAGAGGATAC ACAAGCTTGCCAAGATTCTAAAAG ATAACAAGGTAGCGACTGAACTTT CCAATGCTGGAGTCCGAGTTGTTA GCTGTATTATACAAAGAGATGAAG GACGAACACCTATGCGTCACTCCT TCCATTGGTCTGCCGATAAGCAAT GCTATGAAGAAGAACCCTTGCTTC GTCATCTGGAACCTCCTCTGTCTA CTTTCCTTGAATTGGATAAGCTGA AAGGCTACAAAAATATACAATACA CACCATCACGGGATCGCCAGTGG CATATGTACACAGTTCAAGAAACT AAACCACTTAATCAGAGGATGTTT CTGAGGACCCTTGTCAGACAACC AAGGATAAATAATGGATTTTCATC AAACCAGCTTCCCGAATTAGAAAC TAGACATGATTTATCCTTTACATCA GTCAGCTTGTTGAGATCTTTGATG GCAGCATTGGAAGAGTTAGAACTA CATGTCCATAGCGAAACAATCAGA TCTGATCATTCTCACATGTATCTCT GCATATTACAAGAACAACAACTCT CCGATCTTTTACCTCGTTCAGGTA CTCTTGATCCTGATGCCTATCAGA ATGAAAGTCAAGTGTCCCTGCTTT TAAAAGATATGGCTGTCAGGATTC ATGAGATAGTTGGTGTAAGGATGC ATCGTCTTACTGTTATTGAGTGGG AGGTAAAGCTCTGGTTGGGTTCET GATGGTGTTGCTGGTGGTTCTTG GAGGGTTGTGGTGACAAATGTTA CTGGACGTACATGTAATGTCCATA TTTACCGAGAATTGGAGGACAGC AAATCACATGAAGTGGTCTATCAC TCTGCAGCTTCAGTCACAGGACCT CTCCATGGTATGCCGTTGATTGCT AGATATCAGCCACTTAGTGTTATT GATAAAAAACGATGGGTGGCAAG AAGGAGCAACACTACTTATTGCTA TGACTTTCCACTGGCGTTTGAGAC AGCACTGAAGCAGTCATGGGCTT CTTATAGTGATACTAAAGCACCAG AAAGCAAAGCTCTTCTCCAAGTTC AAGAACTTATGTTTGTTGACAAAA AGGGATCATGGGGTACTCCTGTT GAACCTGTATGCTGCCCACCTGG TCTCAGTGATATTGGCATGGTTGC TTGGTCAATGGAAATGTACACACC AGAATTTCCCGAAGGAAGGAAGA TTGTTGTTGTAGCCAATGATTTGA CTTTCAAAGCAGGCTCCTTTGGGC CTCGTGAAGATGCATTTTTCCATG CTGTAACCAATTATGCATGTGATA AGAGGCTCCCTCTAATCTATTTGG CAGCAAATTCTGGCGCCAGGATT GGTGCTGCTGAAGAGGTCAAGTC TTGCTTTAAGGTTGGATGGTCTGA TGAGTCGAGTCCAGAACGTGGTT TTCAGTATGTGTATCTGACACAGG AGGACTATAACCGTATTGGTTCAT CTGTTATTGCACATGAACTGAAGC TTGAAAGTGGTGAGATCAGATGG GTGATCGACACAATTGTTGGCAAA GATGATGACTTGGGTGTTGAGAA CCTCACTGGCAGTGGTGCAATTG CCGGTGCTTATTCCAGGGCTTATA ACGAGGTATTTACTCTTACATATG TGACTGGACGTACTGTAGGAATC GGAGCCTATCTTGCTCGGCTTGG CATGAGGTGTATCCAGAGGCTAG ACCAGCCTATAATCCTAACAGGGT TTTCTACACTCAACAAGTTGCTTG GCCGTGAGGTGTACAGCTCACAC ATGCAACTAGGTGGCCCGAAGAT CATGGCTACAAATGGTGTTGTTCA TCTGACGGTATCAGATGATCTTGA GGGCGTTTCTGCTATTCTTAAGTG GCTTAGTTACGTACCACCCTATGT CGGTGGGCCACTTCCAATAATAAA ATCCTTGGATCCCCCAGAAAGGC CAGTGGAGTATTTTCCTGAAAATT CATGTGATCCACGGGCCGCAATT TGCGGCATTGATGATGGCAATGG CAAGTGGTTAGGTGGTATGTTTGA TAAAGATAGTTTTACGGAGACATT AGAAGGTTGGGCAAAGACGGTGG TCACCGGAAGAGCAAAGTTGGGT GGAATTCCAGTAGGAGTTATAGCT GTCGAGACACAGACTGTGATGCA AGTCATTCCTGCAGATCCTGGTCA GCTTGATTCCCATGAACGTGTTGT CCCACAAGCTGGTCAAGTTTGGTT CCCTGATTCTGCCACCAAAACGG CACAAGCATTATTAGACTTCAATC GTGAAGAATTGCCACTTTTCATAC TAGCCAACTGGAGAGGATTCTCA GGCGGACAGAGAGATCTCTTCGA AGGTATACTTCAGGCTGGTTCCAC AATCGTCGAAAACTTAAGGACATA TAAGCAGCCTGTATTTACCTACAT CCCAATGGCCGGGGAGCTTCGTGE GTGGTGCATGGGTTGTGGTGGACÇ AGCAAAATCAACCCGGATCACATC GAGATGTATGCCGAAAGAACAGC AAGGGGCAACGTACTTGAGCCCG AAGGAATGATTGAGATTAAGTTCA GAACTAAAGAACTTCTCGAGTGCA TGGGTAGACTTGATCCTGAGCTAA TCAGTTTGAAAACAAAGCTTAGGG AGTTGAAGGCAGCTGGACCTTCC AGAGATGTGGACGTCCTCCAGAA AAGTGTAACGGCTAGAGAGAAGC AGTTATTGCCTGTATATACACAAA TTGCTATAAAGTTTGCAGAGTTGC ACGATACATCCTTGCGAATGGCTG CCAAAGGTGTGATCAAGAAAGTG GTAGACTGGGAGAACTCCCGTTC TTTCTTCTACAAAAGGTTAAACAG GAGAGTTTCCGAGGATGTCCTTG CAAAAACTGTTAGAGATGCTGCTG GGGAGCAGTTGTCGTACAAGTCT GCTATTGAACTGCTTAAGCAGTGG TTTTCATCTTCCGACAATGTGGAC GTTGGAAAATGGGAGGAAGACGA TGCTTTCCTTGCCTGGAAAGACAA CCCTAAAAATTATGCCAAGTATCT TGAAGAGCTACGAGTTCAGAAGAT ATTGCAGCAGCTCTCAGCTCTTGG TGAATCATCTTCGGATTTGCGAGT ATTGCCTCAATGTCTTGCTACAGT CCTTAGCAAGGGCAGAATAACAAA CTCAAGCGAATCGGAGAAGAGCA GGACCGAGCACGAGATCTGGTCG ACTGAGCTTGAGTGGGCCAAGCT TAAGCTTGCGATGGAGAAGAAGT GCGCCAGAGAAGAGGGGCACAC CTGGATAAGGAAGGCGAGATACA CGAGCATGACCAAATCGAAAATGA GCTGGAGGGGAAGGGAGGAGGA GAATAAGGGAGACATGAGAG-
GAGGGGAAGGATAA 63 Comme- |gD- |14748 | AMAAAAAAAAAAAAACAAAGATCT lina diffu- | NA- TATGATAGTCTGAAAACAAACTTT sa Con- GACCAGTGTGATTTTATGTTAAGT tig GTATTTACCTATCTTTCAATTGACT
TTTCAGGTTCACAATGACGATGAA GTGAGAGCTCTCTTCAAACAAGTG CAAGGAGAAGTTCCAGGATCTCC AATATTTATAATGAAAGTGGCATC ACAGGTGAGATAAATGTATTTTTA AAGCTTCAGTTATGTCATGAATTT ATATGGCCCTGCATTAACTGAATC TAGACTATGCCCAATATGAAATTA TTGCAGGTTACTTTAAGCAGAATA TATGTTTGACAGTAAGTAGGCTGA CTTAGTACTGAACAATTGAGTGTA TCAATGCATGCCCAATATAATAGT GTGTTTCATTTCAGGATAAAAAGT GAGATGTAGTTTTCGGATTCAACA TATGCATTCTTTTTCAACCTTGATG TCATCAGTCAATGCATAGTAGTGC ATGTACTTGACTTTGTGTATGTAAT TATTATTCTTTGGTAGTTGCAATTA AAGGATGCATTGATACACCCAATT GTATCATCAGTTATTTTGCAATTCA TATTCCACCCTTCTGTTTTTAGGA AATTCTAGAAACTTTTAACTTGGAA GCTCTAGAATACCATATCTTGCTT TATATCATGGCAGTTACACTGAAG CTTTATGTTACATGTGCATTCATTT TTAACGCTCCAATATTGTTATCCTT TTATTTCCTCTAGAGTCGTCACTT GGAAGTTCAGTTGCTTTGTGATGA ATATGGCAATGTTGCTGCTCTTCA CAGTCGAGATTGCAGTGTTCAAAG GCGACACCAAAAGGTAAACTTTAG TAAAGCATCTATATAATTATGTTAT TTGTAACCTTTCATGCTTACCTTTA TATTTCATAGACCTGAACCATGTC TATGAATATATTTGTGTGCTGTTAT GAGCAGGTTATTTTTCTCCAGATC ATGTATCTTTATCCTGAACTCTTGT GGACTTATCTTGAATTAACATTTTG TAAATATTTCAAGACTTTCTTCATG ATGCTTATTTATTACCCAACAGAT CATCGAAGAAGGTCCGATCACGG TGGCCCCTCCTGAGACAGTCAAA CAACTTGAGCAGGCAGCAAGAAG GCTTGCTAAGTGTGTTGGTTATGT TGGTGCTGCTACTGTTGAATATCT CTACAGTATGGAAACTGGTGACTA CTATTTCCTAGAACTGAACCCTCG ATTACAGGTTTGTCTITTGCTTGTT GGCTGAAGATTCATTGTTCATCAG AACTTTGTCTTCTAAGTCTTGGTC CTTTTCAGGTTGAGCATCCTGTAA CTGAGTGGATAGCTGAAGTCAGC TTGCCTGCGGCTCAAGTTTCAGTT GGTATGGGCATACCACTATGGCA AATTCCAGGTATGAACTTGTAAGG GAATTTTGCATAATTAATGCAAAAA GCTTAAGAGAAAAAGATGTAAGTT TCTTGTGATGCTAACTCTAGTTAT AATTTTGGTTTCTTTCTTTCAGAAA TCAGAAGATTTTATGGAAAGGAGC ATGGTGGAGGATATGATGCTTGG AGGAAGACATCACTTTCTGCAAGT CCTTTTGACTTTGACAAAGCAGAG TCTACAAGGCCAAGAGGTCATTGT GTAGCTGTTCGTGTGACGAGTGA AGATCCAGATGATGGCTTCAAGC CCACCAGTGGCAAAGTGCAGGTA AATGTTGTTGAATATAGGATATTTA GGCTTAATATTTTCTGCAGGGACA CTGACCAACTTTACTGAACTGGGA CTTAAATATTTTCAGGAGCTAAATT TTAAAAGCAAGCCTAATGTGTGGG CATACTTCTCTGTTAAGGTATGTT GTTTAAGTTTTTCTGGGCTGGCTG CCCTTCTTTGGGTTATTTCTITTGAT TTCTATCAATTAATGTACAACAACA AAAAAAATCTTTTAAGAGTTAATAT AAACAAATGTTGGAAACAAATGTT CTGGCTAAGGAGATCAAAATATAA ACTTTTGTGGAAAAAAGTTGTGTA GTTTGCAATATGAATACAGTGTGA TACTTAGTTGATTGTGTCTTCATTT TTGTCCTAATTAAATTATATTITTGT AATTATTAGACTAAATGTGCTTATA CAGACAAATATTTTGTTTGCAGTC TGGTGGTGGCATCCATGAATITTTC TGATTCTCAATTTGGTATCTCCTT GACAATGAAAGAAGTTAAATTCTT TTGAATGCTGTGAAAAACTCTTCT TAATATTTCCTATTCTTCTCAGGAC ATGTTTTTGCATTTGGGGAATCTA GAGCCTTGGCGATAGCTAACATG GTTCTTGGACTGAAGGAGATCCAA ATTCGTGGGGAAATTCGAACAAAT GTTGATTACACAATTGATCTATTAA ATGTAAGCTCTTGATCTTCTTGTTA CCTCTAATCCAACTTATTGCAATT GCACGTCTTTGTTCTCATCCGCTG CCTCACAGGCATCAGAATACAGA GACAACAAAATCCACACTGGTTGG CTGGATAGCAGAATAGCAATGAG GGTCAGAGCTGAGAGGCCTCCAT GGTACCTTTCAGTTGTTGGAGGA GCTCTTTATGTAAGAATCGAAGCA TAATGTAATCTAGTTATAGTTCTG GTAGGTTAAGTTGTTATTTATATAC TTGACTTATTTTGTGTCTTCAGAAA GCAACAACTAGCAGTGCTGCCATT GTTTCCGAATATGTTGGTTATCTT GGTAAAGGTCAAATCCCACCAAA GGTATAATGCATCCCAGCTGTTTA TGTCGTATTTTATTTTCTTCGATTA GTTCATTAACAAGGAAAAGCAATG CAGCACATTTCGCTGGTCAAAACT CTTGTGACTCTGAATATTGAAGGG AGCAAATACACGGTAAACTTCACT ATTTCCAAAAGTTTTCATTCTTAAT TTTCTTTCAAGAGACACTTCACCT AAACTCCTTGCTGAATGTTTCTTA GATTGAAATGGTTCGAGGTGGAC CTGGTAGTTATAAATTAAAAATGA ATGGTTCAGAGATTGAAGCTGAAA TTCATACTCTCCGTGATGGTGGAC TTCTGATGCAGGTAAACTTTCTAA ATCATCATGTTCCATTGTGTATTTT TTTTATTTTAAACAATGACTAGCTA GTTTCAGTGGCAAAGCAAGCATTC CAATATGCTAAGCCTGTTAACAGT ATTGATGCTGCTGTAAAATTGCCC CGTATGGTCCATGAGAGTACAAAT GGTATTACCATAGTGATCTGATTG TTCATTTGCATTTGATCTAACTTTC CAGAATTTCCAGTCTTCTTCATAC TCTATTTTTCTTAATAAGATAATGT ACCGACAACTTGATGATGGAAGCT TTGTAAGTACCTGAAAATTTTITTAG GTATTGGTTCTGATTTCAGCACTA AGGTTTATACCATAAACTTCAATA CTAAGTGGTCAGTTAAACTTTGGA TCTTTGCACATCAGACTTGTCAGA ACTGTTTTGTTTACAATCATCCACA ATTGGTTATGGGGTGATAATTATG GATGCTTTGTGATTGTTGGCCATC CTGCTGCTCAGAAATTATCTTGAA CTTTATTTGCCCCCAAATTTGAAT CATCTTTTTTTTGGGAATTCTCTTT AGTTTCTTITCTTTCTGCACCAATG TTTTTGTTCTACATGCCCATATTGA CTGCACTTGTGCACAACTGCACGT CTGCACGTCTGCACGCATATATCA CTCTAGGAATACAGTTGATATTCT CAATTCTCGATCTTGTCATATGGT TAAAGTAATTTAGCAGTTCAGATC TTGAACATATTTAATTTCTAAAACT CTATGAAATTCATACAGTTGGATG GAAACAGCCATGTGATATATGCTG AAGAGGAGGCTGCTGGTACACGC CTTCTTATCGATGGAAGGACTTGC TTGTTACAGGTAGAAACAACTTAT ATATTTTTCAAAATTTTTAGTTTCTT GAAGGAAATTAAATTTATTTATTAT CTGCTAGTAGAATTAATGTAAGGG ACCTTTTATGATGTTTTGACATTAT ATATTGAAGGTTCTTTGATTTATTA AAAAATGCATAAGATAGATAGATT GCAGTATTGCACTTTGCATCTTTC AAGTGCGCTTATGCTCAACATGCT TAAGGTGCTTACTGCTTAGATTGC CCAGTGCTGCTCAAAACTTGCATA GAACTGTGAAAACCATTATTTCTTT TGTTCTATCCCTAATGTGAAAGCT TCTGTGCGCCTGCTCCGGCCCTA CTCTAATCTTCATTAGCTTCTTTGC ACTGATTTATGTGATATTTTCTTGG ACTGTTCATGGTCCTTGCTAAGAG TTCCTAAGTATCTGATGTTTGTTTA TGTTAATTTTTGCATTCCATTCCTT TTTAGTTCTAAATGATTGTTTCTAT CGGTCAAACTAAATGCTGCAACTT AGTTATCAGTTGCACTCACCCTAT TCAAATGAAATTTAAGGTACATTTC ACAAATGGGATTAACACATTAAAA ACACTTTATGTGTTAACATGCTAC TATTAGAAATCCAGATATGTTATTT CAGAATCATAAAGCAACGTTAGAT GGCTTCATAAACTGTGAATAAGTG GTAAAGAATTCCTTCCTAGATATT ATTGAAGAAAGTTTCTCTTGAACA AGTTACCTTAAATAATTAATCATAA CTGGTTTTGTCTTCAGAATGATCA TGATCCATCGAAATTGATTGCGGA GACACCATGCAAACTTCTTCGCTA CTTGATTGCTGATGGAGAGCATCT TGATGCTGATGCACCATATGCAGA GGTCGAAGTAATGAAGATGTGCAT GCCCCTTTTGTTACCTGCTTCTGG AGTTATTCATTTTGTGATGTCTGAA GGTCAGGCTATGCAGGTAAGTAA ACCTTGTAAAGATTAGAAAGAAAG TTTCTCTTGTGTTTTCTCATAAACT ACATAGAATCTTGTTTTTGCAGGC TGGTGACCTCATAGCAAGGCTCG ACTTAGACGATCCATCTGCTGTAA GAAGAGCTGAACCATTCAATGGTA CATTCCCTAAAGTAGGTCCTCCCA CTGCAGTTTCTGACAGAGTTCACC AGAGATGTGCTGCAAGTTTGAATG CTGCACGCATGATTCTTGCAGGAT ATGAACATAATATTAATGAAGTAA GGGCTAACGATTAAACTTTTITITT ATTCTTTGTTATTTTTAATTAATTCA AAGTGCTATCTACTTTTATTTCTIT ATACTTTAAGTGGCATTTCTATTAA CTAAAACATATGTTTTTTACTACCC TTTGCCAATGTTGATTAGACCAAA ATGGGTTTAAACTCTTTTATGATG CATTCTAATAATCTTTATTTGCTGA ACCTTTTTAGTTACTTTCAAATTTA TGTAGAGATTAAAGCTTTITTATTCG AAAACGCCACCATACATACACCTC ATCCTTGGAAAATGGAATGTATAC AATTTGCTGATTTTAGTTCCATCAA ATCCCAGTTTAGTCACAAGGAATC ATGCTGATAAGATGCTAAATTTGT GCTACCATGTGCAGTGATCCATGT CTGCAGCTTTGTATATATGCCTTG TGGAGATTAGACGTCCATTTGTCT TATCTTTTTAGTTTCCCCACCTTCA ACTTTGGTGACCGCTGCCCTTAAT GTTTATTTTAAGGAGAAGCATCAT GCTTTTGAGAAATTGGTTGCTTCT ATCAGATGACTGAACACCTTTTTA TTTTTATATATCTTGTTCTAATCAT GCTAAGTTTCATTGAATTTCTCOTTT ATGTTTTCCAATTTTAAACTGATGG TTATGCTATGCCAAAGTGACTAGG CTCTATTGTAATTTTAACTGCAAAG GGACTATTTGATGATTGACACTTT ACTTTTTGTTTTAATTCTTTTAGTTT ACCATTTTATATACTTGTTACTTAT ATGAACTGCAACTTGCATTACTGT ATACAATTTTAAAATTGTTTCTTTC CTTTATGCATATACTGGTTTGCATT TTTTTCTCTAACGTCCCAAGTATAA ATAGGTTGTTCAAGAGTTACTACA TTGTTTGGATAGTCCGGAGCTTCC TTTTCTACAGTGGCAGGAAAGTAT GTCTGTATTGGCAACTCGCCTGC CGAAAGAACTTAAAAATGAGGTTT GTGCATAGTTCTTAATTTTITGTCA GAAGCACATAGTCTAGTTTCCAGT TGGACAGTTGGATTGTACATTTCC CAAATTTAATAATTTTATGTGCAAT TTCTTATTTGATACAGTTGGATTCT AAATACAAAGTATTTGAAACAAAC TCAAACGTTCAAAAGAATGTGGAA TTTCCTGCCAAGCTTCTGAGTGGA GTTATTGAGGTTAGTATGTTTTAG TATGAATATCACTCAAATAATAAG GTTTTAAAACTTTATTTCCTCGATC TGCAGAGCTATCTCTCATCTTGTA GTGAGAAAGATAAGGCGGCACAG GAAAGGCTTGTGGAACCACTTCT GAGCCTTGCGAAGTCATACGAAG GTGGAAGAGAAAGCCATGCTCGT GTAATTGTGCATTCTCTTTITTGAA GAGTACTTATCTGTTGAAGAGTTA TTCAGTGATAGCATTCAGGTGATT GTTTATCCGAAGTTCATTCAAACT TTTTCGACTAACTCTTCCATCAAAA TAAATACTAAAGGAACAAAACTGA TTCTCAATGTTTTTGAAAGTTTCGT TGCTCCAGCTAGATTTTCCAAAGG CCTTAACCATGCATTTTTCTTGTAT AGGCCGATGTCATAGAACGCCTA CGACTTCAATACCAGAAGGATCTT CTGAAAGTTGTAGACATAGTGCTG TCTCATCAGGTATATTTGCAACGT CTGAAGTTGTTTTATTTTACTCCAT AGAATTGACCAATTCTCCTTAAAG TAACATGAATGCTGATAATTCACC TTTTAGTTTCTCTGTGGATGAGAT ACATCTCGTATGCTAGTTTTTCCA TTAACAATATGCCGTTTTTGTITTAC TAAAGGGTGTTAGAAGTAAAAATA AGCTGATACTGAGGTTGATGGAA GCATTGGTCTATCCTAATCCTGCT GCCTATCGGGAACAACTGATTCG CTTCTCTGCTCTTAACCATACCAC TTACTCCGAGGTCAATAATCTTAC TGGATATCTTGCACCTATCCCTTC ATGTTTGTAATTCTTTTGCTCACAT TGGCCTATCCTTACTCGTGCTTGG TCAATATGGTTCCTGCAGTTAGCA TTGAAAGCCAGTCAACTCCTTGAA CAAACTAAATTGAGTGAGCTTCGA ACAAGCATTGCCAGAAGCCTTTCC GAGCTAGAAATGTTTACAGAAGAA GGTGAACGTCTATCTACACCGAG AAGGAAAAGTGCTATCAATGAGAG GATGGAGGATCTTGTAAGTGCTAC GCTGGCCGTTGAAGATGCACTTG TGTCTTTGTTTGATCACACTGATC CAACTGTTCAGAGACGAGTGATG GAAACATATGTCCGAAGATTGTAC CAGGTACCAAACTGAAGTAATATG GTAACAAACATGTAGCTGTTAAAT ATTTATCTGACACTGCTTTTITTCTC AGCCCTACCTTGTGAAGGATAGT GTCCGAATGCAGTGGCACCGTTC TGGTTTGATCGCGACATGGGAATT CACCGAAGAACATATTGAGAAAAA GAATGATTCTTCTACACAAGATAA GTCATTTATGGAGAAACATTGTCA AAAGAGATGGGGAGCTATGGTTA TCGTCAAATCTCTCCAGTTTCOTTC CAGCAGCAATTAGTGCAGCATTGA AGGAAACCAGTCATCTGTCATCTG ATACTGATCATGATACAGTATCTA ATGGGCTTCCTCAACATGCTAGTC AAGGCAATATGCTTCATGTTGCAT TGGTTGGCATTAACAATCAAATGA GTACACTTCAGGATAGGTAACTTA ATTATTCTTGAATATTTCCATCATA TGGTATGTTTGTGGTAATTTGATC ATTTAGTTATGAAAGGTGCAGTCT TGTGCTTATCTTTGAATCTTTTTAA TGGACAAATGTTCCTTGATCATAT TACAGTGGAGATGAGGATCAGGC TCAGGAGAGGATACACAAGCTTG CCAAGATTCTAAAAGATAACAAGG TAGCGACTGAACTTTCCAATGCTG GAGTCCGAGTTGTTAGCTGTATTA TACAAAGAGATGAAGGACGAACA CCTATGCGTCACTCCTTCCATTGG TCTGCCGATAAGCAATGCTATGAA GAAGAACCCTTGCTTCGTCATCTG GAACCTCCTCTGTCTACTTTCCOTT GAATTGGTTGGTGAATGTTTTTAA CTTATTTTATTCACATCTTTATTGT AATTCCCTTTCTCTGATTAATGCC ATTTGTTATTGATTCCATTGCAGG ATAAGCTGAAAGGCTACAAAAATA TACAATACACACCATCACGGGATC GCCAGTGGCATATGTACACAGTTC AAGAAACTAAACCACTTAATCAGA GGATGTTTCTGAGGACCCTTGTCA GACAACCAAGGATAAATAATGGAT TTTCATCAAACCAGCTTCCCGAAT TAGAAACTAGACATGATTTATCCT TTACATCAGTCAGCTTGTTGAGAT CTTTGATGGCAGCATTGGAAGAGT TAGAACTACATGTCCATAGCGAAA CAATCAGATCTGATCATTCTCACA TGTATCTCTGCATATTACAAGAAC AACAACTCTCCGATCTTTTACCOTCE GTTCAGGGTAAGTCTTGTTGTCTA GTTAGTTTGGTGTATTCTTCTGAA AAATGTTTGTTTGTAGATTAAAAAA AAAATGTAGTGTTTTTGGCTAAAC TGATTTCTCCTTTGCTTTGGCTAA AACATTTTTTGGAAGTTTCCATGTT TTTGGAAATTATTCTTTAAGGGCT GTTTGGATACCTATAATGAGGGTT ATAATGTGGATACTTGTAGTTAGT GATTTTAGTGTAGTTGGAAAGTAA AACATAGGTGGTAAACTACATCTC AACATCTCCAAATTTGGTGTTGTT GCTATGATGTAGTCACATGACGTG CCAATTTTGGTGTAGTTCCCAAAA TTTTTTTTAGGTAAAATATATTTAC AAATATCGCACAAGTTTATTCATCT ATTAGTATTTCGTGTAAAGATATCT ATAAAATTAAGCAAACAATGAAGT TGTAGTTCTTTTCAACTATAGCTAC ATGCACTATCAACTAGAACTACAA GCATCCATGTCACAATGTTCATTA AGTTAAATAATATAATTTTAAAATA ATTTTTATTTATTTATTAAAATATAG TCATGAGGAGACTTTCGAAAATAA ATTTCAGAACAAACAAACGCATTT TTTATTCCAAAATATCATATTGTTG CTTTTAGATAACTATTTACTGAGAA TGAATTTGAACATTGTTTCAAGAA ACCCTTCAAAACAAGCAAAGTAAA TTTGTGTTCTCATCTTCGTGCTCOT AGATACTTTGTTCATTTACTTCTTT CGTTAGTCATTTTTTGAAGTTCTAA CTAACTCAAGCATTCAATTTGTCC AGTACTCTTGATCCTGATGCCTAT CAGAATGAAAGTCAAGTGTCCCTG CTTTTAAAAGATATGGCTGTCAGG ATTCATGAGATAGTTGGTGTAAGG ATGCATCGTCTTACTGTTATTGAG TGGGAGGTAAAGCTCTGGTTGGG TTCTGATGGTGTTGCTGGTGGTTC TTGGAGGGTTGTGGTGACAAATG TTACTGGACGTACATGTAATGTCC ATGTAAGTGCGATTGATTCACTTT GTCTAAGACTTTACTACTATACTT GCATGGTTAGACATAATATTTCAT TTCCTTATGTAGGTAACGTTTTCTA GCATAGCTAATTGTTTGACTAGGA CTATATTAACTAATTGTAAAAATTG AACTTTTGCCATTAGAGCAGTTAA TTAATAGATATTGCTCTAGCCCGT AATTTTGCTTTCATTTGATTGTAAA ATACTCAGTAAGTTTTTGCTTCAG ATTTACCGAGAATTGGAGGACAG CAAATCACATGAAGTGGTCTATCA CTCTGCAGCTTCAGTCACAGGAC CTCTCCATGGTATGCCGTTGATTG CTAGATATCAGCCACTTAGTGTTA TTGATAAAAAACGATGGGTGGCAA GAAGGAGCAACACTACTTATTGCT ATGACTTTCCACTGGTATAGCTCC CAATTCCTGATTGATATACTCCCA GTTTTCTTGTTTTGATACTTCAATA CCTTACTAATTAATATGTGCAGGC GTTTGAGACAGCACTGAAGCAGT CATGGGCTTCTTATAGTGATACTA AAGCACCAGAAAGCAAAGCTCTTC TCCAAGTTCAAGAACTTATGTTTG TTGACAAAAAGGGATCATGGGGT ACTCCTGTTGAACCTGTATGCTGC CCACCTGGTCTCAGTGATATTGGC ATGGTTGCTTGGTCAATGGAAATG TACACACCAGAATTTCCCGAAGGA AGGAAGATTGTTGTTGTAGCCAAT GATTTGACTTTCAAAGCAGGCTCC TTTGGGCCTCGTGAAGATGCATTT TTCCATGCTGTAACCAATTATGCA TGTGATAAGAGGCTCCCTCTAATC TATTTGGCAGCAAATTCTGGCGCC AGGATTGGTGCTGCTGAAGAGGT CAAGTCTTGCTTTAAGGTTGGATG GTCTGATGAGTCGAGTCCAGAAC GTGGTTTTCAGTATGTGTATCTGA CACAGGAGGACTATAACCGTATTG GTTCATCTGTTATTGCACATGAAC TGAAGCTTGAAAGTGGTGAGATCA GATGGGTGATCGACACAATTGTTG GCAAAGATGATGACTTGGGTGTT GAGAACCTCACTGGCAGTGGTGC AATTGCCGGTGCTTATTCCAGGG CTTATAACGAGGTATTTACTCTTA CATATGTGACTGGACGTACTGTAG GAATCGGAGCCTATCTTGCTCGG CTTGGCATGAGGTGTATCCAGAG GCTAGACCAGCCTATAATCCTAAC AGGGTTTTCTACACTCAACAAGTT GCTTGGCCGTGAGGTGTACAGCT CACACATGCAACTAGGTGGCCCG AAGATCATGGCTACAAATGGTGTT GTTCATCTGACGGTATCAGATGAT CTTGAGGGCGTTTCTGCTATTCTT AAGTGGCTTAGTTACGTACCACCC TATGTCGGTGGGCCACTTCCAATA ATAAAATCCTTGGATCCCCCAGAA AGGCCAGTGGAGTATTTTCCTGAA AATTCATGTGATCCACGGGCCGC AATTTGCGGCATTGATGATGGCAA TGGCAAGTGGTTAGGTGGTATGTT TGATAAAGATAGTTTTACGGAGAC ATTAGAAGGTTGGGCAAAGACGG TGGTCACCGGAAGAGCAAAGTTG GGTGGAATTCCAGTAGGAGTTATA GCTGTCGAGACACAGACTGTGAT GCAAGTCATTCCTGCAGATCCTG GTCAGCTTGATTCCCATGAACGTG TTGTCCCACAAGCTGGTCAAGTTT GGTTCCCTGATTCTGCCACCAAAA CGGCACAAGCATTATTAGACTTCA ATCGTGAAGAATTGCCACTTTTCA TACTAGCCAACTGGAGAGGATTCT CAGGCGGACAGAGAGATCTCTTC GAAGGTATACTTCAGGCTGGTTCC ACAATCGTCGAAAACTTAAGGACA TATAAGCAGCCTGTATTTACCTAC ATCCCAATGGCCGGGGAGCTTCG TGGTGGTGCATGGGTTGTGGTGG ACAGCAAAATCAACCCGGATCACA TCGAGATGTATGCCGAAAGAACA GCAAGGGGCAACGTACTTGAGCC CGAAGGAATGATTGAGATTAAGTT CAGAACTAAAGAACTTCTCGAGTG CATGGGTAGACTTGATCCTGAGCT AATCAGTTTGAAAACAAAGCTTAG GGAGTTGAAGGCAGCTGGACCTT CCAGAGATGTGGACGTCCTCCAG AAAAGTGTAACGGCTAGAGAGAA GCAGTTATTGCCTGTATATACACA AATTGCTATAAAGTTTGCAGAGTT GCACGATACATCCTTGCGAATGG CTGCCAAAGGTGTGATCAAGAAA GTGGTAGACTGGGAGAACTCCCG TTCTTTCTTCTACAAAAGGTTAAAC AGGAGAGTTTCCGAGGATGTCCT TGCAAAAACTGTTAGAGATGCTGC TGGGGAGCAGTTGTCGTACAAGT CTGCTATTGAACTGCTTAAGCAGT GGTTTTCATCTTCCGACAATGTGG ACGTTGGAAAATGGGAGGAAGAC GATGCTTTCCTTGCCTGGAAAGAC AACCCTAAAAATTATGCCAAGTAT CTTGAAGAGCTACGAGTTCAGAA GATATTGCAGCAGCTCTCAGCTCT TGGTGAATCATCTTCGGATTTGCG AGTATTGCCTCAATGTCTTGCTAC AGTCCTTAGCAAGGTACAGTTTCT TTCATTGTGCATTCAATTTCTCOTTT TCAAAATATAGACATATAGTTAGAT TTTTACTTAGTTTTGCATCATTTITTC CCTGCAACATGGTAAACATTTCTC TATAAGTATTTTAATATCACTGCAA AATATTCAATAATGTTCCTGAACTT GTTCGGAGCGCCTTGATTAGTAG CTACACTAGCATTGCGATCTCACA GTAAAAGCTATCATTCTCTTTGAA ATAATTCTTTTAACTCTGGGTAGAT ATTTTTTCTTCTCTCAACTATATOT TGAAAATTTGTGCGATAAATTCCT AACATGATTATTGCTTGGCATTGA TGCAGATGGACTCGTCTAGTAGA GCTGATCTTGTCAAAGAAATCAAA GATATCCTTGGTTGATCAATTTGA CCTTATATATGGTGCACCGCAACA AATTAATGTGATGAACATCCCAGT AATGCCTTCTCAAGACGTTGAACG CAAGCCAGTATATTATATCTTITTITT TTCCCCGACAGAGTATCTACAGCT CCTACCAATTTCAGGATATTTAAT CATATTTTTCCTTGCGTAGTTCATA TAGAAACGACATTACTTCAGTTCA CCTGTAGATAAGTTGAATGTTGTC ATTCAAGCAGGATGTAGCAGTCCA CAACATTTGTATTTTITTATATITTCG AGATTCAGCTGTAAGGAATAATGG CTGTATTATTTTCTCTAGGAATGAA GAGTACACTTTATTGCCCAATAAA AGAAAGAAATGTCAGGGATTGTTT CAATGGAATTCCAAACTGATCTCA ACTACATTAGGCGTGGTTAAAAAA AAACTACACTACGTCTGTTGCCAA ATATAGAAAAGTATTTTTAGGAATA TTTAGGCTTTGTTTGGGAAACATA ATGACTTAATACAATAATTGTGTAA ACACAAGTAATTAATTACTATATTT GGATAACACTTTATAATACAAAGT CTCTCACTACAAATGTAATGTTTAT TATCTCATAGGAGCAAAAAAAAAA AAAAACTCTTAGGAGGTCGTGTGT AAATGTAATGTTTATTATCTCATAG GAGGTCGTATTCATTACACAGACA TATAATCCCATCATAAGATATCTCT CATGTTTACTAAAAATTTTCATTTT AAAATTTAAACATAAATGTTATTAC TAATAATATATACATTCTTTATTTAT TATTTTTATTATATTACACGTATTTT AGCCAATGTTGTAAGTCACTACAT TACAAATTTTGTAAATGATTTAATT ACGTTGCAAATCATTTTATCCTTC CCAAATAAGGCAGAATCACTTTGT CATTTCATGTGATTAAAAAAATAAG AGGTCAGAGATAATTACTTGGACT TGATATTATAGTAATTTTGCATGAT ATCTTACCCATTCTATGATATTTAA ACACTCATATTTGGACGTCATGGG ATCCTATGGAATAATGGAAATAAC TCAATGCTCATGAACTGGGCAAAA ACAATTAGCTCTTACCTTTTCTITT TTTCCCCTAACAAGATGATTCTAT GATGTAAATAACTTTACTGATTTTT TTTTATTTGCTTAACACACTCTCAA TCTATATGGTAATGGGCTAAAATC TTTTGCTCATGAGATTCAAATATTT CTCGCGAGATTTCGTTATTGCCAA ACAGGTCTGTTCTTTTGTAGTTAC TTAAATAATCATAAACTTTAGATAA GACCAACTTAATTTAAGTTAATCAA CATCATCAACTGAATATTAACTTTA CTAACACAATGTCCGTAATGGCAT GTTTTGCTCACTTGAAATAAAAAAT TAAAAAGAATATATAAGTAGCATT CGAAAATTAATACTACGTCCAATT AGAGTTAACATTATGACAACAATA CGACAATATCCAAATTACCATCTT TGCTCCTCTGTCTCCAAAAACTAA TGTTATTCATCTCGCTGCCCCCAA CCATTGAACCAATTGATATTCTAA CCTTAATCAATCAATTCTCCCACT CTCACTGACAACTGGACTCTGACC TCAGTTGGTGGCACCTCCGTCGT GGGCTTCTTCACTCCTTACAACTC TAATAACTCCTAGCTTAATTTTCAG TACAAAATCACAGTCCAAAATGTT GTATGGATAGCAAACAAAGTTAAA CCCATAATCCAAGGGCAGAATAAC AAACTCAAGCGAATCGGAGAAGA GCAGGACCGAGCACGAGATCTGG TCGACTGAGCTTGAGTGGGCCAA GCTTAAGCTTGCGATGGAGAAGA AGTGCGCCAGAGAAGAGGGGCAC ACCTGGATAAGGAAGGCGAGATA CACGAGCATGACCAAATCGAAAAT GAGCTGGAGGGGAAGGGAGGAG GAGAATAAGGGAGACATGAGAGG AGGGGAAGGATAACAAGAGGGA-
