BG62047B1 - Метод за получаване на производни на пиримидина - Google Patents
Метод за получаване на производни на пиримидина Download PDFInfo
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- BG62047B1 BG62047B1 BG97737A BG9773793A BG62047B1 BG 62047 B1 BG62047 B1 BG 62047B1 BG 97737 A BG97737 A BG 97737A BG 9773793 A BG9773793 A BG 9773793A BG 62047 B1 BG62047 B1 BG 62047B1
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- 238000000034 method Methods 0.000 title claims abstract description 81
- 238000002360 preparation method Methods 0.000 title claims abstract description 56
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title claims 2
- 150000003230 pyrimidines Chemical class 0.000 title claims 2
- 150000001875 compounds Chemical class 0.000 claims abstract description 336
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 42
- 239000001257 hydrogen Substances 0.000 claims abstract description 39
- 150000002431 hydrogen Chemical class 0.000 claims abstract description 31
- 229910052751 metal Inorganic materials 0.000 claims abstract description 27
- 239000002184 metal Substances 0.000 claims abstract description 27
- 229910052736 halogen Inorganic materials 0.000 claims abstract description 24
- 150000002367 halogens Chemical class 0.000 claims abstract description 24
- 125000005843 halogen group Chemical group 0.000 claims abstract description 17
- 125000002252 acyl group Chemical group 0.000 claims abstract description 10
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 claims abstract description 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 7
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 191
- PYOKUURKVVELLB-UHFFFAOYSA-N trimethyl orthoformate Chemical compound COC(OC)OC PYOKUURKVVELLB-UHFFFAOYSA-N 0.000 claims description 62
- 239000000203 mixture Substances 0.000 claims description 61
- 239000011541 reaction mixture Substances 0.000 claims description 39
- 238000006243 chemical reaction Methods 0.000 claims description 32
- 239000002585 base Substances 0.000 claims description 28
- -1 CSNH 2 Chemical group 0.000 claims description 26
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- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims description 18
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- 125000003545 alkoxy group Chemical group 0.000 claims description 16
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- 125000004093 cyano group Chemical group *C#N 0.000 claims description 10
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 10
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- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims description 9
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- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims description 2
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- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- PWLNAUNEAKQYLH-UHFFFAOYSA-N butyric acid octyl ester Natural products CCCCCCCCOC(=O)CCC PWLNAUNEAKQYLH-UHFFFAOYSA-N 0.000 description 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 description 1
- 239000000292 calcium oxide Substances 0.000 description 1
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 1
