BR0110667A - Processo para a preparação de um composto, e, composto - Google Patents

Processo para a preparação de um composto, e, composto

Info

Publication number
BR0110667A
BR0110667A BR0110667-8A BR0110667A BR0110667A BR 0110667 A BR0110667 A BR 0110667A BR 0110667 A BR0110667 A BR 0110667A BR 0110667 A BR0110667 A BR 0110667A
Authority
BR
Brazil
Prior art keywords
compound
keto
preparation
group
primary hydroxy
Prior art date
Application number
BR0110667-8A
Other languages
English (en)
Inventor
Robert Antony Holt
Andrew John Blacker
Christopher David Reeve
Original Assignee
Avecia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Ltd filed Critical Avecia Ltd
Publication of BR0110667A publication Critical patent/BR0110667A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE UM COMPOSTO, E, COMPOSTO". Um processo é fornecido para a preparação de um composto da Fórmula (1) Fórmula 1 em que R e R' representam grupos hidrocarbila opcionalmente substituídos e X representa um grupo de ligação de hidrocarbila. O processo compreende tanto a redução estereoseletiva do grupo ceto em um precursor diidróxi ceto seguida pela esterificação seletiva de um hidróxi primário, quanto a esterificação seletiva de um hidróxi primário de um precursor de diidróxi ceto seguida pela redução estereoseletiva do grupo ceto.
BR0110667-8A 2000-05-09 2001-05-01 Processo para a preparação de um composto, e, composto BR0110667A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0011120.3A GB0011120D0 (en) 2000-05-09 2000-05-09 Process
PCT/GB2001/001915 WO2001085975A1 (en) 2000-05-09 2001-05-01 Process for the preparation of dihydroxy esters and derivatives thereof

Publications (1)

Publication Number Publication Date
BR0110667A true BR0110667A (pt) 2003-03-25

Family

ID=9891211

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0110667-8A BR0110667A (pt) 2000-05-09 2001-05-01 Processo para a preparação de um composto, e, composto

Country Status (34)

Country Link
US (4) US7157255B2 (pt)
EP (3) EP1282719B1 (pt)
JP (1) JP4733901B2 (pt)
KR (2) KR100914675B1 (pt)
CN (1) CN1196793C (pt)
AR (2) AR028074A1 (pt)
AT (3) ATE458823T1 (pt)
AU (2) AU5238301A (pt)
BR (1) BR0110667A (pt)
CA (2) CA2408004C (pt)
CY (3) CY1105376T1 (pt)
CZ (3) CZ302674B6 (pt)
DE (3) DE60141424D1 (pt)
DK (3) DK1282719T3 (pt)
EE (1) EE05062B1 (pt)
ES (3) ES2340190T3 (pt)
GB (1) GB0011120D0 (pt)
HK (3) HK1051708A1 (pt)
HU (1) HUP0302216A3 (pt)
IL (4) IL152608A0 (pt)
IS (1) IS2290B (pt)
MX (1) MXPA02010955A (pt)
MY (1) MY127751A (pt)
NO (1) NO20025377L (pt)
NZ (1) NZ522407A (pt)
PL (3) PL208379B1 (pt)
PT (3) PT1282719E (pt)
RU (1) RU2266961C2 (pt)
SI (3) SI1282719T1 (pt)
SK (2) SK286746B6 (pt)
TW (1) TWI240753B (pt)
UA (1) UA73774C2 (pt)
WO (1) WO2001085975A1 (pt)
ZA (1) ZA200208937B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011120D0 (en) * 2000-05-09 2000-06-28 Avecia Ltd Process
AU6269201A (en) * 2000-06-05 2001-12-17 Kaneka Corporation Process for preparing optically active 2-(6-(hydroxy-methyl)-1,3-dioxan-4-yl)acetic acid derivatives
NL1015744C2 (nl) * 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
EP1417180B1 (en) 2001-07-13 2006-12-27 AstraZeneca UK Limited Preparation of aminopyrimidine compounds
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
GB0211751D0 (en) * 2002-05-22 2002-07-03 Avecia Ltd Compound and process
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US8093306B2 (en) * 2010-12-22 2012-01-10 Rentech, Inc. Integrated biorefinery for production of liquid fuels
CN102373250B (zh) * 2011-11-08 2012-08-22 张家港市信谊化工有限公司 阿伐他汀钙侧链中间体的制备方法
CN102618596A (zh) * 2012-03-20 2012-08-01 中国药科大学 一种非水相体系中生物转化制备关附庚素的方法
WO2014203045A1 (en) 2013-06-20 2014-12-24 Lupin Limited A novel, green and cost effective process for synthesis of tert-butyl (3r,5s)-6-oxo-3,5-dihydroxy-3,5-o-isopropylidene-hexanoate
CN105503816B (zh) * 2016-02-17 2018-02-13 中节能万润股份有限公司 一种固体(4R‑cis)‑6‑甲酰基‑2,2‑二甲基‑1,3‑二氧己环‑4‑乙酸叔丁酯的制备方法
CN108530416B (zh) * 2017-11-02 2020-05-12 江苏阿尔法药业有限公司 一种瑞舒伐他汀中间体的制备方法
CN109574830B (zh) * 2019-01-04 2021-04-13 浙江宏元药业股份有限公司 一种瑞舒伐他汀钙中间体及其制备方法和应用
KR102384854B1 (ko) 2021-06-15 2022-04-11 한대성 풀빅산 및 일라이트를 이용한 침대