GA 64 Comme- |gD- |/3209 CAAGTAATTATTATATAATTTTCAC lina diffu- | NA- CCTATTCCATTTTATTTATTTITAAT sa Con- TTATTGACTATAAAAGTTACATAAT tig ACTGTACTTTATTTTTGTTTACTTT
TATTGAAGAAAAAACAGCCCTTCT CTCCCCTCACAAATAAATTAAAAA CAATTAATTTCCAATATTAGAGAAC CAAAAGTAATTCCCCTTAATGACA ATTTAAAAGAAAGAAATAAATACAA CCAACCTCTAAATCACACACATAT TCATATATTTATACAAATAAAATAA ATAGAGGGAGAGAGTAGTTGGCC ATCAGCCCCACCTAACAAAAACAA GTCTAGAGTCAAAATTGGGACAC GAAGATGTCATCTTCATTGTAAAA TCAAATGTTAATTAAACCCCAAAA ATAAAATGTAAGCACAAGATGTTT GAACAAGCACTTTGATTCCCAATT TTCACCTCAGGGGATCAAAAAGG CACCATCTTGACAATTATATATACA CACACTCTATACAACATTGTTGTG GTGGTAGTTGGCAGCTGTGGCTC TGAATTTCAATTCCTTTGTTTGCCC TTCAATTCCCTGTTGCTGTTGTTG GTGAGGAGAAAGGAAGCTGGCGT CACGTGGTGCTGCTGTCCATACC ATTTAAGGCCCTCGCCGTCTCCC CACCCCATTGGTGCCCTTTTCCCC CTTTTTAAATACTGCTTTITTTGGTG ATTTGGTGAATGGTGTGGTGAGG AGTCGTCAAAATCCCGCCTTTTTG CTGGGATTGTGCTCGTCTTAGCTC CCCTGAGCTGTTGGTTGTGTAAAG GTGCGATCTTGGTGCGTTTTGTTG GGTGAATTCGAGCTCTTTGTCGCT GTTTAGGGTTCAAGATTGCGCTTT TTTITITITTGCCCTTGTTAGTGTT GGTAGTTGTTAGTCCACCGGCTG ATTGAATTGTAGCTCTTTGGCACT GTTTGTGTGAGTGATCTGCTTTGC ATCAGGGGACTACAAATTTCATTT TAGTAGTGTTATGCTGGAATTTTG GTTCTGCTGATTGGGTTATTGCGC CTGTGTTATTTTGTCTTGTGCGTC TTAAATTCTGTCTGTAGTTTAGTGT TGTAACGAGTGCTTCTCGCTTCTA GACTTTGTTTGTATCTTCTGTGTCOT TGATTATTGTTACTATTATTATTITT ATTTTATTTTTGGTTAGTGAGTCAA CCTATGGGGTTAGTAATAAGACAT TGTTTCAGTTAGTTATGTGAATTG GTAACTCTTAATCTCGTTTAGAAG ATTGGTGAGTTAGTTTTTACCTGG TTCTGTACATTCGAATAGCTTTTAC TGTTGATTTGCTGCATTTTTACCAA ATTCTTTGTCGCTTTTTTGGTGTAA AGCAAGAATGAGAAAAATGATACT TGATTGAATTATGGGTTCCCAAAC CAAGTAATAATTTGGGAATTGCTT TCTGATAACTCTTTATTGGTGGAG CTTTGGTACTAGGATATATATGTA TATATATGATTATATCATATGGATA GCAACTGGGTAGTTGTTCAGTTAG AATCTTGGTCGTTAAAAGAAAAAA GAATGAATTGAATATTCATTITTATTT GAGCCTATGAGGATAATTTGTTAA CTGAAAATGGTTTTGTTCGAGTGG TAGGGATGTCTAAGGAGCCATGT AGTTCGTTTAGTTTGTTATTCTATT TTCATTCTTATAAAGAAATTTAATT TATCATGAAAGCATTGGGACCAGT TGTATAAATAGTTCTCCTTITTTACT GCAAATGGCAGTTACATAAAGAAT CTATTACAAGAATATGCTTATTAG GAGCTGGTTTATATTTTCAGTTTG CACTTTTTCTGTGTTTACTAAAGAA ACAAGTTATTCTTGTGCCTTTCTTA CCTGACGTCAGAGAATGATATTTT CTTGAAAGTCAAATGTTGCTTATT ATATATCCCGTCACTTTGCGTGTA TATTGATGACACTGATTAAATATCT ATGTAGAACGCCTGAAGCCCAGA AGGGAGCAGTTATGGCAGATGTC TGGCAAGATCATGGGATTTTAAAT GGGACAGTTCAAGTCAAACATGC AGCTACAACGTCTGAAGTTGATGA TTTCTGTTATGCACTTGGTGGAAA GAGACCTATTCGCAGCATATTGAT TGCTAATAATGGAATGGCTGCTGT CAAATTCATGCGTAGTATTAGAAC CTGGGCTTACGAAACATTTGGATC AGAAAAGGCAATTTTGTTGGTTGC GATGGCAACTCCAGAAGACTTGA GGATAAATGCCGAGCACATTAGAA TTGCTGATCAATTTGTAGAGGTTC CCGGTGGAACCAATAATAACAATT ATGCAAATGTTCAACTCATTGTGG AGGTCAGTTTTGCTTACTITTITTGG CTGACATTACTTTGATTGAGCATT TTGATTGTTTCTITTCITGTTTGTG CTGATTTTGACAACACACTTTGTG ACAGCTGGCCGAAATAACACGTG TTTCTGCAGTTTGGCCTGGATGG GGCCATGCATCCGAGAATCCCGA ACTTCCAGATGCCCTGAATGCAAA GGGAATAATCTTTCTCGGGCCTCC AGCTGCGCCAATGTCAGCACTAG GTGATAAAATTGGTTCTTCTCTAAT TGCTCAGGCAGCAGGTGTACCAA CTCTTCCGTGGAGTGGCTCACAT GTAATCTTACTTGCTAATTTGCAAA TACATTATTTCATATTTCTCATTCOT TTCACCAAAATTTACATGTGAAATT ATCTTTTAGGTCAAAATTTCAGCG GAAAGTTGTATGGACACAATACCC GAAGAGATATACAAGCAGGCTTGT GTTTATACAACAGAAGAAGCAGTG GCCAGCTGCCAGGTAGTTGGCTA TCCTGCCATGATAAAGGCATCTTG GGGCGGTGGTGGTAAAGGAATAA GAAAGGTATAGCATAAAAATAATC AGTAGTAGTTCTTTTATTCTCTCCA ACAATGCTTACAGAAAGGGTGGC AAATAGATTAGTGCAATGCCTGTG GCTATATATGCCAAAGAAGGTAGA GAAACGCTGAAACGGATATTGTTT CTTAATATTTTTGAGGTTATGATCT TATTTTGGTGTTCAGTCAACTCCT GAAGTCCAACAAATAATGATGTAG CCATATGTATTATCTAAACATGATT CATTTGTTTATTCATGGTTGTCATT ACAAATGGAATTACAGTACTCGTT ATGATATGCAAATTAAAAAAAAAA-
AAAA 65 Digitaria |cD- |1629 GTTGTTGCAAAATGAATGTGACAT sangui- NA- TTAAAGCTGGGTCCTTTGGTCCAA nalis Con- GAGAAGATGCGTTTTTTGATGCTG tig TTACCAATCTTGCTTGTGAGAGGA
AACTTCCTCTTATCTACCTGGCTG CAACTGCTGGTGCCAGACTTGGT GTAGCAGAGGAAATAAAGGCATG CTTCCATGTCGGCTGGTCTGATGA TGAGAGCCCTGAACGTGGTTTTCA CTACATCTACCTAACTGAACAAGA CTATTCACGTCTAAGCTCTTCAGT TATAGCTCACGAGCTGAAACTAGA AAATGGAGAAACCAGATGGGTGG TTGATACCATTGTTGGGAAAGAGG ATGGACTTGGTTGTGAGAATCTAC ATGGAAGTGGTGCGATTGCCAGC GCGTATTCTAAGGCATACAAAGAG ACCTTCACCCTGACATTTGTGACT GGAAGAGCTGTTGGCATTGGAGC TTACCTGGCTCGTTTAGGTATGAG GTGCATACAACGTCTTGATCAACC AATTATTTTGACTGGGTTTTCTGC ATTGAACAAGCTTCTGGGACGGG AGGTATACAGTTCTCATATGCAAT TGGGTGGCCCCAAAATCATGGCT ACAAATGGTGTTGTCCACCAGACC GTGTCAGATGATCTTGAAGGTGTT TCTGCTATCCTGAAATGGCTCAGT TACGTTCCTCCCTATGTTGGTGGT CCTCTTCCTATTATGAAACCCTTG GACCCACCAGAAAGACCTGTAAC ATACTTCCCTGAGAATGCATGTGA TGCTCATGCCGCTATATGCGGCAT TCAGGACGGTGAAGGCAAGTGGT TGGGTGGTATGTTTGACAAGGAAA GCTTCGTGGAAACATTGGAAGGC TGGGCAAAAACTGTTATCACCGG GAGAGCAAAACTTGGTGGAATAC CAGTTGGTGTCATAGCTGTGGAAA CCCAGACAGTGATGCAAGTCATC CCTGCTGATCCAGGGCAGCTTGA TTCCGCTGAGCGTGTAGTCCCTC AAGCAGGACAAGTGTGGTTCCCT GATTCTGCCACCAAAACGGCTCA GGCATTGATGGATTTCAACCGTGA GGAGCTTCCACTTTTCATCCTTGC AAATTGGAGAGGTTTCTCTGGTGG ACAAAGGGATTTGTTTGAAGGGAT ACTTCAGGCTGGTTCAACAATTGT TGAGAATCTGAGGACATACAAGCA GCCTGCTTTCGTATATATCCCAAT GGGTGGAGAGCTGCGGGGAGGA GCCTGGGTTEGTGEGTGGACAGCAA GATCAATCCGGACCACATTGAGAT GTATGCGGAGAGGACTGCGAAAG GCAATGTCCTTGAGCCAGAAGGA TTGGTGGAGATCAAATTCAGGCCA AAGGAACTGGAAGATTGCATGCTA AGGCTTGATCCAGAATTGATTGGC CTGAATGCTAGGCTGAAAGAGTT GAAGAAGCAAAATGCCAGCAACT CGGAAACGGAGACCATCCGTAAG AGTATGACAGTTCGGATGAAGCA GCTAATGCCTATATATACTCAGGT TGCCACACGGTTTGCTGAGTTGC ATGACACCTCCGCTAGAATGGCT GCAAAAGGCGTAATTGGTAAGGTT GTTGATTGGGAGGAGTCTCGGGC CTTCTCTACAGGAGATTGCGA-
AGGAG Digitaria |cD- |1468 CGTGGTGTAGATGACAGCCAAGG fes a O Jemosnosoreonomen nalis Con- CAAGGACAGCTTTGTGGAGACATT tig TGAGGGATGGGCAAAAACAGTGG
TTACTGGCAGAGCAAAGCTTGGA GGAATTCCTGTCGGTGTCATAGCT GTGGAGACACAAACCATGATGCA GCTTGTCCCTGCTGATCCAGGCC AGCTTGATTCCCATGAGCGATCTG TTCCTCGGGCTGGACAAGTGTGG TTCCCAGATTCTGCAACCAAGACA GCTCAGGCATTGTTGGATTTCAAC CGTGAAGGATTGCCTCTCTTCATC CTTGCCAACTGGAGAGGTTTCTCC GGTGGACAAAGAGATCTGTTTGAA GGAATTCTTCAAGCTGGGTCAACA ATTGTTGAGAATCTTAGGACATAC AATCAGCCTGCATTTGTCTACATT CCTATGGCTGGAGAGCTACGTGG AGGAGCATGGGTTGTGGTTGATA GCAAAATAAATCCAGACCGCATTG AGTGTTATGCTGAGAGGACTGCA AAAGGCAATGTCCTTGAACCTCAA GGGTTAATTGAAATCAAGTTCAGA TCAGAGGAACTCCAAGACTGTATG GGTAGGCTTGACCCAGAGTTGAT AAATCTGAAAGCAAAACTCCAAGG TGCAAAGCTTGGAAATGGAAGTCT ACCGGACATAGAATCCCTTCAGAA GAGTATAGAAGCTCGTACGAAACA GTTGTTGCCTTTATATACACAGAT TGCAATACGTTTTGCTGAATTGCA TGATACTTCCCTCAGAATGGCAGC TAAAGGTGTGATTAAGAAAGTTGT AGATTGGGAAGAATCACGTTCTTT CTTCTACAAAAGGCTACGGAGGA GGATCTCCGAAGATGTTCTTGCAA AAGAAGTAAGAAGAATAGCTGGT GACCACTTCACTCACCAATCAGCA GTTGAGCTGATCAAGGAATGGTA CATGGCTGCTCAACCAACAACAG GAAGCACTGAATGGGATGACGAT GATGCTTTTGTTGCCTGGAAGGA GAATCCTGAAAATTATAAGGGATA TATCCAGGAGCTAAGGGCCCAAA AGGTGTCCCAGTCGCTCTCCGAT CTCGCAAACTCCACTTCAGATCTA GAAGCATTCTCTCAGGGTCTTTCT GCACTATTAGATAAGATGGAACCC TCCCAGAGAGCCAATTTTGTTCAG GAAGTCAAGAAGGTCCTTGGTTAA TTGGATCATACCAACACAATGTGT ATGCAACATGTTTTTTGTTGAAGT ACATACATAGAAGGCCCTTGATGA GATCTGATCTGAATCTACCATTAT TTGTTAAAATTTGTTTGGTTGGAC GATCATGTGGTTGAGTAAGTGCTA AGTTGTCTCTGTAGTTCTGGGATG TATTACCAGCAGTTCGATTGTGTA ATTTTAGAGTGTATCATGCGGATA TTACATTCAGTTGAGTGGTTCATT AAATTTTGAACTCGAATAATTT
67 Digitaria |cD- 1194 GCAAGCGAACTTCTTGAACAAACT sangui- NA- AAACTAAGTGAACTCCGTGCAAGC nalis Con- ATCGCAAGAAGCCTTTCTGATCTG tig GGGATGCATAAGGGAGAAATGAC
TATTAAGGATAGCATGGAAGAGTT AGTCTCTGCCCCATTGCCTGTTGA AGATGCACTTATTTCCTTGTTTGAT TACAGTGATCCAACTGTTCAGCGG AAAGTGGTTGAAACATACATATCT CGATTATATCAGCCTCTTCTTGTG AAGGATAGCATCCAAATGAAACTT AAGGAATCTGGTGCCGTTGCTTTT TGGGAATTTTCTGATGAGCATGCT GACACTAAAAATGGACAAGAAGCT GTTCTTGGTCAAAAGAGATGGGG GGCCATGGTTGTCATCAAATCACT TGAATCTGCGCGAACAGCCATTGT AGATGCATTAAAGGATTCGGCATG GCAATCCAGCTCTGAGGGCAACA TGATGCACATTGCATTATTGAGTT CTGAAAATGAAAATAATATCAGCA GTGATGATCAAGCTCAACATAGGA TGGAAAAAATTACCAAGATATTCA AGGATAGTGGTGTTGTAAACGATC TCCGATCTGCTGGTTTGAAGGTTA TAAGTTGCATTGTTCAAAGAGATG AAGTACGCATGCCAATGCGCCAC ACATTCCTCTGGTCAGATGAAAAG
AGTTGTTATGAGGAAGAACAGATT CTCCGCCATGTGGAGCCTCCCCeT
CTCTGCGCTTCTTGAATTGGACAA GTTGAAAGTGAAAGGATACAATGA AATGAAGTATACTCCATCACGCGA CCGTCAATGGCATATCTACACACT AAGGAATACTGAAAACCCCAAAAT GTTGCATAGGGTATTTTTCCGAAC TATTGTCAGGCAACTGAATGCAGA CAACAAATTTGCATCAGCCCAAGT TAGCAACACTGAAGTTGGAGGTCT GGAGGAATCTTTGTCATCTACATC AAATAGCATTTTAAGATCGTTGATT ACTGCTATTGAAGAATTAGAGCTT CATGCGATTAGGACAGGTCATTCT CACATGTATTTATGCATATTGAAA GAACAAAAGCTTCTTGATCTCATC CCCTTTTCAGGGAGCACAATTGTC GATGTTGGCCAAGATGAAGCAAC TGCTTGTTCACTTCTAAAATCAAT GGCTCTGAAGATACATGAACTTGT
TGGTGCACAGATGCATCATCTT Digitaria |cD- |586 GAGAAGAAAAGGGGTATCATGGT sangui- NA- TGTAATCAAGTCTCTCCAGTTTCT nalis Con- AGCAACTGCAATTGATGCTGCACT tig GAAGGAGACCTCGCAATATAGAG
CAGGTGCTGTAAGTGTCTCGAAT GGTAACCATGTAAATTCAAATCAA AGCAATATGCTGCATATTGCTTITTG GTTGGTATCAGTAATCAGATGAGT ACACTCCAAGACAGTGGTGACGA GGATCAAGCACAGGAAAGGATCA ACAAACTTTCCAAAATTTTGAAGG ATAATACTATTACATCGCAGCTTA ATGGTGCTGGTGTTAAGGTCGTC AGCTGCATTATCCAAAGAGATGAA GGGCGTCCACCAATGCGACACTC CTTCCATTGGTCTGCTGACAAGCT TTATTATGAGGAGGATCCAATGCT CCGCCACGTGGAACCACCATTGT CTACATTCCTTGAGCTGGACAAAG TAAATTTGGAGGGTTACACTGAAG TAAAATACACCCCATCACGTGATC GTCAGTGGCATATTTACACACTTA TCAAGAACAAGAAAGATCAGAGAT TAAACGACCAGAG- GATGTTCCTTCGTACCATAGTCA-
GACAAC Digitaria |cD- |488 CAGCCTTTGAAATTACTGGATCAG sangui- NA- AAACGTCTTTTGGCCCGTAAAAGC nalis Con- AATACTACTTACTGCTATGACTTT tig GCACTGGCATTTGAAGCAGCCCT
TGAGAATATCTGGTCATCGAAACT CCCAGGTGTTAACAGGCCTGGTG CTAAGCTTGTAAATGTGACAGAGC TTGCGTTTGCTGACCCAAGAGGC TCATGGGGTACACCACTTGTGGA AATAAACCGTGAGCCGGGCCAGA ACAATGTGGGCATGGTGGCATGG ACCATGGACCTCTGCACACCCGA GTTTCCTCATGGAAGGACAATTTT GGTAGTTGCAAACGATGTCACGTT TAAAAACGGGTCTTTCGGCCCGAT TGAAGACGCGTTTTTCGAGGCGG TTACCGAACTTGCTTGTTCCAAGA AACTGCCACTCATCTATCTGGCAG CTAACTCAGGGGCCCGAATTGGG GCGGCTGAGGAGGTCA- GATCTTGCTTTAGA-
ATCGGGTGGTC 70 Digitaria |gD- |10084 | TITTCAGGTTTGTTTGTTTCGATTT sangui- NA- TCCGATTGTGTTTTTTGAGTCGCT nalis Con- GTTGCTTGATTTCTGCTGCTGTTA tig CTGCTGGTTGACTCTTCTAGTGTG
TTGATTGAGATTTGTTAGTTTGATT CGACTTCGATTTTGGAATCGGATT TTTGAACTTGGAGTTGTAAGTGTT TTGAAGCGTGTTTTTCGGCGTTTT AGTTGCGTTTTTCTTATGGATCCG ATTCTTTTATATGAATGCGGCGTT TGGCGCTGAGCAACATGAATTGG AATAAACTTGTGGTATTTTGCTCTT TTTCTATATATTAGTCTAATTCAAC TTCGATTATGGAATCTGATTTTTGA ATTTGGAGTATATGTAGTATATTTA AACATGTTTTTCGGTGTTATCATT GTGTATTTTTTATGGATCCTGTGC ATCGGAGATGCGTTTATATGAATA CTGTGTTTGGTGCTGAGCAACATA AATTGGATTATACTTGTCGAAAAT AATTCTCGTAATAAGGTTCAAGGT ATCTAGAAGTCTACCTGAAGTGAT ATAGTGGACCATGCGGATTTGATT CTTTGAGTTGTTTTTCTTCAAGTCA AAGATCCTGTTATATTTAATTATTT CTTTTGATTTATGAAATGAGTAATT AAGCAAGTGGTATGCTCAATTCGT TGAAAATATTATGTATTGAAAAGG ATTTGAAGGTTACGAACTGGATTT TCAACTCGAATGAGTTTITTITIITIGT GCAGAATGTTGGAGACACAGAGG AGGCAGCCGTTAGCAGTAGGGGT TACTCGTGGGAATGATTTCACCAA TGGTGTGCTTACGATGAGAAGCC CTGCTACAATATCAGAAGTAGATC AATTTTGCCGTGCTCTTGGAGGAA AGAGACCGATCCACAGTATATTAA TTGCAAACAATGGAATGGCAGCT GTCAAGTTTATACGAAGTGTTAGG ACATGGGCTTATGAAACTTTTGGC ACTGAAAAGGCTATCTTGTTGGTG GCCATGGCAACTCCAGAAGACAT GAGGATCAATGCAGAGCATATTAG AATAGCTGATCAGTTTGTGGAAGT TCCTGGGGGGACAAACAATAACA ATTATGCCAATGTGCAACTCATTG TTGAGGTGTGTAAGTTCATAACCT TTTAGCATATTGGATAGCTTATGTT GTGTTAGTCTAAAGTTCGATAATT CTAAGCATATAATGATATTAAATGT GTTTAAGGATTTCTCAGTAATAGG AATTTGTAAATCTTTTCTGTCAATG GGTTTTACAGAAATTCATAAATTAT AATGTAATCTAGAAGCTTTGAAAT TGTATTTTTGCACATCTCAGAAGA TTATGAAGTAATAGGCTGGTATAC AGTGAATTTCATTATTGCAAGATAT TGTTGTTATGTGCTCACTCAAGAG CATTCTTTTCAATTTGGCAATGTG AAAAGGTTCAGTTAGAAATATCAC TTGTTACCCTTGTTGTTTGCATAA CTAAGTTTGATTTTGTGTCCAGAT GGCAGAGGTCACCCATGTTGATG CAGTTTGGCCTGGTTGGGGACAT GCATCTGAAAACCCAGAGCTTCCA GATGCACTAACTGCAAAGGGAAT CGTATTTCTTGGGCCCCCAGCTG CGTCCATGGGAGCTTTGGGTGAT AAAATTGGATCCTCTTTGATTGCG CAAGCAGCAGATGTTCCTACTCTT CCATGGAGTGGCTCTCATGTAAGT AATGCTCTTCTCAAGCTGTTCOTIT CATTTTCTGTAGTCATTCCAATCTA AGATATCATGATCTTCCTTATAGG TGAAAATTCCTCCAGAAAGTTGTT TGATTACCATCCCCGATGACATAT ATAGAGAAGCATGTGTTCACACAA CAGAGGAAGCTATTGCAAGCTGC CAAGTTGTTGGTTACCCTGCTATG ATAAAGGCATCATGGGGCGGTGGÇ TGGTAAAGGCATAAGAAAGGTTTG GCTTCGATATAACAAATTTCCGAG TGTAGTGTTCAAGTCTGTAGTGTA CGATGGCTGAGTTTTGTTTTCITTG GATTATCTAGGTTCATAATGATGA TGAAGTTAGGGCATTGTTCAAGCA AGTCCAGGGTGAAGTTCCCGGTT CACCCATATTTATAATGAAGGTCG CTTCACAGGTTAGGATATTATCTA GCTTCTAATTTGATACAAGAGATT TTACTTTGTGATTCTTGACGCGTG AATCGAATTCTGATGATCTATTTG ATTTTCCTTATGTAGAGTCGACAT TTAGAAGTCCAATTGCTCTGCGAT CAATATGGAAATGTAGCAGCTTTG CATAGCCGTGATTGTAGTGTTCAA AGGCGGCATCAAAAGGCATGTTT ATTTCTCTCAAGTAATTTTGATTTT GTCTGCTTAGTGAAATTGACCATG AAAGTATAAGCTTAGTGTGAAGAG CCTGAGGCTCTGACCACATGCAT GTTGAGAATGAGCCAGTGACTTTT AATCAGTGGCTCAACCATTAATTT CTCCCCTTCCAAATTTCAACTGTT TGTACATCTATCTAGTATCTACTAC ATGGGTTATGCATTTCAAAAAAGG CCTAACTTGTGTTGAGATGTGAAA CAGATAATTGAGGAGGGTCCAATT ACCGTTGCACCATTGGTGACTGTA AAAAAACTAGAGCAGGCAGCTCG AAGGTTAGCGAAATCTGTGAATTA TGTGGGCGCTGCTACTGTTGAGT ATTTGTACAGTATGGAAACTGGCG AGTACTATTTTCTAGAGCTCAACC CTCGGTTACAGGTATAAATGAATA TAGTTTGTAGGGATGTGAAGTTGT TATGCTCTATAGTAGTAATGATAT CTAAAATGCTTAAATTTTATGTTGC TCAATTGATGACAATTGGATAAAC CGTATTCACTTGGGAAAAACCATC CTGAATATAGTTCGTACCTCATTC ACCTTGCGTACTACTGATATTGAT CCTATGAATCTGTTTTTTAAAATAT CTTTGTTTCTGTAATAAATTGTTCT TTGACTTTTCTAATGATCTTTAATC TACATCCTAATCTGGATGTAGGTG GAGCATCCTGTCACAGAGTGGAT TGCTGAAATAAATTTGCCTGCTGC CCAAGTAGCTGTTGGGATGGGAA TTCCTCTGTGGCAAATTCCTGGTA TGACCGCAAAAGTTGGAAATTCGC ATTCTCTTGCTCATTAGACATGTTT CTTTGACATTCTGTTCATTTITATT CAGAGATTAGGCGATTTTATGGAA TGGAACATGGTGGAGGATATGAT GCTTGGAGGAAAACTTCAGTGGC TGCTACGCCTTTTGATTTTGACAA GGTAGACTCTACAAAGCCAAAAG GTCATTGTGTAGCTGTACGTGTGA CAAGTGAGGATCCAGATGACGGT TTCAAGCCTACTAGTGGAAAAGTA CTGGTAAGGTTTTCAGGTTGACTA TTCTAATTTGAATTTCCTTCTATTC CAAAATTCCTTATCCTGTAATGAA CTTGTACTTTTATTGTCTTGCACA GGAGCTGAGTTTTAAAAGCAAGC CAAATGTGTGGGCTTATTTCTCTG TGAAGGTGACTTTTTGCTGCTCTC TTTCTTTGGAACATGTTTATGTTGA CACAATTGGTTTCTGACTTAATAA CTTCATTCTGATTTGTAGTCTGGT GGAGGCATTCATGAATTCTCAGAT TCACAATTTGGTAAGTAATAATTG CTAAATAATCACACTTCATGGATA ATAATGAAAAGAAGTTTGTGAGAT GAGTTATCCAATCTGCTGCAAATT AATGGTTCTTTTITATCTTCTTGTG ACATTTTTTTTAACAAAAGCTACAG TCTGCTTTTCAGTTTAGTCTTTTCC GTTTGTTACATTTGCTATCGAAAG CACTCATGATTGTCGTAATCTTTC CTTAGGACATGTTTTTGCATTTGG GGAGTCCAGAGCTTTGGCAATAG CTAATATGGTTCTTGGGCTGAAGG AAATACAGATAAGAGGAGAAATCC GCACCAATGTTGACTACTCTGTTG ACCTTTTACATGTAAACTATCTTAG CTGTTGATGTTCCCTTTATACATC ATGTAAACTTTCACGAGGAACATG AACACGAGTTGACATGCTATGCAG GCTTCAGATTATAGGGAAAATAAA ATTCACACAGGTTGGTTGGACAGT AGAATAGCTATGAGGGTTAGAGC AGAAAGACCTCCTTGGTACCTCTC TGTTGTTGGAGGGGCACTATATGT AAGTTGTCACGATTTCACATGAGA GGATGACTGTATACTTTTGGAATG CTTTATTATGTCTTTCAGAACTTGC CACTTAAGTGTTCAATTTTTTGITT GCACCAGAAAGCATCTGCTAGCA GCGCAGCTATGGTTTCTGATTATG TTGGTTACCTTGAAAAGGGCCAAA TCCCTCCCAAGGTACATCAAAAGT ATATTTGTACAATTGTATATGTTTC TTATTCAGCCGATTATGTTGATGT TGATGTTGATGTTAGTTGATCTTG TTTTCAGCACATATCACTTGTGAA CTCTCAAGTTTCATTGAACATCGA AGGAAGCAAATATACGGTATGGTA CCTTTCATATTAGTATCTTAAATGA ATAAATTTTAGTTTGGTGATGGAT GCCATTTACGTTTGTAAAATCATT GCTAGATTGACATGGTTAGAGGG GGGCCAGGGAGCTATAGATTGAG GATGAATGGATCGGAGATAGAGG CAGAAATTCATACACTGCGTGATG GAGGTTTATTGATGCAGGCAAGTT GACTCATTAACCATGGCTGTTGTA AACTAATAATTTTCGTCCTTTITTAT CATTTAATATTTGCTTTAGTCGACC CTCCATGCTTTGGAGACCATAACA GACTCTATTCTGTTTCTTCACAGTT AGACGGAAACAGTCATGTAATATA TGCTGAAGAAGAAGCAGCCGGAA CTCGCCTTCTAATTGACGGGAGG ACTTGCTTGCTACAGAATGATCAT GATCCGTCAAAGTTAGTGGCAGA GACACCATGCAAACTTCTGAGATA TTTGGTTTCAGATGGTAGTCATAT TGAAGCTGATGCTCCATATGCAGA GGTTGAAGTTATGAAGATGTGCAT GCCTCTTCTTTCACCTGCTTCTGG AGTTGTCCATTTTAAAATGTCTGA AGGTCAAGCAATGCAGGTGTGTTT GATTTCACAAACACGTGCTTTTGG GCTTGATAAGTACTTTTTAGTTTITTA TATGAATAGTCAGTTTTGATGTGA ATCTAAGAAGTTTTCATGTAGGCT GGGGAGCTCATTGCAAGGCTTGA TCTTGATGATCCTTCTGCTGTAAG AAAGGCAGAGCCTTTTCATGGGA GATTCCCGCTACTTGGCTCTCCGA CTGCTATTTCTGGTAAAGTTCATC AGAGATGTGCTGCAAGTTTGAATG CAGCCCGTATGATTCTTGCTGGCT ATGATCATAATATTGATGAAGTAA GTTGCAAGCTGGCTAGTTTCAACA TGAACTTAATTGATGAATTAATTGT TCATTCTATATTTTGTTGATTGTGT AATTTCATAACAAAATAATGAACTA TGCATTTGGTTTATTATACTGACAA TTATTTGTTGAAATCTGATGTAATA TCTCAATGACATCTATAGGTAGTG CAAAACTTGCTCAATTGCCTTGAC AGTCCTGAACTCCCTTTCCTTCAG TGGCAAGAGTGCTTGTCTGTTCTA GCAACTCGCCTTCCCAAGGATCTT AGAAGCGAGGTGAATAATTTITCT GTAATTTTTTCATGACCACATAGT CTTCTTGCTCACAATTTGATATTG GCAATTTGTATAGTTGGAATCAAA ATACACAGAGTTTGAAGGAATTTC AAGCTCCCAGAACATTGACTTCCC TGCCAAACTGTTAAGGGGTGTCCT CGAGGTGGGTTCCTTATTGCATG GCTCTCTTGGAATTTCTCATTATOT GTTTTTTTTGCTGTTTAATGAGATG TGTATGCTTTTCCTCCAGGCACAC CTGAAATCCTGTCCTGAGAAAGAA AAAGGAGCCCTGGAAAGGCTTGT TGAACCTTTGATGAGTCTTGTAAA GTCTTATGAGGGAGGACGTGAGA GTCATGCTCGAGTGATCGTCCAAT CACTTTTTGAAGAGTATTTATCTGT AGAAGAATTATTTAGTGACAACAT CCAGGTTAGCTTCTTCCTATCAAA CATAATATGGAATTATTTTGGATTC TGAAAGTCTTCCCTCTTTGGCATC TTTTAGAAAATTAAGCATAATACTA GGTACTATATCCATTATTCTTTATA ATCATGAAATTTAATTTTTACAGAA GAAAAGTGGAATTTCTATATATATT TAAACCAAGCTGGCAAGCTTTGAA TTCAATCCTGTTGTTTATTGTTTTA TCCAACATGCCAAAAATATTAGGA ACTTCATGTGACTACTTGTATCATT CTTATTCTGTAATTACAGTAAAGTA ACTTGTCATATCCTAATGTTATAAC TCGTAACATTCTTCTTTAGGCTGA TGTGATTGAACGTCTCAGACTTCA ATATAAGAAAGACCTTTTGAAGAT AGTGGACATTGTCCTTTCTCATCA GGTATCTGATTTTCGGTTTTAATTT TTATCTCGGGTTTTCTAAAATAGA ATTCTGAGTTTGTGGAAATAACTA CCGTATTTGTTGGTTTATAGGGTG TTAAGAGTAAAAATAAGCTGATAC TACGGCTCATGGAACAACTTGTTT ACCCCAACCCTGCTGCATATAGG GATAAACTCATTCGGTTCTCTCAG CTTAACCACACCAGCTATTCCGAG GTTGGCAGCTATACTTGGTCCATC TGTAATTTCATAAAGTTGTTGCTCT GTTTCCTTTTGTTCACAAGTTCATT TTTGAGAGTTTTCCATAGGATGGT GACTGACAGGAAGAGGATTCTAAT GTTTTCTCTTGGAGGATTTITTCOT GTATTTTCATTTCTTGTCGGTCATT GATTAATTCCGTTTCTGGTATCAG TATCATCAAAATGTTGTCTTITTCT GTATACTGATGCTGAATTATGTGA ACAGTTGGCATTGAAGGCAAGTC AACTCCTAGAACAAACCAAACTGA GTGAACTCCGTTCCACTATTGCTA GAAGCCTTTCGGAATTGGAGATGT TTACCGAGGATGGTGAAAATATGG ATACTCCCAAAAGGAAAAGTGCCA TTAATGAACGTATGGAGGATCTTG TGAGTGCTCCTTTGGCTGTTGAAG ATGCTTTAGTGGGTCTTTTCGAGC ACAGTGATCACACCCTTCAAAGGC GAGTGGTGGAAACTTATGTTCGTA GGCTATATCAGGTACTGTGTTGTA GAAACTTAAAACTTITTATCTGGTG ATCAAACACTAGACGAAACTTGAT CTTGATCAACTGTTTGTCTACCGC ACCAGCCCTATCTGGTCAAAGGTA GTGTCAGGATGCAGTGGCATAGA TTTGGTCTTATTGCTACATGGGAA TTCTTGGGAGAGCATATCGGGAG AAAGAATGGATCTGAAGGTCAAAT GTCAGATGAACCAGAGGCTAAAA AACAGTCTAATAAGAGATGGGGA GCAATGGTTATCATCAGATCTCTG CAGTTTTTGCCTTCAGTTATTGGT GCTGCATTAAGGGAAACAAATCAA AGCCTTAATGAGTCCATTCCAAGT GGATTAGTAAAATCAGCGAGCTTT GGTAATATGATGCACATAGCATTG GTAGGCATCAATAATCAGATGAGC TTACTACAGGATAGGTAACTTCCT TCGGTACTATAATATAAGCGTTTA TTTTAATCATAAAAATTAGTAGCAT TTTACATTCTATTATTCATTGTAAG ATCTCAAGTCTTCTTAATCATTTCOT GCATTTGAAACCTTGATAGATCTG GATAGATTCCTTATTTTTGTTTAAA ATTTATGATAGAGTTACCTGGTCT CGAACCCTTAAAACATGCACATAT ATTGGCTTGCCAAACATAAGTTAT TTTGCGTTGTCAATTTCGATTATTG ACGGTCAGCTTGTTAATGCTCCTA ACTGGCACCATCTATGACATTTTG CAGTGGTGATGAGGATCAGGCAC AAGAGAGAATTAACAAGTTAGCCA AAATTCTCAAAGAACAGGAACTAG GTTCCAGTTTGAGCTTGTCAGGC GTTGGAGTTATTAGCTGTATCATA CAGAGGGATGAAGGGAGAGCCCC TATGAGGCACTCCTTTCACTGGTC AGAGGAAAAGCTTTATTATGAGGA AGAACCTCTATTGCGACATTTGGA ACCTCCACTATCCATCTACCTTGA ACTGGTTTGTCACCTATCGCAGTG TTTCAATACATTTTTTTGGCAGAAA CCTTTATTGAGCCCCTGAACTTAC CAGTTTTATTCTCAAGTTATTATTT GACTACATTAAATACTTAATTACTA TTGATTCCACATTATGACCTTGCA ATATAATTACAAGTGTTACGTTTTA TTGATAAAATTATAACTGTTGCTAT TTTGTTTTACATATATCAAGGACTG CACTATAGTAAAAAAATGAGGACT CGATAGGATTGGAAAGTTCAGGG GCTTACTAATTGTTTGAGCGGAAA AAAATATATATAAATGTGAAATTGG ATAATTCTATATCATTCATCTGAAG CTTATTATGGCCTTTTTTTGATCCA GGACAAACTTAAAGGCTATGACAA TAGACAATATACTCAGTCAAGGGA CAGACAATGGCACATGTACACTGT TGTAGACAAACCAGTTCCAATCCA GAGGATGTTTCTAAGAACCCTTGT GAGACAGCCCACAAGTACTTCATA TCAAGGTCTTGGCGCCGAAGCAC CCAATGTGCAGTGGGCCATGTCC TTTACGTCAAAGAGCATTTTGAGG TCCTTAGTAGCTGCAATGGAGGAA CTGGAGCTTCACGTGCACACTGT CAAATCTGACCATGCTCATATGTA CCTCTGCATATTGAGGGAGCAAC GGATAGAAGATCTTGTTCCATACA CGAAGTAATTATATCAATCTTTATG ATTTATTGTGTACTTGGCACCATA ACTTTATGTGTACTCACTATGAGA CTCCATCTCCAGGAAAACCGATGT AGATGCCAACCAAGAAGAAGCTG CGGTAGCAAGAATCTTGGAAGAA CTAGCGAGGAAGATACATGCGTC GGTTGGAGTCAGAATGCATAGGT TAAATGTTTGCGAGTGGGAAGTGA AGCTATGGATGACATCATCTGGAC AGGCAAATGGTGCTTGGAGAGTT GTCACAACAAATGTGACTGGGCAT ACCTGTGCTGTGCATGTAAGTATC TGCGCATCTTATTTCAAGAAAATG TCTTTCCCTTCCATGCATTCCTTAT TAGTCGACTTAGTAATGGGGAATG TCGAGAAGTGTTGGATGGTTACCA ATGTGAGTACCATCACTGTTTAGA TTAAAATTGACCATTGCTTTAGCA ATACAATAATGAATCTAATTGTGG CATGGGAGGCTTTTCTATGTGTGA TCCATGGAAAAACTTGTATATAGT TCCTTAGTAGGTTTGAGTTGTTTITT CATTTTTCTTTTATCACATTGTAAT TGTATTGGTGATTGATACGAAAAT TAGATATATCGGGAACTTGGGGA CGAGAGCAAACATGAAGTGGTGT ACCATTCAATCTCTCCAAGAGGCC CACTGCATAGCATGCCAGTGAAT GCTGTTTATCAGCCCTTGGGAGTT CTCGATCGAAAACGTTTGTTGGCA AGGAAGAGCAACACCACTTACTG CTATGATTTTCCACTGGTTAGTATT TCTATAATCATTAATCAAACATCAG TTTTTTTATTGGGGATAATTAAAAT CAAATAATTTTTCCTGGCCTCATC CTTTTCAGGCGTTCGAGACAGCC ATCGAACAATTATGGGAATCTCAA TCACCAGGGACTGAAAGAAACAA AGAAAAAGTCCTAAAAGTCTCGGA GCTTGTTTTTGCCGATCAGAAAGG TACCTGGGGAACTCCACTTGTTCA TGCAGAACGGCCAGCTGGGCTTA ACGACGTGGGCATGGTAGCATGG TGCATGGAAATGTTCACCCCGGA ATGCCCTTCCGGAAGGAAAATCTT GATAGTAGCGAACGACGT-
