BG64127B1 - Противопаразитни пиразоли - Google Patents

Противопаразитни пиразоли Download PDF

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Publication number
BG64127B1
BG64127B1 BG103454A BG10345499A BG64127B1 BG 64127 B1 BG64127 B1 BG 64127B1 BG 103454 A BG103454 A BG 103454A BG 10345499 A BG10345499 A BG 10345499A BG 64127 B1 BG64127 B1 BG 64127B1
Authority
BG
Bulgaria
Prior art keywords
dichloro
cyano
halo
hydrogen
pyrazole
Prior art date
Application number
BG103454A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103454A (en
Inventor
Bernard J. Banks
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625290.3A external-priority patent/GB9625290D0/en
Priority claimed from GBGB9702235.4A external-priority patent/GB9702235D0/en
Priority claimed from GBGB9712045.5A external-priority patent/GB9712045D0/en
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of BG103454A publication Critical patent/BG103454A/xx
Publication of BG64127B1 publication Critical patent/BG64127B1/bg

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
BG103454A 1996-12-05 1999-06-01 Противопаразитни пиразоли BG64127B1 (bg)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9625290.3A GB9625290D0 (en) 1996-12-05 1996-12-05 Parasiticidal agents
GBGB9702235.4A GB9702235D0 (en) 1997-02-04 1997-02-04 Parasiticidal agents
GBGB9712045.5A GB9712045D0 (en) 1997-06-10 1997-06-10 Parasiticidal agents
PCT/EP1997/006697 WO1998024767A1 (en) 1996-12-05 1997-11-25 Parasiticidal pyrazoles

Publications (2)

Publication Number Publication Date
BG103454A BG103454A (en) 2000-01-31
BG64127B1 true BG64127B1 (bg) 2004-01-30

Family

ID=27268619

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103454A BG64127B1 (bg) 1996-12-05 1999-06-01 Противопаразитни пиразоли

Country Status (40)

Country Link
US (2) US6075043A (sr)
EP (1) EP0946515B1 (sr)
JP (2) JP3950483B2 (sr)
KR (1) KR100354311B1 (sr)
CN (1) CN1106386C (sr)
AR (1) AR013879A1 (sr)
AT (1) ATE233736T1 (sr)
AU (1) AU720705B2 (sr)
BG (1) BG64127B1 (sr)
BR (1) BR9713565A (sr)
CA (1) CA2273951C (sr)
CO (1) CO5031251A1 (sr)
CZ (1) CZ295295B6 (sr)
DE (1) DE69719547T2 (sr)
DK (1) DK0946515T3 (sr)
DZ (1) DZ2360A1 (sr)
EA (1) EA002278B1 (sr)
ES (1) ES2191870T3 (sr)
HK (1) HK1029111A1 (sr)
HR (1) HRP970663B1 (sr)
HU (1) HUP0000544A3 (sr)
ID (1) ID21556A (sr)
IL (1) IL129866A (sr)
IS (1) IS1982B (sr)
MA (1) MA24414A1 (sr)
MY (1) MY117021A (sr)
NO (2) NO992736D0 (sr)
NZ (1) NZ335611A (sr)
OA (1) OA11055A (sr)
PA (1) PA8442101A1 (sr)
PE (1) PE20199A1 (sr)
PL (1) PL190926B1 (sr)
PT (1) PT946515E (sr)
RS (1) RS49720B (sr)
SK (1) SK285203B6 (sr)
TN (1) TNSN97197A1 (sr)
TW (1) TW524667B (sr)
UA (1) UA60321C2 (sr)
UY (2) UY24798A1 (sr)
WO (1) WO1998024767A1 (sr)