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NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
EP1417180B1 (en) * 2001-07-13 2006-12-27 AstraZeneca UK Limited Preparation of aminopyrimidine compounds
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Also Published As

Publication number Publication date
AU5238301A (en) 2001-11-20
CY1105376T1 (el) 2010-04-28
ATE330020T1 (de) 2006-07-15
AR070946A2 (es) 2010-05-19
DK1657310T3 (da) 2007-10-29
DE60129865D1 (de) 2007-09-20
KR100914675B1 (ko) 2009-08-28
HK1051708A1 (en) 2003-08-15
EP1657310B1 (en) 2007-08-08
EP1282719B1 (en) 2006-06-14
IL193404A (en) 2010-04-29
SK15892002A3 (sk) 2003-04-01
HK1096998A1 (en) 2007-06-15
CZ302674B6 (cs) 2011-08-24
DK1282719T3 (da) 2006-10-02
EP1726658A3 (en) 2008-12-24
JP4733901B2 (ja) 2011-07-27
HUP0302216A3 (en) 2011-03-28
US20060194297A1 (en) 2006-08-31
NZ522407A (en) 2004-06-25
PT1657310E (pt) 2007-09-26
KR20030032949A (ko) 2003-04-26
MXPA02010955A (es) 2003-05-27
PL208359B1 (pl) 2011-04-29
PT1282719E (pt) 2006-09-29
ES2289722T3 (es) 2008-02-01
KR100996977B1 (ko) 2010-11-26
IS6609A (is) 2002-11-07
PT1726658E (pt) 2010-04-15
CY1106910T1 (el) 2012-09-26
KR20080042129A (ko) 2008-05-14
US7416865B2 (en) 2008-08-26
DE60129865T2 (de) 2008-05-08
EP1282719A1 (en) 2003-02-12
US7888083B2 (en) 2011-02-15
CZ302675B6 (cs) 2011-08-24
SK287524B6 (sk) 2011-01-04
EE05062B1 (et) 2008-08-15
CZ302632B6 (cs) 2011-08-10
ZA200208937B (en) 2003-08-28
IL152608A (en) 2009-05-04
EP1726658B1 (en) 2010-02-24
IL193405A (en) 2010-04-29
ATE369437T1 (de) 2007-08-15
HK1090090A1 (en) 2006-12-15
NO20025377L (no) 2003-01-07
US7732171B2 (en) 2010-06-08
PL359336A1 (en) 2004-08-23
AR028074A1 (es) 2003-04-23
DE60141424D1 (de) 2010-04-08
CA2677945A1 (en) 2001-11-15
AU2001252383B2 (en) 2005-04-14
NO20025377D0 (no) 2002-11-08
SK286746B6 (sk) 2009-04-06
CN1196793C (zh) 2005-04-13
RU2266961C2 (ru) 2005-12-27
DE60120685T2 (de) 2007-06-14
ATE458823T1 (de) 2010-03-15
CY1109991T1 (el) 2014-09-10
DK1726658T3 (da) 2010-05-17
CN1440461A (zh) 2003-09-03
CA2408004A1 (en) 2001-11-15
EE200200628A (et) 2004-04-15
PL208379B1 (pl) 2011-04-29
IL193404A0 (en) 2009-02-11
CA2408004C (en) 2010-04-13
JP2003532427A (ja) 2003-11-05
HUP0302216A2 (hu) 2003-10-28
US20100209984A1 (en) 2010-08-19
US7157255B2 (en) 2007-01-02
US20080280336A1 (en) 2008-11-13
IL193405A0 (en) 2009-02-11
CZ20023675A3 (cs) 2003-02-12
WO2001085975A1 (en) 2001-11-15
EP1726658A2 (en) 2006-11-29
PL208377B1 (pl) 2011-04-29
SI1726658T1 (sl) 2010-05-31
UA73774C2 (en) 2005-09-15
TWI240753B (en) 2005-10-01
IS2290B (is) 2007-10-15
MY127751A (en) 2006-12-29
EP1657310A1 (en) 2006-05-17
DE60120685D1 (de) 2006-07-27
ES2264981T3 (es) 2007-02-01
IL152608A0 (en) 2003-06-24
SI1657310T1 (sl) 2007-12-31
GB0011120D0 (en) 2000-06-28
ES2340190T3 (es) 2010-05-31
SI1282719T1 (sl) 2006-10-31
US20030134900A1 (en) 2003-07-17

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