GACCTTCAAAGCCGGGTCTTTC 71 Digitaria |gD- |2626 AATCAACTTTATGCTCAAGCGAAA sangui- NA- GAGCTTATATTTGCTGATTCAGTT nalis Con- GGAGCATGGGGCACTCCAGTGGT tig TTTAGTTGAACGCCCTCCAGGCAA
CAATGATATTGGCATTGTTGCTTG GAACATGAAGCTGTCCACACCAG AATTTCCTAATGGCCGCGATATTA TAGTTGTTGCAAATGATGTGACAT TTAAAGCTGGGTCCTTTGGTCCAA GAGAAGATGCGTTTTTTGATGCTG TTACCAATCTTGCTTGTGAGAGGA AACTTCCTCTTATCTACCTAGCOTG CAACTGCTGGTGCCAGGCTTGGT GTAGCAGAGGAAATAAAGGCATG CTTCCATGTCGGCTGGTCTGATGA TGAGAGCCCTGAACGTGGTTTTCA CTACATCTACCTAACTGAACAAGA CTATTCACGTCTAAGCTCTTCAGT TATAGCTCACGAGCTGAAACTAGA AAATGGAGAAACCAGATGGGTGG TTGATACCATTGTTGGGAAAGAGG ATGGGCTTGGTTGTGAGAATCTAC ATGGAAGTGGTGCAATTGCCAGT GCGTATTCTAAGGCATATAAAGAG ACCTTCACCCTGACATTTGTGACT GGAAGAGCTGTTGGCATTGGGGC TTACCTGGCTCGTTTAGGTATGAG GTGCATACAACGTCTTGATCAACC AATTATTTTGACTGGGTTTTCTGC ATTGAACAAGCTTCTAGGACGGG AGGTATACAGTTCTCATATGCAAT TGGGTGGCCCCAAAATCATGGCT ACAAATGGTGTTGTCCACCAGACC GTGTCAGATGATCTTGAAGGTATT TCTGCTATCCTAAAATGGCTCAGC TATGTTCCTCCCTATGTTGGTGGT CCTCTTCCTATTATGAAACCCCTG GACCCACCAGAAAGACCTGTAAC ATACTTCCCTGAGAATGCTTGTGA TGCTCGTGCCGCCATATGTGGTG TTCAGGACGGTGAAGGCAAGTGG TTGGGTGGTATGTTTGACAAGGAA AGCTTCGTGGAAACATTGGAAGG CTGGGCAAAAACTGTTATCACCG GGAGAGCAAAACTTGGTGGAATA CCAGTTGGTGTCATAGCTGTGGA AACCCAGACAGTGATGCAAGTCAT CCCTGCTGATCCAGGGCAGCTTG ATTCCGCTGAGCGTGTAGTCCET CAAGCAGGACAGGTGTGGTTCCC TGATTCTGCCACCAAAACGGCTCA GGCATTGCTGGATTTCAACCGTGA GGAGCTTCCACTTTTCATCCTTGC AAATTGGAGAGGTTTCTCTGGTEG GCAAAGGGATTTGTTTGAAGGGAT ACTTCAGGCTGGTTCAACAATTGT TGAGAATCTGAGGACATACAAGCA GCCTGCTTTCGTATATATCCCAAT GGGTGGAGAGCTGCGGGGAGGEGÇ GCCTGGGTTGTGGTGGACAGCAA GATCAATCCGGACCACATTGAGAT GTATGCCGAGAGGACTGCGAAAG GCAATGTCCTTGAGCCAGAAGGA TTGGTGGAGATCAAATTCAGGCCA AAGGAACTGGAAGATTGCATGAAT CGACTCGACCCAAAGCTGATATCT TTAAAAACCAAACTAACCGAAGCG AAGAATAGTGGGACCTACGGGAT GGTCGATTCCGTACAACAGCTGAT AAAATCCCGGGAAAAGCAACTTCT GCCGCTTTACACGCAAATCGCCA CACGATTCGCCGAGCTTCACGAC TCGGCTTTACGAATGGCGGCAAA GGGGGTGATTCGAGAAGTTGTCG ACTGGGGGATTTCACGATCTTACT TCTACAAAAGGTTAAGAAGGAGAA TCGCCGAGGCTTCGTTGGTGAAC ACCGTGAAAGATGCAGCGGGTGA TAAGCTCCAGCATAAGTCGGCTAT GGAGTTGGTCAAAAACTGGTTTCT GGACTCGAAAGGCGATTGGGAAA ACGATGAAGCTTTCTATGCTTGGA AGGATAATCCCGCGAATTACGAG GAAAAGCTACAGGAGTTACGGGT CCAGAAGGTGTTGCTTCAGTTAAC TAACATTGGCGAGTCTTTGTCGGA TTTGAAAGCTTTACCTCAAGGTCT TGCTGCCCTTCTAAATAAGGTAAT TTTTTGGGTTTTTTCTTCCAGGAAT ATTGTTTATTTAGACGATCGAGTC GGATGTTATGTAATACTTTATGTTT GATGTAGGTGGAGCCATCGAGCC GAGGGGCGTTGATCGATGAGCTT CGGAAGGTGCTTAATTGATTITTCG GTAAGTGTTTCTCGGCTACTAAAT ATGTTTTACTTTGGCTTCAGTCTCT GGGTAGTTTGAATCAATAGAAAAT GCCAATGTGAAAATACCCAGTAAT ATATTTGATAAGTGTAAATGTAACT ATTATTATATTTAAGTGAATAGGG GGAATTAGTTCATATGATTATTGTT GTTATAAACAAATCAGAGATAGAG AGAGCTATATTTATTATTATATTTG CGAATTAAAGTTATTAGGAGTAGT ATAATTTGGCGGTTGTTGCATTTT ACGTGTAATGATCTGAATGTTGTT TGTTCGTGATTATTGAATAAAAGG GCATCAAATGCCATAATTTATCTTT CTTTGTTAACAAGATTTTAATTAGT TTTTTTTAATTATTAGTATGTTTTG-
TATAATTTATATT 72 oem [oo 2957 | Totereretereroreteaaetar sangui- NA- GTTCTTCGCTTGCTTCTCAGCTCT nalis Con- GCACCGCTCGGGCGATCGAATTT tig CGCATTGCTCCGTGTGCCGCCGG
CCGCTCEGAGGCTGTCCGCGTCCA AATCCAACTCCAAAACGCGACTTC GCGCGGCGCCGACGCTACTAAAT CGCCGCTTGTACTTCTCAGCCGC GCCGGGCAACTTGCTTCGGCGTT CCGTCGAGCAGGTTGTGCGCGCG CCAAGTGTGATTGGGGAAATAGA GATCCTGCCTGCTGCTGGCAACC GGAATTTCGTCAATCAAAGGCAG GGGGTTTCCTTTTCAGTTTGGTTA GGGAGCTTGTTGTTITTGITITGITTG GGGTGCCGGGGEGTTEGGTCCCCTCT GTTTTGGATTGGATTGTAGTGGCC TTTCGGGTTTCCACTTTGGACTCG CCTCTAGTGCGGACCTTTCTGTGA TCGCATAACACATACTACGGTCAA TATATTAGTCACCTTTGCCTAGGT ATAATCAAAACCTGTGTCCTGACA CTTCTTATTCTGCTGGCTGCTTGT ACTCTAATTCAATACAATCAGCTG CTGCCTATGGATGAATCTGGTTAA ATAGCCACTTCTCTGTTATCAACT CTATATCATCTCAGCACACTATTT CATATACTACTAGTTGCCTGTCCG AAAGTATCGTGCTTGCGATTTGTT TCTTTTGCCTGTTCGATAGTCATG CAGTTTCCCCGTCACAATTGATGT ACTAACAATCTGTTTCTTTTGCACT GACCAGGAAGTTTGAACTTCAGA GGGTGAGATAATGGTTGAGCCTG ACCAGATGAACGGCATACTGAAT GGGATGCCTAATTTGAGGCACCC GTCCTCTCCATCAAAGGTCGATGA ATTCTGTAAAGCACTTGGTGGCGA CTCGCCAATACACAGTGTGCTAGT TGCCAACAATGGGATGGCCGCGG TCAAGTTCATGCGCAGCATCCGC ACATGGGCCTTGGAGACCTTTGG GACAGAGAAGGCCATTCTCTTGG TTGCTATGGCCACTCCGGAGGAC TTGAGGATAAACGCCGAGCACAT AAGAATTGCTGACCAATTCATAGA AGTTCCTGGAGGAACAAATAATAA CAACTATGCGAATGTACAGCTCAT TGTCGAGGTTAGCACAACTCATCA TCCTGGAAGTGACTAACTTGTGTT TAGTTTACATATGTTTTCACTCTGG ACAATTCAGTAATTAACACTGAATT CACATTTCACAGATAGCAGAGAGA ACTCGTGTCTCTGCAGTTTGGCCT GGCTGGGGTCATGCATCTGAGAA TCCAGAGCTTCCGGATGCTCTAAA CGAAAAAGGAATAATTTTCCTTGG GCCACCATCAGCTGCAATGTCTG CACTCGGTGATAAGATTGGTTCTT CTCTTATTGCACAAGCAGCAGGA GTTCCAACTCTTCCATGGAGTGGA TCACATGTATGCCTTCGCCTATTT CTGTGTGCCTTTGCTTCTAACTTT TATCTGCTAGTTTAATATTCACTTA ACATTGAACCAAACTCACTGCAGG TGAAAGTTCCACCAGAAAGCTGC CACTCGATTCCTGAGGAGATATAT AAGGATGCTTGTGTTTCCACTACA GAGGAAGCAGTGGCTAGTTGCCA GGTGGTCGGGTATCCTGCCATGA TCAAGGCATCATGGGGTGGCGGT GGTAAAGGAATAAGGAAGGTTGG TTTTCTTTTITCTATTTGAATCTGAG AAAAAAGAAGGGAAATGTCCAGTA TTCAGAAAACATGATCTGAAAGTT TCAAGGAAAAAGTTAGAGTAAATT AACACTAATTTTGATATCATTTGCA TGGATTCATAGGTACACAATGATG ATGAGGTGAGGGCACTGTTCAAG CAAGTTCAAGGAGAAGTCCCTGG CTCACCTATTTTTATTATGAAAGTG GCATCTCAGGTGAGAACTGATTCA ACAAATTTTGGCTATTTAATGGTTT GCTTTGGCGCCCACCTTTGTTCOTT TGTATCCTGAGCTCTTCTATGTGG TTGCATTTGTTTCTGAAAGCTTTTG TTTGTTCTTTCTTTGTAGAGCCGA CATCTGGAGGTTCAGTTGCTCTGT GACAAACATGGCAATGTGGCTGC ACTGCACAGTCGAGATTGTAGTGT TCAAAGAAGGCACCAAAAGGTTA GCTCGTAGAATTTTTTCTAAGCOTTT GATTTACATTGTGATTTCTTGTAAT TTGTCCCATACTTGGATTGTGTAG TGTGCTGTATAGTAGTTTTATATAT TTCTTGAATAAAGTTTAGGTGACC TAGTGCAAGACGAAAAAAAATCCA TATTGCATTTTTGTGAAGAAAATTT
TCTCACATTTACCTCTGCA 73 Digitaria |/gD- |/2088 TTCAGTTGGATGGAAATAGCCATG sangui- NA- TAATTTATGCGGAAGAAGAAGCTG nalis Con- GTGGTACACGACTTCAGATTGATG tig GAAAGACATGCTTGTTACAGGTGC
ATATGCTCTTTTCCCTTTATTATOT TCTTGGTGTCTGATTGGGAGTCTT CTGCCAGATTTGCCTTTTCCGTTT ATTACAACAATTTGTCTGTCATCCT TAACTTCAGAAAATCCTATTGTTTG CTTTCTTAGCATACTTGATTTCAGT GAAATTTGACTACAATACCTGAAT TAAAAAAAAACTGTAATCGTGTGA TTAAAAATCAAGAAGTAGCCTTTTT AGGATTGTAATATTTTGGTATTGC TACACTATGCCAGAAGTAGGTCAC AAGTGTGTGTTCTTGCAGAATGAT TATGATCCATCAAAGTTAGTAGCT GAGACACCCTGCAAGCTTCTTCG GTTCTTAGTTGCTGATGGTGCTCA TGTTGATGCCGATGTACCATATGC GGAAGTTGAGGTTATGAAGATGT GCATGCCTCTCTTGTCCCCOTGCTT CTGGTGTCATACATGTTATGATGT CTGAGGGCCAGGCATTGCAGGTT ATTTTTGTACATCCCTCCTTGCATT GTGCTTGCATCACATAACTGCATG TAACATTTTTAGACTTATATTTTGT TCTAGGCTGGTGATCTTATAGCGA GGCTGGATCTTGATGACCCTTCTG CTGTGAAAAGAGCTGAACCATTTG ATGGAATATTTCCACAAATGGGTC TTCCTGTTGCTGCCTCTAGTCAAG TACACAAAAGATATGCTTCAAGTT TGAATGCTGCTCGAATGGTCCTTG CAGGATATGAGCATAATATCAACG AAGTAAATATTCCATCTTATTATGA TTATACTCTATTTAGTTTTTTITTTAA TCTTTTGTTTCCTTTACTITTGATTT GTGTACTCCATCCCAAAACAGTGT GATTCTAGTGTTGTCCTAAGTATC ATTAGATTCATCATGAAATATATTT TGGGACTGTTTTGAGGGTTCACAC GGGTTCAATGTTTITTITITITTGGITT CTGCTGACTTTTCGTCCAAACTTG TATAATCTATGGAAAATTGTAATG GTAAGTACGTTCTGATCATGCTCA CATAGTCACACTAGTGTAACTTTA TATTCTAGTTTGATAATTTTGAGTC GCACTTATTTAATTGAAGTTATTGC ATTTTGTTTTCTATCACATTGTCCT TAGCATTTATTTATCACATATTGAT TGATTCGCTCGAAACTCTTITTITIT TCCAGGTTGTGCAAGATATGATAT GCTGTCTGGACAATCCGGAGCTT CCTTTCCTACAGTGGGATGAACTT ATGTCTGTTCTAGCAACTAGACTT CCAAGAAACCTTAAGAGTGAGGTA TAAGACAATTACCAAAATGTAGCC AATCTGGGTTAAATGAAAGACGAT TCATTTTACTGTGTATATTATCTTA ATTTTACATATTGGCTTATGTTGAT GACAGAAAAGTTTGGTATCACCAG AGTAAAACCGTGATATTTTGTAGC ACTGGTTTGCACTGTGTTACGTGC ATTAAAGTCTATAGTGTGCTGTAG TTTATTATGTAAAATTAAGTTGTAT TCATGTGCTAAAATTTAGAATCTTT CACTTTAGCATCTTAATAGATAGA AGCTGAATCTTCCAGTAAGTTTTG TTTTAGTTTCTTGATTGTAGGTCTC TTGTATGTCCTTGCATAACCCTTTT TCATTCTAGATCTGATGGTTCTAT CTTTTATTATGCAGTTAGAGGATA AATACCAGGAATACAAGCTGAACT TTTACCATGGGAAAAATAAGGACT TCCCATCCAAGTTGCTGAGAGACA TAATTGAGGTCAGTTTTAGATTITTCT TTAGTCGTATTAATTTTAAACTGTT TGCTTATTTTAACAATTTTTTTGTA GGCAAATCTTGCATATGGTTCAGA GAAGGAAAAAACTACGAACGAGA GGCTTGTTGAGCCTCTTATGAGCC TGCTTAAGTCATATGAGGGTGGAA GAGAAAGCCATGCTCATTITTGTITTG TCAAATCCCTTTTCGAGGAGTATC TTGCTGTGGAAGAACTTTTCAGT-
GAT 74 Digitaria |gD- 1983 GACTGAAGAACCATTATTTCTTAC sangui- NA- GTGTTTGTGAGCTTCAAATACAGG nalis Con- TGTCGTTGCTAACATTAAATATGT tig ATCTCTTATTTCTCAGGAAGCATC
AAGCAGGAGCTCAAGCGTTGTTA CTGATTATGTTGGTTATCTCAGCA AAGGTCAGATCCCACCAAAGGTAT ACTATATGCTGAGATGCCCTTATT GCAGATTATGCTTCTTGCTGTTTG ACTTAAAGCAGATTGGTAACTGTG TAATTCCTTTCTGATTTGCAGCAC ATCTCACTCGTCAATTTGACCATT GCTCTAAACATAGAGGGGAGCAA ATACACGGTACTCATCTATAGTTT TTCTCTTAACAGTTTTGTAACCTAC CACTGAGTGTCTTTGAGAAAAACT AAATGTTAAAACTTTGATGTAGAT CGAGACTGTGAGAGGTGGACCCC GCAGCTATAAATTAAGAATGAATG GATCCGAGATTGAAGCAGAGATA CATTCCCTGCGAGATGGTGGACT TCTAATGCAGGTAAATATTGGACC CAACTGTCTCCTTTGTTTTCCTGTT GAAAAAAGTTCTGATCAAACTTTG TTGTATATTCTTCAGTTGGATGGA AACAGTCATGTAATATATGCAGAG ACGGAGGCTGCTGGTACACGCCT TCTCATCAATGGCAGAACATGTTT ACTACAGGTAAACATGGTATTCTT GTTCTCTTCCACATATTTTTTATGC TGAAACACACTACCTGTTACATAT CTTTACTTGAAACTGAAGTTATTG GATCTGGCAATTTTTTACGAATGT TTCTTTCATATGAAGGTCATAGAA ATTATAGGTTACATAGAGGGTAGA GAATACAATTTAGGAAGCTACTAT GACGCATAGCCCTAAGTTATATAA ATTTGCTTGAACGTAGATTTGCTT CGTCCTCTTTATGTTTTCAGCTTG GCATTTTCCATAACGGTGGTTGTT CCATGTGTCAAAGCATCTAATGTT AGCTAGTATTCTCAGTTGCCAAAG ATAAAAGATATCCCAGTTACCTAC TAGCCCACTAAAAGTTTGTAACAA TGTGAAATTTTACTTGAAGGAATA AGCAGTTTGGATTGTTTCAATTCT TAACCGTATTCTCACATCATATGG AAATACATGATATTGTTTITITCITTC TCTTGATTATATTTCACAGAAAGAA CACGATCCTTCAAAGTTGTTGGCT GATACACCGTGCAAACTTCTTCGG TTCTTGGTTGCGGATGGCTCTCAT GTGGATGCTGATACACCATATGCT GAGGTGGAAGTCATGAAGATGTG CATGCCACTGCTAGTGCCTGCCT CTGGTGTCATTCACTTCGTTATGC CTGAGGGTCAGGCCATGCAGGTA TTATTCCTCTTTATTTTTCTCCCOCC TCTGCTCTTGCTTCTTTCATTTTAT AAAAACCTTAAATGTATGTTTTCCT TTTTTTTTCAGGCGAATGACTTAAT AGCAAGATTGGACCTTGATGACC CATCTTCTGTGAGGAGAGCTGAA CCGTTTCATGGCTCCTTCCCCAAA TTGGGACCTCCTACTGCTATTTCT GGCAAAGTTCATCAAAAATTTGCT GCAAGCGTGAATTCTGCACACAT GATCCTTGCAGGCTATGAACATAA TATCAATGAGGTAAGACATATAAT TATTTTTAATTTCAAATTAATTTTCA TTTTTAACTTCCCTTTCATTATCOTT CATCTGCGAAGAACCCAATTTCAT GGTTTATAACACACCACACTATCG CTGAGAGCAATTGGGATTGCGTG GAATAATAGATTGATTAGGGTATA CATGATACAGGATATATAGGCAGC CTTAAGAGGTTTATAGAATCACAG GGCAGCCTTGAGAGGTTTATAGA ATCACAACCAATCAAGGATGCCTG CCTTTCCTAACCAACAGAGCACAG CCAGAGGCCAGCACAAGTCCTGG CACAAATTCCAAGGACCCTACCA-
CATACACTTCTAACAATCC 75 Kochia cD- |7122 ATGGGCGAGTCCGATTCCTGGAC fes a [ocunoreoumcvenes
Con- TCCAAGTCCAAATGATATTGATTC tig AACATATTGGTGTAACAGTTATAG
GAAAAGTGGGCGTATTTTTTGCCA AGGGCAGGGCGGAATGTTATCTA GGGAAGACCCAAATAAGGCAACT TCGGAGGGAAAAATTGATTACCCC AACAGAACAACTCTTTTGAGGAAA TCTGCTACATTACCTGTTGATGAA TTACCTGTTGATGAATTTTGTTATG CTCTTGGAGGGAAAAGACCGATT CGTAGTATTTTGATTGCAAACAAT GGAATGGCAGCTGTTAAATTTATA AGAAGCATTCGGACATGGGCTTAT GAGACCTTCGGAACAGAGAAGGC TATTGTATTAGTAGCAATAGCTAC TCCAGAAGACATGAGAATCAACG CTGAACACATTCGAATGGCTGACC AGTTTGTTGAGGTTCCTGGTGGGÇ ACTAACAACAACAACTATGCCAAT GTGCAGCTCATTGTTGAGATGGC AGAGATGACACGTGTTGATGCTGT TTGGCCAGGCTGGGGACATGCAT CGGAGAACCCTGAGCTTCCAGAT GCACTAAACGCGAAGGGGATTGA ATTTCTAGGGCCTCCAGCTAAATC TATGGCTGCTCTTGGAGACAAAAT TGGTTCATCATTGATTGCTCAGGC CGCAGATGTTCCAACTCTTCCATG GAGTGGCTCTCATGTGAAAGCTC CTGCTGAGAGTTGCCTTGATTCTA TTCCTGATGACATATACAAGGCAG CCTGTGTTTTTACCACAGAGGAAG CAGTTGCTAGTTGTCAGGTTGTCG GTTATCCAGCTATGATTAAAGCAT CTTGGGGTGGTEGGAGGGAAAGGA ATAAGAAAGGTGCATAATGATGAT GAAGTAAGGGCATTGTTCAAGCAA GTGCAGGGCGAAGTTCCTGGCTC TCCCATATTTATAATGAAGGTGGC TTCACAGAGTCGACACTTAGAAGT GCAGTTAATTTGTGATCAATATGG CAATGTAGCAGCATTACATAGCCG TGATTGCAGTGTCCAAAGGCGGC ACCAGAAGATTATTGAAGAGGGTC CAATAAATGTAGCTCCCCAAGAAA CTGTGATAAAACTTGAGCAGGCA GCCAGAAGGTTAGCCAAATATGT GAATTTTGTTGGAGCAGCAACTGT AGAATATCTATACAGCATGGAAAC TGGCGAGTTTTATTTCCTCGAGCT AAACCCTCGGCTACAGGTGGAGC ACCCAGTAACTGAATGGATTGCTG GAATTAACCTTCCAGCTGCTCAGG TTGCAGTTGGCATGGGTATTCCCC TCTGGCAAATTCCAGAAATTCGGC GATTCTATGGTAAGGAACATGGTG GGGGTTATGATGCTTGGAGAAGA ACATCAATTGCTGCGACTGCTTTT AATTTTGACAAGGCACAATCTGTG AAACCGAAAGGTCACTGTATTGCC GTACGTGTGACAAGTGAGGACCC TGATGATGGATTCAAGCCCACTAG TGGGAAAGTACAGGAGTTGATTTT CAAAAGTAAACCAAATATGTGGGC CTATTTCTCTATAMAGTCTGGGGG AGGCATTCATGAGTTCTCAGATTC TCAATTTGGTCATGTCTTTGCATTT GGTGAATCAAGAGGGTTGGCCAT AGCAAATATGGTTCTTGGCTTGAA AGAAATTCAAATTCGTGGAGAAAT TCGCACTAATGTTGATTATACCAT TGATCTTTTAAACTCTTCGGATTAC AGAGATAATAAAATTCATACAGGT TGGTTAGATAGCAGAATTGCAATG AGAGTGAAAGCGGAAAGACCCCC CTGGTTCATCTCTGTTGTGGGAG GAGCACTCTACAAAGCTTTTGCTA GTAGTGCAGCTACAGTTTCAGAAT ATGTTGGCTATCTTGAGAAAGGTC AAATTCCTCCAAAGGTAATTCAAG CACCAGATGCTGTTGAGCATATAT CACTTGTCCACTCTGAAGTTTCTC TGAATATTGAGGGGAGCAAGTAC ACTATTAAAGTGGTGAGGGGCGGÇ TCCAGGAAACTACAGATTGAGATT GAATGAGTCTGAGATTGAGGCTG AAATACATCCATTAAGAGATGGGG GTCTTTTGATGCAATTGGATGGGA AAAGTCACGTGATATATGCTCAGG AAGAGGCAGCAGGAACTCGCCTT CTTATTGATGGACGAACGTGTTTG CTTCAGAATGATCATGATCCTTCA AAGTTAATTGTGGAAACACCTTGT AAGCTACTGCGGTATCTGGTTCCA GATGATAGTCATGTTGATCCAGAT ACTCCTTTTGCTGAAGTTGAGGTT ATGAAGATGTGTATGCCTTTGCTT TCCCCTGCATCTGGTAAAATAAGA TTTAAGATGTCCGAAGGACAACCC ATGCAGGCTGGCGAACTCATAGC AAAACTTGAGTTGGATGATCCTTC AGCTGTAAGAAAAGCTGAACCGTT CCGTGGTAGTTTTCCAACCTTGCA TCCGCCAACTGCTATCTCAGAAAA GGTTCATCAAAAATTTGTTGCAAG TTTGAATGCAGCCCAGATGATTCT TGCTGGTTTTGAACACAACATAGA TGAAGTTGTCCAGAGTTTGTTGAG GTGCCTTGATAGTCCTGAACTTCC TTTCTTGCAATGGCAAGAATGCTT GTCTGTTCTAGCAACACGGCTTCC CAAAGATCTGAGAACTGAATTGGA ATCAAAGTGTCGAAAATTCACAGG AATTACGAATTCTCATAACATTGAA TTTCCTGCTATGGTGTTTAAAGGT GTTCTTGAGGCCCATTTGAATTCA TGCCCTGAAAAGGAGAGAGGAGC TCAAGAGCGGCTCATTGAACCTCT AATGAGTCTTGTTAAATCCTATGA AGGTGGGAGAGAGAGTCATGCCC ATGTTATTGTTCAGTCTCTGTTTGA AGAGTATTTGTCTGTTGAAGAATT GTTCAGTGTCAATATCCAGGCTGA TGTGATTGAACGTCTCCGCCTTCA ACATAAAAATGATCTATCAAAAGTT GTTGATATTGTCCTATCACATCAG GGTGTTAAGAATAAAAATAAATTG ATCCTCCGGCTCATGGAACAACT GGTTTACTCAAATCCTGCCGCATA TCGGGATAAGCTTAAACATTTITTC ACAACTGAACCATAAAACATACTC TAAGTTGGCTCGTAAGGCAAGTCA ATTGCTTGAACAAACCCAGTTGAG TGAACTTCGTTCTAATATTGCCAG AAACCTTTCCGAGTTAGAAATGTT TACAGAAGACGGTGAAAGCATGG ACGTTACAAAAAGGAAAAGTGTTA TTAATGAACGTATGGATGCTCTTG TTAATACTCCGCTTGCTGTTGAAG ATGCCCTTGTTGGCTTGTTCGATC ACAGCGATCATACATTACAAAGGC GGGTTGTTGAGACTTATATCCAGA GGCTTTATCAACCTTATCTTGTAA AGGGAAGTGTCAAGATGCAGTGG CACCGATATGGCCTCATTGCTTCT TGGGAGTTCATGGAGGAGCACAT TGAAAGAGCAAATGCCGCTAATGA TTTGTCCATCAACCAGCCTCTTGC TGAGAAACTCATTGAGAGAAAATT GGGAGTCATGGTCATCATTAAATC TCTTCAGTTTTTGCCAAGAGTGAT TACTGCTGCATTAAAAGAGACCAC GGATAATTCAGATGAAATGATTCC CAGAGGTTCTTTAGATTCAATCAG TCACGGAAATAAGTTGCACATTGC ACTTGTGGGTGTTAATAACCAGAT GAGCTCGTTGCAGGATAGTGGTG ATGAAGATCAAGCTAAAGAGAGAA TTAATAAGTTGGCGAAAATCCTGA GAGAGAAAGAAGTGAGCTCAGTT CTTCTTAACAGTGGTGTTGGGGTA ATTAGTTGCATTATACAGAGAAAT GGAGGAAGAATCCCAATGAGGCA TTCATTCTATTGGTCAGAAGAGAA ACAATACTTTAATGAAGAGCCTTT ACTACGTCATTTGGAACCTCCTCT ATCAATATATCTTGAACTGGACAA GCTCAAACACTATGAAAATCCCAG ATATACTCCTTCTCGGGATCATCA GTGGCACCTGTATACTGTCATGGA CAAGCCATCTATTCGACGAATGTT TTTGAGGACACTTGTCAGACAGCC CACCTCCGAGTTTAGCGGGGTTG AACTAGAAATGCTTAAAACACAAA GGCCTATCTCCTTTACTTCAAGAA ACATACTGAGGTCTTTAACAACTG CAATGGAAGAATTAGAACTCAATG CGCACAATGCTACCTTGAAACCTG ATCATGCTCATATGTACCTGTGCA TTGTAAGAGAGCAACGAATTCAAG ATCTTGTCCCATATCACAGGGAGG TGAACATTGATGATGAACAAGAAG AGATAACTGTTCAGATATATTTGG AAGAGCTTGCGCGTGAAATCCAC AGTTTTGCTGGTGTGAGAATGCAT AAACTAAATGTATGTGAGTGGGAA GTAAAGCTTTGGGTGTCATCTTCT GGCCAAGCCAATGGTTCATGGAG AATCATTGTTAATAATGTGACTGG TCATACATGCACTGTACATGTTTA CCGTGAGTTGGAGGATAACAACC TTCATGAAATGATCTACCATTCAAT ATCTGTTCAAGGTCCTCTCCATGG AATACCAGTGAATGCACCCTATCA ACCACTTGGAGTCATTGCCCGTAA AAGACTTCAGGCCAGGAAAAATA GCACAACCTATTGTTATGACTTCC CACTGAAAGCTGAAATCACCCTTG GGGACGCATGTGAAGCTTACCGC CATCCCCGGAGACGTCCCCAAAA GTCAACGCCGTTCCCGGAAGTCA ATGGCGTCCCGAGGACGTCCCCA AGCCGTCCCCEGGCGCGSTTTCEGT CCCCGTTCTGTCCCCGGCTTTCETCE TACTGCCTTGGAGCAATCATGGG CATCCCAACCTCCGCTGCTGAAG AAACCCACAAACAAAAAAGTTTTG AAAGTCTCAGAGCTAGTATTTGCT GATGCAAATGGCACCTGGGGAAC ACAAGTTGTCCCAACAGACCGTG AACCTGGTCTTAATAATATTGGCA TGGTGGCCTGGTCCATGGAGATG TCAACTCCTGAATTTCCTGATGGA AGGACCATATTGGTTGTAGCAAAT GATATCACCTTCATGGCTGGATCA TTTGGGCCAAAAGAAGATGCTCTC TTCCGGGCAGTTACAGATCTTGCT TGTTCCAAAAAAATTCCTCTGATTT ACCTGGCTGCTAATTCTGGTGCC CGACTGGGTGTTGCTGAAGAGGT AAGAGCGTGCTTTAAAATTGGTTG GTCTGATGAACTGAACCCTGAAC GGGGGTTCCAGTATATCTACTTGA CTCCTGAAGATTATGGTCGTATAG GGTCAGCAGTTATAGCCCATGAG TTAGAACTCCAAAATGGAGAGACT CGGTGGGTTATAGACACTATTGTA GGGAAGGAGGATGGGTTAGGTGT TGAGAACTTATCCGGAAGTGCGG CTATAGCTGGTGCCTATTCAAGGG CATACAAAGAAACTTTTACACTAA CTTTTGTAACAGGAAGAACAGTTG GTATTGGTGCCTATCTTGCTCGCC TTGGGATGCGTTGTATCCAAAGG CTTGATCAGCCCATTATTCTGACA GGCTTTTCAACATTAAATAAACTTC TTGGTCGTGAGGTTTACAGCTCAC AAATGCAACTTGGTGGGCCCAAG ATTATGGGTACAAACGGTGTTGTT CATTTAACAGTTTCAGATGACCTT GAAGGCATTTCATCTATTATCAAA TGGCTTAGCTATGTTCCATCCTAT TCAGGAGGTGAACTTCCTATTTCA CGTTCTTTAGATCCTCCAGAAAGA CAGGTTGAGTATTTGCCTGACAAT TCTTGCGATCCCCGTTCTGCCATA TCTGGTACACTTGACTCTGATGGT AATTGGCTTGGTGGAATTTTCGAC AAAGATAGTTTTGTTGAAACCCTA CAAGGCTGGGCAAGGACAGTTAT CACTGGCCGCGCCAAACTTGGTG GAATTCCAGTTGGGATAGTTGCTG TTGAGACACAAACTGTGATGCAAG CTATCCCAGCTGATCCTGGTCAG CTTGATTCTCATGAGCGAGTTGTC TCACAAGCTGGACAAGTATGGTTT CCGGATTCTGCAACTAAGACAGC ACAAGCTTTGATGGATTTTAACAG GGAAGGACTTCCACTTTTCATTCT AGCTAACTGGAGAGGGTTCTCTG GAGGGCAAAGGGATCTCTTTGAA GGGATTCTTCAGGCAGGTTCCAC AATTGTCGAGAACCTTAGGACTTA TAATCAACCTATTTTTGTTTATATC CCCATGATGGGTGAACTTCGTGG TGGCGCGTGGGTTGTCGTAGACA GTCGAATCAATTCGGACCAGATTG AGATGTATGCTGACCAGACAGCA AAAGGAAATGTTCTTGAGCCAGAA GGAATGATTGAGGTGAAGTTTAGA ACCAAGGAATTAATTGAATGTATG GAAAGGCTTGATCAACATCTTATC AATCTTAATGCAAAACTTGTTGAA GCCAAAAACTCCAATTCATCGGAT GACATCAAACCCCTCAAACAGCA GATAGAAGCTCGGCAGAAGCAAC TTTTGCCTCTATATACTCAAATAGC CACAAAATTTGCTGACTTGCATGA TAGTCCTTATAGAATGGCTGCGAA AGGAGTTGTCAAGGAAGTCCTGG ATTGGAGCAATTCTCGCTCATTCT TCCACAAAAGACTGTACAGGAGA GTAATGGAGGAATCACTTGTCAAG ACTGTCCGAGATGCTGCTGGTGA AGCAATGACCCACAAGTCTGCCTT GGAGTTGATCAAGCAATGGCTTG CTGAGTCTGCCATGGATAGTACTA CTAGAGCGGGAGCTGATGCTTGG GCTGACGATGAAGCTTTCTTCAGG TGGAAAGAAAATCCTGCTAATTAT GAAGAAAAGCTAATTGAGTTACGC ATACAGAAAGTATTGCATCAGCTT TCAAATATTGACAACTCAGCTTCT GATCTGAGAGCTCTTCAGCTTCGT CAGGGTCTTGTTGCCCTACTTCAG AAGGTGAATTCCTCAAGCCGAGC AAATCTAGTAGAGAAACTCGAGA-
AAGTGCTCAATTGA 76 Kochia gD- 17930 | ACTTITGTAGTTTGTAGTTTGTAGT Jess a | Jereonrorecnererociarer
Con- CGCATTAAAATTTGACTAATGCTA tig ATGCTTCCCTAAAATCTCTCCTAA