- 125000001589 carboacyl group Chemical group 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 150000008280 chlorinated hydrocarbons Chemical class 0.000 description 1
- 125000001309 chloro group Chemical group Cl* 0.000 description 1
- 229940125898 compound 5 Drugs 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- AQEFLFZSWDEAIP-UHFFFAOYSA-N di-tert-butyl ether Chemical compound CC(C)(C)OC(C)(C)C AQEFLFZSWDEAIP-UHFFFAOYSA-N 0.000 description 1
- 125000003963 dichloro group Chemical group Cl* 0.000 description 1
- 125000002587 enol group Chemical group 0.000 description 1
- XUCNUKMRBVNAPB-UHFFFAOYSA-N fluoroethene Chemical compound FC=C XUCNUKMRBVNAPB-UHFFFAOYSA-N 0.000 description 1
- 235000019256 formaldehyde Nutrition 0.000 description 1
- WBJINCZRORDGAQ-UHFFFAOYSA-N formic acid ethyl ester Natural products CCOC=O WBJINCZRORDGAQ-UHFFFAOYSA-N 0.000 description 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 description 1
- 125000001072 heteroaryl group Chemical group 0.000 description 1
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 101150035614 mbl-1 gene Proteins 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- NBTOZLQBSIZIKS-UHFFFAOYSA-N methoxide Chemical compound [O-]C NBTOZLQBSIZIKS-UHFFFAOYSA-N 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 230000011987 methylation Effects 0.000 description 1
- 238000007069 methylation reaction Methods 0.000 description 1
- UUIQMZJEGPQKFD-UHFFFAOYSA-N n-butyric acid methyl ester Natural products CCCC(=O)OC UUIQMZJEGPQKFD-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 description 1
- LVTJOONKWUXEFR-FZRMHRINSA-N protoneodioscin Natural products O(C[C@@H](CC[C@]1(O)[C@H](C)[C@@H]2[C@]3(C)[C@H]([C@H]4[C@@H]([C@]5(C)C(=CC4)C[C@@H](O[C@@H]4[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@H](CO)O4)CC5)CC3)C[C@@H]2O1)C)[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1 LVTJOONKWUXEFR-FZRMHRINSA-N 0.000 description 1
- 125000003373 pyrazinyl group Chemical group 0.000 description 1
- 125000004076 pyridyl group Chemical group 0.000 description 1
- 125000000714 pyrimidinyl group Chemical group 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Substances [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 238000000935 solvent evaporation Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000004306 triazinyl group Chemical group 0.000 description 1
- 239000013638 trimer Substances 0.000 description 1
- 125000005289 uranyl group Chemical group 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/12—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909024992A GB9024992D0 (en) | 1990-11-16 | 1990-11-16 | Chemical progress |
| GB909024960A GB9024960D0 (en) | 1990-11-16 | 1990-11-16 | Chemical process |
| GB919110592A GB9110592D0 (en) | 1991-05-16 | 1991-05-16 | Chemical process |
| GB919112832A GB9112832D0 (en) | 1991-06-14 | 1991-06-14 | Chemical process |
| GB919112833A GB9112833D0 (en) | 1991-06-14 | 1991-06-14 | Chemical process |
| GB919113911A GB9113911D0 (en) | 1991-06-27 | 1991-06-27 | Chemical process |
| GB919113914A GB9113914D0 (en) | 1991-06-27 | 1991-06-27 | Chemical process |
| PCT/GB1991/001989 WO1992008703A1 (en) | 1990-11-16 | 1991-11-12 | Process for the preparation of pyrimidine compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG97737A BG97737A (bg) | 1994-03-31 |