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AR021608A1 (es) * 1998-12-11 2002-07-31 Merial Ltd Represion de artropodos en animales
GB9916052D0 (en) * 1999-07-08 1999-09-08 Pfizer Ltd Anthelmintic compositions
CO5261614A1 (es) 1999-12-02 2003-03-31 Aventis Cropsience S A Control de artropodos en animales
AU2003218758A1 (en) * 2002-03-14 2003-09-22 Syngenta Participations Ag Derivatives of 1-phenyl-3-phenylpyrazole as herbicides
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WO2005023773A1 (en) * 2003-09-04 2005-03-17 Pfizer Limited Process for the preparation of substituted aryl pyrazoles
US7514464B2 (en) 2003-12-18 2009-04-07 Pfizer Limited Substituted arylpyrazoles
GB0329314D0 (en) * 2003-12-18 2004-01-21 Pfizer Ltd Substituted arylpyrazoles
WO2005090313A1 (en) 2004-03-18 2005-09-29 Pfizer Limited N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides
CN101228134A (zh) 2005-06-15 2008-07-23 辉瑞有限公司 用作杀寄生虫剂的取代芳基吡唑
US7645786B2 (en) 2005-06-15 2010-01-12 Pfizer Inc. Substituted arylpyrazoles
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US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
CA2614282A1 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
EP1783114A1 (en) * 2005-11-03 2007-05-09 Novartis AG N-(hetero)aryl indole derivatives as pesticides
DE102006061537A1 (de) 2006-12-27 2008-07-03 Bayer Healthcare Ag Mittel zur Bekämpfung von Parasiten an Tieren
DE102006061538A1 (de) 2006-12-27 2008-07-03 Bayer Healthcare Ag Kombinationsprodukt zur Bekämpfung von Parasiten an Tieren
MX2012011549A (es) 2010-04-08 2013-01-29 Ah Usa 42 Llc Derivados de 3,5-difenil-isoxazolina sustituida como insecticidas y acaricidas.
EP2601190B1 (en) 2010-08-05 2018-07-04 Zoetis Services LLC Isoxazoline derivatives as antiparasitic agents
ES2793481T3 (es) 2010-09-24 2020-11-16 Zoetis Services Llc Oximas de isoxazolina como agentes antiparasitarios
RS54860B1 (sr) 2011-03-10 2016-10-31 Zoetis Services Llc Spirociklični derivati izoksazolina kao antiparazitska sredstva
CN103562190A (zh) 2011-03-22 2014-02-05 佐蒂斯有限责任公司 作为抗寄生虫药的异噁唑啉衍生物
BR112013033914A2 (pt) 2011-06-30 2016-11-22 Hansen Ab Gmbh agente para o controle de parasitas em animais e uso de um agente
PL2814825T3 (pl) 2012-02-03 2016-08-31 Zoetis Services Llc Dihydrofuranowe pochodne azetydyny jako środki przeciwpasożytnicze
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
JP6049866B2 (ja) 2012-05-09 2016-12-21 ゾエティス・サービシーズ・エルエルシー 駆虫剤としてのアゼチジン誘導体
WO2014093481A1 (en) 2012-12-12 2014-06-19 Zoetis Llc Phenylpyrazole injectable compositions
TWI762706B (zh) 2017-08-24 2022-05-01 丹麥商諾佛 儂迪克股份有限公司 Glp-1組成物及其用途
CN111116478B (zh) * 2019-12-18 2021-10-26 浙江金伯士药业有限公司 一种兽用抗生素维吉霉素中间体的制备方法
BR112022013795A2 (pt) 2020-02-18 2022-09-13 Novo Nordisk As Composição farmacêutica líquida, e, kit
CN115894374A (zh) * 2023-02-16 2023-04-04 广州佳途科技股份有限公司 一种氟甲腈的制备方法及其应用

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IE80657B1 (en) * 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
GR970100096A (el) * 1996-03-29 1997-11-28 Merial Εξωτερικη διαταξη κατα των παρασιτων για βοοειδη με βαση τη ν-φαινυλπυραζολη, ειδικα σκουλαρικια.
TW524667B (en) 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
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Also Published As

Publication number Publication date
HUP0000544A3 (en) 2002-01-28
HUP0000544A2 (hu) 2000-06-28
YU25299A (sh) 2002-10-18
TNSN97197A1 (fr) 2005-03-15
KR20000057432A (ko) 2000-09-15
PT946515E (pt) 2003-06-30
JP2000505812A (ja) 2000-05-16
UY24923A1 (es) 1998-09-01
NO992732L (no) 1999-08-05
MY117021A (en) 2004-04-30
ATE233736T1 (de) 2003-03-15
SK285203B6 (sk) 2006-08-03
TW524667B (en) 2003-03-21
IL129866A0 (en) 2000-02-29
UY24798A1 (es) 2000-09-29
MA24414A1 (fr) 1998-07-01
CA2273951C (en) 2003-04-01
CO5031251A1 (es) 2001-04-27
CZ295295B6 (cs) 2005-06-15
PL190926B1 (pl) 2006-02-28
NO313518B1 (no) 2002-10-14
ID21556A (id) 1999-06-24
OA11055A (en) 2002-03-07
WO1998024767A1 (en) 1998-06-11
AR013879A1 (es) 2001-01-31
IS1982B (is) 2005-01-14
BG103454A (en) 2000-01-31
PL333922A1 (en) 2000-01-31
JP3950483B2 (ja) 2007-08-01
DE69719547T2 (de) 2003-10-02
AU5485998A (en) 1998-06-29
RS49720B (sr) 2007-12-31
DE69719547D1 (de) 2003-04-10
CN1106386C (zh) 2003-04-23
ES2191870T3 (es) 2003-09-16
JP2007211016A (ja) 2007-08-23
KR100354311B1 (ko) 2002-09-28
CZ195199A3 (cs) 2000-08-16
HRP970663A2 (en) 1998-10-31
HK1029111A1 (en) 2001-03-23
EA199900447A1 (ru) 2000-02-28
DZ2360A1 (fr) 2002-12-28
US6075043A (en) 2000-06-13
CN1258282A (zh) 2000-06-28
NO992736D0 (no) 1999-06-04
NZ335611A (en) 2001-01-26
DK0946515T3 (da) 2003-07-14
NO992732D0 (no) 1999-06-04
EA002278B1 (ru) 2002-02-28
EP0946515A1 (en) 1999-10-06
UA60321C2 (uk) 2003-10-15
IS5050A (is) 1999-05-11
HRP970663B1 (en) 2003-10-31
PA8442101A1 (es) 2000-05-24
AU720705B2 (en) 2000-06-08
CA2273951A1 (en) 1998-06-11
SK74099A3 (en) 2001-02-12
BR9713565A (pt) 2000-03-14
US6268509B1 (en) 2001-07-31
EP0946515B1 (en) 2003-03-05
PE20199A1 (es) 1999-03-05
IL129866A (en) 2004-05-12

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