ACATGTGAATTTCCTTAAATTACCA CCGCAAACTCCATTCAATACTTAG AATTATTCCCTTGAATTCGATCCTA CTCTTCAGTTTCATAGTTTCAACA CTCTTTTATTTAAACTTCCTACAAT CGTCGSTTCTCTTIITITIIITITITGIT TTTCCTAGGCTTCAAATGCAGTAT TATTATTATTATTATTAGTTITTCTT ATTTTACAACTAAATTTTCATTTCA ACACTCAGAAAATTTAAGATGATT CCAATTTCTGAGCGTTGTCATGTT GTTAAATTTCCTATACTCAAATCTT CTTCTCATTGCCGTCTCTTATTTCA CAGTGCAAATGGGACTATGAAATT TCAACTCAAAAAGAGGTATTTTCA TTTTCATTTCTTAGTGTCGTATTTT CGTAATTACGTTGATTTTTGTGTG AATTGTATACTAGTATTACAAAGG ATCCATGATTACATCGTTCAATTG GCATAGATGATGAAATTGTTAGAA ATTTTCGTGCAATTTGCAATGCTT GCTTTCATGATTATTTGTGTTGTTG AAGGGAAATTCTTAATCAATCTCG AGATATGTATTTCGGGTGACATTT TCGTAAATGAACAAAAAACCTTCA AGGAATTTATTTTCACTTTATTTAC GAGAATATACATAGCTTGAGATTG TTTAAGAAATTCCCGATTTGGAGG TATCACTTAGAATATATATATATAT ATATTTTTATTTCATTATTTTAATCA TGGAAAACGATATATACTCGCTAA CTCGCATTTGAATTCACAACTTTT GTACATTGTAGCTTTCTTTCTAGG ATGCATAAAGAACTTGACACTACC AACTAACCGGTGTTTACGATGAAT CATACCCTTTTCTTTGAGCTGATTT TGGGATGTGTCTTTTATATTGGGG TTGGTTTTTGGTAGTGTGTAGTTG AGCTAAATTAAAGCTCTCTTTGGT AAGAAGTAAAATTTTTTTGATGCAA AGTGTTTTCGACAATTTTCTAATTT TATATTGTTTGGTTGACAAAGGAG TGTAAAACCATTTTACATGGAAAA CTTTTCCAACAATATTTTGTACACT CTTGTGGCTACCTCTTTGCACTCC TTCATTTTCGCTATTTCCCATATTG TTTATGATGCAATCAAATAATGGA AAATTGCTTCCATGTAAATTGCTTT CCATTCTAAATTGTTTTCCTTGAAA ATCATTTTACATTGTAAATATTTTA CGCCAAACCAAAATTGACCCTAG GAGTAATATAGTGTGAATTTATCA TATTGTTATATTCGGTAATGCATAC TAGATAATTGTGGTTCATTTTAGTT GTTACTTACTCTTCTAACTGTCGA GTGATTAATACAAGTATGTGTAGT CCAAAGTATTTATATTTTTTAAAAT TAAAAAAAATTGCATTAGATTGTTG GCTCTTGAATTCTACTTGACTCTT GAATGTATGAGTCAAAATAAAACA ATTATTAGTATGTAGCTTTTATACC ATAATAGTTCTGCATTTCAAACAA CCAGTATGTTCTATTCCTTITTAGTA TAAATTAATTCTCTCTITTCTCTGTT AATATTGTAGTTGTGTGGTAAAAT ATGTTAATTACCCAATTAAAAAGCT GCAATCTTGCAATAATATGAGTAT TGCTTATGATAGTAGCTCATGTGT TTCAAAGCTTGTATCATTTTAGTAA GACTATTTGTTTTATGTAATACAAG GTTGTTGTAGCTTGATTACTTTITTG ACATGTAGAATATGCATATCGTGT GAAAATTGGGAATGCTATTCATGT GATAAATTACTCGTACTCTTTCATT TATCTCACGTGGGCTGTGTCGAC ACGACTTGTGTCGGACAACACCG ACACGCGATACTTCAATCTTTTAA CTTTAAACACTACTTTTTTCAAGAA AATGGGCGAGTCCGATTCCTGGA CACCAATGTCGAATTTGACACTTC ATCCAAGTCCAAGTAACATAGTTC ATGTGATATGATGTGATTAGCATG CTGATCAGTGTTTTATTAGATGAT ATTGATTCAACATATTGGTGTAAC AGTTATAGGAAAAGTGGGCGTATT TTTTGCCAAGGGCAGGGCGGAAT GTTATCTAGGGAAGACCCAAATAA GGCAACTTCGGAGGGAAAAATTG ATTACCCCAACAGAACAACTCTTT TGAGGAAATCTGCTACATTACCTG TTGATGAATTACCTGTTGATGAAT TTTGTTATGCTCTTGGAGGGAAAA GACCGATTCGTAGTATTTTGATTG CAAACAATGGAATGGCAGCTGTTA AATTTATAAGAAGCATTCGGACAT GGGCTTATGAGACCTTCGGAACA GAGAAGGCTATTGTATTAGTAGCA ATAGCTACTCCAGAAGACATGAGA ATCAACGCTGAACACATTCGAATG GCTGACCAGTTTGTTGAGGTTCCT GGTGGGACTAACAACAACAACTAT GCCAATGTGCAGCTCATTGTTGAG GTAAATCCTATTTTACTAACACTGA TCTTCATTGTTTTCTCTGATAGAAT ATCGGTTTATAAGAAAAGTTATAA CCTTGCTTGTTGGCCTGTTGATGT GGTTCACATTAAACAACCTTGGTT CATCATAGGTAGTTCAAGCTCCAA CAGTTCATCGTTAACACACATTAA TTCAAGTATCTGTTAATCATTGATC TCAGAGGGTAAACCATTGTTAAAA GGACTTCAATTTATTTTCACTGCTT TTCAGATGGCAGAGATGACACGT GTTGATGCTGTTTGGCCAGGCTG GGGACATGCATCGGAGAACCCTG AGCTTCCAGATGCACTAAACGCG AAGGGGATTGAATTTCTAGGGCCT CCAGCTAAATCTATGGCTGCTCTT GGAGACAAAATTGGTTCATCATTG ATTGCTCAGGCCGCAGATGTTCC AACTCTTCCATGGAGTGGCTCTCA TGTATGCATTGATTTTCTTATTGAC CTTGACAAGCTTTCTITTTTCTCGA GGAGTTTGCTAATCCGTTTTCTTA AATTTCTAATCTTTAGGTGAAAGC TCCTGCTGAGAGTTGCCTTGATTC TATTCCTGATGACATATACAAGGC AGCCTGTGTTTTTACCACAGAGGA AGCAGTTGCTAGTTGTCAGGTTGT CGGTTATCCAGCTATGATTAAAGC ATCTTGGGGTGEGTGGAGGGAAAG GAATAAGAAAGGTGAGCTAGTTGT TTGGGATGATGTCGTCAAGAAATT AAAGCACCGGCTTCAATGCTTATT TATCACCCTTTTCACAGCTTCCAT CCTTGGACATCCTTTTAATTAACT GTCCATTAATATTTACTTGACTTAA ATGATGGACAAATGCTTCAAACTT GTTAGTTAGAGACCCGTTGTGCTA TTTCAATTACAATCGTCTTTCTCTC AAAATATCACAAAGACTCAATAGT TATGCATTTTCAGGTGCATAATGA TGATGAAGTAAGGGCATTGTTCAA GCAAGTGCAGGGCGAAGTTCCTG GCTCTCCCATATTTATAATGAAGG TGGCTTCACAGGTTAGTTATTCTG CAAATTGGTGCTAGAATGTATCAT ATAAGTACTCACAAGTCCATGGCA CTCATGATTTTAGAACTAGTACTG TATGCAAAATTCTTTGATTTTGACA AGTTATTATATGTGCTTCAGAGTC GACACTTAGAAGTGCAGTTAATTT GTGATCAATATGGCAATGTAGCAG CATTACATAGCCGTGATTGCAGTG TCCAAAGGCGGCACCAGAAGGTG GGTCACTAGTGTACTATCAATAAA TTTTTAATCTTCTTGACCAGTTTTG TATTACTTAGGGTCTAAAGTTGTTT TTTTCATAGAGAATCGTGATGCTC ATTGTTCATTGAAGGAATGTATAA ATGATCTTGTTCATTGTATTAATTG ATCAGATTATTGAAGAGGGTCCAA TAAATGTAGCTCCCCAAGAAACTG TGATAAAACTTGAGCAGGCAGCC AGAAGGTTAGCCAAATATGTGAAT TTTGTTGGAGCAGCAACTGTAGAA TATCTATACAGCATGGAAACTGGC GAGTTTTATTTCCTCGAGCTAAAC CCTCGGCTACAGGTATGAAGCAT ACACTTGCACATTGTATATTCATAT TTACCTCGAATAATTACTCAAGAA AGAAAATGTTTTATGTCAATATTTA TGGCATTGCATCTCAATATCCTTT GGATTTATCGTTTTCTACCTTACG TTTGTGGCTCACTTTAATATGACTT GCTTTTGTTAAGGAGCCTTGGGAT TTCTTAGAGTGAGATATGACACTC TTGCCTTTCAACTTTTGTGAACCA TGTCTGATACTCCCTCCATTTCCT TTTGTTTGTTTGATTTATATCTTGA GGGGTGATATTATTCATAGGTAGA GAGATTCCTCTAAATTTATAAGAT GAGACATAGCTCTGAGGGGTCTT GTTGAATTCATCTTGATGAGTACT TTAAATCAAAGCCTTGATGAGTAC TTCAATAATATTAAATTTTTAGAAT TTTTATTCTTATATAGTTAAAGATA CTAACAACTAAAAATTTGCTCCAA CAAATGTGTGATAATGAATCGGGA CAAAAGAAGGGAATGGAGGGAGT ATTACTAAGAATTAGCAATCCTATA TGATCATGTGATGGATGAAAAAAT CTTATTGAAGACTTTTCTGATAATA TTGTATATAATGTCTGACATATGT GTAGGTTTTATTATATTTAATTTTA AAAAATTCCTGTTTGGAAAATCCG GTTAATTTTATTGGTTATTTATCTA ATTCCTTCTTTTGTTCGCGTTTGAT AAATACAGGTGGAGCACCCAGTA ACTGAATGGATTGCTGGAATTAAC CTTCCAGCTGCTCAGGTTGCAGTT GGCATGGGTATTCCCCTCTGGCA AATTCCAGGTAGCTAGCATGTTCC CTTTCTGATTATCGAACTTATGTG CTTCATGTTGTTCTTGTGCATGAT TGTGCTTGCTTTTGAATTATCAAAA TAGAAATTCGGCGATTCTATGGTA AGGAACATGGTGGGGGTTATGAT GCTTGGAGAAGAACATCAATTGCT GCGACTGCTTTTAATTTTGACAAG GCACAATCTGTGAAACCGAAAGG TCACTGTATTGCCGTACGTGTGAC AAGTGAGGACCCTGATGATGGAT TCAAGCCCACTAGTGGGAAAGTA CAGGTTAGTAATACTAGTGTTTAA CAGTTCAAACTACACTCTCAATTG ACTGCCTTGTCTGTTTTGTGATTC ATGTAAAATTATTTATTTCATTGGT TCCTTTTCTAGGAGTTGATTTTCAA AAGTAAACCAAATATGTGGGCCTA TTTCTCTATAAAGGTATGTCTTTAT TCTTCAATTTTCACATCATCCTTTT ATGGATTCATCCACGAGCTTAACA ATGATCAACATTGTGACGCAGTCT GGGGGAGGCATTCATGAGTTCTC AGATTCTCAATTTGGTAAGTTTAAA GCACATTTTAAAGATGACTAGCAA TGAAATGACAATTATAGCTGCCTT TTAAGAATGAAGTTCTTCAACATC ATATTAGGGGTTCTCTAATTTAAG TCTGCTGCAAATGGATAAGGAACT ATGCTGTTGTACATGTGAAATGAG ATATATTGGTTTTTCGTAGTGTGT CACAGCAGACGGTAAATGCTCTT GTTAATTGTTGATGATTAATTGGG ATTTAGCATTCATGGTGTAATCTG CTCTTGCACTATCAAGTCTCATGG AATTAACATGTCATTTTTTITATCG ATTATTTTTGGTTTTAAAACATCCT TTATCTATTITTITTTATTITITITAT AGAAGGCTAATGTTAGTTAATTTG TTTGTAGGTCATGTCTTTGCATTT GGTGAATCAAGAGGGTTGGCCAT AGCAAATATGGTTCTTGGCTTGAA AGAAATTCAAATTCGTGGAGAAAT TCGCACTAATGTTGATTATACCAT TGATCTTTTAAACGTGAGCCTTGT ACATGATTTTTTTTCCTCCCTACAC TTTCCACTGTTTITTTCAATTAGAAG CTAAACTTGTCTTCGTTTTTCCTIT CTCCAGTCTTCGGATTACAGAGAT AATAAAATTCATACAGGTTGGTTA GATAGCAGAATTGCAATGAGAGT GAAAGCGGAAAGACCCCCCTGGT TCATCTCTGTTGTGGGAGGAGCA CTCTACGTATGTACAACTTTTITITC TCTAAAATTTGTTTCCTTCCAAAAG ATTCACATGTCATTTITCGTCTTTT TTTATAACGAATAATTTTAAATGAT TTCTCTCTTCTTTCTCCCTATCOTTC AGAAAGCTTTTGCTAGTAGTGCAG CTACAGTTTCAGAATATGTTGGCT ATCTTGAGAAAGGTCAAATTCCTC CAAAGGTAATTCAAGCACCAGATG CTGTTGAGGTATACTGGTTTTITT AAACACTAATTGTTTCTTTCAGTAA ATTACATCAATTTTTGTGTGGATTG CAGCATATATCACTTGTCCACTCT GAAGTTTCTCTGAATATTGAGGGG AGCAAGTACACTGTAAGTATATTA TTATAACTGATGTGAATTTTATATT TCATTTTTCGATTTCGTCTGTTTTC TTGTTAATCATCATAACATGGTTAA TGCTGTTCTCTAGATTAAAGTGGT GAGGGGCGGTCCAGGAAACTACA GATTGAGATTGAATGAGTCTGAGA TTGAGGCTGAAATACATCCATTAA GAGATGGGGGTCTTTTGATGCAA GTAAGAACTTAACTTTTATTCATTC ATATATTCATGATTGAGGGCAATT GTCAAATTATACACATATAGGAGT TATAATATGTGTAGAGTTAAAATTG CGAGTGAAAGCTGAGATATTACTC GATGTATTTAGTATATCATTCACCA TAGAATGCTTGAGTTACTTGCGTT AAATTAAAAAAAAAAAGGAAAGAG TAGAAATTAGAGAGTCTAAAGTTT CTGTGGTCATAATGATATGTCTAA TTGAACGCACCCCAATGTGTTTCA GTTATTTTTTTACCCCTAACTTAGG AGGGAAAACTGACTTAGCGGCTT CCCCTCTAGCATAGGATATAAGTG CTCCAAACTCTTAGAATATCTAAAT TTGAAAAACTTATAATGTATTATTG ACATTCTTTCAGAGAATGCTTTTCT GTGTGAACTCCTTAAGTATGTTAA TAGCAATCCCGCAACCCTGTTTCA CATTATATAGGTATTTGTTTCTTAT TAGATGATATTCCATATCTCCATAT AAGATCTTTCTTCTTACCAATTCAA GCCATATATTTTTTGGATTAAGAA GATGATATTCACAAAAGGTTTGCG TTATGATGATACTTAATATACCCAC ATGTTTCATATTTTCATTGACTTAA ACGCTATTTCTTAGAAAAGTTGGA GTTGTTGATCCAATGTATGTGCTG GTTTCTCATCCCTTTGTTTTCAATT AGCTATGGATTTTGAGCTCTTCTG TACATTTGAATGTGATGTAGTTGG ATGGGAAAAGTCACGTGATATATG CTCAGGAAGAGGCAGCAGGAACT CGCCTTCTTATTGATGGACGAACG TGTTTGCTTCAGGTACCATCATGT TATTTAATTGCATAGTATTTCTAAA CATTTACCAAGCGTAACATGCTAT TACATTTTCCACTTCTTCAATATTC AGAATGATCATGATCCTTCAAAGT TAATTGTGGAAACACCTTGTAAGC TACTGCGGTATCTGGTTCCAGATG ATAGTCATGTTGATCCAGATACTC CTTTTGCTGAAGTTGAGGTTATGA AGATGTGTATGCCTTTGCTTTCCC CTGCATCTGGTAAAATAAGATTTA AGATGTCCGAAGGACAACCCATG CAGGTTAGCATAGGTTTTAGTAGA TCGATATGTTAACTAAATATACTTC AAAAGTTTCTTCTAAGTGAAGGTT CACTGTGTAGGCTGGCGAACTCA TAGCAAAACTTGAGTTGGATGATC CTTCAGCTGTAAGAAAAGCTGAAC CGTTCCGTGGTAGTTTTCCAACCOT TGCATCCGCCAACTGCTATCTCAG AAAAGGTTCATCAAAAATTTGTITTG CAAGTTTGAATGCAGCCCAGATGA TTCTTGCTGGTTTTGAACACAACA TAGATGAAGTAAGTATTTTAATTGT GAATTCAAAAATATTGAGCACTAT ATTATATAGATGAAGTATTTCAGTT ATGAATTAAGCATAGATGATGTGA GTATTACTCTAAGGGGGCTGATG CAAAAATTTGAGAGTAAATGTATA TTTATATTTTGTTTGGTTCCCTTAT CTGAAAGATTCTTTACAAAAGAGT TTTCTAATTCTCAGGTTGTCCAGA GTTTGTTGAGGTGCCTTGATAGTC CTGAACTTCCTTTCTTGCAATGGC AAGAATGCTTGTCTGTTCTAGCAA CACGGCTTCCCAAAGATCTGAGA ACTGAAGTATGTTACTAAAATCTG TATGCAATTTTTTTCCATATTTGAT AAACACCTGCTGTCTTTAGCAGTC TTTATCTTCTTTGGTCTTTCCCOTCT CTCTCTCTCTCTCTCTCTCACCOCOT GTGTATAATTCACATTATTTTTCCA TGTTTCCCTGTCTTTGGTATTCTC AGTTGGAATCAAAGTGTCGAAAAT TCACAGGAATTACGAATTCTCATA ACATTGAATTTCCTGCTATGGTGT TTAAAGGTGTTCTTGAGGTTAGTC TTTCTTTTTGCTACCCTTCTATATA TGCTATATATTTTAGTATTACTTAC ATAAGTATTTTGTTTACAGGCCCA TTTGAATTCATGCCCTGAAAAGGA GAGAGGAGCTCAAGAGCGGCTCA TTGAACCTCTAATGAGTCTTGTTA AATCCTATGAAGGTGGGAGAGAG AGTCATGCCCATGTTATTGTTCAG TCTCTGTTTGAAGAGTATTTGTCT GTTGAAGAATTGTTCAGTGTCAAT ATCCAGGTTTGTTATTGCCGTGCA AATTAATCAGTTTATCGATGATCAT TGGTCTTTATGTTTTTTCCTCGATT GGTAGATTGGTTATGATGTTATGA CTCTAGAGTAAAGGTGGAACCAG AAAAATGTTTTGGAGGGGGCCAA AATATTTGTTTTGTATTATTGGAGG GGGCCGAATACAAAAATTAGCTTA ATTTTTCCCATATTTAACCTATTTT TTAAAGAAAAATAAAAAATTGGCG GGAGTCGTGGCCCCCACCCEGCCC CCATGTTCTGCCATTGCCCTAGAG GCTACAGAATCTTTGGAGTACCTT ATGTCTCAGTGAATTATAGTAGCA TCCTTTGAAGTATTACTTTGTTTIT TCAAGAAATAGCAGTTCATGTCTT TGGTTGTTGGCTTGTAATTTGTGC ACTGTAATGCAAGCTTAGGACTAG AAGAAACAGTTTATTTATACGCTAT GAATTATGATCCTGGTAGGCTGG CATCGTTCCACTGTAATATGATTC TGATTTCAATCTATACAGGCTGAT GTGATTGAACGTCTCCGCCTTCAA CATAAAAATGATCTATCAAAAGTT GTTGATATTGTCCTATCACATCAG GTAAGCAGGAAATTTCAAATAATA CAAAATAAAATTTTCTGAGTTITTCT TTTTATTITCTTITCITTTITITTCCOCO ACTTTCCCTTGTACTGTCTTCTAG ACTTGTTTACTGTGTAGTAATAAT GGTTTTCAGGGTGTTAAGAATAAA AATAAATTGATCCTCCGGCTCATG GAACAACTGGTTTACTCAAATCCT GCCGCATATCGGGATAAGCTTAAA CATTTTTCACAACTGAACCATAAA ACATACTCTAAGGTTAGAGATGAT TCAACTTTTTGCATTATTGTCACAC TACAACATTCACAAAAAGGTCATT AAGTTTATACACTAATTAATTCCTT CGCTATATGCAGTTGGCTCGTAAG GCAAGTCAATTGCTTGAACAAACC CAGTTGAGTGAACTTCGTTCTAAT ATTGCCAGAAACCTTTCCGAGTTA GAAATGTTTACAGAAGACGGTGAA AGCATGGACGTTACAAAAAGGAAA AGTGTTATTAATGAACGTATGGAT GCTCTTGTTAATACTCCGCTTGCT GTTGAAGATGCCCTTGTTGGCTTG TTCGATCACAGCGATCATACATTA CAAAGGCGGGTTGTTGAGACTTAT ATCCAGAGGCTTTATCAAGTAATA TCTAAGTTTCAACATTAAACTTTAA CAATCATTTGATAATATTATGTCAT TTAACTCTCTTTTTITGTGGGTAAC CTCTTTTCTCAGCCTTATCTTGTAA AGGGAAGTGTCAAGATGCAGTGG CACCGATATGGCCTCATTGCTTCT TGGGAGTTCATGGAGGAGCACAT TGAAAGAGCAAATGCCGCTAATGA TTTGTCCATCAACCAGCCTCTTGC TGAGAAACTCATTGAGAGAAAATT GGGAGTCATGGTCATCATTAAATC TCTTCAGTTTTTGCCAAGAGTGAT TACTGCTGCATTAAAAGAGACCAC GGATAATTCAGATGAAATGATTCC CAGAGGTTCTTTAGATTCAATCAG TCACGGAAATAAGTTGCACATTGC ACTTGTGGGTGTTAATAACCAGAT GAGCTCGTTGCAGGATAGGTATA GATTCTATCCTTGTAGTTTCAGCA AGATTTTAAATGTGGACATTATTG GACCATCCGGTTTTTTTGAAGAAA TATGCTTTGCTTCAATTATACAGTT GCTCTTAATATTATCCATTCCAGC CTTTTGCTTAACCTTITTITTGTCTTT GTGGTTTATGAAATTTATTTTTATA CTATTCAGTGGTGATGAAGATCAA GCTAAAGAGAGAATTAATAAGTTG GCGAAAATCCTGAGAGAGAAAGA AGTGAGCTCAGTTCTTCTTAACAG TGGTGTTGGGGTAATTAGTTGCAT TATACAGAGAAATGGAGGAAGAAT CCCAATGAGGCATTCATTCTATTG GTCAGAAGAGAAACAATACTTTAA TGAAGAGCCTTTACTACGTCATTT GGAACCTCCTCTATCAATATATCT TGAACTGGTAATAAAATTCTGAGC AAGAAGCTGTTGCTTTGTITTTGTTC GTTCTTTTCTTGTTTTTTAATATGG GCCAAATCATTATCTTTAATATTTT TATCACTATATGATATAGTTATAAG GTATTTGGCTCACAATTTTCATTAT ACAGGACAAGCTCAAACACTATGA AAATCCCAGATATACTCCTTCTCG GGATCATCAGTGGCACCTGTATAC TGTCATGGACAAGCCATCTATTCG ACGAATGTTTTTGAGGACACTTGT CAGACAGCCCACCTCCGAGTTTA GCGGGGTTGAACTAGAAATGCTT AAAACACAAAGGCCTATCTCCTTT ACTTCAAGAAACATACTGAGGTCT TTAACAACTGCAATGGAAGAATTA GAACTCAATGCGCACAATGCTACC TTGAAACCTGATCATGCTCATATG TACCTGTGCATTGTAAGAGAGCAA CGAATTCAAGATCTTGTCCCATAT CACAGGTTCTAATTAATCATCTTAA TTTTCTGTGTTTCATTCGTGGTCAT TGATGCAACTTATGCCTTAATAGA TATTATTTTGACCCATTGATCCAG GGAGGTGAACATTGATGATGAAC AAGAAGAGATAACTGTTCAGATAT ATTTGGAAGAGCTTGCGCGTGAA ATCCACAGTTTTGCTGGTGTGAGA ATGCATAAACTAAATGTATGTGAG TGGGAAGTAAAGCTTTGGGTGTC ATCTTCTGGCCAAGCCAATGGTTC ATGGAGAATCATTGTTAATAATGT GACTGGTCATACATGCACTGTACA TGTAAGTTTGAATTTTGATTATTITTT TCCTATAACTTTCTGTACATCAAC CATGTTTAGTGATTTCTTTCAACAC TCTGATATTTATGCCAGTTTTTGTA AGAATTATAGAAATACAGTAGCAA TGTTTTGATAGCCCAGGTTCTCTC TTTCTCCCAAATTAATCTTTGTGTC AATGCATGACTTTGCCGCATCAAT ATCTTAAATAATTTATGATTATAAA CTATAAGAATATGATACTATGAGA AATTGAAAATATACATCGAGAGAA ATCTAAATACACCTTCCATAACCTT TGATTTATTATTITTATTTTITTAATG GAAAAACAATGGGCAAAGGTGAT ACATGAATCATGTAAAACACAAAC TTTGATTTTACATATGGGATGAAG GGACTAGTAATGGTTTGTATATTG GCACTGACAAAGAAAAGTTTATTC ATGATTAATTTACGTCTTGTATACG TGTATCACATAATGTCTTCTTTAGT TTGATGACCTTTTTTCTACTAATGT TATGCAGGTTTACCGTGAGTTGGA GGATAACAACCTTCATGAAATGAT CTACCATTCAATATCTGTTCAAGG TCCTCTCCATGGAATACCAGTGAA TGCACCCTATCAACCACTTGGAGT CATTGCCCGTAAAAGACTTCAGGC CAGGAAAAATAGCACAACCTATTG TTATGACTTCCCACTGGTAAGAAA TATTAAACTCCACTATACCCCAAT ACTACAAAAGCAGAATTTTACTAT ATTAGGTTTCCTTCCCTCCCGAAT TTTTTTAAAAAATAAGAGTTAATAC ATGACTTGCATTCGAGTGTAACTA TGTTCTTATTAACGCTCAACTAGT AATGCAATGGGAATATAAATCTAA ATTCTAAGAGGGAGGTGGGGTTC AGTAACTGTGGGACTAGGTTGCA CCGATACGGGTACGGGGACATAT ACGGGTACGGGAACGGGGACGG GAAACGACAATTTTAAAAATTCTT GGGTACGGGGACGGATTTGGGAA CGACAATTTATTAAATATAAATTTT TATTTTAAAAAAAAATGAGCATTGT GATCATTTTAATAAAAAAAATGCAA CAAAATAAAAATCATAGTTAATACA AATAATTTAGTCCAAAGTAAAAGG CAAGTAGACAACATTTAATITTITTT TAAACATAACCAGAAAACATAAAT TTAATAGGGTAAATAAAAAATGGT GAAATCCAAAAAATTAAATAAATG ACACAAATAAGCACACATTCACAA CCACACATTTACAAATCACAAATT CACAACCACATAAAATGAATTAAA GTGGAATAGTTTACTGACATGCTT TGGAAGACAATAGAAAAAGTGAAA GAGAAGATTAGAAGAAGAAAGTG AGATTTAAGAAGCCACGAAGTGAA GCCTAGCGCCATAGTGGAATAGT CAAGCCTCAACATCGTCGAATAGT GTAGCCTTGCGCCATCGCCATTG AGAGTGAGTGGCAGAACCACCGT TTGCCGTCACCGTGGTGTAATGC ATCGTCGTCGAGAGGAAGAGAGA GAGACCCTAGAATTTGAAATTGGT TTGTTTTTTGTTGTGCCAAGTGGT TTATTCAACATTCTATTGTAATTTT GTTGTTTTATAAACTAAAAGAAAG CTGAAATCACCCTTGGGGACGCA TGTGAAGCTTACCGCCATCCCCG GAGACGTCCCCAAAAGTCAACGC CGTTCCCGGAAGTCAATGGCGTC CCGAGGACGTCCCCAAGCCGTCC CCGGCGCGTTTCEGTCCCOGTTC TGTCCCCGGTACGGGGGACGCTGÇE GCTATGTGGCGTCCCCGTGCAAC ATAGCTGTGGGACCTTGTAAAGGT TTAAAGTTTGGTGGAGATGCTGG GTTTATAATTAGTTTAGGACGAAA CTGCCAAGTTTTCTATTGTATGTA ATTTATTGGTTATGAAAGTAAAAAA TCGTGATTGTTATGCAAATGATTG TACCTATAGTGATTGTGTGACAAT GTTGTCAAATGTATAAGCATTGCA ATTTTTTTGAGATAAGGGAACCGT AAATAAAAATACAACGCATGGCTT GGATGTTACCGTCATTACCGATTT TTGTCCTATGTAGTGGTATCTCAA ATTTTTATATTTCACTTTGGAGCGA TCAACTTGCTTTAGGTGCTAGTAT TTATCTGTTTTTCTATGGGAAAATT GACTTGTAATTGTTGGGAATGTTT TTCTTAGGCTTTCTCTACTGCCTT GGAGCAATCATGGGCATCCCAAC CTCCGCTGCTGAAGAAACCCACA AACAAAAAAGTTTTGAAAGTCTCA GAGCTAGTATTTGCTGATGCAAAT GGCACCTGGGGAACACAAGTTGT CCCAACAGACCGTGAACCTGGTC TTAATAATATTGGCATGGTGGCCT GGTCCATGGAGATGTCAACTCCT GAATTTCCTGATGGAAGGACCATA TTGGTTGTAGCAAATGATATCACC TTCATGGCTGGATCATTTGGGCCA AAAGAAGATGCTCTCTTCCGGGC AGTTACAGATCTTGCTTGTTCCAA AAAAATTCCTCTGATTTACCTGGC TGCTAATTCTGGTGCCCGACTGG GTGTTGCTGAAGAGGTAAGAGCG TGCTTTAAAATTGGTTGGTCTGAT GAACTGAACCCTGAACGGGGGTT CCAGTATATCTACTTGACTCCTGA AGATTATGGTCGTATAGGGTCAGC AGTTATAGCCCATGAGTTAGAACT CCAAAATGGAGAGACTCGGTGGG TTATAGACACTATTGTAGGGAAGG AGGATGGGTTAGGTGTTGAGAAC TTATCCGGAAGTGCGGCTATAGCT GGTGCCTATTCAAGGGCATACAAA GAAACTTTTACACTAACTTITTGTAA CAGGAAGAACAGTTGGTATTGGT GCCTATCTTGCTCGCCTTGGGAT GCGTTGTATCCAAAGGCTTGATCA GCCCATTATTCTGACAGGCTTTTC AACATTAAATAAACTTCTTGGTCG TGAGGTTTACAGCTCACAAATGCA ACTTGGTGGGCCCAAGATTATGG GTACAAACGGTGTTGTTCATTTAA CAGTTTCAGATGACCTTGAAGGCA TTTCATCTATTATCAAATGGCTTAG CTATGTTCCATCCTATTCAGGAGG TGAACTTCCTATTTCACGTTCTTITTA GATCCTCCAGAAAGACAGGTTGA GTATTTGCCTGACAATTCTTGCGA TCCCCGTTCTGCCATATCTGGTAC ACTTGACTCTGATGGTAATTGGCT TGGTGGAATTTTCGACAAAGATAG TTTTGTTGAAACCCTACAAGGCTG GGCAAGGACAGTTATCACTGGCC GCGCCAAACTTGGTGGAATTCCA GTTGGGATAGTTGCTGTTGAGACA CAAACTGTGATGCAAGCTATCCCA GCTGATCCTGGTCAGCTTGATTCT CATGAGCGAGTTGTCTCACAAGCT GGACAAGTATGGTTTCCGGATTCT GCAACTAAGACAGCACAAGCTTTG ATGGATTTTAACAGGGAAGGACTT CCACTTTTCATTCTAGCTAACTGG AGAGGGTTCTCTGGAGGGCAAAG GGATCTCTTTGAAGGGATTCTTCA GGCAGGTTCCACAATTGTCGAGA ACCTTAGGACTTATAATCAACCTA TTTTTGTTTATATCCCCATGATGG GTGAACTTCGTGGTGGCGCGTEGG GTTGTCGTAGACAGTCGAATCAAT TCGGACCAGATTGAGATGTATGCT GACCAGACAGCAAAAGGAAATGT TCTTGAGCCAGAAGGAATGATTGA GGTGAAGTTTAGAACCAAGGAATT AATTGAATGTATGGAAAGGCTTGA TCAACATCTTATCAATCTTAATGCA AAACTTGTTGAAGCCAAAAACTCC AATTCATCGGATGACATCAAACCC CTCAAACAGCAGATAGAAGCTCG GCAGAAGCAACTTTTGCCTCTATA TACTCAAATAGCCACAAAATTTGC TGACTTGCATGATAGTCCTTATAG AATGGCTGCGAAAGGAGTTGTCA AGGAAGTCCTGGATTGGAGCAAT TCTCGCTCATTCTTCCACAAAAGA CTGTACAGGAGAGTAATGGAGGA ATCACTTGTCAAGACTGTCCGAGA TGCTGCTGGTGAAGCAATGACCC ACAAGTCTGCCTTGGAGTTGATCA AGCAATGGCTTGCTGAGTCTGCC ATGGATAGTACTACTAGAGCGGG AGCTGATGCTTGGGCTGACGATG AAGCTTTCTTCAGGTGGAAAGAAA ATCCTGCTAATTATGAAGAAAAGC TAATTGAGTTACGCATACAGAAAG TATTGCATCAGCTTTCAAATATTGA CAACTCAGCTTCTGATCTGAGAGC TCTTCAGCTTCGTCAGGGTCTTGT TGCCCTACTTCAGAAGGTATCTCT AAGGTTCCTCCACACACACACACA CCCCACCCACCAAAAAAAACACAC ACACACACATTCACAAGAAAAGTA GAATTGCTAGTGAAATAACTTCAT CGTGTTCAATGCAGGTGAATTCCT CAAGCCGAGCAAATCTAGTAGAG AAACTCGAGAAAGTGCTCAATTGA TTTGGTAATGATCCTGCAGAAAAA CCTCTTGGTATATGGTGGTATGCA AATGCCATATCTGAAAGATTGATT AGGCAAGTTGAGACAGAGACAGG CACAGTTGTAATAATGGGATCTAT CAAACCAGAAGACGTTATAACTAA GCTCAAAGATGATGGTGATTTTGA CCGTCTTCEGTCTCAAAATCATTCG TAAGCTCAAACAAAACGTATTTCT TTCTCCTTTTCATCTTCTACTGTAT ATTAAATGGTTTAAAATTTGATCTT GATTAATGGGTAATCTTTATAATTT TATCTTTTTTATTATAATACAAGAA TGATATGCATATTTTTATTTTGTITTA TTAATTACCAAATGCACTTCAGTTT ACATTGCCGGTTTTGAAGTTTTGG AAGCAGAATTGGGGTTAGAATGCT AGATATTATTGCTTGTTGATCATTT ATTCAGTTACTTACATTGTTTGGTT GAAATCGGAATTAAAAGAGCACAA ATTGTATGGTTTCTAACTCGACTT CACAATAAGAGTATAGATGCTCAC TGTTGTGTTGTGTGTTITTGTITTITITG TTAAGAAATATTGGTTTTGATTGAT GATGCTCCAAGCCTCGAGTGAGC GTGTTGATGAAATAGAGTACTGAA TTAAAGGTTATCATTTTATCGAATG TCAGATTAATTGTTAATTGTTGCTC GGAGTCGGAGTTTAAATGAGAATC ATTTTATCGAATGTCTTAAGTTATC AGGGCAGATATTTITTITITCTAGTG GGTATGGACTCTTGAGCCTCTTITT TTCTGTATCAAACTGTCCTGTTGG TTGTTCAAATTATGCAAATCATGAA GAGATTACTTTGGTCTCAGGTTTG CTTCGCCATCCTTCCCAATGAATC GTCAGGATTCATTTTCAATTAAATC TTATGTATTCACGGGTTCCTTCGT CCCGGTCGCTTCTTAGTTAATGTT CTAGCCCGGAGCCTTGTTGTTGG ATGGTTTGATCTACTATAGAGTTC ATTTTCTGACTTGTTTGGCATTTGT TAATGGGCATTGATACGAGTTGTT TACCGTATTAAATTAATTATTTATA AAATTTATCTTAGTCGTTCAAAAAT ATATACAAGTAATTTAAAATTCAAT CTAAAGTGAAGTATAAGTACATAT ACACATAATATTTACGCTATTTACA GAATTATACTAATAATCGAATTAAA ATAAGTCAATTAGAGTAGTAAAGG AATTAACAAGGTATTTAACTAAAAC AATTGATGAGTAAGAAGAACTGAT GAATTTGTACTCAAGAACACCCAA ACGATACTCCGCTTCAACCTCACG ACTCGATGTCATTCTCGTTCGACC TTGAATTCAAGACTAAGCTACCTT TCAATTGTTGTCTCCTCTTCCAATT GCTCCAATCGAAAATCCTATCAAA ACTCTTACTCTCAATTGCTCTCAA AATATCGGCTAAGTTGTGTGTCAA CAATAGGTCTATTATGGTCCTGA-
GACCATGTGG 77 Kochia gD- [12931 | AANTAGTAAMAAACCTAGTGAACTTT scoparia | NA- GTAGTTTGTAGTTTGTAGTGTGCA Con- GTGTGCAGTGTGCAGTGTCGCAT tig TAAAATTTGACTAATGCTAATGCTT