| BG62047B1 true BG62047B1 (bg) | 1999-01-29 |
Family
ID=27562839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG97737A BG62047B1 (bg) | 1990-11-16 | 1993-05-14 | Метод за получаване на производни на пиримидина |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5847138A (cs) |
| EP (2) | EP0940394B1 (cs) |
| JP (1) | JP3127159B2 (cs) |
| KR (3) | KR100231969B1 (cs) |
| CN (2) | CN1040749C (cs) |
| AT (2) | ATE194601T1 (cs) |
| AU (1) | AU646313B2 (cs) |
| BG (1) | BG62047B1 (cs) |
| BR (1) | BR9107087A (cs) |
| CA (2) | CA2347599C (cs) |
| CZ (2) | CZ283215B6 (cs) |
| DE (2) | DE69132318T2 (cs) |
| DK (2) | DK0940394T3 (cs) |
| ES (2) | ES2148155T3 (cs) |
| GB (1) | GB9122430D0 (cs) |
| GR (1) | GR3034428T3 (cs) |
| HU (1) | HU213186B (cs) |
| IE (1) | IE913753A1 (cs) |
| IL (4) | IL99884A (cs) |
| MY (1) | MY107905A (cs) |
| NZ (2) | NZ240438A (cs) |
| PH (1) | PH31039A (cs) |
| PT (1) | PT99509B (cs) |
| RO (1) | RO111078B1 (cs) |
| SK (1) | SK281055B6 (cs) |
| WO (1) | WO1992008703A1 (cs) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9405492D0 (en) * | 1994-03-21 | 1994-05-04 | Zeneca Ltd | Chemical compounds |
| GB9415291D0 (en) * | 1994-07-28 | 1994-09-21 | Zeneca Ltd | Chemical process |
| FR2737086B1 (fr) * | 1995-07-24 | 1997-08-22 | Rhone Poulenc Agrochimie | Composition fongicide comprenant un compose analogue de la strobilurine |
| FR2739529B1 (fr) * | 1995-10-05 | 1997-10-31 | Rhone Poulenc Agrochimie | Composition fongicide comprenant un compose analogue de la strobilurine |
| GB9617351D0 (en) * | 1996-08-19 | 1996-10-02 | Zeneca Ltd | Chemical process |
| EP0929543B1 (en) * | 1996-09-26 | 2001-10-31 | Syngenta Participations AG | Herbicidal composition |
| GB9622345D0 (en) * | 1996-10-28 | 1997-01-08 | Zeneca Ltd | Chemical process |
| US5849910A (en) * | 1997-09-05 | 1998-12-15 | American Cyanamid Company | Process for the preparation of unsymmetrical 4,6-bis aryloxy-pyrimidine compounds |
| US6277856B1 (en) * | 1998-09-25 | 2001-08-21 | American Cynamid Co. | Fungicidal mixtures |
| US6699874B2 (en) | 1999-09-24 | 2004-03-02 | Basf Aktiengesellschaft | Fungicidal mixtures |
| US6608199B2 (en) | 2000-07-07 | 2003-08-19 | Syngenta Limited | Synthesis of chlorinated pyrimidines |
| US6982331B2 (en) | 2001-06-08 | 2006-01-03 | Syngenta Crop Protection, Inc. | Synthesis of chlorinated pyrimidines |
| GB0508422D0 (en) * | 2005-04-26 | 2005-06-01 | Syngenta Ltd | Chemical process |
| CN100427481C (zh) | 2005-05-26 | 2008-10-22 | 沈阳化工研究院 | 一种芳基醚类化合物及其制备与应用 |
| US20080257549A1 (en) | 2006-06-08 | 2008-10-23 | Halliburton Energy Services, Inc. | Consumable Downhole Tools |
| US20070284114A1 (en) | 2006-06-08 | 2007-12-13 | Halliburton Energy Services, Inc. | Method for removing a consumable downhole tool |
| US7591318B2 (en) | 2006-07-20 | 2009-09-22 | Halliburton Energy Services, Inc. | Method for removing a sealing plug from a well |
| GB0619941D0 (en) | 2006-10-09 | 2006-11-15 | Syngenta Ltd | Chemical process |
| IL180134A0 (en) | 2006-12-17 | 2007-07-04 | David Ovadia | Process for the preparation of substituted cyanophenoxy-pyrimidinyloxy -phenyl acrylate derivatives |
| IL181125A0 (en) | 2007-02-01 | 2007-07-04 | Maktheshim Chemical Works Ltd | Polymorphs of 3-(e)-2-{2-[6-(2- |