CCCTAAAATCTCTCCTAAACATGT GAATTTCCTTAAATTACCACCGCA AACTCCATTCAATACTTAGAATTAT TCCCTTGAATTCGATCCTACTCOTT CAGTTTCATAGTTTCAACACTCTTT TATTTAAACTTCCTACAATCGTCGT TCTCTTTTTIITITITGTTTTTCCTA GGCTTCAAATGCAGTATTATTATT ATTATTATTAGTTTTTCTTATITTTAC AACTAAATTTTCATTTCAACACTCA GAAAATTTAAGATGATTCCAATTTC TGAGCGTTGTCATGTTGTTAAATT TCCTATACTCAAATCTTCTTCTCAT TGCCGTCTCTTATTTCACAGTGCA AATGGGACTATGAAATTTCAACTC AAAAAGAGGTATTTTCATTTTCATT TCTTAGTGTCGTATTTTCGTAATTA CGTTGATTTTTGTGTGAATTGTATA CTAGTATTACAAAGGATCCATGAT TACATCGTTCAATTGGCATAGATG ATGAAATTGTTATAAATATCGTGC AATTTGCAATGCTTGCTTTCATGA TTATTTGTGTTGTTGAAGGGAAAT TCTTAATCAATCTCGAGATATGTAT ATCGGGTGACATTTTCGTAAATGA ACAAAAAACCTTCAAGGAATTTAT TTTCACTTTATTTACGAGAATATAC ATAGCTTGAGATTGTTTAAGAAAT TCTCGATTTGGAGGTATCACTTAG ATTGTTTAATTTCATTATTTTAATC ATGGAAAACGATATATTCTCGCTA ACTCGCATTTGAATTCACAACTTTT GTACATTGTAGCTTTCTTTCTAGG ATGCATAAAGAACTTGACACTACC AACTAACCGGTGTTTACGATGAAT CATACCCTTTTCTTTGAGCTGATTT TGGGATGTGTCTTTTATATTGGGG TTGGTTTTTGGTAGTGTGCAGTTG AGCTAAATAAAAGCTCTCTTTGGT AAGACGTAAATTTTTTTGATGCAA AGTGTTTTCGACAATTTTCTAATTT TATATTGTTTGGTTGACAAAGGAG TATAAAACCATTTTACATGGTAAAC TTTTCCTTCAATATTTTGTACACTC TTCTGGCTACCTCTTTGCACTCCT TCATTTTCGCTATTTTCCATATTGT TTATGATGCAATCAAATAATGGAA AATTGCTTCCATGTAAATTGCTTTC CATTGTAAATTGTTTTCCTTGAAAA TCATTTTACATTGAAAATATTTTAC GCCAAACCAAAATGACCCTAGGA GTAATATAGTGTGAATTTATCATAT TGTTATATTCGGTAATGCATACTA GATAATTGTGGTTCATTITTAGTTGT TACTTACTCTTCTAACTGTTGAGT GATTAATACAAGTATGTGTGGTCC AAAGTATTTATATTTTTTAAAATTA AAAAAAATTGCATTAGATTGTTGG CTCTTGAATTCTACTTGACTCTTG AATGTATGAGTCAAAATAAAACAA TTATTAGTATGTAGCTTTTATACCA TAATAGTTCTGCATTTCAAACAAC CGTATGTTCTATTCCTTTTAGTATA AATTAATTCTCTCTTTCTCTGTTAA TATTGTAGTTGTGTTGTAAAATATG TTAATTACCCAATTAAAAAGCTGC AATCTTGCAATAATATGAGTATTG CTTATGATAGTAGCTCATGTGTTT CAAAGCTTGTATCATTTTAGTAAG ACTATTTGTTTTATGTAATACTAGG TTGTTGTAGCTTGCTTGCTTTTGA TATGTAGAATATGCATATCGTGTG AAAATTGGGAATGCTATTCATGTG ATAAGTTACTCGTACTCTTTCATTT ATCTCACGTGGGCTGTGTCGACA CGACTTGTGTCGGACAACACCGA TACGCGATACTTCAATCTTTTAACT TAGAACACTACTTTTTTCAAGAAAA TGGGCGAGTCCGATTCTTGGACA CCAATGTCTAATTTGACACTTCAT CCAACTCCAAGTAACATAGTTCAT GTGATATGATGTGATTAGCATGCT GATCAGTGTTTTATTAGATGATATT GATTCAACATATTGGTGTAACAGT TATAGGAAAAGTGGACGTATTTTT TGCCAAGGGCAGGGCGGAATGTT ATCTAGGGAAGACCCAAATAAGG CAACTCCGGAGGGAAAAATTGATT ACCCCAACAGAACAACTCTTTTGA GGAAATCTGCTACATTACCCGTTG TTGATGAATTTTGTTATGCTCTTG GAGGGAAAAAGCCGATTCATAGT ATTTTGATTGCCAACAATGGAATG GCAGCTGTTAAATTTATCAGAAGT GTTCGGACATGGGCTTACGAAAC TTTTGGAACAGAGAAGGCTATTGT ATTAGTAGCAATGGCTACTCCAGA AGACATGAGAATCAACGCTGAACA CATTCGAATGGCTGACCAGTTTGT TGAGGTTCCTGGTGGGACTAACA ACAACAACTATGCCAATGTACAGC TCATTGTTGAGGTAAATCCTGCTT TAGTAACACTGATCTTCCGTGTTT TCTCTGTTAGATTACGAAATACTC ACATTAGCCACAGTGTATGAGAAA AGATATCACCTGTCCTGTTGGCCT GTTGATGTTCATCATTGATTTCAG AGGATAAAATTTTGTTAAAAAGAC TTCAATTTATTTTCACTGCTCTTTC AGATGGCAGAAATTACACGCGTA GATGCAGTTTGGCCAGGTTGGGGÇ ACATGCATCTGAGATCCCTGAGCT TCCAGATGCACTAACCGCAAAGG GGATTGAATTTCTAGGGCCTCCAG CTATATCTATGGCTGCTCTTGGAG ACAAAATCGGTTCATCATTGATTG CTCAGGCCGCAGATGTTCCAACT CTTCCATGGAGTGGCTCTCATGTA TGAATTGATTTTCTTATCGACCTTC ACAAACTTTCTTTTTCTCAAGGAG TTTCCTAATCAGTTTTCTTAAATTT CTATGCTTTAGGTGAAAGTTCCTG CTGAGAGTTGCCTTGATACTATTC CTGATGATATATACAAGGCAGCCT GTGTTTTTACCACAGAGGAAGCAG TTGCTAGTTGTCAGGTTGTCGGTT ATCCAGCTATGATTAAAGCATCTT GGGGTGGTEGGAGGGAAAGGAATA AGAAAGGTGAGCTAGTTGTTTGG GATGATGTCGTCAAGAAATTAAAG CACCGGCTTCATTGCTTATTTATC ACCCTTTTCACAGCTTCCATCCTT GGACATCCTTTTAATTAACTGTCC AGTAATATTTACTAGACTTAAATGA TGGACAAATGCTTCAAACTTGTTA GTTAGAGACCCGTTGTGCTATTTC AATTACAATTGTCTTTCTCTCAAAA TATCACAAAGACTCAATAGTTATG CATTTTCAGGTGCATAATGATGAT GAAGTAAGGGCATTGTTCAAGCAA GTGCAGGGCGAAGTTCCTGGCTC TCCCATATTTATAATGAAGGTGGC TTCACAGGTTAGTTATTCTGCAAA TTGGTGCTAGAATGTATCATTTAA GTACTCACAAGTCCATGGCACTCA TGATTTTAGAACTAGTACTGTACG CAAAATTCTTTGATTTTGACAAGTT ATTATATGTGCTTCAGAGTCGACA CTTAGAAGTGCAGTTAATTTGTGA TCAATATGGCAATGTAGCAGCTTT GCATAGCCGTGATTGCAGTGTCC AAAGGCGGCACCAGAAGGTGGGT CACTAGTGTACTATCAATAAATTTT TAATCTTCTTGACCAGTTTTGTATT ACTTAGGGTCTAAAGTTGTTITTITIT CATAGAGAATCGTGATGCTCATTG TTCATTGAAGGAATGTATAAATGA TCTTGTTCATTGTATTAATTGATCA GATTATTGAAGAGGGTCCAATAAA TGTAGCTCCCCAAGAAACTGTGAT AAAACTTGAGCAGGCAGCCAGAA GGTTAGCCAAATATGTGAATTTTG TTGGAGCAGCAACTGTAGAATATC TATACAGCATGGAAACTGGCGAG TTTTATTTCCTCGAGCTAAACCCT CGGCTACAGGTATGAAGCATACA CTTGCACATTGTATATTCATATTTA CCTCGAATAATTACTCAAGAAAGA AAATGTTTTATGTCAATATTTATGG CATTGCATCTCAATATCCTTTGGA TTTATCGTTTTCTACCTTACGTTTG TGGCTCACTTTAATATGACTTGCT TTTGTTAAGGAGCCTTGGGATTTC TTAGAGTGAGATATGACACTCTTG CCTTTCAACTTTTGTGAACCATGT CTGATACTCCCTCCATTTCCOTITTT GTTTGTTTGATTTATATCTTGAGG GGTGATATTATTCATAGGTAGAGA GATTCCTCTAAATTTATAAGATGA GACATAGCTCTGAGGGGTCTTGTT GAATTCATCTTGATGAGTACTTTA AATCAAAGCCTTGATGAGTACTTC AATAATATTAAATTTTTAGAATTTTT ATTCTTATATAGTTAAAGATACTAA CAACTAAAAATTTGCTCCAACAAA TGTGTGATAATGAATCGGGACAAA AGAAGGGAATGGAGGGAGTATTA CTAAGAATTAGCAATCCTATATGA TCATGTGATGGATGAAAAAAAAAA TTCTTATTTGACTTTTCTGACAATA TTGTATATAATGTCTGACATATGT GTAGGTTTTATTATATTTAATTTTA AAAAATTCCTGTTTGGAAAATCCG GTTAATTTTATTGGTTATTTATCTA ATTCCTTCTTTTGTTCGCGTTTGAT AAATACAGGTGGAGCACCCAGTA ACTGAATGGATTGCTGGAATTAAC CTTCCAGCTGCTCAGGTTGCAGTT GGCATGGGTATTCCCCTCTGGCA AATTCCAGGTAGCTAGCATGTTCC CTTTTTITATTATATAACTTATGTG CTTCATCTTGTTCTTGTGTATGAG TTGGCTTGCTTTTGCAATTTCAAA ATAGAAATTCGGCGATTCTATGGT AAGGAACATGGTGGCGGTTATGA TGCTTGGAGAAGAACATCAGTTGC AGCGACTCCTTTTGATTTTGACAA GGCACAATCTGTGAAACCAAAAG GTCACTGTACTGCCGTACGTGTG ACAAGTGAGGACCCTGATGATGG ATTCAAGCCCACTAGTGGGAAAGT ACAGGTTAATAATGCTATTGTTTTA TAGTTCAAACTATTTTCTCAATTGA TTGCCTTGTCTGTTTTGTGATTCAT GTAAAATTATTTAATTCATTGGTTT CTTTTCTAGGAGTTGAGTTTCAAA AGTAAACCAAATGTGTGGGCCTAT TTCTCTGTTAAGGTATGTCTTTATT TTTTTTAAGCTTTACATCATCCTTT TATGGATTCATCCACGAGCTTAAC AATGGTCAACACTGTCAATTGCAG TCTGGGGGAGGCATTCATGAATT CTCAGATTCTCAATTTGGTAAGTT TAAAGCACATTTTAAAGATGACTA GCAATGAAATGACTATTATAGCTG CCTTTTAAGAATGAAGTTCTTCAA CATCATAGTATTCATTCTCTAATTT AAGACTGCTGCAAATGGATTGAGA ACTGTGCTGTTGTGCATGTGAAAT GAGATATATTGGTTTTTCATAGTG TGTCATTGTAGACAGTAAATGCTC TTGTTAATTGTTGATGATTGGAATT GGGATTTAGCATGCTTGGTGTAGT TTTCTCTTGCACAAACAAGTCTCA TGGAATTAACATGTCATTTITTITA TCGATTATTTTTGGTTTTAAAACAT CCTTTATCTATTTTITTTTATITITITT TATAGAAGGCTAATGTTAGTTAAT TTGTTTGTAGGGCATGTCTTTGCA TTTGGTGAATCAAGAGGGTTGGC CATAGCAAACATGGTTCATGGCTT AAAAGAAATTCAAATTCATGGAGA AATTCGCACGAATGTTGATTATAC CATTGATCTTTTAAACGTGAGCCT TGTACATGATTTTTTTTCCTCCCTA CACTTTCCACTGTTTTTTCAATTAG AAGCTAAAGTTGTCTTTGTTITTTCC TTTCTCCAGTCTTCGGATTACAGA GATAATAAAATTCATACAGGTTGG TTAGATAGCAGAATTGCAATGAGA GTGAGAGCGGAAAGACCCCCCTG GTTCATCTCTGTTGTGGGAGGAG CACTCTACGTATGTACAGCTTTTT TTCTCTAAAATTTGTTTCCTTCCAA AAGCTTCATGTGTCACTTTCGTTT ATTTTTATAATGAATAATTTTAAAT ACTTCGTAATTTCTTTCTCCTTTCOT CCCTATCTTCAGAAAGCTTTTGCT AGTAGTACAGCTACAGTTTCAGAA TATGTTGGCTATCTTGAGAAAGGT CAAATTCCTCCAAAGGTAATTCAT GCACCAGACGCTGTTGAGGTATA CTGGTTTTTTTAAACACTAATTGTT TCTTTCAGTAAATTACATCAATATT TGTGTGGATTGCAGCATATATCAC TTGTCCACTCTGAAGTTTCTCTGA ATATTGAGGGGAGCAAGTACACT GTAAGTATATTATTATAACTGATGT GAATTTTATATTTCATTTTCGATTT CTTCTGTTTTCTTGTTAATCATCAT AACATGGTTGATGCTGTTCTCTAG ATCAAAGTGGTGAGGGGCGGTCCÇ AGGAAACTACAGATTGAGATTGAA TGAGTCTGAGATTGAGGCTGAAAT ACATCCATTAAGAGATGGGGGTCT TTTGATGCAAGTAAGAACTTAACT TTTATTCATTCATATATTCATGATT GAGGGCAATTGTCAAATTATACAC ATATAGGAGTGATAATATGTGTAG AGTTAAAATTGCGAGTGAAAGCTG AGATATTACTCTATGTATTTAGTAT ATCATTCACCATAGAATGCTTGAG TTACTTGCGTTAAATTAAAAAAAAA GGAAAGAGTAGAAATTAGAGAGT CTAATTTCTGTGGTCACAATGATA TGTCTAATTGAACGCACCCAATGT GTTTCAGTTATTTTTTTACCCCTAA CATAGGAGGGAAAACTGACTTAG CGGCTTCCCCTCTAGCATAGGATA TAAGTGCTCCAAACTCTTAGAATA TCTAAATTTGAAAAACTTATAATGT ATTATTGACATTCTTTCAGAGAAT GCTTTTCTGTGTGAACTCCTTAAG TATGTTAATAGCAATCCCGCAACC CTGTTTCACATTATATAGGTATTTG TTTCTTATTAGATGATATTCCATAT CTCCATATAAGATCTTTCTTCTTAC CAATTCAAGCCATATATTTITTGGA TTAAGAAGATGATATTCACAAAAG GTTTGCGTTATGATGATACTCAAT ATACCCACATGTTTCATATTTTCAT TGACTTAAACGCTATTTCTTAGAA AAGTTGGAGTTGTTGATCCAATGT ATGTGCTAGGTTCTCATCCCTTTG TTTTCAATTAGCTATGGATTTTGAG CTCTTCTGTACATTTGAATGTGAT GTAGTTGGATGGGAAAAGTCACG TGATATATGCTCAGGAAGAGGCA GCAGGAACTCGCCTTCTTATTGAT GGACGAACGTGTTTGCTTCAGGT ACCATCATGTTATTTAATTGCATAG TATTTCTAAACATTTACCAAGCGTA ACATGCTATTACATTTTCCACTTCT TCAATATTCAGAATGATCATGATC CTTCAAAGTTAATTGCGGAAACAC CTTGTAAGCTACTGCGGTATTTGG TTCCAGATGATAGTCATGTTGATC CAGATACTCCATTTGCTGAAGTTG AGGTTATGAAGATGTGTATGCCTT TGCTTTCCCCTGCATCTGGTAAAA TAAGATTTAAGATGTCCGAAGGAC AACCCATGCAGGTTAGCATAGGTT TTGGTAGATCTATATGTTAACTAAT TATACTTCAAAAGTTTCTTCTAAGT GAAGGTTCACTGTGTAGGCTGGC GAGCTCATAGCAAAACTTGAGTTG GATGATCCTTCAGCTGTAAGAAAA GCTGAACCGTTCCGTGGTAGTTTT CCAACCTTGCATCCGCCAACTGCT ATCTCAGAAAAGGTTCATCAAAAA TTTGTTGCAAGTTTGAATGCAGCC CAGATGATTCTTGCTGGTTTTGAA CACAACATAGATGAAGTAAGTATT TTAATAGTGAATTCAAAAATATTGA GCACTATATTATATAGATGAAGTA TTTCAGTTATGAATTAAACATAGAT GATGTAAGTATTACTCTAAGGGGG CTGATGCAAAAATTTGAGAGTAAA TGTATATTTATATTTTGTTTGGTTC CCTTATCTGAAAGATTCTTTACAAA AGAGTTTTCTAATTCTCAGGTTGT CCAGAGTTTGTTGAGGTGCCTTGA TAGTCCTGAACTTCCTTTCTTGCA ATGGCAAGAATGCTTGTCTGTTCT AGCAACACGGCTTCCCAAAGATCT GAGAACTGAAGTATGTTACTAAAA TCTGTATGCAATTTTTTTCCATATT TGATAAACACCTGCTGTCTTTAGC AGTCTTTATCTTCTTTGGTCOTTTCOT CCCTCTCTCTCTCTCTCTCTCACCO CTGTGTATAATTCACATTATTITITC CATGTTTCCCTGTCTTTGGTATTC TCAGTTGGAATCAAAGTGTCGAAA ATTCACAGGAATTACGAATTCTCA TAACATTGAATTTCCTGCTAAGCT GTTTAAAGGTGTTCTTGAGGTTAG TCTTTCTTTTTGTTACCCTTCTATA TATGCTATATATTTTAGTATTACTT ACATAAGTATTTTGTTTACAGGCC CATTTGAATTCATGCCCTGAAAAG GAGAGAGGAGCTCAAGAGCGGCT CATTGAACCTCTAATGAGTCTTGT TAAATCCTATGAAGGTGGGAGAG AGAGTCATGCCCATGTTATTGTTC AGTCTCTGTTTGAAGAGTATTTGA CTGTTGAAGAATTGTTCAGTGACA ATATCCAGGTTTGTTATTGCAGTT GCAAATTGATCAGTTTTITTGGTC AACCAATTTGTACCGGGACAAATT GCCACAGTCCTAATTTATTGATGA TCATCGGTCTTCGTGTTTITITCC CGGTTTGGTTGATTGGTTATCATG TTATGAAGTTGTCACATAAAAAAA CCTAAATTTACTAATGCACCCATTT GACCCTAGAGGCTACAGAGTCTTT GGAGTACTCTGTCTCTGTGGATTT ATAGTAGCATCCTTTGAAGTATTA CTTTATTTTTTCAAGAAATTGTAGT TCATGTCTTTTGATTCTGATCTTGA AAGGAAGGCTGACATCATTCCACT TTATTTTCTAATTTCAATCTATACA GGCTGATGTGATTGAACGTCTCC GCCTTCAACATAAAAAAGACCTGT TAAAGGTTGTTGACATTGTCCTAT CACATCAGGTAGGCAGGAAATTTC AAATAATACAAAATAAAATTTTCTG AGTTTTCTITITATITTOTTITCOITTT TTTTTCCCACTTTCCCTTGTACTGT CTTCTAGACTTGTTTACTGTGTAG TAATAATGGTTTTCAGGGTGTTAA GAATAAAAATAAATTGATCCTCCG GCTCATGGAACAACTGGTTTACTC AAATCCTGCCGCATATCGGGATAA GCTTAAACATTTTTCACAACTAAAC CATACAATCTACTCTGAGGTTAGT GATTATTCAATTTTTTGTTTATATT GTCACACTACAGCATTCACAAAAA GGTTATTAAGTTTATACACTAATCA ATTCCTTCACTATATGCAGTTGGC ACTTAAGGCAAGTCAATTGCTTGA ACAAACCAAGTTGAGTGAACTTCG TTCTAATATTGCCAGAAACCTTTC CGAGTTAGAAATGTTTACAGAAGA TGGTGAAAACATGGACACTCCAAA AAGGAAAAGTGCTATTAATGAGCG TATGGAGGCTCTTGTGAATACTCC GCTTGCTGTTGAAGATGCCCTTGT TGGCTTGTTCGATCACAGCGATCA TACGTTACAAAGGCGGGTTGTTGA GACTTATGTCCGGAGACTTTATCA AGTAATATCTAAGTTCCAACAGTA AACTTTAACTATCATTTAATAATGT TATGTCATATAACTCTATTTITIGT GGGTAATCTCTTTTCTCAGCCTTA TCTTGTAAAAGGAAGTGTCAGGAT GCAGTGGCACAGATCTGGCCTCA TTGTTTCTTGGGAGTTCATGGAGG AGCACATTGAAAGAGCAAATGCCT CTAATGATCTGTCCATCAACCAGC CCCTTGTTGAGAAACACAGTGAGA GAAAATGGGGAGCCATGGTCATC ATAAAATCTCTTCAGTTTTTGCCAA CAGTGATTACTGCTGCATTAAAAG AGACAACACATAATTCAGATGAAA CGATTCCCAGAGGCTCTTTAGAAT CAATCAGTCATGGAAATATGTTGC ACATTGCACTTGTGGGTGTTAATA ACCAGATGAGCTTGTTGCAGGATA GGTATAGATTCTATTTTTATGGTTT AAGCAAGATTTTAAAATGTGAACA TTGGACTATCCAATTTTATITTATGT TTATTTATTTATTTATTTTTTTGACG AGGACTATCCAGTTTTTTTGAAGA AATATGCTTTGCTTCAATTATGCA GTCGCTCTTTATAGTAACCATTCC GGCCTTTTGCTTAACCTTTITITCOT CTGTGGGGTTTATGAAATGGAATT TTATACTATGCAGTGGTGATGAAG ATCAAGCTCAAGAGAGAATTGATA AGTTGGCAAAAATCCTGAGAGAG AAAGAAGTGAGCTCAGGTCTTCGT GACGTTGGTGTCAGGGTAATTAGT TGCATTATACAGAGAGATGAAGGA AGAACGCCAATGAGGCATTCATTC TATTGGTCAGAAGAGAAACAATAC TTCAATGAAGAGCCTTTACTACGT CATTTGGAACCTCCTCTATCAATA TATCTTGAACTGGTAATAAAATTCT GAGCAAGAAGCTGTTGCTTTGTTT GTTCGTTCTTTTCTTGTTTTTTAAT ATGGGCCAAATCATTATCTTTAAT ATTTTTATCACTATATGATATAGTT ATAAGGTATTTGGCTCACAATTTT CATTATACAGGACAAGCTCAAACA CTATGAAAATCCCAGATATACTCC TTCTCGGGATCATCAGTGGCACCT GTATACTGTCATGGACAAGCCATC TATTCGACGAATGTTTTTGAGGAC ACTTGTCAGACAGCCCACCTCCG AGTTTAGCGGGGTTGAACTAGAAA TGCTTAAAACACAAAGGCCTATCT CCTTTACTTCAAGAAACATACTGA GGTCTTTAACAACTGCAATGGAAG AATTAGAACTCAATGCGCACAATG CTACCTTGAAACCTGATCATGCTC ATATGTACCTGTGCATTGTAAGAG AGCAACGAATTCAAGATCTTGTCC CATATCACAGGTTCTAATTAATCAT CTTAATTTTCTGTGTTTCATTCGTG GTCATTGATGCAACTTATGCCTTA ATAGATATTATTTTGACCCATTGAT CCAGGGAGGTGAACATTGATGAT GAACAAGAAGAGATAACTGTTCAG ATATATTTGGAAGAGCTTGCGCGT GAAATCCACAGTTTTGCTGGTGTG AGAATGCATAAACTAAATGTATGT GAGTGGGAAGTAAAGCTTTGGGT GTCATCTTCTGGCCAAGCCAATG GTTCATGGAGAATCATTGTTAATA ATGTGACTGGTCATACATGCACTG TACATGTAAGTTTGAACTATGATA ATTTTTTCCTATAATTTTCTGTAAA GGTTTTTAGTATTGGCCGTGTTTA GTAATTTCTTTCAACACTCAGATAT TTATGCCAGTTTTTGTAAGAATTAT AGAAATACAGTAGCAATGTTTTGA TAGCCCAGGTTCTCTCTTTCTCCC AAATTAATCTTTGTGTCAATGCAT GACTTTGCCGCATCAATATCTTAA ATAATTTATGATTATAAACTATAAG AATATGATACTATGAGAAATTGAA AATATACATCGAGAGAAATCTAAA TACATCTTCCATTACAACCTTTGAT TTTITTITITITITITITAAATTGAAAA AACAATGGGTAAAGGTGATACATG AATCTTGTAAAACACAAACAATGA CCATACATATGGGACGGAGGGAG TAATAATGGTTTGTATATTGGCAC TTATAAAGAAAAAGGTTATGCACA ATTAATTTATGTCTTGTAGACGTGT ATCACATAATGTCTTCTTTAGTTTG CTGACCTTTTTTCTACTAATGTTAT GCAGGTTTACCGTGAGTTGGAGG ATAACAACCTTCATGAAATGATCT ACCATTCAATATCTGTTCAAGGTC CTCTCCATGGAATACCAGTGAATG CACCCTATCAACCACTTGGAGTCA TTGCCCGTAAAAGACTTCAGGCCA GGAAAAATAGCACAACCTATTGTT ATGACTTCCCACTGGTAAGAAATA TTAAACTCCACTATACCCCAATAC TACAAAAGCAGAATTTTACTATATT AGGTTTCCTTCCCTCCCGAATTTT TTTAAAAAATAAGAGTTAATACATG ACTTGCATTCGAGTGTAACTATGG TTCTTGTTTACGCTCAACTAGTAAT GAAATAGGAATATAAATCTAATAA AGATTTACAAATTTTGGAGAGAGG CGGGGTTGTGTAACTGTGGGACT TTGTAAAGGTTTAAAGTTAGTTAG GTGGAGATGCAGGGTTTATATTTA GTTTATGAGGAAACTACAAGTTTT CAAGATTTTAATAGGTAATACGTG TAAAATTTTAAAAGATATCGGAATA TTTGTCTTAGTATTTTGGATTATTG TAACTTTGTAAATAAAAATAGTTTC ACATTTTGTTAAGATTTCAAGTTTG GCTTTCGCACACAATGGGTCTGTT CTTTTCACCTTATCTGTACTTATCC GAACTTTTCCGAACTTCTATGAAC
TTGTTTTGTGAGAGAGAAAA 78 Kochia gD- 10030 | ATGTCTTTGCATTTGGTGAATCAA scoparia |NA- GAGGGTTGGCCATAGCAAATATG Con- GTTCTTGGCTTGAAAGAAATTCAA tig ATTCGTGGAGAAATTCGCACTAAT
GTTGATTATACCATTGATCTTTTAA ACGTGAGCCTTATACATGAATTTC CCCCCTACACTGTTCACTGTTTIT TCAATTAGAAGCTAAACTTGTCTTT GTTTTTCCTTTCTCCAGTCTTCGG ATTACAGAGATAATAAAATTCACA CAGGTTGGTTAGATAGCAGAATTG CAATGAGAGTCAGAGCGGAAAGG CCCCCCTGGTTCATCTCTGTGGT GGGAGGTGCACTCTACGTATGTA CAACTTTTCTCTTAAATTTTCITTCC TTCCTCAAGCTTCATGTGTCACTT TCGTTTATTTTTATAATGAATAATT TTAAATGATTCTTTCTCCTTTCTCC CTATCTTCAGAAAGCTTCTGCTAG TAGTGCGGCTACTGTTTCAGAATA TATTGGCTATCTTGAGAAAGGTCA AATTCCTCCAAAGGTAATCCAAAT ACCAGATGCTGTTGAGATATACTT GTTTTTTAAACACTAATTGTTTCTT TCAGTAAATTACATCAACATTTGT GTGGATTGCAGCATATATCACTTG TCCACTCGGAAGTTACTTTGAATA TTGAGGGGAGCAAGTACACTGTA AGTTTATTATTAACTGATGTGAATT TTATTTTTCGTTCATGGTTTCTCCT GTTTACTTGTTGTTAATCATCATAA CATGGTTGATTCTGTTCTCCAGAT CAAAATGGTGAGGGGCGGTCCAG GAAGCTACAGATTGAGATTGAACG AGTCAGAGATTGAGGCAGAAATA CATACATTAAGAGATGGGGGTCTT TTGATGCAAGTAAGAACTTAATTTT ATTGATTCATATATTCATGATTGAG GACAATTATAAACCTCAAGCTATA CGCATAGGAATTATAATTTGTATA GAGAGTTAAAATTGCGAGTGAAAG CTAAGATATTGCACCAACATGTAT TAAGTCTATCATCCACCACATAAT GCTGAAGTTACCTCCGTTAATTAA ATTTAAAAAACAGGAGAGTGTAGA AATTAGATAGTCTAAGTTTCTGTA GTCATAATGATATGTCTTTTGGAA AGTGCCCCAATGTGTTACATTTAT CTTTTACCCCTAACTTAGTTTAGG AGGGAAAGCTGACTTAGCAACTTC TCCTCTAGTACAGGATATAAATGC TCAAAACTCTTAGAATATCTAAATT TGAAAAGATTATAATGTATTATTGA CATTGTTTCAGAGAATGATTTTCT GTATGAACTCCTTAAGTATGTTTTT TGACAACTCCTTAAGTATGTTAAT AGCAATGCCACAACCCTGTTCCAC ATTAGGTAGGTATATATGTTTCTG ATTAGAAATTATATTCCATATCTCC GTATAAGATCTTCCTTCTTACCAA CACGAGCCATATAATTTTGGGATT AAGTAGATGATGTTGGTTTGCATT ATGATGATACTTAATATACCCACA TGTTTCATATTTTCATTGACTTAAA CGCTATCTTCTAGAAAAGGGGTAG TTGTTGATCCAATGTATGTGCTAC ATTCTCATCCCTTTGATTTCAACTA GCTATGGATTTTGAGCTATTCTGT GCATTTGAATGTGATGCAGTTGGA TGGGAACAGTCATGTGATATATGC TGAGGAAGAGGCAGCAGGAACTC GCCTTCTTATTGATGGACGAACAT GTTTGCTTCAGGTACCATCTTGTT ATTTAATTGCATAATATTTCTAAAT CTTTACCAAGCGTAACCTAGTATT AAATATCCCCCTTCTTTGTATCCA GAATGATCATGATCCTTCAAAGTT AATTGCGGAAACACCTTGTAAGCT GATGCGGTATTTGGTCCCAGATAA TAGTCACATTGATCCAGATACTCC ATTTGCTGAAGTTGAGGTTATGAA GATGTGTATGCCTTTGCTTTCCCC TGCATCTGGTAAAATACAATTTAA GATGTCCGAAGGACAAGCCATGC AGGTTAGCATAGGTTTTGGAAAAT CTATATGTTAACTAATTATACTCTA AAAGTTTTTTCTAAGTGCGTGTTC GCTGTGTAGGCTGGCGAGCTCAT AGCAAGACTTGAGTTGGATGATCC TTCAGCTGTAAGAAAAGCTGAACC TTTCCGTGGCAGTTTTCCAATTIT GGGCCCCCCAACTGCTATCTCAG GAAAAGTTCATCAAAGATGTGTTG CAAGTTTGAATGCAGCCCAGATGA TTCTTGCTGGTTATGAACACAACA TAGATGAAGTAAGTATTTCAATAG TGAATTCAAAAAATCGAGCAATAT ATTATATACATGAAGTATTCCTATT ATGAATTTAACATAGATGATGTAA GTATTCCTCTGAGGGGCTGATGC AAAAATTTGAGATGTATATGTATGT CTATTTATATTTTGGTTGGTTCCCT TATCAGAAAGATTCTTTACAAATG AGTTTTCTAATTCTCAGGTTGTCC AGAGTTTGCTGATTTGCCTTGATA GTCCTGAACTTCCTTTCCTGCAAT GGCAAGAATGCTTGTCTGTTCTAG CAACACGGCTTCCCAAAGATCTGA GAACTGAAGTATGCTACTAAGTTC TGCATGCAATTCTTTTTCTATATTT GATAAACACCTGTTGTCTTTAGCA GTCTTTATCTTCTITITTCOITICTIT CTTTTTCTCTGTAACTCACATTATT TTACCATGTTTCCTTATCTTTGGTT TTATCAGTTGGAGTCAAAATATGG AAAATTCGAAGGAGTTACCAATTC TCAGAACATTGAATTTCCTGCTAA GCTGTTTAAAGGTGTTCTTGAGGT CAGTCTTTCTTTTTGTTACCCTTCOT GTATATGATACAGTTTGAGTGTTA CTTACATAAGTATTTTGTTTACAGG CTCATTTGAATTCATGCCCTGAAA AGGAGAGAGGAGCTCAAGAGCGG CTCATTGAACCTCTAATGAGTCTT GTTAAATCCTATGAAGGTGGGAGA GAGAGTCATGCCCATGTTATTGTT CAGTCTCTGTTTGAAGAGTATTTG ACTGTTGAAGAATTGTTCAGTGAC AATATCCAGGTTTGTTATTGCAGT TGCAAATTGATCAGTTTTITTGGT CAACCAATTTGTACCGGGACAAAT TGCCACAGTCCTAATTTATTGATG ATCATCGGTCTTCGTGTTTITTITC CCGGTTTGGTTGATTGGTTATCAT GTTATGAAGTTGTCACATAAAAAA ACCTAAATTTACTAATGCACCCAT TTGACCCTAGAGGCTACAGAGTCT TTGGAGTACTCTGTCTCTGTGGAT TTATAGTAGCATCCTTTGAAGTATT ACTTTATTTTTTCAAGAAATTGTAG TTCATGTCTTTTGATTCTGATCTTG AAAGGAAGGCTGACATCATTCCAC TTTATTTTCTAATTTCAATCTATAC AGGCTGATGTGATTGAACGTCTCC GCCTTCAACATAAAAAAGACCTGT TAAAGGTTGTTGACATTGTCCTAT CACATCAGGTAGGCAGGAAATTTC AAATAATTCAAATTAAGTTTGAGTT TTCTTTTCCCTTTTCCCTTGTAATA TCTTCCAGGCTTGTTTACTATGTA GTAATAATGGCTTTCAGGGTGTTA AGAACAAAAATAAATTGATTCTCC GGCTCATGGAACAACTGGTTTACC CAAATCCTGCCGCATACCGGGAG AAGCTTATCCGTTTTTCACAACTA AACCATACAATCTACTCTGAGGTT AGTGATTATTCAATTTTITTGTITTAT ATTGTCACACTACAGCATTCACAA AAAGGTTATTAAGTTTATACACTAA TCAATTCCTTCACTATATGCAGTT GGCACTTAAGGCAAGTCAATTGCT TGAACAAACCAAGTTGAGTGAACT TCGTTCTAATATTGCCAGAAACCT TTCCGAGTTAGAAATGTTTACAGA AGATGGTGAAAACATGGACACTC CAAAAAGGAAAAGTGCTATTAATG AGCGTATGGAGGCTCTTGTGAATA CTCCGCTTGCTGTTGAAGATGCC CTTGTTGGCTTGTTCGATCACAGC GATCATACGTTACAAAGGCGGGTT GTTGAGACTTATGTCCGGAGACTT TATCAAGTAATATCTAAGTTCCAA CAGTAAACTTTAACTATCATTTAAT AATGTTATGTCATATAACTCTATTT TTTGTGGGTAATCTCTTTTCTCAG CCTTATCTTGTAMAAGGAAGTGTC AGGATGCAGTGGCACAGATCTGG CCTCATTGTTTCTTGGGAGTTCAT GGAGGAGCACATTGAAAGAGCAA ATGCCTCTAATGATCTGTCCATCA ACCAGCCCCTTGTTGAGAAACACA GTGAGAGAAAATGGGGAGCCATG GTCATCATAAAATCTCTTCAGTTTT TGCCAACAGTGATTACTGCTGCAT TAAAAGAGACAACACATAATTCAG ATGAAACGATTCCCAGAGGCTCTT TAGAATCAATCAGTCATGGAAATA TGTTGCACATTGCACTTGTGGGTG TTAATAACCAGATGAGCTTGTTGC AGGATAGGTATAGATTCTATTTTTA TGGTTTAAGCAAGATTTTAAAATG TGAACATTGGACTATCCAATTTTAT TTATGTTTATTTATTTATTTATITTTT TTGACGAGGACTATCCAGTTTTTT TGAAGAAATATGCTTTGCTTCAAT TATGCAGTCGCTCTTTATAGTAAC CATTCCGGCCTTTTGCTTAACCOTT TTTITCTCTGTGGGGTTTATGAAA TGGAATTTTATACTATGCAGTGGT GATGAAGATCAAGCTCAAGAGAG AATTGATAAGTTGGCAAAAATCCT GAGAGAGAAAGAAGTGAGCTCAG GTCTTCGTGACGTTGGTGTCAGG GTAATTAGTTGCATTATACAGAGA GATGAAGGAAGAACGCCAATGAG GCATTCATTCTATTGGTCAGAAGA GAAACAATACTTCAATGAAGAGCC TTTACTACGTCATTTGGAACCTCC TCTATCAATATATCTTGAATTGGTA TGATATTCTGAGCAAGAAGCTGTT TCTTGTTTATTATTTTCOTTGITTTCOTT AATATGGGTCAAATCATTATCTTTA ACATTTTTGTCACTATTTGATATAG TTATAAGGTATTTGGCTCACAACT TTCCTTACACAGGACAAGCTCAAG GTCTATGAAAATCCCAAATATACT CCTTCTCGGGATEGTCAATGGCA CCTGTATACTGTCATGGACAAGCC ATCTATTCGACGAATGTTTTTGAG GACACTTGTCAGACAGCCCACTTC CGAGTTCAGTGGGGTTGAACTAA AAATTCTTCAAACACAAAGGCCCA TCTCCTTTACTTCAAGAAGCATTC TGAGGTCTTTAACAACTGCAATGG AAGAATTAGAACTCAATGCGCACA ATGCTACCTTGAAACCTGATCATG CTAATATGTACCTGTACATTGTAA GAGAGCAACAAATACATGATCTTG TCCCATATCACAGGTTCTAATTAC TATTCTTAATTITATGTGTCTCATT TGTGGTTATTGATGCAACTTATGC TTTAAGAGGGATTATTTTGATCCG TTAATCCAGGGAGGTGAACATTGA TGACGAACAAGAAGAGACAGCTG TTCATATGTACTTGGAAGAGCTTG CGCTTGAAATCCACAGTTGTGCTG GTGTGAGAATGCATAAACTAAATG TATGTGAGTGGGAAGTAAAACTTT GGATATCATCTTCTGGTCAAGCCA ATGGTTCATGGAGAATCATTGTTA CTAATGTGACTGGTCATACATGCA CTGTACATGTAAGTTTGAACTATG ATAATTTTTTCCTATAATTITCTGT AAAGGTTTTTAGTATTGGCCGTGT TTAGTAATTTCTTTCAACACTCAGA TATTTATGCCAGTTTTTGTAAGAAT TACAGAAATAGTAGCATGTTTTTA GTGCCCAAGTTCTTTCTITTGTCCOT TTTGCCCAGCAATATCTTTAATAAT TTATGTATAAACTATAAGATATTAT GAGACTATACATCGAGAAAAATCT AAATACATCTTCCATTACAACCTTT GATTTTITTTTITITTTTITTTAAATTGA AAAAACAATGGGTAAAGGTGATAC ATGAATCTTGTAAAACACAAACAA TGACCATACATATGGGACGGAGG GAGTAATAATGGTTTGTATATTGG CACTTATAAAGAAAAAGGTTATGC ACAATTAATTTATGTCTTGTAGAC GTGTATCACATAATGTCTTCTITA GTTTGCTGACCTTTTTCTACTAAT GTTATGCAGGTTTACCGTGAGTTG GAGGATAACAACCTTCATGAAATG ATCTACCATTCAGTATCTGTTCAA GGTCCTCTTCATGGAATACCAGTG AATGCACCCTATCAACCACTTGGA GTCATTGCTCGTAAAAGACTGCAG GCCATGAAAAACAGCACAACCTAT TGTTATGATTTCCCACTGGTAAGA GATATCAAACTCCACTGTACCACA ATACTACAAAAGCAGAATTTACAG TATTAGGTTTCCTTTCCTCCAAAAA AATCAAGGGTTGATGCATGACTTA CATTCGAGTGTAACTATGGTTCTT GTTTACGCTCAACTAGTAATGAAA TAGGAATATAAATCTAATAAAGATT TACAAATTTTGGAGAGAGGCGGG GTTGTGTAACTGTGGGACTTTGTA AAGGTTTAAAGTTAGTTAGGTGGA GATGCAGGGTTTATATTTAGTTTA TGAGGAAACTACAAGTTTTCAAGA TTTTAATAGGTAATACGTGTAAAAT TTTAAAAGATATCGGAATATTTGTC TTAGTATTTTGGATTATTGTAACTT TGTAAATAAAAATAGTTTCACATTT TGTTAAGATTTCAAGTTTGGCTTT CGCACACAATGGGTCTGTTCTTIT CACCTTATCTGTACTTATCCGAAC TTTTCCGAACTTCTATGAACTTGTT TTGTGAGAGAGAAAAATAATAAGT TTGTTCTTTTCAACTTATTTITTTATT ATCTGAACTTATTTGAATTTATTIT TTCTGAAATTAAGTAAAAATAAGCT CAATAGAACATACCCAATGTAGAA AAATAGAATTAAACAAAGAAATAG TGGGGAAAAAAAGTGGAGGTGAT TTGTGTCTCTTGTGGGCATTAGTT TAGTAACAGCTAGAGTAATGGATA TAGATGACTTATTTTTAATTCATTG TATGACATACATCAAAAACCTGAA ATTTTAGTGATATCAAATTGGCCTT AATTAGTAATTTAGTTGTTTGATAT TGTTGGTTATACAAGTGAAAACAG ATACTTAATATGCGAATGATTGTG CCTATAGTGATTATGTGACTGTGT TGTTAAATATAAAAGTGTTTCAGT GTTTTTAAGACAAGGGAAGTAGG GAACCATAAACAAAAATACGAAGC ATATCTTGGGTGTTACCTAGTTTT GTCCTATTTCTCAATTATTGATTTA GTTGTTTAATTTGTTGGTTATAAAA GAGAGAAACCGGGATTGTTGGTG TGCAAAGATTGTACCTATAGTGAT TATGTGACAACGTTGTCAAATGTA AAAGCATTGCAATTTTTGTGAGGC AAAGGAACCATAAATAAAAATGCG AAGCATGGCTTGGGTGTTACCTA GCTTTGTCCTATTTATTGAACTATG TGATTGTACCTCAAATTTTTATATT TGATGTTGTATCGATCAACTTGCT TTAGCTCACGTTAGCATTTATCTG TTTTTCTATTGGAAAATTGACCTGA AATTATTGGGAATGTTTTTCTCAG GCTTTCTCTACTGCCTTAGAGCAA TCATGGGCATCTCAAGCTCCGCTT CTGAAGAAACCCGCTAACAAAAAA GTTTTGAAAGTCTCAGAGCTAGTA TTTGCTGATTCAAATGGCACCTGG GGAACACCAGTTGTCCCGACAAA TCGTGAACCTGGTCTTAACAATAT TGGCATGGTTGCCTGGTCCATGG AGATGTCAACTCCTGAATTCCCTG ATGGAAGAACCATATTGGTTGTAG CAAATGATATCACCTTCATGGCTG GATCATTTGGGCCAAAAGAAGATG CTCTCTTCCAGGCAGTTACAGATC TTGCTTGTTCCAAAAAAATTCCTCT GATTTACCTGGCTGCTAATTCTGG TGCTCGACTGGGTGTTGCTGAAG AGGTAAGAGCATGCTTTAAAATTG GTTGGACCGATGAGTTGAACCCT GAGCGGGGGTTCCAGTATATCTA CTTGACTCCTGAAGATTATGAGCG TATAGGGTCAGCAGTTATAGCCCA TGAGTTAGAACTCCAAAATGGAGA GACTCGGTGGGTTATAGACACTG TTGTAGGGAAGGAGGATGGGATA GGTGTTGAGAACTTATCTGGAAGT GGAGCTATAGCTGGTGCCTACTC AAGGGCATACAAAGAAACTTTTAC TCTAACTTTTGTAACAGGAAGAAC AGTAGGTATTGGTGCCTATCTTGC TCGCCTTGGGATGCGTTGTATCCA AAGGCTTGATCAGCCCATTATTCT GACAGGCTTTTCTACGTTAAATAA ACTTCTTGGTCGTGAGGTTTACAG CTCACAAATGCAACTTGGCGGGC CCAAGATTATGGGTACAAATGGTG TTGTTCATTTAACAGTTTCAGATGA CCTTGAAGGCATTTCAGCTATTGT CAAGTGGCTCAGCTATGTTCCATC CTACTCAGGAGGTGAACTTCCTAT TTCACGTTCTTTAGATCCTCCTGA AAGACAGGTTGATTATTTGCCTGA AAATTCTTGTGATCCCCGTTCTGC TATATCTGGTACACTTGACTCTAA TGGCAATTGGCTTGGTGGAATTTT TGACAAAGATAGTTTTGTTGAAAC CCTAGAAGGCTGGGCAAGGACAG TTATCACTGGCCGGGCCAAACTT GGTGGAATCCCAGTTGGGATAGT TGCTGTTGAGACACAAACTGTGAT GCAAGTTATCCCAGCAGATCCTG GTCAGCTTGATTCGCATGAGCGA GTGGTCCCACAAGCTGGACAAGT ATGGTTTCCAGATTCTGCAACTAA GACAGCACAAGCTTTGATGGATTT TAACAGGGAAGAACTTCCACTTTT CATTCTAGCTAACTGGAGAGGCTT CTCTGGAGGGCAAAGGGATCTCT TTGAAGGGATTCTTCAGGCAGGG TCCACAATTGTCGAGAACCTTAGG ACTTATAATCAACCTGTTTITGTTT ATATCCCCATGATGGGTGAACTTC GTGGTGGGGCATGGGTTGTCGTA GACAGTAAAATCAATTCGGACCAT ATTGAGATGTATGCTGATCAGACA GCTAAAGGAAATGTTCTTGAGCCA GAAGGAACGATTGAGATCAAGTTT AGAAACAAGGAATTAATTGAATGT ATGGAAAGGCTTGATCAACATCTC ATCAATCTTAACGCAAAACTCGTC GAAGCCAAAAACTCCAATTTATAT GTTAATATCGAACTCCTGAAACAG CAGATAGAAGCTCGGCAGAAGCA ACTTTTGCCTCTATATACTCAAATA GCCACAAAATTTGCTGAATTGCAT GATAGTCCTTATAGAATGGCTGCG AAAGGAGTCGTCAAGGAAGTCCT GGATTGGAGCAATTCTCGCTTATT CTTCCACAAAAGACTGTACAGGAG AGTTATGGAGGAATCACTTGTCAA GACCGTCCGAGATGCTGCTGGTGE AAGCAATGACCCACAAGTCTGCC ATGGAATTGATCAAGCAATGGTTT GCTCAGTCTGATAGTACTAGTGGA GTGGGAGCTGATCCTTGGTCTGA TGATGAAGCTTTCTTCAAGTGGAA AGAAAATCCTGCTAATTATGAAGA AAAGCTAATTGAGTTACGCATACA GAAAGTATTGCATCAGCTTTCAAA TATTGACAACTCAGCTTCTGATCT GAGAGCTCTTCAGCTTCGTCAGG GTCTTGTTGCCCTACTTCAGAAGG TATCTCTAAGGTTCCTCCACACAC ACACACACCCCACCCACCAAAAAA
AACACACAACACAACAGTGAG 79 Kochia gD- 8717 GATCTTGATTGATGTTGAGGATGA scoparia | NA- CTTGTTCTGACGTTGTTTTCTTGAT Con- GATCGGCCTGTAAAATGAAACAAA tig GATTGCTACCTCGGAGGTTTTCCC
GAGTAAAACCTCTCCGAAGTTTAA GTCAGTTCAATGATCTTGAATGGA TTGGTATTTTAGGAATTTAATGTGA GTCGTTTTAGAATTAGATACCTGA TTTTGTGTGGAGAGCTTGGTATAT ATAGGCAATCGGGTGACCTACTA GCTTATCAGTCAAGCGATGTAATC CGGCACCTGGTAGCTTGTCATCA GTTTGACTGGGCAATTAATGGTCA AGCGGTTTGAAATGTGTTTCTTGG ACCTTAAATATGGCTTTGGTTATA ATGAGCTAGATTTAGGTTTGGACC TTAGTTTTATGGGTTAATACTAGA GGCGATCAAAAAAACCCGGCCCG ACCCAAAATTTTGTGGGCTTTGGT CACGACTTTTTTTTGGCCCGAATA CCCATACACAAACTAAAATGGCTA GTACAAAAGTACAAATATACAAAA GTTGTTCTTACTAGAAAAAGCTAG TTATTGACCATCAATTATCTCAAGT CCAAATAAACTTTTATAAGCACTA GAAGTAAGTTGTATGAGAAGTATT GATCAATAACTCAGCAAAATAGTA CTTCGTATATAATTATAAACAAGAA GTCAAATTTGGTGGAGTGTGATTG AATTGAAAAAATTGGTAGAATTCA ATATGATACAACAAAGAAAAGCTA CATGGTCATATTAAAAGTTAAATTT TGCATAACAAGAGTAAAAGAAATG ATAAATTGATTGACACGATCAATA AATCACCGGATAAATTCGTCATTT CTTATTATCAGTCCTTCAAATTATA ATAAATTCCCCAATCCCCCACCTA CCATTATACTCGTAAGTTTTTAACA ATGCTGGAACAAACAGTGCAAATG TGTGATTTAAAAATCGGTGCTATT TGTTTATACTTCCTCGTTGCAGTA GCATCATCACACATTCATACTAAA ATCAAAATCACATTCATCATAAATC ATAATAATAAATAATAGAATAATTA TACAGGTAGCTGAAAGGTGGGCA GTTGCCACGTGCATCCCCAAATAA ATATGCAGTTAATTGAATGAGATG GAATGGAAGGCATTCTCTGCACCT CAAACCAAACCAACCCCCTTCTTC CCCTCTAACACTTCTTCAATGACT TCTCTTCCTTCTTCTTATTCTCATT ATATATACATTCACAAGTAGCTGA TCACTACTGTTITTCITTITITITIGITT CTGTCTAAAGTTTGATTCTTTTCCA TCAAAGTTTGCTTTTTTATGCAATA ATTCAAATTGCCCAGATGCTAATT TAGTGGAATTTCATTGAAAGGTTT GTTTTTTTCTGCTGAATTATGTCCC TTTGATTTGATTTGAGTGTTTTITA AGTTTATGATGAATCATACATGCC CTTTTATTTGAGTTGATTTTGGGAT TTGTCTTATGTTGGGGTTGGTTTT TGGTTGGTTTTTGGTTGGTTTTTIT TGGTAGTGTGTAGTTGAGCTAATT AAGTGTAGAATAGTGTGAAATAAT ATATTGGTTGTATTGGGTATTGCT TACTAGAAAATGTGATTCATTTTG GTAGTTAGTTGGCTTTAGTTGACT GACTCTTCTAAGTTCTAACTATGA TTGATTGATTGATAATACAGGTAT GTGTAGTCCAAATTGGACCTCATT TTATAATTATCCTCATTTTATAATT ATAATTTGTTTTTTTITGGCATTGGA TTGTTGACTCTTGAATTCTACTTCA CTACTTGAATTGCATTGGATTTITTT CTATTAGTATTTAGCTTTTATGCCA TAATAAAAACTTCTGCCTTTCATTC AGCTGGTATGTTCTATACTTCTATT CTTTTTITTTTTTTATATAAATTAAT TCTTTCTTITCTCTGTTAATGTTGTT GTTGTGTTGGATAATATGTTAATTA CCCAATTAAAGAGCTCAAATCTTG AAGTAATGTATGAGTATTGCTTAT GATAGTAGCTTTTGTGATTCAAAG CTTGCATCATTCATTAATTGACTAT TTGTTTTGTGTAATACGAGGTTGT TGTAGCTTGATTGCTTTTTGACAG GTAGAATATGCTTATCATGTGAAA ATTGGGAATGTTATTCATGTGATT TGATGTTATTAGGATGCTGACCAG TGTTTTATGAGGTGATACTGATTC AACTTGTTGATGTAACAGTTATAG GAAAATCGGGCGTATTTTTTGCTG AGGGCGGGGCGGTEGTGTTAACTA GGGAAGAGCCAAAGATGGCAACT CTAGTGCGAAACATTGATTACCTT AATGGAACAACTCTGTTGAGGAAT TCTACTACATTACCCGTTGTTGAT GAATTTTGTTATGCTCTTGGAGGG AAAAAGCCGATTCATAGTATTTTG ATTGCCAACAATGGAATGGCAGCT GTTAAATTTATCAGAAGTGTTCGG ACATGGGCTTACGAAACTTTTGGA ACAGAGAAGGCTATTGTATTAGTA GCAATGGCTACTCCAGAAGACAT GAGAATCAACGCTGAACACATTCG AATGGCTGACCAGTTTGTTGAGGT TCCTGGTGGGACTAACAACAACAA CTATGCCAATGTACAGCTCATTGT TGAGGTAAATCCTGCTTTAGTAAC ACTGATCTTCCGTGTTTTCTCTGT TAGATTACGAAATACTCACATTAG CCACAGTGTATGAGAAAAGATATC ACCTGTCCTGTTGGCCTGTTGATG TTCATCATTGATTTCAGAGGATAA AATTTTGTTAAAAAGACTTCAATTT ATTTTCACTGCTCTTTCAGATGGC AGAAATTACACGCGTAGATGCAGT TTGGCCAGGTTGGGGACATGCAT CTGAGATCCCTGAGCTTCCAGAT GCACTAACCGCAAAGGGGATTGA ATTTCTAGGGCCTCCAGCTATATC TATGGCTGCTCTTGGAGACAAAAT CGGTTCATCATTGATTGCTCAGGC CGCAGATGTTCCAACTCTTCCATG GAGTGGCTCTCATGTATGAATTGA TTTTCTTATCGACCTTCACAAACTT TCTTTTTCTCAAGGAGTTTCCTAAT CAGTTTTCTTAAATTTCTATGCTTT AGGTGAAAGTTCCTGCTGAGAGTT GCCTTGATACTATTCCTGATGATA TATACAAGGCAGCCTGTGTTTTTA CCACAGAGGAAGCAATTGCTAGTT GTCAGGTTGTCGGTTATCCAGCTA TGATTAAAGCATCTTGGGGTGGTG GTGGGAAAGGAATAAGAAAGGTG AGCTAGTTGTTTGGGATAATGTGG TCAAGAAATTAAAGCACCATCTTC ATATATATCTCTATTGCTTATTTAT CAACATTTTCACAGCTTCCATCCT TGAACATCCTTTAATTAGTCAATTG TCTATAATTATCTACTAGTCTTAAA TGATGGACAAATGCTTCAAACTTG TTAGTTAGCTAGAGACCTGTTAAT CTGTTATGCTACTTCAATTTCAATC GTTTTCCTTTCAAAATATCAGAAA GACTCAATAGTTATGCATTTTTAG GTACATAATGATGATGAAGTAAGG GCATTGTTCAAGCAAGTGCAGGG CGAAGTTCCTGGCTCACCCATATT TATAATGAAGGTGGCTTCACAGGT TAGATATTCTGCAAATTGGTTCTAT AATGAATTATATAAGCACTCAGAA GTTCACGGCACTCGTGATCTTAGA ACTTGTACTATATGCAAAATTCTTT GTTTTGACAAGTTGTTATATGTGC TTCATTCAGAGTCGACACTTGGAA GTACATCTACTTTGTGATCAATAT GGCAATGTAGCAGCTTTGCATAG CCGTGATTGCAGTGTCCAAAGGC GGCACCAGAAGGTGGGTCCCTAG TGTACTATCAATAAACTTTTAATCT TCTTGACCAATTTAGTATTACTTCG GGTCTAAAGTATATTTTTTCAAAGA AAATCGTTATGTCTCATTGTTITTTG AAGGAATGTATAAATATTTTGTCC ATTGTATTAATTGATCAGATTATTG AAGAGGGTCCAATAACTGTAGCTC CACCAGAAACTGTGAGAAAACTTG AGCAGGCAGCTAGAAGGTTAGCC AAATGTGTGAATTATGTTGGAGCA GCAACTGTAGAATATCTGTTCAGC ATGGAAACTGGCGAGTTTTATTTC CTTGAGCTAAACCCTCGGCTACA GGTTTGAAGAATACACTTGCACAT TGTATATTCGTATTTTCCTTAAGAA AAATATTTTATGTTGATATTTATGG TATTGCAACTCAATATCCTCTAGA TATATCGTTTTCTACCGTACGTTT GTGGCTCACTTTATTATGACATGC TTTGTTAAAAAGCCTTGGGATTTC TTAGAGTGAGACATGTCACCCTTG CTTTTCAACTTCTGTGAATCATGT CTTATACTCCCTCCATTTCCOTTITTG TTTGTCTGATTTAAATCTTGGGTG TTGACACTATTCATAGGTAGAGAG ATTCCTCTAAATTTATAAGATAAAA CTTAGCTCTGTGGGGCCTTGTTTA ATTCATTTTGATGAGTACTTTAATG ATATTAAATTTTTAGAATTTATATT CATATATAGTTAAAGATTTGTTAAA TGTTTGCTGCGACAAACATGTGAT AATGAAATGGGTCAGAAGAATGG AATGGAGGGAGTACTGCTAAGAA TTATCAATCCTATATGATCATATGA TGGATGAAAAAAAAAATTCTTATTT GACTTTTCTGACAATATTGTATATA ATGTCCATATGTGCAGGTTTTATT TTAAAAAATTTCCAGTATTGGAAAT CCAGTTAATTTTATTGGTTATTTAT TTAATTCCTTCTTTITTTCGCATTTG ATATATACAGGTGGAGCATCCAGT AACTGAATGGATTGCTGAAATTAA CCTTCCAGCTGCTCAGGTTGCAG TTGGCATGGGTATTCCTCTTTGGC AAATTCCAGGTAGCTTGCATGTTC CCTTTTTTTATTATATAACTTATGT GCTTCATCTTGTTCTTGTGTATGA GTTGGCTTGCTTTTGCAATTTCAA AATAGAAATTCGGCGATTCTATGG TAAGGAACATGGTGGCGGTTATG ATGCTTGGAGAAGAACATCAGTTG CAGCGACTCCTTTTGATTTTGACA AGGCACAATCTGTGAAACCAAAAG GTCACTGTACTGCCGTACGTGTG ACAAGTGAGGACCCTGATGATGG ATTCAAGCCCACTAGTGGGAAAGT ACAGGTTAATAATGCTATTGTTTTA TAGTTCAAACTATTTTCTCAATTGA TTGCCTTGTCTGTTTTGTGATTCAT GTAAAATTATTTAATTCATTGGTTT CTTTTCTAGGAGTTGAGTTTCAAA AGTAAACCAAATGTGTGGGCCTAT TTCTCTGTTAAGGTATGTCTTTATT TTTTTTAAGCTTTACATCATCCTTT ATGGACTCATTCACGAGCTTAACA ATGGTCAACACTGTCAATTGCAGT CTGGGGGAGGCATTCATGAATTC TCAGATTCTCAATTTGGTAAGTTTA AAGCACATTTTAAAGATGACTAGC AATGAAATGACTATTATAGCTGCC TTTTAAGAATGAAGTTCTTCAACAT CATAGTATTCATTCTCTAATTTAAG ACTGCTGCAAATGGATTGAGAACT GTGCTGTTGTGCATGTGAAATGAG ATATATTGGTTTTTCATAGTGTGTC ATTGTAGACAGTAAATGCTCTTGT TAATTGTTGATGATTGGAATTGGG ATTTAGCATGCTTGGTGTAGTTTT CTCTTGCACAAACAAGTCTCACGG AGTTGATGTGTCATGTTTTTGTCG ATTATTTTTGGTTTAAAACATCAAA TTTTGTTTTCTTTTATTTATAGAAG GCTAATGTTAATTAATTTGTTTGTA GGGCATGTCTTTGCATTTGGTGAA TCAAGAGGGTTGGCCATAGCAAA CATGGTTCATGGCTTAAAAGAAAT TCAAATTCATGGAGAAATTCGCAC GAATGTTGATTATACCATTGATTTT TTAAAAGTAAACCTTATACATTTTA ACTTTGTAGATTTTAATTGAGCAT GTGGCCTTATCCTTTTACATACCC TTTCCGGCTGATTGAGGAATAGGA GTTTCCCGCTATAACCAATGCACA CAATGATTTCAAAATACAAGGATA AGGATTTTGCTGTAAAATGAAGGT TGTGCCTTTCATTTATTTITATITG TTGATGCATTGTGCTGTAAAATTA AGGCCTTCATTTTCATTTATTTTAT TATTTTAAATTGGAGGTATACCAC CTTCTTCTAATTGAATTTTGCAATT GTTGCATGATTTTGCAATTGTTGC ATGATTATGCTCTACTTTTAAAGAT TGAATTTTGCAATTTGTTGTGTGT GGTGTATGTCAATCAATTATATAA AGTAGAATGCTAGAGTGAAAATAA ATGGTCAGCAGCACTATAGCAGA AAAAAAAAACAAATATAAGGTGTC ATATAACACACTCATTAACTCAGG ACTACAACTTTACCCCAACTTGTT ATCGATATTACCCATTTGCTACAT CTCATATGTTCTTACAATTTITITIT ATTCGTCAAATTTGTAAGACAAGA GGCCTTGATTGTGAATTTCCTGTC AATACCCTCTCAATTCTAAAAAAAA TATCATGACTACTAGACTATGAGA GTTTTGTTAGATCTTATCAAGCATA AAGGATTCTATTAAAAAAATAAAAT TATACTAGCAGTTGCTACCATTGG AATGTTAATGTTTATCTTTCTTGGA GGGTTAGTAATAACTTTAATCAAT GAGAGTGACCCACAAAGCTTTCAT GATTCTTTATATAAATGATTATTGT TCCCGCTGTAAAATTGTTCCCGTT GTCTCATTTAATTGTTTAAAATGGA TAAGATTTGATTAGTTTTACTGTTA ATGATGTTTGTGTTTGATTAGTTTT AGTATTTTGCTTAATTGTTGAGATT AATTGTTGAATTAATGTGGGTGAT GAACTGTGCAAGGAAGTGCAGTA GCAGCAGCTATGAGAAATCAGCT ACAGTAGGTCCAAGGAATGTAACA GCAGCTGCAACTGACCTGGGGGC CTGTGCAAGCTGTTCAGGTTGTCT GGACTTGTGCAGGCATCCCCGGGÇ GCTTGTGTAGGCAAGGCAGCAGC AAGTGCAACAGCATCAGGTCTTGT AGGACAGTGTCGACACCGTTTCG GTACATGTAATTTGGCTGTTCAAT TGAATATTATTTGGCATGAAGAAG ATCATGAGTTACATGATTATAGAA AATGATTGTCTTCCAGTGGAGCTA ATCAAGGTCCTCCTAGATAGCCTC AAGAAGGAAAATGATGTATCTCTT GCTTTATTGCTTTCCGAATTTCCC ATCTTTTACTCGGTTGTTGTGTTITT TTGCCCTTATAATCATGCCCGTCT CAGAAAAACTCACCTGCAGCTTTT AATTTGGGTGTCTTTGGCATGCTC ATTCTTTTTTTTTCAACCGATTTCA AATTTTTTGATTTATTTACTGTGTT TTATTGCAACTTGAGTGATTTGTAT TTACTTATGATTGTTATAGAATTTT TGTTATGGTTTGGTTTTTGGCTTAT TTATTAGCTTGGGTCTGAAATTTG ATCTTTCATATGGTCGGGTTTATG AGTTAATTAGGGCGTTTTACTTTC TAGTAATTATTGAGATGATTTATTT TAAAAGAATTAGTTTGACTATATG GAAGAAGTTTTAGTTGTGAATGTA ATATTTGTTTTTTTACAAATACTTT AAATTTGCAATTTTACGGTTGTGTT TAAGAAGAGCAGAAACAGAAGAA GGAAGTGGGAAATCATAGACCAC TTCAAGAGATTGGCTATTTTGATTT TTGAATGAGATTTTATGGTGCTAT TGTTGCTGGTTGATTGTTAGAGGA TCCTTGCATTTGAGCGAAAACAAA GCAATCCAAGTGTAAACTCATGCT AATTTCATGGTTTAAAGTTTTTCAT TGTTGATTTTAGATTTCTTAGTCTT AGATATTTGTTTTTGGTATTCATTT TTTAGGGGAAGGAATGTTTATATT CAATTTTCATCACATCAAGAATTAA CTATGATGGAGCAGAGCACACAT GGGCGAGCAGATGAGGTTGGTTT TTATCATTGATAATTGAATGCAACT AACAGGGGCAAACTAAGTACTCAA CTAACTAATTAGGCAAAGTTACCT ATACGACTATAATTGGACCCAATT AAGGTTACTAGCTTGCTGCAATTT TACCAGTTTGCTAAGCAAAATATT ACATATTGTATATATAGTTAGAATT TGTCCTTTTGTTCGAGGAAAGAAA AAGTAAGGGATGAAAATTTGAGAC TTTCTATTAGCAATTTCATTTAAAT TCCAAAAAAAGGGTCTCATCTATT TTTTTTATAACTTGTTGCTATAAAA TTTGCAATGTGATTGATTGATTGTT AATATGAATTTGTAATATGTTTTAA CAGGATTCCTGTGTCATCTGTGGC TCAAAGGTACTTGACATTAAGATC ACAGTAAGTTCATCCAATTATTATA ATTATCTTATCACTTTTGATATTTT AATTGTTTCTCAAGGATTATTGAG AAAGTTTCAATTCATTTAGGCCCT TTTTAGTTAACAATAGGCTAATTCT ACTGCCTCTTGTTTTAGGTTGCCT CATAGGCACTCTTACTTCTGAAAA TAAACCTCAAATAACCATGATC-
GACCT Kochia gD- 6978 CAGTCTCTGTTTGAAGAGTATTTG scoparia | NA- ACTGTTGAAGAATTGTTCAGTGAC Con- AATATCCAGGTTTGTTATTGCAGT tig TGCAAATTCATCAGTTTTTITGGTC
AACCAATTTGTACCGGGACAAATT GCCACAGTCCTAATTTATTGATGA TCATCGGTCTTCGTGTTTITITTCC CGGTTTGGTTGATTGGTTATCATG TTATGAAGTTGTCACATAAAAAAA ACCTAAATTTACTAATGCACCCAT TTGACCCTAGAGGCTACAGAGTCT TTGGAGTACTCTGTCTCTGTGGAT TATAGTAGCATCCTTTGAAGTATT ACTTTATTTTTTCAAGAAATTGTAG TTCATGTCTTTTGATTCTGATCTTG AAAGGAAGGCTGACATCATTCCAC TTTATTTTCTAATTTCAATCTATAC AGGCTGATGTGATTGAACGTCTCC GCCTTCAACATAAAAAAGACCTGT TAAAGGTTGTTGACATTGTCCTAT CACATCAGGTAGGCAGGAAATTTC AAATAATTCAAATTAAGTTTGAGTT TTCTTTTCCCTTTTCCCTTGTAATA TCTTCCAGGCTTGTTTACTATGTA GTAATAATGGCTTTCAGGGTGTTA AGAACAAAAATAAATTGATTCTCC GGCTCATGGAACAACTGGTTTACC CAAATCCTGCCGCATACCGGGAG AAGCTTATCCGTTTTTCACAACTA AACCATACAATCTACTCTGAGGTT AGTGATTATTCAATTITTITTGTTTAT ATTGTCACACTACAGCATTCACAA AAAGGTTATTAAGTTTATACACTAA TCAATTCCTTCACTATATGCAGTT GGCACTTAAGGCAAGTCAATTGCT TGAACAAACCAAGTTGAGTGAACT TCGTTCTAATATTGCCAGAAACCT TTCCGAGTTAGAAATGTTTACAGA AGATGGTGAAAACATGGACACTC CAAAAAGGAAAAGTGCTATTAATG AGCGTATGGAGGCTCTTGTGAATA CTCCGCTTGCTGTTGAAGATGCC CTTGTTGGCTTGTTCGATCACAGC GATCATACGTTACAAAGGCGGGTT GTTGAGACTTATGTCCGGAGACTT TATCAAGTAATATCTAAGTTCCAA CAGTAAACTTTAACTATCATTTAAT AATGTTATGTCATATAACTCTATTT TTTGTGGGTAATCTCTTTTCTCAG CCTTATCTTGTAAMAAGGAAGTGTC AGGATGCAGTGGCACAGATCTGG CCTCATTGTTTCTTGGGAGTTCAT GGAGGAGCACATTGAAAGAGCAA ATGCCTCTAATGATCTGTCCATCA ACCAGCCCCTTGTTGAGAAACACA GTGAGAGAAAATGGGGAGCCATG GTCATCATAAAATCTCTTCAGTTTT TGCCAACAGTGATTACTGCTGCAT TAAAAGAGACAACACATAATTCAG ATGAAACGATTCCCAGAGGCTCTT TAGAATCAATCAGTCATGGAAATA TGTTGCACATTGCACTTGTGGGTG TTAATAACCAGATGAGCTTGTTGC AGGATAGGTATAGATTCTATTTTTA TGGTTTAAGCAAGATTTTAAAATG TGAACATTGGACTATCCAATTTTAT TTATGTTTATTTATITTATTTATITTT TTGACGAGGACTATCCAGTTTTTT TGAAGAAATATGCTTTGCTTCAAT TATGCAGTCGCTCTTTATAGTAAC CATTCCGGCCTTTTGCTTAACCOTT TTTITCTCTGTGGGGTTTATGAAA TGGAATTTTATACTATGCAGTGGT GATGAAGATCAAGCTCAAGAGAG AATTGATAAGTTGGCAAAAATCCT GAGAGAGAAAGAAGTGAGCTCAG GTCTTCGTGACGTTGGTGTCAGG GTAATTAGTTGCATTATACAGAGA GATGAAGGAAGAACGCCAATGAG GCATTCATTCTATTGGTCAGAAGA GAAACAATACTTCAATGAAGAGCC TTTACTACGTCATTTGGAACCTCC TCTATCAATATATCTTGAATTGGTA TGATATTCTGAGCAAGAAGCTGTT GTTTTTCTTGTTTATTATITTTCITTG TTTCTTAATATGGGTCAAATCATTA TCTTTAACATTTTTGTCACTATTTG ATATAGTTATAAGGTATTTGGCTC ACAACTTTCCTTACACAGGACAAG CTCAAGGTCTATGAAAATCCCAAA TATACTCCTTCTCGGGATCGTCAA TGGCACCTGTATACTGTCATGGAC AAGCCATCTATTCGACGAATGTTT TTGAGGACACTTGTCAGACAGCC CACTTCCGAGTTCAGTGGGGTTG AACTAAAAATTCTTCAAACACAAA GGCCCATCTCCTTTACTTCAAGAA GCATTCTGAGGTCTTTAACAACTG CAATGGAAGAATTAGAACTCAATG CGCACAATGCTACCTTGAAACCTG ATCATGCTAATATGTACCTGTACA TTGTAAGAGAGCAACAAATACATG ATCTTGTCCCATATCACAGGTTCT AATTACTATTCTTAATTTTATGTGT CTCATTTGTGGTTATTGATGCAAC TTATGCTTTAAGAGGGATTATTTT GATCCGTTAATCCAGGGAGGTGA ACATTGATGACGAACAAGAAGAGA CAGCTGTTCATATGTACTTGGAAG AGCTTGCGCTTGAAATCCACAGTT GTGCTGGTGTGAGAATGCATAAA CTAAATGTATGTGAGTGGGAAGTA AAACTTTGGATATCATCTTCTGGT CAAGCCAATGGTTCATGGAGAATC ATTGTTACTAATGTGACTGGTCAT ACATGCACTGTACATGTAAGTTTG AACTATGATGATTTTTTCCTATAAT TTTCTGTAAAGGTTTTTAGTATTGG CCGTGTTTAGTAATTTCTTTCAACA CTCAGATATTTATGCCAGTTTTTGT AAGAATTACAGAAATAGTAGCATG TTTTTAGTGCCCAAGTTCTTTCTTT GTCCTTTTGCCCAGCAATATCOTITT AATAATTTATGGTTATAAACTATAA GATATTATGAGACTATACATCGAG AAAAATCTAAATACATCTTCCATTA CAACCTTTGATTITTITITIITITIITT TTTTAAATTGAAAAAACAATGGGT AAAGGTGATACATGAATCTTGTAA AACACAAACAATGACCATACATAT GGGACGGAGGGAGTAATAATGGT TTGTATATTGGCACTTATAAAGAA AAAGGTTATGCACGATTAATTTAT GTCTTGTAGACGTGTATCACATAA TGTCTTCTTTAGTTTGCTGACCTTT TTCTACTAATGTTATGCAGGTTTA CCGTGAGTTGGAGGATAACAACC TTCATGAAATGATCTACCATTCAG TATCTGTTCAAGGTCCTCTTCATG GAATACCAGTGAATGCACCCTATC AACCACTTGGAGTCATTGCTCGTA AAAGACTGCAGGCCATGAAAAAC AGCACAACCTATTGTTATGATTTC CCACTGGTAAGAGATATCAAACTC CACTGTACCACAATACTACAAAAG CAGAATTTACAGTATTAGGTTTCC TTTCCTCCAAAAAAATCAAGGGTT GATGCATGACTTACATTCGAGTGT AACTATGGTTCTTGTTTACGCTCA ACTAGTAATGAAATAGGAATATAA ATCTAATAAAGATTTACAAATTTTG GAGAGAGGCGGGGTTGTGTAACT GTGGGACTTTGTAAAGGTTTAAAG TTAGTTAGGTGGAGATGCAGGGT TTATATTTAGTTTATGAGGAAACTA CAAGTTTACAAGATTTTAATAGGT AATACGTGTAAAATTTTAAAAGATA TCGGAAAAGTTGCTAGAATAAAGG AAGTTTAGCTAACTTTAAAGAATAT TTGTCTTAGTATTTTGGATTATTGT AACTTTGTAAATAAAAATAGTTTCA CATTTTGTTAAGATTTCAAGTTTGG CTTTCGCACACAATGGGTCTGTTC TTTTCACCTTATCTGTACTTATCCG AACTTTTCCGAACTTCTATGAACTT GTTTTGTGAGAGAGAAAAATAATA AGTTTGTTCTTTTCAACTTATTITTT TATTATCTGAACTTATTTGAATTTA TTTTTTCTGAAATTAAGTAAAAATA AGCTCAATAGAACATACCCAATGT AGAAAAATAGAATTAAACAAAGAA ATAGTGGGGAAAAAAAGTGGAGG TGATTTGTGTCTCTTGTGGGCATT AGTTTAGTAACAACTAGAGTAATG GATATAGATGACTTATTTITAATTC ATTGTATGACATACATCAAAAACC TGAAATTTTAGTGATATCAAATTG GCCTTAATTAGTAATTTAGTTGTTT GATATTGTTGGTTATACAAGTGAA AACAGATACTTAATATGCGAATGA TTGTGCCTATAGTGATTATGTGAC TGTGTTGTTAAATATAAAAGTGTTT CAGTGTTTTTAAGACAAGGGAAGT AGGGAACCATAAACAAAAATACGA AGCATATCTTGGGTGTTACCTAGT TTTGTCCTATTTCTCAATTATTGAT TTAGTTGTTTAATTTGTTGGTTATA AAAGAGAAAAACCGGGATTGTTG GTGTGCAAAGATTGTACCTATAGT GATTATGTGACAACGTTGTCAAAT GTAAAAGCATTGCAATTTTTGTGA GGCAAAGGAACCATAAATAAAAAT GCGAAACATGGCTTGGGTGTTAC CTAGCTTTGTCCTATTTATTGAACT ATGTGATTGTACCTCAAATTTTTAT ATTTGATGTTGTATCGATCAACTT GCTTTAGCTCACGTTAGCATTTAT CTGTTTTTCTATTGGAAAATTGAC CTGAAATTATTGGGAATGTTITTCT CAGGCTTTCTCTACTGCCTTAGAG CAATCATGGGCATCTCAAGCTCC GCTTCTGAAGAAACCCGTTAACAA AAAAGTTTTGAAAGTCTCAGAGCT AGTATTTGCTGATTCAAATGGCAC CTGGGGAACACCAGTTGTCCCGA CAAATCGTGAACCTGGTCTTAACA ATATTGGCATGGTTGCCTGGTCCA TGGAGATGTCAACTCCTGAATTCC CTGATGGAAGAACCATATTGGTTG TAGCAAATGATATCACCTTCATGG CTGGATCATTTGGGCCAAAAGAA GATGCTCTCTTCCAGGCAGTTACA GATCTTGCTTGTTCCAAAAAAATT CCTCTGATTTACCTGGCTGCTAAT TCTGGTGCTCGACTGGGTGTTEC TGAAGAGGTAAGAGCATGCTTTAA AATTGGTTGGACCGATGAGTTGAA CCCTGAGCGGGGGTTCCAGTATA TCTACTTGACTCCTGAAGATTATG AGCGTATAGGGTCAGCAGTTATA GCCCATGAGTTAGAACTCCAAAAT GGAGAGACTCGGTGGGTTATAGA CACTGTTGTAGGGAAGGAGGATG GGATAGGTGTTGAGAACTTATCTG GAAGTGGAGCTATAGCTGGTGCC TACTCAAGGGCATACAAAGAAACT TTTACTCTAACTTTTGTAACAGGAA GAACAGTAGGTATTGGTGCCTATC TTGCTCGCCTTGGGATGCGTTGTA TCCAAAGGCTTGATCAGCCCATTA TTCTGACAGGCTTTTCTACGTTAA ATAAACTTCTTGGTCGTGAGGTTT ACAGCTCACAAATGCAACTTGGC GGGCCCAAGATTATGGGTACAAA TGGTGTTGTTCATTTAACAGTTTC AGATGACCTTGAAGGCATTTCAGC TATTGTCAAGTGGCTCAGCTATGT TCCATCCTACTCAGGAGGTGAACT TCCTATTTCACGTTCTTTAGATCCT CCTGAAAGACAGGTTGATTATTTG CCTGAAAATTCTTGTGATCCCCGT TCTGCTATATCTGGTACACTTGAC TCTAATGGCAATTGGCTTGGTGGA ATTTTTGACAAAGATAGTTTTGTITG AAACCCTAGAAGGCTGGGCAAGG ACAGTTATCACTGGCCGGGCCAA ACTTGGTGGAATCCCAGTTGGGA TAGTTGCTGTTGAGACACAAACTG TGATGCAAGTTATCCCAGCAGATC CTGGTCAGCTTGATTCGCATGAG CGAGTGGTCCCACAAGCTGGACA AGTATGGTTTCCAGATTCTGCAAC TAAGACAGCACAAGCTTTGATGGA TTTTAACAGGGAAGAACTTCCACT TTTCATTCTAGCTAACTGGAGAGG CTTCTCTGGAGGGCAAAGGGATC TCTTTGAAGGGATTCTTCAGGCAG GGTCCACAATTGTCGAGAACCTTA GGACTTATAATCAACCTGTTTITTTG TTTATATCCCCATGATGGGTGAAC TTCGTGGTGGGGCATGGGTTETC GTAGACAGTAAAATCAATTCGGAC CATATTGAGATGTATGCTGATCAG ACAGCTAAAGGAAATGTTCTTGAG CCAGAAGGAACGATTGAGATCAA GTTTAGAAACAAGGAATTAATTGA ATGTATGGAAAGGCTTGATCAACA TCTCATCAATCTTAACGCAAAACT CGTCGAAGCCAAAAACTCCAATTT ATATGTTAATATCGAACTCCTGAA ACAGCAGATAGAAGCTCGGCAGA AGCAACTTTTGCCTCTATATACTC AAATAGCCACAAAATTTGCTGAAT TGCATGATAGTCCTTATAGAATGG CTGCGAAAGGAGTCGTCAAGGAA GTCCTGGATTGGAGCAATTCTCG CTTATTCTTCCACAAAAGACTGTA CAGGAGAGTTATGGAGGAATCAC TTGTCAAGACCGTCCGAGATGCT GCTGGTGAAGCAATGACCCACAA GTCTGCCATGGAATTGATCAAGCA ATGGTTTGCTGAGTCTGATAGTAC TAGTGGAGTGGGAGCTGATCCTT GGTCTGATGATGAAGCTTTCTTCA AGTGGAAAGAAAATCCTGCTAATT ATGAAGAAAAGCTAATCGAGTTGC GCATACAGAAGGTATTGCATCAGC TGTCAAATATTGGCAACTCGGCTT CTGATCTGAGAGCTCTTCCTCGG GGTCTTGCTGCCCTTCTCCAGA-