| US20080202764A1 (en) | 2007-02-22 | 2008-08-28 | Halliburton Energy Services, Inc. | Consumable downhole tools |
| US8235102B1 (en) | 2008-03-26 | 2012-08-07 | Robertson Intellectual Properties, LLC | Consumable downhole tool |
| US8327926B2 (en) | 2008-03-26 | 2012-12-11 | Robertson Intellectual Properties, LLC | Method for removing a consumable downhole tool |
| CN102190629B (zh) * | 2010-03-17 | 2012-12-12 | 淄博万昌科技股份有限公司 | 利用丙烯腈废气氢氰酸制备嘧菌酯的方法 |
| CN102190640B (zh) * | 2010-03-17 | 2013-03-27 | 淄博万昌科技股份有限公司 | 利用丙烯腈废气氢氰酸制备3-(α-甲氧基)-亚甲基苯并呋喃-2(3H)-酮的方法 |
| CN102199137B (zh) * | 2010-03-24 | 2013-03-20 | 淄博万昌科技股份有限公司 | 一种制备3-(α-甲氧基)-亚甲基苯并呋喃-2(3H)-酮的方法 |
| CN102199127B (zh) * | 2010-03-24 | 2012-12-12 | 淄博万昌科技股份有限公司 | 一种制备嘧菌酯的方法 |
| CN101973943B (zh) * | 2010-09-26 | 2012-11-21 | 重庆紫光化工股份有限公司 | (e)-2-[2-(6-氯嘧啶-4-基氧)苯基]-3-甲氧基丙烯酸甲酯的制备方法 |
| CN102241651B (zh) * | 2011-05-25 | 2013-01-23 | 江苏七洲绿色化工股份有限公司 | 一种嘧菌酯中间体的制备方法 |
| CN102276538B (zh) * | 2011-08-12 | 2015-01-28 | 河北威远生化农药有限公司 | 嘧菌酯及其关键中间体的制备方法 |
| CN102417498B (zh) * | 2011-08-24 | 2015-09-09 | 重庆紫光化工股份有限公司 | 3-(α-甲氧基)甲烯基苯并呋喃-2(3H)-酮的合成方法 |
| CN102311392B (zh) * | 2011-08-24 | 2014-01-22 | 重庆紫光化工股份有限公司 | 嘧菌酯及其合成中专用中间体的合成方法 |
| CN102399195A (zh) * | 2011-12-08 | 2012-04-04 | 北京颖新泰康国际贸易有限公司 | 一种嘧菌酯中间体的合成方法 |
| CN103664846B (zh) * | 2012-08-31 | 2015-10-21 | 中国中化股份有限公司 | 一种3-(α-甲氧基)-亚甲基苯并呋喃-2(3氢)-酮的制备方法 |
| CN103214423B (zh) * | 2013-03-20 | 2016-03-16 | 北京颖泰嘉和生物科技股份有限公司 | 一种丙烯酸酯类化合物的制备方法 |
| CN103265496B (zh) | 2013-05-16 | 2015-02-25 | 北京颖泰嘉和生物科技有限公司 | 一种嘧菌酯的制备方法 |
| TWI621614B (zh) | 2013-05-28 | 2018-04-21 | 科麥農股份有限公司 | 4,6-雙(芳氧基)嘧啶衍生物的製備方法 |
| CN103467387B (zh) | 2013-09-05 | 2016-03-16 | 北京颖泰嘉和生物科技股份有限公司 | 一种制备嘧菌酯及其中间体的方法 |
| WO2015102016A1 (en) * | 2013-12-31 | 2015-07-09 | Bhagiradha Chemicals & Industries Limited | Process for the preparation of methyl 2-[2-(6-chloropyrimidin-4-yloxy) phenyl]-3,3- dimethoxypropionate |
| CN104311493B (zh) * | 2014-09-16 | 2016-08-24 | 重庆紫光国际化工有限责任公司 | 嘧菌酯的合成方法 |
| CN104557825B (zh) * | 2015-01-04 | 2016-06-15 | 尹山红 | 一种回收3-(α-甲氧基)-亚甲基苯并呋喃-2(3氢)-酮的方法 |
| CN104926736B (zh) * | 2015-05-29 | 2019-05-17 | 重庆紫光化工股份有限公司 | 一种嘧菌酯及其中间体的合成方法 |
| CN104974097B (zh) * | 2015-05-29 | 2018-04-17 | 重庆紫光化工股份有限公司 | 一种嘧菌酯的合成方法 |
| CN105968057B (zh) * | 2016-05-13 | 2019-03-26 | 安徽广信农化股份有限公司 | 一种嘧菌酯的合成工艺 |
| CN107353255A (zh) * | 2017-06-29 | 2017-11-17 | 上海应用技术大学 | 一种嘧菌酯中间体的合成方法 |
| CN109721545B (zh) | 2017-10-31 | 2020-09-11 | 南通泰禾化工股份有限公司 | 一种嘧菌酯中间体的制备方法 |
| CN110294716B (zh) | 2018-03-23 | 2021-05-07 | 帕潘纳(北京)科技有限公司 | 一种嘧菌酯及其中间体的制备方法 |
| CN108558818B (zh) * | 2018-04-28 | 2020-08-28 | 帕潘纳(北京)科技有限公司 | 一种甲氧甲烯基化合物的制备方法 |
| TWI705961B (zh) * | 2018-11-28 | 2020-10-01 | 興農股份有限公司 | 亞托敏的製備方法 |
| CN112574125A (zh) * | 2020-12-01 | 2021-03-30 | 维讯化工（南京）有限公司 | 一种提高嘧菌酯转化率的方法 |
| CN116239540B (zh) * | 2021-12-08 | 2025-04-25 | 南通泰禾化工股份有限公司 | 一种嘧菌酯中间体的制备方法及其应用 |
| CN114957134B (zh) | 2022-05-26 | 2024-07-16 | 安徽广信农化股份有限公司 | 一种制备嘧菌酯及其中间体的方法 |
| CN116924997A (zh) * | 2023-07-14 | 2023-10-24 | 江苏剑牌农化股份有限公司 | 一种嘧菌酯中间体的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ213630A (en) * | 1984-10-19 | 1990-02-26 | Ici Plc | Acrylic acid derivatives and fungicidal compositions |