AGGTATCTCTAAGTC 81 Kochia gD- 4017 TTCTTTTCAACTTATTTTTTATTATCO scoparia | NA- TGAACTTATTTGAATTTATTITITTTC Con- TGAAATTAAGTAAAAATAAGCTCA tig ATAGAACATACCCAATGTAGAAAA
ATAGAATTAAACAAAGAAATAGTG GGGAAAAAAAGTGGAGGTGATTT GTGTCTCTTGTGGGCATTAGTTTA GTAACAGCTAGAGTAATGGATATA GATGACTTATTTTTAATTCATTGTA TGACATACATCAAAAACCTGAAAT TTTAGTGATATCAAATTGGCCTTA ATTAGTAATTTAGTTGTTTGATATT GTTGGTTATACAAGTGAAAACAGA TACTTAATATGCGAATGATTGTGC CTATAGTGATTATGTGACTGTGTT GTTAAATATAAAAGTGTTTCAGTG TTTTTAAGACAAGGGAAGTAGGGA ACCATAAACAAAAATACGAAGCAT ATCTTGGGTGTTACCTAGTTTTGT CCTATTTCTCAATTATTGATTTAGT TGTTTAATTTGTTGGTTATAAAAGA GAGAAACCGGGATTGTTGGTGTG CAAAGATTGTACCTATAGTGATTA TGTGACAACGTTGTCAAATGTAAA AGCATTGCAATTTTTGTGAGGCAA AGGAACCATAAATAAAAATGCGAA GCATGGCTTGGGTGTTACCTAGC TTTGTCCTATTTATTGAACTATGTG ATTGTACCTCAAATTTITTATATTTG ATGTTGTATCGATCAACTTGCTTT AGCTCACGTTAGCATTTATCTGTT TTTCTATTGGAAAATTGACCTGAA ATTATTGGGAATGTTTTTCTCAGG CTTTCTCTACTGCCTTAGAGCAAT CATGGGCATCTCAAGCTCCGCTT CTGAAGAAACCCGCTAACAAAAAA GTTTTGAAAGTCTCAGAGCTAGTA TTTGCTGATTCAAATGGCACCTGG GGAACACCAGTTGTCCCGACAAA TCGTGAACCTGGTCTTAACAATAT TGGCATGGTTGCCTGGTCCATGG AGATGTCAACTCCTGAATTCCCTG ATGGAAGAACCATATTGGTTGTAG CAAATGATATCACCTTCATGGCTG GATCATTTGGGCCAAAAGAAGATG CTCTCTTCCAGGCAGTTACAGATC TTGCTTGTTCCAAAAAAATTCCTCT GATTTACCTGGCTGCTAATTCTGG TGCTCGACTGGGTGTTGCTGAAG AGGTAAGAGCATGCTTTAAAATTG GTTGGACCGATGAGTTGAACCCT GAGCGGGGGTTCCAGTATATCTA CTTGACTCCTGAAGATTATGAGCG TATAGGGTCAGCAGTTATAGCCCA TGAGTTAGAACTCCAAAATGGAGA GACTCGGTGGGTTATAGACACTG TTGTAGGGAAGGAGGATGGGATA GGTGTTGAGAACTTATCTGGAAGT GGAGCTATAGCTGGTGCCTACTC AAGGGCATACAAAGAAACTTTTAC TCTAACTTTTGTAACAGGAAGAAC AGTAGGTATTGGTGCCTATCTTGC TCGCCTTGGGATGCGTTGTATCCA AAGGCTTGATCAGCCCATTATTCT GACAGGCTTTTCTACGTTAAATAA ACTTCTTGGTCGTGAGGTTTACAG CTCACAAATGCAACTTGGCGGGC CCAAGATTATGGGTACAAATGGTG TTGTTCATTTAACAGTTTCAGATGA CCTTGAAGGCATTTCAGCTATTGT CAAGTGGCTCAGCTATGTTCCATC CTACTCAGGAGGTGAACTTCCTAT TTCACGTTCTTTAGATCCTCCTGA AAGACAGGTTGATTATTTGCCTGA AAATTCTTGTGATCCCCGTTCTGC TATATCTGGTACACTTGACTCTAA TGGCAATTGGCTTGGTGGAATTTT TGACAAAGATAGTTTTGTTGAAAC CCTAGAAGGCTGGGCAAGGACAG TTATCACTGGCCGGGCCAAACTT GGTGGAATCCCAGTTGGGATAGT TGCTGTTGAGACACAAACTGTGAT GCAAGTTATCCCAGCAGATCCTG GTCAGCTTGATTCGCATGAGCGA GTGGTCCCACAAGCTGGACAAGT ATGGTTTCCAGATTCTGCAACTAA GACAGCACAAGCTTTGATGGATTT TAACAGGGAAGAACTTCCACTTTT CATTCTAGCTAACTGGAGAGGCTT CTCTGGAGGGCAAAGGGATCTCT TTGAAGGGATTCTTCAGGCAGGG TCCACAATTGTCGAGAACCTTAGG ACTTATAATCAACCTGTTTITGTTT ATATCCCCATGATGGGTGAACTTC GTGGTGGGGCATGGGTTGTCGTA GACAGTAAAATCAATTCGGACCAT ATTGAGATGTATGCTGATCAGACA GCTAAAGGAAATGTTCTTGAGCCA GAAGGAACGATTGAGATCAAGTTT AGAAACAAGGAATTAATTGAATGT ATGGAAAGGCTTGATCAACATCTC ATCAATCTTAACGCAAAACTCGTC GAAGCCAAAAACTCCAATTTATAT GTTAATATCGAACTCCTGAAACAG CAGATAGAAGCTCGGCAGAAGCA ACTTTTGCCTCTATATACTCAAATA GCCACAAAATTTGCTGAATTGCAT GATAGTCCTTATAGAATGGCTGCG AAAGGAGTCGTCAAGGAAGTCCT GGATTGGAGCAATTCTCGCTTATT CTTCCACAAAAGACTGTACAGGAG AGTTATGGAGGAATCACTTGTCAA GACCGTCCGAGATGCTGCTGGTGE AAGCAATGACCCACAAGTCTGCC ATGGAATTGATCAAGCAATGGCTT GCTGAGTCTGCCATGGATAGTACT ACTAGAGCGGGAGCTGATGCTTG GGCTGACGATGAAGCTTTCTTCAG GTGGAAAGAAAATCCTGCTAATTA TGAAGAAAAGCTAATTGAGTTACG CATACAGAAAGTATTGCATCAGCT TTCAAATATTGACAACTCAGCTTC TGATCTGAGAGCTCTTCAGCTTCG TCAGGGTCTTGTTGCCCTACTTCA GAAGGTATCTCTAAGGTTCCTCCA CACACACACACACCCCACCCACC AAAAAAAACACACACACACACATT CACAAGAAAAGTAGAATTGCTAGT GAAATAACTTCATCGTGTTCAATG CAGGTGAATTCCTCAAGCCGAGC AAATCTAGTAGAGAAACTCGAGAA AGTGCTCAATTGATTTGGTAATGA TCCTGCAGAAAAACCTCTTGGTAT ATGGTGGTATGCAAATGCCATATC TGAAAGATTGATTAGGCAAGTTGA GACAGAGACAGGCACAGTTGTAA TAATGGGATCTATCAAACCAGAAG ACGTTATAACTAAGCTCAAAGATG ATGGTGATTTTGACCGTCTTCGTC TCAAAATCATTCGTAAGCTCAAAC AAAACGTATTTCTTTCTCCTTTTCA TCTTCTACTGTATATTAAATGGTTT AAAATTTGATCTTGATTAATGGGT AATCTTTATAATTTTATCTITTTITAT TATAATACAAGAATGATATGCATAT TTTTATTTTGTTATTAATTACCAAA TGCACTTCAGTTTACATTGCCGGT TTTGAAGTTTTGGAAGCAGAATTG GGGTTAGAATGCTAGATATTATTG CTTGTTGATCATTTATTCAGTTACT TACATTGTTTGGTTGAAATCGGAA TTAAAAGAGCACAAATTGTATGGT TTCTAACTCGACTTCACAATAAGA GTATAGATGCTCACTGTTGTGTTG TGTGTTTTGTTTTTGTTAAGAAATA TTGGTTTTGATTGATGATGCTCCA AGCCTCGAGTGAGCGTGTTGATG AAATAGAGTACTGAATTAAAGGTT ATCATTTTATCGAATGTCAGATTAA TTGTTAATTGTTGCTCGGAGTCGG AGTTTAAATGAGAATCATTITTATCG AATGTCTTAAGTTATCAGGGCAGA TATTTITTITTCTAGTGGGTATGGA CTCTTGAGCCTCTTTITTCTGTATE AAACTGTCCTGTTGGTTGTTCAAA TTATGCAAATCATGAAGAGATTAC TTTGGTCTCAGGTTTGCTTCGC-
CATCCTTCCCAATGAATC 82 Kochia gD- 2591 ACAATGAGGCCTGGTATTTTATAA scoparia | NA- AAAAGAAAAGAATTGTTAGTGCTA Con- AAAACTCCTCGTATACAAAGTTAC tig AAACAACACCCAGCATCCATTTTG
CATATCTAACACAAAATATACAAAA CATATTAGGCAGGACAACCAAGAA TTCAGAGGGAAATCTTAAAATATG TTAATGCGGGCAGTACGATTCCAC TGCGAAAAATTTACTCACTTAGAC CAAGGTTAGGAACAACAATGTACA CGAATGTTGAGCAGAGAAAATATA TACAAATGAAGCAGTTCATATACA ATAAAAGGCAGAGAAGATGCCCA ATATTCCCCTTTCAATCGAAATTCA CAATTGATCTTGTCATTAGAAAAG TGAAACAAGAGGGTCTCATCGTAA TTAAGGGAATGAAGTATGCTTCAG CCATACCCAACAGTACCTTACAAT AACTGTCAAGTTTCCTCACTATCOT TGAGCTGCCCAAGATGGTGCAGC AAGCACTTGCGCTGCTAGTCTCA GAAAAACAACTATAGGCAATCCCA TCAAGATCTTGTTTTCTTCCAGGA ATTAAAATAGTTCAGTTTCATCAAC ATCCAAACATCAAAAACAAAATGA CCTGAGATAGAAAAGAGCACTTAC AAGCACCTTTTGATGTGCAACAAA AGAACAATTTCCTCAGACGAAGCA CTCTTTCTCTTACCCAAAATAGGC TACACACTCATTCAGATCTCAGGG TTGCTACACTCATATCGATCCCAG AAATCTTTCGTTTTTAGGGAGCAG ATTTCCTCGCAAATGAGCATGTAA GTACTAGTTTGAAATTATCTACACT ACAACTTGACATCAATATCAGACT CTGACAGCCAGGGCCAAAGCCAT CGGATTTGGTTACTCATCTGCTCA CACAAATTGAAATGTCCGGGACAT AGAAGAAAAAAATACACCTATGAT GGTCTTGCGAAAAACTATTAAATA AAGTACTATATTTATCTTCTTATTA GACCATTTTAGATCAGAGAATGTT GCTTAAAATATCCTAAGGAAAAAG CTCAGGCTATATGATTGTATTACA CCATATTATTGATATCCCAGAGTG CACTAAGGGACTGGTGAATTTGGT GTTAAGCAGATGTTATCAATCCCA ACTACATCATATCCCATCTACTAG GCAGGCAGCGGCAAGGCAATAAT GTTAGGGAAAAAAATCCCATTATC TCCATTAGAAAACTATCATATTAGT CTTTAAAATTTAAACAAAAAGGAAT TTCAAAACAAAATGTTGATTTCAAT AGGCTATGTAACCTAAGCAATGTT AACAAGCAGAATGCTGGTTTCACT AGAAGAGCTAGTGGGCTACAGGC TACAAATTATCTAAGCCATTCTTGT TTCCTATGATTAGTTTTAATAGGCA TAATAGCATAAATTCTTCTATACAC ATCTGCCGGCATTTACTGCATCAC TACATTACCCGTTGTTGATGAATT TTTTTTATGCTCTTGGAGGGAAAA GGTCAATTCATAGTATTTGGATTG CAAACAATGGAATGACAACTGTTA AATTTATCAGAAGTGTTCGGACAT GGGCTTATGAAAATTTTGGAACAG AGAAGGCTATTGTATTAGTAGCAA TGGCTACTCCAGAAGACATGAGA ATCAATGTTGAACACATTCGAATT GCTCACCAGTTTGTTGAGGTTCCT GGTGGGACTAACAACAACTATGC CAATGTACAACTCATTGTTGAGGT AAATCCTGCTTTAGTAACACTGAT CTTCCGTGTTTTTGCACTAATGTT GATTATACCATTTATCTTTTAAACG TAAGCCTTATACATGAATTTTCCC CCTACACTGTTCACTGTTTTTTCAA TTAGAACCTAAATTTGTCTTTGTTT TTCCCTTTCTCTAGTCTTTGGATTA CAAAGATAATAAAATTCATACGGG TTGGTTAGATAGTAGAATTGCAAT GAGAGTCAGAGCGGAAAGGCCCC CCTGGTTCATCTCTGATGGGGGGA GGTGCACTCTACGTGTGTACAACT TTTCTCTTAAATTTTITTTCCTTCCA AAAGCTTGATGTGTCACTTTCGTT TATTTTTATAATGAATAATTTTAAAT ACTTCGTAATTTCTTTCTCCOTTTCOT CCCTATCTTCAGTAAGCOTTCTTCOT AGTAGTGCAGCTACTGTTTCAGAA TATATTGGCTATCTTGAGAAAGGT CAAATTCCTCCAAAGGTAATCCAA ACACCAGATGCTGTTGAGATATAA TTGTTTTTTAAACACTAATTGTTTC TTTCAGTAAATTACATCAATATTTG TGTGGATTGCAGCATATTTCACTT GTCCACTTGGAAGTTACTTTGAAT ATTGAGGGGAGCAAGTACACTATA AGTTTATTATTAAGTTATGTGAATT TCATTTTTCGTTCATGGTTTCTCCT GTTTACTTGATGTTAATCATCATAA CATGGTTGATTCTGTTCTCCAGAT CAAAATGGTGAGAGGCGGTCCAG GAAGCTACAGATTGTGATTGAATG AGTCAAAGATTGAGGCAGAAATAC ATACATTAAGTCATTAAGAGATGG GGGTCTTTTAATGCAAGTAAGA-
ACTTAATTTITTA 83 Kochia gD- |704 GTGTTCGGACATGGGCTTATGAAA scoparia |NA- ATTTTGGAACAGAGAAGGCTATTG Con- TATTAGTAGCAATGGCTACTCCAG tig AAGACATGAGAATCAACGCTGAAC
ACATTCGAATTGCTGACGAGTTTG TTGAGGTTCCTGGTGGGACTAAC AACAACTATGCCAATGTACAACTC ATTGTTGAGGTAAATCCTGCTTTA GTAAAACTGATCTTCCGTGTTTTT GCACTAATGTTGATTATACCATTG ATCTTTTAAACGTGAGCCTTATAC ATGAATTTTCCCCCTACATTGTTC ACTGTTTTTTCAATTAGAAGCTAAA TTTGTCTTTGTTTTTCCTTTCTCCA GTCTTTGGATTACAGAGATAATAA AATTCATACGGGTTGGTTAGATAG TAGAATTGCAATGAGAGTCAGAGC GGAAAGGCCCCCCTGGTTCATCT CTSGTGGGGGGAGGTGCACTCTAC GTGTGTACAACTTTTCTCTTAAATT TTTTTCCTTCCAAAAGCTTGATGT GTCACTTTCGTTTATTTTTATAATG AATAATTTTAAATGATTTCTITTTCTC CTTTCTCCCTATCTTCAGAAAGCET TCTTCTAGTAGTGCAGCTACTGTT TCAGAATATATTGGCTATCTTGAG AAAGGTCAAATTCCTCCAAAGGTA ATCCAAACACCAGATGCTGTTGAG ATATAATTGTTTTTTAAACACTA-
ATTGTTT 84 Lolium cD- |842 GACATGAGGATAAATGCAGAGCA multiflo- | NA- CATTAGAATTGCTGATCAGTTTGT rum Con- TGAAGTACCTGGTGGAACAAACAA tig TAACAACTATGCAAATGTCCAACT
CATAGTGGAGATAGCAGAGAGAA CAGGTGTTTCGGCCGTTTGGCCT GGTTGGGGCCATGCATCTGAGAA TCCTGAACTTCCAGATGCACTCAC TGCAAAAGGAATTGTTTTTCITTGG GCCACCAGCATCATCAATGAACG CATTAGGTGACAAGGTTGGTTCAG CTCTCATTGCTCAAGCAGCAGGG GTTCCGACTCTTGCTTGGAGTGG ATCACATGTGGAAATTCCATTAGA ACTTTGCTTGGACTCTATACCTGA GGAGATGTATAGGAAAGCTTGTGT TACTACCGCGGATGAAGCAGTTG CAAGTTGTCAGATGATTGGTTATC CTGCCATGATCAAGGCATCCTGG GGTGGTGGTGGTAAAGGGATTAG AAAGGTTAATAATGATGATGAGGT TAAAGCACTGTTTAAGCAAGTACA GGGTGAAGTTCCTGGCTCCCCAA TATTTATCATGAGACTTGCATCTC AGAGTCGACATCTTGAAGTCCAG CTGCTTTGTGATCAATATGGCAAT GTAGCAGCACTTCACAGTCGTGAT TGCAGTGTGCAACGACGACACCA AAAGATAATTGAGGAAGGACCAGT TACTGTTGCTCCCCGTGAGACAGT GAAGGAGCTTAGAGCAAGCGCAA GGAGGCTTGCTAAGGCTGTGGGA TATGTTGGTGCTGCTACTGTTGAA TATCTCTACAGCATGGAGACTGGT GAATACTATTTTCTGGAGCTTA-
ATCCACGGTTGCAGGTTGA 85 Lolium cD- 732 GCAGAGCTACGTGGAGGGGCTTG multiflo- | NA- GGTCGTGATTGATAGCAAGATAAA rum Con- TCCAGATCGCATTGAGTGCTATGC tig TGAGACAACTGCAAAAGGGAATG
TTCTCGAGCCTCAAGGGTTGATTG AGATCAAGTTCAGGTCAGAGGAA CTCCAAGAATGCATGGGTAGGCT TGATCCAGAATTGATAAATCTGAA AGCACAACTCCAGGGAGCAAAGC ATGAAAATGGAAGTCTATCTGATG GAGAATCCATTCAGAAGAGCATC GAAGCTCGAAAGAACAGTTGCTG CCTTTGTACACTCAAATCGCGATA CGGTTTGCTGAATTGCATGATACT TCCCTCAGAATGCTTGCTAAAGGT GTGATTAGGAAAATTGTAGATTGG GAAGAATCTCGGTCTTTCTTCTAC AAGAGATTACGGCGGAGGATATC TGAGGATGTTCTTGCAAAAGAAAT AAGAAGTGTAATTGGTGTCGAGTC TTCTCACAAATCAGCAATGGAGTT GATTAAGAAGTGGTACTTGGCTTC TGAGACAGCTGGAGGAAGCACTG AATGGGATGATGATGATGCTTTTG TTGCCTGGAGGGAGAACCCTGAA AACTACAAGGAGCATATCAAAGAG CTTAGGGCTCAAAGGGTATCTCA GGTGCTCTCAGATGTTGCAGACT CCAGTTCGGATTTACAAGCCTTGC CACAGGGTCTTTCCATGCTACTAG ATAAGATGGATCCCTCTAGGA-
GAG Lolium cD- |/668 CGTTATTGATCTAAAACGATGCTC multiflo- | NA- TGCCAGGGCCAACAGAACTACAT rum Con- ACTGCTACGATTTTCCCTTGGCAT tig TTGAAACTGCAGTGACGAAGTCAT
GGTCTAACATTCCTAGAAACAACC AATGTTATGTTAAAGCGACAGAGC TGGTGTTTGCTGACAAGAATGGGT CGTGGGGCACTCCTATAATTCCTA TGCAGCGTGCTGCTGGGCTCAAT GACATCGGTATGGTAGCCTGGAT CTTGGACATGTCCACTCCCGAATT TCCCAGTGGCAGACAGATTATTGT TGTCGCAAATGATATTACTTITTAG AGCTGGATCATTTGGCCCAAGGG AAGATGCATTTTTTGAAGCTGTTA CCAACCTGGCTTGTGAGAGAAAG CTTCCTCTTATCTATTTGGCTGCA AACTCTGGTGCTCGGATTGGCATT GCCGATGAAGTTAAATCTATCTTC CGTGTTAAATGGATTGATGATAGC AACCCTGAACGTGGATTTGATTAC GTTTATCTGTCTGAAGAAGACTAT GGCCGTATTAGCTCTTCTGTTATA GCGCACAAGACACAGCTAGATAG TGGCGAAATAAGGTGGGTTATCG ATTCTGTTGTGGGCAAGGAGGAT GGGCTAGGTGTGGAGAACATACA TGGAAGTGCTGCTATTGC-
CAGTGCGTATT 87 Lolium cD- |469 AGGGCGTCCTCCAATGCGCCATT multiflo- | NA- CCTTCCAATGGTCATTTGACAAGC rum Con- TATATTATGAGGAGGAGCCGATG tig CTCCEGCCATGTGGAACCTCCTCT
GTCCACATTCCTTGAATTGGACAA AGTGAAATTAGAAGGTTACAGTGA CATGAAATACAATCCATCGCGTGA TCGCCAGTGGCACATTTACACACT GAACAGTGAAGATCCAAAATCAAA TGACCAAAGGATATTCCTTCGTAC AGTTGTTAGACAGCCAAGTTTAAC CAATGGGTTTTTGTTTGGAAGTAT CGACAATGAAGTAGGCCGTTCTC AGGCCACATCGTCATTCACATCTA ACAGCATACTTAGATCATTGATTG CAGCGCTAGAAGAAATAGAGTTAC ATGCTCATAATAAGGCCATGAGGT CACGCCATTCCCACATGTATCTGT GCATGTTGAGAGAACA- ACGGTTGTCTGATCTAATTC-
CATTT 88 Lolium gD- 4094 CACTTCTAAAGCCACAAGTAGAGG multiflo- | NA- ATCCCATTCEGCAGGCGATGGGGET rum Con- GTAATGGTTGTAATCAAGTCTCTT tig CAGCTTCTGCCAACTGCAATTGAA
GCTGCATTAAAGGAGACTTCACAT TATGGAGCAGGTGATGCAAATGT CTCCAATGGTAGTCCTATAAGATC TAATAATAGCAATATGCTGCATATT GCTTTGGTTGGTATCAGAAATCAG ATGAGTACTCTTCAAGACAGGTTC GTTTACACTCTCTACTCTTTGCGA TTCTTTATTCTTGATGAAACACAAA ATATCATAAGAGTGATTCTATGAA CTGGTTCTGAATTTCATGAAATTTT TAGTTACACCCTCCACTTTGTTTT CTCTTTTTAGTGGTGATGAGGATC AAGCACAAGAAAGGATCAACAAAC TTTCCAAGATTTTGAGGGATACCA CTATAACATCACATCTCAATGGTG CTGGTGTTAGGACTGTCAGCTGC ATTATCCAAAGAGATGAAGGGCGT CCTCCAATGCGCCATTCCTTCCAA TGGTCATTTGACAAGCTATATTAT GAGGAGGAGCCGATGCTCCGCCA TGTGGAACCTCCTCTGTCCACATT CCTTGAATTGGTATGCAGCTTTAG TTTTGGCTTATGTTCTCTTCAACAA TACCAGTACCTCTAATAACTTATCT GTAAATACAGGACAAAGTGAAATT AGAAGGTTACAGTGACATGAAATA CAATCCATCGCGTGATCGCCAGT GGCACATTTACACACTGAACAGTG AAGATCCAAAATCAAATGACCAAA GGATATTCCTTCGTACAGTTGTTA GACAGCCAAGTTTAACCAATGGGT TTTTGTTTGGAAGTATCGACAATG AAGTAGGCCGTTCTCAGGCCACA TCGTCATTCACATCTAACAGCATA CTTAGATCATTGATTGCAGCGCTA GAAGAAATAGAGTTACATGCTCAT AATAAGGCCATGAGTTCATGCCAT TCCCACATGTATCTGTGCATGTTG AGAGAACAACGGTTGTCTGATCTA ATTCCATTTTCAAGGTCAGTCAAA ATATACTTATGTTCTCAATAAAATA CACTGCATTAAATGTGCTCATATG ATGCTCACTTGGTTTGTGCTTCTC ATGGTGTTAGGATGATGGGTGAA GTTGGTCAAGATGAGGAGGCAGC ATGCACACTTTTGAAGCATATGGT TATGAATATATATGAACATGTTGG TGTCAGGATGCATCGCCTTTCTGT GTGCCAATGGGAAGTGAAGCTAT GGTTAGATTGTGATGGGCAAGCC AATGGTGCTTGGAGAGTTGTCATT ACCAATATAACTGGGCATACCTGC ACTGTTGATGTAAGTTACCTTAGC GATTGCTGTATTGCACTACTATGT GAACAACAGCATCTACAGTTCTGC ATATCATAAAGAATGCTACCTCTG ATGGCCCCATAGATCATCATATAT GATTATATTTTAGTTAGTAAATAGA ACATGGTCATCATTTCCATCATTC GTGTCATGGACATTCTCTCAACTG ATGCCTTTAAAGGGTCTATTAAAG ACCACTTAAAAATAATTAAGTACTA TTTTCTCTTTATTCCAATACTCOTTA TATGCTCACATTCGTTTGACTTTC AGATTTACCGAGAAGTAGAAGACT CCAATACGCATCAGATTTTCTACC GCTCTGCCACACACACAGCTGGT CCTTTGCATGGCATTGCATTGCAT GAGCCATACAAACGTTTGGCTCCT ATTGACATGAAACGGTCTGCGGC TAGGAAAAACGAAACTACATACTG CTATGATTTCCCATTGGTGAGTTG GTTGCGTTTGTTAATTTACTTITTTA TCTAACATTAGTTCGCATGATTAA CCTGATCAACTGAGTTTGCTAATA ATACTCTGTCCACAGGCATTTGAA ACAGCATTGAAGAAATTGTGGAAA TCTAGTGCTTCACATCTTGCAGAA ACTAACCAGCATAATCAGCAGTAT GCTGAAGTGACAGAGCTTTTATTT GCTGATTCAACTGGATCATGGGG TACTCCTTTGGTTCCAGTTGAACG TTCTCCATGTGTCAATGATATCGG CATTGTTGCTTGGAAGATGAAGCT CTCCACGCCAGAATTTCCAGGCG GCCGGGAGATTATAGTTGTTGCAA ATGACGTGACGTTTAAAGCTGGGT CTTTTGGTCCTAGAGAAGATATAT TCTTTCATGCTGCTACCAATCTTG CCTGTGAGAGGAAAATTCCTCTAA TCTACTTGTCAGCAACTGCTGGTG CTAGGCTTGGTGTGGCAGAGGAA ATAAAGTCGTGCTTCCATGTTGGA TGGTCTGATGACCAGAGTCCTGA ACGTGGTTTTCACTACATTTACCT CACTGAAGAAGACTATTCACGTCT AAGCTCTTCAGTTATAGCCCATGA ACTGAAACTAGACAGCGGAGAAA CCAGATGGATTGTTGATACCATTG TTGGGAAAGAGGATGGACTTGGT TGTGAGAATCTGCATGGTAGTGGT GCCATTGCCAGTGCCTTTGCTAAG GCATATAGAGAGACCTTTACTCTG ACATTTGTGACTGGAAACGCAGTT GGAATTGGGGCTTATCTTGCTCG GCTAGGAATGCGGTGTATACAGC GACTTGATCAATCAATTCTTTTAAC TGGTTTTTCTGCCCTGAACAAACT TCTGGGGCGCGAGGTTTATAGCT CTCAGATGCAACTGGGTGGCCCC AAAATTATGGGTACAAATGGAGTC GTCCATCTGACAGTGCCAGATGAT CTTGAAGGTGTTTCTGCTATCTTG AAATGGCTCAGCTATGTTCCTGCC TATGTTGGCGGTCCTCTTCCTATT CTGAAGCCTCTTGATCCACCAGAT AGAGCTGTAACATATTTCCCAGAG AATTCATGTGATGCCCGTGCAGC CATCTGTGGGATTCAGGACACTCA AGGCAAGTGGTTGGGTGGTATGT TTGACAGAGAAAGCTTTGTGGAAA CATTAGAAGGATGGGCAAAAACT GTTATTACTGGAAGGGCAAAGCT GGGTGGGATTCCAGTTGGCGTCA TAGCAGTGGAAACCCAGACAATG ATGCAAGTAATCCCTTCTGACCCT GGTCAGCTTGATTCCGCTGAGCG TGTAGTCCCTCAAGCAGGACAGG TGTGGTTCCCAGATTCGGCCTCAA AAACAGCGCAGGCGTTGCTGGAT TTCAACCATGAAGGGCTCCCATTG TTCATACTTGCTAACTGGAGAGGC TTCTCTGGTGGGCAAAGGGATCT GTTTGAAGGAATCCTTCAGGCTG GCTCTACAATTGTTGAGAACCTGA GGACCTACAAGCAGCCAGCTTTT GTGTACATCCCAAAGGCTGGAGA GCTGCGTGGAGGTGCATGGGTTG TGGTGGACAGCAAGATCAATCCT GAGCACATTGAGATGTATGCGGA GAGGACTGCAAAGGGAAATGTCC TTGAGCCAGAAGGGCTGATTGAG ATTAAATTTAAGCCAAAAGAAGTG GAAGAGAGTATGATAAGGCTTGA CCCTGAGCTGGCCAGCCTTGATT CTAGACTCAAAGAAATGAAGAAAG CAAATGCTAGCCTGCAGGAAACG GAGGCCATCAACAGGAGCATCAA CAACCGGATAAAGAAGCTGATGC CCATCTATACGCAGGTTGCCACAC GGTTTGCTGAATTGCACGACACCT CTTCCAGAATGACTGCCAAAGGT GTGATCAGTAAGGTGGTTGATTG GGAGGAGTCTCGGAGCTTCTTCT ACAGGAGGTTGCGAAGGCGGGTC GCGGAGGATTCCCTTGCCCAGGA AGTTAAAGAAGCCGCTGGTGAGC CGATGCCTCACAGAGCAGCACTG GAGCGTATCAAGCAGTGGTATCT GGCCTCCAAGGGTTCCGAAGGAG ACGGTGAGAAGTGGAACGATGAC GAGGCTTTCTTCGCCTGGAAAGA CGATGCCAAGAACTACGAGAACC ATCTTCAGGAGTTGAAGGCTGAAA GAGTATCTAGACTGTTCTCGGATC TTGCTGAAAGCTCGGACGTGAAG GCCTTGCCCAACGGTCTTTCEGCG CCTCCTTGGCAAAGTA-
AGTTCTGCTTCTTCTTTTCITA Lolium gD- 3198 CTAGTTCTTGACTCGAGAAGAAGG multiflo- | NA- TCTGCAGCCAGCAGCCTCGTTCEG rum Con- TTAACTCGGCGAGCAAAGGAAAC tig AAGGTAAACACACGATCCTGGCA
AACACTTTTCTTTCTTCTCTGAATT GAAGTCGTCGATATCGTGATGTTT CATCTTCGTTACAATAAGCTTGGA TGACGGGGAGGGTACTTGCGTTG GCTAGGCAGTCGTTTCGACAAAG CTGGTGGTGGTGTGTCAACTCCA AAAGCCAACCTGCTTTTCGTTTCOT GGCAACAACCCTCCCCTGTTCAAA AACCTTGTCCTGTCAAATCCCAGC TTGCCGAAACGTCCTACTGCTGG CACCCCTTGTACCTCTTGTTCTAG GTTTGATCAAAGTTGATCTTTGTC AAATTTTACTAGATTTTTTTTACAT CTATACAACATATTTGTACAGTAC ATGTGCATACCGATCGATATAATT TTGTTGGTGCTCGCAGAGTTTGAC TAGCATGTAGCAGGAGCAGTGAT TTATGCTACTACTACTTATTGTACT CCAGTAGGATCTACAATAGTACTA GTATCGTAGTCGTCGAATTTAGTC AGTGGTAGCAAACACCAAACAGC GAGCAGAGAACGTCGCCTTCGCC GCCGTGATGCTGCTGGETTEGÇEGÇ GTTTAGCTCAGCTACCTCCCAACT AATTCCATCCTTCCCCAAATCAAA TAAAAAAGAAAAGAAAATAAATAA AACCAGTCCACCCCACAGTCCAA ATCCAAGTCCCAAGTCCCAACCCA GCTCCTCTCGCTCACGCCTTCCG GCCTCCCTCTCTACCCCGTCCCOG TGTTCCGGCCCCAGCCGAGCGTC GCATGGCGGGGCCEGCCGGTÇEGCÇ ACGGCAGTTATAAGCCGCGCGCGÇ GCCAACCATCCAGCGAGAGCACA GCACAGTAGCATAGCTACCTCGC AGCACGCCCTCCCTCCCTGCTAG CTACTCCTCCTCTGCAGACTGCAG CEGGECTEGEGEGGAGAGGAGGCGCG
CATTTAAGCCCGGCCTCCTCACCT GTCGGCCTGCCGCCGCGCCoGA
CGCCGAGGCCTTCCCTTCCCGGA TCTTGATCTGCCCGCCTTCCOTCCOT CCTCGGCGGCATTCEGTCGAACG GGCGGCGCGCGCCTACGGCAGT
ACGGTACCTACCCTGCCTTCTCTC CCCCCATCTCCCeTtTGCTCGCCGST
GTACGCGCCAGCGTTGGGCACCOC CGCACAAATCTACCACACAATTTC GCTCTCCCEGGCTCAGTCAGTCEG CCGCTGTGCGTAGATCGCTTCCA CTTCCTGCTGGGCGCTCCTGGAC GTTCCGTCGAGCGGTTTCTGAGA TTGGGCTGAGGGGATCATACCGG CTTCCTTTTCTGTCCTCTTTTCTGT TCCGTTGCGTGCAGGAATTGTTGT CTGCTCCCACGCCTTTGCTTGCTC ACCTATTCCGTGGACTCCCCTGTG ATCACAACATACTCAGCATACTTT TTCTTCACATGCCTAGGATAATGA AATCGCAATCTATGTACCATCGCT GTCGCGATTTCTGCTGGCTGTTGA CTACTAATTTTACCCCTTCACTTGT GTACTTATCCTCGTACCGCTGCTT GAGGAATTTCATATTTGGCTGCTT GAGGAATTTCATAAATCTGGCTAG ACACTCTTCATGTTTTTGTTCTTAC ATCTAGTAGTAGTTCAGAAAGAGG AAGCACAGACGAGCAACTGACGT ATCCGTGCAATTGTTCGCTAGTCA GAATGACAGAATCGACGTGCTCAT TTATATACCTGATGTAATTGTGCG CTTCTCCTCAAGCCGTAGCTTGAG GCGTTTCATTTITGTTCGTTTGCGA AAAGTTTGATGAGGAATTTCATGG TCTGGCTACGTACTCACCTTGTTT GTTTGCATCATTTTAGCATCAAGT TCAGAAACAATAAATACCCTACTT GTGCAATCATTCGCTAACAGAATC GACAATGCTAACGGTTTTTCTGTC CGTTGCTTGTCCAGCGCTGAAGG CTAGAGGGCGGCGACAATGGTGEG CGGAACCGGACAAGACAAATGGG ACGCCCAACAGGATGTCCAGTAA CAGGCACCTGTCCTCGCCGTCCOG TGGTCGACGAGTTCTGCAAGGCG CTCGGGGGCGATTCGCCCATCCA CAGCGTCCTGGTCGCCAACAATG GAATGGCCGCCGTCAAGTTCATG CGCAGCATCCGCACCTGGGCCCT CGAGACGTTTGGGACCGAGAAGG CCATTCTCCTGGTGGCCATGGCA ACTCCGGAGGACCTCAGGATAAA CGCCGAGCACATAAGGATCGCCG ACCAGTTCTTGGAAGTCCCTGGC GGAACAAACAATAACAATTATGCG AATGTGCAGCTCATTGTGGAGGTT AGCACGACGACCATTCTCCCGGT CCTTTTTACTAGCTTGTTGATTTAG CGTATCCATGTTTCTTGTGCTGGA TATTTGACTAGTTACTTAATGTTTC TACCTTCACTGTCACAGATAGCGG AGAGAACTCGGGTTTCTGCGGTTT GGCCTGGCTGGGGCCATGCTTCT GAGAACCCGGAACTTCCAGACGC GCTCAAGGAGAAGGGAATCATTTT TCTTGGGCCACCATCAGCCGCGA TGGCTGCACTTGGTGATAAGATTG GTTCTTCTCTTATTGCGCAAGCAG CAGGAGTTCCGACTCTTCCATGG AGTGGATCACATGTATACGTTCTT CTATTTCTGTATAGTTTTGCTCCTC TTTTTTITATCGGCTGCTATGTTGCT TAAAATTAAATCCAAATCAACTGTA GGTGAAAGTTCCGCAAGAAACCT GCCACTTGATACCTGAGGACATCT ATAAGAAAGCTTGTGTTACAACTA CGGAGGAAGCGGTGGCTAGTTGT CAGGTGGTGGGGTATCCTGCAAT GATCAAGGCATCATGGGGTGGTGE GTGGTAAAGGAATAAGGAAGGTT GGTCTTCTTTTTAGTTCGACTCTA CCGCAATTATATGGAAAGTCTCTG TTCACAAACGATACATGGAAATGT CCACTGTCCATACAAAACGAAGCT AGGTTTCGGCAAATATTGTAGAAT AAACGAAAGATGATTTTGATGTCA TCCAAATGCTTTTTATAGGTCCAC AATGATGATGAGGTGAGAGCCTT GTTTAAGCAAGTGCAAGGAGAAG TCCCCGGATCACCTATATTTATCA TGAAGGTGGCATCTCAGGTGA-
TAAGTGATAACAGC Lolium gD- 511 CTAATAACTTATCTGTAAATACAG multiflo- | NA- GACAAAGTGAAATTAGAAGGTTAC rum Con- AGTGACATGAAATACAATCCATCG tig CGTGATCGCCAGTGGCACATTTA
CACACTGAACAGTGAAGATCCAAA ATCAAATGACCAAAGGATATTCCT TCGTACAGTTGTTAGACAGCCAAG TTTAACCAATGGGTTTTTGTTTGG AAGTATCGACAATGAAGTAGGCC GTTCTCAGGCCACATCGTCATTCA CATCTAACAGCATACTTAGATCAT TGATTGCAGCGCTAGAAGAAATAG AGTTACATGCTCATAATAAGGCCA TGAGTTCACGCCATTCCCACATGT ATCTGTGCATGTTGAGAGAACAAC GGTTGTCTGATCTAATTCCATTTT CAAGGTCAGTCAAAATATACTTAT GTTCTCAATAAAATACACTGCATT AAATGTGCTCATAGATGCTCACTT GGTTTGTGCTTCTCATGGTGTTAG GATGATGGGTGAAGTTGGTCAA-
GATGAGGAGAT 991 Lolium gD- 252 TTCTCTGTAGAGCCGACATCTAGA multiflo- | NA- GGTTCAGCTGCTCTGTGACAAACA rum Con- CGGCAATGTAGCAGCACTGCACA tig GTCGAGACTGTAGTGTTCAAAGAA
GGCACCAAAAGGTTAGAAATTCTC CTGAAAAGTTATGTTGTCCAATAT CAGTTTCCTTGGAGCTAATACATG CCGAAACATTGTATACTGAGTACT GGTAGAAGTTCTGTAGCTTTAGGG ATTGGCAAAGTGCTAAACTCTG-
CAGAAGCTATACAAA 92 Sorghum |cD- 1913 CTCACAGATGTATCTGTGCTTACT halepen- | NA- GAGAGAACAACAATTGCATGAACT se Con- AATTCCATTTTCAAGGATGACTGA tig TGAAATTGATCAGGATGAAGGAAC
TGCATGTACACTTTTGAAGCATAT GGTATTGAATTTATATGAACATGTT GGGGTCAGGATGCATCGTCTTTC TGTGTGCCAGTGGGAAGTCAAGC TCTGGTTGGTTTGTGATGGGCAA GCTAGTGGTGCTTGGAGAGTTGT TGTTACCAATGTTACTGGTCACAC CTGCACCATTGATATTTACCGAGA AGTGGAAGACCCCAGCACACATC AGCTTCTCTACCACTCTGCCACAG CCACGGCTGGTCCTTTGCATGGT GTTGCATTGAATGAACCATACAAG CCTTTGGACGCTATTGACCTCAAA CGTTATGCTGCTAGGAAAAATGAA ACCACATACTGCTACGATTTCCCC TTGGCATTTGAAACAGCGCTGAAG AGATTATGGAAATCAAGTAGCTAT GGTGTTAGTGAAGCTAATGAGCG CAATCAACTCTATGCTGAAGTGAA AGAGCTTATATTTGTTGATTCGGA TGGAGCATGGGGCACTCCATTGG TTTCATTTGAACGCCCTCCAGGCA TCAATGATATTGGCATTGTTGCTT GGAACATGAAGCTGTCCACGCCA GAATTCCCAAGTGGCCGGGAGAT TATAGTTGTTGCCAATGATGTGAC ATTTAAAGCTGGGTCCTTTGGTCC AAGAGAAGATGCATTTITTTGATGC TGTTACCAATCTTGCCTGTGAGAG GAAACTTCCTCTTATCTATCTGGC AGCAACTGCTGGTGCCAGGCTTG GTGTAGCTGAGGAAATAAAGTCAT GCTTCCATGTCGGCTGGTCTGAT GATGAGAGCCCTGAACGTGGTTT TCAGTACATTTACCTCACTACACA AGATTATTCACGTCTAAGCTCTTC AGTAATAGCTCACGAGCTGCAACT AGAAAATGGAGAAACCAGATGGG TGGTTGATACCATTGTTGGTAAAG AGGATGGACTTGGTTGTGAGAAT CTCCATGGAAGTGGTGCGATTGC CAGTGCATATTCCAAGGCATACAA AGAGACCTTTACTCTGACATTTGT GACTGGAAGAGCTGTTGGCATTG GGGCTTATCTGGCTCGTTTAGGTA TGAGGTGTATACAACGTCTTGATC AACCAATTATTCTGACTGGGTTTT CTGCACTAAACAAGCTTCTGGGG CGGGAGGTGTACAGTTCTCATAT GCAATTGGGTGGCCCCAAAATCA TGGCTACAAATGGTGTTGTCCACC AAACTGTGTCAGATGACCTTGAAG GTGTTTCTGCTATCCTGAAATGGC TCAGTTATGTTCCTCCATATGTTG GTGGTCCTCTTCCCATTATGAAAC CCCTGGACCCACCCGAAAGACCA GTAGCATACTTCCCTGAGAATGCT TGTGATGCTCGTGCAGCCATCTGT GGCATTCAAGACGGTGAAGGGAA GTGGTTAGGTGGTATGTTTGATAG GGAAACCTTCGTGGAAACATTGG AAGGTTGGGCAAAAACAGTTATCA CCGGAAGAGCAAAGCTTGGTGGA ATACCAGTTGGTGTCATAGCTGTG GAAACCCAGACTGTGATGCAAGT CATCCCAGCTGATCCAGGTCAGC TTGATTCCGCTGAGCGTGTAGTCC CTCAAGCAGGTCAGGTGTGGTTC CCAGATTCTGCAGCCAAAACAGCT CAGGCATTAATGGATTTCAACCGT GAGGAGCTTCCACTGTTCATCCTT GCAAACTGGAGAGGTTTCTCTGG TGGGCAAAGGGATTTATTTGAAGG AATCCTTCAGGCTGGTTCAACAAT TGTTGAGAATCTGAGGACGTACAA GCAGCCTGCTTTTGTATATATCCC AATGGGTGGAGAGCTACGGG

Claims (15)

REIVINDICAÇÕES
1. Método de controle de planta caracterizado pelo fato de que compreende: tratar uma planta com uma composição compreen- dendo um polinucleotídeo e um agente de transferência, em que o re- ferido polinucleotídeo é essencialmente idêntico ou essencialmente complementar a uma sequência do gene ACCase ou fragmento da mesma, ou a um transcript de RNA da referida sequência do gene ACCase ou fragmento da mesma, em que a referida sequência do ge- ne ACCase é selecionada do grupo constituído pela SEQ ID nº: 1-92 ou um fragmento de polinucleotídeo da mesma, da onde referida ca- pacidade de crescimento ou de desenvolvimento ou reprodutora de planta é reduzida ou referida planta é mais sensível a um herbicida inibidor de ACCase em relação a uma planta não tratada com referida composição.
2. Método, de acordo com a reivindicação 1, caracterizado pelo fato de que (i) o referido agente de transferência é uma composição de tensoativo de organossilicone ou composto contido nele, ou (ii) a referida planta é selecionada do grupo constituído por Amaranthus palmeri, Amaranthus rudis, Amaranthus chlorostachys, Amaranthus thunbergii, Amaranthus graecizans, Amaranthus hybridus, Amaranthus lividus, Amanaranthus spinosus, Abutilon theophrasti, Ambrosia trifida, Commelina diffusa, Conyza candensis, Lolium muilti- florum, Sorghum halepense, Xanthium strumarium, Euphorbia hete- rophylla, Kochia scoparia e Digitaria sanguinalis, ou (iii) a referida composição adicionalmente compreende refe- rido herbicida inibidor de ACCase e aplicação externa a uma planta com referida composição, de preferência a referida composição adici- onalmente compreendendo um ou mais herbicidas diferentes do refe- rido herbicida inibidor de ACCase;
(iv) o referido fragmento de polinucleotídeo é 18 contíguos, 19 nucleotídeos contíguos, 20 nucleotídeos contíguos ou pelo menos 21 nucleotídeos contíguos em comprimento e pelo menos 85 por cento idêntico a uma sequência do gene ACCase selecionada do grupo constituído pela SEQ ID nº: 1-92, sendo que preferencialmente (a) o referido fragmento de polinucleotídeo é selecionado do grupo constituído por sSDNA ou ssRNA senso ou anti-senso, dsR- NA, ou dsDNA, ou híbridos de dsDNA/RNA, ou (b) a referida composição compreende qualquer combina- ção de dois ou mais dos referidos fragmentos de polinucleotídeo e aplicação externa a uma planta com referida composição.
3. Composição caracterizada pelo fato de que compreen- dendo um polinucleotídeo e um agente de transferência, em que o re- ferido polinucleotídeo é essencialmente idêntico ou essencialmente complementar a uma sequência do gene ACCase ou a um transcript de RNA da referida sequência do gene ACCase, em que a referida se- quência do gene ACCase é selecionada do grupo constituído pela SEQ ID nº: 1-92 ou um fragmento de polinucleotídeo da mesma e da onde uma planta tratada com referida composição tem sua capacidade de crescimento ou de desenvolvimento ou reprodutora regulada, su- primida ou retardada ou referida planta é mais sensível a um herbicida inibidor de ACCase como um resultado da referida composição con- tendo polinucleotídeo em relação a uma planta não tratada com referi- da composição.
4. Composição, de acordo com a reivindicação 3, caracte- rizada pelo fato de que (i) o referido agente de transferência é uma composição de organossilicone, ou (ii) o referido fragmento de polinucleotídeo é 18 contíguos,
19 nucleotídeos contíguos, 20 nucleotídeos contíguos ou pelo menos 21 nucleotídeos contíguos em comprimento e pelo menos 85 por cento idêntico a uma sequência do gene ACCase selecionada do grupo constituído pela SEQ ID nº: 1-92, ou (iii) o referido polinucleotídeo é selecionado do grupo cons- tituído pela SEQ ID no: 93-3900, ou (iv) o referido polinucleotídeo é selecionado do grupo constituí- do pela SEQ ID no: 3901-4530, ou (v) a dita composição adicionalmente compreende um herbicida inibidor de AC- Case, sendo que preferencialmente (a) a referida molécula inibidora de ACCase é selecionada do grupo constituído por ariloxifenoxipropionatos, ciclo-hexanodionas e fenilpirazolina, ou (b) a composição adicionalmente compreende um herbicida inibidor de não- ACCase.
5. Método de redução de expressão de um gene ACCase em uma planta caracterizado pelo fato de que compreende: aplicação externa a uma planta de uma composição compreendendo um polinu- cleotídeo e um agente de transferência, em que o referido polinucleo- tídeo é essencialmente idêntico ou essencialmente complementar a uma sequência do gene ACCase ou fragmento da mesma, ou ao transcript de RNA da referida sequência do gene ACCase ou fragmen- to da mesma, em que a referida sequência do gene ACCase é seleci- onada do grupo constituído pela SEQ ID nº: 1-92 ou um fragmento de polinucleotídeo da mesma, da onde referida expressão do referido ge- ne ACCase é reduzida em relação a uma planta na qual a composição não foi aplicada.
6. Método, de acordo com a reivindicação 5, caracterizado pelo fato de que (i) o referido agente de transferência é uma composição de organossilicone, (ii) o referido fragmento de polinucleotídeo é 19 nucleotídeos contíguos, 20 nucleotídeos contíguos ou pelo menos 21 nucleotídeos contíguos em comprimento e pelo menos 85 por cento idêntico a uma sequência do gene ACCase selecionada do grupo constituído pela SEQ ID nº: 1-92, ou (iii) a referida molécula de polinucleotídeo é selecionada do grupo constituído por sSDNA ou ssRNA senso ou anti-senso, dsRNA, ou dsDNA, ou híbridos de dsDNA/RNA.
7. Cassete de expressão microbiana caracterizado pelo fa- to de que compreende um fragmento de polinucleotídeo de 18 contí- guos, 19 nucleotídeos contíguos, 20 nucleotídeos contíguos ou pelo menos 21 nucleotídeos contíguos em comprimento e pelo menos 85 por cento idêntico a uma sequência do gene ACCase selecionada do grupo constituído pela SEQ ID nº: 1-92.
8. Método para fazer um polinucleotídeo caracterizado pe- lo fato de que compreende a) transformar o cassete de expressão mi- crobiana conforme definido na reivindicação 7 em um micróbio; b) cul- tivar referido micróbio; c) colher um polinucleotídeo de referido micró- bio, em que o referido polinucleotídeo é 18 contíguos, 19 nucleotídeos contíguos, 20 nucleotídeos contíguos ou pelo menos 21 nucleotídeos contíguos em comprimento e pelo menos 85 por cento idêntico a uma sequência do gene ACCase selecionada do grupo constituído pela SEQ ID nº: 1-92.
9. Método de identificação de polinucleotídeos úteis na mo-
dulação de expressão do gene ACCase quando externamente tratan- do uma planta caracterizado pelo fato de que compreende: a) prover uma pluralidade de polinucleotídeos que compreendem uma região essencialmente idêntica ou essencialmente complementar a um frag- mento de polinucleotídeo de 18 contíguos, 19 nucleotídeos contíguos, nucleotídeos contíguos ou pelo menos 21 nucleotídeos contíguos em comprimento e pelo menos 85 por cento idêntico a uma sequência do gene ACCase selecionada do grupo constituído pela SEQ ID nº: 1- 92; b) tratar externamente referida planta com um ou mais dos referi- dos polinucleotídeos e um agente de transferência; c) analisar referida planta ou extrato para modulação da expressão do gene ACCase, e , da onde uma planta tratada com referida composição tem sua capaci- dade de crescimento ou de desenvolvimento ou reprodutora regulada, suprimida ou retardada ou referida planta é mais sensível a um herbi- cida inibidor de ACCase como um resultado da referida composição contendo polinucleotídeo em relação a uma planta não tratada com referida composição.
10. Método, de acordo com a reivindicação 9, caracteriza- do pelo fato de que (i) a referida planta é selecionada do grupo constituído por Amaranthus palmeri, Amaranthus rudis, Amaranthus chlorostachys, Amaranthus thunbergii, Amaranthus graecizans, Amaranthus hybridus, Amaranthus lividus, Amanaranthus spinosus, Abutilon theophrasti, Ambrosia trifida, Commelina diffusa, Conyza candensis, Lolium multi- florum, Sorghum halepense, Xanthium strumarium, Euphorbia hete- rophylla, Kochia scoparia e Digitaria sanguinalis, ou (ii) .
a referida expressão de gene ACCase é reduzida em rela- ção a uma planta não tratada com referido fragmento de polinucleotí- deo e um agente de transferência, ou
(ili) o referido agente de transferência é um composto de organossilicone.
11. Composição química agrícola caracterizada pelo fato de que compreende uma admistura de um polinucleotídeo e um inibi- dor de ACCase e um co-herbicida, em que o referido polinucleotídeo é essencialmente idêntico ou essencialmente complementar a uma por- ção de uma sequência do gene ACCase, ou a uma porção de um transcript de RNA da referida sequência do gene ACCase, em que a referida sequência do gene ACCase é selecionada do grupo constituí- do pela SEQ ID nº: 1-92 ou um fragmento de polinucleotídeo da mes- ma, e da onde uma planta tratada com referida composição tem sua capacidade de crescimento ou de desenvolvimento ou reprodutora re- gulada, suprimida ou retardada ou referida planta é mais sensível a um herbicida inibidor de ACCase como um resultado da referida composi- ção contendo polinucleotídeo em relação a uma planta não tratada com referida composição.
12. Composição química agrícola, de acordo com a reivin- dicação 11, caracterizada pelo fato de que o referido co-herbicida é selecionado do grupo constituído por herbicidas de amida, herbicidas arsenicais, herbicidas de benzotiazol, herbicidas de benzoilciclo- hexanodiona, herbicidas de benzofuranil alquilsulfonato, herbicidas de ciclo-hexeno oxima, herbicidas de ciclopropilisoxazol, herbicidas de dicarboximida, herbicidas de dinitroanilina, herbicidas de dinitrofenol, herbicidas de difenil éter, herbicidas de ditiocarbamato, herbicidas de glicina, herbicidas halogenados alifáticos, herbicidas de imidazolinona, herbicidas inorgânicos, herbicidas de nitrilo, herbicidas de organofósfo- ro, herbicidas de oxadiazolona, herbicidas de oxazol, herbicidas de fe- nóxi, herbicidas de fenilenodiamina, herbicidas de pirazol, herbicidas de piridazina, herbicidas de piridazinona, herbicidas de piridina, herbi- cidas de pirimidinadiamina, herbicidas de pirimidiniloxibenzilamina,
herbicidas de amônio quaternário, herbicidas de tiocarbamato, herbici- das de tiocarbonato, herbicidas de tioureia, herbicidas de triazina, her- bicidas de triazinona, herbicidas de triazol, herbicidas de triazolona, herbicidas de triazolopirimidina, herbicidas de uracil, e herbicidas de ureia.
13. Composição química agrícola caracterizada pelo fato de que compreende uma admistura de um polinucleotídeo e um herbi- cida inibidor de ACCase e um pesticida, em que o referido polinucleo- tídeo é essencialmente idêntico ou essencialmente complementar a uma porção de uma sequência do gene ACCase, ou a uma porção de um transcript de RNA da referida sequência do gene ACCase, em que a referida sequência do gene ACCase é selecionada do grupo consti- tuído pela SEQ ID nº: 1-92 ou um fragmento de polinucleotídeo da mesma, da onde um campo de plantas de cultivo em necessidade de controle de ervas daninhas e peste são tratadas com referida compo- sição, e da onde uma planta tratada com referida composição tem sua capacidade de crescimento ou de desenvolvimento ou reprodutora re- gulada, suprimida ou retardada ou referida planta é mais sensível ao dito herbicida inibidor de ACCase como um resultado da referida com- posição contendo polinucleotídeo em relação a uma planta não tratada com referida composição.
14. Composição química agrícola, de acordo com a reivin- dicação 13, caracterizada pelo fato de que o referido pesticida é sele- cionado do grupo consistindo em inseticidas, fungicidas, nematocidas, bactericidas, acaricidas, reguladores de crescimento, quimioesterili- zantes, semioquímicos, repelentes, atrativos, feromônios, estimulantes de alimentação e biopesticidas.
15. Composição de herbicida caracterizada pelo fato de que compreende um herbicida inibidor de ACCase e um polinucleotí- deo e um agente de transferência, em que o referido polinucleotídeo é selecionado do grupo constituído pela SEQ ID no: 4538 ou um com- plemento ou fragmento de polinucleotídeo da mesma, e da onde uma planta tratada com referida composição tem sua capacidade de cres- cimento ou de desenvolvimento ou reprodutora regulada, suprimida ou retardada ou referida planta é mais sensível a um herbicida inibidor de ACCase como um resultado da referida composição contendo polinu- cleotídeo em relação à uma planta não tratada com referida composi- ção.
| 180 + i | 160 - : | Í 140 SS Í | É 120 O Í E | o 1 ; go o | | & So O Í = Í SS Í 32 60 PO i z i DO Í ao A Í | 20 + o | o — AL... MI... JN... MIA... AO... JN.
Nãotratada —Tampão —ssDNA-ACCasessDNA-ACCase —Tampãofb — Cletodim = | Í fbCletodim — Cletodim Í ! :
Figura 1
BR112014005958-6A 2011-09-13 2012-09-12 métodos e composições químicas agrícolas para controle de planta, método de redução de expressão de um gene accase em uma planta, cassete de expressão microbiana, método para fazer um polinucleotídeo, método de identificação de polinucleotídeos úteis na modulação de expressão do gene accase e composição herbicida BR112014005958A2 (pt)

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UY34330A (es) 2013-04-30
MX343072B (es) 2016-10-21
AR087956A1 (es) 2014-04-30
WO2013040033A8 (en) 2013-06-20
MX362810B (es) 2019-02-13
MX2014003071A (es) 2014-07-17
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CN104160028A (zh) 2014-11-19
WO2013040033A1 (en) 2013-03-21
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