| EP0242081B1 (en) * | 1986-04-17 | 1994-04-27 | Zeneca Limited | Fungicides |
| GB8903019D0 (en) * | 1989-02-10 | 1989-03-30 | Ici Plc | Fungicides |
| GB8908875D0 (en) * | 1989-04-19 | 1989-06-07 | Ici Plc | Fungicides |
-
1991
- 1991-10-23 GB GB919122430A patent/GB9122430D0/en active Pending
- 1991-10-25 IE IE375391A patent/IE913753A1/en not_active IP Right Cessation
- 1991-10-29 IL IL9988491A patent/IL99884A/en not_active IP Right Cessation
- 1991-10-29 IL IL12716791A patent/IL127167A/en not_active IP Right Cessation
- 1991-10-29 IL IL11770991A patent/IL117709A/xx not_active IP Right Cessation
- 1991-11-01 NZ NZ240438A patent/NZ240438A/en not_active IP Right Cessation
- 1991-11-01 NZ NZ248281A patent/NZ248281A/xx not_active IP Right Cessation
- 1991-11-04 PH PH43387A patent/PH31039A/en unknown
- 1991-11-11 MY MYPI91002082A patent/MY107905A/en unknown
- 1991-11-12 DE DE69132318T patent/DE69132318T2/de not_active Expired - Lifetime
- 1991-11-12 DE DE69132971T patent/DE69132971T2/de not_active Expired - Lifetime
- 1991-11-12 HU HU9301296A patent/HU213186B/hu unknown
- 1991-11-12 AT AT91919721T patent/ATE194601T1/de not_active IP Right Cessation
- 1991-11-12 JP JP03518202A patent/JP3127159B2/ja not_active Expired - Lifetime
- 1991-11-12 DK DK99100461T patent/DK0940394T3/da active
- 1991-11-12 CA CA002347599A patent/CA2347599C/en not_active Expired - Lifetime
- 1991-11-12 SK SK483-93A patent/SK281055B6/sk not_active IP Right Cessation
- 1991-11-12 BR BR919107087A patent/BR9107087A/pt not_active IP Right Cessation
- 1991-11-12 EP EP99100461A patent/EP0940394B1/en not_active Expired - Lifetime
- 1991-11-12 DK DK91919721T patent/DK0592435T3/da active
- 1991-11-12 AU AU88708/91A patent/AU646313B2/en not_active Expired
- 1991-11-12 CZ CZ961649A patent/CZ283215B6/cs not_active IP Right Cessation
- 1991-11-12 WO PCT/GB1991/001989 patent/WO1992008703A1/en active IP Right Grant
- 1991-11-12 EP EP91919721A patent/EP0592435B1/en not_active Expired - Lifetime
- 1991-11-12 CA CA002095848A patent/CA2095848C/en not_active Expired - Lifetime
- 1991-11-12 ES ES91919721T patent/ES2148155T3/es not_active Expired - Lifetime
- 1991-11-12 RO RO93-00660A patent/RO111078B1/ro unknown
- 1991-11-12 CZ CZ93852A patent/CZ281966B6/cs not_active IP Right Cessation
- 1991-11-12 KR KR1019930701458A patent/KR100231969B1/ko not_active Expired - Lifetime
- 1991-11-12 AT AT99100461T patent/ATE215077T1/de not_active IP Right Cessation
- 1991-11-12 ES ES99100461T patent/ES2175860T3/es not_active Expired - Lifetime
- 1991-11-14 CN CN91110782A patent/CN1040749C/zh not_active Expired - Lifetime
- 1991-11-14 PT PT99509A patent/PT99509B/pt not_active IP Right Cessation
-
1993
- 1993-05-14 BG BG97737A patent/BG62047B1/bg unknown
-
1995
- 1995-06-07 US US08/479,242 patent/US5847138A/en not_active Expired - Lifetime
-
1996
- 1996-03-28 IL IL11770996A patent/IL117709A0/xx unknown
-
1997
- 1997-09-15 CN CN97118615A patent/CN1096454C/zh not_active Expired - Lifetime
-
1999
- 1999-05-31 KR KR1019997004772A patent/KR100242581B1/ko not_active Expired - Lifetime
- 1999-05-31 KR KR1019997004771A patent/KR100242580B1/ko not_active Expired - Lifetime
-
2000
- 2000-09-18 GR GR20000402117T patent/GR3034428T3/el unknown
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